Cat and DogPreventative Care and

Medicine II

Dr. N. Matthew Ellinwood, D.V.M., Ph.D.

January 18, 2012

IOWA STATE UNIVERSITY

COLLEGE OF AGRICULTURE AND LIFE SCIENCES

Distemper and Measles

• Cross reactive antibodies– First vaccine

Parvo

• Small DNA virus

• World wide pandemic in dog in late 1970’s

• Viral Enteritis

• Virus requires rapidly dividing cells

• GI and Immune tropism

• Maternal antibodies among most persistent

Parvo Continued

• Crypt morphology

• Prognosis

• Therapy

CAV1 and CAV2

• CAV-1– Cause of Infectious Canine Hepatitis– Very rare to see due to vaccinal prophylaxis– Can lead to chronic shedding and infection

• Kidney and liver

– Blue eye

• CAV-2– Cause of infectious tracheobronchitis– Vaccinal strains yield cross reactive antibodies

Parainfluenza

• A cause of infectious tracheobronchitis– Paramyxovirus– No replication in macrophages– Local infection of upper respiratory tract– Vaccinal prevention

Corona

• Targets mature epithelial cells of mucousa• Usually a self limiting viral enteritis• Discovered in 1971 in an outbreak of military

dogs• Vaccinal prevention is incomplete• Death is rare

– Young pups with fluid loss

• Supportive care

Papillomatosis

• CPV cause papillomas– Young animals– Sites– Immunosuppressed animals

Versus

• Venereal transmissible tumor

Leptospira

• Environmental exposure

• Wildlife and rodent reservoir

• Shed in urine

• Water sources

• Type of dog at risk

• Regional serovars

• Vaccinal approach– Bactarin

Brucella

• Venereal

• Reportable

• Treatment difficulty/failure

• Clincial signs– Male– Female

Herpes

• Some characteristics of herpes virus

• 30% to 100% seropositivity

• Infection

• Adult

• Pups

• Prevention