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UFP UFP UFP UFP UFP UFP Combustion- derived or engineered, the health hazards posed are real INDUSTRIAL HYGIENISTS SHOULD ADDRESS THE RESPIRATORY HAZARDS OF NANOPARTICLES – aka UFP – IN THE WORKPLACE

Industrial hygienists should address nanoparticle respiratory hazards

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Page 1: Industrial hygienists should address nanoparticle respiratory hazards

UFP UFP UFP UFPUFP UFP

Combustion-derived or engineered, the health hazards posed are real

INDUSTRIAL HYGIENISTS SHOULD ADDRESS THE

RESPIRATORY HAZARDS OF NANOPARTICLES

– aka UFP – IN THE WORKPLACE

Page 2: Industrial hygienists should address nanoparticle respiratory hazards

Nanoparticles may seem new but UFP (<100 nm ultrafine particles) studies go back decades in outdoor air pollution research.

Engineered nanomaterials are used in consumer products, such as cosmetics, sunscreen and related personal care products such as toothbrushes.2

Industrial use of nanomaterials occurs in the manufacture of

electronics, automotive and aerospace products.2

Additive manufacturing uses 3D printers and lasers to heat/melt

/sinter powders of metal, polymer, biological nanoparticles.

Well understood source of combustion-derived nanoscale UFP is welding, for which fume extractors are effective.

WHERE EXPOSURE TO UFP OCCURS

Page 3: Industrial hygienists should address nanoparticle respiratory hazards

HOW NANOSCALE UFP CAN DAMAGE THE BODY

Heart: Acute myocardial

infarction, atherosclerosis5

Lungs: Particle-induced

inflammation3

DNA: Changes in

generic code regulation6

Brain: Cognitive decline4

Page 4: Industrial hygienists should address nanoparticle respiratory hazards

HEPA filters capture particles via diffusion, interception, inertia, van der Waals forces, plus the interplay of:

PROTECTION FROM PARTICLES STARTS WITH H, AS IN H E P A

Page 5: Industrial hygienists should address nanoparticle respiratory hazards

Particles of 0.3 microns are noted when HEPA filtration efficiency is discussed, creating the false impression that HEPA does not capture smaller particles. Research has shown HEPA filtration is 99.97% efficient at capturing 0.3 micron particles, the most difficult size for HEPA technology.1

Particles of lesser and

greater size are captured even more efficiently.

NIOSH: HEPA EFFECTIVE TOOL FOR NANOPARTICLE CAPTURE

“HEPA filtration has been shown to be effective in capturing nanoscale particles and should be considered in situations where emissions may be regular, where processes are repeated, and where higher quantities are used in a way that may lead to emissions.”

Page 58 NIOSH Current Intelligence Bulletin 65

Page 6: Industrial hygienists should address nanoparticle respiratory hazards

Nanoscale particles are a health hazard.

Solutions exist in existing air fi ltration technology.

We encourage you to seek out the information you need to solve this problem.

INDUSTRIAL HYGIENISTS SOLVE PROBLEMS

www.sentryair.com

S i m p l e s o l u t i o n s f o r c l e a n e r a i r . T M

Page 7: Industrial hygienists should address nanoparticle respiratory hazards

RESOURCES

1Workshop for Certification of Biological Safety Cabinets, The National Institutes of Health (NIH), Office of Biohazards and Environmental Control, Rockville Bio-Engineering Services, Dow Chemical USA, Bethesda, 1974 2Nanotechnology in the real world: Redeveloping the nanomaterial consumer products inventory, Beilstein Journal of Nanotechnology 2015 http://www.beilstein-journals.org/bjnano/content/pdf/2190-4286-6-181.pdf 3Combustion-derived nanoparticles: A review of their toxicology following inhalation exposure, Particle and Fibre Toxicology 2005 http://www.particleandfibretoxicology.com/content/2/1/10#B3 4Exposure to Particulate Air Pollution and Cognitive Decline in Older Women, JAMA Internal Medicine 2012 http://archinte.jamanetwork.com/article.aspx?articleid=1108716 5Silicon dioxide nanoparticles increase macrophage atherogenicity: Stimulation of cellular cytotoxicity, oxidative stress, and triglycerides accumulation, Environmental Toxicology 2014 http://onlinelibrary.wiley.com/doi/10.1002/tox.22084/abstract 6Short-term diesel exhaust inhalation in a controlled human crossover study is associated with changes in DNA methylation of circulating mononuclear cells in asthmatics, Particle and Fibre Toxicology 2014 http://www.particleandfibretoxicology.com/content/11/1/71/abstract