Embed Size (px)
Citation preview
"an emerging discipline that uses engineering principles to design and assemble biological components"
Wellhausen, Rachel, and Kenneth A. Oye. "Intellectual Property and the Commons in Synthetic Biology: Strategies to Facilitate an Emerging Technology." Science, Technology and Innovation Policy, 2007 Atlanta Conference on. IEEE, 2007.
"an emerging discipline that uses engineering principles to design and assemble biological components"
Wellhausen, Rachel, and Kenneth A. Oye. "Intellectual Property and the Commons in Synthetic Biology: Strategies to Facilitate an Emerging Technology." Science, Technology and Innovation Policy, 2007 Atlanta Conference on. IEEE, 2007.
"designing and constructing biological modules, biological systems, and biological machines for useful purposes."
Nakano, Tadashi (2013). Molecular Communication. Cambridge.
"an emerging discipline that uses engineering principles to design and assemble biological components"
Wellhausen, Rachel, and Kenneth A. Oye. "Intellectual Property and the Commons in Synthetic Biology: Strategies to Facilitate an Emerging Technology." Science, Technology and Innovation Policy, 2007 Atlanta Conference on. IEEE, 2007.
"designing and constructing biological modules, biological systems, and biological machines for useful purposes."
Nakano, Tadashi (2013). Molecular Communication. Cambridge.
“design and construction of novel artificial biological pathways, organisms or devices, or the redesign of existing natural biological systems."
http://www.synbioproject.org/topics/synbio101/definition/
Synthetic biology
Genetic engineering
Common circuit diagram symbols (US symbols)
Synthetic Biology Open Language (SBOL) standard visual symbols for use with BioBricks Standard
Gardner, Timothy S., Charles R. Cantor, and James J. Collins. "Construction of a genetic toggle switch in Escherichia coli." Nature 403.6767 (2000): 339-342.
Number of Regions: 5Number of teams: 280Number of participants: 5018
The Edinburgh University 2009 iGEM Team
The Edinburgh University 2009 iGEM Team
The Edinburgh University 2009 iGEM Team
https://playingwithbacteria.wordpress.com/2012/05/02/five-tips-for-coming-up-with-a-winning-igem-project/
Five tips for coming up with a winning iGEM project
1. Start from a problem
2. Start from an advance or discovery
3. Find something cool, then add ‘Bio’ in front of it, or ‘coli’ to the end of it
4. Start as broad as you can
5. Browse the registry & past teams’ work
Craig Venter
https://www.youtube.com/watch?v=HLP6x4h1tOM
JCVI-syn3.0 (Image: Tom Deerinck and Mark Ellisman of the National Center for Imaging and Microscopy Research at the University of California at San Diego)
Mycoplasma mycoides
473 genes
149 genes with unknown function
https://www.youtube.com/watch?v=SEh7Jh775iM
https://www.youtube.com/watch?v=LSXZLs9OS8k
Kopi luwak
Kopi luwak
Unique sugar profile of Cultured Coffee vs control (liquid and gas chromatography, HPAEC)
Kopi luwak
Simpson’s Paradox
1973 grad school admission UC Berkley
1973 grad school admission UC Berkley
Chuang, John S., Olivier Rivoire, and Stanislas Leibler. "Simpson's paradox in a synthetic microbial system." Science 323.5911 (2009): 272-275.
Chuang, John S., Olivier Rivoire, and Stanislas Leibler. "Cooperation and Hamilton's rule in a simple synthetic microbial system." Molecular systems biology 6.1 (2010).
Dimitriu, T., Lotton, C., Bénard-Capelle, J., Misevic, D., Brown, S.P., Lindner, A.B. and Taddei, F., 2014. Genetic information transfer promotes cooperation in bacteria. Proceedings of the National Academy of Sciences, 111(30), pp.11103-11108.
