VITAL 3rd Annual Consortium Meeting National Veterinary Research Institute, Pulawy, Poland

Plans and progress on the VITAL Symposium, Workshop and Training

Courses

Mateja Ambrožič and Peter Raspor VITAL 3rd Annual Consortium Meeting

National Veterinary Research Institute, Pulawy, Poland

12th-14th April 2010

WP7 Delivering impact

Biotechnical faculty, University of Ljubljana http://www.bf.uni-lj.si/

Agenda

Structure of the meetingOpening ceremony1st Session: Viruses in food supply chains2nd Session: Virus detection methods3rd Session: Monitoring of viruses in food supply chains4th Session: Risk assessment of viruses in food supply

chains5th Session: Food-borne virus controlTraining course “Control of viruses in food supply chains”Training course “Monitoring of viruses in food supply

chains”Workshop “Taking forward new development in

monitoring and control of viruses in food supply chains” Financial structure

http://www.bf.uni-lj.si/









Structure of the meeting Version A

1st Day

Opening ceremony 2 Plenary lectures

2nd Day1st Session:Viruses in food supply chains

2nd Session: Virus detection methods

3rd Session: Monitoring of viruses in food supply chains

Presentation of VITAL Guidance Manuals










Structure of the meeting Version A

3rd Day 4th Session:

Risk assessment of viruses in food supply chains

5th Session: Food-borne virus control

Training course: “Control of Viruses in Food Supply Chains” Training course: “Monitoring of Viruses in Food Supply Chains”

4th Day Workshop:“Taking Forward New Developments in Monitoring and Control of Viruses in Food Supply Chains”










Structure of the meeting Version B

1st Day

Opening ceremony 2 Plenary lectures

2nd Day1st Session:Viruses in food supply chains

2nd Session: Virus detection methods

3rd Session: Monitoring of viruses in food supply chains

Presentation of VITAL Guidance Manuals

Training course: “Control of Viruses in Food Supply Chains”










Structure of the meeting Version B

3rd Day 4th Session:

Risk assessment of viruses in food supply chains

5th Session: Food-borne virus control

Training course: “Monitoring of Viruses in Food Supply Chains”

3rd Day Workshop:“Taking Forward New Developments in Monitoring and Control of Viruses in Food Supply Chains”










Agenda














Opening ceremony-what is expected

Hour 1st Day Afternoon

RegistrationOpening ceremony

(Raspor Peter, SI; Cook Nigel, UK)17:30-18:15 Plenary lecture:

The impact of food-borne viruses on human health in food supply chains

18:15-19:00 Plenary lecture:Consumers understanding of food-borne

viruses










Opening ceremony-who can answer?Plenary lecture: The impact of food-borne viruses on human health in food supply chains

Vinje Jan, USATitle: Foodborne viruses Author(s): Koopmans M, von Bonsdorff CH, Vinje J, et al.Source: FEMS MICROBIOLOGY REVIEWS Published: JUN 2002 Times Cited: 85

Title: Noroviruses: A comprehensive review Author(s): Patel MM, Hall AJ, Vinje J, et al.Source: JOURNAL OF CLINICAL VIROLOGY Published: JAN 2009 Times Cited: 13

Title: Norovirus Illness Is a Global Problem: Emergence and Spread of Norovirus GII.4 Variants, 2001-2007 Author(s): Siebenga JJ, Vennema H, Zheng DP, et al.Source: JOURNAL OF INFECTIOUS DISEASES Published: SEP 1 2009 Times Cited: 3









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Opening ceremony-who can answer?

Plenary lecture: Consumers understanding of food-borne viruses

Hulebak Karen (USA)- Chair of the Codex Alimentarius Commission or

Havelar Aria (NL)- Member of EFSA´s Panel on Biological Hazards

Title: Hazard Analysis and Critical Control Point (HACCP) history and conceptual overview Author(s): Hulebak KL, Schlosser WSource: RISK ANALYSIS Published: JUN 2002 Times Cited: 22

Title: Risk-based standards for Campylobacter in the broiler meat chain Author(s): Nauta MJ, Havelaar AH Source: FOOD CONTROL Published: APR 2008 Times Cited: 9









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Agenda














1st Session: Viruses in food supply chains- what is expected

Hour8:30-10:15

2nd Day

Chairs: Chris Michiels (BE), Luc Peeters (BE)

30 min Keynote speech: Future perspectives in food chain analysis (Carl Henrik von Bonsdorff, FL)

20 min Food safety issues in fresh produce production (Tamas Petrovic, RS)

20 min Food safety issues in animal origin produce (Ivo Pavlik, CZ)

20 min Codex Alimetarius principles for virus management (de Boer, NL)

15 min General Discussion / questions










1st Session: Viruses in food supply chains- who can answer

Keynote speech: Future perspectives in food chain analysis

Carl Henrik von Bonsdorff, FL

Title: Detection Of Human Norovirus From Frozen Raspberries In A Cluster Of Gastroenteritis Outbreaks Author(s): Maunula L, Roivainen M, Keranen M, et al.Source: EUROSURVEILLANCE Published: DEC 10 2009 Times Cited: 0

Title: Analysis of integrated virological and epidemiological reports of norovirus outbreaks collected within the Foodborne Viruses in Europe Network from 1 July 2001 to 30 June 2006 Author(s): Kroneman A, Verhoef L, Harris J, et al.Source: JOURNAL OF CLINICAL MICROBIOLOGY Published: SEP 2008 Times Cited: 12









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Agenda














2nd Session: Virus detection methods- what is expected

Hour:10:45-12:30

2nd Day

Chairs: Flemming Hansen (DK), Malcom Banks(UK)

30 min Keynote speech: Challenges in virus detection (Podgornik Aleš, SI)

20 min Concepts of methods development: in vivo vs. in vitro (Rosina Girones, ES)

20 min SOP as methodological tool in virus detection (David Rodriguez-Lazaro, ES)

20 min Robustness of VITAL methods (Martin D´Agostino, UK)











2nd Session: Virus detection methods-who can answer

Keynote speech: Challenges in virus detection Podgornik Aleš, SI

Title: Fast and efficient separation of immunoglobulin M from immunoglobulin G using short monolithic columns Author(s): Brne P, Podgornik A, Bencina K, et al.Source: JOURNAL OF CHROMATOGRAPHY A Published: MAR 9 2007 Times Cited: 11













AgendaGeneral informationStructure of the meetingOpening ceremony1st Session: Viruses in food supply chains2nd Session: Virus detection methods3rd Session: Monitoring of viruses in food supply chains4th Session: Risk assessment of viruses in food supply


chains”Workshop “Taking forward new development in monitoring

and control of viruses in food supply chains” Financial structure










3rd Session: Monitoring of viruses in food supply chains- what is expected

Hour16:00-17:30

2nd Day

Chairs: Clive Thompson (UK), Ivan Psikal (CZ)

30 min Keynote Speech: Challenges in Virus Monitoring (Franco Ruggeri, IT)

20 min Detection of viruses in primary production (Wim van der Poel, NL)

20 min Detection of viruses in food processing (Leena Maunula, FL)

20 min Detection of Viruses at point of sale (Artur Rzezutka, PL)










3rd Session: Monitoring of viruses in food supply chains-who can answer

Keynote Speech: Challenges in Virus Monitoring Franco Ruggeri, IT

Title: Massive outbreak of viral gastroenteritis associated with consumption of municipal drinking water in a European capital city Author(s): Werber D, Lausevic D, Mugosa B, et al.Source: EPIDEMIOLOGY AND INFECTION Published: DEC 2009 Times Cited: 0

Title: Waterborne outbreak of Norwalk-like virus gastroenteritis at a tourist resort, Italy Author(s): Boccia D, Tozzi AE, Cotter B, et al.Source: EMERGING INFECTIOUS DISEASES Published: JUN 2002 Times Cited: 48










VITAL Guidance manuals

Hour:17:30-18:00

2nd Day

Presentation of VITAL Guidance Manuals (Peter Raspor, Sl)























4th Session: Risk assessment of viruses in food supply chains- what is expected

Hour: 8:30-10:15

3rd Day

Chairs: Sava Lazic (RS), Jan Vinje (USA) Version A

30 min Keynote speech: Challenges in risk assessment in Europe (Aria Havelaar, NL)

20 min Principles of viral risk analysis (Dario De Medici, IT)

20 min Qualitative viral risk analysis (case HACCP) (Rita Moloney, IE)

20 min Development and validation of the VITAL Code of Good Practice for the food industry (Mateja Ambrozic, SI)












Hour: 8:30-10:15

3rd Day

Chairs: Sava Lazic (RS), Jan Vinje (USA) Version B

30 min Keynote speech: Challenges in risk assessment in Europe (Aria Havelaar, NL)

20 min Risk assessment of viruses in primary production

20 min Risk assessment of viruses in processing20 min Risk assessment of viruses at point of sale15 min General Discussion / questions










4th Session: Risk assessment of viruses in food supply chains-who can answer

Keynote speech: Challenges in risk assessment in Europe

Aria Havelaar, NL

Title: A risk assessment model for Campylobacter in broiler meat Author(s): Nauta MJ, Jacobs-Reitsma WF, Havelaar AH Source: RISK ANALYSIS Published: AUG 2007Times Cited: 19

Title: EFSA's 12th Scientific Colloquium - Assessing health benefits of controlling Campylobacter in the food chain Author(s): Bronzwaer S, Hugas M, Collins JD, et al.Source: INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY Published: MAY 31 2009 Times Cited: 0











Hour: 10:45-12:30

3rd Day

Chairs: Sava Lazic (RS), Jan Vinje (USA) 20 min A Modular Risk Process Model for Foodborne

Viruses (Saskia Rutjes, NL)20 min Data gap analysis for foodborne virus risk

assessment (Ana Maria de Roda Husman, NL)

20 min New tools for data analysis (Martijn Bouwknegt, NL)

45 min Speeches selected from abstracts























5th Session: Foodborne viruses control- what is expected

Hour13:45 – 15:30

3rd Day

Chairs: Peter Wyn Jones (UK), Carl-Henrik von Bonsdorff (FL)

30 min Keynote speech: Challenges in food borne viruses elimination (Nina Chanishvili, GE)

20 min Vaccination of pigs against HEV (Jeannete van der Goot, NL )

15 min Survival and elimination of adenovirus as an indicator (Anna Carratala)

15 min Survival and elimination of norovirus (Katherina Verhaelen)

15 min Survival and elimination of hepatitis E virus (Alessandra Berto)











5th Session: Foodborne viruses control-who can answer

Keynote speech: Challenges in food borne viruses elimination

Nina Chanishvili, GE

Title: Digitized fluorescent RFLP analysis (fRFLP) as a universal method for comparing genomes of culturable dsDNA viruses: application to bacteriophages Author(s): Merabishvili M, Verhelst R, Glonti T, et al.Source: RESEARCH IN MICROBIOLOGY Published: SEP 2007 Times Cited: 4

Title: Differential scanning calorimetry and hydrodynamic study of bacterial viruses. Effect of solution conditions Author(s): Mrevlishvili GM, Sottomayor MJ, Ribeiro da Silva MAV, et al.Source: JOURNAL OF THERMAL ANALYSIS AND CALORIMETRY Published: 2001 Times Cited: 4










5th Session: Foodborne viruses control- what is expected

Hour16:00 – 17:30

3rd Day

Chairs: Peter Wyn Jones (UK), Carl-Henrik von Bonsdorff (FL)Speeches selected from abstracts










VITAL Women in science prize

Hour17:30 – 18:00

3rd Day

Presentation of the VITAL Women in Science prize (Marta Hernandez, ES)VITAL Women in Science Prize Lecture (winner)























Training course: Control of viruses in food supply chains

This one-day course will focus on the integrated management systems which VITAL will recommend to the food industry. The course will be targeted towards risk managers, and provide information about virus hazards, and appropriate HACCP.

The course should begin with a 30 minute general presentation on food-borne viruses, but the rest of the content must be decided by Professors Raspor and Willems.










Training course: Control of viruses in food supply chains- what is

expectedHour 3rd Day

Chairs: Peter Raspor, (SI),Apostolos Vantarakis (GR)8:30-10:1530 min

20 min

20 min

20 min

15 min

European food industry: How much it suffer from microbial/viral contamination? (ie a. Luc Peeters, BE; b. Tatajana Zagorc, SI; Chamber of commerce)

Review of relevant food and water viruses (Sava Lazic, RS)

Critical review of critical control points for food contamination with viruses (Kris Willems, BE)

Methods for virus prevention and elimination (Marta Hernandez, ES)

General Discussion / questions










Training course: Control of viruses in food supply chains- what is

expectedHour 3rd Day

Chairs: Peter Raspor, (SI),Apostolos Vantarakis (GR)10:45- 12:30 Management principles arising from VITAL

Guidance Manuals (Peter Raspor, SI)13:45-15:30 Case study in groups (max. ? people in

group):animal food supply chains (animal food supply chains data gathering teams- i.e. Ivo Pavlik/ Franco Ruggeri/ David Rodriguez-Lazaro teams) plant food supply chains (plant food supply chains data gathering teams- i.e. Tamas Petrovic/ Artur Rzezutka/ Apostolos Vantarakis/ Ivo Pavlik/ Leena Maunula teams)

16:00-17:30 Reporting of working in groups and discussion























Training course: Monitoring of viruses in food supply chains

This one-day course will be organized for training analysts who were not part of VITAL, in the principles of integrated monitoring and risk analysis which VITAL will formulate. Participants will be trained how to implement monitoring if and when it is necessary, and also in the way they can transfer this knowledge to colleagues in their countries. This course can therefore be seen as a “training the trainers” course, and will play an important role in disseminating VITAL’s outcomes.

MorningCourse should begin with an overview of the COGP, to show the situations where monitoring will be necessary, and how to identify the sources and routes of contamination.Then a section concerning the actual monitoring of the identified critical points will follow. This should include a demonstration (video?) of the sampling and detection methods,. This section could be delivered by 2 – 3 people from the data-gathering laboratories.AfternoonThis should take the form of a training course in the VITAL data analysis tools, using examples from the project. This course could be delivered by RIVM team.










Training course: Monitoring of viruses in food supply chains- what is expected

Hour 3rd Day

Chairs: Kris Willems, BE; Ana Maria de Roda Husman, NL

8:30-10:15 Overview of Guidance Manuals (Mateja Ambrozic, SI)Definition of food supply chains with introduction to critical control points based on results of project VITAL (Rita Moloney, IE)Risk Assessment (Jack Schijven, NL)










Training course: Monitoring of viruses in food supply chains- what is expected

Hour 3rd Day10:45-12:30

Review of current methods for virus detection (David Rodriguez-Lazaro, ES) Monitoring of identified critical points (data gathering teams)

13:45-15:30

VITAL data analysis tools (RIVM team)

16:00-17:30

Reporting of working in groups and discussion























Workshop: Taking Forward New Developments in

Monitoring and Control of Viruses in Food Supply Chains

This workshop will be an excellent opportunity for interested parties, especially regulators, representatives of national and international bodies (e.g. EFSA, WHO, WTO), and members of the food industry, to discuss how the outcomes of VITAL will be integrated into food safety practices and regulations. Also invitations will be sent to scientific officers in Ministries of Food and Agriculture of all European countries. The aim of the workshop is to bring closer the scientists (virologists) with officials as well as industries in order to discuss the outcomes of the project and the role of viruses in food quality and public health. A specific section within the workshop will be devoted to regulatory issues.











Monitoring and Control of Viruses in Food Supply Chains-what is expected

Hour 4th Day

Chairs: Nigel Cook (UK), Peter Raspor (SI) 9:00-10:00 Registration 10:00-10:15 Relevance of the VITAL project for efficient

virus management in food supply chain by Nigel Cook UK

10:15-10:45 The view of EFSA on monitoring and control of viruses in food supply chains by Catherine Geslain-Lanéelle or by John Daniel Collins, Chair of Biological hazards












Hour 4th DayChairs: Nigel Cook (UK), Peter Raspor (SI)

10:45-11:15 The view of Codex Alimentarius Commission on monitoring and control of viruses in food supply chains by SI representative Blaža Nahtigal, or by Dr Emilio ESTEBAN chair FAO/WHO committee CODEX COMMITTEE ON FOOD HYGIENE

11:15-11:45 The view of FDA on monitoring and control of viruses in food supply chainschains by Camille E. Brewer, Office of the Commissioner office of foods, Center for Food Safety and Applied Nutrition, International Affairs Staff

11:45-12:45 Lunch













12:45-13:05 Outcomes of the VITAL project for efficient virus management in food supply chain: case production (Wim van der Poel)

13:05-13:25 Outcomes of the VITAL project for efficient virus management in food supply chain: case processing (Leena Maunula)

13:25-13:45 Outcomes of the VITAL project for efficient virus management in food supply chain: case point of sale (Artur Rzezutka)

13:45-14:05 Outcomes of the VITAL project for efficient virus management in food supply chain: case data analysis (Ana-Maria de Roda Husman)













14:05-14:25 Outcomes of the VITAL project for efficient virus management in food supply chain: case control measures (Kris Willems)

14:25-14:45 Outcomes of the VITAL project for efficient virus management in food supply chain: case delivering impact (Apostolos Vantarakis)

14:45-15:15 Break 14:45-16:00 Discussion: Should viruses be included in food

safety regulations? (moderators: Peter Raspor, Nigel Cook)

16:00 Closing of the Workshop.










Summary of lecturers by countryCountry No of lecturersUK 6FL 2IT 2USA 2NL 8BE 3IE 1SL 5CZ 2PL 1ES 4RS 2DK 1























Vital Symposium:New developments in monitoring and control of

viruses in food supply chains WHERE?

Ljubljana (Cankarjev dom) WHEN?

6. 6. 2011-9. 6. 2011










Financial structure

From proforma invoice for 300 persons: Place with all tehnical facility : 20.000€ + VAT Registration: 6.500€ + VAT Organization of the meeting by the CD agency: 10.000€ +

VAT Total: aprox. 45.000€

Our budget planned in WP’s for Symposium ?










Financial structure

Agreement in CD is in processing Registration fee for 4 days: 400€ Early registration 350 € Registration fee for event/day: 150€ Early registration 100€Special registration fee for VITAL members?










Steps

Organising and programme committee 1.may 2010

Agreement with CD signed 15.may 2010 Congress website 1.june 2010 Invitation to potential audience 1.june 2010 Draft programme 15. June 2010










Organising committee i.e.:

Peter Raspor, chair Mateja Ambrožič Nigel Cook, Leena Maunula Wim van der Poel Ana-Maria de Roda Husman Artur Rzezutka Apostolos Vantarakis Kris Willems










Thanks/Hvala!CONTACTS:Professor Dr. Peter Raspor, DDr.H.C.Head of Chair of Biotechnology, Microbiology and Food Safety

Mateja AmbrožičChair of Biotechnology, Microbiology and Food Safety

Biotechnical Faculty, University of LjubljanaJamnikarjeva 1011001 LJUBLJANASLOVENIJA

Tel.: +386 (0)1 423 11 61Fax: +386 (0)1 256 57 82

http://www.bf.uni-lj.si/zivilstvo/o-oddelku/katedre-in-druge-org-enote/za-biotehnologijo-mikrobiologijo-in-varnost-zivil.html









Documents

VITAL 3rd Annual Consortium Meeting National Veterinary Research Institute, Pulawy, Poland