10
Control theory and homeostasis Control theory That branch of mathematics and engineering which deals with t design, identification and analysis of systems with a view to controlling them, i.e., to make them perform specific tasks o behave in a desired way Homeostasis The ability and tendency of certain systems to maintain a rel constant internal state in spite of changes in external condi ZAP1

Control theory and homeostasis

  • Upload
    raheem

  • View
    36

  • Download
    0

Embed Size (px)

DESCRIPTION

ZRT1 ZRT@ ZAP1. Control theory and homeostasis. Control theory That branch of mathematics and engineering which deals with the design, identification and analysis of systems with a view towards controlling them, i.e., to make them perform specific tasks or to behave in a desired way. - PowerPoint PPT Presentation

Citation preview

Page 1: Control theory and homeostasis

Control theory and homeostasis

Control theory

That branch of mathematics and engineering which deals with thedesign, identification and analysis of systems with a view towardscontrolling them, i.e., to make them perform specific tasks or to behave in a desired way

Homeostasis

The ability and tendency of certain systems to maintain a relativelyconstant internal state in spite of changes in external conditions

ZRT1ZRT@ZAP1

Page 2: Control theory and homeostasis

Human designed control systems

Page 3: Control theory and homeostasis

Human designed control systems

Cornelis Drebbel 1620

Page 4: Control theory and homeostasis

Human designed control systems

satellite attitude control

Page 5: Control theory and homeostasis

controller processactuator

sensor

inputfilter

+controlsignalreference

disturbance

_output

block diagram of a basic feedback control

Page 6: Control theory and homeostasis

Calcium homeostasis

Page 7: Control theory and homeostasis

TumbleCW

10µm

RunCCW

Increasing Chemical Gradient

Bacterial chemotaxis

biased random walk:

increase concentration -> decreased tumbling frequency

Page 8: Control theory and homeostasis

Tethering Analysis

Agonist changes rotational bias Kirby et al (JBC, 1999)

perfect adaptation of tumbling frequency

Page 9: Control theory and homeostasis

Zn

ZRT1ZRT2

ZnZRT1ZRT1ZAP1

ZAP1

intracellular nutrient homeostasis

a simplified model for Zinc homeostasis

Page 10: Control theory and homeostasis

Searching Pubmed

“homeostasis” 126408 hits

“control theory” 432

“homeostasis” AND “control theory” 27