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Dr. Md.Toufiqur Rahman MBBS, FCPS, MD, FACC, FESC, FRCP, FSCAI,
FCCP,FAPSC, FAPSIC, FAHA
Associate Professor of CardiologyNational Institute of Cardiovascular Diseases
Sher-e-Bangla Nagar, Dhaka-1207Consultant, Medinova, Malbagh branch
Honorary Consultant, Apollo Hospitals, Dhaka and Life Care Centre, Dhanmondi
Fractional flow reserve
Technique used in coronary catheterization to measure pressure differences across a coronary artery stenosis (narrowing, usually due to atherosclerosis) to determine the likelihood that the stenosis impedes myocardial ischemia.
Fractional flow reserve
• http://www.cathlabdigest.com/article/return-ic-adenosine-ffr-history-dose-technique Issue number: volume 23 - issue 12 - December 2015
• Adenosine: 6mg/500cc NS (12mcg/cc)
• IC boluses:○ –60 mcg (5 cc)○ –96 mcg (8 cc)○ –120 mcg (10 cc)
• IV drip 140 mcg/Kg/Min
Microvascular hyperemia DrugsAdenosin
FFR Limitation & Disadvantage
FFR assess of lesion severity.
FFR invasive test and allows real-time estimation of the effects of a narrowed vessel.
No plaque morphology information.
physical exercise or some intravenous medication is to increase the workload and oxygen demand of the heart muscle, and ischemia is detected using ECG changes or Nuclear imaging.
