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22-24 April 1985 PERTUSSIS, Potsdam, GDR. POSTPONED In view of the recently announced 4th International Symposium on Pertussis, sponsored by the International Association of Biological Standardization and the World Health Organization, to be held at the WHO, Geneva, September 25-27 1984, the Organising Committee and the FEMS Executive have been obliged to postpone the planned Symposium in the GDR. I t wil l be held in the GDR at a date to be announced.

17-20 June 1985 MOLECULAR BIOLOGY OF MICROBIAL PATHOGENICITY: ~ ADHESION, INVASION AND RECEPTORS, Ume~, Sweden. organised by: S.Normark, B.E.Uhlin and H.Wolf-Watz on behalf of the Swedish Society for Microbiology and the University of UmeA. Speakers wi l l include: M.So (USA), K-A. Karlsson (Sweden), S.Svensson (Sweden), T.Korhonen (Finland), F.Mooi (Netherlands), F. de Graaf (Netherlands), P.Klemm (Denmark). The emphasis wil l be on the interaction of microorganisms and their products with host cells at the molecular level. Presentations (20-40 minutes) by invited speakers wil l include: A. Bacterial Adhesins: 1. Adhesins as virulence factors. 2. Gene organisation and regulation. 3. Structure and function of gene products encoded by adhesin gene clusters. 4. Pil i adhesins as antigens, antigenic variation. 5. Non-pili adhesins. 6. Evolution and epidemiology of adhesins. 7. Adhesins as potential vaccines. B. Invasive Bacteria: 1. Genetic determinants of invasive bacteria. 2. Surface structures involved in invasion. C. Receptors for Microbial Adhesins and Toxins: 1. Identification and structure determination. 2. Natural and synthetic receptor analogues. 3. Adhesin-receptor interactions. 4. Possible use of receptor analogues in prophylaxis and therapy. Contributed papers wi l l be in the form of poster sessions. Round Table discussions wil l be organised. Number of participants is restricted to 100. Fee: $400 (includes meals and shared room). Applicants should indicate areas of research which just i fy their consideration as participants. Students should enclose a letter of recommendation. Applications must be submitted before January 31 1985. Contact: S ~ r k ~ o-61~obiology, University of Ume~, S-901UMEA, ~eden. Tel: 090-10-10-00

24-26 June, 1985 MOLECULAR ORGANIZATION OF POSITIVE-STRAND RNA VIRUSES, Cambridge, England. organised by: D.J.Rowlands (Wellcome Biotechnolocty Ltd.), M.A.Mayo. (Scottish Crop Research Institute) and B.W.J.Mahy (Animal Virus Research Institute) on behalf of the Virus Group of the Society for General Microbiology. The meeting wil l be held at Churchill College, Cambridge. Invited speakers wil l discuss genome organization and function in symposia on each of the f i r s t two mornings, and the functional organization of virus particles in a symposium on the final morning. Sessions for offered paper presentations and workshops wil l be held in the afternoons. The topics to be covered wil l include: Translation mechanisms in picornaviruses (Palmenberg, Wisconsin), translation of monopartite genomes of plant viruses (Haenni, Paris), coronavirus genomes (Sidde11, Wurzburg), comovirus genome strategy (van Kammen, Wageningen), translation and replication of togovirus RNA (Strauss, Pasadena), picornavirus replication (Wimmer, Stonybrook), tobacco mosaic virus molecular architecture (Butler, Cambridge) and picornavirus proteins and antigenicity (Minor, London). Contact: Dr.D.J.Rowlands, Wellcome Biotechnology Ltd., Ash Road, Pirbright, Woking Surrey, GU24 ONQ, U.K.