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cBio Cancer Genomics PortalTutorial: The Network View
- Genes in context of biological interactions- Genomic profiles overlaid on interaction network- Filtering by genes of interest, interaction type & source, and genomic profile- Automatic network layout- Exporting as an image
Genes in context of biological interactions
Others link seeds throughinteractions complied inPathway Commons
Interactions
Seed (specified) genes
Genomic profiles overlaid on interaction network
Genomic profile data (mutation, copy number and mRNA expression profiles)
White to red color gradient for frequency of total alteration
Filtering by genes of interest
Hide selected genes from the network
Search genes by name
Select genes from canvas or gene list under Genes tab
Filtering by interaction type & source
Interactionsmerged by default
Shown individually
Type (color-coded) & source shown in interaction details
Filtering by interaction type & source
Partial RB pathway with GBM genomic profile data.
Filtering by interaction type & source
Uncheck
Click
Same pathway after filtering applied for edge types and sources
Slide to threshold value
Filtering by genomic profile
Same pathway after genes with total alteration frequency 12% or less filtered out
TP53pathway
Or type threshold value
Automatic network layout
Recalculate layout
Recalculate layout upon filtering operations
Open Layout Options Dialog
Hover over option to get quick help
Exporting as an image
Save current network view as PNG image
