A Case Study Of A Man With Leukemia

A Chromosomal Translocation is Discovered

PDGFR-beta null mutants are embryonically lethal

PDGFR alpha and beta have different downstream consequences

AngiogenesisLymphocytesMetabolism

The PDGF receptor can activate many Different Pathways

The ETV6-PDGFRB fusion causes constitutive dimerization

Chronic Myelomonocytic Leukemia (CMML)Is a Cancer of the Monocytes

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