Quantitative Drug Testing Workgroup Notice (New, Revised and Deleted Codes for 2015)
The following table is a listing of the new, revised, and deleted codes in the Drug Testing, Therapeutic Drug Assay, and Chemistry sections that will be effective January 1, 2015.
If an applicant or other interested party believes an action of the CPT Editorial Panel was in error, that individual or entity may submit a code change application to the CPT Editorial Panel. The application and instructions may be obtained by visiting the AMA website. An “interested party” is an individual or entity that may potentially be impacted by the Panel’s decision, regardless of whether they participated in the Panel’s original consideration of the matter.
Note: Permanent code numbers are not assigned, nor exact wording finalized, until just prior to publication. Codes that contain an 'X' (eg, 1002X4, 234X2X, 0301XT) are placeholder codes that are intended, through the first three digits, to give readers an idea of the proposed placement in the code set of the potential code changes. These codes are not used for claims reporting and will be removed and not retained when the final CPT Datafiles are distributed on August 31st of each year. To report the services for 'X' codes, please refer to the actual codes as they appear in the CPT Datafiles publication distributed on August 31st of each year.
Detailed information regarding these codes including, guidelines, parenthetical notes, rationales and clinical examples will be available with the August 31
st release of the CPT code set data files and
subsequent educational materials, including CPT Changes 2015: An Insider’s View. You may learn more about obtaining these materials by visiting amastore.com.
▲80100 Drug screen, qualitative; multiple drug classes chromatographic method, each procedure
80101 single drug class method (eg, immunoassay, enzyme assay), each drug class
(For qualitative analysis by multiplexed screening kit for multiple drugs or drug classes, use 80104)
#80104 multiple drug classes other than chromatographic method, each procedure
80102 Drug confirmation, each procedure
80103 Tissue preparation for drug analysis
801XXX1 Drug screen, any number of drug classes from Drug Class List A; any number of non-TLC devices or procedures, (eg, immunoassay) capable of being read by direct optical observation including instrumented-assisted when performed (eg, dipsticks, cups, cards, cartridges), per date of service
801XX2A single drug class method, by instrumented test systems (eg, discrete multichannel chemistry analyzers utilizing immunoassay or enzyme assay), per date of service
801XX4A Drug screen, presumptive, single drug class from Drug Class List B, by immunoassay (eg, ELISA) or non-TLC chromatography without mass spectrometry (eg, GC, HPLC), each procedure
801XXX6 Drug screen, any number of drug classes, presumptive, single or multiple drug class method; thin layer chromatography procedure(s) (TLC)(eg, acid, neutral, alkaloid plate), per date of service
801XXX7 not otherwise specified presumptive procedure (eg, TOF, MALDI, LDTD, DESI, DART), each procedure
801XY1 Alcohols
801XY2 Alcohol biomarkers; 1 to 2
Quantitative Drug Testing Workgroup Notice (New, Revised and Deleted Codes for 2015)
801XY3 3 or more
801XY44 Alkaloids, not otherwise specified
801XY18 Amphetamines, 1 to 2
801XY19 3 to 4
801XY20 5 or more
801XY44A Anabolic steroids 1-2
801XY44B 3 or more
801XY28 Analgesics, non-opioid; 1 to 2 drugs
801XY29 3 to 5
801XY30 6 or more
801XY22 Antidepressants, serotonergic class; 1 to 2 drugs
801XY23 3 to 5
801XY24 6 or more
801XY25 Antidepressants, tricyclic and other cyclicals; 1 to 2 drugs
801XY26 3 to 5
801XY27 6 or more
801XY27A Antidepressants, not otherwise specified
801XY34 Antiepileptics, not otherwise specified; 1 to 3 drugs
801XY35 4 to 6
801XY36 7 or more
801XY31 Antispychotics, not otherwise specified; 1 to 3 drugs
801XY32 4 to 6
801XY33 7 or more
801XY4 Barbiturates
801XY5 Benzodiazepines; 1-12
801XY6 13 or more
801XY12 Buprenorphine
801XY37 Cannabinoids, natural
801XY38 Cannabinoids, synthetic 1 to 3
801XY39 4 to 6
801XY40 7 or more
801XY43 Cocaine
801XY13 Fentanyl
801XY13B Gabapentin, non-blood
801XY9 Heroin metabolite
Quantitative Drug Testing Workgroup Notice (New, Revised and Deleted Codes for 2015)
801XY9A Ketamine and norketamine
801XY10 Methadone
801XY17B Methylenedioxyamphetamines (MDA, MDEA, MDMA)
801XY17C Methylphenidate
801XY7 Opiates, one or more
801XY15 Opioids and opiate analogs; 1 to 2
801XY16 3 to 4
801XY17 5 or more
801XY8 Oxycodone
801XY13A Pregabalin
801XY7A Propoxyphene
801XY7B Sedative hypnotics (non-benzodiazepines)
801XY14 Skeletal muscle relaxants; 1-2
801XX14A 3 or more
801XY41 Stimulants, synthetic
801XY42 Tapentadol
801XY48 Tramadol
801XY17A Stereoisomer (enantiomer) analysis, single drug class
801XY45 Drug(s) or substance(s), definitive, qualitative or quantitative, not otherwise specified; 1 to 3
801XY46 4 to 6
801XY47 7 or more
80152 Amitriptyline
80154 Benzodiazepines
80160 Desipramine
▲80162 Digoxin; total
80XXX13 free
▲80164 Dipropylacetic acid (valproic acid) Valproic acid (dipropylacetic acid); total
80XXX11 free
80166 Doxepin
▲80171 Gabapentin, whole blood, serum or plasma
80172 Gold
80174 Imipramine
80182 Nortriptyline
#84228 Quinine
Quantitative Drug Testing Workgroup Notice (New, Revised and Deleted Codes for 2015)
80196 Salicylate
▲80299 Quantitation of therapeutic drug, not elsewhere specified
82000 Acetaldehyde, blood
82003 Acetaminophen
82055 Alcohol (ethanol); any specimen except breath
82101 Alkaloids, urine, quantitative
82145 Amphetamine or metaamphetamine
82205 Barbiturates, not elsewhere specified
82520 Cocaine or metabolite
▲82541 Column chromatography/mass spectrometry (eg, GC/MS, or HPLC/MS), non-drug analyte not elsewhere specified; qualitative, single stationary and mobile phase
▲82544 stable isotope dilution, multiple analytes, quantitative, single stationary and mobile phase
82646 Dihydrocodeinone
82649 Dihydromorphinone
82651 Dihydrotestosterone (DHT)
82654 Dimethadione
82666 Epiandrosterone
82690 Ethchlorvynol
82742 Flurazepam
82980 Glutethimide
83840 Methadone
83858 Methsuximide
83887 Nicotine
83925 Opiate(s), drug and metabolites, each procedure
84022 Phenothiazine
▲84600 Volatiles (eg, acetic anhydride, carbon tetrachloride, dichloroethane, dichloromethane, diethylether, isopropyl alcohol, methanol)
Quantitative Drug Testing Workgroup Notice (New, Revised and Deleted Codes for 2015)
Drug Class A
Alcohol (Ethanol)
Amphetamines
Barbiturates
Benzodiazepines
Buprenorphine
Cocaine metabolite
Heroin metabolite (6-monoacetylmorphine)
Methadone
Methadone metabolite (EDDP)
Methamphetamine
Methaqualone
Methylenedioxymethamphetamine (MDMA)
Opiates
Oxycodone
Phencyclidine
Propoxyphene
Tetrahydrocannabinol (THC) metabolites (marijuana)
Tricyclic Antidepressants
Drug Class B
Acetaminophen
Carisoprodol/Meprobamate
Ethyl Glucuronide
Fentanyl
Ketamine
Meperidine
Methylphenidate
Nicotine/Cotinine
Salicylate
Synthetic Cannabinoids
Tapentadol
Tramadol
Zolpidem
Not otherwise specified
Quantitative Drug Testing Workgroup Notice (New, Revised and Deleted Codes for 2015)
Definitive Drug Classes Listing
Codes Classes Drugs
801XY1 Alcohol(s) Acetone, Ethanol, ethchlorvynol, ethylene glycol, isopropanol, isopropyl alcohol, methanol
801XY2-801XY3
Alcohol Biomarkers
Ethanol conjugates (ethyl glucuronide [ETG], ethyl sulfate [ETS], fatty acid ethyl esters, phosphatidylethanol)
801XY44 Alkaloids, not otherwise specified
7-Hydroxymitragynine, atropine, cotinine, lysergic acid diethylamide (LSD), mescaline, mitragynine, nicotine, psilocin, psilocybin, scopolamine
801XY18-801XY20
Amphetamines Amphetamine, ephedrinelisdexamphetamine, methamphetamine, phentermine, phenylpropanolamine, pseudoephedrine
801XY44A-801XY44B
Anabolic steroids 1-Androstenediol, 1-androstenedione, 1-testosterone, 4-hydroxy-testosterone, 6oxo, 19-norandrostenedione, androstenedione, androstanolone, bolandiol, bolasterone, boldenone, boldione, calusterone, clostebol, danazol, dehydrochlormethyltestosterone, dihydrotestosterone, drostanolone, epiandrosterone, epitestosterone, fluoxymesterone, furazabol, mestanolone, mesterolone, methandienone, methandriol, methenolone, methydienolone, methyl-1-testosterone, methylnortestosterone, methyltestosterone, mibolerone, nandrolone, norbolethone, norclostebol, norethandrolone, norethindrone, oxabolone, oxandrolone, oxymesterone, oxymetholone, stanozolol, stenbolone, tibolone, trenbolone, zeranol
801XY28-801XY30
Analgesics, non-opioid Acetaminophen, diclofenac ibuprofen, ketoprofen, naproxen, oxaprozin, salicylate
801XY22-801XY24
Antidepressants, serotonergic class
Citalopram, duloxetine, escitalopram, fluoxetine, fluvoxamine, paroxetine, sertraline
801XY25-801XY27
Antidepressants, Tricyclic and other cyclicals
Amitriptyline, amoxapine, clomipramine, demexiptiline, desipramine, doxepin, imipramine, maprotiline, mirtazpine, nortriptyline, protriptyline,
801XY27A Antidepressants, not otherwise specified
Bupropion, desyenlafaxine, isocarboxazid, nefazodone, phenelzine, selegiline, tranylcypromine, trazodone, venlafaxine
801XY34-801XY36
Antiepileptics Carbamazepine, clobazam, diamethadione, ethosuximide, ezogabine, lamotrigine, levetiracetam, methsuximide, oxcarbazepine, phenytoin, primidone, rufinamide, tiagabine, topiramate, trimethadione, valproic acid, zonisamide
Quantitative Drug Testing Workgroup Notice (New, Revised and Deleted Codes for 2015)
801XY31-801XY33
Antipsychotics Aripiprazole, chlorpromazine, clozapine, fluphenazine, haloperidol, loxapine, mesoridazine, molindone, olanzapine, paliperidone, perphenazine, phenothiazine, pimozide, prochlorperazine, quetiapine, risperidone, trifluoperazine, thiothixene, thoridazine, ziprasidone
801XY4 Barbiturates Amobarbital, aprobarbital, butalbital, cyclobarbital, mephobarbital, pentobarbital, phenobarbital, secobarbital, talbutal, thiopental
801XY5, 801XY6
Benzodiazepines Alprazolam, chlordiazepoxide, clonazepam, clorazepate, diazepam, estazolam, flunitrazepam, flurazepam, halazepamlorazepammidazolam, nitrazepam, nordazepam, oxazepam, prazepam, quazepam, temazepam
801XY12 Buprenorphine Buprenorphine
801XY37 Cannabinoids, natural Marijuana, dronabinol carboxy-THC
801XY38-801XY40
Cannabinoids, synthetic CP-47,497, CP497 C8-homolog, JWH-018 and AM678, JWH-073, JWH-019, JWH-200, JWH-210, JWH-250, JWH-081, JWH-122, HWH-398, AM-2201, AM-694, SR-19 and RCS-4, SR-18 and RCS-8, JWH-203, UR-144, XLR-11, MAM-2201, AKB-48.
801XY43 Cocaine Benzoylecgonine, cocaethylene, cocaine, ecgonine methyl ester, norcocaine
801XY13 Fentanyls Acetylfentanyl, alfentanil, fentanyl, remifentanil, sufentanil
801XY13B Gabapentin, non-blood gabapentin
801XY9 Heroin metabolite 6-acetylmorphine , acetylcodeine , diacetylmorphine
801XY7B Hypnotics, sedative (non-benzodiazepines)
See Sedative Hypnotics
801XY9A Ketamine and Norketamine Ketamine, norketamine
801XY10 Methadone Methadone and EDDP
801XY17B Methylenedioxyamphetamines MDA, MDEA, MDMA
Staff Note: AMA Staff mistakenly mislabeled assignment of “X” code to this material. The above reflects correction.
801XY17C Methylphenidate Methylphenidate, ritalinic acid
801XY9A Norketamine – see Ketamine
801XY7B Non-Benzodiazepines – see Hypnotics, sedative
801XY7 Opiates Codeine, dihydrocodeine, hydrocodone, hydromorphone, morphine
801XY15-801XY17
Opioids and opiate analogs Butorphanol, desomorphine, dextromethorphan, dextrorphan, levorphanol, meperidine, naloxone, naltrexone, normeperidine, pentazocine,
801XY8 Oxycodone Oxycodone, oxymorphone
801XY21 Phencyclidine Phencyclidine
801XY13A Pregabalin Pregabalin
801XY7A Propoxyphene Norpropoxyphene, propoxyphene
Quantitative Drug Testing Workgroup Notice (New, Revised and Deleted Codes for 2015)
801XY7B Sedative Hypnotics Eszopiclone, Zaleplon, Zolpidem
801XY14-801XY14A
Skeletal muscle relaxants Baclofen, carisoprodol, cyclobenzaprine, metaxalone, methocarbamol, orphenadrine, tizanidide.
801XY41 Stimulants, synthetic 2C-B, 2C-E, 2C-I, 2C-H, 3TFMPP, 4-methylethcathinone, alpha-PVP, benzylpiperazine, bromodragonfly, cathinone, m-CPP, MDPBP, MDPPP, MDPV, mephedrone, methcathinone, methylone, phenethylamines, salvinorin, tryptamines
801XY42 Tapentadol Tapentadol
801XY48 Tramadol Tramadol