Banned Medicines Still Selling In India

Here are some of the Drugs that have been globally discarded but are available in Indian markets:

AnalginIt is a painkillerReason for ban: Bone marrow depression.Brand name: Novalgin

CisaprideFor acidity, constipationReason for ban: Irregular heartbeatBrand name: Ciza, Syspride

DroperidolAnti-depressant. Reason for ban : Irregular heartbeat.Brand name: Droperol

FurazolidoneAnti-diarrhoealReason for ban: CancerBrand name: Furoxone, Lomofen

NimesulidePainkiller, feverReason for ban: Liver failureBrand name: Nise, Nimulid

NitrofurazoneAnti-bacterial creamReason for ban: CancerBrand name: Furacin

PhenolphthaleinLaxativeReason for ban: CancerBrand name: Agarol

PhenylpropanolamineCold and coughReason for ban: strokeBrand name: D’cold, Vicks Action – 500

OxyphenbutazoneNon-steroidal anti-inflammatory drugReason for ban: Bone marrow depressionBrand name : Sioril

PiperazineAnti-wormsReason for ban: Nerve damageBrand name: Piperazine

QuiniodochlorAnti-diarrhoealReason for ban: Damage to sightBrand name: Enteroquinol

Tegaserod

Tegaserod is a drug that is used to treat patients with irritable bowel syndrome with predominantly constipation. It was withdrawn from the market since patients taking this drug showed increased incidence of heart attack and stroke.

Human Placental extract

Human placental extract is used in the cosmetic industry in the form of lotion, gel and injection. It is not permitted in some countries since it can transmit diseases to the user. It is under the scanner and may be banned in the future.

Thioridazine

Thioridazine is an antipsychotic drug. It causes adverse effects like arrhythmia (abnormal heart rhythm), eye damage, and a condition called neuroleptic malignant syndrome.

Read more: http://www.funonthenet.in/forums/index.php?topic=208345.0#ixzz2KDlMoVhE

Vicks Action 500 is the brand name of a combination medicine that contains: paracetamol 500 mg + phenylpropanolamine (PPA) 25 mg + caffeine 32 mg per tablet. Paracetamol is a pain-killer while PPA is a decongestant. Caffeine is added to counteract the sedative side effect of PPA.  Vicks Action 500 is not a very safe medicine because one of its ingredients (PPA) is banned in nearly all European and North American countries. PPA has been implicated in causation of stroke - a potentially dangerous and life-threatening side effect. Unfortunately the Indian drug control system due to a variety of non-scientific reasons has not banned the use of PPA in India. (Source: doctor.ndtv.com)

Read more: http://www.funonthenet.in/forums/index.php?topic=208345.0#ixzz2KDmCNfa0

Drugs Prohibited from the date of Notification

1. Amidopyrine.

2. Fixed dose combinations of vitamins with anti–inflammatory agents and tranquilizers.

3. Fixed dose combinations of Atropine in Analgesics and Antipyretics.

4. Fixed dose combinations of Strychnine and Caffeine in tonics.

5. Fixed dose combinations of Yohimbine and Strychnine with Testosterone and Vitamins.

6. Fixed dose combinations of Iron with Strychnine, Arsenic and Yohimbine.

7. Fixed dose combinations of Sodium Bromide/chloral hydrate with other drugs.

8. Phenacetin.

9. Fixed dose combinations of antihistaminic with anti-diarrhoeals.

10. Fixed dose combinations of Penicillin with Sulphonamides.

11. Fixed dose combinations of Vitamins with Analgesics.

12. Fixed dose combinations of any other Tetracycline with Vitamin C.

13. Fixed dose combinations of Hydroxyquinoline group of drugs with any other drug except

for preparations meant for external use.

14. Fixed dose combinations of Corticosteroids with any other drug for internal use.

15. Fixed dose combinations of Chloramphenicol with any other drug for internal use.

16. Fixed dose combinations of crude Ergot preparations except those containing Ergotamine,

Caffeine, analgesics, antihistamines for the treatment of migraine, headaches.

17. Fixed dose combinations of Vitamins with Anti TB drugs except combination of Isoniazid

with Pyridoxine Hydrochloride (Vitamin B6).

18. Penicillin skin/eye Ointment.

19. Tetracycline Liquid Oral preparations.

20. Nialamide.

21. Practolol.

22. Methapyrilene, its salts.

23. Methaqualone.

24. Oxytetracycline Liquid Oral preparations.

25. Demeclocycline Liquid Oral preparations.

26. Combination of anabolic Steroids with other drugs.

27. Fixed dose combination of Oestrogen and Progestin (other than oral contraceptive)

containing per tablet estrogen content of more than 50 mcg (equivalent to Ethinyl

Estradiol) and progestin content of more than 3 mg (equivalent to Norethisterone Acetate)

and all fixed dose combination injectable preparations containing synthetic Oestrogen and

Progesterone. (Subs. By Noti. No. 743 (E) dt 10-08-1989)

28. Fixed dose combination of Sedatives/ hypnotics/anxiolytics with analgesics-antipyretics.

29. Fixed dose combination of Rifanpicin, isoniazid and Pyrazinamide, except those which

provide daily adult dose given below:

Drugs Minimum Maximum

Rifampicin 450 mg 600 mg

Isoniazid 300 mg 400 mg

Pyrazinamide 1000mg 1500 mg

30. Fixed dose combination of Histamine H-2 receptor antagonists with antacids except for

those combinations approved by Drugs Controller, India.

31. The patent and proprietary medicines of fixed dose combinations of essential oils with

alcohol having percentage higher than 20% proof except preparations given in the Indian

Pharmacopoeia.

32. All Pharmaceutical preparations containing Chloroform exceeding 0.5% w/w or v/v

whichever is appropriate.

33. Fixed dose combination of Ethambutol with INH other than the following: INH

Ethambutol 200 mg. 600 mg. 300 mg. 800 mg.

34. Fixed dose combination containing more than one antihistamine.

35. Fixed dose combination of any anthelmintic with cathartic/purgative except for

piperazine/Santonim.

36. Fixed dose combination of Salbutamol or any other bronchodilator with centrally acting

anti-tussive and/or antihistamine.

37. Fixed dose combination of laxatives and/or anti-spasmodic drugs in enzyme preparations.

38. Fixed dose combination of Metoclopramide with systemically absorbed drugs except

fixed dose combination of metoclopramide with aspirin/paracetamol

39. Fixed dose combination of centrally acting, antitussive with antihistamine, having high

atropine like activity in expectorants.

40. Preparations claiming to combat cough associated with asthma containing centrally acting

antitussive and/ or an antihistamine.

41. Liquid oral tonic preparations containing glycerophosphates and/or other phosphates and /

or central nervous system stimulant and such preparations containing alcohol more than

20% proof.

42. Fixed dose combination containing Pectin and/or Kaolin with any drug which is

systemically absorbed from GI tract except for combinations of Pectin and/or Kaolin with

drugs not systemically absorbed.

43. Chloral Hydrate as a drug.

44. Dovers Powder I.P.

45. Dover’s Powder Tablets I.P.

46. Antidiarrhoeal formulations containing Kaolin or Pectin or Attapulgite or Activated

Charcoal.

47. Antidiarrhoeal formulations containing Phthalyl Sulphathiazole or Sulphaguanidine or

Succinyl Sulphathiazole.

48. Antidiarrhoeal formulations containing Neomycin or Streptomycin or

Dihydrostreptomycin including their respective salts or esters.

49. Liquid Oral antidiarrhoeals or any other dosage form for pediatric use containing

Diphenoxylate Lorloperamide or Atropine or Belladona including their salts or esters or

metabolites Hyoscyamine or their extracts or their alkaloids.

50. Liquid Oral antidiarrhoeals or any other dosage form for pediatric use containing

halogenated hydroxyquinolines.

51. Fixed dose combination of antidiarrhoeals with electrolytes.

52. Patent and Proprietary Oral Rehydration Salts other than those conforming to the

53. Fixed dose combination of Oxyphenbutazone or Phenylbutazone with any other drug.

54. Fixed dose combination of Analgin with any other drug.

55. Fixed dose combination of dextropropoxyphene with any other drug other than anti-

spasmodics and/or non-steriodal anti-inflammatory drugs (NSAIDS).

56. Fixed dose combination of a drug, standards of which are prescribed in the Second

Schedule to the said Act with an Ayurvedic, Siddha or Unani drug.

57. Mepacrine Hydrochloride (Quinacrine and its salts) in any dosage form for use for female

sterilization or contraception.

58. Fenfluramine and Dexfenfluramine.

59. Fixed dose combination of Diazepam and Diphenhydramine Hydrochloride.

60. Rimonabant.

61. Rosiglitazone

62. Nimesulide formulations for human use in children below 12 years of age.

63. Cisapride and its formulations for human use.

64. Phenylpropanolamine and its formulation for human use.

65. Human Placental Extract and its formulations for human use.

66. Sibutramine and its formulations for human use, and

67. R-Sibutramine and its formulations for human use.

68. Gatifloxacin formulation for systemic use in human by any route including oral and

injectable

69. Tegaserod and its formulation for human use.

Why they are banned?

Drug No. 61

Rosiglitazone is an antidiabetic drug in the thiazolidinedione class of drugs. It works as an

insulinsensitizer, by binding to the PPAR receptors in fat cells and making the cells more

responsivetoinsulin.

The main reason behind banning this drug was associated with a significantly increased risk

ofheartattack.

A meta-analysis of observational studies released in March, 2011 provides more evidence

that rosiglitazone is associated with a higher risk of heart failure, myocardial infarction (MI)

and death.

Datta Nirmal

Pune

Top

Fri, 2011-10-07 15:12#2Anonymous

Nimesulide formulations for human use in children below 12 years

Some common side effects linked with Nimesulide use are nausea, vomiting, diarrhea,

pruritis, skin rashes, headaches and dizziness. Some serious side effects when used in

newborns are renal failure and hepatic failure.

According to International Society of Drug Bulletins (ISDB), this non-steroidal anti-

inflammatory drug (NSAID) offers no therapeutic advantage or better gastrointestinal safety

compared with other NSAIDs, whereas it exposes patients to a higher risk of fatal hepatic

disorders.

Nimesulide has been drawn aside from the pharmaceitical market because of its hepatic

effects (risk of hepatatoxicity) on patients.

Mahendra singh

from Panjab University, Chandigarh

Top

Thu, 2011-10-06 23:46#3Anonymous

no. 32/

In high amount chloroform can be carcinogenic and also have severe harmful effect on CNS

Top

Thu, 2011-10-06 23:27#4

Anonymous

Drug Number 60 / Rimonabant

Rimonabant is anorectic antiobesity drug. It is -1 agonist for the cannabinoid receptor CB1.

Shortly after market introduction, press reports and independent studies suggested side effects

occurred more intensely and more commonly than shown by the manufacturer in their

clinical studies. Resulting from drug actions at CB1 receptors in the brain, reports of severe

depression and suicidal thoughts are frequent.

AND IT IS WITHDRWN FROM THE MARKET.

Top

Thu, 2011-10-06 23:19#5Anonymous

No. 66 / Sibutramine and its formulations for human

Hello,

Good evening

Sibutramine is a centrally-acting serotonin-norepinephrine reuptake inhibitor structurally

related to amphetamines.

Sibutramine can substantially increase blood pressure and pulse in some patients. In 2010 the

FDA noted the concerns that sibutramine increases the risk of heart attacks and strokes in

patients with a history of cardiovascular disease.

Sibutramine has been associated with increased cardiovascular events and strokes and has

been withdrawn from the market in countries and regions including Australia, Canada, China,

the European Union, Hong Kong, India, Mexico, Thailand, the UK and the United States.

---

Kamal Patel

Manipal

Top

Thu, 2011-10-06 23:10#6Anonymous

No. 68 / GATIFLOXACIN

Hi, I am Karan Mistry

A Canadian study published in the New England Journal of Medicine in March 2006 claims

Tequin {brand name of gatifloxacin} can have "life threatening" side effects including

serious diabetes.

Other serious side effects reported with gatifloxacin include hallucinations, liver damage and

purpura. Union Health and Family Welfare Ministry of India on 18 march 2011 banned the

manufacture, sale and distribution of Gatifloxacin as it caused certain adverse side effects

Top

Mon, 2011-10-10 00:18#7Anonymous

its at serial no. 68

68

Top

Thu, 2011-10-06 16:31#8Anonymous

no. 20 / Nialamide

Nialamide is an irreversible and non-selective monoamine oxidase inhibitor

Banned May be due to extreme side effects: euphoria, psychomotor agitation, insomnia,

anxiety, headache, vertigo, tremor, hyperreflexia, manic state, or turnig a depression into

mania in bipolar disorder. Other side effects are arterial hypotension, orthostatic hypotension,

arterial hypertension, palpitations, hyperhidrosis, dry mouth, nausea, vomiting, epigastric

pain, constipation, vision problems, retrobulbar optic neuritis, polyneuritis, weight gain, acute

cardiac insufficiency, tachycardia, peripheral neuropathy, jaundice, hepatomegaly,

hyperbilirubinemia, urinary retention, elevated transaminases, cutaneous eruptions,

impotence, and delayed ejaculation.

Dangerous side effects are drug-induced hepatitis and hepatocellular insufficiency.

Top

Thu, 2011-10-06 16:24#9Anonymous

no.3 / Fixed dose combinations of Atropine in Analgesics..

Anticholinergic agents may delay and/or decrease the gastrointestinal absorption of

acetaminophen by reducing gastric motility and delaying gastric emptying. However, the

clinical relevance is probably minimal.

Top

Thu, 2011-10-06 15:52#10Anonymous

No . 54 / Analgin

Analgin known to cause agranulocytosis , widely used in Indian mmarket....

Top

Thu, 2011-10-06 15:32#11Anonymous

no-10 / Fixed dose combinations of Penicillin with Sulphonamide

Bacterial resistance is the main reason behind banning penicillin and sulphonamide

combination.

Top

Thu, 2011-10-06 15:25#12Anonymous

DRUG No. 21 / PRACTOLOL

Practolol is selective beta blocker and structurally similar as propanolol but it is banned

because of toxic effect.

* practolol disaster is considered the worst medical blunders since thalidomide.

It may cause oculomucocutaneous syndrome which is a severe syndrome whose signs include

conjunctivitis sicca and psoriasiform rashes, otitis and sclerosing serositis.

- Rohit Pagare

GLOBALLY BANNED MEDICINES STILL USING IN INDIA WHY ?

Banned  drugs  are  flourishing  through  Indian  markets lets look  some  of the  banned  drugs  which   is  highly  used  by  most  of  Indians.  Some medicines are even prescribed by doctors. Self  medication  is  the  other threat   among  peoples as  just  a  simple  cold  or 

some  pain  comes  most  of  the  affected  ones  goes  to  medical stores  or  nearby   pharmacy  and  purchase  some drugs  not  knowing  these  simple  symptoms  are the  part  of  big  picture. Lets  stop  self  medication  and  put  a habit  of visiting  hospital  so  to  make  a better  healthy  habits .let look  some of the  mostly used  drugs  in Indian  markets and their  side  effects  which  after  reading  should  shock  most  of  us.  These  drugs  are  banned  globally  then  why  it  is  selling  in India  it’s a big  irony  as  authorities  should  do  very  stern action against as  these medicines  usually cause death of the users.

Analgin

 Mostly   commonly used   as a   Pain killer  

Reason of ban is bone marrow depression 

Famous brand name novalgin.

Cisapride

 Mostly   used for acidity, constipation.

Reason   for   ban is irregular   heart beat

Some brands like ciza, syspride is commonly   used.

Phenolphthalein

Mainly used as laxative   reason for ban is this medicine cause’s cancer

Some famous brand name   agarol

DROPERIDOL:

 Used mainly as Anti-depressant. Reason for ban: Irregular heartbeat.

Brand name: Droperol 

FURAZOLIDONE:

 Used  as  antidiarrhoeal. Reason for ban: Cancer.

Brand name: Furoxone, Lomofen

NIMESULIDE:

Used as Painkiller, fever. Reason for ban: Liver failure.  

Brand name: Nise, Nimulid

NITROFURAZONE:

Used mainly as Antibacterial cream. Reason for ban: Cancer.

Brand name:  Furacin

PHENYLPROPANOLAMINE:

Used as Cold and cough. Reason for ban: stroke.

Brand name:  D'cold, Vicks Action-500

OXYPHENBUTAZONE:

Used as Non-steroidal anti-inflammatory drug. Reason for ban: Bone marrow depression.

Brand name: Sioril

PIPERAZINE:

Used as Anti-worms. Reason for ban: Nerve damage.

Brand name:  Piperazine

QUINIODOCHLOR:

Used as Anti-diarrhoeal. Reason for ban: Damage to sight.

Brand name: Enteroquinol 

DANGEROUS DRUGS:

THESE DRUGS HAVE BEEN GLOBALLY DISCARDED BUT ARE AVAILABLE IN INDIA.

The most common ones are D cold, action 500 & Nimulid  so  if  you  have  any symptoms  do  not   take  these  medicines  and  also  to do  not  give  your  dear and near ones  as  it  may  cause  serious  issues  like  stroke  and even death  visit  your  nearest  GP.