7 Pharmacokinetics-Erna Kristin-Pharmacology and Toxicology (2015)

Embed Size (px)

Citation preview

  • 7/26/2019 7 Pharmacokinetics-Erna Kristin-Pharmacology and Toxicology (2015)

    1/23

    Erna Kristin

    Department ofPharmacology &Toxicology

  • 7/26/2019 7 Pharmacokinetics-Erna Kristin-Pharmacology and Toxicology (2015)

    2/23

    Pharmacokinetics

  • 7/26/2019 7 Pharmacokinetics-Erna Kristin-Pharmacology and Toxicology (2015)

    3/23

    Drug AdministrationDosage Forms for OralFrom Application to Distribution

    Drug EliminationPharmacokineticsDrug Concentration in the Body as a

    Function of Time.

    Objectives

  • 7/26/2019 7 Pharmacokinetics-Erna Kristin-Pharmacology and Toxicology (2015)

    4/23

  • 7/26/2019 7 Pharmacokinetics-Erna Kristin-Pharmacology and Toxicology (2015)

    5/23

    Pharmacology

    Pharmacology is

    the study of drugs

    and the effects

    they have on the

    body

  • 7/26/2019 7 Pharmacokinetics-Erna Kristin-Pharmacology and Toxicology (2015)

    6/23

    Pharmacokinetics

    The activity of drugs in the body

    over a period of time, including the

    processes by which drugs are

    absorbed, distributed in the body,

    localized in the tissues, and

    excreted.

  • 7/26/2019 7 Pharmacokinetics-Erna Kristin-Pharmacology and Toxicology (2015)

    7/23

  • 7/26/2019 7 Pharmacokinetics-Erna Kristin-Pharmacology and Toxicology (2015)

    8/23

  • 7/26/2019 7 Pharmacokinetics-Erna Kristin-Pharmacology and Toxicology (2015)

    9/23

  • 7/26/2019 7 Pharmacokinetics-Erna Kristin-Pharmacology and Toxicology (2015)

    10/23

  • 7/26/2019 7 Pharmacokinetics-Erna Kristin-Pharmacology and Toxicology (2015)

    11/23

  • 7/26/2019 7 Pharmacokinetics-Erna Kristin-Pharmacology and Toxicology (2015)

    12/23

  • 7/26/2019 7 Pharmacokinetics-Erna Kristin-Pharmacology and Toxicology (2015)

    13/23

  • 7/26/2019 7 Pharmacokinetics-Erna Kristin-Pharmacology and Toxicology (2015)

    14/23

  • 7/26/2019 7 Pharmacokinetics-Erna Kristin-Pharmacology and Toxicology (2015)

    15/23

  • 7/26/2019 7 Pharmacokinetics-Erna Kristin-Pharmacology and Toxicology (2015)

    16/23

  • 7/26/2019 7 Pharmacokinetics-Erna Kristin-Pharmacology and Toxicology (2015)

    17/23

    Cmax

    Tmax

    Min toxic conc

    Min therap conc

  • 7/26/2019 7 Pharmacokinetics-Erna Kristin-Pharmacology and Toxicology (2015)

    18/23

    Half life: the

    amount of

    time unit

    time) it takes

    for half of drug

    concentration

  • 7/26/2019 7 Pharmacokinetics-Erna Kristin-Pharmacology and Toxicology (2015)

    19/23

  • 7/26/2019 7 Pharmacokinetics-Erna Kristin-Pharmacology and Toxicology (2015)

    20/23

  • 7/26/2019 7 Pharmacokinetics-Erna Kristin-Pharmacology and Toxicology (2015)

    21/23

  • 7/26/2019 7 Pharmacokinetics-Erna Kristin-Pharmacology and Toxicology (2015)

    22/23

  • 7/26/2019 7 Pharmacokinetics-Erna Kristin-Pharmacology and Toxicology (2015)

    23/23