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Welcome Back!• Current Event?• 4.2 Bellringer• Film advertisements• Membranes (10:40)• Work on HW or finishing filming (time
permitting)
• HW: Draw a representation of a membrane, showing all parts. NOTE that we no longer have time to build one – so ignore the building instructions
Membranes
PLASMA MEMBRANE- keeping it all together
• Isolates the cell from external world• Regulates entry and exit to the cell
• Made up of phospholipids
• The 2 layers of phospholipid molecules are called the phospholipid bilayer
Phosphate
Fatty acid tails
1 phospholipid
Plasma membrane• Called a fluid mosaic because of the different
parts AND b/c phospholipids move around.
Phospholipid “Sandwich”• phosphates touch
watery sides (“the bread”)
• The fatty acids (lipids) “hide” creating the inside of the PM.
phosphate
fatty acids
You are Watery
• The fluid that surrounds all cells in body (interstitial fluid) AND the cytoplasm is:• mostly water• with• salts, proteins, lipids, carbohydrates,
sugars, amino acids, nucleotides, dissolved into it
• Ex: Think liquid in a blister or tears or sweat
Cytoplasm
• Made of:• Function:
–Location of most of the cells metabolic activities (aka: the biochemical reactions that support life)
–Gives cell “fullness”
Define: Mosaic• Mosaic is the art of creating images with an
assemblage of small pieces of colored glass, stone, or other materials
• For example Snowflake Mosaic!
•Other parts of the “mosaic” are…–Proteins do a whole host of things–Cholesterol acts as a stabilizer
Protein Functions
1. Transport
• Move molecules in or out of the cell that can’t cross the membrane
2. Signal Reception
• E.g. receives signals from hormones
• Cell can change activity or gene expression
3. Identifier
• E.g. type A or B blood
• Body can know what cell it is and not to attack it
Blood Transfusions Gone Wrong
4. Cell Connections
• Connect cell to cytoskeleton (interior side)
• Connect cell to other cells (exterior side)
Your Task
• Build a model of the cell membrane out of materials of your choosing
• Think of things you have lying around or waste products (e.g. toilet paper tubes)
• Must include:– Phospholipid bilayer– 4 types of membrane proteins– Labels
• 3D preferred
New Task
• Draw a representation of the membrane
• Include all parts you were supposed to construct and label
Way Super Fancy Example
Phospholipid Head
Phospholipid Tail
Protein
Bring Materials for Friday
•Most of Friday to Build•Due Tuesday