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Bio-based sustainable chemical intermediates for polymer bio-surfactants, bio-lubricants
Shivani GargEntrepreneurial LeadGraduate student, 3.5 yrs in biochemistry
Dr. Basil NikolauPrincipal InvestigatorProfessor, 30 yrs in biochemistry
Dr. Peter KeelingI-Corps MentorEntrepreneur, 30 yrs in biotechnology industry
I-Corps Team
Bio-based chemicalintermediates
CBiRC, Iowa State University
Interviews conducted in total – 62+38 = 100
Two minute video - http://www.youtube.com/watch?v=ZyGr-eoONqo&feature=youtube_gdataOne minute video - http://www.youtube.com/watch?v=xY9nXzlzEHA&feature=youtube_gdata
Value proposition
Problem
• Non-renewable, petroleum derived feedstock for surfactant, lubricant industry
Solution
• Sustainable, bio-based replacement
• Higher performance
• Improved cold temperature tolerance of detergents, lubricants
Features of value proposition
• Bi-functional molecules
• Flexibility in chain length
• Flexibility in branching
$1 trillion petrochemical market
Bio-based chemicals growing at 15% p.a.
$24 bnsurfactants
Growing market opportunity
Position in Value Chain
OmegaChem
- Bio-mass suppliers
- Contractual scale-up
- Technology providers
-Utility providers
• Production, yield, quality• Match customer’s
product specs
• Manufacturin
g facility• IP
• Human resources,
capital
Problem - Non-
renewable feedstock for
making polymer Solution
(Product) – Bio-based and
sustainable replacement
Features - Bi-functional and customizable
• Co-create value
proposition• Customer goodwill and
trust• Customer communities
• Physical product • Indirect
channel • Wholesale
• Existing market Polymer
manufacturers, Biotech
companies,
• New market -Novel bio-
plastic companies?
• Multi-sided market?
• Sell bio-based monomers• Added value pricing based on
customization of products• Licensing?
• Fixed – Capital• Variable – Manufacturing, Bio-
mass
Business Model Canvas 1.0
Value prop. hypothesis: Bio-based and sustainableCustomer segment hypothesis: Polymer manufacturers, new marketsTest: Talked to biochemical companies
Talked to potential customers
Value Proposition, Customer Segments: Experiments
Biochemical companies, Market research (15)
Market Research Analyst
R&D Director
Research Scientist
Senior ScientistVice-President, Technology Development Senior Scientist
Senior Business Development Manager
Surfactants: new market ($24bn)Monomer
manufacturer
Surfactant Formulator
Polymerformulator
Polymer user
Surfactant user
Consumer facingcompany
Consumer
Value Proposition, Customer Segments: Results
Monomer manufacturer
Polymerformulator
Polymer user
Consumer facingcompany
Consumer
“Have you considered surfactants
space?” - DSM
Problem - Non-renewable feedstock
Solution – Bio-based,
sustainable replacement
Features - Bi-functional,
customizable• ‘Drop-in’
monomers• Diacids (chain length: C10-C16)
• New functionalities (cyanide, amine)
• Existing market Polymer
manufacturers, Biotech
companies,Surfactants,
Home & Personal Care
sector
• New market -Novel bio-
plastic companies?
• Multi-sided market?
Business Model Canvas 4.0Value Proposition, Customer Segments: Iteration
Channel hypothesis: Indirect channel of wholesaleTest: Talked to chemical distributors
Here’s what we did…
Channels: Experiments
Distributors (9)
Biochemical industry executives (3)
Pivot: Entry barriers are key
Distributor
Distributor
Monomer manufacturer
Surfactant formulator
Polymerformulator
Polymer user
Surfactant user
Consumer facingcompany
Consumer
Channels: Results
High entry barriers(Petro-based is hard to dislodge.)
Low entry barriers(Market pull for green products)
“Petro industry wishes that you
guys did not exist!”
- Draths
Business Model Canvas 5.0Problem - Non-
renewable feedstock
Solution – Bio-based, sustainable
replacement•Regional supply of surfactant raw-
material• Avoidance of
single material sourcing (petro)• Green
Features - Bi-functional,
customizable• ‘Drop-in’
monomers
Existing markets• Polymer
manufacturers
• Biotech companies
Customer in value chainFormulator companies
Existing market sectors
• Surfactants
• Home & Personal Care sector
• Physical product
•Indirect channel • Wholesale
Distributors
Channels: Iteration
Customer Relationship Hypothesis: Co-create value propositionTests: Talked to surfactant/lubricant companies
Here’s what we did…
Catalyst Research Engineer
Tribology Section Leader
Research Scientist
Senior Scientist
Principal Scientist
Director, R&D
Program Manager
Biobased Chemicals Analyst
Vice-President, R&D
Business Marketing Leader
President, Personal Care
Global Head, R&D
Lubricants (4)Surfactants (4)
Other bio-based companies (6)
Customer Relationships: Experiments
Senior Scientist, R&D
Technical Director
Here’s what we found…
Distributor
Monomer manufacturer
Surfactant formulator
Surfactant user
Consumer facingcompany
ConsumerMarket Pull(Sustainability
agenda)
Surfactant users influence surfactant formulator decisions, so need to partner with surfactant users first!
Green Panel – Focus on reducing petroleum based products
Customer Relationships: Results
Decision Makers
Business Model Canvas 6.0Problem - Non-
renewable feedstock
Solution – Bio-based, sustainable
replacement•Regional supply of surfactant raw-
material• Avoidance of
single material sourcing (petro)• Green• High-
performance
Features - Bi-functional,
customizable• ‘Drop-in’
monomers
Customer in value chainFormulator companies
Existing market sectors
• Surfactants
• Lubricants
• Home & Personal Care sector
•Co-create value proposition
• Customer goodwill and trust• Customer communities
• Trade-shows, PR• Conferences,
surveys
Customer Relationships: Iteration
Revenue Model Hypothesis: Value-based pricing, licensing Tests: 1. Developed a product sheet
2. Talked to 7 surfactant companies3. Talked to 6 production economics
experts
Payment Flow Hypothesis
Distributor
Monomer manufacturer
Surfactant formulator
Surfactant user
Consumer facingcompany
Consumer
Revenue model: Hypothesis
Biomass supplier Biomass 15
c/lb*Biomass Range 5-
20c/lb
Monomer ?Detergent alcohols
80c/lb
Formulation ?Formulated
Surfactant 90c/lb
Surfactant 100 c/lb*
Formulated Detergent 100c/lb
Detergent 200 c/lb*
10% Surfactant in Detergent
Product
Decision Makers
*ICIS Market Intelligence, 2012
Payment Flow
Distributor
Monomer manufacturer
Surfactant formulator
Surfactant user
Consumer facingcompany
Consumer
Revenue model: Result 1
Biomass supplier Biomass 15
c/lb*Biomass Range 5-
20c/lb
Monomer 80 c/lbDetergent alcohols
80c/lb
Formulation 90 c/lbFormulated
Surfactant 90c/lb
Surfactant 100 c/lb
Formulated Detergent 100c/lb
Detergent 200 c/lb
10% Surfactant in Detergent
Product
Decision Makers
*ICIS Market Intelligence, 2012
Scale up is the key
Revenue model: Result 2
Less than 100 c/lb is achievableOptimized scale up (~500,000 lb/day)
Earlyvangelists
“You give us 1kg, we
can evaluate.”
Business Model Canvas 7.0
• Production, yield, quality• Match customer’s
product specs • Constant
innovation
• Sell bio-based monomers• Added value pricing based on
customization of products• Create demand by partnering with
Surfactant Users and then sell to Formulators• Licensing
- Cheapest bio-mass suppliers
- Contractual scale-up
- Technology providers
-Utility providers
- Surfactant Users (P&G)
Revenue Model: Iteration
Partners Hypothesis: Bio-mass suppliers, scale-up, technology providers, utility providers, surfactant usersTests: Talked to potential partners
Here’s what we hypothesized…
Distributor
Partners
Surfactant formulator
Surfactant user
Consumer facingcompany
Consumer
Partners: Hypothesis
Biomass supplier
Decision Makers
Monomer manufacturer
sStart-up
Incubators
Market Research
Scale-up providers
Technology partners
Here’s what we did…Start-up
Incubators (4)
Market Research
(3)
Scale-up providers
(4)
Technology partners
(3)
Partners: Experiments
Business Model Canvas 8.0-Market Research
Agencies
- Start-up incubators
Cheapest bio-mass suppliers
- Contractual scale-up
- Technology providers
-Utility providers
- Surfactant Users (P&G)
Partners: Iterate
What’s next?State funding (i6 grant)Federal funding (SBIR)
First to Last Business Model Canvas
- Bio-mass suppliers
- Contractual scale-up
- Technology providers
-Utility providers
• Production, yield, quality• Match customer’s
product specs
• Manufacturin
g facility• IP
• Human resources,
capital
Problem - Non-
renewable feedstock for
making polymer Solution
(Product) – Bio-based and
sustainable replacement
Features - Bi-functional and customizable
• Co-create value
proposition• Customer goodwill and
trust• Customer communities
• Physical product • Indirect
channel • Wholesale
• Existing market Polymer
manufacturers, Biotech
companies,
• New market -Novel bio-
plastic companies?
• Multi-sided market?
• Sell bio-based monomers• Added value pricing based on
customization of products• Licensing?
• Fixed – Capital• Variable – Manufacturing, Bio-
mass
Business Model Canvas 1.0First Canvas
Business Model Canvas 8.0
• Production, yield, quality• Match customer’s
product specs • Constant
innovation
Problem - Non-renewable feedstock
Solution – Bio-based, sustainable
replacement•Regional supply of surfactant raw-
material• Avoidance of
single material sourcing (petro)• Green• High-
performance
Features - Bi-functional,
customizable• ‘Drop-in’
monomers
• Sell bio-based monomers• Create demand by partnering with
Surfactant Users and then sell to Formulators• Licensing
• Manufacturing
facility• IP
• Human resources,
capital• IHS (Market
Info)
-Market Research Agencies
- Start-up incubators
Cheapest bio-mass suppliers
- Contractual scale-up
- Technology providers
- Surfactant Users (P&G)
Customer in value chainFormulator companies
Existing market sectors
• Surfactants
• Lubricants
• Home & Personal Care sector
• Fixed – Capital• Variable – Manufacturing, Bio-mass
•Co-create value proposition
• Customer goodwill and trust• Customer communities
• Trade-shows, PR• Conferences,
surveys
• Physical product
•Indirect channel • Wholesale
Distributors
Final Canvas
Evolution of Canvas
- Bio-mass suppliers
- Contractual scale-up
- Technology providers
-Utility providers
• Production, yield, quality• Match customer’s
product specs
• Manufacturin
g facility• IP
• Human resources,
capital
Problem - Non-
renewable feedstock for
making polymer Solution
(Product) – Bio-based and
sustainable replacement
Features - Bi-functional and customizable
• Co-create value
proposition• Customer goodwill and
trust• Customer communities
• Physical product • Indirect
channel • Wholesale
• Existing market Polymer
manufacturers, Biotech
companies,
• New market -Novel bio-
plastic companies?
• Multi-sided market?
• Sell bio-based monomers• Added value pricing based on
customization of products• Licensing?
• Fixed – Capital• Variable – Manufacturing, Bio-
mass
Business Model Canvas 1.0
- Bio-mass suppliers
- Contractual scale-up
- Technology providers
-Utility providers
• Production, yield, quality• Match customer’s
product specs
• Manufacturin
g facility• IP
• Human resources,
capital• SRI (Market
Info)
Problem - Non-
renewable feedstock for
making polymer Solution
(Product) – Bio-based and
sustainable replacement
Features - Bi-functional and customizable• ‘Drop-in’
monomers• Diacids
• Co-create value
proposition• Customer goodwill and
trust• Customer communities
• Physical product • Indirect
channel • Wholesale
• Existing market Polymer
manufacturers, Biotech
companies,Surfactant
manufacturers
• New market -Novel bio-
plastic companies?
• Multi-sided market?
• Sell bio-based monomers• Added value pricing based on
customization of products• Licensing?
• Fixed – Capital• Variable – Manufacturing, Bio-
mass
Business Model Canvas 2.0
- Bio-mass suppliers
- Contractual scale-up
- Technology providers
-Utility providers
• Production, yield, quality• Match customer’s
product specs
• Manufacturin
g facility• IP
• Human resources,
capital• SRI (Market
Info)
Problem - Non-renewable feedstock
Solution – Bio-based,
sustainable replacement
Features - Bi-functional,
customizable• ‘Drop-in’
monomers• Diacids (chain length: C10-C16)
• New functionalities (cyanide, amine)
• Co-create value
proposition• Customer goodwill and
trust• Customer communities
• Physical product • Indirect
channel • Wholesale
• Existing market Polymer
manufacturers, Biotech
companies,Surfactant
manufacturers
• New market -Novel bio-
plastic companies?
• Multi-sided market?
• State funding, SBIR funding • Sell bio-based monomers• Added value pricing based on
customization of products• Licensing
• Fixed – Capital• Variable – Manufacturing, Bio-
mass
Business Model Canvas 3.0
- Bio-mass suppliers
- Contractual scale-up
- Technology providers
-Utility providers
• Production, yield, quality• Match customer’s
product specs
• Manufacturin
g facility• IP
• Human resources,
capital• SRI IHS
(Market Info)
Problem - Non-renewable feedstock
Solution – Bio-based,
sustainable replacement
Features - Bi-functional,
customizable• ‘Drop-in’
monomers• Diacids (chain length: C10-C16)
• New functionalities (cyanide, amine)
• Co-create value
proposition• Customer goodwill and
trust• Customer communities
• Physical product • Indirect
channel • Wholesale
• Existing market Polymer
manufacturers, Biotech
companies,Surfactants,
Home & Personal Care
sector
• New market -Novel bio-
plastic companies?
• Multi-sided market?
• State funding, SBIR funding • Sell bio-based monomers• Added value pricing based on
customization of products• Licensing
• Fixed – Capital• Variable – Manufacturing, Bio-
mass
Business Model Canvas 4.0
Business Model Canvas 4.3
• Production, yield, quality• Match customer’s
product specs
Problem - Non-renewable feedstock
Solution – Bio-based, sustainable
replacement• Local supply of
surfactant raw-material
• Avoidance of single material sourcing (petro)• Green
Features - Bi-functional,
customizable• ‘Drop-in’
monomers
• Sell bio-based monomers• Added value pricing based on
customization of products• Licensing
• Manufacturing
facility• IP
• Human resources,
capital• IHS (Market
Info)
- Bio-mass suppliers
- Contractual scale-up
- Technology providers
-Utility providers
Existing markets• Polymer
manufacturers
• Biotech companies
Customer in value chainFormulator companies
Existing market sectors
• Surfactants
• Home & Personal Care sector
• Fixed – Capital• Variable – Manufacturing, Bio-mass
• Co-create value
proposition• Customer goodwill and
trust• Customer communities
• Physical product
•Indirect channel • Wholesale
Distributors
Business Model Canvas 5.0
• Production, yield, quality• Match customer’s
product specs
Problem - Non-renewable feedstock
Solution – Bio-based, sustainable
replacement•Regional supply of surfactant raw-
material• Avoidance of
single material sourcing (petro)• Green
Features - Bi-functional,
customizable• ‘Drop-in’
monomers
• Sell bio-based monomers• Added value pricing based on
customization of products• Licensing
• Manufacturing
facility• IP
• Human resources,
capital• IHS (Market
Info)
- Bio-mass suppliers
- Contractual scale-up
- Technology providers
-Utility providers
Existing markets• Polymer
manufacturers
• Biotech companies
Customer in value chainFormulator companies
Existing market sectors
• Surfactants
• Home & Personal Care sector
• Fixed – Capital• Variable – Manufacturing, Bio-mass
• Co-create value
proposition• Customer goodwill and
trust• Customer communities
• Physical product
•Indirect channel • Wholesale
Distributors
Business Model Canvas 6.0
• Production, yield, quality• Match customer’s
product specs
Problem - Non-renewable feedstock
Solution – Bio-based, sustainable
replacement•Regional supply of surfactant raw-
material• Avoidance of
single material sourcing (petro)• Green• High-
performance
Features - Bi-functional,
customizable• ‘Drop-in’
monomers
• Sell bio-based monomers• Added value pricing based on
customization of products• Licensing
• Manufacturing
facility• IP
• Human resources,
capital• IHS (Market
Info)
- Bio-mass suppliers
- Contractual scale-up
- Technology providers
-Utility providers
Customer in value chainFormulator companies
Existing market sectors
• Surfactants
• Lubricants
• Home & Personal Care sector
• Fixed – Capital• Variable – Manufacturing, Bio-mass
•Co-create value proposition
• Customer goodwill and trust• Customer communities
• Trade-shows, PR• Conferences,
surveys
• Physical product
•Indirect channel • Wholesale
Distributors
Business Model Canvas 7.0
• Production, yield, quality• Match customer’s
product specs • Constant
innovation
Problem - Non-renewable feedstock
Solution – Bio-based, sustainable
replacement•Regional supply of surfactant raw-
material• Avoidance of
single material sourcing (petro)• Green• High-
performance
Features - Bi-functional,
customizable• ‘Drop-in’
monomers• Sell bio-based monomers• Added value pricing based on
customization of products• Create demand by partnering with
Surfactant Users and then sell to Formulators• Licensing
• Manufacturing
facility• IP
• Human resources,
capital• IHS (Market
Info)
- Cheapest bio-mass suppliers
- Contractual scale-up
- Technology providers
-Utility providers
- Surfactant Users (P&G)
Customer in value chainFormulator companies
Existing market sectors
• Surfactants
• Lubricants
• Home & Personal Care sector
• Fixed – Capital• Variable – Manufacturing, Bio-mass
•Co-create value proposition
• Customer goodwill and trust• Customer communities
• Trade-shows, PR• Conferences,
surveys
• Physical product
•Indirect channel • Wholesale
Distributors
Business Model Canvas 8.0
• Production, yield, quality• Match customer’s
product specs • Constant
innovation
Problem - Non-renewable feedstock
Solution – Bio-based, sustainable
replacement•Regional supply of surfactant raw-
material• Avoidance of
single material sourcing (petro)• Green• High-
performance
Features - Bi-functional,
customizable• ‘Drop-in’
monomers
• Sell bio-based monomers• Create demand by partnering with
Surfactant Users and then sell to Formulators• Licensing
• Manufacturing
facility• IP
• Human resources,
capital• IHS (Market
Info)
-Market Research Agencies
- Start-up incubators
Cheapest bio-mass suppliers
- Contractual scale-up
- Technology providers
-Utility providers
- Surfactant Users (P&G)
Customer in value chainFormulator companies
Existing market sectors
• Surfactants
• Lubricants
• Home & Personal Care sector
• Fixed – Capital• Variable – Manufacturing, Bio-mass
•Co-create value proposition
• Customer goodwill and trust• Customer communities
• Trade-shows, PR• Conferences,
surveys
• Physical product
•Indirect channel • Wholesale
Distributors