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AAmmooll AAsshhookk KKuunnddee
68 RossBrook Model farm Road, Cork
Mobile: +353-899826285
E-Mail: [email protected],
Objective: Seeking a challenging position as Computational Biologist in an organization that will
effectively utilize my experience and offers opportunity for career growth.
RESEARCH INTEREST : Remote homology detection and protein structure prediction • Genome
sequence/structure variation and disease implications • Biological data integration • Drug Designing
Development of Software & Database Tools for Analysing biological data
Profile Summary
Extensive experience of performing biological data computations and algorithm development
In-depth knowledge of computational biology and computing environments like Windows , Unix
Remarkable knowledge of Python, and SAS statistical software
Familiarity with microbiology, molecular biology, and cancer genomics
Ability to create effective SQL queries and relational database schemas
Ability to conduct statistical analysis on large biological datasets, properly
Academic programme and Certificate program
Designing a Automated Pipeline for phylogenetic analysis of clinical isolates, Cork , Ireland
Brain Tumor Classification using wavelet and Texture based Neural Network Analysis of Brain Tumor Detection Techniques through Filtering and Segmentation in Matlab
Insilico drug Designing to inhibit entry of Ebola virus through Nieman Pick- C1 Protein, Mumbai
Microarray based gene expression profiling on the role of neuropeptide s and neuropeptide s receptor 1 in asthma, Cochin, India
Insilico drug designing targeted to COCH gene in LCCI domain of human autoimmune inner ear disease, Hyderabad, India
Docking Analysis of insulin-like growth factor 1 receptor for identification of role in cancer development , Hyderabad, India
Experience working on design computer aided diagnosis algorithm to increase accuracy of brain tumor detection and classification
Part time tutor for Cork Institute of Technology in Biological Department.
Technical Skills And Laboratory Techniques
Computer Skills
OS: Window7/Window8/XP/NT, Unix/Linux/Ubuntu/ Redhat
Programming Language: Phyton, BioPython, Perl, Java, Vb.net, R-programming, MATLAB
Biochemistry and Cell Molecular Biology skills
DNA extraction, Plasmid DNA preparation, restriction enzyme digests, PCR, agarose gel
electrophoresis, SDS-PAGE, Colonies preparation of bacteria.
Bioinformatics softwares & Tools
Working Knowledge on all major Bioinformatics Software ,Structure database & analysis tools
Molecular Visualization Software: Rasmol, Pymol, Cn3d, VMD, SwissPdbviewer, MATLAB,
REACTOME, MEGA, GESTALT workbench, Bioconductor.InCroMAP
Molecular modelling & Docking Software : Modeller, Autodock3, Accelrys Discovery Studio
4.1, Sybel. Molecular operating Enviortment (MOE), NAMD/VMD
Genetic Software : Power marker, Arlequin.
Phylogenetic Analysis: RAxML, MrBayes, PhyML, Phylip, Ape
Biostatistics software : SPSS 17, R- programming language
Image processing software: ITK –Snap 3.0, signal processing in NMR(SPIN), Imaging in MATLAB
ACADEMIC
Timeline Course Details
September 2013 –
Feb 2015
(Honors)
M.Sc in Computational Biology (1 Year, Level-9, Research Masters), CIT, Cork,
Ireland.
Thesis title: Designing pipeline for phylogenetic analysis of Clinical isolates
Key Modules: Strutural Biology, molecular biology, statistics,python
September 2009 –
August 2013
First class honours
Graduate in Bioinformatics(4 Years, Level8) ,Padmashree DY Patil University of
Biotechnology & Bioinformatics, Navi Mumbai
Thesis title: Insilico drug designing to inhibit Ebola through Nieman –pick C1 protein
Key Modules: Proteomics, Perl, Java, drug designing, system biology, Matlab,
pharmacology, genetic engineering, pharmacology
Work Research Experience & Responsibility
Nsilico Biotech Labs , Computational Biologist, Cork , Ireland
Designed and created algorithms and approaches to data analysis of genomic data.
Determined and utilized effective computational techniques to develop analysis tools. Planned and
implemented computational strategies for analysis and integration of genomic data. and revised all
existing algorithms to complete computational activities, on time.
Succesfully developed an algorithm for extracting 16sRNA from RNA sequence for internal use.
Multiple databases, screen-specific information and heuristic algorithms based on blast were
developed to reliably select the best hit for each clone automatically.
Public DB-based gene annotation from EnsEMBL, Refseq, Swissprot etc.
Helped evaluating and extending various Bioinformatics software packages and databases for
internal usage.
Obtained, compiled, and interpreted information from various biological data sources.
Liaised with other computer program scientists and executed computational research activities.
Developed data analysis pipelines and executed complex data analysis.
Statistics, neural-network pattern recognition, Monte Carlo simulations, simulated annealing, multi-dimensional optimization, and dynamic programming.
JOB RESPONSIBILITIES As Bioinformatics Research Associate, Microsatbiolab, Navi Mumbai
( Jan2013-August2013)
Worked as lab assistant responsibility for maintaining computers, Rectifying technical issue in
Computer system.
Identification for finding lead compound , Using bioinformatics tools to identify and annotate genes
Optimising Quantitative structure activity relationships assays in vitro and in Vivo.
Genome Sequencing, Homology modelling , Protein structure predication.
Performing Pharmacokinetic studies, Toxicology testing, formulation developments.
Performing Protein – ligand docking, Scaffold designing, Pharmacophore studies , QSAR analysis.
Toxicological tests, AMED test.
Honours & Scholarship
The National Level School Scholarship for Secondary level Examination 1998-1999
Gold Medallist at state level Language Examination 2001-2002
Best Scout & Guide Student of the year 2001-2002
Full Scholarship for cricket Coaching at Navi Mumbai Sport club, Mumbai , 2000
Team Leader of DY PATIL SPORTS CLUB, NAVI MUMBAI 2010
International Conference & Poster Presentation
Collaborative European Research Conference(CERC) October 2013 , CIT, Cork
11th International Conference On Intergration Of Artificial Intelligence(AI) & Operation
Research(OR), UCC, Cork
Poster Presentation on “System and Synthetic Approaches for therapeutic intervention against
Leishmania”, National center for cell science, Pune
REFERENCES
Name: Dr.Roy Sleator
Office Add : C153 Cork Institute of Technology
Telephone : (353)-21-4335405
Email: [email protected]
Job Title: Head of Biological Department & Co Founder NSilico Life Science, Cork, Ireland
Name: Dr. Helen O shea
Office Add:C247L Cork Institute of Technology
Telephone: (353)-21-4335401
Email: [email protected]
Job Title: Lecturer & Researcher Investigator, CIT, Ireland
Name: Dr Paul Walsh
Office :Melbourne Building CIT Campus, Bishoptown , Cork, Ireland
Email: [email protected] , Tel:353-21-4335572
Job Title: Managing Director, NSilico Life Science Ltd
