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FOUM BIOTECH-EXPOQUIMIA 2011 NANOGAP’s APPROACH TO NANOMATERIALS RESPONSIBLE MANAGEMENT: FROM SYNTHESIS TO APPLICATION

Expoquimia 2011: Forum Biotech - Daniel Fernandez

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Nanogap's approach to nanomaterials responsible management: from synthesis to application

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Page 1: Expoquimia 2011: Forum Biotech - Daniel Fernandez

FOUM BIOTECH-EXPOQUIMIA 2011

NANOGAP’s APPROACH TO NANOMATERIALS

RESPONSIBLE MANAGEMENT: FROM SYNTHESIS

TO APPLICATION

Page 2: Expoquimia 2011: Forum Biotech - Daniel Fernandez

FOUM BIOTECH-EXPOQUIMIA 2011. NANOGAP SUBNM POWDER, S.A. APPROACH TO NANOMATERIALS RESPONSIBLE MANAGEMENT FROM SYNTHESIS TO APPLICATIO N

• 1. Introduction– Created as a spin-out from the NanoMag Research Group,

University of Santiago de Compostela, Spain in 2006.

– We develop, manufacture and sell novel nanomaterials– We develop, manufacture and sell novel nanomaterials

– Industries and applications include coatings & inks, plastics &

composites, textiles, electronics and biomedical

– Properties include therapeutic, antimicrobial, conductive,

magnetic, fluorescent and catalytic

Page 3: Expoquimia 2011: Forum Biotech - Daniel Fernandez

FOUM BIOTECH-EXPOQUIMIA 2011. NANOGAP SUBNM POWDER, S.A. APPROACH TO NANOMATERIALS RESPONSIBLE MANAGEMENT FROM SYNTHESIS TO APPLICATIO N

• Moved to new fully equipped

facility in 2008 with investment in

a versatile production plant with

capacity around 1 mt/year

• US subsidiary created in 2010• US subsidiary created in 2010

• Now 11 people, with Technical,

Operations and Commercial staff

all having strong nanotechnology

backgrounds

• Strong Advisory Board including

Scientific, Legal and IPR advisors

Page 4: Expoquimia 2011: Forum Biotech - Daniel Fernandez

FOUM BIOTECH-EXPOQUIMIA 2011. NANOGAP SUBNM POWDER, S.A. APPROACH TO NANOMATERIALS RESPONSIBLE MANAGEMENT FROM SYNTHESIS TO APPLICATIO N

Wet

Chemistry

Reaction Mechanism

Particle Size

Atomic Quantum Clusters

Nanoparticles

Silver

Gold

<1nm

AQC

2. Technology & Products

Chemistry

Particle Size

Chemical / Physical Properties

Control

Morphology

Surface Functionalisation

Carrier Fluid

Dispersion Concentration

Silver

Iron Oxide

Nanoparticles

Nanofibres

Silver

5 – 50 nm

20µm x 100nm

NP

NF

Page 5: Expoquimia 2011: Forum Biotech - Daniel Fernandez

FOUM BIOTECH-EXPOQUIMIA 2011. NANOGAP SUBNM POWDER, S.A. APPROACH TO NANOMATERIALS RESPONSIBLE MANAGEMENT FROM SYNTHESIS TO APPLICATIO N

2. Technology & Products• NANOGAP processes allow for the control of a

wide range of characteristics and properties:

– Particle size

– Particle morphology

– Surface functionalisation

– Choice of carrier fluid– Choice of carrier fluid

– Dispersion Concentration

• This allows us to work closely with customers

and develop and customise products for

specific applications

• NANOGAP products are optimallydispersed allowing for ease of use through simple stir-in blending and mixing

Page 6: Expoquimia 2011: Forum Biotech - Daniel Fernandez

FOUM BIOTECH-EXPOQUIMIA 2011. NANOGAP SUBNM POWDER, S.A. APPROACH TO NANOMATERIALS RESPONSIBLE MANAGEMENT FROM SYNTHESIS TO APPLICATIO N

• 3. Regulatory ocean– More than 30 projects are being developed at ISO TC 229 -

Nanotechnologies Standards and projects under the direct responsibility of TC 229 Secretariat

– Basic science still has to be developed for supporting critical issues – Basic science still has to be developed for supporting critical issues such as:

• Safe handling of nanomaterials

• Toxicity to humans and environment

• Safe disposal

• Accurate measurements

• …

– What to do?

Page 7: Expoquimia 2011: Forum Biotech - Daniel Fernandez

FOUM BIOTECH-EXPOQUIMIA 2011. NANOGAP SUBNM POWDER, S.A. APPROACH TO NANOMATERIALS RESPONSIBLE MANAGEMENT FROM SYNTHESIS TO APPLICATIO N

• 4. NANOGAP’s Policy for Safety and Environmental

issues

Responsibility

To watch over our

products

Proactivity

To generate new

knowledge

Transparency

To share

knowledge and

practices

Objective: to

achieve solid

rock basis for

Nanoindustry

development

Page 8: Expoquimia 2011: Forum Biotech - Daniel Fernandez

FOUM BIOTECH-EXPOQUIMIA 2011. NANOGAP SUBNM POWDER, S.A. APPROACH TO NANOMATERIALS RESPONSIBLE MANAGEMENT FROM SYNTHESIS TO APPLICATIO N

• 4. Responsibility to watch over our

products/processes

– No regulations: common sense rules!

– Wet chemistry processes good for occupational hygiene– Wet chemistry processes good for occupational hygiene(no dry powder)

– Strict quality control: for better characterization of ourproduct’s behaviour

– Permanent surveillance on regulatory landscape

Page 9: Expoquimia 2011: Forum Biotech - Daniel Fernandez

FOUM BIOTECH-EXPOQUIMIA 2011. NANOGAP SUBNM POWDER, S.A. APPROACH TO NANOMATERIALS RESPONSIBLE MANAGEMENT FROM SYNTHESIS TO APPLICATIO N

• 4. Proactivity to generate knowledge

– NANOGAP has established collaboration agreementswith research groups in order to study our product´stoxicity:

• Institute of Occupational Health of Denmark

• Advancell

• USC Genomic Medicine group: studies on the citological toxicity aspects

• UDC Toxicology group: studies on the genotoxicity and work environmentaspects

– Collaboration with DSM (Novionano): they review our MSDS and give us updates on voluntary information we should include

– Participation in FP7 Nanotechnology proposals

Page 10: Expoquimia 2011: Forum Biotech - Daniel Fernandez

FOUM BIOTECH-EXPOQUIMIA 2011. NANOGAP SUBNM POWDER, S.A. APPROACH TO NANOMATERIALS RESPONSIBLE MANAGEMENT FROM SYNTHESIS TO APPLICATIO N

• 4. Transparency to share knowledge and

practices

– We actively participate on technological, industrial and regulatory platforms:

• AENOR working group on Nanotechnology (AEN/CTN GET15 –• AENOR working group on Nanotechnology (AEN/CTN GET15 –NANOTECNOLOGÍAS)

• Phantoms Foundation

• Conferences, workshops…

– In few time, NANOGAP will make available to any interested stakeholder a summary of the internal work and external knowledge on toxicity and regulation on each of our products.

Page 11: Expoquimia 2011: Forum Biotech - Daniel Fernandez

FOUM BIOTECH-EXPOQUIMIA 2011. NANOGAP SUBNM POWDER, S.A. APPROACH TO NANOMATERIALS RESPONSIBLE MANAGEMENT FROM SYNTHESIS TO APPLICATIO N

Thanks for your attention!

www.nanogap.es