Wrap Up skenario 1 blok muskulo

7/24/2019 Wrap Up skenario 1 blok muskulo

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WRAP UP SKENARIO 1

“NYERI SENDI SIKU”

Disusun oleh:

KELOMPOK A-5

KETUA : DHANA FITRIA SARI (11!1"#1$

SEKRETARIS: ANNISA A%U RAHMAWATI (11!1"&1$

AN''OTA : AIS%AH KHAIRINA P (11!1"1$

AL)IN ARIANO (11!1"1"$

ANTANIA SARASWATI H(11!1"&*$

AULIA ELMA A++AHRA (11!1"",$

A'US DIAN PRANATA (11!1&5!$

'ER% ALDILATAMA (11!1"115$

.UWITA KARTIKA (11!1"&,$

FAKULTAS KEDOKTERAN

UNIVERSITAS YARSI

2014/2015



SKENARIO

N%ERI SENDI SIKU

Seo/0n l02i 3 l02i 5 40hun 6040n 2e Ru70h S02i4 6en0n 2eluh0n sen6i si2u 6i/0s020n n8e/i

60n 9e/6en8u4 se/40 7en0nu /en40n e/02 (/0ne o 7o;e7en4 < ROM$ se=02 ! 9ul0n iniP060 >e7e/i2s00n isi2 6i4e7u20n >e79en2020n >060 ole?/0non 60n >060 >e7e/i2s00n l09

6i4e7u20n hi>e/u/e2e7i0 Do24e/ 7e79e/i20n o904 0n4i n8e/i (NSAID$ 60n u/i?osu/i?



KATA SULIT

1 Ren40n 'e/02 : .u7l0h 702si70l e/020n 80n 7un2in 6il02u20n sen6i >060 s0l0h s04u 60/i 4i0 >o4on0n 4u9uh 80i4u s0i440l 4/0ns;e/s0l 60n

/on40l

! Me4040/so>h0l0ne0l I: E2s4/e7i40s ine/io/ >060 i9u =0/i 202i& Hi>e/u/i2e7i0 : Ke0600n 6i70n0 0s07 u/04 60/0h 4ini 6i040s #7

" U/i?osu/i? : O904 80n 9e/unsi un4u2 7enelu0/20n 0s07 u/04 7el0lui u/in

5 Ole?/0non : Ton=ol0n uln0/ >060 si2u 040u 9i0s0 6ise9u4 sen6i si2u* NSAID : Non S4e/oi6 An4i Inl07704o/8 D/us 060l0h 2elo7>o2 o904

80n 9e/unsi se900i 0n4i inl070si 0n4i 0n0lesi2 60n 0n4i

>i/e4i2



PERTAN%AAN

1 A>0 80n 7en8e90920n /0s0 n8e/i 60n 9e/6en8u4 >060 sen6i si2u @! il0 n8e/i 6i9i0/20n s0=0 0>0 80n 020n 4e/=06i@ D0n 0>09il0 n8e/i 6i9e/i o904 0>0 80n

020n 4e/=06i @

& A>020h >e7e/i2s00n >enun=0n un4u2 >en802i4 4e/se9u4 @" A>0 80n 7en8e90920n hi>e/u/i2e7i0 >060 >0sien 4e/se9u4 @

5 A>0 s0=0 e=0l0 80n 4i79ul 20/en0 >en802i4 4e/se9u4 @

* A>0 80n 7en8e90920n >e79en2020n >060 ole?/0non@

.AWAAN

1 K0/en0 060n80 >e79en2020n 80n 9e/isi 2/is40l 0s07 u/04 >060 sen6i si2u 80n

6ise90920n oleh >enu7>u20n >/os40l0n6in

! A>09il0 6i9i0/20n s0=0 020n 4e/0s0 le9ih n8e/i 4e/=06i >e79es0/0n >e79en2020n 60n7en0nu 024i;i40s N07un 0>09il0 6i9e/i o904 n8e/i s0=0 n8e/i 60>04 9e/2u/0n

n07un 4e40> 060 >e79en2020n

& 0 Pe7e/i2s00n K060/ As07 U/04

9 Pe7e/i2s00n U/in ? Pe7e/i2s00n L0=u En60> D0/0h (LED$

6 Pe7e/i2s00n ?0i/0n sen6i s8no;i0l

e R06ioloi

" 0 0n802 7en2onsu7si 7020n0n 80n 7en0n6un >u/in 4ini

9 Kel0in0n ene4i? se>e/4i 'ou4 S8n6/o7e Lesshn8h0n 60n Deisiensi A6enosin De07in0se

5 A/4h/i4is 'ou4 :- e/6en8u4 - De707

- Ke7e/0h0n - en202

A/4h/i4is Rhe704oi6 : Ke6u0 40n0n 202u >060 >0i h0/i

* K0/en0 >/os40l0n6in 7enelu0/20n 7e6i04o/-7e6i04o/ inl070si 80n 7en8e90920n

;0so6il040si sehin0 4e/=06i >e79en2020n

HIPOTESIS

Hi>e/u/i2e7i0 060l0h 2e0600n 6i70n0 4inin80 2060/ 0s07 u/04 60/0h 80n 6ise90920n

90n802n80 2onsu7si 7020n0n 80n 7en0n6un >u/in 4ini A>09il0 6i9i0/20n 020n

7en8e90920n 4e/=06in80 >enu7>u20n 2/is40l 0s07 u/04 >060 sen6i sehin0 7eni79ul20n /0s0n8e/i 60n 9e/6en8u4 se/40 7en0nu /en40n e/02 Pe7e/i2s00n 80n 6il02u20n un4u2



7ene0220n 6i0nosis 060l0h >e7e/i2s00n LED 2060/ 0s07 u/04 u/in ?0i/0n s8no;i0l 60n

/06ioloi Pe79e/i0n NSAID 60>04 7enu/0ni /0s0 n8e/i 60n >e79e/i0n u/i?osu/i? 60>04

7enelu0/20n 0s07 u/04 60/0h 7el0lui u/in

SASARAN ELA.AR

1 Me70h07i 60n Men=el0s20n An04o7i Pe/sen6i0n 60n Al04 'e/02

11 M02/os2o>i2

1! Mi2/os2o>i2



! Me70h07i 60n Men=el0s20n As07 U/04

!1 Deinisi

!! Me409olis7e!& E2s2/esi

& Me70h07i 60n Men=el0s20n A/4h/i4is 'ou4&1 Deinisi

&! E4ioloi

&& P04oisioloi 60n P04oenesis&" M0nies40si Klinis

&5 Di0nosis 60n Di0nosis 0n6in

&* Ko7>li20si

&# T040 L02s0n0& Pen?e0h0n

&, P/onosis

" Me70h07i 60n Men=el0s20n NSAID 60n U/i?osu/i?"1 F0/702o2ine4i2 60n F0/702o6in07i2 NSAID

"! In6i20si 60n Kon4/0in6i20si NSAID"& Ee2 S07>in NSAID

"" F0/702o2ine4i2 60n F0/702o6in07i2 U/i?osu/i?

"5 In6i20si 60n Kon4/0in6i20si U/i?osu/i?"* Ee2 S07>in U/i?osu/i?

1 Me70h07i 60n Men=el0s20n An04o7i Pe/sen6i0n 60n Al04 'e/02

11 M02/os2o>i2





A A/4i?ul04io 'lenohu7e/0lis

Tul0n : B0>u4 hu7e/i 6en0n leinoi60lis se/40 l09/u7 leinoi60le

'e/02 sen6i : Fle2si e2s4ensi 096u2si 066u2si Ro40siMe6i0lisRo40si

L04e/0lis



A/4i?ul04io Bu9i4i (A/4i?ul04io hu7e/o uln0/is C 0/4 Hu7e/o/06i0lis$ Tul0n : In?issu/0 4h/o?le0/is uln0 4/o?hle0 hu7e/i 60n0n40/0 o;e0 ?0>u4

0/4i?ul0/is /06ii 60n ?0>i4ulu7 hu7e/i 'e/02 Sen6i : Fle2si 60n e2s4ensi

-O4o4- o4o4 Shun4 : O4o4 80n 7e7>un80i o/io 6e204 6en0n sen6i 60ninse/4io =0uh 60/i sen6i (?on4oh : M /0?hio/06i0lis$

-O4o4- o4o4 S>u/4 : O4o4 80n 7e7>un80i o/io =0uh 60/i sen6i 60n inse/4io6e204

6en0n sen6i (?on4oh : M i?e>s 9/0?hii$O4o4- o4o4 shun4 le9ih 9e/unsi se900i

s409ili404o/ 60/i>060 /o404o/ se60n20no4o4- o4o4 s>u/4 le9ih 9e/unsi se900i

/o404o/ 60/i>060 s409ilis04o/

B A/4i?ul04io R06io uln0/is P/oi70lis Tul0n : In?issu/0 /06i0lisuln0 60n ?0>u4 /06ii

'e/02 sen6i : 4h/o?hoi6e0 040u >i;o4

D A/4i?ul04io R06io Uln0/is 6is40lis Tul0n : In?issu/0 uln0/is /06ii 60n ?0>i4ulu7 uln0e

.enis sen6i : 4/o?hoi6e0

'e/02 sen6i : >/on0si 60n su>in0si

E A/4i?ul04io R06io?0/>0lis Tul0n : 0i0n 6is40l Os R06ius 60n oss0?0/>0les>/oi70lis 2e?u0li os

>i/io/7e 'e/02 sen6i : Fle2si e2s4ensiA96u2si uln0/is

F A/4i?ul04io ?0/>o7e40?0/>0les

A/4i?ul04io ?0/>o7e40?0/>0les I Tul0n : An40/0 Me40?0/>0les 60n 4/0>eiu7

'e/02 sen6i : Fle2si e2s4ensi 096u2si 066u2si o>osisi 60n /e>osisi

A/4i?ul04io ?0/>o7e40?0/>0les II Tul0n : An40/0 Me40?0/>0le II 3 ) 6en0n Os B0/>i 6e/e40n 6is40lis

'e/02 sen6i : 'ese/

' A/4i?ul04io Me40?0/>o>h0l0ne0lis

A/4 Me40?0/>o>h0l0ne0lis I Tul0n : An40/0 Os 7e40?0/>0l I 60n >h0l0n I

'e/02 sen6i : Fle2si e2s4ensi se6i2i4 096u2si 60n 066u2si

A/4 Me40?0/>o>h0l0ne0lis II s07>0i ) Tul0n : An40/0 OS 7e40?0/>0l II 60n ) 6en0n Ph0l0nII 60n )



'e/02 sen6i : Fle2si e2s4esi 096u2si 066u2si 60n si/2u76i2si

H A/4i?ul04iones in4e/>h0l0ne0lis

Tul0n : An40/ >h0l0nes

'e/02 sen6i : Fle2si 60n e2s4ensi

A A/4i?ul04io ine/io/is li9e/i (0/4i?ul04io ?o0e$

• Tul0n : A?e409ulu7 60n ?0>u4 e7u/i

• 'e/02 sen6i: Fle2si e2s4ensi 096u2si 066u2si en6o/o40sie2so/o40si



A/4i?ul04io enus

• Tul0n : Bon68lus 7e6i0lis e7o/is 60n ?on68lus7e6i0lis 4i9i0e

• 'e/02 sen6i : Fle2si e2s4ensi /o40si 7e6i0lis le2si l04e/0lis

B A/4i?ul04io 4i9io i9ul0/is• Tul0n: F0?ies 0/4i?ul0/is i9ul0/is 6en0n 0?ies 0/4i?ul0/is ?0>i4is i9ul0e

• 'e/02 sen6i: 'ese20n 2e 040s 60n 2e 900h

D A/4i?ul04io 40lo?/ul0lis

• Tul0n: An40/0 4/o?hle040li 60n len2un 80n 6i9en4u2 oleh 70leoli oss0 ?/u/is

• 'e/02 sen6i: Pl0n40/ Flei Do/si Flei In;e/sio 0n6 E;e/sio

E A/4i?ul04io Pe6is

A/4i?ul04io 40lo?0l?0ne0

• Tul0n:Os 40lus 60n Os ?0l?0neus

• 'e/02 sen6i:li6in

F A/4i?ul04io 40lo?0l?0neon0;i?ul0/is

• Tul0n:Os 40lus Os ?0l?0neus 60n Os ?u9oi6eu7

• 'e/02 sen6i: 'ese/ 60n /o40si

' A/4i?ul04io ?0l?0neo?u9oi6e0

• Tul0n: Os ?0l?0neus 60n Os ?u9oi6eu7

• 'e/02 sen6i: 'ese/ 60n se6i2i4 /o40si

H A/4i?ul04io 40/so7e4040/s0les• Tul0n: Os 40/si 60n Os 7e4040/si

• 'e/02sen6i: Pl0n0

I A/4i?ul04io Me4040/so>h0l0ne0les

• Tul0n: Os 7e4040/si 60n Os >h0l0ne0les

• 'e/02 sen6i: le2si e2s4ensi 096u2si 066u2si

. A/4i?ul04iones In4e/>h0l0ne0les Pe6is

• Tul0n: In4e/ >h0l0ne0les

•'e/02 sen6i : le2si 60n e2s4ensi



.enis-=enis 'e/020n Sen6i :

1 S8n0/4h/osisSen6i 80n 4i602 9e/e/02 s070 se20li Sen6i ini 6i>e/s04u20n oeh =0/in0n i204

>0604 i9/os0 e/60s0/20n 2o7>osisi 60/i 90h0n 80n 7enisi >e/4e7u0n 2e6u0

sen6i 6i90i 7en=06i :0 Su4u/0 6i0n40/0 4ul0n 4e/60>04 =0/in0n i9/os0 80n 4i>is se20li ?on4oh: su4u/0

s0i40lis su4u/0 l0796oi6e0 su4u/0 ?o/onoi6e0

9 S8n6es7osis 6i0n40/0 4ul0n 4e/60>04 =0/in0n i9/os0(li07en4u7<7e79/0n0$ ?on4oh: s8n6es7osis /06io-uln0/is Oss0 4i9i0i9ul0

oss0 7e40?h0/>0lis

? S8n?/on6/osis ( 0/4i?ul04ion ?0/4il0oh80lin $ 6i0n40/0 4ul0n 4e/60>04

>e/s079un0n 4ul0n /00n ?on4oh: s87>hisis >u9is s87>hisis70nu9/iu7s4e/ni

6 S?in6enl8sis s04u 4ul0n 80n 70su2 2e 60l07 ?el0h 4ul0n

e '07>hosis 4ul0n 80n 9e/9en4u2 se>e/4i 40n6u2 60n 70su2 2e 60l07 lu90n4ul0n ?on4oh: ii 60n e/0h07

! A7>i0/4hosis



Sen6i 80n 9e/e/02n80 se6i2i4 Bon4ohn80 060l0h sen6i 6i 0n40/0 9060n-9060n

;e/4e9/0 80n 9e/6e2040n se>e/4i A/4 S0?/oili0?0 Bon4oh l0in 060l0h 4ul0n

/usu2

& Di0/4h/osis

Sen6i 80n 60>04 9e/e/02 9e90s Me/u>020n sen6i 80n 4e/60>04 /on0 6i0n40/02e6u0 4ul0n P060 0/4i?ul04ion s8no;i0lis 4e/60>04: B0/4il0o 0/4i?ul0/is B0;i40s

0/4i?ul0/is Dis?us 0/4i?ul0/is Menis?us 0/4i?ul0/is L09/u7 0/4i?ul0/e B0>sul0

0/4i?ul0/is Me79/0n0 i9/os0 Me790/0n s8no;i0lis Pli?0 s8no;i0lis )illis8no;i0lis S8no;i0 Li07en40 4e/6i/i 60/i: Li07en4u7 e4/0?0>sul0/is

Li07en4u7 ?0>sul0/is 60n Li07en4u7 in4/0?0>sul0/is

e/60s0/20n 9en4u2 >e/7u200n sen6i 60n 4i>e >e/e/020n :

0 A/4h/oi6e0 (li6in$ 6ise9u4 =u0 sen6i lun?u/ (sen6i >l0n0$ 7e/u>020n

>e/sen6i0n 80n 7e7un2in20n e/02 /o40si >060 s04u 9i60n 6040/ Ke>0l0 sen6i

60n le2u2 sen6i /040 is0 20/en0 07>i04h/osis Bon4oh: 0/4 In4e/?0>0les 0/4In4e/40/s0les 0/4 S4e/no?l0;i?ul0/is hu9un0n 4ul0n >e/e/l0n0n 202i

9 'inl87us (hin$ 6ise9u4 =u0 sen6i ensel 7e/u>020n >e/sen6i0n 80n

7e7un2in20n e/020n s04u 0/0h An40/0 >e/7u200n 2on;e2s 60n 2on20

Bon4oh: 0/4 Bu9i4i 0/4 T0lo?/u/0les 0/4 In4e/>h0l0nes sen6i si2u 0n40/0 4ul0nlen0n 040s 60n 4ul0n h0s40

? Pi;o4 (4/o?hoi6e0$ 7e/u>020n >e/7u200n sen6i ;e/4i?0l Bon4oh: 0/4 A4l0n4o

0i0lis 0/4 T/o?hoi6e0 (/06iouln0/is >/o2si70lis$

6 Elli>soi6e0 (?on68loi6e0$ 6ise9u4 =u0 sen6i >u40/ 7e/u>020n >e/sen6i0n 80n7e7un2in20n e/020n 9e/>u40/ (/o40si$ Pe/7u200n sen6i 9e/9en4u2 eli>

Bon4oh: 0/4 R06io?0/>0l hu9un0n 4ul0n 4en2o/02 6en0n 4ul0n 9el020n I

(04l0s$

e S>he/oi6e0 (0 90ll 0n6 so?2e4$ 6ise9u4 =u0 sen6i >elu/u 7e/u>020n >e/sen6i0n

80n 7e7un2in20n >e/e/020n 2e se0l0 0/0h Ke>0l0 sen6i se>e/4i 9en4u2 9ol0

70su2 2e60l07 le2u2 sen6i 80n 60l07 Bon4oh: 0/4 Bo0e hu9un0n 4ul0nlen0n 040s 6en0n 4ul0n 9eli204

Sell0/is (s066le$ 6ise9u4 =u0 sen6i >el0n0 7e/u>020n >e/sen6i0n 80n7e7un2in20n 9e9e/0>0 e/020n /o40si n07un 4i602 2e se0l0 0/0h Ke>0l0

sen6i 60n le2u2 sen6i se>e/4i o/0n 6u6u2 6i040s >l0n0 2u60 Bon4oh: 0n40/0

4/0>eiu7 60n 7e40?0/>0l hu9un0n 4ul0n 4el0>02 40n0n 60n =0/i 40n0n

i60n 2h080l 4u9uh: i60n ?o/on0l 7e790i 4u9uh 7en=06i 0n4e/io/ 60n >os4e/io/ su79u

e/02n80 s0i440l



i60n s0i440l 7e790i 4u9uh 7en=06i 6e4/0 60n sinis4/0 su79u e/02n80

/on40l i60n 4/0ns;e/s0l 7e790i 4u9uh 7en=06i su>e/io/ 60n ine/io/ su79u

e/02n80 ;e/4i?0l

'e/02 sen6i 4u9uh: Fle2si e/020n 80n 7en6e20420n 90i0n 60/i 4ul0n 80n 7e79en4u2 sen6i

E2s4ensi e/02 9e/l00n0n 60/i le2si

A96u2si e/02 0/0h sisi 7en=0uhi 9i60n s0i440l

A6u2si e/02 80n 9e/l00n0n 0/0h 6en0n 096u2si<7en6e204i 9i60n

s0i440l En6o/o40si e/02 9e/>u40/ l04e/0l 3 0n4e/io/ 3 7e6i0l

E2so/o40si e/02 9e/>u40/ 7e6i0l 3 0n4e/io/ 3l04e/0l

L04e/ole2si e/02 le2si 2e 0/0h s07>in

Si/2u76i2si 09un0n e/02 /o40si (le2si l04e/ole2si e2s4ensi$

1! Mi2/os2o>i2

Pe/sen6i0n 060l0h 4e7>04 9e/4e7un80 6u0 040u 4i0 unsu/ 4ul0n 90i2 4ul0n 040u4ul0n /00n 6i204020n se900i sen6i 040u 0/4i2ul0si Sen6i 4e7>o/e/ 4e/60>04

sel070 70s0 >enu79uh0n : 7is0ln80 e>iisis 4ul0n >0n=0n 7en804u 6en0n

90i0n 9040n 4ul0n 7el0lui 4ul0n /00n hi0lin 60/i 6is2us e>iisis Sen6i

6e7i2i0n 7enhil0n 9il0 >enu79uh0n 9e/hen4i 60n e>iisis 7en804u 6en0n 90i0n 9040n Te40>i 2e90n8020n sen6i 9e/si04 >e/70nen 60n 60>04 6iolon20n

9e/60s0/20n ?i/i susun0nn80 7en=06i & olon0n u4070 : i9/os0 20/4il0inos0

60n s8no;i0l

Kl0sii20si Pe/sen6i0n

0 Sen6i Fi9/os0

Sen6i ini 6i>e/s04u20n oleh =0/in0n i204 >0604 i9/os0 il0 >en804u0n ini s0n042u04 sen6i ini 6ise9u4 su4u/0 Su4u/0 h0n80 4e/60>04 >060 4en2o/02 60n 4i602

9e/si04 >e/70nen 20/en0 =0/in0n i9/os0 >eni204 i4u 60>04 6i0n4i oleh 4ul0n

6i2e7u6i0n h0/i Pen804u0n 4ul0n 80n 6ih0sil20n i4u 6i2en0l se900i sinos4osisSen6i >060 4ul0n 80n 6i>e/s04u20n oleh =0/in0n i204 i9/os0 80n =0uh le9ih

90n802 60/i>060 80n 4e/60>04 >060 su4u/0 6ise9u4 sin6es7osis

9 Sen6i Tul0n R00nSen6i ini se/in 6i204020n se900i sen6i 20/4il0inos0 se2un6e/ un4u2

7e79e6020nn80 60/i sen6i >/i7e/ >0lin =el0s 6i4un=u20n se900i ?on4oh olehsen6i 6i0n40/0 9060n-9060n ;e/4e9/0 80n 9e/6e2040n Pe/7u200n 4ul0n 80n

9e/h060>0n 6il0>isi le790/-le790/ 4ul0n /00n hi0lin 80n se?0/0 e/04

6i>e/s04u20n oleh le7>en i9/o20/4il0o Si7iisis se>e/4i sen6i >u9is 60n

70nu9/ios4e/n0l 7e/u>020n ?on4oh sen6i 20/4il0inos0 se2un6e/



? Sen6i Sino;i0l

Se90i0n 9es0/ sen6i 2i40 060l0h sen6i sino;i0l Pe/7u200n 4ul0n 80n 9e/sen6i

6iselu9uni oleh 4ul0n /00n 80n lun02 60n li?in P060 sen6i ini 4ul0n-4ul0n6i40h0n 7en=06i s04u si7>0i sen6i Si7>0i sen6i 7en804u20n 4ul0n

l0>is0n lu0/ si7>0i -G =0/in0n i204 >0604 2ol0en 80n 7en804u 6en0n

>e/ios4eu7 l0>is0n 60l07 si7>0i -G 7e79/0n sino;i0l (7e79040si /on0 sen6i$

Me79/0n sino;i0l: 7e79/0n ;0s2ul0/ 4i>is 7en0n6un 20>ile/-2e>ile/

1 Me79/0n sino;i0l 80n 7en=ulu/ 2e60l07 /on0 sen6i -G li>040n 20s0/

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BO-1! W0l0u>un >0/06i70 BO-! 7e7ili2i 2eunul0n 060 9e9e/0>0 isu

60n o9se/;0si 4en40n eni7- eni7 BO 60n NSAID 80n h0/us 6i?e/704i 60n60>04 7en8e90920n i7>li20si 2e070n0n BO-! inhi9i4o/

Pe/lin6un0n l079un oleh BO-1 60n 0s4/o>04i 7el0lui h079040n BO-1

4i602 sese6e/h0n0 i4u A24i;i40s BO-! 6i 7u2os0 l079un 020n 7e790n4u >060 9e9e/0>0 si4u0si

BO-! 6i in6us oleh 060n80 lu20 6i l079un 60n 4e/lih04 6i>ini/ 4u202 >060

70nusi0 60n BO-! inhi9i4o/ 7enh07904 >en8e79uh0n 4u202 >060 70nusi0

60n 9in040n A24i;i40s BO-! 7enun4un20n unsi in=0l BO-! 7e7ili2i si04

2ons4i4u4i 6i in=0l 60n 6i4/i9usi in4/0/en0l 60n /eul0si >en04u/0n 2060/ 0/07

6i0n0> 90h0 BO-! 7e790n4u >en04u/0n he7o6in07i20 in=0l >060

9e9e/0>0 si4u0si Me20nis7e 0n0lesi2 BO-! inhi9i4o/ 4i602 60>04 6i0n0> se>ele se909 BO-

! inhi9i4o/ 7enu/0ni /0s0 n8e/i 90h20n >060 2on6isi noninl0704o/i

F0/702o2ine4i2

NSAID 7e7ili2i 90n802 2es0700n 60l07 0/702o2ine4i2 %0n >0lin >en4in060l0h >e/9e600n >0/uh 024u 6en0n /en40n 60/i 1 =07 un4u2 4ol7e4in s07>0i

5 =07 un4u2 >i/o2si207 7e7>en0/uhi /e2uensi 6osis 60n 2e40040n 4e/0>i

"! In6i20si 60n Kon4/0in6i20si NSAIDIn6i20si: 6iin6i20si20n un4u2 >en6e/i40 n8e/i /in0n s07>0i se60n 60n >en802i4

6en0n >e/060n0n

Kon4/0in6i20si : 6ihin60/i >060 >en6e/i40 0nu0n h04i 040u in=0l 20/en0 o904 ini6i9u0n 7el0lui o/0n 4e/se9u4 sehin0 60>04 7e7>e/9e/04 2el0in0n unsi h04i

60n in=0l I9u h07il 4/i7es4e/ 2e4i0 60n i9u 7en8usui =u0 7e/u>020n

2on4/0in6i20si >e79e/i0n o904 olon0n ini 20/en0 o904 ini 60>04 7en8e90920n2e?0?040n >060 908i 80n 6i20n6un 60n 6i9u0n 7el0lui 0i/ susu An02 6i 900h

1" 40hun 4i602 6is0/0n20n 7ene/i70 o904 ini

"& Ee2 S07>in NSAID Ee2 >060 l079un 60/i NSAID

Keluh0n 2e?il: Mu0l 6is>e>si0 0no/e2si0 /0s0 s02i4 6i l079un l04ulen

6i0/e 4e/=06i >060 1-* >0sien Un4u2 7enu/0ni ee2 ini NSAIDse90i2n80 6i7020n 6en0n 7020n0n 040u susu 2e?u0li o904 6en0n en4e/i?

?o04e6 =0n0n 6i7020n 6en0n susu 040u 0n40?i6 NSAID 60>04 7en8e90920n >en802i4 in=0l 4e/70su2 insuisiensi /en0l 02u4

hi>e/20le7i0 ne2/osis >0>il0/i in=0l D040 2linis sin6/o7 in=0l:

7enin204n80 se/u7 2/e04inin hi>e/20le7i0 7enin204n80 4e20n0n 60/0h

e6e70 >eie/0l >en0790h0n 9e/04 9060n



"" F0/702o2ine4i2 60n F0/702o6in07i2 U/i?osu/i? A60 ! 2elo7>o2 o904 >en802i4 >i/0i 80i4u o904 80n 7enhen4i20n >/oses

inl070si02u4 7is0ln80 2ol2isin enil9u40on o2sien09u40on 60n in6o7e40sin 60n

o904 80n 7e7>en0/uhi 2060/ 0s07 u/04 7is0ln80 >/o9enesi6 0llo>u/inol 60n

sulin>i/0on

1 Kol2isinA60l0h su04u 0n4i-inl070si 80n uni2 80n 4e/u4070 6iin6i20si20n >060 >en802i4 >i/0i

O904 ini 7e/u>020n 0l20loi6 Bol?hi?u7 0u4u7n0le se=enis 9un0 leli

F0/702o6in07i2

Si04 0n4i/060n 2ol2isin s>esii2 4e/h060> >en802i4 >i/0i 60n 9e9e/0>0 0/4/i4is un4u2 /060n u7u7 o904 ini 4i602 ee24i Kol2isin 4i602 7e7ili2i ee2 0n0lesi? P060

>en802i4 >i/0i 2ol2isin 4i602 7enin20420n e2s2/esi sin4esis 040u /060n 0s07 u/04

60l07 60/0h O904 ini 9e/i2040n 6en0n >/o4ein 7i2/o4u9ul0/ 60n 7en8e90920n

6e>oli7e/0si 60n 7enhil0nn80 7i2/o4u9ul i9/il0/ /0nulosi4 60n sel 9e/e/02 l0inn80

H0l ini 7en8e90920n >enh079040n 7i/0si /0nulosi4 2e 4e7>04 /060n sehin0

>ele>0s0n 7e6i04o/ 0n4iinl070si 6i4e20n Kol2isin 7en?e0h >enle>0s0n li2o>/o4ein

60/i leu2osi4 >060 >0sien ou4 7en8e90920n n8e/i 60n /060n sen6i

F0/702o2ine4i2

A9so/9si 7el0lui s0lu/0n ?e/n0 90i2 O904 ini 6i6is4/i9usi20n se?0/0 lu0s 60l07 =0/in0n

4u9uh K060/ 4ini 9e/060 6i 60l07 in=0l h04i li7>0 60n s0lu/0n ?e/n0 4e40>i 4i602

4e/60>04 6i 60l07 o4o4 /0n20 =0n4un 60n o402 Se90i0n 9es0/ 6ie2s2/esi20n 60l07

9en4u2 4in=0 1-! 7el0lui u/in P060 >0sien >en802i4 h04i le9ih 90n802 7el0lui u/in

Kol2isin 60>04 6i4e7u20n 60l07 leu2osi4 60n u/in se6i2i4n80 un4u2 , h0/i se4el0h su04u

sun4i20n I)

"5 In6i20si 60n Kon4/0in6i20si

In6i20si

Kol2isin 7e/u>020n un4u2 o904 >i/0i oleh 20/en0 i4u >e79e/i0n h0/us 6i9e/i20nse?e>04n80 >060 00l se/0n0n 60n 6i4e/us20n s07>0i e=0l0 hil0n 040u 4i79ul

ee2 s07>in 80n 7en0nu il0 o904 4e/l0lu 4e/l07904 ee24i;i40sn80

2u/0n Kol2isin =u0 9e/un0 un4u2 >/oil024i2 se/0n0n >en802i4 >i/0i 040u

7enu/0ni 9e/04n80 se/0n0n 60n o904 ini =u0 60>04 7en?e0h se/0n0n 80n6i?e4us20n oleh o904 u/i2osu/i2 60n 0lo>u/inol Un4u2 >/oil02sis ?u2u>

6i9e/i20n 6osis 2e?il

Kon4/0in6i20si

P0sien 6en0n 0nu0n in=0l 0nu0n h04i 60n 0nu0n 0s4/oin4es4in0l

"* Ee2 S07>inEe2 s07>in 80n >0lin se/in 60/i 2ol2hisin 060l0h 7un40h 7u0l 60n 6i0/e

60>04 7en0nu 4e/u4070 6en0n 6osis 702si70l il0 ee2 4e/=06i >eno9040nh0/us 6ihen4i20n 0l0u>un ee2 4e/0>i 9elu7 4e/?0>0i De>/esi su7su7 4ul0n

>u/>u/0 neu/i4is >e/ie/ 7io>04i 0nu/i0 0lo>esi0 0nu0n h04i /e02si 0le/i

60n ?oli4is he7o/0i2 4e/=06i 20/en0 6osis 80n 9e/le9ih0n 60n >060 >e79e/i0n

I) 0nu0n e2s2/esi 02i904 2e/us020n in=0l 60n 2o79in0si 2e0600n 4e/se9u4



Kol2isin h0/us 6i9e/i20n h04i-h04i >060 >0sien usi0 l0n=u4 le70h 040u >0sien

6en0n 0nu0n in=0l 20/6io;0s2ul0/ 60n s0lu/0n ?e/n0

DAFTAR PUSTAKA

0790n Se4i8oh06i622 (!1"$ u2u A=0/ Il7u Pen802i4 D0l07 e6isi )I .ili6 III .020/40

'un00n S' Se4i09u68 R N0/i0l6i (!#$ F0/702oloi 60n Te/0>i e6 5 .020/40 : FKUI

Leeson BRol0n6 An4hon8 A P0>0/o (1,,*$ u2u A=0/ His4oloi E6 ) .020/40: E'B

Kei4h L Moo/e A/4hu/ F D0lle8 (!1&$ An04o7i e/o/ien40si Klinis E6 ) .020/4/0 : E/l0n0

P0ulsenFCW0s?h2eF (!1!$ So9o440 : 04l0s 0n04o7i 70nusi0 e6!& =ili6 1 C ! .020/40 : E'B

h44>:<</e>osi4o/8usu0?i6<9i4s4/e07<1!&"5*#,<&1!*<"<Bh0>4e/!II>6 6i02ses >060 ,

Se>4e79e/ !15

http://repository.usu.ac.id/bitstream/123456789/31268/4/Chapter%20II.pdf






h44>:<<6iili9uni7us0?i6<iles<6is21<1!5<=4>4uni7us-6l-/in0=uli0n-*!&&-!-909ii>6 6i02ses

>060 , Se>4e79e/ !15

9in0/2e72esoi6!F&F>670?4&D>/o?ess!*6i6&DMT"L7h;6'>97s

&DCusAF=BNERH,D65u/Q/R1)"H)7iT87hWACsi!nn=Ln5'=-=T,IhM/&T

6i02ses >060 , Se>4e79e/ !15

http://digilib.unimus.ac.id/files/disk1/125/jtptunimus-gdl-rinajulian-6233-2-babii.pdf

http://digilib.unimus.ac.id/files/disk1/125/jtptunimus-gdl-rinajulian-6233-2-babii.pdf

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