16
Bimonthly Meeting on March 13, 2009 Amarjeet Bhullar MRS on Exam 5181

Bimonthly Meeting on March 13, 2009 Amarjeet Bhullar MRS on Exam 5181

  • View
    218

  • Download
    0

Embed Size (px)

Citation preview

Bimonthly Meeting on March 13, 2009

Amarjeet Bhullar

MRS on Exam 5181

NLB_24Feb_2009, Exam 5181, S40.5

Metabolite Ratios by Gaussian function

4.0 3.5 3.0 2.5 2.0 1.5 1.0 0.5

0

2000

4000

6000

8000

Baseline Real Spectrum Anchor Points

Sig

nal

(M

R U

nit

s)

ppm

Voxel # 16, S40.5

4.0 3.5 3.0 2.5 2.0 1.5 1.0 0.5

0

1000

2000

3000

Real Spectrum Baseline Anchor Points

ppm

Sig

nal

(M

R U

nit

s)

Voxel # 17, S40.5

4.0 3.5 3.0 2.5 2.0 1.5 1.0 0.5

0

1000

2000

3000

Sig

nal

(M

R U

nit

s)

Voxel # 17, S40.5

Cr

Cho

NA

A

ppm

4.0 3.5 3.0 2.5 2.0 1.5 1.0 0.5

0

1000

2000

3000

4000

ppm

Sig

nal

(M

R U

nit

s)

Cho Cr

NA

A

Voxel # 16, S40.5

Metabolite Ratios by Gaussian function

4.0 3.5 3.0 2.5 2.0 1.5 1.0 0.5

-1500

-1000

-500

0

500

1000

ppm

Sig

nal

(M

R U

nit

s)

Cho

Cr

NA

A

Voxel # 18, S40.5

4.0 3.5 3.0 2.5 2.0 1.5 1.0 0.5

-1000

0

1000

2000

Baseline Real Spectrum Anchor Points

Voxel # 18, S40.5

Sig

nal

(M

R U

nit

s)

ppm

4.0 3.5 3.0 2.5 2.0 1.5 1.0 0.5-400

0

400

800

1200

1600

Sig

nal

(M

R U

nit

s)

Voxel # 19, S40.5

Cho

Cr

NA

A

ppm4.0 3.5 3.0 2.5 2.0 1.5 1.0 0.5

-1000

-500

0

500

1000

1500

Real Spectrum Baseline Anchor Points

Sig

nal

(M

R U

nit

s)

Voxel # 19, S40.5

ppm

Metabolite Ratios by Gaussian function

4.0 3.5 3.0 2.5 2.0 1.5 1.0 0.5

0

500

1000

1500

2000

ppm

Sig

nal

(M

R U

nit

s) Real Spectrum Baseline Anchor Points

Voxel # 20, S40.5

4.0 3.5 3.0 2.5 2.0 1.5 1.0 0.5-200

0

200

400

600

800

1000

Sig

nal

(M

R U

nit

s)

Voxel # 20, S40.5

Cho C

r

NA

A

ppm

4.0 3.5 3.0 2.5 2.0 1.5 1.0 0.5

0

1000

2000

3000

4000

5000

Sig

nal

(M

R U

nit

s)

ppm

Real Spectrum Baseline Anchor Points

Voxel # 23, S40.5

4.0 3.5 3.0 2.5 2.0 1.5 1.0 0.5

0

1000

2000

3000

4000

Sig

nal

(M

R U

nit

s)

Voxel # 23, S40.5

Cho

Cr

NA

A

ppm

Metabolite Ratios by Gaussian function

4.0 3.5 3.0 2.5 2.0 1.5 1.0 0.5

-1000

0

1000

2000

ppm

Sig

nal

(M

R U

nit

s)

Real Spectrum Baseline Anchor Points

Voxel # 24, S40.5

4.0 3.5 3.0 2.5 2.0 1.5 1.0 0.5

0

1000

2000

3000

Sig

nal

(M

R U

nit

s)

Voxel # 24, S40.5

NA

A

ppm

Cho

Cr

4.0 3.5 3.0 2.5 2.0 1.5 1.0 0.5-1000

-500

0

500

1000

1500

2000

Sig

nal

(M

R U

nit

s)

Real Spectrum Baseline Anchor Points

Voxel # 25, S40.5

ppm4.0 3.5 3.0 2.5 2.0 1.5 1.0 0.5

0

1000

2000

3000

Sig

nal

(M

R U

nit

s)

Voxel # 25, S40.5

Cho

Cr

NA

A

ppm

Metabolite Ratios by Gaussian function

4.0 3.5 3.0 2.5 2.0 1.5 1.0 0.5

0

1000

2000

3000

Sig

nal

(M

R U

nit

s)

ppm

Real Spectrum Baseline Anchor Points

Voxel # 26, S40.5

4.0 3.5 3.0 2.5 2.0 1.5 1.0 0.5

0

1000

2000

3000

Sig

nal

(M

R U

nit

s)

Voxel # 26, S40.5

Cho

Cr

NA

A

ppm

4.0 3.5 3.0 2.5 2.0 1.5 1.0 0.5-500

0

500

1000

1500

2000

Sig

nal

(M

R U

nit

s) Real Spectrum Baseline Anchor Points

Voxel # 27, S40.5

ppm4.0 3.5 3.0 2.5 2.0 1.5 1.0 0.5

-500

0

500

1000

1500

2000

Sig

nal

(M

R U

nit

s)

Voxel # 27, S40.5

Cho Cr

NA

A

ppm

Metabolite Ratios by Gaussian function

4.0 3.5 3.0 2.5 2.0 1.5 1.0 0.5

0

2000

4000

6000

ppm

Sig

nal

(M

R U

nit

s)

Real Spectrum Baseline Anchor Points

Voxel # 30, S40.5

4.0 3.5 3.0 2.5 2.0 1.5 1.0 0.5-500

0

500

1000

1500

2000

2500

Sig

nal

(M

R U

nit

s)

Voxel # 30, S40.5

Cho Cr

NA

A

ppm

4.0 3.5 3.0 2.5 2.0 1.5 1.0 0.5

-500

0

500

1000

1500

2000

2500

Sig

nal

(M

R U

nit

s)

Real Spectrum Baseline Anchor Points

Voxel # 31, S40.5

ppm4.0 3.5 3.0 2.5 2.0 1.5 1.0 0.5

0

500

1000

1500

2000

2500

3000

Sig

nal

(M

R U

nit

s)

Voxel # 31, S40.5

ppm

Cho

Cr

NA

A

Metabolite Ratios by Gaussian function

4.0 3.5 3.0 2.5 2.0 1.5 1.0 0.5

0

1000

2000

3000

Sig

nal

(M

R U

nit

s)

Real Spectrum Baseline Anchor Points

Voxel # 32, S40.5

ppm4.0 3.5 3.0 2.5 2.0 1.5 1.0 0.5

0

1000

2000

3000

4000

Sig

nal

(M

R U

nit

s)

Voxel # 32, S40.5

ppm

Cho

Cr

NA

A

4.0 3.5 3.0 2.5 2.0 1.5 1.0 0.5

0

1000

2000

3000

4000

Sig

nal

(M

R U

nit

s)

Voxel # 33, S40.5 Real Spectrum Baseline Anchor Points

ppm4.0 3.5 3.0 2.5 2.0 1.5 1.0 0.5

0

1000

2000

3000

4000

Sig

nal

(M

R U

nit

s)

Voxel # 33, S40.5

Cho

Cr

NA

A

ppm

Metabolite Ratios by Gaussian function

4.0 3.5 3.0 2.5 2.0 1.5 1.0 0.5

0

500

1000

1500

2000

Sig

nal

(M

R U

nit

s)

Voxel # 34, S40.5 Real Spectrum Baseline Anchor Points

ppm4.0 3.5 3.0 2.5 2.0 1.5 1.0 0.5

0

500

1000

1500

2000

Sig

nal

(M

R U

nit

s)

Voxel # 34, S40.5

Cho

Cr

NA

A

ppm

4.0 3.5 3.0 2.5 2.0 1.5 1.0 0.5

0

4000

8000

12000

Sig

nal

(M

R U

nit

s)

Voxel # 37, S40.5

Real Spectrum Baseline Anchor Points

ppm4.0 3.5 3.0 2.5 2.0 1.5 1.0 0.5

0

2000

4000

6000

8000

Sig

nal

(M

R U

nit

s)

Voxel # 37, S40.5

Cho

Cr N

AA

ppm

Metabolite Ratios by Gaussian function

4.0 3.5 3.0 2.5 2.0 1.5 1.0 0.5

0

1000

2000

3000

Sig

nal

(M

R U

nit

s)

Voxel # 38, S40.5

Real Spectrum Baseline Anchor Points

ppm4.0 3.5 3.0 2.5 2.0 1.5 1.0 0.5

-500

0

500

1000

1500

2000

2500

ppm

Sig

nal

(M

R U

nit

s)

Voxel # 38, S40.5

Cho Cr

NA

A

4.0 3.5 3.0 2.5 2.0 1.5 1.0 0.5-2000

-1000

0

1000

2000

3000

Sig

nal

(M

R U

nit

s)

Voxel # 39, S40.5

Real Spectrum Baseline Anchor Points

ppm4.0 3.5 3.0 2.5 2.0 1.5 1.0 0.5

-1000

0

1000

2000

3000

Sig

nal

(M

R U

nit

s)

Voxel # 39, S40.5

Cho

Cr

NA

A

ppm

Metabolite Ratios by Gaussian function

4.0 3.5 3.0 2.5 2.0 1.5 1.0 0.5

0

1000

2000

3000

Sig

nal

(M

R U

nit

s)

Voxel # 40, S40.5

ppm

Real Spectrum Baseline Anchor Points

4.0 3.5 3.0 2.5 2.0 1.5 1.0 0.5

0

500

1000

1500

2000

2500

Sig

nal

(M

R U

nit

s)

Voxel # 40, S40.5

Cho Cr

NA

A

ppm

4.0 3.5 3.0 2.5 2.0 1.5 1.0 0.5

0

1000

2000

3000

4000

Sig

nal

(M

R U

nit

s)

Voxel # 41, S40.5

Real Spectrum Baseline Anchor Points

ppm4.0 3.5 3.0 2.5 2.0 1.5 1.0 0.5

0

500

1000

1500

2000

Sig

nal

(M

R U

nit

s)

Voxel # 41, S40.5

Cho C

r

NA

A

ppm

Conclusion

15 20 25 30 35 40 450

100

200

300

400

500 Cho Cr NAA

Met

abol

ite

Con

.

Voxel Index10 20 30 400

5

10

Met

abol

ite

Rat

ios NAA/Cr

Cho/NAA Cho/Cr

Voxel Index

Conclusion

7 14 21 28 35 42 490

250M

et. C

on.

Rat

ios

NAA/Cr Cho/NAA Cho/Cr

Cho Cr NAA

Voxel Index

0

5

10

Descriptive Statistics on Exam 5181

Exam5181 N total Mean Standard Deviation Sum Minimum Median Maximum

Cho 20 92.19968 45.06231 1843.994 26.3443 79.92885 173.846

Cr 20 82.67384 38.67509 1653.477 26.6278 83.4441 144.951

NAA 20 198.7451 91.28516 3974.902 71.7208 177.362 455.092

NAA/Cr 20 2.97148 2.2592 59.42959 1.43855 1.84054 10.17202

Cho/NAA 20 0.49232 0.17744 9.84641 0.09125 0.52672 0.80998

Cho/Cr 20 1.16189 0.43303 23.23784 0.73672 1.04297 2.59402

# on Exam 5181

Cho Cr NAA NAA/Cr Cho/NAA Cho/Cr

16 41.5259 44.7396 455.092 10.17202 0.091247 0.928169

17 131.125 109.804 235.514 2.144858 0.556761 1.194173

18 80.1995 30.9171 181.974 5.885869 0.44072 2.594018

19 55.2244 26.6278 166.746 6.262102 0.331189 2.073938

20 26.3443 35.7591 109.101 3.051 0.241467 0.736716

23 77.6021 67.0489 366.051 5.459463 0.211998 1.157396

24 143.823 122.52 217.628 1.776265 0.660866 1.173874

25 173.846 130.519 214.63 1.644435 0.80998 1.331959

26 161.217 137.851 258.233 1.873276 0.624308 1.169502

27 50.1289 51.1685 166.198 3.248053 0.301622 0.979683

30 78.0842 86.7197 156.773 1.807813 0.498072 0.900421

31 125.804 125.804 180.975 1.438547 0.695146 1

32 154.535 144.951 260.726 1.798718 0.59271 1.066119

33 125.872 112.627 250.988 2.228489 0.501506 1.117601

34 64.806 58.4722 126.897 2.170211 0.510698 1.108322

37 47.9615 52.2592 87.939 1.682747 0.545395 0.917762

38 79.6582 80.1685 130.947 1.633397 0.608324 0.993635

39 102.485 100.493 173.749 1.728966 0.589845 1.019822

40 88.4783 91.1669 163.02 1.788149 0.542745 0.970509

41 35.2733 43.8603 71.7208 1.63521 0.491814 0.804219