· Web viewAttending Endocrinologist, & Jackson-Madison County General Hospital, Jackson, TN-July 2013-April 2015. PRACTICE/PROFESSIONAL EXPERIENCE July 2005 - June 2007 Endocrinology-

Ebenezer A. Nyenwe, MD

April 25, 2016 CURRICULUM VITAE

NAME: Ebenezer A. Nyenwe, MD, FWACP,FACP, FACE EDUCATION:

Undergraduate: College of Health Sciences, University of Port Harcourt, Nigeria. September 1982 - August 1989. Bachelor of Medicine, Bachelor of Surgery (MB, BS), August 1989. Bachelor of Medical Science (B Med Sc) Human Anatomy, August 1986 Graduate/Professional School: Residency and Fellowship in Internal Medicine Department of Medicine

University of Port Harcourt Teaching Hospital, Port Harcourt, Nigeria. September 1993 - April 2001. Fellow West African College of Physicians (FWACP), April 2001. Internship: Rotational University of Port Harcourt Teaching Hospital, Port Harcourt, Nigeria. September 1989 - September 1990 Residency:

Internal Medicine Department of Medicine Bronx-Lebanon Hospital Center Bronx, New York. July 2002 - June 2005 Postgraduate Training: Fellowship in Endocrinology Division of Endocrinology, Diabetes, and Metabolism, University of Tennessee Health Science Center Memphis, Tennessee. July 2005-June 2007

HONORS/AWARDS:

Undergraduate: 1. Dean’s Honor Roll, University of Port Harcourt, Nigeria. September 1982 –

August 1989 2. Best Graduating Student in Anatomy, University of Port Harcourt, Nigeria

August 1986

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Postgraduate:1. American Federation for Medical Research / Southern Society for Clinical

Investigation Trainee Award. March, 2006. 2. National Institute of Health / National Medical Association Travel Grant

Award. March, 2006. 3. American Federation for Medical Research / Southern Society for Clinical

Investigation Trainee Award. February, 2007. 4. America’s Top Physicians 2010. 5. Top Cited Research Paper Award 2011 by Metabolism: Clinical and

Experimental, published by Elsevier 6. American Federation for Medical Research / Southern Society for Clinical

Investigation Young Faculty Research Award 2012 7. Listed in Marquis Who’s Who in America 2012 8. Featured Doctor, Memphis Magazine, July 2012 9. America’s Top Physicians 2014

BOARD CERTIFICATION:

1. Diplomate of American Board of Internal Medicine in the specialty of Internal Medicine, August 2005.

2. Diplomate of American Board of Internal Medicine in the subspecialty of Endocrinology, Diabetes and Metabolism, October 2007.

LICENSURE:

MedicineTennessee Board of Medicine, No. 42527, July 2007, Active

SOCIETY MEMBERSHIPS:

Fellow of the American College of Physicians.Fellow of the American College of Endocrinology

Alpha Omega Alpha (AΩA) Honor Medical SocietyAmerican Diabetes Association.The Endocrine Society

National Medical Association. American Federation for Medical Research

CURRENT APPOINTMENT: May 2015- Date Associate Professor of Medicine

Division of Endocrinology, Diabetes and Metabolism, University of Tennessee Health Science Center, Memphis, Tennessee.

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PAST APPOINTMENTS:

July 2013-May 2015. Endocrinologist, The Jackson Clinic

July 2012- June 2013 Associate Professor of Medicine

Associate Director, Fellowship Training Program, Division of Endocrinology, Diabetes and Metabolism, University of Tennessee Health Science Center, Memphis, Tennessee.

January 2012 – June 2013Director

Section of Endocrinology & MetabolismRegional Medical Center, Memphis, Tennessee

2007 - 2012

Assistant Professor of Medicine Assistant Director, Fellowship Training Program, Division of Endocrinology, Diabetes and Metabolism, University of Tennessee Health Science Center, Memphis, Tennessee.

HOSPITAL/CLINICAL APPOINTMENTS:

Attending Endocrinologist, Methodist University Hospital, Memphis, Tennessee- May 2015-Date

Attending Endocrinologist, Regional Medical Center, Memphis, Tennessee-August 2007-June 2013

Attending Endocrinologist, UT Medical Group, Memphis, Tennessee-August 2007-June 2013

Attending Endocrinologist, & Jackson-Madison County General Hospital, Jackson, TN-July 2013-April 2015.

PRACTICE/PROFESSIONAL EXPERIENCE

July 2005 - June 2007 Endocrinology- Clinical and Research. Responsibilities include running endocrine clinics and consultations, carrying out procedures such as thyroid ultrasound and fine needle aspiration biopsies, as well as presentations at academic meetings.

July 2002 - June 2005

Internal Medicine and Primary Care- Inpatient and Ambulatory care including Intensive and Coronary care and Emergency medicine.

September 1993 - June 2002

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Registrar/Senior Registrar in Internal Medicine: University Teaching Hospital, Port Harcourt, Nigeria. Job description: Inpatient and Outpatient care, teaching of Junior Residents and Medical Students, participation in research and other educational activities.

January 1992 - August 1993

Senior House Officer, University Teaching Hospital, Sokoto, Nigeria

October 1990 - October 1991 Medical Officer. Specialist Hospital; Sokoto, Nigeria (National Service)

September 1989 – September 1990 Rotational Internship through Internal Medicine, Surgery, Pediatrics, Obstetrics and Gynecology University Teaching Hospital, Port Harcourt, Nigeria.

TEACHING EXPERIENCE:

1. September 1993- June 2007. Teaching of Medical Students and Residents as part of training in Internal Medicine and Endocrinology.

2. 2007-2013. Lectures, tutorials and clinical rounds for Medical Students, Residents and Endocrinology Fellows; University of Tennessee Health Science Center.

3. 2007-2013. Pathophysiology of thyroid disorders in Endocrinology Module for second year Medical Students, University of Tennessee Health Science Center.

4. 2008-2013. Introduction to Clinical Thyroidology- Approach to a patient with thyroid disease for third year Medical Students, University of Tennessee Health Science Center.

5. 2015-Date. Pathophysiology lectures: Obesity & Appetite regulation Hypoglycemia

Endocrine hypertension

6. 2015-Date. Capstone lectures for M4 students: Management of type 2 diabetes

VISITING PROFESSORSHIPS AND INVITED LECTURES:

1. October 2009- Memphis, Bluff City Medical Society: Principles and practice of insulin therapy in type 2 diabetes

2. March 2011- Medicine Grand Rounds, Department of Medicine, UTHSC: The evolution of diabetic ketoacidosis.

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3. April 2012- Presentation to Look AHEAD Study participants: Newer diabetes medications

4. March 2013- Presentation to Look AHEAD Study Participants. Sick day management for patients with diabetes.

5. May 2013- American Association of Clinical Endocrinologists: Endocrine and metabolic complications of HIV disease.

6. November 2013- Tennessee Academy of Nutrition and Dietetics: Newer diabetes medications: a focus on Incretins and SGLT-2 Inhibitors

7. March 2016- Medicine Grand Rounds, UTHSC: Tele-Endocrinology: bridging the gap in endocrine care via videoconferencing.

8. July 2016- National Medical Association: Approach to combination therapy in type 2 diabetes.

9. August 2016- Methodist Le Bonheur Healthcare: Optimal patient-oriented diabetes management in primary care.

Grand Rounds, Division of Endocrinology, UTHSC

1. Diabetic ketoacidosis in a city hospital. June 20062. Vasopressin and its antagonists in human disease. June 20073. Vasopressin antagonists (aquaretics) in human disease. April 20084. Metabolic syndrome & hepatic steatosis in hypopituitarism. December 20085. Metabolic Phenotype in Hypopituitarism: role of leptin. February 20106. Exploring The pre-nosology of diabetes: a preview of the POP-NMD Study

April 20117. Ethnic disparities in diabetes: a pursuit of its genesis. November 2011 8. Body composition, glucoregulation & energy expenditure in African-

Americans & Caucasians. January 20129. Tele-Endocrinology: bridging the gap in endocrine care via telemedicine.

November 201210. Vasopressin in human disease: an update. September 201511. Hepatic steatosis in hypopituitarism: effect of growth hormone. January 201612. An enquiry into the disparate prevalence of type 2 diabetes. August 2016

EDITORIAL APPOINTMENTS:

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Editorial Consultant for diabetic ketoacidosis, Smart Medicine. American College of Physicians.

Editorial Consultant for Type 1 diabetes, Smart Medicine. American College of Physicians.

Member, Editorial Board, Journal of Diabetes Research and Clinical Metabolism (JDRCM)

COMMITTEES AND OFFICES HELD:

Member, LooK AHEAD study writing group on “Changes in lean tissue mass composition after a weight loss intervention in adults with type 2 diabetes”

Reviewer for -The Journal of Clinical Endocrinology & Metabolism British Medical Journal Journal of Diabetes Hormone and Metabolic Research

The American Journal for the Medical Sciences Annals of Internal Medicine Archives of Internal Medicine BMJ Open Ad Hoc Grant Reviewer for the American Diabetes Association Faculty Advisory Committee, Department of Medicine Subspecialty Program Directors Committee, Department of Medicine Intern Selection Committee, Department of Medicine Clinic Improvement Committee, Department of Medicine Volunteer Service, Methodist Hospitals, Memphis, Tennessee

FELLOWS/GRADUATE STUDENTS TRAINED:

Fellows in Endocrinology1. Javeria Ahmad, MD; 2007-20082. Swaroopa Bartakke, MD; 2007-20083. Amna Khan, MD; 2007-20094. Dorota Malinowski, MD; 2007-20095. Malini Gupta-Ganguli, MD; 2008-20106. Omid Rad Pour, MD; 2009-20117. Dwaine Woode, MD; 2009-20118. Amanda Long, DO; 2010-20129. Nduche Onyeaso, MD; 2011-201310. Rabia Rehman, MD; 2011-201311. Bijan Ahrari, MD 2012

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12. Omodele Awoniyi, MD 201213. Crystal Jacovino, MD 201214. DeAnna Henderson, MD 2015-201615. Juliet Sandifer Kum-Nji, MD 2015-2016

Research Mentoring1. Sarah Bardoff BS- Medical Student NIH Research Fellowship Program, Summer

2006 2. Caroline Mbongo- RUST College Student Research Program, Summer 2008 3. Cherechi Ogwo BS- Medical Student NIH Research Fellowship Program,

Summer 2010 4. Britney Montgomery- RUST College Student Research Program, Summer 2010 5. Jaleesa Wright- Lemyne Owen College Student Research Program, Summer 2010

RESEARCH AND OTHER EXTERNAL SUPPORT:

1. R073316618 Kitabchi (PI), E Nyenwe (Co-investigator) 7/30/07-7/2/08Sanofi-Aventis

GlucommanderComparative Trial Between Computer-Guided Intravenous Infusion Protocol (Glucommander) Versus a Standard Insulin Infusion Algorithm in the ICU.

2. R073204043 10/1/07-9/30/09 Tennessee Department of Health Addressing Diabetes in Tennessee (ADT) E Nyenwe (co-investigator)

ADT aims to evaluate the efficacy of Telemedicine-based diabetes management program in improving quality of care and outcome in diabetic patients living in rural areas of Tennessee.

3. Clinical Trial of a Pharmaceutical Product E Nyenwe (PI) 01/13/10-10/30/2010 Thiazolidinedione Intervention with vitamin D Evaluation (TIDE) A multicenter randomized double-blind placebo-controlled trial of a thiazolidinedione (TZD) or placebo and of Vitamin D or placebo in people with type 2 diabetes at risk for cardiovascular disease.

4. R01 DK 067269 S Dagogo-Jack (PI), E Nyenwe (Co-investigator) 2006-2012 NIH/NIDDK Pathobiology of prediabetes in a bi-racial cohort (POP-ABC)

POP-ABC is an NIH-funded study designed to elucidate the predictors of progression from normoglycemia to prediabetes in African-Americans and Caucasians at high risk for type 2 diabetes.

5. Kitabchi (PI), E Nyenwe (Co-investigator) 7/1/09-6/31/12American Diabetes Association (ADA) Clinical Research Grant

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Effect of moderately high protein and low carbohydrate diet versus ADA diet on weight change and metabolic parameters in premenopausal women.

6. 3R01DK067269-04S1 S Dagogo-Jack (PI) 09/01/09-08/31/2011 NIH/NIDDK E Nyenwe (Co-investigator)

Normative Metabolic Data for the Pathobiology of Prediabetes (NMD-POP) studyNMD POP is an NIH funded study aimed at establishing normative metabolic parameters in subjects with no family history of diabetes. This would provide “normal” values that will be compared with the values obtained from matched subjects with parental history of diabetes in the prediabetes study cohort (see POP ABC study above).

7. U01-DK57078 Karen Johnson (PI), Abbas Kitabchi (Co-PI) 9/30/06-9/29/2013 NIH/NIDDK E Nyenwe (Co-investigator).

Look AHEAD (Action for Health in Diabetes) Look AHEAD is an NIH-sponsored, multi-center study developed to examine the long-term cardiovascular effects of an intervention program designed to achieve and maintain weight loss, compared with standard intervention, in overweight volunteers with type 2 diabetes

8. Clinical Trial of a Pharmaceutical Product. E Nyenwe (PI). The Effect of Delaglutide (LY2189265) on major cardiovascular events in patients with type 2 diabetes: Reducing Cardiovascular Events with a Weekly INcretin in Diabetes (REWIND). This is a phase 3, multicenter, randomized, double-blind, placebo-controlled, parallel study to assess the effects of LY2189265 on cardiovascular outcomes in patients with type 2 diabetes who are drug naïve or who are on a stable antidiabetic regimen.

9. Clinical Trial of a Pharmaceutical Product. S Dagogo-Jack (PI), E Nyenwe (Co-investigator) Liraglutide Effect and Action in Diabetes (LEADER): Evaluation of cardiovascular outcome results, a long-term, multi-center, international, randomized double-blind, placebo-controlled trial to determine liraglutide effects on cardiovascular events

10. Clinical Trial of a Pharmaceutical Product. S Dagogo-Jack (PI), E Nyenwe (Co-investigator) Saxagliptin Assessment of Vascular Outcomes Recorded in Patients with Diabetes Mellitus (SAVOR). A multicenter, randomized, double-blind, placebo-controlled phase IV trial to evaluate the effect of saxagliptin on the incidence of cardiovascular death, myocardial infarction or ischemic stroke in patients with type 2 diabetes

11. Clinical Trial of a Pharmaceutical Product. S Dagogo-Jack (PI), E Nyenwe (Co-investigator)

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A multicenter, international, randomized, parallel group, double blind study to evaluate Cardiovascular safety of Linagliptin versus glimepiride in patients with type 2 diabtes mellitus at high cardiovascular risk. The CAROLINA Trial.

12. S Dagogo-Jack (PI), Nyenwe EA (Co-investigator): Development of genotyping assay for identifying prediabetes risk.

13. Kitabchi (PI), E Nyenwe (Co-investigator) 7/1/12-6/31/15American Diabetes Association (ADA) Clinical Research Grant Effect of moderately high protein and low carbohydrate diet versus high carbohydrate diet on weight change and metabolic parameters in subjects with prediabetes.

Research Skills

1. Hyperinsulinemic euglycemic clamp, Intravenous Glucose Tolerance Test (IVGTT), and Oral Glucose Tolerance Test (OGTT).

2. Techniques in metabolic research: Determination of Resting Energy Expenditure (REE) using indirect calorimetry and body composition using DXA scan.

3. Clinical trials design and execution

BOOK AND BOOK CHAPTERS:

1. Nyenwe EA, Dagogo-Jack S. Diabetes mellitus in high-risk ethnic populations in Goldstein BJ, Mueller-Wieland D (Eds) Type 2 diabetes: principles and practice, 2nd

edition, 2008; Chapter 33 501-512. Taylor & Francis Group, New York.

2. Nyenwe EA, Dagogo-Jack S. Endocrinopathies in HIV disease in Mullen M, Caplivsky D (Editors). HIV and Co-morbidities: A case-based approach to diagnosis and management. 2008; Chapter 11; 171-185. Oxford University Press, New York.

3. Kitabchi AE, Nyenwe EA. Hyperglycemic crisis in adult patients with diabetes mellitus. In Wass JA, Shalet SM, Amiel SA (editors). Oxford Textbook of Endocrinology and Diabetes, 2nd edition. New York: Oxford University Press. 2011

PEER-REVIEWED JOURNAL ARTICLES:

1. Didia BC, Nyenwe EA. Foot Breadth in children – its relationship to limb dominance and age. Foot and Ankle 1988; 8: 198-202.

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2. Stanley P, Nyenwe E, Ihekwaba A. Schizophrenia-like psychosis in a Sickler. The Nigerian Health Journal 2000; (3/4): 121-122.

3. Nyenwe EA, Odia OJ, Ihekwaba AE, Ojule A, Babatunde S. Type 2 diabetes in adult Nigerians: a study of its prevalence and risk factors in Port Harcourt, Nigeria. Diabetes Research and Clinical Practice 2003; 62: 177-185.

4. Kitabchi AE, Nyenwe EA. Hyperglycemic crises in diabetes mellitus: diabetic ketoacidosis and hyperglycemic hyperosmolar state. Endocrinol and Metab Clin North Am. 2006; 35:725-51.

5. Ihekwaba AE, Nyenwe EA. Aetiological considerations of 96 consecutive cases of ascites. Port Harcourt Medical Journal 2006; 1:29-33.

6. Kitabchi AE, Nyenwe EA. Sliding scale regular insulin: more evidence needed before final exit. Diabetes Care 2007; 30:2409-10.

7. Nyenwe EA, Loganathan R, Blum S, Ezuteh D, Erani D, Palace M, Ogugua C. Admissions for diabetic ketoacidosis in ethnic minority groups in a city hospital. Metabolism 2007; 56:172-178.

8. Nyenwe EA, Loganathan R, Blum S, Ezuteh D, Erani D, Wan JY, Palace MR, Kitabchi AE. Active use of cocaine: an independent risk factor for recurrent diabetic ketoacidosis in a city hospital. Endocr Pract. 2007; 13:22-29.

10 Nyenwe EA, Dagogo-Jack S. Recognition of Iodine Deficiency Disorders in the Iodine-Replete Environment. N Engl J. Med. 2007; 357: 1263-4.

11 Nyenwe, EA, Fisher JN. A Mistaken Diagnosis of Type 2 Diabetes Due To Hemoglobin N-Baltimore. Am J Med Sci. 2008; 336:524-526.

12 Nyenwe EA, Fisher JN, VanMiddlesworth L. Lithium therapy: an unusual cause of elevated and diffuse radioactive iodine uptake. J Radiology Case Reports. 2008; 2:1-4.

13 Nyenwe EA, Dagogo-Jack S. Iodine Deficiency Disorders in the Iodine-Replete Environment. Am J Med Sci. 2009; 337:37-40.

13. Nyenwe EA, Williason-Badorff S, Waters B, Wan JY, Solomon SS. Non-alcoholic fatty liver disease and metabolic syndrome in hypopituitary patients. Am J Med Sci. 2009; 338:190-195.

14. Nyenwe EA, Razavi LN, Kitabchi AE, Khan AN, Wan JY. Acidosis: The prime determinant of depressed consciousness in diabetic ketoacidosis. Diabetes Care. 2010; 33:1837-9.

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15. Look AHEAD Research Group, Wing RR. Long-term effects of a lifestyle intervention on weight and cardiovascular risk factors in individuals with type 2 diabetes mellitus: four-year results of the Look AHEAD trial. Arch Intern Med. 2010; 170:1566-75.

16. Nyenwe EA, Jerkins TW, Umpierrez GE, Kitabchi AE. Management of Type 2 Diabetes: Evolving strategies for the treatment of type 2 diabetes. Metabolism. 2011; 60:1-23.

17. Nyenwe EA, Ashby S, Tidwell J, Nouer SS, Kitabchi AE. Improving diabetes care via telemedicine. Lessons from the Addressing Diabetes in Tennessee (ADT) Project. Diabetes Care. 2011; 34:e1 (DOI: 10.2337/dc10-2260)

18. Dagogo-Jack S, Edeoga C, Nyenwe E, Chapp-Jumbo E, Wan J. Pathobiology Of Prediabetes in a Biracial Cohort (POP-ABC) Design and Methods. Ethnicity & Disease. 2011; 21:33-39

19. Nyenwe EA, Dagogo-Jack S. Metabolic syndrome, prediabetes and the science of primary prevention. Minerva Endocrinol. 2011; 36:129-45.

20. Nyenwe E. Intensive insulin therapy in hospitalised patients increases the risk of hypoglycaemia and has no effect on mortality, infection risk or length of stay. Evid Based Med. 2011; 94:340-51.

21. Nyenwe EA, Kitabchi AE. Evidence-based management of hyperglycemic emergencies in diabetes mellitus. Diabetes Research & Clinical Practice. 2011; 94:340-51

22. Wadden TA, Neiberg RH, Wing RR, Clark JM, Delahanty LM, Hill JO, Krakoff J, Otto A, Ryan DH, Vitolins MZ; Look AHEAD Research Group. Four-year weight losses in the Look AHEAD study: factors associated with long-term success. Obesity (Silver Spring). 2011; 19:1987-98.

23. The TIDE Trial Investigators. Design, history and results of the Thiazolidinedione Intervention with vitamin D Evaluation (TIDE) randomized controlled trial. Diabetologia. 2012; 55:36-45.

24. Brancati FL, Evans M, Furberg CD, Geller N, Haffner S, Kahn SE, Kaufmann PG, Lewis CE, Nathan DM, Pitt B, Safford MM; Look AHEAD Study Group. Midcourse correction to a clinical trial when the event rate is underestimated: the Look AHEAD (Action for Health in Diabetes) Study. Clin Trials. 2012; 9:113-24.

25. Rejeski WJ, Ip EH, Bertoni AG, Bray GA, Evans G, Gregg EW, Zhang Q; Look AHEAD Research Group. Lifestyle change and mobility in obese adults with type 2 diabetes. N Engl J Med. 2012; 366:1209-17.

26. Chapp-Jumbo E, Edeoga C, Wan J, Dagogo-Jack S; Pathobiology of Prediabetes in a Biracial Cohort (POP-ABC) Research Group. Ethnic disparity in hemoglobin A1c levels among normoglycemic offspring of parents with type 2 diabetes mellitus. Endocr Pract. 2012;18:356-62.

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27. Kitabchi AE, McDaniel KA, Wan JY, Tylavsky FA, Jacovino CA, Sands CW, Nyenwe EA, Stenz FB. Effects of High-Protein Versus High-Carbohydrate Diets on Markers of b-Cell Function, Oxidative Stress, Lipid Peroxidation, Proinflammatory Cytokines, and Adipokines in Obese, Premenopausal WomenWithout Diabetes. Diabetes Care. 2013; 36:1919-25.

28. Dagogo-Jack S, Edeoga C, Ebenibo S, Chapp-Jumbo E; Pathobiology of Prediabetes in a Biracial Cohort (POP-ABC) Research Group. Pathobiology of Prediabetes in a Biracial Cohort (POP-ABC) study: baseline characteristics of enrolled subjects. J Clin Endocrinol Metab. 2013;98:120-8

29. Unick JL, Beavers D, Bond DS, Clark JM, Jakicic JM, Kitabchi AE, Knowler WC, Wadden TA, Wagenknecht LE, Wing RR; Look AHEAD Research Group. The long-term effectiveness of a lifestyle intervention in severely obese individuals. Am J Med. 2013; 1263:236-42.

30. Look AHEAD Research Group, Wing RR, Bolin P, Brancati FL, Bray GA, et al. Cardiovascular effects of intensive lifestyle intervention in type 2 diabetes. N Engl J Med. 2013; 369:145-54.

31. Nyenwe EA, Wan JY, Kitabchi AE. Venous Serum Bicarbonate Concentration Predicts Arterial pH In Adults with Diabetic Ketoacidosis. Endocr Pract 2014; 20(3):201-6

32. McCaffery JM, Papandonatos GD, Huggins GS, Peter I, et al. Genetic Subgroup of Look AHEAD; Look AHEAD Research Group. Human cardiovascular disease IBC chip-wide association with weight loss and weight regain in the look AHEAD trial. Hum Hered. 2013;75(2-4):160-74.

33. Dagogo-Jack S, Edeoga C, Ebenibo S, Nyenwe E, Wan J; for the Pathobiology of Prediabetes in a Biracial Cohort (POP-ABC) Research Group. Lack of Racial Disparity in Incident Prediabetes and Glycemic Progression among Black and White Offspring of Parents with Type 2 Diabetes: The Pathobiology of Prediabetes in a Biracial Cohort (POP-ABC) Study. J Clin Endocrinol Metab. 2014;99(6):E1078-87

34. Espeland MA, Lewis CE, Bahnson J, Knowler WC, Regensteiner JG, Gaussoin SA, Beavers D, Johnson KC; Look AHEAD Research Group. Impact of weight loss on ankle-brachial index and interartery blood pressures. Obesity (Silver Spring). 2014; 22(4):1032-41.

35. Ebenibo S, Edeoga C, Ammons A, Egbuonu N, Dagogo-Jack S; Pathobiology of Prediabetes in a Biracial Cohort (POP-ABC) Research Group. Recruitment strategies and

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yields for the Pathobiology of Prediabetes in a Biracial Cohort: a prospective natural history study of incident dysglycemia. BMC Med Res Methodol. 2013;13:64.

36. Espeland MA, Glick HA, Bertoni A, Brancati FL, Bray GA, Clark JM, Curtis JM, Egan C, Evans M, Foreyt JP, Ghazarian S, GreggEW, Hazuda MP, Hill JO, Hire D, Horton ES, Hubbard VS, Jakicic JM, Jeffery RW, Johnson KC, Kahn SE, Killean T, Kitabchi AE, Knowler WC, Kriska A, Lewis CE, Miller M, Montez MG, Anne Murillo A, Nathan MD, Nyenwe E, Patricio J, Peters A, Pi-Sunyer X, Pownall H, Redmon B, Rushing J, Ryan DH, Safford M, Tsai AG, Wadden TA,Wing RR, Yanovski SZ, Zhang P. Look AHEAD Research Group. Impact of an Intensive Lifestyle Intervention on Use and Cost of Medical Services among Overweight and Obese Adults with Type 2 Diabetes: The Action for Health in Diabetes. Diabetes Care, 2014; 37(9):2548-56.

37. Espeland MA, Rapp SR, Bray GA, Houston DK, Johnson KC, Kitabchi AE, Hergenroeder AL, Williamson J, Jakicic JM, van Dorsten B, Kritchevsky SB; Action for Health In Diabetes (Look AHEAD) Movement and Memory Subgroup; Look AHEAD Research Group. Long-term impact of behavioral weight loss intervention on cognitive function. J Gerontol A Biol Sci Med Sci. 2014; 69(9):1101-8.

38. William C. Knowler WC, Bahnson JL, Bantle JP, Bertoni AG, Bray GA, Chen H, Cheskin L, Clark JM, Egan C, Evans M, Foreyt JP, Glasser S, Greenway FL, Gregg EW, Hazuda HP, Hill JO, Horton ES, Hubbard VS, Jakicic JM, Jeffery RW, Johnson KC, Kahn SE, Kitabchi AE, Korytkowski M, Krakoff J, Lewis CE, Maschak-Carey BJ, Michaels S, Montez MG, Murillo A, Nathan DM, Nyenwe E, Patricio J, Peters A, Pi-Sunyer X, Pownall H, Wadden TA, Wagenknecht LE, Williamson DF, Wing RR, Wyatt H, Yanovski SZ. The Look AHEAD Research Group. Effect of a Long-Term Behavioral Weight Loss Intervention on Nephropathy in Overweight or Obese Adults with Type 2 Diabetes: the Look AHEAD Randomized Clinical Trial. The Lancet Diabetes & Endocrinology. 2014; 2 (10):801-809

39. Pownall HJ, Bray GA, Wagenknecht LE, Walkup MP, Heshka S, Hubbard VS, Kahn SE, Nathan DM, Schwarts AV, Johnson KC; Look AHEAD Research Group. Changes in body composition over 8 years in a randomized trial of a lifestyle intervention: the look AHEAD study. Obesity (Silver Spring). 2015; 23 (3):565-72

40. Unick JL, Neiberg RH, Hogan PE, Cheskin LJ, Dutton GR, Jeffery R, Nelson JA, Pi-Sunyer X, West DS, Wing RR; Look AHEAD Research Group. Weight change in the first 2 months of a lifestyle intervention predicts weight changes 8 years later. Obesity (Silver Spring). 2015 Jul;23(7):1353-6.

41. McCaffery JM, Anderson A, Bantle JP, Berkowitz RI, Bray GA, Cheskin L, Clark JM, Curtis JM, Delahanty LM, Evans M; Foreyt JP, Glasser S, Gregg EW, Hanson RL, Hazuda HP, Hill JO, Horton ES, Huggins GS, Jakicic JM, Jeffery RW, Johnson KC,

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Kahn SE, Kelley DE, Kitabchi AE, Knowler KC, Lewis CE, Montez MG, Anne Murillo A, David M. Nathan DM, Nyenwe E,; Pajewski NM, Papandonatos GD, Patricio J, Peter I, Peters A, Pi-Sunyer X, Henry Pownall H, Thomas A. Wadden TA, Wagenknecht LE, Wing RR, Wyatt H, The Look AHEAD Research Group. Prospective association of a genetic risk score and lifestyle intervention with cardiovascular morbidity and mortality among individuals with type 2 diabetes: the Look AHEAD randomized controlled trial. Diabetologia. 2015 Aug;58(8):1803-13.

42. Espeland MA, Probstfield J, Hire D, Redmon JB, Evans GW, Coday M, Lewis CE, Johnson KC, Wilmoth S, Bahnson J, Dulin MF, Green JB, Knowler WC, Kitabchi A, Murillo AL, Osei K, Rehman SU, Cushman WC; Look AHEAD Research Group; ACCORD Study Group. Systolic Blood Pressure Control Among Individuals With Type 2 Diabetes: A Comparative Effectiveness Analysis of Three Interventions. Am J Hypertens. 2015 Aug;28(8):995-1009.

43. Rehman RA, Nicole Pant N, Tidwell JW, Ashby SJ, Nyenwe EA. Tele-Endocrinology: providing endocrine consultative service using telemedicine Tennessee Medicine E-Journal. 2015; Vol. 1: Iss. 3, Article 6.

44. Nyenwe EA, Kitabchi AE. The Evolution of diabetic ketoacidosis: An update of its etiology, pathogenesis and management. Metabolism. 2016; 65:507-21.

45. Marso SP, Daniels GH, Brown-Frandsen K, Kristensen P, Mann JF, Nauck MA, Nissen SE, Pocock S, Poulter NR, Ravn LS, Steinberg WM, Stockner M, Zinman B, Bergenstal RM, Buse JB; LEADER Steering Committee; LEADER Trial Investigators. Liraglutide and Cardiovascular Outcomes in Type 2 Diabetes. N Engl J Med. 2016; 375(4):311-22.

46. Gallagher D, Kelley DE, Thornton J, Boxt L, F. Pi-Sunyer X, Lipkin E, Goldman V, Isaiah Janumala I, Heshka S, Look AHEAD Research Group. Changes in Skeletal Muscle and Organ Size after a Weight Loss Intervention in Overweight and Obese Type 2 Diabetic Patients. Am J Clin Nutr (in review)

OTHER PUBLICATIONS:

Abstracts:

1. Nyenwe, EA, Osuala TC. Awareness and effectiveness of oral rehydration therapy in a Nigerian rural population- community based study. (Abstract No. 46). In: Proceedings of the 22nd Annual Conference of the Pediatric Association of Nigeria, January 1991.

2. Stanley P, Nyenwe E. A 26 year old sickler with acute psychosis: case report presented at the International Conference on Sickle Cell Disease and Environmental Sickling Agents, Nigeria, August, 2000.

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3. Nyenwe EA, Loganathan RS, Blum S, Ezuteh DO, Erani D, Palace MR, Ogugua Characteristics of patients admitted with diabetic ketoacidosis in an inner city hospital. Journal of Investigative Medicine, 2006; 54: (suppl. 1) S 267.

4. Nyenwe EA, Loganathan RS, Blum S, Ezuteh DO, Erani, DM Jim Y. Wan JY, Palace MR, Kitabchi AE. Substance abuse and hospital admissions for diabetic ketoacidosis. Diabetes. 2006; 55(suppl 1):A233.

5. Nyenwe EA, Bartakke, S, Mack EA, Fisher JN. Hemoglobin N Baltimore: another cause of false HbA1c estimation. Journal of Investigative Medicine, 2007; 55 (suppl. 1):S296.

6. Nyenwe EA, Dagogo-Jack S. Recognition of iodine deficiency disorders in the iodine-replete environment. Journal of Investigative Medicine, 2007; 55 (suppl. 1):S297.

7. Nyenwe EA, Mack EA, Dagogo-Jack S. Resurgent iodine deficiency disorders in the iodine abundant environment. Abstract P4-368. Proceedings of the 89th Annual Meeting of The Endocrine Society June 2007: 761.

8. Nyenwe EA, Fisher JN, VanMiddlesworth L. Lithium therapy: an unusual cause of elevated and diffuse radioactive iodine uptake. Thyroid, 2007; 17(suppl 1): S-83.

9. Williamson-Baddorf S, Nyenwe E, Waters B, Solomon SS. Nonalcoholic fatty liver disease and metabolic syndrome in hypopituitary patients. Journal of Investigative Medicine, 2008; 56(1):461.

10. Khan AN, Nyenwe EA, Williams-Cleaves B. Osteoporotic fracture in a young woman treated with medroxyprogesterone acetate. Journal of Investigative Medicine, 2008; 56(1):384-385.

11. Razavi L, Nyenwe E, Khan A, Ahmed J, Bartakke R, Zaidi S, Radpour O, Kitabchi A. Determinants of mental status in adults presenting with diabetic ketoacidosis. Journal of Investigative Medicine, 2009; 57:397.

12. Nyenwe EA, Gray S, Nouer S. Improving Diabetes Care and Outcome via Telemedicine: Preliminary Data from Addressing Diabetes in Tennessee (ADT) Project. Journal of Diabetes Science and Technology, 2009; 3:384-387, A122.

13. Nyenwe E, Khan A, Razavi L, Long A, Ahmed J, Bartakke R, Gupta-Ganguli M, Wan J, Kitabchi A. Acidosis: An independent Determinant of altered sensorium in diabetic ketoacidosis. Diabetes. 2009; Suppl (1):A121

14. Nyenwe E, Gray S, Mbongo C, Nouer S, A Kitabchi A. Telemedicine in diabetes care: lessons from the Addressing Diabetes in Tennessee (ADT) project. Journal of Investigative Medicine, 2010; 58: 449.

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15. Goldberg R, Jihad Arteh J, Nyenwe E. Syphilitic proctitis in a young man. Journal of Investigative Medicine, 2010; 58:406.

16. Nyenwe E, Ashby SG, Nouer S. ADT: The impact and significance of a Telehealth-based diabetes management program in rural Tennessee. Telemedicine & E-Health. 2010; 16(suppl 1)104

17. Woode DE, Givens C, Nyenwe E. Thyroid Sarcoidosis: A case report. American Association of Clinical Endocrinologists 2010 Scientific Sessions, Abstract # 1052, page 176.

18. Kitabchi AE, Hutson ML, Tylavsky FA, Stentz FB, Wan JY, Nyenwe EA, Sands CW. Effect of high protein or high carbohydrate diet on markers of oxidative stress and proinflammatory cytokines in obese non-diabetic premenopausal women. American Diabetes Association (ADA) 2010 Scientific Sessions; June 25-29, 2010, Orlando, Florida

19. Ogwo C, Nyenwe E, Edeoga C, Chapp-Jumbo E, Dagogo-Jack S. Glucoregulation in normoglycemic offspring of diabetic or non-diabetic parents. Journal of Investigative Medicine. 2011; 59:413

20. Nyenwe E, Edeoga C, Ogwo C, Chapp-Jumbo E, Dagogo-Jack S. Cardiometabolic risk factors in normoglycemic offspring of diabetic or non-diabetic parents. Journal of Investigative Medicine. 2011, 59:413

21. Haddad M, Stentz FB, Kitabchi AE, Nyenwe EA, Tylavsky F, Wan J, McDaniel K, Sands C. Comparison of high protein and high carbohydrate diets on levels of inflammation in obese pre-menopausal women. Journal of Investigative Medicine. 2011; 59:511

22. Littleton T, Stentz FB, Kitabchi AE, Nyenwe EA, Tylavsky F, Wan J, McDaniel K, Sands C. Effect of diet composition on weight change and metabolic parameters in obese premenopausal women. Journal of Investigative Medicine. 2011; 59:412

23. Jacovino CA, Stentz FB, Kitabchi AE, McDaniel K, Tylavsky F, Nyenwe E, Wan J, Sands C. Effect of diet composition on renal function in obese non-diabetic premenppausal women Journal of Investigative Medicine 2011: 59:412

24. Nyenwe E, Edeoga C, Chapp-Jumbo E, Wan J, Dagogo-Jack S. Age as a modifier of β-Cell response to Insulin resistance among normoglycemic African American and Caucasian offspring of parents with or without diabetes. Diabetes 2011; (Suppl 1): A680

25. Nyenwe E, Edeoga C, Ogwo C, Chapp-Jumbo E, Dagogo-Jack S. Preponderance of cardiometabolic risk factors is determined by obesity, but not parental history of diabetes in normoglycemic subjects. American Association of Clinical Endocrinologists 2011 Scientific Sessions Abstract Number 225.

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26. Edeoga C, Chapp-Jumbo E, Nyenwe E, Wan J, Dagogo-Jack S. Gender dimorphism in augmentation of HDL cholesterol levels in healthy persons with premicroalbuminuria. Endocrine Society. 93rd Annual Scientific Meetings, Boston, MA, June 2011.

27. Chapp-Jumbo E, Edeoga C, Nyenwe E, Dagogo-Jack S. Insulin Action and Secretion in a Biracial Cohort with Low-Normal, High-Normal or Impaired Fasting Glucose. Endocrine Society. 93rd Annual Scientific Meetings, Boston, MA, June 2011.

28. Edeoga C, Chapp-Jumbo E, Egbuonu N, Nyenwe E, Dagogo-Jack S. Parental history of type 2 diabetes abrogates ethnic disparity in insulin sensitivity. Diabetes 2011; 60(Suppl 1): A423

29. Edeoga C, Chapp-Jumbo E, Ammons A, Nyenwe E, Dagogo-Jack S. Pathobiology Of Prediabetes in a Biracial Cohort (POP-ABC): interim report on early progressors. Diabetes 2011; 60(Suppl 1): A375

30. Tylavsky F, Kitabchi AE, Stentz FB, McDaniel K, Nyenwe EA, Wan J, Sands C. Effect of high-protein and high-carbohydrate weight reduction diets on bone density and body composition in obese non-diabetic, pre-menopausal women. Diabetes 2011; 60(Suppl 1): A511

31. Kitabchi AE, Stentz FB, McDaniel KA, Hutson M, Wan JY, Tylavsky F, Nyenwe EA, Sands CW. Effect of high-protein and high-carbohydrate diets on insulin resistance, oxidative stress, and lipid peroxidation in obese, non-diabetic, premenopausal women. Diabetes 2011; 60(Suppl 1): A462

32. Kitabchi AE, Stentz FB, Nyenwe EA, McDaniel K, Tylavsky F, Wan J, Sands C. Effect of dietary macronutrients on oxidative stress, cardiovascular risk factors, and insulin sensitivity in obese, non-diabetic, premenopausal women. 47th EASD Annual Meeting, Lisbon, Portugal; September 2011

33. Nyenwe E, Edeoga C, Ebenibo S, Chapp-Jumbo E, Wan J, Dagogo-Jack S. Body composition, glucoregulation and energy expenditure in healthy African-Americans and Caucasians. Journal of Investigative Medicine 2012; 60:348

34. Long A, Jiang Y, Gosmanov A, Nyenwe E. Recurrent primary hyperparathyroidism in a 61 year old woman. Journal of Investigative Medicine 2012; 60:347

35. Rehman R, Nyenwe E. Papillary thyroid carcinoma in a toxic nodule. Journal of Investigative Medicine 2012; 60:350-351

36. Rehman R, Pant N, Ashby S, Tidwell J, Nyenwe E. Tele-endocrinology: bridging the gap in endocrine care via tele-medicine. American Association of Clinical Endocrinologists 2012 Scientific Sessions

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37. Nyenwe E, Wan J, Kitabchi A. Venous serum bicarbonate level predicts arterial pH in adults with diabetic ketoacidosis. Diabetes 2012; 61 (Suppl 1) A242

38. Wheeler D, Stentz FB, Kitabchi AE, McDaniel K A, Tylavsky FA, Wan JY, Nyenwe EA, Jacovino C, Sands CW. Effect of diet composition on metabolic parameters. Journal of Investigative Medicine 2012; 60:352

39. Kitabchi AE, Stentz FB, Nyenwe EA, McDaniel K A, Tylavsky FA, Wan JY, Sands CW. Effect of macronutrients on markers of oxidative stress, proinflammatory cytokines, adipokines, cardiovascular risk factors and lipid peroxidation in obese non-diabetic women. Diabetes 2012; 61 (Suppl 1): A11

40. Edeoga C, Ebenibo S, Wan J, Nyenwe E, Dagogo-Jack S. Pathobiology of Prediabetes in a Biracial Cohort (POP -ABC) Study: Baseline Characteristics and Glycemic Outcomes During 5.5 Years of Follow-Up. Diabetes 2012; 61 (Suppl 1A): 68-LB

41. Stenz FB, Kitabchi AE, McDaniel K, Nyenwe EA, Tylavsky FA, Wan JY, Sands CW. Effect of High Protein vs. High Carbohydrate Diets on Incretins in Obese, Nondiabetic, Premenopausal Women. Diabetes 2012; 61 (Suppl 1A): 101-LB

42. Jacovino CA, Stentz FB, Kitabchi AE, McDaniels K, Tylavsky F, Nyenwe E, Wan J, Sands C. Effect of diet composition on HDL and urinary microalbuminu in obese non-metabolic syndrome females. Journal of Investigative Medicine. 2013; 61:399

43. Awoniyi O, Nyenwe E. Predictors of resolution in patients with diabetic ketoacidosis: serum bicarbonate vs anion gap. Journal of Investigative Medicine 2013; 61: 496

44. Jacovino C, Nyenwe E, Dagogo-Jack S. Assessment of Fine Needle Aspiration sampling of thyroid biopsies in an academic center with early adoption of bedside evaluation by cytology. American Association of Clinical Endocrinologists 2013 Scientific Sessions

45. Brannick B; Nyenwe E. Gynecomastia in a Man Treated with Clomiphene. Journal of Investigative Medicine 2016; 64:528-529. doi:10.1136/jim-2015-000035

46. Brannick B, Paschall V, Nyenwe, E. Gynecomastia in a Man Treated with Clomiphene citrate. Research in Medicine & Alpha Omega Alpha Research Day presentation, Poster # 4 February, 2016.

Dissertations:

1. Nyenwe, EA. Limb Dominance and foot breadth in children. B.Med.Sc degree in Human Anatomy, of the University of Port Harcourt, Nigeria; 1986.

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2. Nyenwe EA. Awareness and effectiveness of oral rehydration therapy as a treatment for acute childhood diarrhea in a Nigerian rural population. MB BS degree of the University of Port Harcourt; Nigeria; 1989.

3. Nyenwe EA. Prevalence of Type 2 Diabetes amongst adults in Port Harcourt, Nigeria. West African Postgraduate Medical College Fellowship (FWACP) in Internal Medicine. April 2001.

Other Non-Peer Reviewed Works:

1. Adedayo O, Nyenwe E, Gabrielli M. Paracetamol toxicity following therapeutic dosage- a case report submitted to the Department of Medicine, Bronx Lebanon Hospital Center. May 2003.

2. Nyenwe EA. Characteristics of patients admitted with diabetic ketoacidosis in Bronx Lebanon Hospital Center. June 2005.

3. Nyenwe E. How to prevent diabetes and its complications. Women’s Journal, Jackson Tennessee, April/May 2014.

OTHER PROFESSIONAL ACTIVITIES/TRAINING:

1. 16th National training course on drug addiction, organized by the International Council on Alcohol and Addiction and the University of Benin, Nigeria. October 1996.

2. Workshop on research methodology, organized by the National Postgraduate Medical College of Nigeria in collaboration with SmithKline Beecham (Nigeria) Plc and West African Postgraduate Medical College, September 1998.

3. African Malaria Vaccine Testing Network (AMVTN) and SmithKline Beecham International workshop on Good Clinical Practice (GCP) and Clinical Trials Methodology, held in Bagamoyo, Tanzania, February 2000.

4. National Institutes of Health / National Medical Association seminar on career in academic medicine, August 2006.

5. Endocrine Fellows Foundation training program on diabetes, April 2006.

6. Diabetes Freedom Foundation and Endocrine Fellows Foundation training course on Diabetes, September 2006.

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7. Endocrine University: Technology for Endocrinology Fellows-in-Training, organized by American College of Endocrinology and Mayo Clinic, March 2007.

COMMUNITY SERVICE:

1. Provision of endocrinology consultation services to rural communities in the state of Tennessee with remote access to specialized endocrine care. This service was provided utilizing telemedicine facilities at the University of Tennessee Health Science.

2. Diabetes self-management education to rural communities in Tennessee was also been provided with above facilities. These programs have been well received by the communities.

3. Participation in Health Fairs in the community to deliver talks on diabetes prevention and self-management.

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Documents

· Web viewAttending Endocrinologist, & Jackson-Madison County General Hospital, Jackson, TN-July 2013-April 2015. PRACTICE/PROFESSIONAL EXPERIENCE July 2005 - June 2007 Endocrinology-