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Management of G.I. Disorders
G.I. DISEASES
• Peptic ulcer• Gastric cancer• Gastritis• Pancreatitis• Chronic benign gastric ulcer• Zollinger-ellison syndrome• Post gastrectomy syndrome
PEPTIC ULCER
What?
• Characterized by ulcerating mucosal lesions in upper G.I tract due to acid & pepsin attack
• Chronic inflammatory condition
Where?
• Stomach, duodenum
ETIOLOGY
• H.pylori infection• Hyperacidity• Drugs (NSAIDS & Corticosteroids)• Cigarette smoking• Alcohol• Stress• Rapid gastric emptying
SIGN & SYMPTOM
• Stomach ulcer• Anorexia• Heartburn• Epigastric pain• Nausea • Vomiting• Duodenal ulcer• Tenderness• Burning• Aching at belly button• Relieved by food intake & antacid
• HELICOBACTER PYLORI
•Most common infection in world (20%)
•10% men, 4% women
•Positive in 70-100% PUD patients
DIAGNOSIS
• Endoscopy• Barium meal (contrast x-
ray)• Biopsy (bacteria &
malignancy)• Culture (h.pylori)
COMPLICATIONS
Hemorrhage Due to ulcers eroding blood vessels
Penetration into adjacent structuresPancrease, biliary tract, liver colon
Perforation
DRUG THERAPY/TREATMENT
Provide pain relief(antacid + mucosal protector)
Eradicate H.Pylori infection(2 antibiotics + acid suppressor)
Surgery if,Perforated and overflowed in abdomenObstruction because of swellingNon responsive to medication
MANAGEMENT
• Avoid taking spicy, oily food intake• Stop smoking• Regular diet• Avoid NSAIDS
GASTRIC ULCER vs PEPTIC ULCER
• Clinical features1. Peptic Ulcer (most common)• Burning right epigastric pain 90 min to 3 hrs. after
meal• Often nocturnal• Relieved by food intake (as pyloric antrum closes,
preventing the gastric juice from passing to duo.)2. Gastric Ulcer• Burning left epigastric pain within 1 hr of food
intake• Anorexia, food aversion, • Weight loss in 40%• Unrelated to food
Jayesh Raut: 23Dhruvit Kalathiya: 22Shrutee Acharya: 21
Submitted to:
Dr. Sheetal madam
Presented by: