Quantitative Drug Testing Workgroup Notice (New, Revised ... Drug Testing Workgroup Notice ... Quantitative Drug Testing Workgroup Notice (New, Revised and Deleted Codes for 2015) ... olanzapine, paliperidone ...

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  • Quantitative Drug Testing Workgroup Notice (New, Revised and Deleted Codes for 2015)

    The following table is a listing of the new, revised, and deleted codes in the Drug Testing, Therapeutic Drug Assay, and Chemistry sections that will be effective January 1, 2015.

    If an applicant or other interested party believes an action of the CPT Editorial Panel was in error, that individual or entity may submit a code change application to the CPT Editorial Panel. The application and instructions may be obtained by visiting the AMA website. An interested party is an individual or entity that may potentially be impacted by the Panels decision, regardless of whether they participated in the Panels original consideration of the matter.

    Note: Permanent code numbers are not assigned, nor exact wording finalized, until just prior to publication. Codes that contain an 'X' (eg, 1002X4, 234X2X, 0301XT) are placeholder codes that are intended, through the first three digits, to give readers an idea of the proposed placement in the code set of the potential code changes. These codes are not used for claims reporting and will be removed and not retained when the final CPT Datafiles are distributed on August 31st of each year. To report the services for 'X' codes, please refer to the actual codes as they appear in the CPT Datafiles publication distributed on August 31st of each year.

    Detailed information regarding these codes including, guidelines, parenthetical notes, rationales and clinical examples will be available with the August 31

    st release of the CPT code set data files and

    subsequent educational materials, including CPT Changes 2015: An Insiders View. You may learn more about obtaining these materials by visiting amastore.com.

    80100 Drug screen, qualitative; multiple drug classes chromatographic method, each procedure

    80101 single drug class method (eg, immunoassay, enzyme assay), each drug class

    (For qualitative analysis by multiplexed screening kit for multiple drugs or drug classes, use 80104)

    #80104 multiple drug classes other than chromatographic method, each procedure

    80102 Drug confirmation, each procedure

    80103 Tissue preparation for drug analysis

    801XXX1 Drug screen, any number of drug classes from Drug Class List A; any number of non-TLC devices or procedures, (eg, immunoassay) capable of being read by direct optical observation including instrumented-assisted when performed (eg, dipsticks, cups, cards, cartridges), per date of service

    801XX2A single drug class method, by instrumented test systems (eg, discrete multichannel chemistry analyzers utilizing immunoassay or enzyme assay), per date of service

    801XX4A Drug screen, presumptive, single drug class from Drug Class List B, by immunoassay (eg, ELISA) or non-TLC chromatography without mass spectrometry (eg, GC, HPLC), each procedure

    801XXX6 Drug screen, any number of drug classes, presumptive, single or multiple drug class method; thin layer chromatography procedure(s) (TLC)(eg, acid, neutral, alkaloid plate), per date of service

    801XXX7 not otherwise specified presumptive procedure (eg, TOF, MALDI, LDTD, DESI, DART), each procedure

    801XY1 Alcohols

    801XY2 Alcohol biomarkers; 1 to 2


  • Quantitative Drug Testing Workgroup Notice (New, Revised and Deleted Codes for 2015)

    801XY3 3 or more

    801XY44 Alkaloids, not otherwise specified

    801XY18 Amphetamines, 1 to 2

    801XY19 3 to 4

    801XY20 5 or more

    801XY44A Anabolic steroids 1-2

    801XY44B 3 or more

    801XY28 Analgesics, non-opioid; 1 to 2 drugs

    801XY29 3 to 5

    801XY30 6 or more

    801XY22 Antidepressants, serotonergic class; 1 to 2 drugs

    801XY23 3 to 5

    801XY24 6 or more

    801XY25 Antidepressants, tricyclic and other cyclicals; 1 to 2 drugs

    801XY26 3 to 5

    801XY27 6 or more

    801XY27A Antidepressants, not otherwise specified

    801XY34 Antiepileptics, not otherwise specified; 1 to 3 drugs

    801XY35 4 to 6

    801XY36 7 or more

    801XY31 Antispychotics, not otherwise specified; 1 to 3 drugs

    801XY32 4 to 6

    801XY33 7 or more

    801XY4 Barbiturates

    801XY5 Benzodiazepines; 1-12

    801XY6 13 or more

    801XY12 Buprenorphine

    801XY37 Cannabinoids, natural

    801XY38 Cannabinoids, synthetic 1 to 3

    801XY39 4 to 6

    801XY40 7 or more

    801XY43 Cocaine

    801XY13 Fentanyl

    801XY13B Gabapentin, non-blood

    801XY9 Heroin metabolite

  • Quantitative Drug Testing Workgroup Notice (New, Revised and Deleted Codes for 2015)

    801XY9A Ketamine and norketamine

    801XY10 Methadone

    801XY17B Methylenedioxyamphetamines (MDA, MDEA, MDMA)

    801XY17C Methylphenidate

    801XY7 Opiates, one or more

    801XY15 Opioids and opiate analogs; 1 to 2

    801XY16 3 to 4

    801XY17 5 or more

    801XY8 Oxycodone

    801XY13A Pregabalin

    801XY7A Propoxyphene

    801XY7B Sedative hypnotics (non-benzodiazepines)

    801XY14 Skeletal muscle relaxants; 1-2

    801XX14A 3 or more

    801XY41 Stimulants, synthetic

    801XY42 Tapentadol

    801XY48 Tramadol

    801XY17A Stereoisomer (enantiomer) analysis, single drug class

    801XY45 Drug(s) or substance(s), definitive, qualitative or quantitative, not otherwise specified; 1 to 3

    801XY46 4 to 6

    801XY47 7 or more

    80152 Amitriptyline

    80154 Benzodiazepines

    80160 Desipramine

    80162 Digoxin; total

    80XXX13 free

    80164 Dipropylacetic acid (valproic acid) Valproic acid (dipropylacetic acid); total

    80XXX11 free

    80166 Doxepin

    80171 Gabapentin, whole blood, serum or plasma

    80172 Gold

    80174 Imipramine

    80182 Nortriptyline

    #84228 Quinine

  • Quantitative Drug Testing Workgroup Notice (New, Revised and Deleted Codes for 2015)

    80196 Salicylate

    80299 Quantitation of therapeutic drug, not elsewhere specified

    82000 Acetaldehyde, blood

    82003 Acetaminophen

    82055 Alcohol (ethanol); any specimen except breath

    82101 Alkaloids, urine, quantitative

    82145 Amphetamine or metaamphetamine

    82205 Barbiturates, not elsewhere specified

    82520 Cocaine or metabolite

    82541 Column chromatography/mass spectrometry (eg, GC/MS, or HPLC/MS), non-drug analyte not elsewhere specified; qualitative, single stationary and mobile phase

    82544 stable isotope dilution, multiple analytes, quantitative, single stationary and mobile phase

    82646 Dihydrocodeinone

    82649 Dihydromorphinone

    82651 Dihydrotestosterone (DHT)

    82654 Dimethadione

    82666 Epiandrosterone

    82690 Ethchlorvynol

    82742 Flurazepam

    82980 Glutethimide

    83840 Methadone

    83858 Methsuximide

    83887 Nicotine

    83925 Opiate(s), drug and metabolites, each procedure

    84022 Phenothiazine

    84600 Volatiles (eg, acetic anhydride, carbon tetrachloride, dichloroethane, dichloromethane, diethylether, isopropyl alcohol, methanol)

  • Quantitative Drug Testing Workgroup Notice (New, Revised and Deleted Codes for 2015)

    Drug Class A

    Alcohol (Ethanol)





    Cocaine metabolite

    Heroin metabolite (6-monoacetylmorphine)


    Methadone metabolite (EDDP)



    Methylenedioxymethamphetamine (MDMA)





    Tetrahydrocannabinol (THC) metabolites (marijuana)

    Tricyclic Antidepressants

    Drug Class B



    Ethyl Glucuronide







    Synthetic Cannabinoids




    Not otherwise specified

  • Quantitative Drug Testing Workgroup Notice (New, Revised and Deleted Codes for 2015)

    Definitive Drug Classes Listing

    Codes Classes Drugs

    801XY1 Alcohol(s) Acetone, Ethanol, ethchlorvynol, ethylene glycol, isopropanol, isopropyl alcohol, methanol


    Alcohol Biomarkers

    Ethanol conjugates (ethyl glucuronide [ETG], ethyl sulfate [ETS], fatty acid ethyl esters, phosphatidylethanol)

    801XY44 Alkaloids, not otherwise specified

    7-Hydroxymitragynine, atropine, cotinine, lysergic acid diethylamide (LSD), mescaline, mitragynine, nicotine, psilocin, psilocybin, scopolamine


    Amphetamines Amphetamine, ephedrinelisdexamphetamine, methamphetamine, phentermine, phenylpropanolamine, pseudoephedrine


    Anabolic steroids 1-Androstenediol, 1-androstenedione, 1-testosterone, 4-hydroxy-testosterone, 6oxo, 19-norandrostenedione, androstenedione, androstanolone, bolandiol, bolasterone, boldenone, boldione, calusterone, clostebol, danazol, dehydrochlormethyltestosterone, dihydrotestosterone, drostanolone, epiandrosterone, epitestosterone, fluoxymesterone, furazabol, mestanolone, mesterolone, methandienone, methandriol, methenolone, methydienolone, methyl-1-testosterone, methylnortestosterone, methyltestosterone, mibolerone, nandrolone, norbolethone, norclostebol, norethandrolone, norethindrone, oxabolone, oxandrolone, oxymesterone, oxymetholone, stanozolol, stenbolone, tibolone, trenbolone, zeranol


    Analgesics, non-opioid Acetaminophen, diclofenac ibuprofen, ketoprofen, naproxen, oxaprozin, salicylate


    Antidepressants, serotonergic class

    Citalopram, duloxetine, escitalopram, fluoxetine, fluvoxamine, paroxetine, sertraline


    Antidepressants, Tricyclic and other cyclicals

    Amitriptyline, amoxapine, clomipramine, demexiptiline, desipramine, doxepin, imipramine, maprotiline, mirtazpine, nortriptyline, protriptyline,

    801XY27A Antidepressants, not otherwise specified

    Bupropion, desyenlafaxine, isocarboxazid, nefazodone, phenelzine, selegiline, tranylcypromine, trazodone, venlafaxine


    Antiepileptics Carbamazepine, clobazam, diamethadione, ethosuximide, ezogabine, lamotrigine, levetiracetam, methsuximide, oxcarbazepine, phenytoin, primidone, rufinamide, tiagabine, topiramate, trimethadione, valproic acid, zonisamide

  • Quantitative Drug Testing Workgroup Notice (New, Revised and Deleted Codes for 2015)


    Antipsychotics Aripiprazole, chlorpromazine, clozapine, fluphenazine, haloperidol, loxapine, mesoridazine, molindone, olanzapine, paliperidone, perphenazine, phenothiazine, pimozide, prochlorperazine, quetiapine, risperidone, trifluoperazine, thiothixene, thoridazine, ziprasidone

    801XY4 Barbiturates Amobarbital, aprobarbital, butalbital, cyclobarbital, mephobarbital, pentobarbital, phenobarbital, secobarbital, talbutal, thiopental

    801XY5, 801XY6

    Benzodiazepines Alprazolam, chlordiazepoxide, clonazepam, clorazepate, diazepam, estazolam, flunitrazepam, flurazepam, halazepamlorazepammidazolam, nitrazepam, nordazepam, oxazepam, prazepam, quazepam, temazepam

    801XY12 Buprenorphine Buprenorphine

    801XY37 Cannabinoids, natural Marijuana, dronabinol carboxy-THC


    Cannabinoids, synthetic CP-47,497, CP497 C8-homolog, JWH-018 and AM678, JWH-073, JWH-019, JWH-200, JWH-210, JWH-250, JWH-081, JWH-122, HWH-398, AM-2201, AM-694, SR-19 and RCS-4, SR-18 and RCS-8, JWH-203, UR-144, XLR-11, MAM-2201, AKB-48.

    801XY43 Cocaine Benzoylecgonine, cocaethylene, cocaine, ecgonine methyl ester, norcocaine

    801XY13 Fentanyls Acetylfentanyl, alfentanil, fentanyl, remifentanil, sufentanil

    801XY13B Gabapentin, non-blood gabapentin

    801XY9 Heroin metabolite 6-acetylmorphine , acetylcodeine , diacetylmorphine

    801XY7B Hypnotics, sedative (non-benzodiazepines)

    See Sedative Hypnotics

    801XY9A Ketamine and Norketamine Ketamine, norketamine

    801XY10 Methadone Methadone and EDDP

    801XY17B Methylenedioxyamphetamines MDA, MDEA, MDMA

    Staff Note: AMA Staff mistakenly mislabeled assignment of X code to this material. The above reflects correction.

    801XY17C Methylphenidate Methylphenidate, ritalinic acid

    801XY9A Norketamine see Ketamine

    801XY7B Non-Benzodiazepines see Hypnotics, sedative

    801XY7 Opiates Codeine, dihydrocodeine, hydrocodone, hydromorphone, morphine


    Opioids and opiate analogs Butorphanol, desomorphine, dextromethorphan, dextrorphan, levorphanol, meperidine, naloxone, naltrexone, normeperidine, pentazocine,

    801XY8 Oxycodone Oxycodone, oxymorphone

    801XY21 Phencyclidine Phencyclidine

    801XY13A Pregabalin Pregabalin

    801XY7A Propoxyphene Norpropoxyphene, propoxyphene

  • Quantitative Drug Testing Workgroup Notice (New, Revised and Deleted Codes for 2015)

    801XY7B Sedative Hypnotics Eszopiclone, Zaleplon, Zolpidem


    Skeletal muscle relaxants Baclofen, carisoprodol, cyclobenzaprine, metaxalone, methocarbamol, orphenadrine, tizanidide.

    801XY41 Stimulants, synthetic 2C-B, 2C-E, 2C-I, 2C-H, 3TFMPP, 4-methylethcathinone, alpha-PVP, benzylpiperazine, bromodragonfly, cathinone, m-CPP, MDPBP, MDPPP, MDPV, mephedrone, methcathinone, methylone, phenethylamines, salvinorin, tryptamines

    801XY42 Tapentadol Tapentadol

    801XY48 Tramadol Tramadol


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