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Coronary CT Angiography Current applications in clinical practice and promise for the future Samuel Wann MD, MACC

Coronary CT Angiography Current applications in clinical practice and promise for the future Samuel Wann MD, MACC

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Page 1: Coronary CT Angiography Current applications in clinical practice and promise for the future Samuel Wann MD, MACC

Coronary CT AngiographyCurrent applications in clinical

practice and promise for the future

Samuel Wann MD, MACC

Page 2: Coronary CT Angiography Current applications in clinical practice and promise for the future Samuel Wann MD, MACC

WISCONSIN HEART HOSPITAL

Page 3: Coronary CT Angiography Current applications in clinical practice and promise for the future Samuel Wann MD, MACC
Page 4: Coronary CT Angiography Current applications in clinical practice and promise for the future Samuel Wann MD, MACC

HOW TO…

• 16 or 64 slice scanner

• Cardiac gating – HR <70 bpm

• Regular rhythm

• Properly timed IV contrast bolus

• Breath-hold

• Reconstruct images at various phases of cardiac cycle

Page 5: Coronary CT Angiography Current applications in clinical practice and promise for the future Samuel Wann MD, MACC

Axial Images

• Thin MIP

• Adjust window and contrast levels

• Scroll thru all images

• Select phase with least motion artifact

• Multiplanar reformats as needed

Page 6: Coronary CT Angiography Current applications in clinical practice and promise for the future Samuel Wann MD, MACC

Heart window

Page 7: Coronary CT Angiography Current applications in clinical practice and promise for the future Samuel Wann MD, MACC

Lung window Bone window

Page 8: Coronary CT Angiography Current applications in clinical practice and promise for the future Samuel Wann MD, MACC

Beam hardening “streak” artifact

Page 9: Coronary CT Angiography Current applications in clinical practice and promise for the future Samuel Wann MD, MACC

10% phase

20% 30% 40%

50% 60% 70% 80%

75%

Page 10: Coronary CT Angiography Current applications in clinical practice and promise for the future Samuel Wann MD, MACC
Page 11: Coronary CT Angiography Current applications in clinical practice and promise for the future Samuel Wann MD, MACC

RCA mpr

Page 12: Coronary CT Angiography Current applications in clinical practice and promise for the future Samuel Wann MD, MACC

LAD mpr

Page 13: Coronary CT Angiography Current applications in clinical practice and promise for the future Samuel Wann MD, MACC

LCX mpr

Page 14: Coronary CT Angiography Current applications in clinical practice and promise for the future Samuel Wann MD, MACC

Review of volumetric dataset

• Curved reformatted images

• 3D reconstructions

• “IVUS” view

• Functional analysis

Page 15: Coronary CT Angiography Current applications in clinical practice and promise for the future Samuel Wann MD, MACC

3D volume rendering

Page 16: Coronary CT Angiography Current applications in clinical practice and promise for the future Samuel Wann MD, MACC

LAD crf

Page 17: Coronary CT Angiography Current applications in clinical practice and promise for the future Samuel Wann MD, MACC

RCA crf

Page 18: Coronary CT Angiography Current applications in clinical practice and promise for the future Samuel Wann MD, MACC
Page 19: Coronary CT Angiography Current applications in clinical practice and promise for the future Samuel Wann MD, MACC

“IVUS” view

Page 20: Coronary CT Angiography Current applications in clinical practice and promise for the future Samuel Wann MD, MACC
Page 21: Coronary CT Angiography Current applications in clinical practice and promise for the future Samuel Wann MD, MACC

Anomalous Right Coronary Artery

Page 22: Coronary CT Angiography Current applications in clinical practice and promise for the future Samuel Wann MD, MACC

Right Coronary Artery Catheterization Comparison

Cardiac CatheterizationCardiac Catheterization MSCTMSCT

Page 23: Coronary CT Angiography Current applications in clinical practice and promise for the future Samuel Wann MD, MACC
Page 24: Coronary CT Angiography Current applications in clinical practice and promise for the future Samuel Wann MD, MACC

Proximal LAD Coronary StentMSCT

Page 25: Coronary CT Angiography Current applications in clinical practice and promise for the future Samuel Wann MD, MACC
Page 26: Coronary CT Angiography Current applications in clinical practice and promise for the future Samuel Wann MD, MACC

Occluded LAD/RCAMSCT

Page 27: Coronary CT Angiography Current applications in clinical practice and promise for the future Samuel Wann MD, MACC

3D Reconstruction Coronary bypass

Page 28: Coronary CT Angiography Current applications in clinical practice and promise for the future Samuel Wann MD, MACC

35 yo woman in ER for atypical chest pain. Normal ecg & troponin

Page 29: Coronary CT Angiography Current applications in clinical practice and promise for the future Samuel Wann MD, MACC

48 year old man in ERsudden severe chest pain/dyspnea 2 hours duration

History of hypertension

Normal troponin

ECG shows LVH with strain

Page 30: Coronary CT Angiography Current applications in clinical practice and promise for the future Samuel Wann MD, MACC
Page 31: Coronary CT Angiography Current applications in clinical practice and promise for the future Samuel Wann MD, MACC

Aortic dissection

Page 32: Coronary CT Angiography Current applications in clinical practice and promise for the future Samuel Wann MD, MACC
Page 33: Coronary CT Angiography Current applications in clinical practice and promise for the future Samuel Wann MD, MACC

Non-coronary CV structures

• ventricles

• pericardium

• atria, atrial appendage

• pulmonary veins and arteries

• aorta

• valves

Page 34: Coronary CT Angiography Current applications in clinical practice and promise for the future Samuel Wann MD, MACC

LV functional analysis

Page 35: Coronary CT Angiography Current applications in clinical practice and promise for the future Samuel Wann MD, MACC
Page 36: Coronary CT Angiography Current applications in clinical practice and promise for the future Samuel Wann MD, MACC
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Page 38: Coronary CT Angiography Current applications in clinical practice and promise for the future Samuel Wann MD, MACC
Page 39: Coronary CT Angiography Current applications in clinical practice and promise for the future Samuel Wann MD, MACC

32 yo woman

3 yr hx

atypical

chest

pain

Page 40: Coronary CT Angiography Current applications in clinical practice and promise for the future Samuel Wann MD, MACC
Page 41: Coronary CT Angiography Current applications in clinical practice and promise for the future Samuel Wann MD, MACC
Page 42: Coronary CT Angiography Current applications in clinical practice and promise for the future Samuel Wann MD, MACC

92 yo woman

Progressivedyspnea

Page 43: Coronary CT Angiography Current applications in clinical practice and promise for the future Samuel Wann MD, MACC
Page 44: Coronary CT Angiography Current applications in clinical practice and promise for the future Samuel Wann MD, MACC

Non-CV Structures

• Lungs and airway

• Mediastinum

• Bones

• Lower neck and upper abdomen

Page 45: Coronary CT Angiography Current applications in clinical practice and promise for the future Samuel Wann MD, MACC
Page 46: Coronary CT Angiography Current applications in clinical practice and promise for the future Samuel Wann MD, MACC
Page 47: Coronary CT Angiography Current applications in clinical practice and promise for the future Samuel Wann MD, MACC
Page 48: Coronary CT Angiography Current applications in clinical practice and promise for the future Samuel Wann MD, MACC

CIRCUMFLEX STENOSIS

Page 49: Coronary CT Angiography Current applications in clinical practice and promise for the future Samuel Wann MD, MACC

Patients

Age % with CAD by

catheterizati

on

Arteries evaluat

ed

Uneval-uable

arteries

Sens-itivity

Speci-ficity

Negative

predictive value

Heart

rate(bpm)

Dosemodula

tion

Leschka 67 60 70% >1.5 mm 0 94% 97% 99% 66 No

Ropers 82 59 31% >1.5 mm 4% 95% 93% 99% 59 Yes

Fine 66 62 >1.5 mm 6% 95% 96% 95% No

Leber 59 64 49% All 7% 73% 97% 99% 63 Yes

Raff 70 59 54% All 12% 86% 95% 98% 58 No

Mollet 52 60 75% All 2% 99% 95% 99% No

WeightedAverage for all

61 54% 3% 90% 95% 98%

64 slice Computed Tomography - Sensitivity & specificity