ZNZ SYMPOSIUM 2009 - UZH

ZNZ SYMPOSIUM 2009

11 September 2009 08.30 - 18.00

ETH Hönggerberg, Zurich Lecture Hall G1, Building HPH

Schafmattstr. 36 8093 Zürich

ZNZ Symposium 2009 - Neuroscience Center Zurich Friday, 11 September 2009

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OVERVIEW of the POSTER ABSTRACTS (listed by topics) DEVELOPMENT AND REGENERATION Poster Abstract number(s)

Group Leader Fritschy J.-M. 1 Hengartner M. 2-3 Lipp H. P 4 Raineteau O. 5-6 Schwab M. 7-8 Sommer L. 9 Stoeckli E. 10-14 Zimmermann D. 15 SYNAPTIC TRANSMISSION AND PLASTICITY Group Leader Fritschy J.-M. 16 Geber U. 17 Martin K. 18 Raineteau O. 19 Zeilhofer H.-U. 20-21 MOLECULAR AND CELLULAR NEUROSCIENCE Group Leader Fritschy J.-M. 22-23 Jessberger S. 24-29 Mansuy I. 30-31 Raineteau O. 32 Sommer L. 33 Suter U. 34-35 Weller M. 36-37 Wollscheid B. 38-39 ENDOCRINE REGULATION, NEUROIMMUNOLOGY Group Leader Becher B. 40-42 Fontana A. 43 Frei K. 44 Ullrich O. 45


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SENSORY SYSTEMS Poster Abstract number(s) Group Leader Chicca E. 46 Curt A. 47 Helmchen F. 48 Hess B. 49 Kampa B. 50 Liu S.-C. 51-52 Martin K. 53-54 Micera S. 55 Neuhauss S. 56-60 Pfeifer R. 61 Raineteau O. 62 Riener R. 63 Rudin M. 64 Straumann D. 65 MOTOR SYSTEMS Group Leader Courtine G. 66-70 Dietz V. 71-72 Eng K. 73 Gassert R. 74-76 Van Hedel H. 77-79 Kollias S. 80-81 Meyer-Heim A. 82-83 Riener R. 84-85 Scherberger H. 86 Schwab M. 87 Straumann D. 88 SLEEP AND SLEEP DISORDERS Group Leader Achermann P. 89-91 Huber R. 92-93 Landolt H.-P. 94 Sarnthein J. 95 Tobler I. 96


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NEURAL BASIS OF BEHAVIOR Poster Abstract number(s) Group Leader Feldon J. 97-98 Lehmann D. 99 Lipp H.-P. 100-101 Weber B. 102 Wolfer D. 103 COGNITIVE NEUROSCIENCE AND NEUROPSYCHOLOGY Group Leader Brandeis D. 104-107 Henke K. 108-110 Ishai A. 111-112 Jäncke L. 113-117 Jokeit H. 118 Martin E. 119-120 Meyer M. 121-122 Yee B. 123 AGING AND DISORDERS OF THE NERVOUS SYSTEM Group Leader Fry S. 124 Gerber U. 125 Jäncke L. 126-127 Knüsel I. 128-130 Konietzko U. 131-132 Linnebank M. 133 Nitsch R. 134-140 Riener R. 141 Sarnthein J. 142 Schurch B. 143-144 Stassen H. 145-147 Suter U. 148 Zaugg K. 149 COMPUTATION AND MODELING

Group Leader Douglas R. 150-152 Indiveri G. 153-158 Liu S.-C. 159-160 Stoop R. 161-163 Weber B. 164-165 Wolf M. 166


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BIOMEDICAL TECHNOLOGY AND IMAGING Poster Abstract number(s) Group Leader Courtine G. 167-168 Eng K. 169 Van Hedel H. 170-171 Helmchen F. 172-173 Meyer-Heim A. 174-175 Micera S. 176-178 Rudin M. 179-181 Weber B. 182-183 Wolf M. 184


5 Development and Regeneration

POSTER ABSTRACTS DEVELOPMENT AND REGENERATION Group Leader: JEAN-MARC FRITSCHY 1 The role of microvillar cells as a linker between degenerating sensory

neurons and stem cells: S. Pfister, J.-M. Fritschy, R. Elsaesser

Group Leader: MICHAEL HENGARTNER 2 Characterization of axon guidance genes acting in parallel to HSPGs in

C. elegans: R. Egli, S. Gysi, M. Hengartner

3 The function of ZFP-1/AF10 during C. elegans nervous system development: S. Gysi, R. Egli, L. Reh, C. Rhiner, M.O. Hengartner

Group Leader: HANS-PETER LIPP 4 Regulatory mechanisms of adult hippocampal neurogenesis in

laboratory and wild wood mice: differential response to physical exercise: F. Klaus, T. Hauser, H.P. Lipp, I. Amrein

Group Leader: OLIVIER RAINETEAU

5 Adult generation of glutamatergic olfactory bulb interneurons: M. Brill, J. Ninkovic, E. Winpenny, I. Ozen, C. Parras, F. Guillemot, O. Raineteau, M. Götz

6 Engineering of dominant active bHLH proteins that are resistant to

negative regulation by postnatal CNS anti-neurogenic cues: C. G. Geoffroy, J.A. Critchley, D. S. Castro, S. Ramelli, P. Descombes, F. Guillemot, O. Raineteau

Group Leader: MARTIN E. SCHWAB 7 Nogo-A influences angiogenesis and blood vessel morphology in the

developing CNS: T. Wälchli, V. Pernet, O. Weinmann, A. Ulmann-Schuler,


Development and Regeneration 6

C. Hintermüller, S. Heinzer, B. Tews, K. Gosh, D. Ingber, M. Stampanoni, E. Meyer, K. Frei, M. E. Schwab

8 Neuronal Nogo-A modulates growth and fasciculation of neurites in the

developing nervous system: M. M. Petrinovic, C. Duncan, D. Bourikas, O. Weinmann, A. Schroeter, D. Maerki, L. Sommer, E. Stoeckli, M. E. Schwab

Group Leader: LUKAS SOMMER 9 Regulation of neural stem cell fate by canonical Wnt signalling: K.

Draganova, T. Valenta, S. Falk, K. Basler, L. Sommer Group Leader: ESTHER STOECKLI

10 Slits and Robos in neural crest cell migration and sensory axon

guidance: M. Debrunner, E. T. Stoeckli 11 SHH has multiple functions during spinal cord development: B.

Reichenbach, E. T. Stoeckli 12 Role of Nectin-like molecules in sensory neural circuit formation: J. Frei,

I. Andermatt, E.T. Stoeckli

13 Investigating the role of Glypican in commissural axon guidance using cell type-specific, traceable RNAi: N. H. Wilson, E. T. Stoeckli

14 Nectin-like molecules/SynCAMs are required for post-crossing commissural axon guidance: V. Niederkofler, T. Baeriswyl, R. Ott, E. T. Stoeckli

Group Leader: DIETER ZIMMERMANN 15 A potential role of versican expression and its turnover in axonal

guidance in vivo in a chick model: E. Cassoly, E. T. Stoeckli, D. Zimmermann


Synaptic Transmission and Plasticity 7

SYNAPTIC TRANSMISSION AND PLASTICITY Group Leader: JEAN-MARC FRITSCHY 16 Molecular organization of GABAA receptor subtypes in the spinal cord

dorsal horn: J. Paul, R. Witschi, J.-M. Fritschy, H. U. Zeilhofer, Group Leader: URS GERBER 17 Conditions for activation of postsynaptic metabotropic glutamate

receptors in rat hippocampus: W. Fan, U. Gerber Group Leader: KEVAN MARTIN 18 Dopaminergic innervation of the macaque prefrontal cortex: a tyrosine

hydroxylase immunohistochemical study of Area 10: I. Spühler, R. Bopp K. Martin

Group Leader: OLIVIER RAINETEAU 19 The role of the extracellular matrix in neuronal circuit activity and

plasticity: establishment of a cortical slice culture model: C. Orlando, J. Fawcett, A. Matus, O. Raineteau

Group Leader: HANNS ULRICH ZEILHOFER

20 Characterization of HZ166, a novel GABAA receptor subtype-selective

benzodiazepine site ligand, in mouse pain models: A. Di Lio, Z. Wang, R. V. Edwankar, J. M. Cook, H. U. Zeilhofer

21 Opposite effects of CB1 receptor activation in different mouse pain

models: A. Kato, R. Witschi, B. Lutz, G. Marsicano, H. U. Zeilhofer


Molecular and Cellular Neuroscience 8

MOLECULAR AND CELLULAR NEUROSCIENCE Group Leader: JEAN-MARC FRITSCHY 22 SUMOylation and stability of gephyrin at inhibitory synapses: H. Ghosh,

S. Messner, M. Hottiger, J.-M. Fritschy, S. K. Tyagarajan

23 Differential alteration of adult neurogenesis in mice lacking specific GABAA receptor subtypes: V. Duveau, S. Laustela, F. Gianolini, J.-M. Fritschy

Group Leader: SEBASTIAN JESSBERGER 24 The role of de novo lipid synthesis in adult neurogenesis: M. Knobloch,

S. Braun, C. von Schoultz, Ö. Karalay, S. Jessberger 25 Functional role of Prox1 in adult hippocampal neurogenesis: Ö. Karalay,

S. Jessberger 26 Molecular characterization of adult neural stem cells from mouse hippocampus and subventricular Zone: O. Bracko, F. H. Gage, S. Jessberger 27 Imaging neurogenesis in the adult hippocampus: F. Kleine Borgmann, S. Jessberger 28 Role of small Rho-GTPases in adult hippocampal neurogenesis: K. C. Vadodaria, J. Relvas, U. Suter, C. Brakebusch, S. Jessberger 29 Reprogramming neural stem cells to restore hippocampal connectivity in demyelinating disease: S. Braun

Group Leader: ISABELLE MANSUY

30 Histone PTM mapping in the adult moue brain reveals the extent of the

histone code: R. Tweedie-Cullen, J. Reck, I. Mansuy 31 Protein Phosphatase-1 Regulates the Histone Code for Long-term

Memory : J. Gräff, K. Koshibu, F. Heitz, M. Farinelli, M. Beullens, M. Bollen, I. Mansuy



9 Molecular and Cellular Neuroscience

32 E-proteins as neurogenesis modulators: S. Ramelli, R. Fiorelli, C. Boutin, H. Cremer O. Raineteau Group Leader: LUKAS SOMMER

33 Addressing the role of the H3-K27 demethylase KDM6b in PNS development: D. Schwarz, T. Burgold, G. Testa, L. Sommer

Group Leader: UELI SUTER

34 GDAP1 – also a peroxisomal fission factor?: N. Huber, M. Schrader, A. Niemann, U. Suter

35 Role of SVZ derived precursors in inflammatory and non-inflammatory demyelination: C. Porcheri, H. Pohl , F. Cavasinni, A. Bergamaschi, L. Muzio, G. Martino, U. Suter

Group Leader: MICHAEL WELLER

36 Immunologic Characterization of Glioma Stem Cells: F. Wolpert, G.

Eisele, P. Roth, G. Tabatabai, K. Frei, M. Weller

37 Characterizing the role of the pluripotency marker UTF-1 in malignant gliomas: T. Tekiner, J. Schittenhelm, M. Scholl, K. Frei, P. Droege, M. Weller, G. Tabatabai

Group Leader: BERND WOLLSCHEID

38 The Glioma Cell Surface Signal Transduction Network: T. Bock, A.

Hofmann, D. Bausch-Fluck, K. Frei, B.Wollscheid

39 The cell surface protein atlas: D. Bausch-Fluck, A. Hofmann, T. Bock, F. Cerciello, A. Frei, B. Wollscheid


10 Endocrine Regulation, Neuroimmunology

ENDOCRINE REGULATION, NEUROIMMUNOLOGY Group Leader: BURKHARD BECHER 40 Elucidating the role of neutrophils in autoimmune-driven CNS-

inflammation and blood-brain-barrier function: S. Spath, B. Becher 41 Disecting cytokine networks mediating intracranial tumor control: J.

vom Berg, S. Haller, B. Becher 42 Oligodendropathy does not lead to CNS autoimmunity: G. Locatelli, S.

Woertge, T. Buch, F. Frommer, F. Heppner, I. Bechmann, A. Waisman, B. Becher

Group Leader: ADRIANO FONTANA 43 Anti-CD40-induced sickness behavior syndrome is TNFRI dependent

and correlates with clock gene suppression: C. Taraborrelli, S. Petrzilka, G. Cavadini, I. Tobler, T. Birchler, A. Fontana

Group Leader: KARL FREI 44 Absence of T-cells aggravates epileptogenesis and neurodegeneration

in a mouse model of temporal lobe epilepsy (TLE): M. Zattoni, M. Mura, J.-M. Fritschy, K. Frei

Group Leader: OLIVER ULLRICH 45 Adaptive peripheral immune response increases proliferation of neural

precursor cells in the adult hippocampus: S. Wolf, B. Steiner, A. Wengner, M. Lipp, T. Kammertoens, G. Kempermann


Sensory Systems 11

SENSORY SYSTEMS Group Leader: ELISABETTA CHICCA (ZNZ Associate, Institute of Neuroinformatics) 46 Neuromorphic olfaction using aVLSI chips: E. Chicca, F. Stefanini, D. Fasnacht, E. Neftci, G. Galizia

Group Leader: ARMIN CURT 47 Reliability of contact heat evoked potentials: influence of age and segmental distribution on cortical responses and perception: J. Haefeli, J. Blum, A. Curt Group Leader: FRITJOF HELMCHEN 48 Viral expression of yellow cameleon 3.60 allows optical single-spike detection using two-photon imaging in vivo: H. Lütcke, D. J. Margolis, S. Astori, S. Meyer, W. Göbel, S. Kügler, Y. Yang, R. Sprengel, P. H. Seeburg, F. Helmchen, M. T. Hasan Group Leader: BERNHARD HESS 49 Optimal estimation of head angular velocity from vestibular information: experimental and theoretical evidences: J. Laurens, D. Straumann, B. Hess

Group Leader: BJÖRN KAMPA

50 Insights on cortical organization of the rodent visual system: M. Roth, F. Helmchen, B. Kampa Group Leader: SHIH-CHII LIU 51 Periodicity detection using spike timing from the AER EAR: T. Yu, J. Harris, M. Slaney, S. Liu 52 Steering autonomous robots with optic flow: R. Möckel, Shih-Chii Liu


12 Sensory Systems

Group Leader: KEVAN MARTIN

53 A systematic random sampling scheme optimized to detect the proportion of rare synapses in the neuropil: N. M. da Costa, K. Hepp, K. Martin

54 Principles of organization of the circuits of primate neocortex: J.

Anderson, H. Kennedy, K. Martin

Group Leader: SILVESTRO MICERA

55 Neuronal responses to electrical stimulation of the vestibular system: C. Fischer, J. DiGiovanna, M. Morari, D. Merfeld, S. Micera

Group Leader: STEPHAN NEUHAUSS 56 Expression of myosinVIIa paralogs in zebrafish: C. Hodel, M. Heidemann, M. Gesemann, O. Biehlmaier, S. Neuhauss

57 Impaired energy metabolism leads to reduced vision in the zebrafish noir mutant: C. Maurer , H. Schönthaler , S. Neuhauss

58 Simple behavioral assay for testing vision of adult zebrafish and medaka: K. Müller, S. Neuhauss

59 Metabotropic glutamate receptors in the zebrafish retina: M. Haug, Y.

Huang, M. Gesemann, S. Neuhauss

60 Arrestin availability in cone photoreceptors modulates opsin inactivation: S. Renninger, M. Gesemann, S. Neuhauss

Group Leader: ROLF PFEIFER

61 Mastering the Man-Machine communication: Sensory feedback for the perceptual embodiment of a neuroprosthesis: M. Seps, J. Vargas, A. Hernandez Arieta


62 Heterogeneity of glutamatergic neurons in the adult mouse olfactory bulb: E. Winpenny, M. Brill, M. Götz, O. Raineteau


Sensory Systems 13

Group Leader: ROBERT RIENER 63 Heart rate response via posture and motion in vegetative state patients: a feasibility study: M. Wieser, L. Bütler, J. Haefeli, R. Riener

Group Leader: MARKUS RUDIN 64 Hyperalgesic effects of low dose lidocaine detected by BOLD fMRI in mice: S. Bosshard, C. Baltes, H. Zeilhofer, M. Rudin

Group Leader: DOMINIK STRAUMANN

65 Direction dependent contribution of inertial information to direction discrimination during passive translation in humans: I. Olasagasti, D. Straumann


14 Motor Systems

MOTOR SYSTEMS Group Leader: GREGOIRE COURTINE 66 Combinatory stimulation of monoaminergic receptors transforms spinal

circuits from non-functional into highly functional states after complete loss of supraspinal input: O. Maerzendorfer, P. Musienko, R. van den Brand, J. Heutschi, L. Friedli, G. Courtine

67 Multisite spinal cord stimulation strategies to promote locomotion in

paralyzed spinal rats: J. DiGiovanna, P. Musienko. O. Maerzendorfer, M. Morari, S. Micera, G. Courtine

68 Specific functions of monoaminergic receptors in the control of spinal

locomotion: P. Musienko, O. Maerzendorfer, R. van den Brand, J. Heutschi, L. Friedli, G. Courtine

69 Combinatory neurorehabilitation interventions promote the recovery of

overground locomotion following a severe spinal cord injury (SCI) in adult rats: L. Friedli, R. van den Brand, J. Heutschi, P. Musienko, O. Maerzendorfer, G. Courtine

70 A new rodent model of severe but partial spinal cord injury leading to progressive deterioration of function as observed in human patients: J. Heutschi, R. van den Brand , L. Friedli, P. Musienko, O. Maerzendorfer, G. Courtine

Group Leader: VOLKER DIETZ 71 Preparation and performance of obstacle steps: interaction between brain and spinal neuronal activity: J. Michel, S. Vögeli, V. Dietz

72 Spinal reflexes: a possible marker for walking ability in incomplete spinal cord injury: M. Hubli, V. Dietz, M. Bolliger

Group Leader: KYNAN ENG

73 Neural correlates of observation, imagination and imitation of goal-

oriented leg movements: an fMRI study: M. Villiger, N. Estevez, S. Hotz-Boendermaker, M.-C. Hepp-Reymond, S. Kollias, D. Kiper, K Eng


Motor Systems 15

Group Leader: ROGER GASSERT

74 fMRI-HandCARE, a robotic tool to track therapy-induced neuroplas-ticity: J. Duenas, M. Hara, O. Lambercy, D. Chapuis, R. Gassert

75 The role of proprioception in learning a novel motor task: R. Benthem de

Grave, A. Melendez, E. Burdet, O. Lambercy, R. Gassert

76 The ReHapticKnob: a novel robot for assessment and rehabilitation of hand function: O. Lambercy, D. Chapuis, R. Gassert

Group Leader: HUUB VAN HEDEL 77 Reaction time of the foot in people with incomplete spinal cord injury –

a feasibility study: R. Labruyère, H. van Hedel 78 Pain and depression hardly affect daily life activities within the first year

after spinal cord injury: P. Dokladal, S. Hotz-Boendermaker, H. van Hedel 79 Conversion in ASIA impairment scale during the first year after

traumatic spinal cord injury: M. Spiess, R. Müller, R. Rupp, C. Schuld, H. van Hedel

Group Leader: SPYROS KOLLIAS 80 Can a robot-hand take the place of a missing hand? A project with

upper limb amputees: N. Estévez, A. Sposito, M. Villiger, V. Bugmann, M.-C. Hepp-Reymond, R. Gassert, P. Brugger, S. Hotz, A. Maravita, S. Kollias, A. Hernandez Arieta

81 Preliminary fMRI results of the MR-compatible arm-robot using a block and an event-related design: N. Estévez, N. Yu, C. Hollnagel, M.l Villiger, M.-C. Hepp-Reymond, R. Gassert, M. Meyer, R. Riener , S. Kollias

Group Leader: ANDREAS MEYER-HEIM 82 Constraint induced movement therapy (CIMT) for children with obstetric

brachial plexus palsy – two single case series.: F. Eugster Buesch, B. Schlaepfer, E.D. de Bruin, G. Wohlrab, C. Ammann-Reiffer, A. Meyer-Heim.


16 Motor Systems

83 Comparison of different video gait analysis rating scales to analyse improvement in gait function after locomotion therapy: S. Hänseler, R. Müller, A. Meyer-Heim

Group Leader: ROBERT RIENER 84 Walking within a scanner: A new approach of simulating walking in an

fMRI environment: C. Hollnagel, M. Brügger, N. Estevez, Ningbo Yu, V. Dietz, S. Kollias, R. Riener

85 Functional recovery with task-specific robot-aided arm therapy: a

multicenter clinical trial in stroke: V. Klamroth, A. Kollmar, M. Guidali, M. Sattelmayer, A. Curt, T. Ettlin, J. Blanco, A. Luft, R. Riener

Group Leader: HANSJÖRG SCHERBERGER 86 Ensemble methods to boost the decoding performance of a hand

grasping BMI: E. Subasi, B. R. Townsend, H. Scherberger Group Leader: MARTIN SCHWAB 87 New circuits form in the CNS after spinal cord injury: A. Ghosh, B.

Zörner, L. Filli, E. Sydekum, B. Weber, M. Rudin, M. E. Schwab

Group Leader: DOMINIK STRAUMANN 88 Eye position dependency of nystagmus during a caloric-step stimulus:

C. Bockisch, M. Susac, D. Straumann, S. Hegemann


Sleep and Sleep Disorders 17

SLEEP AND SLEEP DISORDERS Group Leader: PETER ACHERMANN 89 Source localization of slow oscillations in nonREM sleep: effect of sleep

deprivation: A. Bersagliere, P. Achermann

90 Effects of Pulse-Modulated Radio Frequency Electromagnetic Fields (RF-EMF) on the Human Brain: Critical Field Parameters: M. Schmid, A. Bratic, S. Regel, A. Bersagliere, T. Rusterholz, S. Loughran, M. Murbach, N. Kuster, P. Achermann

91 Assessment of sleep-wake behavior in persistent vegetative and

minimally conscious states: S. Loughran, S. Regel, L. Buetler, M. Wieser, R. Riener, P. Achermann

Group Leader: RETO HUBER 92 Local increase of sleep SWA in prepubertal children and adolescents

after visuomotor learning: M. Ringli, S. Kurth, A. Geiger, O. Jenni, R. Huber

93 Relationship between sleep slow waves and local grey matter volumes

during development: A. Buchmann, M. Ringli, S. Kurth, O. Jenni, R. Huber

Group Leader: HANS-PETER LANDOLT 94 Genetic variation in adenosine deaminase, attention and sleep in

humans: V. Bachmann, F. Klaus, P. Brugger, S. Bodenmann, N. Schäfer, W. Berger, H.-P. Landolt

Group Leader: JOHANNES SARNTHEIN 95 State space mapping of sleep and wakefulness in healthy controls and

Parkinson patients: J. Sarnthein, E. Werth, U. Kallweit, C. Bassetti, C. Baumann

Group Leader: IRENE TOBLER


18 Sleep and Sleep Disorders

96 Adenosine kinase and its role in sleep in mice: S. Palchykova, A. Gerling, R. Winsky-Sommerer, I. Tobler


Neural Basis of Behavior 19

NEURAL BASIS OF BEHAVIOR Group Leader: JORAM FELDON 97 Prenatal immune activation induces primary defects in structural and

functional dopaminergic development relevant to schizophrenia: S. Vuillermot, J. Feldon, U. Meyer

98 Maternal immune activation with a synthetic analogue of double

stranded RNA affects cognitive function and expression of AKT1 in adult mice: B. Bitanihirwe, J. Feldon, U. Meyer

Group Leader: DIETRICH LEHMANN

99 Hypnotizability and EEG power spectra before hypnosis: C. Andreou, D.

Lehmann, P. Jönsson, P.L. Faber, D.B. Terhune and E. Cardena Group Leader: HANS-PETER LIPP 100 The entorhinal cortex of the Megachiroptera: A comparative study of

two species of African fruit bats: C. Gatome, I. Amrein, D. Mwangi, L. Slomianka, H.-P. Lipp

101 Minor behavioral phenotype of SNAP-25 heterozygeous mice: I.

Corradini, M. Matteoli, H.-P. Lipp, H. Welzl, D. Wolfer Group Leader: BRUNO WEBER 102 Neuronal response of the awake, behaving rat during decision making:

J. Mayrhofer, F. Haiss, D. Margolis, M. Hasan, F. Helmchen, B. Weber

Group Leader: DAVID WOLFER (ZNZ associate, Institute of Anatomy) 103 From mazes to IntelliCage: Novel approach to evaluation of mouse

cognition: V. Voikar, G. Colacicco, E. Vannoni, D. Wolfer


20 Cognitive Neuroscience and Neuropsychology

COGNITIVE NEUROSCIENCE AND NEUROPSYCHOLOGY Group Leader: DANIEL BRANDEIS 104 Individual differences in the frontal midline theta working memory

effect: modulation by accuracy and individually determined peaks: U. Maurer, S. Brem, M. Liechti, R. Lüchinger, K. Bucher, L. Michels, D. Brandeis

105 Preliminary tomographic neurofeedback results from children with

ADHD: M. Liechti, S. Maurizio, H. Heinrich, G. Thalmann, L. Meier, Y. Schwitter, M. Hartmann, S. Walitza, H.-C. Steinhausen, L. Jäncke, R. Drechsler, D. Brandeis

106 Frequency dependent EEG power synchronization correlates with the

BOLD signal during working memory: R. Lüchinger, L. Michels, K. Bucher, K. Jann, S. Bach, E. Martin, D. Jeanmonod, D. Brandeis

107 Good phonological awareness and left hemispheric specialisation: a

key for good reading?: S. Bach, S. Brem, U. Richardson, J. Buckelmüller, D. Brandeis

Group Leader: KATHARINA HENKE 108 Hippocampus engages in the unconscious associative encoding and

retrieval of new conceptual associations: P. Colella, S. Ruch, T. Reber, P. Vuilleumier, M. Hauf, K. Henke

109 Declarative Memory Consolidation during a Daytime Nap: O. Markes, S.

Duss, T. Reber, S. Ruch, D. Oppliger, J. Mathis, Corinne Roth, K. Henke 110 Generalizations over temporally distinct ‚non-conscious episodes’

engage the hippocampus during learning and retrieval.: T. Reber, P. Colella, D. Oppliger, P. Boesiger, R. Luechinger, K. Henke

Group Leader: ALUMIT ISHAI 111 The gender of face stimuli is represented in multiple regions in the

human brain: C. Kaul, G. Rees, A. Ishai 112 Expertise reduces neural cost but does not modulate repetition

suppression: M. Wiesmann, A. Ishai


Cognitive Neuroscience and Neuropsychology 21

Group Leader: LUTZ JÄNCKE 113 Standing on a clockface: a mind’s eye exploration of backspace : C.

Tamagni, T. Loetscher, P. Brugger 114 Altered structural brain network topology in grapheme-colour

synaesthesia: J. Hänggi, D. Wotruba, L. Jäncke 115 The architecture of the chess player’s brain: J. Hänggi, K. Brütsch, A.

Siegel, L. Jäncke 116 Neurophysiological evidence towards impaired musical sound

perception in cochlear-implant users: P. Sandmann, A. Kegel, T. Eichele, N. Dillier , W. Lai, S. Debener, L. Jäncke, Martin Meyer

117 Neural correlates of general fluid intelligence: N. Langer, J.Hänggi, L.

Gianotti, L.Jäncke

Group Leader: HENNRIC JOKEIT

118 Verbal semantic processing after language dominant anterior temporal

lobe resection versus transsylvian selective amygdalo-hippocampectomy: R. Burckhardt, S. Broicher, A. Ebner, H. Pannek, Y. Yonekawa, T. Grunwald, G. Krämer, M. Kurthen, H. Jokeit

Group Leader: ERNST MARTIN

119 ”Rette Calcularis” - a mental number line training for children with

developmental dyscalculia: U. Grond, K. Kucian, S. Rotzer, C. Schönmann, B. Henzi, E. Martin, M. von Aster

120 Neuroplastic changes after 5-weeks of number line training in children:

K. Kucian, B. Henzi, C. Schönmann, S. Rotzer, M. von Aster, E. Martin Group Leader: MARTIN MEYER

121 Direct current-induced short-term modulation of the left dorsolateral

prefrontal cortex while learning auditory presented nouns: S. Elmer, M. Burkard, B. Renz, M. Meyer, L. Jancke

122 ERP differences of prelexical processing between dyslexic and non-

dyslexic children: M. Kast, Stefan Elmer, L. Jancke, M. Meyer


22 Cognitive Neuroscience and Neuropsychology

Group Leader: BENJAMIN YEE

123 Molecular down-regulation of adenosine kinase in forebrain leads to a severe deficit on pavlovian fear conditioning and impairs spatial familiarity judgment in the Y-maze: S. McGarrity, P. Singer, D. Boison, J. Feldon, B. Yee


Aging and Disorders of the Nervous System 23

AGING AND DISORDERS OF THE NERVOUS SYSTEM Group Leader: STEVEN FRY 124 Behavioral read-out system applied for biomedical and neurobiological

research in Drosophila melanogaster: J. Balmer, S.Fry

Group Leader: URS GERBER 125 Neuron-astrocyte interactions during epileptiform activity in the rat

hippocampus in vitro: G. Coiret, U. Gerber, F. Tiaho, F. & P. Benquet Group Leader: LUTZ JÄNCKE 126 Reduced white-matter integrity in social anxiety disorder - a DTI

examination of the uncinate fasciculus: V. Baur, J. Hänggi, L. Jäncke, M. Rufer, U. Herwig, A. Brühl

127 Increased brain activations during the processing of phobia-unspecific emotional pictures in social anxiety disorder: V. Baur, M. Rufer, A. Delsignore, T. Kaffenberger, L. Jäncke, U. Herwig, A. Brühl

Group Leader: IRENE KNÜSEL

128 Aging affects the survival of GABAergic projection neurons in the basal forebrain: A. Madhusudan, C. Sidler, I. Knuesel 129 Reduced Reelin expression accelerates amyloid-β plaque formation in- vivo: S. Kocherhans, A. Madhusudan, J. Doehner, K. Breu, R. Nitsch, J.- M. Fritschy, I. Knuesel 130 Reelin-positive plaques co-localize with murine amyloid-ß in the hippocampus of aged wild-type mice: J. Doehner, A. Madhusudan, U. Konietzko, J.-M. Fritschy, I. Knuesel

Group Leader: UWE KONIETZKO

131 Analysis of Aß-mediated disruption of synaptic plasticity in transgenic arcAß mice: A. Trutzel, M. Knobloch, R. Nitsch, U. Konietzko


24 Aging and Disorders of the Nervous System

132 Nuclear signaling by the APP intracellular domain (AICD) occurs predominantly through the amyloidogenic processing pathway: Z. Goodger, L. Rajendran, A. Trutzel, B. Kohli, R. Nitsch, U. Konietzko

Group Leader: MICHAEL LINNEBANK

133 On the interaction of homocysteine metabolism and Alzheimer’s disease: in vitro and in vivo experiments: M. Farkas, S. Keskitalo, L. Kulic, M. Weller, M. Linnebank

Group Leader: ROGER NITSCH 134 M1 acetylcholine receptor modulation has acute effects on hippocampal

levels of abeta in awake and freely moving mice: T. Welt, L. Kulic, S. Cattepoel, R. Nitsch

135 Aβ immunotherapy protects morphology and survival of adult-born neurons in doubly transgenic APP/PS1 mice: B. Biscaro, O. Lindvall, C. Hock, C. Ekdahl, R. Nitsch

136 Chronic intranasal treatment with an Anti-Aβ42 scFv antibody

ameliorates amyloid pathology in a transgenic mouse model of Alzheimer’s disease: S. Cattepoel, M. Hanenberg, L. Kulic, R. Nitsch

137 A DARPin library screening reveals interaction partners with amyloid-beta: M. Hanenberg, M. Maier, P. Parizek, A. Plückthun, R. Nitsch

138 Cerebrovascular & brain metabolic abnormalities in the arcabeta mouse

model of Alzheimer’s disease: M. Merlini, E. Meyer, A. Ulmann-Schuler, B. Weber, M. Wyss, Roger M. Nitsch

139 Anti-Aβ memory in Alzheimer`s disease: intermediate study results: A.

Szodorai, C. Marty, C. Hock, R. Nitsch 140 Neurotoxicity of recombinant Abeta: I. Vodopivec. V. Finder, O

Ovichinnikova, R. Nitsch, R. Glockshuber Group Leader: ROBERT RIENER 141 Cognimat: a virtual reality system for cognitive training of patients with dementia: B. Buss, R. Nitsch, C. Hock, P. Pyk, O. Ballach, D. Kiper, R. Riener


Aging and Disorders of the Nervous System 25

Group Leader: JOHANNES SARNTHEIN 142 Increased variability of the pattern VEP due to daily iron fortification: M.

Andersson, M. Zimmermann, D. Zumsteg, J. Sarnthein Group Leader: BRIGITTE SCHURCH 143 Botulinum toxin A treatment in overactive bladder symptoms of

multiple sclerosis patients: can 100 units be effective and still preserve voiding function?: U. Mehnert, J. Birzele, K. Reuter, B. Schurch

144 The effect of tolterodine 4 and 8 mg on the heart rate variability in

healthy subjects: M. Schiffers, P. Sauermann, B. Schurch, U. Mehnert

Group Leader: HANS STASSEN

145 Twins discordant and concordant for schizophrenia: inferences from

psychopathology, brain wave patterns and inflammatory response system: S. Braun, K. Lötscher, M. Weisbrod, H. Stassen

146 The difficulties of reproducing conventionally derived molecular-genetic results through 500k-Chip technology: H. Stassen, K. Hoffmann, Ch. Scharfetter

147 Polypharmacy in psychiatry: clinical practice versus empirical evidence: K. Lötscher, S. Braun, R. Bridler, H. Stassen

Group Leader: UELI SUTER 148 A novel mouse model for demyelination: H. Pohl, T. Mueggler, C.

Porcheri, M. Kulstrunk, L. Bachmann, D. Riethmacher, M. Rudin,.U. Suter Group Leader: KATHRIN ZAUGG (ZNZ associate, Radiooncology Clinic)

149 CPT1C: a putative regulator of tumor growth and metabolism: I. Lohse,

J. Feng, N. Macedo-Sanchez, T. W. Mak, K. Zaugg


26 Computation and Modeling

COMPUTATION AND MODELING Group Leader: RODNEY DOUGLAS 150 Motor control using factor graphs: D. Goehlsdorf, M. Cook 151 Cortical processing on distributed networks of silicon spiking neurons:

E. Neftci, E. Chicca, G. Indiveri, R. Douglas 152 Simulating the development of selforganizing winner-take-all networks: R. Bauer, F. Zubler, R. Douglas Group Leader: GIACOMO INDIVERI 153 Modeling selective attention using event-based neuromorphic VLSI architectures: D. Sonnleithner, G. Indiveri 154 A conductance-based silicon neuron circuit: P. Livi, G. Indiveri 155 Circuits, systems and algorithms for event-driven computation: S. Moradi, D. Fasnacht, G. Indiveri 156 Software tools for real-time neural network emulations using neuromorphic VLSI technology: S. Sheik, E. Neftci, D. Sonnleithner, F. Stefanini, G. Indiveri 157 Cognitive acoustic scene analysis: S. Sheik, E. Chicca, G. Indiveri 158 Sound Recognition using event-based neuromorphic VLSI architectures: M. Abdollahi, F. Stefanini, S.-C. Liu, H. Hermanski, G. Indiveri

Group Leader: SHIH-CHII LIU 159 Synergies between adaptation and synaptic plasticity in a model of auditory map formation: P. D’Souza, R. Hahnloser, S.-C. Liu

160 Input evoked nonlinearities in silicon dendritic circuits: Y. Wang, S.-C.

Liu

Group Leader: RUEDI STOOP


Computation and Modeling 27

161 Stochastic resonant behavior of van der Pol oscillators coupled by

time-varying resistor: Y. Uwate, Y. Nishio, R. Stoop 162 Cochlear Hopf-nonlinearities and pitch perception: S. Martignoli, R.

Stoop

163 Animal courtship from a language point of view: R. Stoop, T. Jasa, P. Nüesch, M. Schüle,

Group Leader: BRUNO WEBER 164 Modeling the effects of local cerebro-vascular changes: J. Reichold, M.

Stampanoni, A. L. Keller, P. Jenny, B. Weber

165 Benchmark testing objective functions in a flux balance analysis model of neuron-astrocyte metabolic interactions: R. Jolivet, A.K. Singh, P.J. Magistretti, B. Weber

Group Leader: MARTIN WOLF 166 Estimation and characterisation of physiological oscillations measured

with functional near-infrared spectroscopy by using empirical mode decomposition: F. Scholkmann, I. Trajkovic, M. Wolf

http://de.wikipedia.org/wiki/L%C3%BCge

http://de.wikipedia.org/wiki/L%C3%BCge


28 Biomedical Technology and Imaging

BIOMEDICAL TECHNOLOGY AND IMAGING Group Leader: GREGOIRE COURTINE 167 A multi-directional robotic support system for neurorehabilitation of rodents with motor disabilities: U. Keller, H. Vallery, A. Brunschweiler, R. Riener, G. Courtine

168 Neuroprosthetic spinal cord electrode arrays to restore mobility in paralyzed spinal rats: A. Larmagnac, P. Musienko. J. Vörös, G Courtine Group Leader: KYNAN ENG 169 The SpiderGlove: Low-cost, highly-adjustable, modular measurement of

human grasping: P. Pyk, L. Holper, D. Mochnacki, D. Kiper, K. Eng Group Leader: HUUB VAN HEDEL 170 Improved assessment of grasp in patients with spinal cord injury – what

clinical scores do not tell us: N. Oess, J. Wanek, U. Albisser, C. Rudhe, H. van Hedel

171 Before you can grab it, you have to reach for it! Instrumented assessment of reaching in patients with tetraplegia: J. Wanek, N. Oess, U. Albisser, C. Rudhe, H. van Hedel

Group Leader: FRITJOF HELMCHEN 172 A novel approach to probe pain-processing neuronal networks in the mouse spinal cord by 2-photon calcium imaging in vivo: H. Johannssen, F. Helmchen

173 High-speed two-photon calcium imaging of neuronal network dynamics in vivo using acousto-optic scanners: B. Grewe, D. Langer, H. Kasper, B. Kampa, F. Helmchen

Group Leader: ANDREAS MEYER-HEIM 174 Virtual Realities as a Motivation Tool for the Gait Training in the Pediatric Lokomat: T. Schuler, R. Müller, K. Brütsch, A. Meyer-Heim


Biomedical Technology and Imaging 29

175 Virtual reality enhances walking performance in robotic assisted gait training of children: K. Brütsch, S. Schaumann, A. Duschau-Wicke A. König, L. Zimmerli, L. Lünenburger, S. Mérillat (-Koeneke), R. Riener, L. Jäncke, A. Meyer-Heim

Group Leader: SILVESTRO MICERA

176 Multi-channel Textile Neuroprosthesis for Grasping: M. Lawrence, A. Crema, N. Gruber, S. Mangold, S. Micera, M. Morari

177 Smart Armeo: A system for advanced stroke rehabilitation: M. Lawrence, A. Crema, P. Schenk, S. Micera, G. Colombo, M. Morari

178 FES Ankle Control for the Lokomat: R. Nguyen, S. Perala, S. Micera, M. Morari

Group Leader: MARKUS RUDIN

179 Near Infrared Fluoresence (NIRF) Imaging in a mouse model of Alzheimer’s Disease.: F. Kranz, B. Koelsch, T. Mueggler, K.-H. Altmann, R. Nitsch, M. Rudin

180 Characterization of the 5HT1A receptor system in mice using pharmacological fMRI: F. Razoux, T. Mueggler, A. Buehler, H. Russig, C. Baltes, I. Mansuy, M. Rudin 181 A dual-modality FMT/MRI system for simultaneous murine brain measurements: K. Dikaiou, F. Stuker, C. Baltes, J. Ripoll, L. Carrara, E. Charbon, M. Rudin

Group Leader: BRUNO WEBER

182 Does the brain use lactate as an energy substrate? – A radiotracer approach: M. T. Wyss, N. Obrist, P.-J. Magistretti, A. Buck, B. Weber

183 Blockade of the metabotropic glutamate receptor mGluR5 does not affect neurovascular coupling in adult Sprague-Dawley rats: N. Calcinaghi, R. Jolivet, M. Wyss, C. Zunzunegui, F. Gasparini, A. Buck, B. Weber

Group Leader: MARTIN WOLF


30 Biomedical Technology and Imaging

184 Detection of neuronal activity by near infrared imaging and EEG: M.

Biallas, F. Scholkmann, C. Von der Grün, AS. Micholt, R. Lüchinger, V. Marcar, D. Haensse, M. Wolf


31

ZNZ GROUP LEADERS (in alphabetic order and with poster numbers) Achermann P., Institute of Pharmacology and Toxicology, UZH 89-91

Becher B., Department of Neurology, USZ 40-42 Brandeis D., Dept. of Child and Adolescent Psychiatry, UZH 104-107

Chicca E., Institute of Neuroinformatics, UZH/ETHZ 46 Courtine G., Experimental Neurohabilitation Laboratory, UZH 66-70, 167-168 Curt A., Department of Neurology, USZ 47

Dietz V., Spinal Cord Injury Center, Balgrist University Hospital 71-72

Eng K., Institute of Neuroinformatics, UZH/ETHZ 73, 169

Feldon J., Laboratory of Behavioral Biology, ETHZ 97-98 Fontana A., Department of Clinical Immunology, USZ 43 Frei K., Department of Neurosurgery, USZ 44 Fritschy J.-M., Institute of Pharmacology and Toxicology, UZH 1, 16, 22-23, Fry S., Institute of Neuroinformatics, UZH/ETHZ 124 Gassert R., Rehabilitation Engineering Lab, ETHZ 74-76 Gerber U., Brain Research Institute, UZH 17, 125

Helmchen F., Brain Research Institute, UZH 48, 172-173 Hengartner M., Institute of Molecular Biology, UZH 2-3 Henke Westerholt K., Department of Psychology, Uni BE 108-110 Hess B., Department of Neurology, USZ 49 Huber R., Children’s University Hospital Zurich 92-93

Indiveri G., Institute of Neuroinformatics, UZH/ETHZ 153-158 Ishai A., Institute of Neuroradiology, USZ 111-112

Jäncke L., Institute of Psychology, UZH 113-117, 126-127 Jessberger S., Institute of Cell Biology, ETHZ 24-29 Jokeit H., Department of Neuropsychology, Swiss Epilepsy Center 118

Kampa B., Brain Research Institute, UZH/ETHZ 50 Knüsel I., Institute of Pharacology, UZH 128-130 Kollias S., Institute for Neuroradiology, USZ 80-81 Konietzko U., Division of Psychiatry Research, UZH 131-132

Landolt H.-P., Institute of Pharmacology and Toxicology, UZH 94 Lehmann D., KEY Institute for Brain-Mind Research, PUK/UZH 99 Linnebank M., Department of Neurology, USZ 133 Lipp H.-P., Institute of Anatomy, UZH 4, 100-101 Liu S.-C., Institute of Neuroinformatics, UZH/ETHZ 51-52, 159-160


32

Mansuy I., Brain Research Institute, UZH 30-31 Martin E., Children’s University Hospital Zurich 119-120 Martin K., Institute of Neuroinformatics, UZH/ETHZ 18, 53-54 Meyer M., Institute of Psychology, UZH 121-122 Meyer-Heim A., Children’s Hospital, USZ 82-83, 174-175 Micera S., Spinal Cord Injury Center, Balgrist 55, 176-178

Neuhauss S., Brain Research Institute, UZH 56-60 Nitsch R., Division of Psychiatry Research, UZH 134-140

Pfeifer, R., Institute of Neuroinformatics, UZH/ETHZ 61,

Raineteau O., Brain Research Institute UZH/ETHZ 5-6, 19, 32, 62 Riener R., Sensory-Motor Systems Lab, ETHZ 63, 84-85,141 Rudin M., Institute for Biomedical Eng. and Dept. of Materials 64, 179-181

Sarnthein J., Department of Neurosurgery, USZ 95, 142 Scherberger H., Institute of Neuroinformatics UZH/ETHZ 86 Schürch B., Spinal Cord Injury Center, USZ 143-144 Schwab M.E., Brain Research Institute UZH/ETHZ 7-8, 87 Sommer L., Institute of Cell Biology, ETHZ 9, 33, Stassen H.H., Psychiatric University Hospital Zurich 145-147 Stoeckli E., Institute of Zoology, UZH 10-14 Stoop R., Institute of Neuroinformatics, UZH/ETHZ 161-163 Straumann D., Department of Neurology, USZ 65, 88 Suter U., Institute of Cell Biology, ETHZ 34-35, 148

Tobler I., Institute of Pharmacology and Toxicology, UZH 96

Ullrich O., Institute of Anatomy, UZH 45

Van Hedel H., Spinal Cord Injury Center 77-79, 170-171

Weber B., Department of Nuclear Medicine, USZ 102, 164-166, 182-183 Weller M., Department of Neurology, USZ 36-37 Wolf M., Department of Neonatology, USZ 166, 184 Wolfer D., Institute of Anatomy, UZH 103 Wollscheid B., Institute of Molecular Systems Biology, ETHZ 38-39 Yee B., Laboratory of Behavioural Neurobiology 123 Zaugg K., Institute of Neuroradiology, USZ 149 Zeilhofer H.-U., Institute of Pharmacology and Toxicology, UZH 20-21 Zimmermann D., Department of Pathology, USZ 15

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ZNZ SYMPOSIUM 2009 - UZH