1
(n¼2) had a median OS of 20m vs 4.8 in patients who did not receive adrenal RFA (p¼0. 65). Extra-hepatic mets were present before 1st DEB TACE in 81% of pts vs after 1st DEB TACE in 19%; median OS-Emb 6.7 vs 7.7 m (p¼0.9). Child-Pugh Class A, B and C stage were present in 62.3%, 29% and 8.7% of the pts with corresponding median OS-Emb were 10.5m, 5.2m and 1.6m respectively (po0.001). Okuda stage I, II and III were present in 31.9%, 58% and 10.1% of the pts with corresponding median OS- Emb were 10.6m, 7.4m and 1.6m respectively (po0.001). 50.7% of pts had portal vein thrombosis (PVT) with median OS-Emb was 4.9m vs 12.1m who did not have PVT (p¼0.1). 44.9% of pts received sorafenib systemic chemotherapy with median OS-Emb was 10.5 m vs 5.5 m who did not receive the sorafenib (p¼0.1). The following variables were significant prognostic indicators of survival on multivariate analysis; site of mets, Child-Pugh class and Okuda stage. Conclusion: mHCC patients in Child-Pugh A, isolated mets to adrenal or lung or portahepatic node and Okuda stage I benefited most from DEB TACE therapy. Survivals and Predictive Factors of Metastatic Hepato- cellular Carcinoma (MhCC) Treated with Doxorubicin Drug-Eluting Beads Transcatheter Chemoembolization (DEB TACE) Survival Analysis Location of mets Adrenal gland only Isolated portal hepatic lympha- denopathy (LN) % (Number) 8.7 % (6) 20.3% (14) Median OS from DEB TACE (m) 20 20.3 P value 0.002 Survivals and Predictive Factors of Metastatic Hepato- cellular Carcinoma (MhCC) Treated with Doxorubicin Drug-Eluting Beads Transcatheter Chemoembolization (DEB TACE), continued Cardio- phrenic or retroperi- toneal or other group LN Lungs only Bones only Others or multiple locations 27.5% (19) 11.6% (8) 2.9% (2) 29% (20) 5.2 30.8 10.5 4.4 Abstract No. 403 Withdrawn Educational Exhibit Abstract No. 404 Parathyroid venous sampling: a pictorial review of normal and variant applied venous anatomy G.N. Babu, J.W. Pinchot, J. Fallucca, P. Dalvie, J.C. McDermott, O. Ozkan; Radiology, University of Wisconsin - Madison, Madison, WI Learning Objectives: To facilitate widespread utilization of the parathyroid venous sampling, this pictorial assay reviews normal anatomy and its variants of considerable clinical importance. We will also present the problems and challenges they pose for the interventional radiologist. Background: Parathyroid venous sampling for para-thyroid hormone (PTH) is a highly promising method for localization and diagnosis of parathyroid tumors. Sampling of small veins is the goal. The reported sensitivity of parathyroid venous sampling is 70-80%. However, patients with congenital variation in anatomy and also those with distorted anatomy due to previous surgery can sometime present significant challenge to successful completion of bilateral parathyroid venous sampling resulting in false negative test. Clinical Findings/Procedure Details: Technical Details: This pictoral review presents parathyroid venous anatomy along with the details of catheterization and retrograde venography of the parathyroid venous bed wherever necessary. In the entire series of no significant complication has occurred. Normal Anatomy and Variants: The thyroid venous bed is composed of: (a) a diffusely anastomosing, valveless plexus of veins arising from and investing the thyroid gland; and (b) paired, draining superior, middle and inferior thyroid veins. - Superior thyroid veins - Middle thyroid veins - Inferior thyroid veins - most common patterns - Thymic mediastinal veins - Azygos vein and left superior intercostal veins - Few confusing veins such as anterior jugular and the vertebral veins as well as mediastinal veins. - Interesting cases Conclusion and/or Teaching Points: The roentgenographic anatomy of parathyroid veins is presented. As usual with venous anatomy, variations from the preceding standard description are common. Parathyroid drainage occurs predominantly via the inferior thyroid vein. Although inferior thyroid drainage is variable, bilateral samples could be obtained in a high percentage of cases. Probably least important for parathyroid drainage, the superior thyroid was the most constant and predictable of the thyroid veins. Abstract No. 405 Level of occlusion of a resorbable hydrogel and microsphere in a rabbit renal model L. Weng 1 , P. Rostamzadeh 1 , N. Rostambeigi 1 , M. Bravo 2 , J. Carey 2 , J. Golzarian 1 ; 1 Radiology, University of Minnesota, Minneapolis, MN; 2 North American Science Associates, Brooklyn Park, MN Purpose: To compare the level of occlusion for a bioresorbable hydrogel and microspheres in a renal embolization model. Materials and Methods: Four adult rabbits (New Zealand, 2.9- 3.3 kg) were used. Bioresorbable hydrogel microspheres (100-300 mm), prepared from carboxymethyl chitosan (CCN) and oxidized carboxymethyl cellulose (OCMC, 25% theoretical oxidation degree), JVIR Posters and Exhibits S171 Posters and Exhibits

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(n¼2) had a median OS of 20m vs 4.8 in patients who did not

receive adrenal RFA (p¼0. 65). Extra-hepatic mets were present

before 1st DEB TACE in 81% of pts vs after 1st DEB TACE in

19%; median OS-Emb 6.7 vs 7.7 m (p¼0.9). Child-Pugh Class A,

B and C stage were present in 62.3%, 29% and 8.7% of the pts

with corresponding median OS-Emb were 10.5m, 5.2m and 1.6m

respectively (po0.001). Okuda stage I, II and III were present in

31.9%, 58% and 10.1% of the pts with corresponding median OS-

Emb were 10.6m, 7.4m and 1.6m respectively (po0.001). 50.7%

of pts had portal vein thrombosis (PVT) with median OS-Emb

was 4.9m vs 12.1m who did not have PVT (p¼0.1). 44.9% of pts

received sorafenib systemic chemotherapy with median OS-Emb

was 10.5 m vs 5.5 m who did not receive the sorafenib (p¼0.1).

The following variables were significant prognostic indicators of

survival on multivariate analysis; site of mets, Child-Pugh class

and Okuda stage.

Conclusion: mHCC patients in Child-Pugh A, isolated mets to

adrenal or lung or portahepatic node and Okuda stage I benefited

most from DEB TACE therapy.

Survivals and Predictive Factors of Metastatic Hepato-cellular Carcinoma (MhCC) Treated with DoxorubicinDrug-Eluting Beads Transcatheter Chemoembolization(DEB TACE)

Survival Analysis

Location of mets Adrenal glandonly

Isolated portalhepatic lympha-denopathy (LN)

% (Number) 8.7 % (6) 20.3% (14)Median OS fromDEB TACE (m)

20 20.3

P value 0.002

Survivals and Predictive Factors of Metastatic Hepato-cellular Carcinoma (MhCC) Treated with DoxorubicinDrug-Eluting Beads Transcatheter Chemoembolization(DEB TACE), continued

Cardio-phrenicor retroperi-toneal orothergroup LN

Lungsonly

Bonesonly

Othersormultiplelocations

27.5% (19) 11.6% (8) 2.9% (2) 29% (20)5.2 30.8 10.5 4.4

Abstract No. 403

Withdrawn

Educational Exhibit Abstract No. 404

Parathyroid venous sampling: a pictorial review ofnormal and variant applied venous anatomyG.N. Babu, J.W. Pinchot, J. Fallucca, P. Dalvie,J.C. McDermott, O. Ozkan; Radiology, University ofWisconsin - Madison, Madison, WI

Learning Objectives: To facilitate widespread utilization of the

parathyroid venous sampling, this pictorial assay reviews normal

anatomy and its variants of considerable clinical importance. We

will also present the problems and challenges they pose for the

interventional radiologist.

Background: Parathyroid venous sampling for para-thyroid

hormone (PTH) is a highly promising method for localization

and diagnosis of parathyroid tumors. Sampling of small veins is

the goal. The reported sensitivity of parathyroid venous sampling

is 70-80%. However, patients with congenital variation in

anatomy and also those with distorted anatomy due to previous

surgery can sometime present significant challenge to successful

completion of bilateral parathyroid venous sampling resulting in

false negative test.

Clinical Findings/Procedure Details: Technical Details: This

pictoral review presents parathyroid venous anatomy along with

the details of catheterization and retrograde venography of the

parathyroid venous bed wherever necessary. In the entire series of

no significant complication has occurred. Normal Anatomy and

Variants: The thyroid venous bed is composed of:

(a) a diffusely anastomosing, valveless plexus of veins arising

from and investing the thyroid gland; and

(b) paired, draining superior, middle and inferior thyroid veins.

- Superior thyroid veins

- Middle thyroid veins

- Inferior thyroid veins

- most common patterns

- Thymic mediastinal veins

- Azygos vein and left superior intercostal veins

- Few confusing veins such as anterior jugular and the vertebral

veins as well as mediastinal veins.

- Interesting cases

Conclusion and/or Teaching Points: The roentgenographic

anatomy of parathyroid veins is presented. As usual with venous

anatomy, variations from the preceding standard description are

common. Parathyroid drainage occurs predominantly via the

inferior thyroid vein. Although inferior thyroid drainage is

variable, bilateral samples could be obtained in a high percentage

of cases. Probably least important for parathyroid drainage, the

superior thyroid was the most constant and predictable of the

thyroid veins.

Abstract No. 405

Level of occlusion of a resorbable hydrogel andmicrosphere in a rabbit renal modelL. Weng1, P. Rostamzadeh1, N. Rostambeigi1, M. Bravo2,J. Carey2, J. Golzarian1; 1Radiology, University ofMinnesota, Minneapolis, MN; 2North American ScienceAssociates, Brooklyn Park, MN

Purpose: To compare the level of occlusion for a bioresorbable

hydrogel and microspheres in a renal embolization model.

Materials and Methods: Four adult rabbits (New Zealand, 2.9-

3.3 kg) were used. Bioresorbable hydrogel microspheres (100-300

mm), prepared from carboxymethyl chitosan (CCN) and oxidized

carboxymethyl cellulose (OCMC, 25% theoretical oxidation degree),

JVIR ’ Posters and Exhibits S171

Posters

andExhibits