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WuXi Pharma Tech Jiawei Chen Nov 4th 2009 WuXi Pharma Tech NYSE: WX

WuXi Pharma Tech - University of Virginia...facility with total 300,000 square feet. Advantage in China Abundant resources and fewer regulatory constraints on animal testing. Multiple

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Page 1: WuXi Pharma Tech - University of Virginia...facility with total 300,000 square feet. Advantage in China Abundant resources and fewer regulatory constraints on animal testing. Multiple

WuXi Pharma Tech

Jiawei Chen

Nov 4th 2009

WuXi Pharma TechNYSE: WX

Page 2: WuXi Pharma Tech - University of Virginia...facility with total 300,000 square feet. Advantage in China Abundant resources and fewer regulatory constraints on animal testing. Multiple

Agenda

� I. CRO industry overview

� II. Company overview

� III. Thesis points

� IV. Risk

� V. VAR Summary

� VI. Valuation

Page 3: WuXi Pharma Tech - University of Virginia...facility with total 300,000 square feet. Advantage in China Abundant resources and fewer regulatory constraints on animal testing. Multiple

I. Industry Overview: CRO

� Contract Research Organization (CRO) is a

service organization that provides support to the

pharmaceutical/biotech industry

� Reasons for outsourcing to CROs� Reasons for outsourcing to CROs

� Drug companies can convert fixed costs into variable

costs

� Increased complexity of clinical trials

� Knowledge of regulatory affairs in a particular country

of interest

Page 4: WuXi Pharma Tech - University of Virginia...facility with total 300,000 square feet. Advantage in China Abundant resources and fewer regulatory constraints on animal testing. Multiple

Market� Valued at US$18bn in 2008

�Approximately 500 CROs globally

Global CRO Trend

�Grow at a CAGR of 14% to reach US$24bn in 2010

� Demand for CRO: increase by 17% annually

the next 3 to 5 years

� R&D outsourcing share as % of total global expenditure:

double to 10% in 2013E (from 5% in 2008)

Page 5: WuXi Pharma Tech - University of Virginia...facility with total 300,000 square feet. Advantage in China Abundant resources and fewer regulatory constraints on animal testing. Multiple

Chinese CRO Market

• Expect the sector to expand at an 18% CAGR

till 2011

• Foreign-based CROs started operating in

China in the 1990s, focusing on pre-clinical

laboratory functions.

Page 6: WuXi Pharma Tech - University of Virginia...facility with total 300,000 square feet. Advantage in China Abundant resources and fewer regulatory constraints on animal testing. Multiple

II. Company overview

� The largest CRO in China with total revenue of US$253.5mn in 2008.

� Established in 2000, WuXi AppTec is a leading global CRO with operations in China and the United States. with operations in China and the United States.

� Provide integrated portfolio across the discovery-to-commercialization spectrum.

� A highly educated workforce

employees: 3,700

scientists: 2,900 (the majority with advanced degrees)

Page 7: WuXi Pharma Tech - University of Virginia...facility with total 300,000 square feet. Advantage in China Abundant resources and fewer regulatory constraints on animal testing. Multiple

Company Structure

Page 8: WuXi Pharma Tech - University of Virginia...facility with total 300,000 square feet. Advantage in China Abundant resources and fewer regulatory constraints on animal testing. Multiple

III. Thesis Points

1. Solid fundamental: High-Quality

Laboratory Services business

2. New promising business: Toxicology2. New promising business: Toxicology

3. Talented pool with cost advantage

Page 9: WuXi Pharma Tech - University of Virginia...facility with total 300,000 square feet. Advantage in China Abundant resources and fewer regulatory constraints on animal testing. Multiple

1. Laboratory Services…

Page 10: WuXi Pharma Tech - University of Virginia...facility with total 300,000 square feet. Advantage in China Abundant resources and fewer regulatory constraints on animal testing. Multiple

Remain the growth engine

� laboratory services revenue to grow at a 16% CAGR from 2009E- 2011E

� 100% customer retention rate

� provide fully integrated “one-stop shopping” service

Page 11: WuXi Pharma Tech - University of Virginia...facility with total 300,000 square feet. Advantage in China Abundant resources and fewer regulatory constraints on animal testing. Multiple

Revenue breakdown 2007-

2011E

Page 12: WuXi Pharma Tech - University of Virginia...facility with total 300,000 square feet. Advantage in China Abundant resources and fewer regulatory constraints on animal testing. Multiple

High level of service

satisfaction

2006 2007 2008

Top 10 customer

concentration69% 74% 54%

Retention of

top 10

customers

100% 100% 100%

Average revenues

per top 10

customer (US$ mn)

4 .8 10.0 13.8

Page 13: WuXi Pharma Tech - University of Virginia...facility with total 300,000 square feet. Advantage in China Abundant resources and fewer regulatory constraints on animal testing. Multiple

Integrated Services for

Pharmaceuticals

These integrated end-to-end capabilities

allow customers to realize more R&D

potential in a cost effective and rapid

manner

Page 14: WuXi Pharma Tech - University of Virginia...facility with total 300,000 square feet. Advantage in China Abundant resources and fewer regulatory constraints on animal testing. Multiple

intensive requirements of developing new

Integrated Services for

Biologics

� intensive requirements of developing new

drugs

�A single-source provider allows for seamless

transition and increase efficiency

Page 15: WuXi Pharma Tech - University of Virginia...facility with total 300,000 square feet. Advantage in China Abundant resources and fewer regulatory constraints on animal testing. Multiple

2. Promising Toxicology

What is toxicology??

� Studies that typically involve testing on animals and

which are designed to rule out serious side-effects of a which are designed to rule out serious side-effects of a

drug

� Typically have high entry barriers in term of technology

and capital investment

Page 16: WuXi Pharma Tech - University of Virginia...facility with total 300,000 square feet. Advantage in China Abundant resources and fewer regulatory constraints on animal testing. Multiple

Wuxi’s advantage

� Suzhou facility will mark Asia's largest toxicology facility with total 300,000 square feet.

� Advantage in China

Abundant resources and fewer regulatoryAbundant resources and fewer regulatoryconstraints on animal testing.

� Multiple pharmaceutical clients visited the facility and were impressed by the layout.

Page 17: WuXi Pharma Tech - University of Virginia...facility with total 300,000 square feet. Advantage in China Abundant resources and fewer regulatory constraints on animal testing. Multiple

Key determinant of long-term return

trends

80

100

120 Strong revenue

growth will

ultimately lead to

0

20

40

60

80

2010E 2011E 2012E 2013E 2014E 2015E

系列1

ultimately lead to

margin expansion

and sustainable

growth in the long

term

Page 18: WuXi Pharma Tech - University of Virginia...facility with total 300,000 square feet. Advantage in China Abundant resources and fewer regulatory constraints on animal testing. Multiple

3. High Quality intelligence

� Young, vibrant work

force

� 78% Scientists with

Master Degree

� Highly sought-after

employer on college

campuses in China

� Superior training

program

Page 19: WuXi Pharma Tech - University of Virginia...facility with total 300,000 square feet. Advantage in China Abundant resources and fewer regulatory constraints on animal testing. Multiple

China’s Cost Benefit

Breakdown of CRO costs in China relative to the US: 34.2%

Page 20: WuXi Pharma Tech - University of Virginia...facility with total 300,000 square feet. Advantage in China Abundant resources and fewer regulatory constraints on animal testing. Multiple

IV. Key Risk

� Slower global pharmaceutical growth and cash conservation from small biotech clients

� Exchange risk leads to earnings uncertainty

� The emergence of many new CRO start-ups and expansion of large-scale CROs might lead to fierce pricing wars. WuXi could be pressured to lower its prices in the long run.

Page 21: WuXi Pharma Tech - University of Virginia...facility with total 300,000 square feet. Advantage in China Abundant resources and fewer regulatory constraints on animal testing. Multiple

V. VAR summary

� Interview with Management over summer 2009

Cooperation with Merck Good team workManagement showed clients were Management showed clients were

impressed with customer-driven, high-quality integrated service

09 is the toughest year for the company, but still have new establishment

Page 22: WuXi Pharma Tech - University of Virginia...facility with total 300,000 square feet. Advantage in China Abundant resources and fewer regulatory constraints on animal testing. Multiple

V. VAR summary

� Perspectives from employees� salary

Bachelor Degree: ~3000 RMB/month (US$ 500)

Master Degree: ~5000 RMB Master Degree: ~5000 RMB

Employee working for 3 years� “ I have been working in the company for three

years. It’s development is like a train running at full speed, very amazing. Here, I met top people, work in the top environment and receive top-standard training”

Page 23: WuXi Pharma Tech - University of Virginia...facility with total 300,000 square feet. Advantage in China Abundant resources and fewer regulatory constraints on animal testing. Multiple

VI. Stock PerformancePrice in the past 2 years

Page 24: WuXi Pharma Tech - University of Virginia...facility with total 300,000 square feet. Advantage in China Abundant resources and fewer regulatory constraints on animal testing. Multiple

Financial Data

� Price: US$13.45

� 52-Week Range: US$3.67-US$14.04

� Market Cap (million): US$978 / 72.7

� ROE (2009E) 26.3%

� Net Dbt to Eqty (Dec-2008A) -5.3%

Page 25: WuXi Pharma Tech - University of Virginia...facility with total 300,000 square feet. Advantage in China Abundant resources and fewer regulatory constraints on animal testing. Multiple

Valuation

� laboratory services: stable growth of 16%

CAGR

� Manufacturing revenue: pick up with an � Manufacturing revenue: pick up with an

growth CAGR of 32.4%

� Toxicology services: launch in 2H2010 to act

as a long-term growth driver

Page 26: WuXi Pharma Tech - University of Virginia...facility with total 300,000 square feet. Advantage in China Abundant resources and fewer regulatory constraints on animal testing. Multiple

1) Driven by its cost advantages and ongoing business

expansion, the company’s earnings growth CAGR

will be at 28% over 2009E-2011E vs. its global peer

average of 13.6%,

Valuation :undervalued

average of 13.6%,

2) Higher ROE of 16% in 2010E vs. its peer average of

13%, driven by margin expansion due to WuXi’s shift

towards more higher-margin services.

Page 27: WuXi Pharma Tech - University of Virginia...facility with total 300,000 square feet. Advantage in China Abundant resources and fewer regulatory constraints on animal testing. Multiple

Question?