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CHEMOTHERAPY NURSES ROLE
Mrs. Karuna Laggeri
CLASSIFICATION OF CHEMOTHERAPY DRUGS
Alkylating Agents
Aniti - Metabolites
Micro tubule inhibitors
Anti –tumor antibiotics
Topoisomerase inhibitor
Cyclophosphamide
Ifosphamide
CarboplatinCisplatin
ChlorambucilMelphalanCarmusstine
Oxaliplatin
Temzolamide
5-fluorouracil
CapecitabineGemcitabine
MethotrexateMercaptopurineCytosine arabinoside
VincristineVindesineVinblastine
TaxanesPaclitaxeldocetaxel
Anthracyclines DaunorbicinDoxorubicinEpirubicinMitoxantrone
Bleomycin
Lrinotecan topotecan
CELL CYCLE
CHEMOTHERAPY DRUGS
TARGETED THERAPY( BIOTHERAPY)
Drugs which identify and kills only cells of intrest
Eg: Monocolonal anibodiestrastuxumab in breast cancer
INDICATION FOR CHEMOTHERAPY
Neoadjuvant chemotherapy Induction chemotherapy
Induction chemotherapy consolidation chemotherapy(Anterior chemotherapy) maintenance chemotherapy Adjuvant chemotherapy Maintenance chemotherapy Palliative chemotherapy
cancer
Solid organ malignancie
s
Hematological malignancies
PREPARATION OF DRUGSEquipment types
Bio hazard safety cabinet
Class -I
Class-II&III
Laminar flow cabinet
Fumes Hood
LAMINAR AIR FLOW
LAMINAR AIR FLOW Functioning Purposes Spillage management Certification Do & Don’ts Cleaning and disinfection
GOAL FOR CHEMOTHERAPY Curative Control palliative
ROUTES OF ADMINISTRATION
Oral Subcutaneous/ IM Intravenous Intra thecal Intra vesical Intra peritoneal
ADMINISTRATION
Intra venous types
central
PICC TunneledEg: Hickman
catheter
Non-Tunneled
Eg: IJVImplantable port
peripheral
INTERNAL JUGULAR VEIN
PICC LINE
HICKMAN CATHETER
PORT
INTRA THECAL
INTRA VESICLE CHEMOTHERAPY
INTRA PERITONEAL CHEMOTHERAPY
MAINTENANCE AND CARE OF CATHETER
Accessing Central Venous Catheters Blood Draws from Central Venous
Catheters Flushing technique Changing Catheter Site Dressing
COMPLICATIONS Pneumothorax Heamatoma Heamorrage Injury to artery& surrounding structure Blood stream infection Catheter occlusion Thrombolic occlusion Embolism
SIDE EFFECTS OF CHEMOTHERAPY
Fatigue Nausea & vomiting Diarrhea Alopesia Stomatitis Loss of appetite Leukopenia Memory loss Osteoporosis
THANK YOU