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1 3 >=39;< ;4<=480 (;7<98 $;0<08=482 >=39; ,;/,?0 & 466 (84?0;<4=B 91 &,<5,=.30@,8 $;47,;B >=39; 9>=39;<< ;4<=480 (;7<98 (84?0;<4=B 91 &,<5,=.30@,8 !%#"&%"! /;08,6 48<>114.408.B 4< , /4<9;/0; 91 =30 ,/;08,6 26,8/< @30;0 =30B /9 89= :;9/>.0 089>23 91 .0;=,48 39;7980< 7,486B .9;=4<96 ,8/ ,6/9<=0;980 !,8,20708= 91 :,=408=< @4=3 ,/;08,6 48<>114.408.B :;0<08=482 19; <>;20;B 48 ;02,;/< =9 <=0;94/ <>::60708=,=498 ;07,48< >8.60,; 982084=,6 ,/;08,6 3B:0;:6,<4, 980 19;7 91 ,/;08,6 48<>114.408.B 4< , /4<9;/0; 48?96?482 , /014.408.B 91 ,8 08CB70 48?96?0/ 48 =30 <B8=30<4< 91 .9;=4<96 ,6/9<=0;980 9; -9=3 >;;08= 2>4/06480< ,;0 .60,; =3,= 3423 /9<0 <=0;94/< ,;0 ;0.97708/0/ 19; .346/;08 @4=3 >8/0;29482 ,80<=30<4, 423 /9<0 <=0;94/< 3,?0 :9=08=4,6 ;4<5< <>.3 ,< -;,/B.,;/4, 3B:9=08<498 ,8/ ,<B<=960 48.;0,<0/ ;4<5 91 4810.=498 -699/ 26>.9<0 /4<9;/0;< 64?0; 2,<=;948=0<=48,6 0110.=< ,8/ :<B.34,=;4. <B8/;970< 4?08 =30 ;4<5< 4/08=4140/ 4= 4< 47:9;=,8= =9 0A,7480 41 .>;;08= ;0.97708/,=498< ;0160.= .6484.,6 :;,.=4.0 48 :;9?4/482 9:=47,6 .,;0 19; :,=408=< %"$ 9.,6 ;0<0,;.3 0=34.< -9,;/ ,::;9?,6 @,< 9-=,480/ :;49; =9 <=>/B .97708.0708= .;9<<<0.=498,6 <>;?0B @,< /4<=;4->=0/ 19669@482 :;0=0<=482 ,8/ :469==0<=482 8?4=,=498 =9 :,;=4.4:,=0 48 =30 <>;?0B @,< /4<=;4->=0/ ?4, =30 ,8,/4,8 $0/4,=;4. 80<=30<4, &9.40=B 707-0;<D 07,46 64<= '30 484=4,6 07,46 48?4=,=498 @,< 19669@0/ @4=3 =@9 ,//4=498,6 48?4=,=498< =9 .97:60=0 =30 <>;?0B %0<:98<0< @0;0 ,8,6BC0/ ><482 <=,8/,;/ =,->6,=498< $&%$ 91 ;0<:98/08=< @9>6/ 89= :;9?4/0 <=;0<</9<0 <=0;94/< 19; , .B<=9<.9:B ,8/ @9>6/ 89= /9 <9 19; , 6,:,;9=97B /0<:4=0 =30 8/9.;480 &9.40=B 6484.,6 >4/06480< 98 &00 ',-60 $&$$"! #>; ;0<>6=< /0798<=;,=0 ?,;4,=498 48 .6484.,6 ,80<=30=4. :;,.=4.0 ;02,;/482 <=;0<< /9<0 <=0;94/< 48 .346/;08 @4=3 >8/0;29482 ,80<=30<4, ?08 @308 2>4/06480< ,;0 :;9?4/0/ 7,8B ;0<:98/08=< 48/4.,=0/ =30B @9>6/ 89= 19669@ =307 #>; /,=, ,6<9 34236423= =3,= =30 /0.4<498 =9 :;9?4/0 <=;0<< /9<0 <=0;94/< 4< ;06,=0/ =9 =30 :;9:9<0/ :;9.0/>;0 48,66B 24?08 =30 <428414.,8= ?,;4,=498 91 :;,.=4.0 , 800/ 19; 1>=>;0 ;0<0,;.3 4< 4/08=4140/ @4=3 ,8 0B0 =9 .3,820 .>;;08= :;,.=4.0 ;0.97708/,=498< Can J Anesth/J Can Anesth (2017) 63:S1–S357 DOI 10.1007/s12630-016-0810-z © Canadian Anesthesiologists’ Society 2017

138022 - peri-operative steroid supplementation for adrenal

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Can J Anesth/J Can Anesth (2017) 63:S1–S357DOI 10.1007/s12630-016-0810-z

© Canadian Anesthesiologists’ Society 2017

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Evaluation of publication bias in preclinical studies of anesthetic neuroprotection in stroke using Duval and Tweedie's trim and fill method. Individual funnel plots are presented for all studies (A), permanent ischemia studies (B), transient ischemia preconditioning (C) and transient ischemia postconditioning (D).

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Conclusion: The safety and efficacy of TAVI and MitraClip have made therapeutic options for high risk or inoperable aptients. Following careful patient selection and repeated evaluation by an experienced multidisciplinary team, our patient underwent both interventions at the same time with good results. References: 1. Alghamdi et al. Card Surg 2010;25:182-7. TEE 3D image post procedures

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J Emerg Med 2015 Oct 20Qual Saf Health Care 2010 Oct;19 Suppl 3:i53-6

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