Cleansing Soap

Plant Stem CellNatural Soap

(Yew Tree / Wild Ginseng / Tomato)

ContentsContents

High-density natural plant Stem Cell Broth is effective on all skin typesBringing great improvement to your skin

Part 1. Product Development Background

- Skin Worries

- Stem cell Cosmetics

- Plant stem cell

Part 3. Wild Ginseng PSC

Cleansing Bar

- Troubled skin

- Product Features

- Target Market

Part 2. Yew PSC Cleansing Bar

- Dry Skin

- Product Features

- Target Market

Part 4. Tomato PSC Cleansing

Bar

- Loose Skin

- Product Features

- Target Market

Product Development BackgroundProduct Development Background

Skin Worries

Stem Cell Cleansing Bar

Plant Stem Cell

According to the ‘Global Beauty Survey’ where ten thousand women(12~59 years

old) from 12 different countries participated,

Is there a way to prevent aging of cells in

the skin?

The biggest skin worries of women today

1st Acnes

Others

3rd Skin Color

2nd Wrinkles and Aging

60%40%

22%

21%

21%

Pro inflammatory of Cuticle cell and oil glands

Collagen and elastin aging

Inactive moisture supply on skin

Stem Cell Cleansing BarStem Cell Cleansing BarSkin Worries

Plant Stem Cell


What is Stem Cell?

What is Stem Cell?: Unspecialized cell which can differentiate into various cells

Stem Cell Cleansing Bar?

What is Stem Cell Cleansing Bar?: Stem cell cleansing bar may be defined as a soap product made

from ingredients obtained during a research of the stem cells; the in-

gredients are utilized directly and/or indirectly.

Ddobyul® = The True Plant Stem Cell

▲ Ddobyul® ▲ normal plant cell

VS Unlike normal plant cells which have one vacuole, Ddobyul

® consists of numerous small vacuoles in order to overcome pressure and stress..

Plant Stem CellPlant Stem Cell

World’s first isolated/cultured plant stem cell,, Ddobyul®

Ddobyul® is the world’s first “plant stem cell”, an origin of a meristem, isolated and cultured by UNHWA’s tech-nology. It is an undifferentiated “immortal cell,’ with a power to live eternally. Through a joint research with Edinburgh Univer-

sity in England, we could identify that Ddobyul ® is clearly different from an artifi-cially dedifferentiated Callus cell.

Also according to studies, Ddobyul ® extract was proven to have a powerful anti-ag-ing substances to protect collagen, maintain skin elasticity, and preventing wrinkles, even better than retinoic acid, which was known for anti-aging ability up until now.

Plant Stem Cell


Skin Worries

UNHWA’s Research Partners

Immune stimulation efficacy of ginseng stem cell patent application 10-2010-0016303

Anti-aging, anti-oxidant efficacy of ginseng stem cell patent application 10-2009-0052340

Isolation and culture of plant stem cell patent application 10-2007-7030252

Ginseng stem cell listed on INCI 2-04-2008-7972

Ginseng stem cell culture media listed on INCI 2-03-2008-7672

Identification of Plant Stem Cell

Skin Efficacy Test Jeonbuk University/ Jeonju Univer-sity/ Kyoung Hee University

Plant Stem CellPlant Stem Cell

University of EdingurghDepartment of Life Sci-

ences, POSTECHInha University

Bioinformatics and Molecular Design Cen-ter, Yonsei University

Plant Stem Cell


Skin Worries

Natural Cleansing Bar

Natural Cleansing Bars use essential oils instead of synthetic fragrances and natural plant-based ingredients are used with-out preservatives, hardeners and surfactants. It is an all-natu-ral handmade cleanser bar made without any chemicals.

Basic CharacteristicsOf Natural Soap

No Artificial coloringLead, arsenic, mercury

Alcohol FreeHypoallergenic, water evaporation preventatives

Paraben FreeNon-toxic, natural preservatives

No Mineral OilContains 5 mineral nutrients

Lower pH than othersAlkalescense

Bio-FriendlyAll-Natural Formulation

Handmade90% of manufacturing process

Highly concentrated essencesNatural ingredients added

No synthetic preservativesSkin hypoallergenics

Fragrance FreeNatural additives

Regular Soap vs. Natural Soap

Regular Soap Natural Soap

Basic Ingredi-ents

Cheap animal oil or based oils 100% Natural plant-based oils

Chemical Addi-tives

Synthetic surfactants, preservatives, fragrances, artificial coloring,

EDTA, hardeners, etc.None added

Manufacturing Pressed out through molds at the fac-tory

Hand made

Cleansing Ef-fect

Washes away skins nutrients and ap-propriate sebum that should remain

on the skins surface

Sebum and impurities, Skin nutrients and hydration.

Moisturizing Ef-fect

Low moisturization through glycerin separation

Excellent moisturizing effect through large amounts of natural

glycerin

Color, Scent Artificial fragrances, artificial coloring

Natural aromatic essentials and natural coloring

(Paprika, tomatoes and other natu-ral plants and fruits)

Effects on Skin Not for use on sensitive skinCan be used for sensitive skin

types like:infants, eczema, acne and aging

Environmental Pollution

Reason for environmental pollutionBio-friendly (carbon dioxide de-

composition)

Regular Soap vs. Natural Soap – Combustion Test

Even when lit with fire and cooled, it does not burn or change in color but remains clean and changes to liquid form! It is 100% natural formulation without any chemicals.

When lit with fire and cooled the chemicals burned and left a strong smell. It left black ashes and combustion residues.

Regular Soap vs. Natural Soap – Combustion Test

Even when lit with fire and cooled, it does not burn or change in color but remains clean and changes to liquid form! It is 100% natural formulation without any chemicals.

When lit with fire and cooled the chemicals burned and left a strong smell. It left black ashes and combustion residues.

DDOBYUL COSMETICSPLANT STEM CELL SKIN SOLUTION

Yew Tree PSC Cleansing Bar

Yew Tree PSC Cleansing BarYew Tree PSC Cleansing BarTroubled Skin

Product Features

Target Market

Purification of germs

Horny layer treatments

Minimizing dermal stress

Inflammatory relief

Suppressing skin trouble

Sebum secretion control

Sebum & Moisture

balance control

Solutions to ‘Troubled Skin’

Increase of sebum secretionStress, inborn

Hyperkeratotic of poresExcessive epidermal growth on pore

Lack of proteolytic enzyme in horny layer

Inflammatory by germ growth Environmental pollution, wide pores, germs

Causes of Troubled Skin and solutions

Causes of Trouble?

Skin damage by UV Radiation

pH balance collapsed

Yew Tree PSC Cleansing BarYew Tree PSC Cleansing Bar

Concept of YewCleansing Bar

Yew Tree PSC Cleansing Bar relieves trouble caused by excessive

sebum and acne bacteria managing a pure and clear skin

Keratin Treatment & Pore Contraction

Sebum ControlPurification & In-flammatory relief

Tea Tree Oil

Glycerin

Yew Stem Cell

Broth

Camellia oil

Green Tea Extract

Lavender

Strong Anti-oxi-dant Activity

Sebum controlTrouble Solution

Suppress P.

Acne

Inflammatory

relief

Skin Relief

Keratin Treat-

ment

Pore Contrac-

tion

Moisturization

Troubled Skin

Product Features

Target Market

Efficacies of Yew tree – anti-cancer, anti-inflammatory activities

Components of Yew Tree

Alkaloids such as taxinine, ponasterone,

ecdysterone and taxol which has anti-can-

cer effects.

Taxol exists in leaves, stems, roots and seeds of the Yew tree and is developed into

pharmaceutical products which shows anti-cancer effects.

According to the NCI, it is highly effective on breast cancer and ovarian cancer. Also,

30% of lung cancer patients were improved after injection, and 48% of patients’ tumors

were reduced.

What is taxol? Prevents growth of cancer cells in the metaphase without damaging DNA molecules or DNA and RNA synthesis of cancer cells.

Troubled Skin

Product Features

Target MarketYew Tree PSC Cleansing BarYew Tree PSC Cleansing Bar

LPS (Lipopolysaccharides) was applied in order to induce inflammation of human dermal fibroblasts. After methanol extract of yew Ddobyul is applied, manifestation of cytokine is suppressed, hence verifying Ddobyul’s anti-inflammation capability.

Anti-Inflammatory Activ-ity

Efficacies of Yew Plant Stem Cell

• Yew stem cells normally has anti-oxidation abilities in order to bear oxidative stress. Anti-oxidation in yew Ddobyul was verified to be 33.6 times greater than common cultured cells(catalase activity).

• Strong anti-oxidant activity eliminates excess reactive oxy-gen accumulated within a living organism, enabling the maintenance of health and preventing diseases

Strong Anti-Oxidation Activity

H2O

O2

H2O2

peroxide

Normal cell Ddobyul

Water

oxygen

- Anti-oxidant efficacy test of Yew Ddobyul -

Troubled Skin

Product Features


Troubled Skin

Product Features

Target Market

Tea tree oil showed much stronger antibacterial activity when compared to the 95% ethanol extract. For a long time, tea tree leaves have been used and known for strong sterilization, disinfection, purification, and skin inflammation. Tea tree leaf oil can be used for anti-inflammation and soothing of infected skin such as acne, zits and athlete’s foot.

More effective Applications

Tea Tree – Skin soothing, Sebum control, anti-inflammatory

Catechin contained in green tea extract recovers natural defensive power of the skin from skin damage due to external and internal stress.Also, there are plentiful tannin acid which is highly effective in skin astringent effect and moisture absorption. Moreover, green tea has sterilizing power which help to keep your skin clean.Vitamin A and B is effective in treating troubles because it keeps the skin smooth and revitalizes rough skin.

Green Tea extract – Recovering skin defensive power, astringent effect


Features of Yew Cleansing Bar

Stage 1

Stage 2

Stage 3

Stage 4

Others

Preventing trouble through sebum control

Suppressing acne bacteria through antibacterial & anti-inflammatory effect

Preventing further skin trouble through skin relief & pore contraction

Preventing acne scars

Comfortable application without stress

Immediate soothing effect

Moisturizing effect

Yew Stem Cell Broth Camellia Oil

Green tea Extract, Tea Tree Oil

Green tea Extract, Lavender

Yew Stem Cell Broth Green tea Extract, Camellia Oil

Troubled Skin

Product Features


Troubled Skin

Product Features

소구 대상

세안후 피부관리 step1!

세안 후 내 피부가 가장 처음 만나는 SUPER TONER! 피부에 남아있을 노폐물을

최종적으로 제거해주며 유연한 피부로 정돈합니

다 .

촉촉하고 영양감있는 토너

프레쉬한 시트러스향의 에센스 타입 토너로 건조한 피부에

최대한 영양과 수분을 보충하며 최대한 빨리 촉촉함을

부여해주는 실키한 마무리감의 스페셜 케어 토너 .

Target Market

Product DescriptionHigh quality beauty soap contains purified plant-based natural ingredients

that cause minimal irritation and has rich foaming cleansing power.

Features · Concept<Skin Trouble · Acne · Oily Skin>

Contains yew tree stem cell culture media and the tea tree leaf oil, green tea extract to make the skin clear and healthy.

Target Market• Persons with frequent skin problems• Customers that would like to resolve irregular skin texture• Customers with frequent acne and zits.

Key IngredientsYew tree stem cell culture media (2%) , purified water, glycerin, Triclosan,

tea tree oil, green tea extract, camellia oil, lavender powder and fragrance

Volume 100g

How to Use

1. Splash face with water and rub solid bar between palms until there is enough lather and gently massage face with soap.

2. Rinse off with warm water.



Wild Ginseng PSC Cleansing Bar

Dry Skin

Product Features

Target Market

Excessive UV

Exposure

Hot Baths

Lack of skin

care

Climate change

Excessive acne

tretment

Causes of Dryness

Characteristics of Dry Skin

Get rid of old horny

layer

From skin protection

Improve Moisture Retention

Improve Cutaneous Circulation

Because the metabolism is not well, dry skin results in dehydrated skin. Therefore, it is important to supply sufficient moisture and get rid of old horny layer.

Symptom1 Dehydrated Skin

When the temperature goes down and the air is arid, the skin gets dehydrated, and fine wrinkles appear. Fine wrinkles makes deeper wrinkles, so it is important to form protection on the skin.

Symptom2 Fine wrinkles

As people grow older, moisture retention reduces and the fibroblast does not fully function. Therefore, skin loses elasticity.

Symptom3 Lack of skin elasticity

Strenuous exercise greatly expands capillary vessel for the face to flush. It thins the horny layer reducing moisture retention. Cutaneous circulation is critical to prevent flushing.

Symptom4 Flushing

Solution

Wild Ginseng PSC Cleansing BarWild Ginseng PSC Cleansing Bar

Concept of Ginseng Cleansing Bar

Wild Ginseng PSC Cleansing Bar is an enriched

moistutrization soap improve moisture retention from deep

inside the skin to keep the skin smooth and clear

Strengthen Skin Elasticity

Improve Moisture Retention

Skin Revitalize & Protection

Seaweed powder

Olive oil

Ginseng Stem Cell Broth

Cacao powder

Red Ginseng

Extract

Fibroblast Proliferation

Skin Moisturization &

ReliefPrevent Collagen Damage

Promote Cell Generation

Revitalize skin

Anti-OxidantClear Skin

Remove Old Horny layer

Dry Skin

Product Features

Target MarketWild Ginseng PSC Cleansing BarWild Ginseng PSC Cleansing Bar

Efficacies of Ginseng – Immune Enhancement, Anti-Cancer

It is written in Dongui Bogam that ginseng is know to

tranquilize the mind and prevent sickness. When

taken for a long time, ginseng will help the person

live longer

Main Components of GinsengGinseng Saponins and GisenosideWater soluble components: acidic polysaccharide, protein, peptide, amino sugar, adenosine. Fat soluble components : Perill keton, phenolic components, polyacety-lene, alkaloidsOthers: water soluble vitamins, minerals

Ginseng Saponins is highly effective on patients with low immune competence occurred by chemother-

apy and ginseng prevents tumors to transfer into malignant tumors. Moreover, ginseng is known to pre-

vent recurrence of cancer after treatment and suppress cancer growth. Efficacies of ginseng has been

widely researched by Kim Byoung Soo, Yonsei University Cancer Center president, Professor Odashima in

Ginki University, Professor Hisayama and Murada from Japan.

According to the immune enhancement study conducted by Jo Gyu Hyuk, Jeon Nam University, reticu-

loendothelium system, which is in charge of immune system in cells, recovery could be observed after

giving ginseng saponins.

Ginseng is effective on immune enhancement, chemotherapy recovery, and

anti-cancer activities.

Dry Skin

Product Features


Anti-Aging effect of Ginseng Ddobyul

Active substances in the ginseng stem cell are composed of fine molecular particles which can pene-

trate cell walls. Through this, we can find out that it is composed of mixed compounds of water and fat

soluble elements. The active substances of the ginseng stem cell culture media is absorbed through oil

glands and horny layer

(proved through in-vitro experiments)

Restora-tion of UV Damaged Skin

Elimina-tion of Reactive Oxygen

Suppres-sion of Natural Aging

- Anti-aging Mechanism of Wild Ginseng Ddobyul-

Wild ginseng Ddobyul extract suppresses the natural aging process, facilitating the restoration of young, healthy skin. Moreover, wild ginseng Ddobyul promotes the increase in fibroblast cells, which produce collagen, responsible for skin elasticity.

When applied to UV damaged skin cells express MMP-1 genes, which are responsi-ble for the breakdown of collagen, wild gingseng Ddobyul not only suppresses the expression of MMP-1 to protect collagen, but further more restores the manifesta-tion of damaged cells. This efficacy of Ddobyul is verified to be more superior than retinoic acid, which is the strongest anti-aging substance yet discovered.

Efficacy analysis confirmed the anti-oxidation effect of wild ginseng Ddobyul. This strong anti-oxidation activity of wild ginseng Ddobyul protects skin cells.

Efficacies of Ginseng Stem Cell

Dry Skin

Product Features


Ginseng Stem Cell Patent Application & Registration

▣ Application of patent on the anti-aging and anti-oxidation efficacy of plant stem cell

(Patent Application Number: 10-2009-0052340)

▣ INCI (International Nomenclature of Cosmetic Ingredients) registration

(Registration Number: 2-03-2008-7672)

Anti-Aging

Proliferation of Fibroblast Anti-aging effect by re-ducing collagen dissolu-tion caused by UV rays

Anti-oxidant effect of ginseng Ddobyul extract

Excellent compared to Retinoic acid which is famous for anti-oxi-dant effect

UV Damage Restoration

Anti-Oxidant

Dry Skin

Product Features


Ginseng’s key ingredient, saponin has effects of maintaining moisture/balance and is a big help in improving elasticity. The phenolic materials and non-saponin components of ginseng protect the aging and retromorphosis that developed by oxygen free radical.


Dry Skin

Product Features

Target Market

Seaweed Powder – Increases moisture retention and helps clean the skin

Ginseng Extract – Improves skin’s health, increases elasticity

Olive Oil – Skin moisturizing and regeneration

Seaweed powder is made from blue belt which is abundant in amino acids and minerals and gives nutrients to damaged skin. It also increases the skins moisture retention and makes the skin bright and moist.

The primary origin of the olive tree is in the Mediterranean and has a lot of phenols and polyphenols. It contains many antioxidant materials like hydrocarbon, vitamin A, D, E and has a very excellent anti-aging and moisturizing effect and is very prominent in skin care.


Features of Ginseng Cleansing Bar

Stage 1

Stage 2

Stage 3

Stage 4

Others

Improving moist through various moisturizing elements

Generating fibroblast to strengthen dermal tissue

Revitalizing damaged cells through cell activity improvement

Enhancing immunity through anti-oxidant activity

No artificial fragrance, color,

synthetic preservatives added

Refreshing application

Ginseng Stem Cell Broth Cacao powder

Ginseng Stem Cell Broth

Red Ginseng Extract

Seaweed powder, Olive oil

Dry Skin

Product Features


Dry Skin

Product Features

소구 대상

세안후 피부관리 step1!

세안 후 내 피부가 가장 처음 만나는 SUPER TONER! 피부에 남아있을 노폐물을

최종적으로 제거해주며 유연한 피부로 정돈합니

다 .

촉촉하고 영양감있는 토너

프레쉬한 시트러스향의 에센스 타입 토너로 건조한 피부에

최대한 영양과 수분을 보충하며 최대한 빨리 촉촉함을

부여해주는 실키한 마무리감의 스페셜 케어 토너 .

Target Market



Features · Concept

<Moisturizing and Anti-aging · Dryness · Fine Line Prevention>Wild Ginseng stem cell culture media and red ginseng extract that helps moisturizing, soothing, and fine line prevention. Contains seaweed powder for skin hydration and elasticity.

Target Market

• Customers that want to prevent fine line wrinkles• Customers with reddish and sensitive skin• Customers who require skin regeneration• Customers who need skin hydration

Key IngredientsWild Ginseng stem cell culture media (2%) , purified water, glycerin, tri-

closan, red ginseng extract, seaweed powder, olive oil, cocoa powder and fragrances

Volume 100g

How to use





Tomato PSC Cleansing Bar

Loose Skin

Product Features

Target Market

• Damaged collagen fiber

• Loose elasticity of Elastin fiber

• Decrease in Hyaluronic Acid loosing

moisture retention

• Fine wrinkles

• Tissue damage from UV rays

Characteristics of loose skin

Internal. External factors of loose skin

< Collagen fibers and elastic fibers >

Cau

ses

UV Rays

Smoking

Nutritive conditions

Stress

Eating Habits

Climate change

Sickness

Sym

pto

ms

Solution

Strengthen Fibroblast

proliferationSuppress active

oxygenSufficient nutrition

supplyImmune

enhancement

Tomato PSC Cleansing BarTomato PSC Cleansing Bar

Concepts of Tomato Cleansing Bar

A Tomato PSC Cleansing Bar making tight and vital skin by

concentrated treatment of loose skin and cell energy short-

age

Improve ElasticityImprove Wrinkles

& Cell ActivityWhitening & Dark Circle

Kukiga Extract

Tomato Stem Cell Broth

Tomato Juice

Houttuynia Cor-data Extract

Arbutin

Facilitate Protein Synthesis

Suppress active oxygen

Strengthen Fibrob-last Proliferation

Skin Relief

Recover Skin Protec-

tion

Nutrition Supply

Skin Regenera-

tion

Anti-Oxidant

Loose Skin

Product Features

Target MarketTomato PSC Cleansing BarTomato PSC Cleansing Bar

Efficaciec of Tomato

It is said in Europe, ‘when tomato ripes red, doctors turn

pale.’ This explains that the efficacies of the tomatoes are

excellent.

In a ripe tomato, there are plenty of lycopene. Lycopene

has twice the anti-cancer effect than the carotin, a well-

know anticancer drug. It discharges carcinogen substances

from the body before it is fully formedIt is specially effective on preventing prostate and lung cancer, and the lycopene contained

increases seven-fold once the tomato is ripe

Other than that, vitamin C and rutin brings down the blood pressure and strengthens the

capillary vessel. Vitamin K helps to prevent osteoporosis and dementia.

Tomato also contains fructose, glucose, vitamin C, B1, and B2 which has excellent anti-

aging effects. It is known to be edible sunscreen.

Especially, the vitamins and the minerals in the tomato speeds up the metabolism which

makes the skin clear and refreshing. Vitamins B smoothes the skin and hair, and Vitamin E

helps to prevent aging and to keep vital skin.

Loose Skin

Product Features


Efficacies of Tomato Stem Cell

Suppression of active oxygen increased by UV Stress

※ NAC is a powerful anti-oxidant substance discovered by Kai and his research team in 1999

Tomato Stem Cell

UV- UV+(30mJ/cm2)

- Tomato stem cell (10~50 ug/ml) appears to be efficient in suppressing active oxy-

gen compared with NAC (N-Acetyl-L-Cysteine)..

Loose Skin

Product Features


Facilitation of procollagen biosynthesis when tomato stem cell is applied

- expected to be effect on wrinkles due to positive results of procollagen

facilitation comapred with positive control

* Causes of wrinkles : collagen reduction and MMP-1(collagen breakdown enzyme) revelation in-crease

Density : Tomato stem cell 50ppm, tomato broth 10%, TGF-beta 10ng/ml

Control TGF-beta Tomato Stem Cell Tomato broth

Loose Skin

Product Features


Efficacies of Tomato Stem Cell


Loose Skin

Product Features

Target Market

Arbutin that is extracted from blueberry trees is a natural whitening ingredient that has the added sugars of hydroquinone and is widely known as a stable element. Also, Tyrosinase suppresses the production of melanin in the skin which is the cause of spots and freckles. It gives a whitening effect on the skin and causes relatively low stimulation and is harmless to the body.

Arbutin – Skin whitening, pigment removal

An amazing mystery medical plant called houttuynia have been used medicine since very long time, and the decanoyl acetaldehyde which has very unique smell from the leaf, has extremely strong to sterilizing power. Also, a special ingredient in houttuynia called cuerchitrun has power to extend capillary vessel to clean the blood, and remove the poison in a skin for brightning skin and controlling troubles on a skin.

Houttuynia Extract – Clear skin, Dark circles

Lycium - Increase elasticity, anti-aging

Lycium extracts have antibacterial and antioxidant effects and improves the skins elasticity and absorbs UV light to prevent aging. In addition to whitening by convergence activity, it maintains the skin’s texture and helps shrink pores.

Tomato PSC Cleansing BarTomato PSC Cleansing Bar

Features of Tomato Cleansing Bar

Stage 1

Stage 2

Stage 3

Stage 4

Others

Improving wrinkles through anti-aging effects

Strengthening dermal tissue important in anti-aging

Improving skin elasticity

Improving skin tone

No artificial fragrance, color,

synthetic preservatives added

Refreshing application

Tomato Stem Cell Broth Tomato Juice

Arbutin, Houttuynia Cordata Extract

Kukiga Extract

Tomato Stem Cell Broth Houttuynia Cordata Extract

Loose Skin

Product Features




Features · Concept

<Moisturizing and Anti-aging · Brightening · Wrinkle Reduction>Tomato stem cell culture media for anti-aging, Houttuynia that helps whitening, lycium extract, arbutin that helps brightening and wrinkle reduc-tion.

Target Market• All customers who worry about their wrinkles• Customers that want to regain skin elasticity and look younger• Customers with dark pigmentation of skin

Key IngredientsTomato stem cell culture media (2%) , purified water, glycerin, triclosan, houttuynia cordata extract, lycium extract, arbutin, tomato juice and fra-

grance

Volume 100g

How to use



Loose Skin

Product Features

소구 대상Target MarketTomato PSC Cleansing BarTomato PSC Cleansing Bar

Technology

Cleansing Soap