Cat and DogPreventative Care and
Medicine II
Dr. N. Matthew Ellinwood, D.V.M., Ph.D.
January 18, 2012
IOWA STATE UNIVERSITY
COLLEGE OF AGRICULTURE AND LIFE SCIENCES
Distemper and Measles
• Cross reactive antibodies– First vaccine
Parvo
• Small DNA virus
• World wide pandemic in dog in late 1970’s
• Viral Enteritis
• Virus requires rapidly dividing cells
• GI and Immune tropism
• Maternal antibodies among most persistent
Parvo Continued
• Crypt morphology
• Prognosis
• Therapy
CAV1 and CAV2
• CAV-1– Cause of Infectious Canine Hepatitis– Very rare to see due to vaccinal prophylaxis– Can lead to chronic shedding and infection
• Kidney and liver
– Blue eye
• CAV-2– Cause of infectious tracheobronchitis– Vaccinal strains yield cross reactive antibodies
Parainfluenza
• A cause of infectious tracheobronchitis– Paramyxovirus– No replication in macrophages– Local infection of upper respiratory tract– Vaccinal prevention
Corona
• Targets mature epithelial cells of mucousa• Usually a self limiting viral enteritis• Discovered in 1971 in an outbreak of military
dogs• Vaccinal prevention is incomplete• Death is rare
– Young pups with fluid loss
• Supportive care
Papillomatosis
• CPV cause papillomas– Young animals– Sites– Immunosuppressed animals
Versus
• Venereal transmissible tumor
Leptospira
• Environmental exposure
• Wildlife and rodent reservoir
• Shed in urine
• Water sources
• Type of dog at risk
• Regional serovars
• Vaccinal approach– Bactarin
Brucella
• Venereal
• Reportable
• Treatment difficulty/failure
• Clincial signs– Male– Female
Herpes
• Some characteristics of herpes virus
• 30% to 100% seropositivity
• Infection
• Adult
• Pups
• Prevention