Laser GenesisLaser Genesis

At The re*be Skin ClinicAt The re*be Skin Clinic

Dr. Ronald Kolegraff M.D.Dr. Ronald Kolegraff M.D.

Laser GenesisLaser Genesis

• Creates a horizontal Creates a horizontal layer of new collagen layer of new collagen just beneath the just beneath the epidermisepidermis

• Makes the skin Makes the skin thickerthicker

• Reduces rednessReduces redness• Reduces brown spots Reduces brown spots • Smoothes pores and Smoothes pores and

fine wrinkles fine wrinkles

Laser Genesis Laser Genesis Skin RejuvenationSkin Rejuvenation

Unique Microsecond 1064 nm Unique Microsecond 1064 nm Laser Procedure on the Laser Procedure on the

CoolGlide or Xeo PlatformsCoolGlide or Xeo Platforms

Laser Genesis Procedure Laser Genesis Procedure • Excellent for treatment of:Excellent for treatment of:

– Pore size and texturePore size and texture– Diffuse erythemaDiffuse erythema– RosaceaRosacea– PoikilodermaPoikiloderma– ScarsScars

• Unique microsecond 1064 nm Unique microsecond 1064 nm laser procedure introduced by laser procedure introduced by Cutera in 2002Cutera in 2002

• Safe for any skin type and Safe for any skin type and tanned skintanned skin

• Comfortable with an excellent Comfortable with an excellent safety profilesafety profile

Pore Size Reduction

Texture

Rosacea

Hemoglobin absorption used to heat (not damage) fine upper vascular plexus

Water absorption used to heat upper dermis

Results in stimulation of new collagen production

Targets for Laser Genesis Targets for Laser Genesis ProcedureProcedure

• Thermal camera demonstrates heating of the treatment Thermal camera demonstrates heating of the treatment areaarea – Uniform background heating of treatment area withUniform background heating of treatment area with

localized heating with each individual pulselocalized heating with each individual pulse

• By evenly distributing the pulses, the heat build up will be By evenly distributing the pulses, the heat build up will be

uniform and comfortable.uniform and comfortable.

Treatment Technique – Thermal Treatment Technique – Thermal ImageImage

Typical Laser Genesis Typical Laser Genesis Treatment ParametersTreatment Parameters

•Fluence, Pulse Duration, Spot Size, Repetition RateFluence, Pulse Duration, Spot Size, Repetition Rate– Fluence: 13-14 J/cmFluence: 13-14 J/cm22 – Short pulse durations for small targets: 0.3 msShort pulse durations for small targets: 0.3 ms– Small spot size for limited penetration: 5 mmSmall spot size for limited penetration: 5 mm– Rep rate selected for gradual heating of the area: 5 to 10 HzRep rate selected for gradual heating of the area: 5 to 10 Hz

•Pulses applied with laser handpiece in constant motion Pulses applied with laser handpiece in constant motion approximately 1 to 2 cm above the skinapproximately 1 to 2 cm above the skin

•No cooling or gel requiredNo cooling or gel required

•Number of pulses for total face: 5,000 to 10,000Number of pulses for total face: 5,000 to 10,000

•15 to 30 minute treatments15 to 30 minute treatments

•Average number of treatments: 5Average number of treatments: 5

Clinical StudyClinical Study•Peer-reviewed articlePeer-reviewed article

– Non-Ablative Facial Remodeling; Erythema Reduction and Non-Ablative Facial Remodeling; Erythema Reduction and Histologic Evidence of New Collagen Formation using a 300-Histologic Evidence of New Collagen Formation using a 300-microsecond 1064-nm Nd:YAG Lasermicrosecond 1064-nm Nd:YAG Laser

– Chrys D. Schmults, MD; Robert Phelps, MD: David J Chrys D. Schmults, MD; Robert Phelps, MD: David J Goldberg, MDGoldberg, MD

– Arch Dermatology, Vol 140 (Nov 2004) p. 1373 – 1376Arch Dermatology, Vol 140 (Nov 2004) p. 1373 – 1376

Electron micrographs showing neo-collagenesis from pre-treatment to 3 months post-treatment

Pre Treatment 1 month after Tx 3 months after Tx

Patient Satisfaction Patient Satisfaction

• Laser Genesis patients sometimes fall asleep Laser Genesis patients sometimes fall asleep during the procedureduring the procedure

• They love the way their skin feelsThey love the way their skin feels• They almost always come back for follow-up They almost always come back for follow-up

treatmentstreatments

• Laser Genesis is the #1 revenue source for Laser Genesis is the #1 revenue source for many Cutera customers and part of almost many Cutera customers and part of almost every rejuvenation packageevery rejuvenation package

Pre Treatment 3 Months after 3rd Treatment

Rosacea on the CheekParameters – 14 J/cm2, 0.3 ms, 5 mm (Laser Genesis) Photos courtesy of David Goldberg, MD

Treatment of RosaceaTreatment of Rosacea

Prior to First Tx Prior to Second Tx (2 weeks after first Tx)

1Month after third/final Tx

Prior to third Tx (4 weeks after first Tx)

3 Months after third & final Tx

GA06 Left1Pre GA06 Left2 GA06 Left3

GA06 Left4 GA06 Left5Final

Photos Courtesy of Dr. Don Photos Courtesy of Dr. Don GrootGroot

Before Before 3 weeks after 3 weeks after 33rdrd Treatment Treatment

Treatment of Texture and Treatment of Texture and Diffuse RednessDiffuse Redness

Before 7 weeks after 6th treatmentApproximately 7000 pulses to full face and 2000 pulses to

each cheek

Photos courtesy of Kevin Smith, MD

Treatment of Pore Size and Treatment of Pore Size and TextureTexture

Before After 5th treatment

Approximately 2400 pulses to each side of the neck

Photos courtesy of Kevin Smith, MD

Treatment of PoikilodermaTreatment of Poikiloderma

Photos courtesy of Leonardo Rasi, MD

Before After 2 treatments

Treatment of PoikilodermaTreatment of Poikiloderma

Photodamaged Upper Lip, 1 Rx, 3 wks, 6000 Photodamaged Upper Lip, 1 Rx, 3 wks, 6000 pulsespulses

Photos courtesy of Bruce Russell, MD

Treatment of Fine LinesTreatment of Fine Lines

Treatment of Acne ScarringTreatment of Acne Scarring

Photos courtesy of Steven Ross, MD

Before 4 weeks after 5 treatments

Treatment of ScarsTreatment of Scars

Photos courtesy of Eileen Slutsky, RN

Before After 6 treatments