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Mapping of Images from Different Laboratory Imaging Environments into Central Imaging Archives
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Mapping of Images from Different Laboratory Imaging Environments into Central Imaging
Archives
Md Mostafizur [email protected]
3rd ITIS Research Day, TU Braunschweig
08-07-2013
Multiple Sclerosis (MS)
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Background Multiple Sclerosis MRI has become a major tool for the diagnosis of MS
SS 2013 – Medical Informatics – [email protected]
Background: The Competence Network Multiple Sclerosis (KKNMS)
Organization and geographical structure of the KKNMS (2012)http://www.kkn-ms.de/
3SS 2013 – Medical Informatics – [email protected]
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B7.3 (DTI)
MS-BB MRI*
PatternMS/NMO
Cohort
Central MRI-DB
20 study centersCohort Study
2 coordination offices (Gö + Bo)
20 study centersCohort Study
2 coordination offices (Gö + Bo)
standardized MRI
GöSubproject
PatternMS/NMO
GöSubproject
PatternMS/NMO
unstandardized MRI
post mortem MRIa
Bo+M+MzSubproject B7.3
Bo+M+MzSubproject B7.3 DTI a
GöQuality assurance
and biomarker research
GöQuality assurance
and biomarker research
Bo Quality assurance
Bo Quality assurance
MAlgorithm validation
MAlgorithm validation
MzBiomarker research
MzBiomarker research
Gö, SubprojectMS-Brain Bank Gö, SubprojectMS-Brain Bank
KKNMS: Multiple Sub-Projects
GöFuture research
GöFuture research
OnetimeRegular
Regular
Multiple times
Regular
Multiple times
Data importData export
SS 2013 – Medical Informatics – [email protected]
Research Project
• My first step is to analyze two imaging software solutions (XNAT, CHILI) and Identify the limitations to handle the interface.
• Second step is to investigate the data lifecycle and workflow from the study center to the research environment (and beyond).
– Segregate the curbs and pronounce the parameters to contribute data provenance transparency.
5SS 2013 – Medical Informatics – [email protected]
Göttingen Coordinator Office
Bochum Coordinator Office
Cohort Database Göttingen
CHILI
Study Center-1 Study Center -2 Study Center-3 Study Center-4 Study Center-5 Study Center-6 Study Center-20
Upload Via CHILI Web Interface
CD Copy (Postal Service)
Upload Via CHILI Web Interface
KNMS
Subject Identification Code
Patient Name
Patient ID
MRI Study
Image
CHILI Data hierarchy
6SS 2013 – Medical Informatics – [email protected]
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XNAT developed by the Neuroinformatics Research Group at the Washington University, St. Louis.
XNAT Image Data Hierarchy
XNAT database
Project
Patient ID
Patient Name
MRI Study
Image
Subject
Session
DICOM metadata
SS 2013 – Medical Informatics – [email protected]
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Own System
Own System Own
System
Mainz Local Research Institute
Munich Local Research Institute
Bochum Local Research Institute
Göttingen Coordinator Office
Bochum Coordinator Office
Cohort Database
CHILI
XNAT
Study Center-1 Study Center -2 Study Center-3 Study Center-4 Study Center-5 Study Center-6 Study Center-20
Upload Via CHILI Web Interface
Göttingen Local Research Institute
Database
CD Copy (Postal Service)
Upload Via CHILI Web Interface
COHORT Project
Analyze Data Structure and Data
Transmission
Analyze Data Structure and Data
Transmission
SS 2013 – Medical Informatics – [email protected]
Göttingen Coordinator Office
Bochum Coordinator Office
Cohort Database Göttingen
CHILI
Study Center-1 Study Center -2 Study Center-3 Study Center-4 Study Center-5 Study Center-6 Study Center-20
Upload Via CHILI Web Interface
CD Copy (Postal Service)
Upload Via CHILI Web Interface
Investigate MRI Data Lifecycle
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Pronounce the Parameters
•Media disruptions •Current limitations
•Pitfalls
SS 2013 – Medical Informatics – [email protected]
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Evaluate the possibility of designing a system based on internationally standardized IHE profiles/components that covers the complete data lifecycle for MRI data in biomedical research projects.
Thesis
SS 2013 – Medical Informatics – [email protected]
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Prof. Otto RienhoffDirector, Institute of Medical Informatics.
Karoline BuckowKKNMS Research Project
Institute of Medical Informatics
SS 2013 – Medical Informatics – [email protected]
Thomas FrankeHead (Imaging Network Research Group)
Lika Svanadze Md Mostafizur Rahman
“Imaging Network” Research Group
Thank you
Further Questions and Advice
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