Case 1 Hemiplegia with aphasia

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    CASE SUMMARY

    Patient named Rattan Nagpal 64 year old female a k/c/o HTNand seizure disorder presented with h/o deviation of angle ofmouth since today 3.30 pm of acute onset associated withdifficulty in speech.She also gives h/o weakness in the right

    upper and lower limb of acute onset progressive innature.Patient also gives h/o Severe headache and oneepisode of vomiting.

    O/E she was found to have elevated BP at 180/100

    mmHg.Aphasia was present though she was conscious.

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    The power in Rt upper and lower limb was..Plantar

    response on the right side was extensor.She was

    initially taken to SGRH were CT brain was doneWhich showed Fronto-parietal bleed with mass

    effect. Patient was put on Inj Mannitol in BLK

    emergency and was shifted to MICU.Inj Lasix, Dexa, Aragon and strocit were

    started. Initial investigations showed raised TLC at

    15500, Serum electrolytes,LFT were WNL.KFT were

    mildly deranged with creat-1.4 uric acid-7.6.

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    ECG showed occasional VPCs hence Beta

    Blocker Was started. ECHO was done which

    was non Contributory..Inj Taxim was started Patient turned

    restless,irritable and Neurology opinion was

    taken on 9/10/11 and They advised CT angio of

    brain which was deferred as patient was very

    restless. Inj Nimodepin was 60mg TDS and NTG

    infusion were started to maintain BP at Systolic

    150 mmHg.

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    On 10/9/11

    Patient turned febrile , TLC-raised to 23500 thoughserum electrolytes were WNL. Blood and urine

    cultures were sent and antibiotics were modifiedto Inj Dalacin.

    As patient continued to deteriorate with worsening

    Sensorium, repeat CT Brain was done which didntshow any marked variation from previous CT brain

    Findings .Inj Dexa stopped and Inj Mannitol wasw/h. Patient deterioted further on 11/9/11, withdrowsiness increasing patient not responding tocommands, pre-renal azotemia and CXRshowing Rt LZ haziness.

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    At 6.20 pm patient started desaturating ABGdone showed Hypoxemia hence wasintubated.Previously sent cultures werefound to be sterile.ET tube secretionswere sent for c/s and on 13/09/11 it camepositive for MRSA.Inj Lenozolid was

    added.Counts and KFT showingimprovement.On 15/9/11 Patientdeveloped fluctuating BP which wasconfirmed by manual assessment

    requireing Noradrenaline on & off, ECGdone s/o AF and PVR and Inj Cardaroneinfusion started with cardiology opinion.On 16/09/11 TLC again raised to 18200

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    and KFT deterioted.Repeat CXR showing Rt LZhaziness . Blood c/s and Urine c/s were

    sent.on 18/9/11 Blood culture came positivefor Pseudomonas auriginosa and urine cultureshowed growth of E Coli (ESBL +ve).Inj

    Meropenam were added based on senistivityreports. In view of raising s.urea andcreatinine levels dialysis was done on 17/9/11.Patients sensorium started improving on 18th

    and 19th and counts ands renal parametersstarted improving.Inj Dalacin and Linid werestopped on 19/9/11.

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    MRI brain done on 19/9/11 was s/o earlysubacute hematoma in Lt gangliocapsular

    region and adjacent temporal lobe.smallsubacute infarct in medial Lt tempero-occipetal lobe.Repeat ET tube c/s wasdone on 21/9/11 which showed

    Burkholderia cepacia and Inj Aztreonamwas added to the treatment.Patient wasmonitored continuously with expert advicefrom nephrologist and

    neurologist.Gradually patients sensoriumimproved over the next 4 days and he wasextubated on 24/9/11.

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    All the vital organs parameters wereimproving incluiding KFTs,Electrolytes andothers.Patient again developed fever on28/9/11 and Inj Fluconozole was startedsending repeat blood culture and itshowed growth of candida tropicalis and

    hence flucanozole was replaced withvoraconazole.With improvement incondition patient was moved to wards on1/10/11.Patient was continued on

    conservative medications and graduallyshifted over to oral antibiotics and wasdischarged on 12/10/11 in stable condition.