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Bimonthly Meeting on Jan. 23, 2009 Chemical Information on Phantom by Gaussian Function Amarjeet Bhullar

Bimonthly Meeting on Jan. 23, 2009

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Chemical Information on Phantom by Gaussian Function. Amarjeet Bhullar. Bimonthly Meeting on Jan. 23, 2009. 7*7=49 Voxels. Cho=3097.32. NAA=4818.51. Cre=3726.94. 15*15=225 Voxels. Cho=8497.17. NAA=13166.20. Cre=10162.30. 7*7=49 Voxels and 15*15=225 Voxels. - PowerPoint PPT Presentation

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  • Bimonthly Meeting on Jan. 23, 2009Chemical Information on Phantom by Gaussian FunctionAmarjeet Bhullar

  • 7*7=49 VoxelsCho=3097.32Cre=3726.94NAA=4818.51

    Voxel 1 to 49GaussianCho/Cre0.831Cho/NAA0.642

  • 15*15=225 VoxelsCho=8497.17Cre=10162.30NAA=13166.20

    Voxel 1 to 225GaussianCho/Cre0.836Cho/NAA0.645

  • 7*7=49 Voxels and 15*15=225 Voxels

  • Comparison between 7*7 and 15*15 Spectra

    Voxel 1 to 49GaussianCho/Cre0.831Cho/NAA0.642

    Voxel 1 to 225GaussianCho/Cre0.836Cho/NAA0.645

  • Metabolite peaks fit by Gaussian function

  • Cho=26.4059Cre=38.3233NAA=50.3961Calculation of Metabolite Concentrations

  • Cho=30.047Cre=45.8772NAA=51.899Calculation of Metabolite Concentrations

  • Cho=27.7975Cre=39.7157NAA=50.4718Calculation of Metabolite Concentrations

  • Cho=34.0246Cre=49.0628NAA=60.5868Calculation of Metabolite Concentrations

  • Cho=123.506Cre=174.144NAA=220.372Calculation of Metabolite Concentrations

  • Cho=67.1154Cre=74.2094NAA=93.7448Calculation of Metabolite Concentrations

  • Voxel Comparison

    15*15ChoCreNAAVox#3326.405938.323350.3961Vox#3430.047045.877251.8990Vox#4827.797539.715750.4718Vox#4934.024649.062860.5869Total Con.110.6558172.979213.3538

    15*15ChoCreNAAVox#33+34+48+49123.506174.144220.372

    7*7ChoCreNAAVox#967.115474.209493.7448

  • Conclusion:Even difference of smallest fraction between voxel size (7*7 and 15*15) creates differentmetabolite concentrations.Suggestions are welcome

  • Row Wise Distribution of Cho/Cre

  • Row Wise Distribution of Cho/NAA

  • Metabolite Ratios by Gaussian function

    Voxel #1GaussianCho/Cre0.751014Cho/NAA0.82592

    Voxel #2GaussianCho/Cre0.920288Cho/NAA1.204818

    Voxel #3GaussianCho/Cre1.026504Cho/NAA1.00366

    Voxel #4GaussianCho/Cre0.934274Cho/NAA1.265779

  • Metabolite Ratios by Gaussian function

    Voxel #4GaussianCho/Cre0.934274Cho/NAA1.265779

    Voxel #5GaussianCho/Cre0.913693Cho/NAA0.950665

    Voxel #6GaussianCho/Cre0.905497Cho/NAA1.00024

    Voxel #7GaussianCho/Cre0.890625Cho/NAA1.284948

  • Metabolite Ratios by Gaussian function

    Voxel #8GaussianCho/Cre0.860931Cho/NAA0.544306

    Voxel #9GaussianCho/Cre0.904406Cho/NAA0.715937

    Voxel #10GaussianCho/Cre0.817914Cho/NAA0.667594

    Voxel #11GaussianCho/Cre0.836532Cho/NAA0.680032

  • Metabolite Ratios by Gaussian function

    Voxel #12GaussianCho/Cre0.859035Cho/NAA0.683185

    Voxel #13GaussianCho/Cre0.84962Cho/NAA0.697155

    Voxel #14GaussianCho/Cre0.770389Cho/NAA0.74367

    Voxel #15GaussianCho/Cre0.915505Cho/NAA0.559509

  • Metabolite Ratios by Gaussian function

    Voxel #16GaussianCho/Cre0.89351Cho/NAA0.650015

    Voxel #17GaussianCho/Cre0.807657Cho/NAA0.605227

    Voxel #18GaussianCho/Cre0.807195Cho/NAA0.619962

    Voxel #19GaussianCho/Cre0.839769Cho/NAA0.611889

  • Metabolite Ratios by Gaussian function

    Voxel #20GaussianCho/Cre0.815158Cho/NAA0.617085

    Voxel #21GaussianCho/Cre0.691482Cho/NAA0.592537

    Voxel #22GaussianCho/Cre0.808174Cho/NAA0.48208

    Voxel #23GaussianCho/Cre0.842664Cho/NAA0.615965

  • Metabolite Ratios by Gaussian function

    Voxel #24GaussianCho/Cre0.80954Cho/NAA0.616462

    Voxel #25GaussianCho/Cre0.824471Cho/NAA0.620819

    Voxel #26GaussianCho/Cre0.812873Cho/NAA0.593714

    Voxel #27GaussianCho/Cre0.764973Cho/NAA0.614783

  • Metabolite Ratios by Gaussian function

    Voxel #28GaussianCho/Cre0.693088Cho/NAA0-643046

    Voxel #29GaussianCho/Cre0.820805Cho/NAA0.541781

    Voxel #30GaussianCho/Cre0.863645Cho/NAA0.615628

    Voxel #31GaussianCho/Cre0.822132Cho/NAA0.615398

  • Metabolite Ratios by Gaussian function

    Voxel #32GaussianCho/Cre0.863442Cho/NAA0.64706

    Voxel #33GaussianCho/Cre0.829424Cho/NAA0.630388

    Voxel #34GaussianCho/Cre0.826255Cho/NAA0.64566

    Voxel #35GaussianCho/Cre0.838811Cho/NAA0.755696

  • Metabolite Ratios by Gaussian function

    Voxel #36GaussianCho/Cre0.813257Cho/NAA0.524243

    Voxel #37GaussianCho/Cre0.883596Cho/NAA0.565531

    Voxel #38GaussianCho/Cre0.895173Cho/NAA0.661893

    Voxel #39GaussianCho/Cre0.915392Cho/NAA0.724875

  • Metabolite Ratios by Gaussian function

    Voxel #40GaussianCho/Cre0.933848Cho/NAA0.707293

    Voxel #41GaussianCho/Cre0.877934Cho/NAA0.739058

    Voxel #42GaussianCho/Cre0.89324Cho/NAA0.83322

    Voxel #43GaussianCho/Cre0.620034Cho/NAA0.399859

  • Metabolite Ratios by Gaussian function

    Voxel #44GaussianCho/Cre0.77063Cho/NAA0.522992

    Voxel #45GaussianCho/Cre0.77063Cho/NAA0.529867

    Voxel #46GaussianCho/Cre0.92655Cho/NAA0.663082

    Voxel #47GaussianCho/Cre0.903481Cho/NAA0.627585

  • Metabolite Ratios by Gaussian function

    Voxel #48GaussianCho/Cre0.879797Cho/NAA0.644314

    Voxel #49GaussianCho/Cre0.659546Cho/NAA0.601717

  • Conclusion:All the data reveals that the Gaussian Function is the best fit for MagneticResonance Spectroscopy.Suggestions are welcome