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Bimonthly Meeting on March 27, 2009
Amarjeet Bhullar
MRS on Exam 4633
AB_4633, Aug 22, 2008
S48.5 S58.5 S68.5
Metabolite Ratios by Gaussian function
4.0 3.5 3.0 2.5 2.0 1.5 1.0 0.5-500
0
500
1000
1500
Real Spectrum Baseline Anchor Points
Voxel # 10, S48.4
Sig
nal (
MR
Uni
ts)
ppm4.0 3.5 3.0 2.5 2.0 1.5 1.0 0.5
-250
0
250
500
750
Sig
nal (
MR
Uni
ts)
Voxel # 10, S48.4
Cho
Cr N
AA
ppm
4.0 3.5 3.0 2.5 2.0 1.5 1.0 0.5
0
1000
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4000
5000
Sig
nal (
MR
Uni
ts) Voxel # 16, S48.4
ppm
Real Spectrum Baseline Anchor Points
4.0 3.5 3.0 2.5 2.0 1.5 1.0 0.50
500
1000
1500
2000
2500
Sig
nal (
MR
Uni
ts)
Voxel # 16, S48.4
Cho C
r NA
A
ppm
Vox# Cho Cr NAA10 41.2846 39.1755 45.675916 30.6817 48.0501 73.2585
Metabolite Ratios by Gaussian function
4.0 3.5 3.0 2.5 2.0 1.5 1.0 0.5
-400
0
400
800
1200
Baseline Real Spectrum Anchor Points
Sig
nal (
MR
Uni
ts) Voxel # 17, S48.4
ppm4.0 3.5 3.0 2.5 2.0 1.5 1.0 0.5
-600
-300
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600
Sig
nal (
MR
Uni
ts)
Voxel # 17, S48.4
Cho
Cr
NA
A
ppm
4.0 3.5 3.0 2.5 2.0 1.5 1.0 0.50
1000
2000
3000
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5000
Sig
nal (
MR
Uni
ts)
Voxel # 23, S48.4
ppm
Baseline Real Spectrum Anchor Points
4.0 3.5 3.0 2.5 2.0 1.5 1.0 0.5
0
1000
2000
3000
Sig
nal (
MR
Uni
ts)
ppm
Cho C
r NA
A
Voxel # 23, S48.4
Vox# Cho Cr NAA17 63.4934 52.3584 79.36423 40.3568 51.0405 89.809
Metabolite Ratios by Gaussian function
4.0 3.5 3.0 2.5 2.0 1.5 1.0 0.5-2000
-1000
0
1000
2000
3000
Real Spectrum Baseline Anchor Points
Sig
nal (
MR
Uni
ts)
Voxel # 24, S48.4
ppm4.0 3.5 3.0 2.5 2.0 1.5 1.0 0.5
-1200
-800
-400
0
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800
Sig
nal (
MR
Uni
ts)
Voxel # 24, S48.4
Cho
Cr
NA
A
ppm
4.0 3.5 3.0 2.5 2.0 1.5 1.0 0.5
-800
-400
0
400
800
Sig
nal (
MR
Uni
ts)
Voxel # 25, S48.4
Cho C
r
NA
A
ppm4.0 3.5 3.0 2.5 2.0 1.5 1.0 0.5
-1000
-500
0
500
1000
1500
Sig
nal (
MR
Uni
ts)
Voxel # 25, S48.4
Real Spectrum Baseline Anchor Points
ppm
Vox# Cho Cr NAA24 80.8284 67.6039 83.806725 72.835 60.201 78.3303
Metabolite Ratios by Gaussian function
4.0 3.5 3.0 2.5 2.0 1.5 1.0 0.5
-400
0
400
800
1200
Sig
nal (
MR
Uni
ts) Voxel # 26, S48.4
Baseline Real Spectrum Anchor Points
ppm4.0 3.5 3.0 2.5 2.0 1.5 1.0 0.5
-1500
-1000
-500
0
500
1000
1500
Sig
nal (
MR
Uni
ts)
Voxel # 26, S48.4
Cho
Cr
NA
A
ppm
4.0 3.5 3.0 2.5 2.0 1.5 1.0 0.5
0
4000
8000
12000
16000
Sig
nal (
MR
Uni
ts)
ppm
Real Spectrum Baseline Anchor Points
Voxel # 30, S48.4
4.0 3.5 3.0 2.5 2.0 1.5 1.0 0.50
1000
2000
3000
4000
5000
6000
Sig
nal (
MR
Uni
ts)
Voxel # 30, S48.4
ppm
Cho Cr N
AA
Vox# Cho Cr NAA26 46.8174 45.9532 161.8730 42.7225 55.2936 76.0572
Metabolite Ratios by Gaussian function
4.0 3.5 3.0 2.5 2.0 1.5 1.0 0.5-3000
-2000
-1000
0
1000
2000
3000
4000
Sig
nal (
MR
Uni
ts)
Voxel # 31, S48.4
Real Spectrum Baseline Anchor Points
ppm4.0 3.5 3.0 2.5 2.0 1.5 1.0 0.5
-1000
-500
0
500
Sig
nal (
MR
Uni
ts) Voxel # 31, S48.4
Cho C
r
NA
A
ppm
4.0 3.5 3.0 2.5 2.0 1.5 1.0 0.5-1500
-1000
-500
0
500
1000
1500
2000
2500
Sig
nal (
MR
Uni
ts)
Voxel # 32, S48.4
Real Spectrum Baseline Anchor Points
ppm4.0 3.5 3.0 2.5 2.0 1.5 1.0 0.5
-1000
-800
-600
-400
-200
0
200
Sig
nal (
MR
Uni
ts)
Voxel # 32, S48.4
Cho C
r
NA
A
ppm
Vox# Cho Cr NAA31 66.9078 60.2342 93.427132 80.2909 67.089 97.621
Metabolite Ratios by Gaussian function
4.0 3.5 3.0 2.5 2.0 1.5 1.0 0.5-1000
-500
0
500
1000
1500
2000
Sig
nal (
MR
Uni
ts)
Voxel # 33, S48.4
Real Spectrum Baseline Anchor Points
ppm4.0 3.5 3.0 2.5 2.0 1.5 1.0 0.5
-1500
-1000
-500
0
500
Sig
nal (
MR
Uni
ts) Voxel # 33, S48.4
ppm
Cho C
r
NA
A
4.0 3.5 3.0 2.5 2.0 1.5 1.0 0.5-1000
0
1000
2000
3000
Sig
nal (
MR
Uni
ts)
Real Spectrum Baseline Anchor Points
Voxel # 38, S48.4
ppm4.0 3.5 3.0 2.5 2.0 1.5 1.0 0.5
0
250
500
750
1000
Sig
nal (
MR
Uni
ts)
Voxel # 38, S48.4
Cho
Cr
NA
A
ppm
Vox# Cho Cr NAA33 46.5804 46.9366 111.2338 31.2431 43.8876 81.9015
Metabolite Ratios by Gaussian function
4.0 3.5 3.0 2.5 2.0 1.5 1.0 0.5
0
1000
2000
3000
4000
5000
Sig
nal (
MR
Uni
ts)
Voxel # 40, S48.4
Real Spectrum Baseline Anchor Points
ppm4.0 3.5 3.0 2.5 2.0 1.5 1.0 0.5
-200
0
200
400
600
Sig
nal (
MR
Uni
ts)
Voxel # 40, S48.4
Cho
Cr NA
A
ppm
4.0 3.5 3.0 2.5 2.0 1.5 1.0 0.5
0
4000
8000
12000
16000
Sig
nal (
MR
Uni
ts)
Voxel # 41, S48.4
Real Spectrum Baseline Anchor Points
ppm4.0 3.5 3.0 2.5 2.0 1.5 1.0 0.5
0
250
500
Sig
nal (
MR
Uni
ts)
Cho C
r
NA
A
Voxel # 41, S48.4
ppm
Vox# Cho Cr NAA40 18.3688 26.334 54.410641 7.88215 15.7238 38.5249
Conclusion
7 14 21 28 35 42 490
60
120
0
2
4
Cho Cr NAA
NAA/Cr Cho/NAA Cho/Cr
Met
. Con
.R
atio
s
Voxel Index
Descriptive Statistics on Exam 4633
Exam5181 N total MeanStandard Deviation Sum Minimum Median Maximum
Cho 14 47.87807 22.42504 670.293 7.88215 44.65145 80.8284
Cr 14 48.56296 14.50601 679.8814 15.7238 49.5453 67.6039
NAA 14 83.23476 30.0691 1165.287 38.5249 80.63275 161.87
NAA/Cr 14 1.79737 0.63692 25.16313 1.16593 1.53785 3.5225
Cho/NAA 14 0.5856 0.26215 8.19838 0.2046 0.50554 0.96446
Cho/Cr 14 0.93595 0.24397 13.10335 0.50129 1.00561 1.21267
# on Exam 4633
Voxel # Cho Cr NAA NAA/Cr Cho/NAA Cho/Cr
10 41.2846 39.1755 45.6759 1.16593 0.90386 1.053837
16 30.6817 48.0501 73.2585 1.524627 0.418814 0.638536
17 63.4934 52.3584 79.364 1.515784 0.800028 1.212669
23 40.3568 51.0405 89.809 1.759563 0.449363 0.790682
24 80.8284 67.6039 83.8067 1.239673 0.964462 1.195617
25 72.835 60.201 78.3303 1.301146 0.929845 1.209864
26 46.8174 45.9532 161.87 3.522497 0.289228 1.018806
30 42.7225 55.2936 76.0572 1.375515 0.561715 0.772648
31 66.9078 60.2342 93.4271 1.551064 0.71615 1.110794
32 80.2909 67.089 97.621 1.455097 0.822476 1.196782
33 46.5804 46.9366 111.23 2.369792 0.418776 0.992411
38 31.2431 43.8876 81.9015 1.866165 0.381472 0.711889
40 18.3688 26.334 54.4106 2.066173 0.337596 0.697532
41 7.88215 15.7238 38.5249 2.450101 0.204599 0.501288
