UCLA Medical Center Santa Monica

UCLAOrthopaedic Hospital Department of Orthopaedic Surgery

Alumni Bulletin 2013

2

A Message from Department Chair Jeffrey J Eckardt MD

Welcome to the 2013 AAOS UCLAOH Alumni Reception Irsquom glad to report that over the past several years wersquove had many accomplishments and 2012 was a banner year in many ways We moved into our new facility at the UCLA Medical Center Santa Monica opened an eight-unit outpatient surgery center across the street and opened the UCLA Spine Center on Wilshire Boulevard and 16th Street in Santa Monica Our residents continue to perform well on their Orthopaedic Surgery In-Training Examinations and Irsquove been very pleased with their fellowship opportunities after graduation We are expanding our basic skills laboratory for all residents to include sawbones cadaver dissections as well as OR matrices all mandated by the ACGME and Irsquom delighted that former resident Nicholas Bernthal MD is joining our faculty after fellowship this summer We now have a total of 73 clinical and research faculty members in the Department Our alliance with the Los Angeles Orthopaedic Hospital and the development of the Orthopaedic Hospital Research Center has strengthened our research efforts exponentially We are now ranked 7

in the nation for National Institutes of Health (NIH) funding among all University programs for orthopaedic research and look forward to increasing those efforts We have also been gearing up and are about to implement UCLArsquos electronic medical record system CareConnect which has been a huge undertaking and wersquore grateful for all those who have helped We have started a new section in this bulletin with news of several of our Alumni and would ask that you in the future send us pictures and news of how yoursquore doing including honors awards and exciting announcements It is my hope that you will all keep in touch and come to visit us if in Los Angeles Please help us strengthen our Alumni network by updating your contact information and donating to the residency or fellowship program andor Alumni Association wwworthouclaedualumni Sincerely yours Jeffrey J Eckardt MD Professor and Chair Department of Orthopaedic Surgery The Helga and Walter Oppenheimer Chair of Musculoskeletal Oncology 10833 Le Conte Avenue 76-143 CHS Los Angeles CA 90095-6902 Phone (310) 794-7930 Fax (310) 794-0021 jeckardtmednetuclaedu

3

A Message from LAOH President and CEO Anthony A Scaduto MD The alliance between UCLA and the Los Angeles Orthopaedic Hospital began in 1998 and creates a platform for unparalleled contributions to patient care and scientific discovery in orthopaedic surgery and musculoskeletal medicine We strive to be the destination for satisfied patients world-class faculty and inquisitive students by creating a new standard of musculoskeletal care for the 21st century 2011 was a big year for Orthopaedic Hospital We celebrated our 100-year anniversary and the opening of the new UCLA Medical Center Santa Monica The state-of-the-art facility was designed to enhance the entire orthopaedic service line We also opened outstanding new clinical and administrative facilities in the adjacent Orthopaedic Hospital Institute This unique alliance also benefits from integrated leadership As Chair of the Department Jeffrey Eckardt MD serves on the Board of Directors of Los Angeles Orthopaedic Hospital and the Executive Medical Board in Santa Monica I was recently named President and CEO of Los Angeles Orthopaedic Hospital and also serve as the Executive Vice Chair of the Department John Adams MD is the Vice Chair of Research and leads the Orthopaedic Hospital Research Center Our biomechanics research team lead by Harry McKellop PhD is moving into dedicated research space in Westwood and Santa Monica Orthopaedic Hospital and UCLA are true partners in pursuit of the same vision-- to achieve excellence in orthopaedic care research and education Sincerely Anthony A Scaduto MD Executive Vice Chair Department of Orthopaedic Surgery Division Chief and Charles LeRoy Lowman Professor of Pediatric Orthopaedics President and CEO Los Angeles Orthopaedic Hospital 2400 South Flower Street Los Angeles CA 90007 Phone (213) 742-1122 Fax (213) 7421435

tscadutomednetuclaedu

4

The UCLAOrthopaedic Hospital Department of Orthopaedic Surgery continues its mission of providing outstanding clinical care resident and fellow education and research at the basic science translational and clinical levels Our goal as a Department is to integrate clinical care education and research while maintaining the highest levels of patient satisfaction with cutting-edge surgical techniques

This location serves as the inpatient and outpatient hub of the UCLAOrthopaedic Hospital Department of Orthopaedic Surgery Constructed as part of the alliance between UCLA Orthopaedic Surgery and Los Angeles Orthopaedic Hospital this facility houses state-of-the-art operating suites inpatient facilities faculty offices and outpatient exam rooms

FACILITIES January 8 2012 marked the opening of the new UCLA Medical Center Santa Monica located on Wilshire and 16th Street in Santa Monica CA

The Santa Monica Ambulatory Surgery Center which opened in March 2012 is located directly

across from the hospital on 16th Street It features eight operating rooms and sixty percent of the cases previously done in the main hospital are now treated at this facility The UCLA Spine Center opened on July 30 2012 and houses our joint spine program with neurosurgery Our orthopaedic spine surgeons are Drs Jeffrey Wang Nick Shamie and Michael Daubs Our neurosurgery spine specialists are Drs Langston Holly Duncan McBride and Daniel Lu In

addition Drs David Fish and Jae Jung are

interventional pain

management specialists

providing non-operative care of spinal disorders Together these physicians form a nucleus to

provide expertise in treatment for our operative and non-operative management of spinal disorders Immediately upstairs from the Spine Clinic is one of the UCLA rehabilitation offices with state-of-the-art equipment and techniques to facilitate pre-and post-operative physical therapy for all of our patients The Los Angeles Orthopaedic Medical Center has added and updated facilities to continue to provide

5

world-class pediatric orthopaedic care both in the original downtown Los Angeles location and in Santa Monica Led by Anthony Scaduto MD President Chief Executive Officer and Lowman Professor of Pediatric Orthopaedics the Renee and Meyer Luskin Childrenrsquos Clinic moved into the new UCLA Medical Center Santa Monica and Orthopaedic Hospital in January 2012 This facility now serves as the westside focal point of Pediatric Orthopaedics at UCLA Also more than 55000 childrens orthopaedic visits are conducted at the 40000-square-foot Orthopaedic Hospital Outpatient Medical Center on the Downtown Los Angeles Orthopaedic Medical Center campus In addition we remain extremely proud of the Orthopaedic Hospital Medical Magnet High School Opened as an alliance with Los Angeles Unified School District this magnet high school emphasizes healthcare and medical science Ronald Reagan UCLA Medical Center which opened on June 29 2008 serves as the home of our Level I Orthopaedic Traumatology program headed by Drs Eric Johnson Devon Jeffcoat and Eric Farrell with the able assistance of multiple other faculty members

The Orthopaedic Hospital Research Center (OHRC) opened in 2007This state-of-the-art 3500-square-foot research facility is led by John Adams MD our Vice Chair of Research

The UCLAOrthopaedic Hospital Department of Orthopaedic Surgery also provides a diverse training experience and has strong affiliate relationships with Harbor-UCLA Medical Center Olive View-UCLA Medical Center Shriners Hospital for Children (pictured) and West Los Angeles Veterans Affairs Medical Center

3

A Message from LAOH President and CEO Anthony A Scaduto MD The alliance between UCLA and the Los Angeles Orthopaedic Hospital began in 1998 and creates a platform for unparalleled contributions to patient care and scientific discovery in orthopaedic surgery and musculoskeletal medicine We strive to be the destination for satisfied patients world-class faculty and inquisitive students by creating a new standard of musculoskeletal care for the 21st century 2011 was a big year for Orthopaedic Hospital We celebrated our 100-year anniversary and the opening of the new UCLA Medical Center Santa Monica The state-of-the-art facility was designed to enhance the entire orthopaedic service line We also opened outstanding new clinical and administrative facilities in the adjacent Orthopaedic Hospital Institute This unique alliance also benefits from integrated leadership As Chair of the Department Jeffrey Eckardt MD serves on the Board of Directors of Los Angeles Orthopaedic Hospital and the Executive Medical Board in Santa Monica I was recently named President and CEO of Los Angeles Orthopaedic Hospital and also serve as the Executive Vice Chair of the Department John Adams MD is the Vice Chair of Research and leads the Orthopaedic Hospital Research Center Our biomechanics research team lead by Harry McKellop PhD is moving into dedicated research space in Westwood and Santa Monica Orthopaedic Hospital and UCLA are true partners in pursuit of the same vision-- to achieve excellence in orthopaedic care research and education Sincerely Anthony A Scaduto MD Executive Vice Chair Department of Orthopaedic Surgery Division Chief and Charles LeRoy Lowman Professor of Pediatric Orthopaedics President and CEO Los Angeles Orthopaedic Hospital 2400 South Flower Street Los Angeles CA 90007 Phone (213) 742-1122 Fax (213) 7421435

tscadutomednetuclaedu

4

The UCLAOrthopaedic Hospital Department of Orthopaedic Surgery continues its mission of providing outstanding clinical care resident and fellow education and research at the basic science translational and clinical levels Our goal as a Department is to integrate clinical care education and research while maintaining the highest levels of patient satisfaction with cutting-edge surgical techniques

This location serves as the inpatient and outpatient hub of the UCLAOrthopaedic Hospital Department of Orthopaedic Surgery Constructed as part of the alliance between UCLA Orthopaedic Surgery and Los Angeles Orthopaedic Hospital this facility houses state-of-the-art operating suites inpatient facilities faculty offices and outpatient exam rooms

FACILITIES January 8 2012 marked the opening of the new UCLA Medical Center Santa Monica located on Wilshire and 16th Street in Santa Monica CA

The Santa Monica Ambulatory Surgery Center which opened in March 2012 is located directly

across from the hospital on 16th Street It features eight operating rooms and sixty percent of the cases previously done in the main hospital are now treated at this facility The UCLA Spine Center opened on July 30 2012 and houses our joint spine program with neurosurgery Our orthopaedic spine surgeons are Drs Jeffrey Wang Nick Shamie and Michael Daubs Our neurosurgery spine specialists are Drs Langston Holly Duncan McBride and Daniel Lu In

addition Drs David Fish and Jae Jung are

interventional pain

management specialists

providing non-operative care of spinal disorders Together these physicians form a nucleus to

provide expertise in treatment for our operative and non-operative management of spinal disorders Immediately upstairs from the Spine Clinic is one of the UCLA rehabilitation offices with state-of-the-art equipment and techniques to facilitate pre-and post-operative physical therapy for all of our patients The Los Angeles Orthopaedic Medical Center has added and updated facilities to continue to provide

5

world-class pediatric orthopaedic care both in the original downtown Los Angeles location and in Santa Monica Led by Anthony Scaduto MD President Chief Executive Officer and Lowman Professor of Pediatric Orthopaedics the Renee and Meyer Luskin Childrenrsquos Clinic moved into the new UCLA Medical Center Santa Monica and Orthopaedic Hospital in January 2012 This facility now serves as the westside focal point of Pediatric Orthopaedics at UCLA Also more than 55000 childrens orthopaedic visits are conducted at the 40000-square-foot Orthopaedic Hospital Outpatient Medical Center on the Downtown Los Angeles Orthopaedic Medical Center campus In addition we remain extremely proud of the Orthopaedic Hospital Medical Magnet High School Opened as an alliance with Los Angeles Unified School District this magnet high school emphasizes healthcare and medical science Ronald Reagan UCLA Medical Center which opened on June 29 2008 serves as the home of our Level I Orthopaedic Traumatology program headed by Drs Eric Johnson Devon Jeffcoat and Eric Farrell with the able assistance of multiple other faculty members

The Orthopaedic Hospital Research Center (OHRC) opened in 2007This state-of-the-art 3500-square-foot research facility is led by John Adams MD our Vice Chair of Research

The UCLAOrthopaedic Hospital Department of Orthopaedic Surgery also provides a diverse training experience and has strong affiliate relationships with Harbor-UCLA Medical Center Olive View-UCLA Medical Center Shriners Hospital for Children (pictured) and West Los Angeles Veterans Affairs Medical Center

4

The UCLAOrthopaedic Hospital Department of Orthopaedic Surgery continues its mission of providing outstanding clinical care resident and fellow education and research at the basic science translational and clinical levels Our goal as a Department is to integrate clinical care education and research while maintaining the highest levels of patient satisfaction with cutting-edge surgical techniques

This location serves as the inpatient and outpatient hub of the UCLAOrthopaedic Hospital Department of Orthopaedic Surgery Constructed as part of the alliance between UCLA Orthopaedic Surgery and Los Angeles Orthopaedic Hospital this facility houses state-of-the-art operating suites inpatient facilities faculty offices and outpatient exam rooms

FACILITIES January 8 2012 marked the opening of the new UCLA Medical Center Santa Monica located on Wilshire and 16th Street in Santa Monica CA

The Santa Monica Ambulatory Surgery Center which opened in March 2012 is located directly

across from the hospital on 16th Street It features eight operating rooms and sixty percent of the cases previously done in the main hospital are now treated at this facility The UCLA Spine Center opened on July 30 2012 and houses our joint spine program with neurosurgery Our orthopaedic spine surgeons are Drs Jeffrey Wang Nick Shamie and Michael Daubs Our neurosurgery spine specialists are Drs Langston Holly Duncan McBride and Daniel Lu In

addition Drs David Fish and Jae Jung are

interventional pain

management specialists

providing non-operative care of spinal disorders Together these physicians form a nucleus to

provide expertise in treatment for our operative and non-operative management of spinal disorders Immediately upstairs from the Spine Clinic is one of the UCLA rehabilitation offices with state-of-the-art equipment and techniques to facilitate pre-and post-operative physical therapy for all of our patients The Los Angeles Orthopaedic Medical Center has added and updated facilities to continue to provide

5

world-class pediatric orthopaedic care both in the original downtown Los Angeles location and in Santa Monica Led by Anthony Scaduto MD President Chief Executive Officer and Lowman Professor of Pediatric Orthopaedics the Renee and Meyer Luskin Childrenrsquos Clinic moved into the new UCLA Medical Center Santa Monica and Orthopaedic Hospital in January 2012 This facility now serves as the westside focal point of Pediatric Orthopaedics at UCLA Also more than 55000 childrens orthopaedic visits are conducted at the 40000-square-foot Orthopaedic Hospital Outpatient Medical Center on the Downtown Los Angeles Orthopaedic Medical Center campus In addition we remain extremely proud of the Orthopaedic Hospital Medical Magnet High School Opened as an alliance with Los Angeles Unified School District this magnet high school emphasizes healthcare and medical science Ronald Reagan UCLA Medical Center which opened on June 29 2008 serves as the home of our Level I Orthopaedic Traumatology program headed by Drs Eric Johnson Devon Jeffcoat and Eric Farrell with the able assistance of multiple other faculty members

The Orthopaedic Hospital Research Center (OHRC) opened in 2007This state-of-the-art 3500-square-foot research facility is led by John Adams MD our Vice Chair of Research

The UCLAOrthopaedic Hospital Department of Orthopaedic Surgery also provides a diverse training experience and has strong affiliate relationships with Harbor-UCLA Medical Center Olive View-UCLA Medical Center Shriners Hospital for Children (pictured) and West Los Angeles Veterans Affairs Medical Center

5

world-class pediatric orthopaedic care both in the original downtown Los Angeles location and in Santa Monica Led by Anthony Scaduto MD President Chief Executive Officer and Lowman Professor of Pediatric Orthopaedics the Renee and Meyer Luskin Childrenrsquos Clinic moved into the new UCLA Medical Center Santa Monica and Orthopaedic Hospital in January 2012 This facility now serves as the westside focal point of Pediatric Orthopaedics at UCLA Also more than 55000 childrens orthopaedic visits are conducted at the 40000-square-foot Orthopaedic Hospital Outpatient Medical Center on the Downtown Los Angeles Orthopaedic Medical Center campus In addition we remain extremely proud of the Orthopaedic Hospital Medical Magnet High School Opened as an alliance with Los Angeles Unified School District this magnet high school emphasizes healthcare and medical science Ronald Reagan UCLA Medical Center which opened on June 29 2008 serves as the home of our Level I Orthopaedic Traumatology program headed by Drs Eric Johnson Devon Jeffcoat and Eric Farrell with the able assistance of multiple other faculty members

The Orthopaedic Hospital Research Center (OHRC) opened in 2007This state-of-the-art 3500-square-foot research facility is led by John Adams MD our Vice Chair of Research

The UCLAOrthopaedic Hospital Department of Orthopaedic Surgery also provides a diverse training experience and has strong affiliate relationships with Harbor-UCLA Medical Center Olive View-UCLA Medical Center Shriners Hospital for Children (pictured) and West Los Angeles Veterans Affairs Medical Center

6

RESIDENTFELLOW EDUCATION UCLA continues to pride itself on training some of the finest orthopaedic surgery residents in the country Our goal is to train both outstanding clinicians and future academic leaders Each year we are faced with the difficult task of choosing from the best-qualified applicants in the country in an increasingly competitive field We are rewarded with bright young minds that provide outstanding care and strengthen our Department Led by Program Director James V Luck Jr MD Associate Program Director Nelson Soohoo MD and with the indispensable assistance of Medical Education Coordinator Connie Sams C-TAGME we currently train six residents per residency class In addition two residents per year choose to complete a prestigious one-year research fellowship between second and third years of residency Our 2012-2013 research residents are Trevor Scott MD and Alexandra Stavrakis MD

In addition to the Santa Monica and Ronald Reagan UCLA Medical Centers our residents continue to rotate at Harbor-UCLA Medical Center Shriners Hospital Los Angeles the West Los Angeles VA Hospital Olive View-UCLA Medical Center and the Downtown campus of the Los Angeles Orthopaedic Hospital Louis Kwong MD has taken over as Interim Chair of Harbor-UCLA Daniel Zinar MD has stepped down after many years of very able leadership In 2011 our residency program received a five-year accreditation (the longest duration of accreditation that can be received) without any citations This highest evaluation is only given to 3 of all

programs by the Residency Review Committee In addition to our residency program we have five excellent postgraduate fellowship programs Each year we train two fellows in Orthopaedic Sports Medicine two in Hand Surgery two in Spine Surgery one in Pediatric Orthopaedics and one in Physical Medicine and Rehabilitation These trainees have completed their orthopaedic surgery residencies and have chosen to spend one year at UCLA for subspecialty training In June 2012 we welcomed our new intern class

As we welcomed our interns we also said farewell to the graduating chief resident class of 2012 (pictured on next page left to right) They are now training at the following fellowship programs

Mark Elzik MD Hand Surgery Philadelphia Hand Center PA

Dan Le MD Joint Replacement New England Baptist Hospital Boston MA

Paul Celestre MD Spine Surgery Norton Leatherman Louisville KY

Tad Kremen MD Sports Medicine Duke University Durham NC

Nicholas Bernthal MD Orthopaedic Oncology Huntsman Cancer Institute Salt Lake City UT

Locky Chambers MD Sports Medicine Hospital for Special Surgery New York NY

Remi Ajiboye Obioma Amajoyi Edward Cheung MD UCSF MD UCLA MD Brown Univ

Erik Dworsky MD Christopher Lee Ankur Patel Case Western Reserve MD USC MD UCSD

7

The current chief residents (graduating in June 2013 and pictured below left to right) matched to the following fellowships Nikita Bezrukov MD Sports Medicine

Kaiser Permanente Orange County CA Bradley Aspey MD Sports Medicine

Andrews Institute for Orthopaedics amp Sports Medicine Pensacola FL

Jared Johnson MD Sports Medicine Steadman Philippon Research Institute Vail CO

Jeremy Reid MD Joint Replacement Hospital for Special Surgery New York NY

Roberto Diaz MD Hand Surgery Stanford University Hand amp Upper Limb Center

Palo Alto CA Alan Zhang MD Sports Medicine UCSF San Francisco CA

8

Since 2011 we have welcomed the following new faculty members to our Department Jae Jung MD (PMampR Pain Management)

Eric Farrell MD (Trauma Surgery)

Daniel Boguszewski PhD (Biomechanics)

Michael Daubs MD (SpineDeformity Surgery)

Susan Bukata MD (OncologyOsteoporosis)

Daniel Vigil MD (Sports MedicineNon-Operative)

The Division of Foot and Ankle Surgery was founded by Andrea Cracchiolo III MD (pictured)

in 1978 he remains on the faculty as Professor Emeritus The Division is now led by Nelson F SooHoo MD who cares for patients with reconstructive and traumatic conditions of the foot and ankle Dr SooHoo is actively involved in the American

Orthopaedic Foot and Ankle Society and currently serves on the managerial board of the AOFAS Orthopaedic Foot and Ankle Registry initiative Dr Cracchiolo is actively involved in medical student and resident education Lewis Zionts MD from Los Angeles Orthopaedic Hospital focuses on the conservative non-operative treatment of pediatric clubfoot deformity The primary objectives of the Division include providing patient-centered care and advancing the science of foot and ankle surgery

FOOT AND ANKLE SURGERY

The General Orthopaedics section was founded in 2010 by bringing three community orthopaedic surgeons together Peter G Alexakis MD Bruce A Brown MD PhD and S Andrew Schwartz MD Combined they see an average of 650 patient visits per month Dr Brown has a concomitant surgical practice at UCLA Medical Center Santa Monica and the VA involving joint replacement and trauma cases The service is dedicated to facilitating timely access to orthopaedic consultation treatment and referral to appropriate UCLA orthopaedic subspecialists

GENERAL ORTHOPAEDICS

Dr Jung joined us in April 2011 from the Universal Pain Management center in Palmdale CA He specializes in physical medicine amp rehabilitation and interventional pain management

Dr Farrell joined us in August 2011 from the University of Medicine and Dentistry of New Jersey He specializes in trauma surgery

Dr Boguszewski joined us in January 2012 from the University of Cincinnati He specializes in biomechanics research

Dr Daubs joined us in March 2012 from the University of Utah He specializes in spine and deformity surgeon in adults and children

Dr Bukata joined us in April 2012 from the University of Rochester She specializes in musculoskeletal oncology and osteoporosis

Dr Vigil joined us in March 2013 from Kaiser Los Angeles He specializes in sports medicine and non-operative orthopaedics

9

General orthopaedic referrals are seen at both the Westwood and Santa Monica facilities Urgent same-day consultations are accommodated by these three physicians

The UCLA hand surgery service founded by Roy Meals MD (pictured) in 1979 is nationally recognized as one of the most successful truly integrated orthopaedic and plastic surgery hand surgery programs in the country Dr Meals is a clinical professor of hand surgery with clinical areas of expertise in elbow surgery thumb basal joint arthritis and Dupuytrenrsquos disease He is the former president of the American Society for Surgery of the Hand and the editor-in-chief for the Journal of Hand Surgery The hand service provides the full spectrum of hand surgery including surgery for complex reconstructions tendon transfers trauma rheumatoid arthritis compression neuropathies congenital hand differences scleroderma elbow nerve injuries Dupuytrenrsquos contracture and tumors The UCLA hand service has performed the first hand transplantation in the Western United States under the direction of Dr Kodi Azari one of the most experienced reconstructive transplant surgeons The hand team covers UCLA Santa Monica-UCLA Wadsworth VA Olive View-UCLA and Los Angeles Shriners Medical Centers The hand fellowship continues to be one of the most highly ranked fellowships in the country with our graduating fellows universally reporting an excellent training experience

HAND SURGERY

Prosper Benhaim MD now the Division Chief of Hand Surgery at UCLA and Olive View-UCLA Medical Centers joined the Department in 1998 He has numerous local and national committee positions including an editorial position for the Journal of the American Society for Surgery of the

Hand Dr Benhaim has a national reputation as an educator and has been a leader in the treatment of Dupuytrenrsquos disease Kodi Azari MD came to UCLA from the University of Pittsburgh Medical Center in 2008 Dr Azari has been involved in both clinical and laboratory research for more than 18 years and is the author of numerous research articles book chapters and presentations He lectures extensively both nationally and internationally on hand surgery as well as plastic surgery Dr Azari is the surgical director of the newly established UCLA Hand Transplant Program In 2011 he led a team of Surgeons at Ronald Reagan UCLA Medical Center that performed the first hand transplant in the western United States in an operation that lasted 14-12 hours and concluded on Saturday March 5 The transplant was performed on a 26-year-old woman from northern California who lost her right hand in a traffic accident nearly five years before UCLA is only the fourth center in the nation to offer this procedure and the first west of the Rockies It was the 13th hand transplant surgery performed in the United States Dr Azari has been one of the lead surgeons on six hand transplantation operations including the first double hand transplantation and first arm transplantation performed in the United States (wwwhandtransplantuclaedu) Scott Mitchell MD is an Assistant Professor and former outstanding UCLA resident and fellow who joined the faculty in 2009 He performs complex hand wrist and elbow surgery at UCLA Santa Monica-UCLA Medical Center and the West Los Angeles Veterans Affairs Hospital Drs Benhaim Azari and Mitchell all completed their hand fellowships at UCLA

The joint replacement program was founded in 1971 by Harlan Amstutz MD (pictured on next page) who is now an emeritus faculty member and actively practices at St Vincent Medical Center Bert Thomas MD is now the Division Chief and

JOINT REPLACEMENT

7

The current chief residents (graduating in June 2013 and pictured below left to right) matched to the following fellowships Nikita Bezrukov MD Sports Medicine

Kaiser Permanente Orange County CA Bradley Aspey MD Sports Medicine

Andrews Institute for Orthopaedics amp Sports Medicine Pensacola FL

Jared Johnson MD Sports Medicine Steadman Philippon Research Institute Vail CO

Jeremy Reid MD Joint Replacement Hospital for Special Surgery New York NY

Roberto Diaz MD Hand Surgery Stanford University Hand amp Upper Limb Center

Palo Alto CA Alan Zhang MD Sports Medicine UCSF San Francisco CA

8

Since 2011 we have welcomed the following new faculty members to our Department Jae Jung MD (PMampR Pain Management)

Eric Farrell MD (Trauma Surgery)

Daniel Boguszewski PhD (Biomechanics)

Michael Daubs MD (SpineDeformity Surgery)

Susan Bukata MD (OncologyOsteoporosis)

Daniel Vigil MD (Sports MedicineNon-Operative)

The Division of Foot and Ankle Surgery was founded by Andrea Cracchiolo III MD (pictured)

in 1978 he remains on the faculty as Professor Emeritus The Division is now led by Nelson F SooHoo MD who cares for patients with reconstructive and traumatic conditions of the foot and ankle Dr SooHoo is actively involved in the American

Orthopaedic Foot and Ankle Society and currently serves on the managerial board of the AOFAS Orthopaedic Foot and Ankle Registry initiative Dr Cracchiolo is actively involved in medical student and resident education Lewis Zionts MD from Los Angeles Orthopaedic Hospital focuses on the conservative non-operative treatment of pediatric clubfoot deformity The primary objectives of the Division include providing patient-centered care and advancing the science of foot and ankle surgery

FOOT AND ANKLE SURGERY

The General Orthopaedics section was founded in 2010 by bringing three community orthopaedic surgeons together Peter G Alexakis MD Bruce A Brown MD PhD and S Andrew Schwartz MD Combined they see an average of 650 patient visits per month Dr Brown has a concomitant surgical practice at UCLA Medical Center Santa Monica and the VA involving joint replacement and trauma cases The service is dedicated to facilitating timely access to orthopaedic consultation treatment and referral to appropriate UCLA orthopaedic subspecialists

GENERAL ORTHOPAEDICS

Dr Jung joined us in April 2011 from the Universal Pain Management center in Palmdale CA He specializes in physical medicine amp rehabilitation and interventional pain management

Dr Farrell joined us in August 2011 from the University of Medicine and Dentistry of New Jersey He specializes in trauma surgery

Dr Boguszewski joined us in January 2012 from the University of Cincinnati He specializes in biomechanics research

Dr Daubs joined us in March 2012 from the University of Utah He specializes in spine and deformity surgeon in adults and children

Dr Bukata joined us in April 2012 from the University of Rochester She specializes in musculoskeletal oncology and osteoporosis

Dr Vigil joined us in March 2013 from Kaiser Los Angeles He specializes in sports medicine and non-operative orthopaedics

9

General orthopaedic referrals are seen at both the Westwood and Santa Monica facilities Urgent same-day consultations are accommodated by these three physicians

The UCLA hand surgery service founded by Roy Meals MD (pictured) in 1979 is nationally recognized as one of the most successful truly integrated orthopaedic and plastic surgery hand surgery programs in the country Dr Meals is a clinical professor of hand surgery with clinical areas of expertise in elbow surgery thumb basal joint arthritis and Dupuytrenrsquos disease He is the former president of the American Society for Surgery of the Hand and the editor-in-chief for the Journal of Hand Surgery The hand service provides the full spectrum of hand surgery including surgery for complex reconstructions tendon transfers trauma rheumatoid arthritis compression neuropathies congenital hand differences scleroderma elbow nerve injuries Dupuytrenrsquos contracture and tumors The UCLA hand service has performed the first hand transplantation in the Western United States under the direction of Dr Kodi Azari one of the most experienced reconstructive transplant surgeons The hand team covers UCLA Santa Monica-UCLA Wadsworth VA Olive View-UCLA and Los Angeles Shriners Medical Centers The hand fellowship continues to be one of the most highly ranked fellowships in the country with our graduating fellows universally reporting an excellent training experience

HAND SURGERY

Prosper Benhaim MD now the Division Chief of Hand Surgery at UCLA and Olive View-UCLA Medical Centers joined the Department in 1998 He has numerous local and national committee positions including an editorial position for the Journal of the American Society for Surgery of the

Hand Dr Benhaim has a national reputation as an educator and has been a leader in the treatment of Dupuytrenrsquos disease Kodi Azari MD came to UCLA from the University of Pittsburgh Medical Center in 2008 Dr Azari has been involved in both clinical and laboratory research for more than 18 years and is the author of numerous research articles book chapters and presentations He lectures extensively both nationally and internationally on hand surgery as well as plastic surgery Dr Azari is the surgical director of the newly established UCLA Hand Transplant Program In 2011 he led a team of Surgeons at Ronald Reagan UCLA Medical Center that performed the first hand transplant in the western United States in an operation that lasted 14-12 hours and concluded on Saturday March 5 The transplant was performed on a 26-year-old woman from northern California who lost her right hand in a traffic accident nearly five years before UCLA is only the fourth center in the nation to offer this procedure and the first west of the Rockies It was the 13th hand transplant surgery performed in the United States Dr Azari has been one of the lead surgeons on six hand transplantation operations including the first double hand transplantation and first arm transplantation performed in the United States (wwwhandtransplantuclaedu) Scott Mitchell MD is an Assistant Professor and former outstanding UCLA resident and fellow who joined the faculty in 2009 He performs complex hand wrist and elbow surgery at UCLA Santa Monica-UCLA Medical Center and the West Los Angeles Veterans Affairs Hospital Drs Benhaim Azari and Mitchell all completed their hand fellowships at UCLA

The joint replacement program was founded in 1971 by Harlan Amstutz MD (pictured on next page) who is now an emeritus faculty member and actively practices at St Vincent Medical Center Bert Thomas MD is now the Division Chief and

JOINT REPLACEMENT

8

Since 2011 we have welcomed the following new faculty members to our Department Jae Jung MD (PMampR Pain Management)

Eric Farrell MD (Trauma Surgery)

Daniel Boguszewski PhD (Biomechanics)

Michael Daubs MD (SpineDeformity Surgery)

Susan Bukata MD (OncologyOsteoporosis)

Daniel Vigil MD (Sports MedicineNon-Operative)

The Division of Foot and Ankle Surgery was founded by Andrea Cracchiolo III MD (pictured)

in 1978 he remains on the faculty as Professor Emeritus The Division is now led by Nelson F SooHoo MD who cares for patients with reconstructive and traumatic conditions of the foot and ankle Dr SooHoo is actively involved in the American

Orthopaedic Foot and Ankle Society and currently serves on the managerial board of the AOFAS Orthopaedic Foot and Ankle Registry initiative Dr Cracchiolo is actively involved in medical student and resident education Lewis Zionts MD from Los Angeles Orthopaedic Hospital focuses on the conservative non-operative treatment of pediatric clubfoot deformity The primary objectives of the Division include providing patient-centered care and advancing the science of foot and ankle surgery

FOOT AND ANKLE SURGERY

The General Orthopaedics section was founded in 2010 by bringing three community orthopaedic surgeons together Peter G Alexakis MD Bruce A Brown MD PhD and S Andrew Schwartz MD Combined they see an average of 650 patient visits per month Dr Brown has a concomitant surgical practice at UCLA Medical Center Santa Monica and the VA involving joint replacement and trauma cases The service is dedicated to facilitating timely access to orthopaedic consultation treatment and referral to appropriate UCLA orthopaedic subspecialists

GENERAL ORTHOPAEDICS

Dr Jung joined us in April 2011 from the Universal Pain Management center in Palmdale CA He specializes in physical medicine amp rehabilitation and interventional pain management

Dr Farrell joined us in August 2011 from the University of Medicine and Dentistry of New Jersey He specializes in trauma surgery

Dr Boguszewski joined us in January 2012 from the University of Cincinnati He specializes in biomechanics research

Dr Daubs joined us in March 2012 from the University of Utah He specializes in spine and deformity surgeon in adults and children

Dr Bukata joined us in April 2012 from the University of Rochester She specializes in musculoskeletal oncology and osteoporosis

Dr Vigil joined us in March 2013 from Kaiser Los Angeles He specializes in sports medicine and non-operative orthopaedics

9

General orthopaedic referrals are seen at both the Westwood and Santa Monica facilities Urgent same-day consultations are accommodated by these three physicians

The UCLA hand surgery service founded by Roy Meals MD (pictured) in 1979 is nationally recognized as one of the most successful truly integrated orthopaedic and plastic surgery hand surgery programs in the country Dr Meals is a clinical professor of hand surgery with clinical areas of expertise in elbow surgery thumb basal joint arthritis and Dupuytrenrsquos disease He is the former president of the American Society for Surgery of the Hand and the editor-in-chief for the Journal of Hand Surgery The hand service provides the full spectrum of hand surgery including surgery for complex reconstructions tendon transfers trauma rheumatoid arthritis compression neuropathies congenital hand differences scleroderma elbow nerve injuries Dupuytrenrsquos contracture and tumors The UCLA hand service has performed the first hand transplantation in the Western United States under the direction of Dr Kodi Azari one of the most experienced reconstructive transplant surgeons The hand team covers UCLA Santa Monica-UCLA Wadsworth VA Olive View-UCLA and Los Angeles Shriners Medical Centers The hand fellowship continues to be one of the most highly ranked fellowships in the country with our graduating fellows universally reporting an excellent training experience

HAND SURGERY

Prosper Benhaim MD now the Division Chief of Hand Surgery at UCLA and Olive View-UCLA Medical Centers joined the Department in 1998 He has numerous local and national committee positions including an editorial position for the Journal of the American Society for Surgery of the

Hand Dr Benhaim has a national reputation as an educator and has been a leader in the treatment of Dupuytrenrsquos disease Kodi Azari MD came to UCLA from the University of Pittsburgh Medical Center in 2008 Dr Azari has been involved in both clinical and laboratory research for more than 18 years and is the author of numerous research articles book chapters and presentations He lectures extensively both nationally and internationally on hand surgery as well as plastic surgery Dr Azari is the surgical director of the newly established UCLA Hand Transplant Program In 2011 he led a team of Surgeons at Ronald Reagan UCLA Medical Center that performed the first hand transplant in the western United States in an operation that lasted 14-12 hours and concluded on Saturday March 5 The transplant was performed on a 26-year-old woman from northern California who lost her right hand in a traffic accident nearly five years before UCLA is only the fourth center in the nation to offer this procedure and the first west of the Rockies It was the 13th hand transplant surgery performed in the United States Dr Azari has been one of the lead surgeons on six hand transplantation operations including the first double hand transplantation and first arm transplantation performed in the United States (wwwhandtransplantuclaedu) Scott Mitchell MD is an Assistant Professor and former outstanding UCLA resident and fellow who joined the faculty in 2009 He performs complex hand wrist and elbow surgery at UCLA Santa Monica-UCLA Medical Center and the West Los Angeles Veterans Affairs Hospital Drs Benhaim Azari and Mitchell all completed their hand fellowships at UCLA

The joint replacement program was founded in 1971 by Harlan Amstutz MD (pictured on next page) who is now an emeritus faculty member and actively practices at St Vincent Medical Center Bert Thomas MD is now the Division Chief and

JOINT REPLACEMENT

9

General orthopaedic referrals are seen at both the Westwood and Santa Monica facilities Urgent same-day consultations are accommodated by these three physicians

The UCLA hand surgery service founded by Roy Meals MD (pictured) in 1979 is nationally recognized as one of the most successful truly integrated orthopaedic and plastic surgery hand surgery programs in the country Dr Meals is a clinical professor of hand surgery with clinical areas of expertise in elbow surgery thumb basal joint arthritis and Dupuytrenrsquos disease He is the former president of the American Society for Surgery of the Hand and the editor-in-chief for the Journal of Hand Surgery The hand service provides the full spectrum of hand surgery including surgery for complex reconstructions tendon transfers trauma rheumatoid arthritis compression neuropathies congenital hand differences scleroderma elbow nerve injuries Dupuytrenrsquos contracture and tumors The UCLA hand service has performed the first hand transplantation in the Western United States under the direction of Dr Kodi Azari one of the most experienced reconstructive transplant surgeons The hand team covers UCLA Santa Monica-UCLA Wadsworth VA Olive View-UCLA and Los Angeles Shriners Medical Centers The hand fellowship continues to be one of the most highly ranked fellowships in the country with our graduating fellows universally reporting an excellent training experience

HAND SURGERY

Prosper Benhaim MD now the Division Chief of Hand Surgery at UCLA and Olive View-UCLA Medical Centers joined the Department in 1998 He has numerous local and national committee positions including an editorial position for the Journal of the American Society for Surgery of the

Hand Dr Benhaim has a national reputation as an educator and has been a leader in the treatment of Dupuytrenrsquos disease Kodi Azari MD came to UCLA from the University of Pittsburgh Medical Center in 2008 Dr Azari has been involved in both clinical and laboratory research for more than 18 years and is the author of numerous research articles book chapters and presentations He lectures extensively both nationally and internationally on hand surgery as well as plastic surgery Dr Azari is the surgical director of the newly established UCLA Hand Transplant Program In 2011 he led a team of Surgeons at Ronald Reagan UCLA Medical Center that performed the first hand transplant in the western United States in an operation that lasted 14-12 hours and concluded on Saturday March 5 The transplant was performed on a 26-year-old woman from northern California who lost her right hand in a traffic accident nearly five years before UCLA is only the fourth center in the nation to offer this procedure and the first west of the Rockies It was the 13th hand transplant surgery performed in the United States Dr Azari has been one of the lead surgeons on six hand transplantation operations including the first double hand transplantation and first arm transplantation performed in the United States (wwwhandtransplantuclaedu) Scott Mitchell MD is an Assistant Professor and former outstanding UCLA resident and fellow who joined the faculty in 2009 He performs complex hand wrist and elbow surgery at UCLA Santa Monica-UCLA Medical Center and the West Los Angeles Veterans Affairs Hospital Drs Benhaim Azari and Mitchell all completed their hand fellowships at UCLA

The joint replacement program was founded in 1971 by Harlan Amstutz MD (pictured on next page) who is now an emeritus faculty member and actively practices at St Vincent Medical Center Bert Thomas MD is now the Division Chief and

JOINT REPLACEMENT

10

was a previous UCLA resident (class of 1984) and fellow of the Hospital for Special Surgery and UCLA He joined the faculty in 1985 has served on the board of Clinical Orthopaedics and Related Research for the past ten years and has been in

the Presidential line of the Association of Bone and Joint Surgeons for the past five years Current research areas include assessment of the potential adverse effects of metal on metal hips and pursuing biological and less invasive methods of treating arthritic hip knee and shoulder joints Benjamin Bengs MD joined the faculty in 2007 after completing orthopaedic surgery training from the Harvard Combined Orthopaedic Surgery Residency Program and a joint replacement fellowship here at UCLA He specializes in complex joint replacement and fragility fractures In 2010 Dr Bengs received a Career Development Awardfrom the Orthopedic Research amp Education Foundation in Total Joint and Trauma Surgery for ldquoProximal Femoral Bone Loss and Femoral Stem Stability in Total Hip Arthroplastyrdquo Francis Cyran MD completed his orthopaedic oncology fellowship here at UCLA in 2005 and has been on faculty since then specializing in joint replacement and tumor surgery Dr Cyranrsquos teaching evaluations from the residents are consistently among the highest in the group and he recently was awarded a prestigious teaching award from the UCLA residents Bruce Brown MD PhD joined the UCLA faculty in 2010 and provides general and trauma coverage in addition to joint replacement services James V Luck Jr MD is a senior faculty member in joint replacement and one of the world leaders in research and treatment of hemophilic arthropathy Dr Luck is our residency Program Director and former President and Chief Executive Officer of the Los Angeles Orthopaedic Hospital He has also beenthe President and Director of the

American Board of Orthopaedic Surgery Peter Alexakis MD joined the UCLA faculty in 2010 and is one of our leading general orthopaedic surgeons who provides care for our general orthopaedic and joint replacement patients

The orthopaedic oncology program at UCLA was founded in 1975 by Todd Grant MD (Orthopaedics 1940-1996 pictured) and Fred Eilber MD (Surgical Oncology) The program was taken over in 1980 by Division Chief Jeffrey Eckardt MD UCLA residency class of 1979 who has expertise in limb salvage surgery using endoprostheses Recent additions to the Division have included Francis Cyran MD Assistant Clinical Professor who joined the faculty in 2005 He maintains active oncology and joints services at Santa Monica and Ronald Reagan UCLA Medical Centers and is a highly-valued member of our teaching faculty who was awarded the Faculty Teaching Award in 2011 by the residents Susan Bukata MD Associate Professor joined us in April 2012 from the University of Rochester and specializes in oncology osteoporosis and bone fragility Nicholas Bernthal MD will join us in August 2013 after his oncology fellowship at the University of Utahrsquos Huntsman Cancer Institute

MUSCULOSKELETAL ONCOLOGY

Our oncology program is part of a multidisciplinary Tumor Board at UCLA that began in 1990 This Board meets weekly and since then more than 16000 cases have been discussed including 7502 new patients and 8255 surgical cases Tumor Board now includes a dedicated surgical pathologist radiologist medical oncologist pediatric oncologist thoracic oncologist surgical oncologists Drs Fred and Fritz Eilber and our orthopaedic oncologists The UCLA orthopaedic oncology program is most noted for its limb-salvage efforts using endoprostheses The members of the multidisciplinary Tumor Board have all been published widely within their own

11

disciplines on all aspects of clinical diagnosis and management for patients with bone and soft tissue tumors

The UCLA Spine program was started in 1972 by Edgar Dawson MD (1936-2003 UCLA residency class of 1971 pictured) and continues to provide clinical services for patients with spinal pathologies and fulfillment of our vision The Chief of the

Orthopaedic Spine Service Jeffrey C Wang MD (UCLA residency class of 1996) continues to direct one of the most prominent spine fellowships in the country and is happy to announce the ongoing matching of their top choices in our spine fellowship They also have a comprehensive Spine Interventional Pain program that is considered a top fellowship We are happy to announce the opening of a new stand-alone spine center that is the culmination of years of planning design and building of a state-of-the-art facility This facility opened in July 2012 and houses the combined spine faculty of UCLA including Orthopaedic Surgeons Neurosurgeons and Physical Medicine Interventional Pain Management specialists In addition the center houses a focused outpatient physical therapy facility

ORTHOPAEDIC SPINE SURGERY

The faculty are extremely excited about the support and vision of leadership to be able to create such a comprehensive and beautifully designed facility In addition to faculty members A Nick Shamie MD and David Fish MD they have also recently added two new members Michael Daubs MD (spinal deformity surgery) and Jae Jung MD (interventional pain management) to the UCLA Spine program Together the faculty will continue to provide expertise in the comprehensive conservative and operative treatments of the patients

The spine team is extremely active in both basic science research and clinical research The team is proud to announce that they were awarded one of the outstanding paper awards from The Spine Journal in the past year for their work on Cost and Utilization of Conservative Management of Lumbar Disc Herniation Prior to Surgical Discectomy They continue to attract international surgeons to the laboratory and currently have seven international surgeons working in the spine center with basic science and clinical projects They are happy to continue to be leaders in the care of their patients with the latest surgical technologies and techniques interventional injections and pain management and the comprehensive non-operative care and rehabilitation for patients with spinal disorders They are dedicated to the ongoing teaching research and clinical care for their patients

Robert Pedowitz MD PhD (pictured top) and John Adams MD (pictured middle) formalized the osteoporosis program in 2009 It has evolved into the UCLA Metabolic Bone Disease and Osteoporosis Center that is led by Aurelia

Nattiv MD (pictured bottom) Professor in the Departments of Orthopaedic Surgery and Family Medicine Dr Nattiv is a certified clinical densitometrist and oversees the operation of the dual energy X-ray absorptiometry (DXA) in addition

to the clinical services of the Center She has received international recognition for her work in the area of bone health concerns in young women with disordered eating amenorrhea and osteoporosis (the female athlete triad) Dr Nattiv also has

participated in studies by the National Institute of

OSTEOPOROSISMETABOLIC BONE DISEASE

12

Health (NIH) assessing risk factors for osteoporotic fracture in older women (the Leisure World Cohort Study) as well as studies evaluating optimal referral interventions for post-fracture patients Additional members of the metabolic bone team include Dr Adams in addition to Susan Bukata MD Benjamin Bengs MD and Freda Hannafon FNP-C The Center provides comprehensive care for patients with osteoporosis including diagnosis and treatment The metabolic bone team includes physicians in the fields of endocrinology geriatrics sports medicine and orthopaedic surgery The team works closely with the patientrsquos own referring physician to optimize bone health and prevent future fractures When referring patients to the Center physicians can request only a DXA for accurate assessment of bone health or refer patients for complete evaluation and consultation with UCLArsquos team of experts for interpretation of test results and recommendations for fracture prevention In addition to working closely with the patientrsquos primary care physician the comprehensive team will often include a physical therapist who specializes in balance and fall prevention occupational therapists who help patients with the activities of daily life and dietitians who provide guidance in nutrition The metabolic bone team has also worked closely with the UCLA Faculty Practice Group to alert physicians of their patients who have had low impact fragility fractures in the efforts to facilitate diagnosis and treatment of osteoporosis in a university-wide fracture protocol program and adherence to osteoporosis-related metrics John S Adams MD is an endocrinologist and internationally-recognized expert in vitamin D and an authority in the hormones that control skeletal homeostasis He is Vice Chair of Research in the UCLA-Orthopaedic Hospital Research Center (OHRC) and Associate Director of the newly minted NIH-funded Clinical and Translational Science Institute at UCLA Dr Adams is a renowned

clinician-scientist being continuously funded for the last 32 years by the NIH for both basic science and clinical research He currently serves as an Associate Editor for the Journal of Bone and Mineral Research and as a member of the Council of the American Society for Bone and Mineral Research Susan Bukata MD Associate Professor of Orthopaedic Surgery is an orthopaedic surgeon and new addition to the Department in 2012 Dr Bukata specializes in metabolic bone disease and orthopaedic oncology She helped develop the geriatric fracture center algorithm from the University of Rochester that has become the best practices standard for inpatient fragility fracture care She is a translational research specialist working with agents that stimulate and modulate fracture healing including teriparatide Her clinical practice in metabolic bone diseases includes not only osteoporosis patients but also children and adults with fragility fracture problems associated with genetic and developmental diseases such as osteogenesis imperfecta cerebral palsy and the muscular dystrophies She cares for patients of all ages including many patients who do not fit standard care algorithms

The pediatric orthopaedic program was started in 1979 by William Oppenheim MD (pictured) who also founded the Center for Cerebral Palsy in 1995 Dr Oppenheim recently joined Los Angeles Orthopaedic Hospital which has been associated with UCLA since 1996 as part of the alliance

agreement The subspecialty pediatric clinics at the downtown campus of LAOH are some of the busiest in the country with over 55000 pediatric orthopaedic visits last year Families from around the region seek out our facultyrsquos expertise in cerebral palsy (Dr Oppenheim) clubfoot (Lewis Zionts MD) sports medicine (Heather Gillespie

PEDIATRIC ORTHOPAEDICS

13

MD MPH and Richard Bowen MD UCLA residency class of 2001) trauma (Mauricio Silva MD) tumor (Francis Cyran MD) and scoliosis (Richard Bowen MD and Anthony Scaduto MD UCLA residency class of 2002) Our multidisciplinary clinics offer unique comprehensive care for spina bifida muscle disease osteogenesis imperfecta hemophilia and limb deficiencyamputation A skeletal dysplasia clinic is due to open this year (Pictured from left to right Oppenheim Zionts Scaduto Bowen Silva)

The Division of Sports Medicine was founded in 1971 by Gerald Finerman MD (pictured) Dr Finerman has been on the UCLA faculty since then and was the former Department Chair from 1996-2009 He will join the Emeritus faculty in July 2013 and continue his involvement with medical student resident and fellow teaching The Division is now led by David McAllister MD Division Chief and Program Director of the Sports Medicine Fellowship Program Additional sports medicine faculty members include Sharon Hame MD Professor who has a special interest in hip arthroscopy and works part-time at the West Los Angeles VA Professor Robert Pedowitz MD PhD was Department Chair from 2009-2010 and specializes in shoulder and knee surgery and research in arthroscopic simulation Frank

Petrigliano MD Assistant Professor and UCLA resident class of 2009 focuses his clinical and research activity in shoulder surgery and sports medicine Dr Petrigliano studies the basic science of rotator cuff disease at UCLA is clinical faculty at both the VA and Olive View Medical Center As of March 1st 2013 Seth Gamradt MD (UCLA resident class of 2006) will join the USC faculty as Associate Professor and Director of Orthopaedic Athletic Medicine for USC Athletics Dr Gamradt is a specialist in shoulder surgery and sports medicine with interests in shoulder replacement and knee ligament reconstruction Still a friend in spite of his ldquodefectionrdquo we wish him the best of luck and appreciate this unique opportunity for him The sports medicine faculty members see patients at both the Westwood and Santa Monica campuses These physicians serve as the exclusive provider of medical services to the UCLA Athletic Department They continue to provide care for more than 700 UCLA intercollegiate athletes at the Acosta Athletic Training Complex and provide musculoskeletal care at the Arthur Ashe Student Health and Wellness Center

SPORTS MEDICINE

The Division of Non-Operative Sports Medicine continues to be active in advancing clinical care both the office as well as on the sidelines with the UCLA Bruins In addition the Division conducts important research and members of the faculty hold national leadership positions The Division has also been active in using musculoskeletal ultrasound at the point of care for office-based procedures and diagnosis Division Chief John DiFiori MD recently served as Co-Director of the very successful UCLA Musculoskeletal Ultrasound Course which featured a cadaver lab for procedural training In the research arena Dr DiFiori is participating in a multicenter study on the long-term effects of sport-related concussion that was recently funded by the NCAA Aurelia Nattiv MD Director of the Osteoporosis Center recently published a five-year study on restoration of normal menses in college athletes with menstrual

SPORTS MEDICINENON-OPERATIVE ORTHOPAEDICS

14

disturbances Heather Gillespie MD MPH Director of the Pediatric Sports Medicine Service at Orthopaedic Hospital has recently completed research examining sports-related injuries presenting to an inner city underserved population Daniel Vigil MD joins the faculty in March from Kaiser Los Angeles The UCLA primary care sports medicine fellowship program attracts outstanding applicants from across the country

Though the AO technique was brought to UCLA in 1978 by Dr Tony Headly it was Eric Johnson MD FRCSI (Hon) (UCLA residency class of 1981) who

established the orthopaedic trauma program in 1982 Dr Johnson is the Division Chief and he specializes in orthopaedic traumatology and fracture surgery He serves as a Member of the Board of Directors of the AO Foundation and was awarded an Honorary Fellowship in the Royal College of Surgeons in Ireland on July 13 2009 Dublin Ireland (pictured above) In 2011 Dr Johnson was the guest of honor at the 23rd at the Letournel Pelvic and Acetabular Fracture Course in Paris France In September 2011 he gave the Keynote Lecture 30 Years of Acetabular Fracture Surgery and traveled to Ireland in November 2011 to give four lectures at the 10th Current Controversies in Trauma Management Royal College of Surgeons Dr Johnson continues to travel lecture and teach as part of his commitment to the AO Foundation

TRAUMA SURGERY

Devon Jeffcoat MD (UCLA resident class of 2009) joined the faculty at UCLA in 2010 after completing his fellowship at the Hospital for Special Surgery in New York under the tutelage of Dr David Helfet Dr Jeffcoat volunteered his time during the earthquake crisis in Haiti He has already developed a busy trauma surgery practice and became a mainstay for orthopaedics at the Westwood campusrsquo Level I trauma center Ronald Reagan-UCLA Medical Center Eric D Farrell MD joined the UCLA orthopaedic trauma staff in August 2011 He previously spent more than six years as Assistant Director of Orthopaedic Trauma at Cooper University Hospital in Camden NJ His training consisted of a trauma fellowship at Harborview Medical Center in Seattle WA AO Fellowship in Salzburg Austria and an Ilizarov Fellowship in Lecco Italy He has a particular interest in nonunions and deformity correction

15

ORTHOPAEDIC RESEARCH

In 2011 Orthopaedic Hospital celebrated its 100-year anniversary (see appended photos below of OH in 1917 and 2011) For the last two decades the century-old research mission at the Orthopaedic Hospital has flourished under the direction of Harry McKellop PhD and his discovery of orthopaedic device components with

greatly improved durability and longevity The standard for excellence in orthopaedic research at UCLA was set by Marshall Urist MD who discovered and ushered in the clinical use of bone morphogenetic protein to build back human bone where it was needed to make new bone for skeletal stability 1998 saw the alliance of the UCLA Department of Orthopaedic Surgery and Orthopaedic Hospital with a commitment to preserve the rich patient-oriented research mission embraced by both

HISTORICAL PERSPECTIVE

2007 witnessed the first step of the alliancersquos vision to expand the mission of the two institutions to become among the best orthopaedic research centers in the world with the opening of the Cesar Pelli-designed-Orthopaedic Hospital Research Center at the heart of the Court of Sciences on the UCLA Westwood campus (pictured on next page) As Director of the Orthopaedic Hospital Research Center John Adams MD (pictured below) was charged with realizing this expanded vision by mounting a bold recruiting effort to create an interschool (ie medicine engineering dentistry

etc) transdisciplinary

extramurally-funded bench-to-bedside team science approach to childhood and

adult musculoskeletal disease The recruitment effort culminated this spring with the addition of 22 new faculty members from around the world to laboratories in the Orthopaedic Hospital Research Center

RESEARCH BASIC SCIENCE AND TRANSLATIONAL

Highlights of this expansion from 2007 include 1) a 10-fold increase to $55M in annual peer-reviewed grant funding coming to the Department moving the Department to number seven on the list of the top NIH-granted departments in the country 2) the first ever NIH training grant in Orthopaedic Surgery for UCLA principled by John Adams MD and Karen Lyons PhD (pictured above) representing the only such training grant in orthopaedic surgery west of St Louis 3) the first ever large-scale grant ($56M total) from the California Institute for Regenerative Medicine for bone regeneration research principled by Chia Soo MD and Bruno Peault PhD and 4) presentation to the Department of Orthopaedic Surgery of an $82 million Clinical and Translational Science Award by the NIH the largest single grant to the David Geffen School of Medicine at UCLA None of these efforts would have been possible without advice

16

support and teamwork contributed by the Broad Stem Cell Institute the Jonsson Comprehensive Cancer Center the Department of Molecular Cell and Developmental Biology in the UCLA College of Letters and Science and the Clinical and Translational Science Institute

The Orthopaedic Hospital Research Center on the Westwood campus provides a fertile environment for our researchers

and clinicians to innovate and collaborate in pediatric orthopaedic science Karen Lyons PhD has received international awards for her breakthrough work in skeletal development and growth-plate biology while Deborah Krakow MD and Dan Cohn PhD (both pictured above) have identified several key genetic mutations that cause dwarfism These discoveries have lead to a better understanding of bone diseases that affect children and are the basis for novel future treatments Our clinicians and scientists are also focused on translational research that enhances orthopaedic treatment for children by improving surgical techniques and non-surgical care In collaboration with the pediatric spine surgeons Sophia Sangiorgio PhD and Edward Ebramzadeh PhD have developed an experimental model to test and compare surgical techniques used in scoliosis surgery Their work will be presented at this yearrsquos Scoliosis Research Society meeting Mauricio Silva MD maintains one of the largest prospective pediatric trauma registries in the country The analysis of this database has resulted in several recent JBJS publications that are likely to shape the evidence-based treatment of pediatric elbow fractures He and Fabrizio Billi PhD are also collaborating with scientists in UCLArsquos School of Engineering to develop a wireless technology that can improve the fit and function of casts used to treat childrenrsquos fractures In the field of motor disorders Eileen Fowler PhD PT (pictured) and

her team have recently developed and validated a method to measure selective motor control that can predict the success of surgery for patients with cerebral palsy We are proud of the

UCLAOrthopaedic Hospital partnership and the significant contributions our pediatric orthopaedic clinicians and scientists have made We look forward to further advances that help children overcome their musculoskeletal injuries and disease The Orthopaedic Hospital Research Center remains dedicated to its founding principles First that major advances in understanding the pathobiology and management of those diseases that are most frequently encountered by the practicing orthopaedic surgeon (eg fractures joint instability etc) can be best achieved by teams of scientists with expertise ranging from molecular biology to clinical care of patients Second understanding the developmental events that shape formation of the musculoskeletal system from fetal to adult life will inform us about the deconstruction of the system that happens with aging and disease Third that development of mouse models of common human orthopaedic disease where genes in the mouse can be ldquoknocked outrdquo or amplified will allow us to develop ldquopersonalized-rdquo molecularly-targeted preventative and treatment regimens Finally by bringing the cadre of clinician-scientists into a

17

common practice setting in the new Orthopaedic Hospital in at the Santa Monica-UCLA Medical Center and Orthopaedic Hospital we hope to translate basic discoveries made in the Orthopaedic Hospital Research Center to a new standard of orthopaedic health care for both children and adults

Another study is focusing on bone formation as well as spinal fusion We are utilizing bone graft substitutes along with the appropriate growth factors to optimize the healing of the spinal fusions through the least amount of invasiveness with minimally invasive techniques Our previous studies have shown that with gene therapy we have been able to achieve spinal fusion in a very efficient manner We hope to optimize this with

the use of new bone graft materials with new growth factors in order to obtain 100 spinal fusion ultimately for our patients We hope to start clinical trials in this soon Another study we are looking at is the suppression of tumors One of the growth factors that we have invented in our laboratory here at UCLA has shown an effect to inhibit BMP bone morphogenic growth factors many tumors rely on to grow We have shown the addition of this novel growth factor can suppress the growth of tumor cells We have initiated a project where we are attempting to use this novel protein to inhibit the growth of tumors We ultimately hope that this will act as a new therapeutic method in the fight against cancer A new technology of dynamic MRI imaging will allow us to identify the pathology for patients with spine problems We have previously published over 18 scientific articles looking at the effect of dynamic motion MRI in identifying spinal pathology We are perfecting this technique and hope to institute this as a part of our standard treatment protocol for patients with spinal problems

RESEARCH THE UCLA SPINE PROGRAM The Spine Service continues to explore new areas in both basic science and clinical research in the area of spinal disorders We have a world-class laboratory that continues to attract surgeons on an international level to come and participate in our research efforts We have seven ongoing international fellowships for surgeons to come and collaborate on our research projects One of our publications was named the outstanding paper award this past year by The Spine Journal We recently received an OREF (Orthopaedic Research and Education Foundation) grant for starting a biologics registry for spinal fusion Our basic science efforts encompass several novel projects for regeneration of the spinal tissuesdiscs We are utilizing the most novel gene therapy transfer techniques along with pleuripotent stem cells in order to regenerate the disc Through our previous work of injecting growth factors into disc we have been able to generate these discs in our prior studies We are trying to optimize this effect with the addition of stem cell technology to optimize the number of cells the concentration of growth factors as well as the optimal gene transfer in order to perfect the best technique to regenerate the disc We hope that this will soon move from the animal models into human trials

The Division of Sports Medicine continues to be productive in a number of research areas Our orthopaedic biomechanics lab has expanded with the addition of Daniel Boguszewski PhD Dr Boguszewski obtained his PhD from the University of Cincinnati where he developed expertise with a sophisticated robotic testing apparatus We recently acquired an industrial robot (pictured on next page) for mechanical testing and are looking forward to coupling this exciting new technique with existing techniques pioneered by Keith Markolf PhD Our bioengineers along with Drs David McAllister and Frank Petrigliano have formed a new collaboration with the UCLA Electrical Engineering Department Wireless Health initiative to develop novel ways to measure knee biomechanics and knee injury mechanisms in patients Drs McAllister and Petrigliano have established a lab at the Greater Los Angeles VA Medical Center and continue to collaborate with Ben Wu DDS PhD in the Department of

RESEARCH THE UCLA SPORTS MEDICINE PROGRAM

18

Bioengineering and Patricia Zuk PhD in the Department of Plastic Surgery on tissue engineering for ACL reconstruction and rotator cuff repair Drs Sharon Hame and David McAllister continue to participate in clinical research including outcomes of ACL reconstruction Both are co-investigators in the NIH-funded multicenter ACL Revision Surgery (MARS) study Both also continue to collect and analyze data on primary ACL reconstruction Drs Hame McAllister Gamradt and Petrigliano have all recently completed studies on the incidence of shoulder and knee procedures using the Peardiver database

19

Jeffrey Eckardt MD Professor and Chair Orthopaedic Surgery UCLA

Anthony Scaduto MD Executive Vice Chair and President and CAO LAOH

Jeffrey Wang MD Vice Chair of Clinical Operations Orthopaedic Surgery UCLA

John Adams MD Vice Chair of Research Orthopaedic Surgery UCLA

James Luck MD Residency Program Director Orthopaedic Surgery UCLAOH

FACULTY There are presently 73 faculty members in our Department of Orthopaedic Surgery

Foot and Ankle Surgery Andrea Cracchiolo III MD (Emeritus) Nelson SooHoo MD (Division Chief) Lewis Zionts MD

General Orthopaedics Peter Alexakis MD Bruce Brown MD PhD S Andrew Schwartz MD

Hand Surgery Kodi Azari MD Prosper Benhaim MD (Division Chief) Scott Mitchell MD

Joint Replacement Benjamin Bengs MD Bruce Brown MD PhD Francis Cyran MD Gerald Finerman MD Eric Johnson MD James Luck MD Bert Thomas MD (Division Chief)

Musculoskeletal Oncology Susan Bukata MD Francis Cyran MD Jeffrey Eckardt MD (Division Chief)

Osteoporosis John Adams MD Susan Bukata MD Aurelia Nattiv MD

Pediatric OrthopaedicsOrthopaedic Hospital Richard Bowen MD James Luck MD William Oppenheim MD Anthony Scaduto MD (Division Chief) Mauricio Silva MD Lewis Zionts MD

Spine SurgeryPMampR Richard Bowen MD Michael Daubs MD David Fish MD MPH (PMampR) Jae Jung MD (PMampR) Anthony Scaduto MD A Nick Shamie MD Jeffrey Wang MD (Division Chief)

Sports Medicine Richard Bowen MD Gerald Finerman MD Sharon Hame MD David McAllister MD (Division Chief) Robert Pedowitz MD PhD

Frank Petrigliano MD

Sports Medicine amp Non-Operative Orthopaedics John DiFiori MD (Division Chief) Heather Gillespie MD MPH Aurelia Nattiv MD Daniel Vigil MD

Trauma Surgery Benjamin Bengs MD Eric Farrell MD Devon Jeffcoat MD Eric Johnson MD (Division Chief)

Shriners Hospital Katherine Au MD Robert Cho MD Anna Cuomo MD Kathryn Doughty MD Colin Mosely MD Kit Song MD (Service Chief) Hugh Watts MD

VA Hospital Bruce Brown MD PhD Francis Cyran MD Sharon Hame MD Eric Johnson MD David McAllister MD Scott Mitchell MD Frank Petrigliano MD Nelson SooHoo MD (Service Chief) Bert Thomas MD Steven Zeitzew MD

Research Faculty John Adams MD (Vice Chair of Research) Maria-Grazia Ascenzi PhD Paul Bajaj PhD Fabrizio Billi PhD Daniel Boguszewski PhD Patricia Campbell PhD Daniel Cohn PhD Gay Crooks PhD Edward Ebramzadeh PhD Denis Evseenko MD PhD Eileen Fowler PhD PT Martin Hewison PhD Luisa Iruela-Arispe PhD Deborah Krakow MD Susan Krum PhD Timothy Lane PhD Philip Liu PhD Daniel Lu MD PhD Zhen Lu PhD Karen Lyons PhD Keith Markolf PhD Harry McKellop PhD Shen Pang PhD Sang-Hyun Park PhD Bruno Peault PhD Sophia Sangiorgio PhD Fu Wen Shen PhD B Chia Soo MD Kang Ting DMD Howard Winet PhD Benjamin Wu DDS PhD

20

RECENT FACULTY HONORS AND PUBLICATIONS John Adams MD

1 Vitamin D 3rd Edition Feldman DR Pike JW Adams JS eds San Diego Elsevier Press 2011

2 Chen H Gilbert LC Lu X Liu Z You S Weitzmann MN Nanes MS Adams JS Estrogen response element binding protein stimulates osteoclastogenesis and bone resorption J Bone Min Res 262537-2547 2011 PMCID PMC3417837

3 Fabri M Stenger S Shin D Yuk J Liu PT Realegeno S Lee H Krutzik SR Schenk M Sieling PA Teles R Montoya D Iyer SS Bruns H Lewinsohn DM Hollis BW Hewison M Adams JS Steinmeyer A Zuumlgel U Cheng G Jo E Bloom BR Modlin RL Vitamin D is required for IFN-γ mediated antimicrobial activity of human macrophages Sci Transl Med 3104ra102 2011 PMCID PMC3269210

4 Billi F Benya B Kavanaugh A Adams JS Ebramzadeh E McKellop H The John Charnley Award An accurate and extremely sensitive method to separate display and characterize wear debris part 1ndashpolythylene particles Clin Orthopaed Rel Res 470329-338 2012 PMCID PMC 3254734

5 James AW Pang S Askarinam A Corselli M Zara JN Goyal R Chang L Pan A Shen J Yuan W Stoker D Zhang X Adams JS Ting K Soo C Additive effects of sonic hedgehog and Nell-1 signaling in osteogenic versus adipogenic differentiation of human adipose-derived stromal cells Stem Cells Dev 212170-2178 2012 PMCID PMC3411358

Kodi Azari MD 1 Azari K Imbriglia JE Goitz RJ Shores JT Balk ML

Brandacher G Schneeberger S Gorantla V Lee WPldquoHandTransplantion The Donor and Operationrdquo Journal of Reconstructive Microsurgery (2012) 28(1) 27-34

2 Sue McDiarmid and Kodi Azari ldquoDonor Related Issues in Hand Transplantaionrdquo Hand Clinics (2011) 274 545-54

3 Tristan L Hartzell Prosper Benhaim Joeseph E Imbriglia Jaimie Shores Robert J Goitz Marshall Balk Scott Mitchell Roee Rubinstein Vijay Gorantla Stephan Schneeberger Gerald Brandacher W P Andrew LeeKodi K Azari ldquoSurgical and Technical Aspects of Hand Transplantation ndash Is it Just Another Replantrdquo Hand Clinics (2011) 274 521-30

4 Immune Modulation for Hand Transplantation Changing the Risk-Benefit Balance Brandacher G Gorantla VS Schneeberger S Shores JT Imbriglia JE Azari K Donnenberg AD Cooney DS Losee JE Lee WPA J Healthcare Science Humanities 20111(4)62-68

5 Elaine Horibe Song Afshin Shirazian Brian

Binns Yuedi Fleming Lydia M Ferreira Rod J Rohrich Kodi Azari ldquoBenchmarking academic plastic surgery services in the USrdquo Plastic and Reconstructive Surgery (2012) 129(6)1407-18

Benjamin Bengs MD

1 Bengs BC Sangiorgio SN Ebramzadeh E Achieving Clinically Adequate Stem Fixation Despite Severe Proximal Femoral Bone Loss Poster P039 Orthopedic Research Society Annual Meeting San Fransisco CA 2012

2 Sangiorgio S Knutsen A Kalma J Ebramzadeh E Bengs B Can a Dual-tapered Press-fit Stem be used in Cases with Severe Proximal Femoral Defects AAOS Poster 2043 Annual Meeting in San Francisco CA

3 Sugi M Sheridan K Lewis L Huang MH Nattiv A Kado DM BC Bengs Active referral intervention following fragility fractures leads to enhanced osteoporosis follow-up carerdquo Journal of Osteoporosis (accepted 2012)

4 Sangiorgio S Ebramzadeh E Knutsen A Kalma J Bengs B Can a Dual-tapered Press-fit Stem be used in Cases with Severe Proximal Femoral Defects Journal of Biomaterials and Biomechanics (accepted 2012)

5 Aaron W James Jia Shen Xinli Zhang Michael Chiang Asal Askarinam Raghav Goyal Alan Nguyen Janette N Zara Greg Asatrian Jonguk Chung Benjamin Bengs Cymbeline T Culiat A Simon Turner Howard B Seim III John S Adams Kang Ting Chia Soo Nell-1 Regulates Osteoblast Osteoclast Activity and Activates Wntβ-catenin Signaling A New Cause and Treatment for Osteoporosis (submitted for publication)

Prosper Benhaim MD 1 Benhaim P Anthony JP Lin LYT McCalmont TH

Mathes SJ A long-term study of allogeneic rat hindlimb transplants immunosuppressed with RS-61443 Transplantation 1993 56(4) 911-917

2 Tejwani SG Markolf KL Benhaim P Graft reconstruction of the interosseous membrane in conjunction with metallic radial head replacement a cadaveric study Journal of Hand Surgery 2005 30A(2) 335-342

3 Markolf KL Tejwani SG Benhaim P Effects of wafer resection and hemiresection from the distal ulna on load-sharing at the wrist a cadaveric study Journal of Bone and Joint Surgery 2005 30A(2) 351-358

4 Dragoo JL Lieberman JR Lee RS DeUgarte DA Lee Y Zuk PA Hedrick MH Benhaim P ldquoTissue engineered bone from BMP-2 transduced stem cells derived from human fat Plastic and Reconstructive Surgery 2005 115(6) 1665-1673

21

5 Dragoo JL Carlson G McCormick F Khan-Farooqi H Zhu M Zuk PA Benhaim P Healing full-thickness cartilage defects using adipose-derived stem cells Tissue Engineering 2007 13(7) 1615-1621

Nicholas Bernthal MD

1 Kremen TJ Jr Bernthal NM Eckardt MA Eckardt JJ Giant cell tumor of bone are we stratifying results appropriately Clin Orthop Relat Res 2012 Mar470(3)677-83

2 Bernthal NM Federman N Eilber FR Nelson SD Eckardt JJ Eilber FC Tap WD Long-term results (gt25 years) of a randomized prospective clinical trial evaluating chemotherapy in patients with high-grade operable osteosarcoma Cancer 2012 Dec 1118(23)5888-93 doi 101002cncr27651 Epub 2012 May 30

3 Pribaz JR Bernthal NM Wong TC Silva M Lateral spurring (overgrowth) after pediatric lateral condyle fractures J Pediatr Orthop 2012 Jul-Aug32(5)456-60

4 Silva M Knutsen AR Kalma JJ Borkowski SL Bernthal NM Spencer HT Sangiorgio SN Ebramzadeh E Biomechanical Testing of Pin Configurations in Supracondylar Humeral Fractures The Effect of Medial Column Comminution J Orthop Trauma 2012 Aug 28 [Epub ahead of print]

5 Niska JA Meganck JA Pribaz JR Shahbazian JH Lim E Zhang N Rice BW Akin A Ramos RI Bernthal NM Francis KP Miller LS Monitoring bacterial burden inflammation and bone damage longitudinally using optical and μCT imaging in an orthopaedic implant infection in mice PLoS One 20127(10)e47397 doi 101371journalpone0047397 Epub 2012 Oct 17

Rick Bowen MD

1 POSNA Traveling Fellowship Recipient (2008) 2 Bowen RE Scaduto AA Banuelos S Does early

thoracic fusion exacerbate preexisting restrictive lung disease in congenital scoliosis patients J Pediatr Orthop 28 506-511 2008

3 Bowen RE Scaduto AA Banuelos S Decreased body mass index and restrictive lung disease in congenital thoracic scoliosis J Pediatr Orthop 28665-8 2008

4 Bowen RE Gardner S Scaduto AA Eagan M Beckstead J Efficacy of intraoperative cell salvage systems in pediatric idiopathic scoliosis patients undergoing posterior spinal fusion with segmental spinal instrumentationSpine (Phila Pa 1976) 35246-51 2010

5 Bowen RE Knee injuries in the youth athlete Curr Orthop Prac 2012 23 422-428

Susan Bukata MD 1 Houck J Kneiss J Bukata SV Puzas JE Analysis of

vertical ground reaction force variables during a Sit to Stand task in participants recovering from a hip fracture Clin Biomech 2011 Jun 26(5) 470-6

2 Takahata M Awad HA OrsquoKeefe RJ Bukata SV Schwarz EM Endogenous tissue engineering PTH therapy for skeletal repair Cell Tissue Res 2011 May 31 [Epub ahead of print]

3 Kates SL Bukata SV DiGiovanni BF Friedman SL et al A guide to improving the care of patients with fragility fractures Geriatric Orthopaedic Surgery amp Rehabilitation 2011 2(1) 5-37

4 Sampson ER Chen D Schwarz EM Bukata SV OrsquoKeefe RJ Awad H Puzas JE Zuscik MJ Rosier RN Teriparatide as a chondro-regenerative therapy for injury-induced knee osteoarthritis Science Translational Medicine 2011 Sept 21 3(101) 101ra93

5 Kneiss JA Houck JR Bukata SV Puzas JE Influence of Upper Extremity Assistance on Lower Extremity Force Application Symmetry in Individuals Post-Hip Fracture During the Sit-to-Stand Task Journal of Orthopaedic amp Sports Physical Therapy 2012 May 42(5) 474-481

Michael Daubs MD

1 Patton CM Hung M Lawrence BD Patel A Woodbury AM Brodke DS Daubs MD Psychological Distress in a Department of Veteransrsquo Affairs Spine Patient Population The Spine J 2011 Nov 15 (epub ahead of print)

2 Daubs MD Lenke LG Kim YJ Cheh G Stobbs G Bridwell KH Does Correction of Preoperative Coronal Imbalance Make a Difference in Outcomes of Adult Deformity Patients Accepted for publication Spine June 2012

3 Daubs MD Patel AA Lawrence BD Brodke DS Excision of the Posterior Longitudinal Ligament During Anterior Cervical Corpectomy A Biomechanical Study Accepted for publication September 12 2012J Spinal Disorders

4 Daubs MD Lenke LG Cheh G Bridwell KH Kim YJ Stobbs G Decompression Alone Versus Decompression with Limited Fusion for the Treatment of Degenerative Lumbar Scoliosis in the Elderly Patient Accepted for publication Sept 5 2012Evidence Based Spine Journal

5 Tan Y Montgomery SR Aghdasi BG Inoue H Kaner T Tian H Terrell R Zhang X Wang JC Daubs MD The Effect of Corticosteroid Administration on Soft Tissue Inflammation Associated with rhBMP-2 use in a Rodent Model of Inflammation Spine (Phila Pa 1976) 2012 Nov 28 [Epub ahead of print]

11

disciplines on all aspects of clinical diagnosis and management for patients with bone and soft tissue tumors

The UCLA Spine program was started in 1972 by Edgar Dawson MD (1936-2003 UCLA residency class of 1971 pictured) and continues to provide clinical services for patients with spinal pathologies and fulfillment of our vision The Chief of the

Orthopaedic Spine Service Jeffrey C Wang MD (UCLA residency class of 1996) continues to direct one of the most prominent spine fellowships in the country and is happy to announce the ongoing matching of their top choices in our spine fellowship They also have a comprehensive Spine Interventional Pain program that is considered a top fellowship We are happy to announce the opening of a new stand-alone spine center that is the culmination of years of planning design and building of a state-of-the-art facility This facility opened in July 2012 and houses the combined spine faculty of UCLA including Orthopaedic Surgeons Neurosurgeons and Physical Medicine Interventional Pain Management specialists In addition the center houses a focused outpatient physical therapy facility

ORTHOPAEDIC SPINE SURGERY

The faculty are extremely excited about the support and vision of leadership to be able to create such a comprehensive and beautifully designed facility In addition to faculty members A Nick Shamie MD and David Fish MD they have also recently added two new members Michael Daubs MD (spinal deformity surgery) and Jae Jung MD (interventional pain management) to the UCLA Spine program Together the faculty will continue to provide expertise in the comprehensive conservative and operative treatments of the patients

The spine team is extremely active in both basic science research and clinical research The team is proud to announce that they were awarded one of the outstanding paper awards from The Spine Journal in the past year for their work on Cost and Utilization of Conservative Management of Lumbar Disc Herniation Prior to Surgical Discectomy They continue to attract international surgeons to the laboratory and currently have seven international surgeons working in the spine center with basic science and clinical projects They are happy to continue to be leaders in the care of their patients with the latest surgical technologies and techniques interventional injections and pain management and the comprehensive non-operative care and rehabilitation for patients with spinal disorders They are dedicated to the ongoing teaching research and clinical care for their patients

Robert Pedowitz MD PhD (pictured top) and John Adams MD (pictured middle) formalized the osteoporosis program in 2009 It has evolved into the UCLA Metabolic Bone Disease and Osteoporosis Center that is led by Aurelia

Nattiv MD (pictured bottom) Professor in the Departments of Orthopaedic Surgery and Family Medicine Dr Nattiv is a certified clinical densitometrist and oversees the operation of the dual energy X-ray absorptiometry (DXA) in addition

to the clinical services of the Center She has received international recognition for her work in the area of bone health concerns in young women with disordered eating amenorrhea and osteoporosis (the female athlete triad) Dr Nattiv also has

participated in studies by the National Institute of

OSTEOPOROSISMETABOLIC BONE DISEASE

12

Health (NIH) assessing risk factors for osteoporotic fracture in older women (the Leisure World Cohort Study) as well as studies evaluating optimal referral interventions for post-fracture patients Additional members of the metabolic bone team include Dr Adams in addition to Susan Bukata MD Benjamin Bengs MD and Freda Hannafon FNP-C The Center provides comprehensive care for patients with osteoporosis including diagnosis and treatment The metabolic bone team includes physicians in the fields of endocrinology geriatrics sports medicine and orthopaedic surgery The team works closely with the patientrsquos own referring physician to optimize bone health and prevent future fractures When referring patients to the Center physicians can request only a DXA for accurate assessment of bone health or refer patients for complete evaluation and consultation with UCLArsquos team of experts for interpretation of test results and recommendations for fracture prevention In addition to working closely with the patientrsquos primary care physician the comprehensive team will often include a physical therapist who specializes in balance and fall prevention occupational therapists who help patients with the activities of daily life and dietitians who provide guidance in nutrition The metabolic bone team has also worked closely with the UCLA Faculty Practice Group to alert physicians of their patients who have had low impact fragility fractures in the efforts to facilitate diagnosis and treatment of osteoporosis in a university-wide fracture protocol program and adherence to osteoporosis-related metrics John S Adams MD is an endocrinologist and internationally-recognized expert in vitamin D and an authority in the hormones that control skeletal homeostasis He is Vice Chair of Research in the UCLA-Orthopaedic Hospital Research Center (OHRC) and Associate Director of the newly minted NIH-funded Clinical and Translational Science Institute at UCLA Dr Adams is a renowned

clinician-scientist being continuously funded for the last 32 years by the NIH for both basic science and clinical research He currently serves as an Associate Editor for the Journal of Bone and Mineral Research and as a member of the Council of the American Society for Bone and Mineral Research Susan Bukata MD Associate Professor of Orthopaedic Surgery is an orthopaedic surgeon and new addition to the Department in 2012 Dr Bukata specializes in metabolic bone disease and orthopaedic oncology She helped develop the geriatric fracture center algorithm from the University of Rochester that has become the best practices standard for inpatient fragility fracture care She is a translational research specialist working with agents that stimulate and modulate fracture healing including teriparatide Her clinical practice in metabolic bone diseases includes not only osteoporosis patients but also children and adults with fragility fracture problems associated with genetic and developmental diseases such as osteogenesis imperfecta cerebral palsy and the muscular dystrophies She cares for patients of all ages including many patients who do not fit standard care algorithms

The pediatric orthopaedic program was started in 1979 by William Oppenheim MD (pictured) who also founded the Center for Cerebral Palsy in 1995 Dr Oppenheim recently joined Los Angeles Orthopaedic Hospital which has been associated with UCLA since 1996 as part of the alliance

agreement The subspecialty pediatric clinics at the downtown campus of LAOH are some of the busiest in the country with over 55000 pediatric orthopaedic visits last year Families from around the region seek out our facultyrsquos expertise in cerebral palsy (Dr Oppenheim) clubfoot (Lewis Zionts MD) sports medicine (Heather Gillespie

PEDIATRIC ORTHOPAEDICS

13

MD MPH and Richard Bowen MD UCLA residency class of 2001) trauma (Mauricio Silva MD) tumor (Francis Cyran MD) and scoliosis (Richard Bowen MD and Anthony Scaduto MD UCLA residency class of 2002) Our multidisciplinary clinics offer unique comprehensive care for spina bifida muscle disease osteogenesis imperfecta hemophilia and limb deficiencyamputation A skeletal dysplasia clinic is due to open this year (Pictured from left to right Oppenheim Zionts Scaduto Bowen Silva)

The Division of Sports Medicine was founded in 1971 by Gerald Finerman MD (pictured) Dr Finerman has been on the UCLA faculty since then and was the former Department Chair from 1996-2009 He will join the Emeritus faculty in July 2013 and continue his involvement with medical student resident and fellow teaching The Division is now led by David McAllister MD Division Chief and Program Director of the Sports Medicine Fellowship Program Additional sports medicine faculty members include Sharon Hame MD Professor who has a special interest in hip arthroscopy and works part-time at the West Los Angeles VA Professor Robert Pedowitz MD PhD was Department Chair from 2009-2010 and specializes in shoulder and knee surgery and research in arthroscopic simulation Frank

Petrigliano MD Assistant Professor and UCLA resident class of 2009 focuses his clinical and research activity in shoulder surgery and sports medicine Dr Petrigliano studies the basic science of rotator cuff disease at UCLA is clinical faculty at both the VA and Olive View Medical Center As of March 1st 2013 Seth Gamradt MD (UCLA resident class of 2006) will join the USC faculty as Associate Professor and Director of Orthopaedic Athletic Medicine for USC Athletics Dr Gamradt is a specialist in shoulder surgery and sports medicine with interests in shoulder replacement and knee ligament reconstruction Still a friend in spite of his ldquodefectionrdquo we wish him the best of luck and appreciate this unique opportunity for him The sports medicine faculty members see patients at both the Westwood and Santa Monica campuses These physicians serve as the exclusive provider of medical services to the UCLA Athletic Department They continue to provide care for more than 700 UCLA intercollegiate athletes at the Acosta Athletic Training Complex and provide musculoskeletal care at the Arthur Ashe Student Health and Wellness Center

SPORTS MEDICINE

The Division of Non-Operative Sports Medicine continues to be active in advancing clinical care both the office as well as on the sidelines with the UCLA Bruins In addition the Division conducts important research and members of the faculty hold national leadership positions The Division has also been active in using musculoskeletal ultrasound at the point of care for office-based procedures and diagnosis Division Chief John DiFiori MD recently served as Co-Director of the very successful UCLA Musculoskeletal Ultrasound Course which featured a cadaver lab for procedural training In the research arena Dr DiFiori is participating in a multicenter study on the long-term effects of sport-related concussion that was recently funded by the NCAA Aurelia Nattiv MD Director of the Osteoporosis Center recently published a five-year study on restoration of normal menses in college athletes with menstrual

SPORTS MEDICINENON-OPERATIVE ORTHOPAEDICS

14

disturbances Heather Gillespie MD MPH Director of the Pediatric Sports Medicine Service at Orthopaedic Hospital has recently completed research examining sports-related injuries presenting to an inner city underserved population Daniel Vigil MD joins the faculty in March from Kaiser Los Angeles The UCLA primary care sports medicine fellowship program attracts outstanding applicants from across the country

Though the AO technique was brought to UCLA in 1978 by Dr Tony Headly it was Eric Johnson MD FRCSI (Hon) (UCLA residency class of 1981) who

established the orthopaedic trauma program in 1982 Dr Johnson is the Division Chief and he specializes in orthopaedic traumatology and fracture surgery He serves as a Member of the Board of Directors of the AO Foundation and was awarded an Honorary Fellowship in the Royal College of Surgeons in Ireland on July 13 2009 Dublin Ireland (pictured above) In 2011 Dr Johnson was the guest of honor at the 23rd at the Letournel Pelvic and Acetabular Fracture Course in Paris France In September 2011 he gave the Keynote Lecture 30 Years of Acetabular Fracture Surgery and traveled to Ireland in November 2011 to give four lectures at the 10th Current Controversies in Trauma Management Royal College of Surgeons Dr Johnson continues to travel lecture and teach as part of his commitment to the AO Foundation

TRAUMA SURGERY

Devon Jeffcoat MD (UCLA resident class of 2009) joined the faculty at UCLA in 2010 after completing his fellowship at the Hospital for Special Surgery in New York under the tutelage of Dr David Helfet Dr Jeffcoat volunteered his time during the earthquake crisis in Haiti He has already developed a busy trauma surgery practice and became a mainstay for orthopaedics at the Westwood campusrsquo Level I trauma center Ronald Reagan-UCLA Medical Center Eric D Farrell MD joined the UCLA orthopaedic trauma staff in August 2011 He previously spent more than six years as Assistant Director of Orthopaedic Trauma at Cooper University Hospital in Camden NJ His training consisted of a trauma fellowship at Harborview Medical Center in Seattle WA AO Fellowship in Salzburg Austria and an Ilizarov Fellowship in Lecco Italy He has a particular interest in nonunions and deformity correction

15

ORTHOPAEDIC RESEARCH

In 2011 Orthopaedic Hospital celebrated its 100-year anniversary (see appended photos below of OH in 1917 and 2011) For the last two decades the century-old research mission at the Orthopaedic Hospital has flourished under the direction of Harry McKellop PhD and his discovery of orthopaedic device components with

greatly improved durability and longevity The standard for excellence in orthopaedic research at UCLA was set by Marshall Urist MD who discovered and ushered in the clinical use of bone morphogenetic protein to build back human bone where it was needed to make new bone for skeletal stability 1998 saw the alliance of the UCLA Department of Orthopaedic Surgery and Orthopaedic Hospital with a commitment to preserve the rich patient-oriented research mission embraced by both

HISTORICAL PERSPECTIVE

2007 witnessed the first step of the alliancersquos vision to expand the mission of the two institutions to become among the best orthopaedic research centers in the world with the opening of the Cesar Pelli-designed-Orthopaedic Hospital Research Center at the heart of the Court of Sciences on the UCLA Westwood campus (pictured on next page) As Director of the Orthopaedic Hospital Research Center John Adams MD (pictured below) was charged with realizing this expanded vision by mounting a bold recruiting effort to create an interschool (ie medicine engineering dentistry

etc) transdisciplinary

extramurally-funded bench-to-bedside team science approach to childhood and

adult musculoskeletal disease The recruitment effort culminated this spring with the addition of 22 new faculty members from around the world to laboratories in the Orthopaedic Hospital Research Center

RESEARCH BASIC SCIENCE AND TRANSLATIONAL

Highlights of this expansion from 2007 include 1) a 10-fold increase to $55M in annual peer-reviewed grant funding coming to the Department moving the Department to number seven on the list of the top NIH-granted departments in the country 2) the first ever NIH training grant in Orthopaedic Surgery for UCLA principled by John Adams MD and Karen Lyons PhD (pictured above) representing the only such training grant in orthopaedic surgery west of St Louis 3) the first ever large-scale grant ($56M total) from the California Institute for Regenerative Medicine for bone regeneration research principled by Chia Soo MD and Bruno Peault PhD and 4) presentation to the Department of Orthopaedic Surgery of an $82 million Clinical and Translational Science Award by the NIH the largest single grant to the David Geffen School of Medicine at UCLA None of these efforts would have been possible without advice

16

support and teamwork contributed by the Broad Stem Cell Institute the Jonsson Comprehensive Cancer Center the Department of Molecular Cell and Developmental Biology in the UCLA College of Letters and Science and the Clinical and Translational Science Institute

The Orthopaedic Hospital Research Center on the Westwood campus provides a fertile environment for our researchers

and clinicians to innovate and collaborate in pediatric orthopaedic science Karen Lyons PhD has received international awards for her breakthrough work in skeletal development and growth-plate biology while Deborah Krakow MD and Dan Cohn PhD (both pictured above) have identified several key genetic mutations that cause dwarfism These discoveries have lead to a better understanding of bone diseases that affect children and are the basis for novel future treatments Our clinicians and scientists are also focused on translational research that enhances orthopaedic treatment for children by improving surgical techniques and non-surgical care In collaboration with the pediatric spine surgeons Sophia Sangiorgio PhD and Edward Ebramzadeh PhD have developed an experimental model to test and compare surgical techniques used in scoliosis surgery Their work will be presented at this yearrsquos Scoliosis Research Society meeting Mauricio Silva MD maintains one of the largest prospective pediatric trauma registries in the country The analysis of this database has resulted in several recent JBJS publications that are likely to shape the evidence-based treatment of pediatric elbow fractures He and Fabrizio Billi PhD are also collaborating with scientists in UCLArsquos School of Engineering to develop a wireless technology that can improve the fit and function of casts used to treat childrenrsquos fractures In the field of motor disorders Eileen Fowler PhD PT (pictured) and

her team have recently developed and validated a method to measure selective motor control that can predict the success of surgery for patients with cerebral palsy We are proud of the

UCLAOrthopaedic Hospital partnership and the significant contributions our pediatric orthopaedic clinicians and scientists have made We look forward to further advances that help children overcome their musculoskeletal injuries and disease The Orthopaedic Hospital Research Center remains dedicated to its founding principles First that major advances in understanding the pathobiology and management of those diseases that are most frequently encountered by the practicing orthopaedic surgeon (eg fractures joint instability etc) can be best achieved by teams of scientists with expertise ranging from molecular biology to clinical care of patients Second understanding the developmental events that shape formation of the musculoskeletal system from fetal to adult life will inform us about the deconstruction of the system that happens with aging and disease Third that development of mouse models of common human orthopaedic disease where genes in the mouse can be ldquoknocked outrdquo or amplified will allow us to develop ldquopersonalized-rdquo molecularly-targeted preventative and treatment regimens Finally by bringing the cadre of clinician-scientists into a

17

common practice setting in the new Orthopaedic Hospital in at the Santa Monica-UCLA Medical Center and Orthopaedic Hospital we hope to translate basic discoveries made in the Orthopaedic Hospital Research Center to a new standard of orthopaedic health care for both children and adults

Another study is focusing on bone formation as well as spinal fusion We are utilizing bone graft substitutes along with the appropriate growth factors to optimize the healing of the spinal fusions through the least amount of invasiveness with minimally invasive techniques Our previous studies have shown that with gene therapy we have been able to achieve spinal fusion in a very efficient manner We hope to optimize this with

the use of new bone graft materials with new growth factors in order to obtain 100 spinal fusion ultimately for our patients We hope to start clinical trials in this soon Another study we are looking at is the suppression of tumors One of the growth factors that we have invented in our laboratory here at UCLA has shown an effect to inhibit BMP bone morphogenic growth factors many tumors rely on to grow We have shown the addition of this novel growth factor can suppress the growth of tumor cells We have initiated a project where we are attempting to use this novel protein to inhibit the growth of tumors We ultimately hope that this will act as a new therapeutic method in the fight against cancer A new technology of dynamic MRI imaging will allow us to identify the pathology for patients with spine problems We have previously published over 18 scientific articles looking at the effect of dynamic motion MRI in identifying spinal pathology We are perfecting this technique and hope to institute this as a part of our standard treatment protocol for patients with spinal problems

RESEARCH THE UCLA SPINE PROGRAM The Spine Service continues to explore new areas in both basic science and clinical research in the area of spinal disorders We have a world-class laboratory that continues to attract surgeons on an international level to come and participate in our research efforts We have seven ongoing international fellowships for surgeons to come and collaborate on our research projects One of our publications was named the outstanding paper award this past year by The Spine Journal We recently received an OREF (Orthopaedic Research and Education Foundation) grant for starting a biologics registry for spinal fusion Our basic science efforts encompass several novel projects for regeneration of the spinal tissuesdiscs We are utilizing the most novel gene therapy transfer techniques along with pleuripotent stem cells in order to regenerate the disc Through our previous work of injecting growth factors into disc we have been able to generate these discs in our prior studies We are trying to optimize this effect with the addition of stem cell technology to optimize the number of cells the concentration of growth factors as well as the optimal gene transfer in order to perfect the best technique to regenerate the disc We hope that this will soon move from the animal models into human trials

The Division of Sports Medicine continues to be productive in a number of research areas Our orthopaedic biomechanics lab has expanded with the addition of Daniel Boguszewski PhD Dr Boguszewski obtained his PhD from the University of Cincinnati where he developed expertise with a sophisticated robotic testing apparatus We recently acquired an industrial robot (pictured on next page) for mechanical testing and are looking forward to coupling this exciting new technique with existing techniques pioneered by Keith Markolf PhD Our bioengineers along with Drs David McAllister and Frank Petrigliano have formed a new collaboration with the UCLA Electrical Engineering Department Wireless Health initiative to develop novel ways to measure knee biomechanics and knee injury mechanisms in patients Drs McAllister and Petrigliano have established a lab at the Greater Los Angeles VA Medical Center and continue to collaborate with Ben Wu DDS PhD in the Department of

RESEARCH THE UCLA SPORTS MEDICINE PROGRAM

18

Bioengineering and Patricia Zuk PhD in the Department of Plastic Surgery on tissue engineering for ACL reconstruction and rotator cuff repair Drs Sharon Hame and David McAllister continue to participate in clinical research including outcomes of ACL reconstruction Both are co-investigators in the NIH-funded multicenter ACL Revision Surgery (MARS) study Both also continue to collect and analyze data on primary ACL reconstruction Drs Hame McAllister Gamradt and Petrigliano have all recently completed studies on the incidence of shoulder and knee procedures using the Peardiver database

19

Jeffrey Eckardt MD Professor and Chair Orthopaedic Surgery UCLA

Anthony Scaduto MD Executive Vice Chair and President and CAO LAOH

Jeffrey Wang MD Vice Chair of Clinical Operations Orthopaedic Surgery UCLA

John Adams MD Vice Chair of Research Orthopaedic Surgery UCLA

James Luck MD Residency Program Director Orthopaedic Surgery UCLAOH

FACULTY There are presently 73 faculty members in our Department of Orthopaedic Surgery

Foot and Ankle Surgery Andrea Cracchiolo III MD (Emeritus) Nelson SooHoo MD (Division Chief) Lewis Zionts MD

General Orthopaedics Peter Alexakis MD Bruce Brown MD PhD S Andrew Schwartz MD

Hand Surgery Kodi Azari MD Prosper Benhaim MD (Division Chief) Scott Mitchell MD

Joint Replacement Benjamin Bengs MD Bruce Brown MD PhD Francis Cyran MD Gerald Finerman MD Eric Johnson MD James Luck MD Bert Thomas MD (Division Chief)

Musculoskeletal Oncology Susan Bukata MD Francis Cyran MD Jeffrey Eckardt MD (Division Chief)

Osteoporosis John Adams MD Susan Bukata MD Aurelia Nattiv MD

Pediatric OrthopaedicsOrthopaedic Hospital Richard Bowen MD James Luck MD William Oppenheim MD Anthony Scaduto MD (Division Chief) Mauricio Silva MD Lewis Zionts MD

Spine SurgeryPMampR Richard Bowen MD Michael Daubs MD David Fish MD MPH (PMampR) Jae Jung MD (PMampR) Anthony Scaduto MD A Nick Shamie MD Jeffrey Wang MD (Division Chief)

Sports Medicine Richard Bowen MD Gerald Finerman MD Sharon Hame MD David McAllister MD (Division Chief) Robert Pedowitz MD PhD

Frank Petrigliano MD

Sports Medicine amp Non-Operative Orthopaedics John DiFiori MD (Division Chief) Heather Gillespie MD MPH Aurelia Nattiv MD Daniel Vigil MD

Trauma Surgery Benjamin Bengs MD Eric Farrell MD Devon Jeffcoat MD Eric Johnson MD (Division Chief)

Shriners Hospital Katherine Au MD Robert Cho MD Anna Cuomo MD Kathryn Doughty MD Colin Mosely MD Kit Song MD (Service Chief) Hugh Watts MD

VA Hospital Bruce Brown MD PhD Francis Cyran MD Sharon Hame MD Eric Johnson MD David McAllister MD Scott Mitchell MD Frank Petrigliano MD Nelson SooHoo MD (Service Chief) Bert Thomas MD Steven Zeitzew MD

Research Faculty John Adams MD (Vice Chair of Research) Maria-Grazia Ascenzi PhD Paul Bajaj PhD Fabrizio Billi PhD Daniel Boguszewski PhD Patricia Campbell PhD Daniel Cohn PhD Gay Crooks PhD Edward Ebramzadeh PhD Denis Evseenko MD PhD Eileen Fowler PhD PT Martin Hewison PhD Luisa Iruela-Arispe PhD Deborah Krakow MD Susan Krum PhD Timothy Lane PhD Philip Liu PhD Daniel Lu MD PhD Zhen Lu PhD Karen Lyons PhD Keith Markolf PhD Harry McKellop PhD Shen Pang PhD Sang-Hyun Park PhD Bruno Peault PhD Sophia Sangiorgio PhD Fu Wen Shen PhD B Chia Soo MD Kang Ting DMD Howard Winet PhD Benjamin Wu DDS PhD

20

RECENT FACULTY HONORS AND PUBLICATIONS John Adams MD

1 Vitamin D 3rd Edition Feldman DR Pike JW Adams JS eds San Diego Elsevier Press 2011

2 Chen H Gilbert LC Lu X Liu Z You S Weitzmann MN Nanes MS Adams JS Estrogen response element binding protein stimulates osteoclastogenesis and bone resorption J Bone Min Res 262537-2547 2011 PMCID PMC3417837

3 Fabri M Stenger S Shin D Yuk J Liu PT Realegeno S Lee H Krutzik SR Schenk M Sieling PA Teles R Montoya D Iyer SS Bruns H Lewinsohn DM Hollis BW Hewison M Adams JS Steinmeyer A Zuumlgel U Cheng G Jo E Bloom BR Modlin RL Vitamin D is required for IFN-γ mediated antimicrobial activity of human macrophages Sci Transl Med 3104ra102 2011 PMCID PMC3269210

4 Billi F Benya B Kavanaugh A Adams JS Ebramzadeh E McKellop H The John Charnley Award An accurate and extremely sensitive method to separate display and characterize wear debris part 1ndashpolythylene particles Clin Orthopaed Rel Res 470329-338 2012 PMCID PMC 3254734

5 James AW Pang S Askarinam A Corselli M Zara JN Goyal R Chang L Pan A Shen J Yuan W Stoker D Zhang X Adams JS Ting K Soo C Additive effects of sonic hedgehog and Nell-1 signaling in osteogenic versus adipogenic differentiation of human adipose-derived stromal cells Stem Cells Dev 212170-2178 2012 PMCID PMC3411358

Kodi Azari MD 1 Azari K Imbriglia JE Goitz RJ Shores JT Balk ML

Brandacher G Schneeberger S Gorantla V Lee WPldquoHandTransplantion The Donor and Operationrdquo Journal of Reconstructive Microsurgery (2012) 28(1) 27-34

2 Sue McDiarmid and Kodi Azari ldquoDonor Related Issues in Hand Transplantaionrdquo Hand Clinics (2011) 274 545-54

3 Tristan L Hartzell Prosper Benhaim Joeseph E Imbriglia Jaimie Shores Robert J Goitz Marshall Balk Scott Mitchell Roee Rubinstein Vijay Gorantla Stephan Schneeberger Gerald Brandacher W P Andrew LeeKodi K Azari ldquoSurgical and Technical Aspects of Hand Transplantation ndash Is it Just Another Replantrdquo Hand Clinics (2011) 274 521-30

4 Immune Modulation for Hand Transplantation Changing the Risk-Benefit Balance Brandacher G Gorantla VS Schneeberger S Shores JT Imbriglia JE Azari K Donnenberg AD Cooney DS Losee JE Lee WPA J Healthcare Science Humanities 20111(4)62-68

5 Elaine Horibe Song Afshin Shirazian Brian

Binns Yuedi Fleming Lydia M Ferreira Rod J Rohrich Kodi Azari ldquoBenchmarking academic plastic surgery services in the USrdquo Plastic and Reconstructive Surgery (2012) 129(6)1407-18

Benjamin Bengs MD

1 Bengs BC Sangiorgio SN Ebramzadeh E Achieving Clinically Adequate Stem Fixation Despite Severe Proximal Femoral Bone Loss Poster P039 Orthopedic Research Society Annual Meeting San Fransisco CA 2012

2 Sangiorgio S Knutsen A Kalma J Ebramzadeh E Bengs B Can a Dual-tapered Press-fit Stem be used in Cases with Severe Proximal Femoral Defects AAOS Poster 2043 Annual Meeting in San Francisco CA

3 Sugi M Sheridan K Lewis L Huang MH Nattiv A Kado DM BC Bengs Active referral intervention following fragility fractures leads to enhanced osteoporosis follow-up carerdquo Journal of Osteoporosis (accepted 2012)

4 Sangiorgio S Ebramzadeh E Knutsen A Kalma J Bengs B Can a Dual-tapered Press-fit Stem be used in Cases with Severe Proximal Femoral Defects Journal of Biomaterials and Biomechanics (accepted 2012)

5 Aaron W James Jia Shen Xinli Zhang Michael Chiang Asal Askarinam Raghav Goyal Alan Nguyen Janette N Zara Greg Asatrian Jonguk Chung Benjamin Bengs Cymbeline T Culiat A Simon Turner Howard B Seim III John S Adams Kang Ting Chia Soo Nell-1 Regulates Osteoblast Osteoclast Activity and Activates Wntβ-catenin Signaling A New Cause and Treatment for Osteoporosis (submitted for publication)

Prosper Benhaim MD 1 Benhaim P Anthony JP Lin LYT McCalmont TH

Mathes SJ A long-term study of allogeneic rat hindlimb transplants immunosuppressed with RS-61443 Transplantation 1993 56(4) 911-917

2 Tejwani SG Markolf KL Benhaim P Graft reconstruction of the interosseous membrane in conjunction with metallic radial head replacement a cadaveric study Journal of Hand Surgery 2005 30A(2) 335-342

3 Markolf KL Tejwani SG Benhaim P Effects of wafer resection and hemiresection from the distal ulna on load-sharing at the wrist a cadaveric study Journal of Bone and Joint Surgery 2005 30A(2) 351-358

4 Dragoo JL Lieberman JR Lee RS DeUgarte DA Lee Y Zuk PA Hedrick MH Benhaim P ldquoTissue engineered bone from BMP-2 transduced stem cells derived from human fat Plastic and Reconstructive Surgery 2005 115(6) 1665-1673

21

5 Dragoo JL Carlson G McCormick F Khan-Farooqi H Zhu M Zuk PA Benhaim P Healing full-thickness cartilage defects using adipose-derived stem cells Tissue Engineering 2007 13(7) 1615-1621

Nicholas Bernthal MD

1 Kremen TJ Jr Bernthal NM Eckardt MA Eckardt JJ Giant cell tumor of bone are we stratifying results appropriately Clin Orthop Relat Res 2012 Mar470(3)677-83

2 Bernthal NM Federman N Eilber FR Nelson SD Eckardt JJ Eilber FC Tap WD Long-term results (gt25 years) of a randomized prospective clinical trial evaluating chemotherapy in patients with high-grade operable osteosarcoma Cancer 2012 Dec 1118(23)5888-93 doi 101002cncr27651 Epub 2012 May 30

3 Pribaz JR Bernthal NM Wong TC Silva M Lateral spurring (overgrowth) after pediatric lateral condyle fractures J Pediatr Orthop 2012 Jul-Aug32(5)456-60

4 Silva M Knutsen AR Kalma JJ Borkowski SL Bernthal NM Spencer HT Sangiorgio SN Ebramzadeh E Biomechanical Testing of Pin Configurations in Supracondylar Humeral Fractures The Effect of Medial Column Comminution J Orthop Trauma 2012 Aug 28 [Epub ahead of print]

5 Niska JA Meganck JA Pribaz JR Shahbazian JH Lim E Zhang N Rice BW Akin A Ramos RI Bernthal NM Francis KP Miller LS Monitoring bacterial burden inflammation and bone damage longitudinally using optical and μCT imaging in an orthopaedic implant infection in mice PLoS One 20127(10)e47397 doi 101371journalpone0047397 Epub 2012 Oct 17

Rick Bowen MD

1 POSNA Traveling Fellowship Recipient (2008) 2 Bowen RE Scaduto AA Banuelos S Does early

thoracic fusion exacerbate preexisting restrictive lung disease in congenital scoliosis patients J Pediatr Orthop 28 506-511 2008

3 Bowen RE Scaduto AA Banuelos S Decreased body mass index and restrictive lung disease in congenital thoracic scoliosis J Pediatr Orthop 28665-8 2008

4 Bowen RE Gardner S Scaduto AA Eagan M Beckstead J Efficacy of intraoperative cell salvage systems in pediatric idiopathic scoliosis patients undergoing posterior spinal fusion with segmental spinal instrumentationSpine (Phila Pa 1976) 35246-51 2010

5 Bowen RE Knee injuries in the youth athlete Curr Orthop Prac 2012 23 422-428

Susan Bukata MD 1 Houck J Kneiss J Bukata SV Puzas JE Analysis of

vertical ground reaction force variables during a Sit to Stand task in participants recovering from a hip fracture Clin Biomech 2011 Jun 26(5) 470-6

2 Takahata M Awad HA OrsquoKeefe RJ Bukata SV Schwarz EM Endogenous tissue engineering PTH therapy for skeletal repair Cell Tissue Res 2011 May 31 [Epub ahead of print]

3 Kates SL Bukata SV DiGiovanni BF Friedman SL et al A guide to improving the care of patients with fragility fractures Geriatric Orthopaedic Surgery amp Rehabilitation 2011 2(1) 5-37

4 Sampson ER Chen D Schwarz EM Bukata SV OrsquoKeefe RJ Awad H Puzas JE Zuscik MJ Rosier RN Teriparatide as a chondro-regenerative therapy for injury-induced knee osteoarthritis Science Translational Medicine 2011 Sept 21 3(101) 101ra93

5 Kneiss JA Houck JR Bukata SV Puzas JE Influence of Upper Extremity Assistance on Lower Extremity Force Application Symmetry in Individuals Post-Hip Fracture During the Sit-to-Stand Task Journal of Orthopaedic amp Sports Physical Therapy 2012 May 42(5) 474-481

Michael Daubs MD

1 Patton CM Hung M Lawrence BD Patel A Woodbury AM Brodke DS Daubs MD Psychological Distress in a Department of Veteransrsquo Affairs Spine Patient Population The Spine J 2011 Nov 15 (epub ahead of print)

2 Daubs MD Lenke LG Kim YJ Cheh G Stobbs G Bridwell KH Does Correction of Preoperative Coronal Imbalance Make a Difference in Outcomes of Adult Deformity Patients Accepted for publication Spine June 2012

3 Daubs MD Patel AA Lawrence BD Brodke DS Excision of the Posterior Longitudinal Ligament During Anterior Cervical Corpectomy A Biomechanical Study Accepted for publication September 12 2012J Spinal Disorders

4 Daubs MD Lenke LG Cheh G Bridwell KH Kim YJ Stobbs G Decompression Alone Versus Decompression with Limited Fusion for the Treatment of Degenerative Lumbar Scoliosis in the Elderly Patient Accepted for publication Sept 5 2012Evidence Based Spine Journal

5 Tan Y Montgomery SR Aghdasi BG Inoue H Kaner T Tian H Terrell R Zhang X Wang JC Daubs MD The Effect of Corticosteroid Administration on Soft Tissue Inflammation Associated with rhBMP-2 use in a Rodent Model of Inflammation Spine (Phila Pa 1976) 2012 Nov 28 [Epub ahead of print]

12

Health (NIH) assessing risk factors for osteoporotic fracture in older women (the Leisure World Cohort Study) as well as studies evaluating optimal referral interventions for post-fracture patients Additional members of the metabolic bone team include Dr Adams in addition to Susan Bukata MD Benjamin Bengs MD and Freda Hannafon FNP-C The Center provides comprehensive care for patients with osteoporosis including diagnosis and treatment The metabolic bone team includes physicians in the fields of endocrinology geriatrics sports medicine and orthopaedic surgery The team works closely with the patientrsquos own referring physician to optimize bone health and prevent future fractures When referring patients to the Center physicians can request only a DXA for accurate assessment of bone health or refer patients for complete evaluation and consultation with UCLArsquos team of experts for interpretation of test results and recommendations for fracture prevention In addition to working closely with the patientrsquos primary care physician the comprehensive team will often include a physical therapist who specializes in balance and fall prevention occupational therapists who help patients with the activities of daily life and dietitians who provide guidance in nutrition The metabolic bone team has also worked closely with the UCLA Faculty Practice Group to alert physicians of their patients who have had low impact fragility fractures in the efforts to facilitate diagnosis and treatment of osteoporosis in a university-wide fracture protocol program and adherence to osteoporosis-related metrics John S Adams MD is an endocrinologist and internationally-recognized expert in vitamin D and an authority in the hormones that control skeletal homeostasis He is Vice Chair of Research in the UCLA-Orthopaedic Hospital Research Center (OHRC) and Associate Director of the newly minted NIH-funded Clinical and Translational Science Institute at UCLA Dr Adams is a renowned

clinician-scientist being continuously funded for the last 32 years by the NIH for both basic science and clinical research He currently serves as an Associate Editor for the Journal of Bone and Mineral Research and as a member of the Council of the American Society for Bone and Mineral Research Susan Bukata MD Associate Professor of Orthopaedic Surgery is an orthopaedic surgeon and new addition to the Department in 2012 Dr Bukata specializes in metabolic bone disease and orthopaedic oncology She helped develop the geriatric fracture center algorithm from the University of Rochester that has become the best practices standard for inpatient fragility fracture care She is a translational research specialist working with agents that stimulate and modulate fracture healing including teriparatide Her clinical practice in metabolic bone diseases includes not only osteoporosis patients but also children and adults with fragility fracture problems associated with genetic and developmental diseases such as osteogenesis imperfecta cerebral palsy and the muscular dystrophies She cares for patients of all ages including many patients who do not fit standard care algorithms

The pediatric orthopaedic program was started in 1979 by William Oppenheim MD (pictured) who also founded the Center for Cerebral Palsy in 1995 Dr Oppenheim recently joined Los Angeles Orthopaedic Hospital which has been associated with UCLA since 1996 as part of the alliance

agreement The subspecialty pediatric clinics at the downtown campus of LAOH are some of the busiest in the country with over 55000 pediatric orthopaedic visits last year Families from around the region seek out our facultyrsquos expertise in cerebral palsy (Dr Oppenheim) clubfoot (Lewis Zionts MD) sports medicine (Heather Gillespie

PEDIATRIC ORTHOPAEDICS

13

MD MPH and Richard Bowen MD UCLA residency class of 2001) trauma (Mauricio Silva MD) tumor (Francis Cyran MD) and scoliosis (Richard Bowen MD and Anthony Scaduto MD UCLA residency class of 2002) Our multidisciplinary clinics offer unique comprehensive care for spina bifida muscle disease osteogenesis imperfecta hemophilia and limb deficiencyamputation A skeletal dysplasia clinic is due to open this year (Pictured from left to right Oppenheim Zionts Scaduto Bowen Silva)

The Division of Sports Medicine was founded in 1971 by Gerald Finerman MD (pictured) Dr Finerman has been on the UCLA faculty since then and was the former Department Chair from 1996-2009 He will join the Emeritus faculty in July 2013 and continue his involvement with medical student resident and fellow teaching The Division is now led by David McAllister MD Division Chief and Program Director of the Sports Medicine Fellowship Program Additional sports medicine faculty members include Sharon Hame MD Professor who has a special interest in hip arthroscopy and works part-time at the West Los Angeles VA Professor Robert Pedowitz MD PhD was Department Chair from 2009-2010 and specializes in shoulder and knee surgery and research in arthroscopic simulation Frank

Petrigliano MD Assistant Professor and UCLA resident class of 2009 focuses his clinical and research activity in shoulder surgery and sports medicine Dr Petrigliano studies the basic science of rotator cuff disease at UCLA is clinical faculty at both the VA and Olive View Medical Center As of March 1st 2013 Seth Gamradt MD (UCLA resident class of 2006) will join the USC faculty as Associate Professor and Director of Orthopaedic Athletic Medicine for USC Athletics Dr Gamradt is a specialist in shoulder surgery and sports medicine with interests in shoulder replacement and knee ligament reconstruction Still a friend in spite of his ldquodefectionrdquo we wish him the best of luck and appreciate this unique opportunity for him The sports medicine faculty members see patients at both the Westwood and Santa Monica campuses These physicians serve as the exclusive provider of medical services to the UCLA Athletic Department They continue to provide care for more than 700 UCLA intercollegiate athletes at the Acosta Athletic Training Complex and provide musculoskeletal care at the Arthur Ashe Student Health and Wellness Center

SPORTS MEDICINE

The Division of Non-Operative Sports Medicine continues to be active in advancing clinical care both the office as well as on the sidelines with the UCLA Bruins In addition the Division conducts important research and members of the faculty hold national leadership positions The Division has also been active in using musculoskeletal ultrasound at the point of care for office-based procedures and diagnosis Division Chief John DiFiori MD recently served as Co-Director of the very successful UCLA Musculoskeletal Ultrasound Course which featured a cadaver lab for procedural training In the research arena Dr DiFiori is participating in a multicenter study on the long-term effects of sport-related concussion that was recently funded by the NCAA Aurelia Nattiv MD Director of the Osteoporosis Center recently published a five-year study on restoration of normal menses in college athletes with menstrual

SPORTS MEDICINENON-OPERATIVE ORTHOPAEDICS

14

disturbances Heather Gillespie MD MPH Director of the Pediatric Sports Medicine Service at Orthopaedic Hospital has recently completed research examining sports-related injuries presenting to an inner city underserved population Daniel Vigil MD joins the faculty in March from Kaiser Los Angeles The UCLA primary care sports medicine fellowship program attracts outstanding applicants from across the country

Though the AO technique was brought to UCLA in 1978 by Dr Tony Headly it was Eric Johnson MD FRCSI (Hon) (UCLA residency class of 1981) who

established the orthopaedic trauma program in 1982 Dr Johnson is the Division Chief and he specializes in orthopaedic traumatology and fracture surgery He serves as a Member of the Board of Directors of the AO Foundation and was awarded an Honorary Fellowship in the Royal College of Surgeons in Ireland on July 13 2009 Dublin Ireland (pictured above) In 2011 Dr Johnson was the guest of honor at the 23rd at the Letournel Pelvic and Acetabular Fracture Course in Paris France In September 2011 he gave the Keynote Lecture 30 Years of Acetabular Fracture Surgery and traveled to Ireland in November 2011 to give four lectures at the 10th Current Controversies in Trauma Management Royal College of Surgeons Dr Johnson continues to travel lecture and teach as part of his commitment to the AO Foundation

TRAUMA SURGERY

Devon Jeffcoat MD (UCLA resident class of 2009) joined the faculty at UCLA in 2010 after completing his fellowship at the Hospital for Special Surgery in New York under the tutelage of Dr David Helfet Dr Jeffcoat volunteered his time during the earthquake crisis in Haiti He has already developed a busy trauma surgery practice and became a mainstay for orthopaedics at the Westwood campusrsquo Level I trauma center Ronald Reagan-UCLA Medical Center Eric D Farrell MD joined the UCLA orthopaedic trauma staff in August 2011 He previously spent more than six years as Assistant Director of Orthopaedic Trauma at Cooper University Hospital in Camden NJ His training consisted of a trauma fellowship at Harborview Medical Center in Seattle WA AO Fellowship in Salzburg Austria and an Ilizarov Fellowship in Lecco Italy He has a particular interest in nonunions and deformity correction

15

ORTHOPAEDIC RESEARCH

In 2011 Orthopaedic Hospital celebrated its 100-year anniversary (see appended photos below of OH in 1917 and 2011) For the last two decades the century-old research mission at the Orthopaedic Hospital has flourished under the direction of Harry McKellop PhD and his discovery of orthopaedic device components with

greatly improved durability and longevity The standard for excellence in orthopaedic research at UCLA was set by Marshall Urist MD who discovered and ushered in the clinical use of bone morphogenetic protein to build back human bone where it was needed to make new bone for skeletal stability 1998 saw the alliance of the UCLA Department of Orthopaedic Surgery and Orthopaedic Hospital with a commitment to preserve the rich patient-oriented research mission embraced by both

HISTORICAL PERSPECTIVE

2007 witnessed the first step of the alliancersquos vision to expand the mission of the two institutions to become among the best orthopaedic research centers in the world with the opening of the Cesar Pelli-designed-Orthopaedic Hospital Research Center at the heart of the Court of Sciences on the UCLA Westwood campus (pictured on next page) As Director of the Orthopaedic Hospital Research Center John Adams MD (pictured below) was charged with realizing this expanded vision by mounting a bold recruiting effort to create an interschool (ie medicine engineering dentistry

etc) transdisciplinary

extramurally-funded bench-to-bedside team science approach to childhood and

adult musculoskeletal disease The recruitment effort culminated this spring with the addition of 22 new faculty members from around the world to laboratories in the Orthopaedic Hospital Research Center

RESEARCH BASIC SCIENCE AND TRANSLATIONAL

Highlights of this expansion from 2007 include 1) a 10-fold increase to $55M in annual peer-reviewed grant funding coming to the Department moving the Department to number seven on the list of the top NIH-granted departments in the country 2) the first ever NIH training grant in Orthopaedic Surgery for UCLA principled by John Adams MD and Karen Lyons PhD (pictured above) representing the only such training grant in orthopaedic surgery west of St Louis 3) the first ever large-scale grant ($56M total) from the California Institute for Regenerative Medicine for bone regeneration research principled by Chia Soo MD and Bruno Peault PhD and 4) presentation to the Department of Orthopaedic Surgery of an $82 million Clinical and Translational Science Award by the NIH the largest single grant to the David Geffen School of Medicine at UCLA None of these efforts would have been possible without advice

16

support and teamwork contributed by the Broad Stem Cell Institute the Jonsson Comprehensive Cancer Center the Department of Molecular Cell and Developmental Biology in the UCLA College of Letters and Science and the Clinical and Translational Science Institute

The Orthopaedic Hospital Research Center on the Westwood campus provides a fertile environment for our researchers

and clinicians to innovate and collaborate in pediatric orthopaedic science Karen Lyons PhD has received international awards for her breakthrough work in skeletal development and growth-plate biology while Deborah Krakow MD and Dan Cohn PhD (both pictured above) have identified several key genetic mutations that cause dwarfism These discoveries have lead to a better understanding of bone diseases that affect children and are the basis for novel future treatments Our clinicians and scientists are also focused on translational research that enhances orthopaedic treatment for children by improving surgical techniques and non-surgical care In collaboration with the pediatric spine surgeons Sophia Sangiorgio PhD and Edward Ebramzadeh PhD have developed an experimental model to test and compare surgical techniques used in scoliosis surgery Their work will be presented at this yearrsquos Scoliosis Research Society meeting Mauricio Silva MD maintains one of the largest prospective pediatric trauma registries in the country The analysis of this database has resulted in several recent JBJS publications that are likely to shape the evidence-based treatment of pediatric elbow fractures He and Fabrizio Billi PhD are also collaborating with scientists in UCLArsquos School of Engineering to develop a wireless technology that can improve the fit and function of casts used to treat childrenrsquos fractures In the field of motor disorders Eileen Fowler PhD PT (pictured) and

her team have recently developed and validated a method to measure selective motor control that can predict the success of surgery for patients with cerebral palsy We are proud of the

UCLAOrthopaedic Hospital partnership and the significant contributions our pediatric orthopaedic clinicians and scientists have made We look forward to further advances that help children overcome their musculoskeletal injuries and disease The Orthopaedic Hospital Research Center remains dedicated to its founding principles First that major advances in understanding the pathobiology and management of those diseases that are most frequently encountered by the practicing orthopaedic surgeon (eg fractures joint instability etc) can be best achieved by teams of scientists with expertise ranging from molecular biology to clinical care of patients Second understanding the developmental events that shape formation of the musculoskeletal system from fetal to adult life will inform us about the deconstruction of the system that happens with aging and disease Third that development of mouse models of common human orthopaedic disease where genes in the mouse can be ldquoknocked outrdquo or amplified will allow us to develop ldquopersonalized-rdquo molecularly-targeted preventative and treatment regimens Finally by bringing the cadre of clinician-scientists into a

17

common practice setting in the new Orthopaedic Hospital in at the Santa Monica-UCLA Medical Center and Orthopaedic Hospital we hope to translate basic discoveries made in the Orthopaedic Hospital Research Center to a new standard of orthopaedic health care for both children and adults

Another study is focusing on bone formation as well as spinal fusion We are utilizing bone graft substitutes along with the appropriate growth factors to optimize the healing of the spinal fusions through the least amount of invasiveness with minimally invasive techniques Our previous studies have shown that with gene therapy we have been able to achieve spinal fusion in a very efficient manner We hope to optimize this with

the use of new bone graft materials with new growth factors in order to obtain 100 spinal fusion ultimately for our patients We hope to start clinical trials in this soon Another study we are looking at is the suppression of tumors One of the growth factors that we have invented in our laboratory here at UCLA has shown an effect to inhibit BMP bone morphogenic growth factors many tumors rely on to grow We have shown the addition of this novel growth factor can suppress the growth of tumor cells We have initiated a project where we are attempting to use this novel protein to inhibit the growth of tumors We ultimately hope that this will act as a new therapeutic method in the fight against cancer A new technology of dynamic MRI imaging will allow us to identify the pathology for patients with spine problems We have previously published over 18 scientific articles looking at the effect of dynamic motion MRI in identifying spinal pathology We are perfecting this technique and hope to institute this as a part of our standard treatment protocol for patients with spinal problems

RESEARCH THE UCLA SPINE PROGRAM The Spine Service continues to explore new areas in both basic science and clinical research in the area of spinal disorders We have a world-class laboratory that continues to attract surgeons on an international level to come and participate in our research efforts We have seven ongoing international fellowships for surgeons to come and collaborate on our research projects One of our publications was named the outstanding paper award this past year by The Spine Journal We recently received an OREF (Orthopaedic Research and Education Foundation) grant for starting a biologics registry for spinal fusion Our basic science efforts encompass several novel projects for regeneration of the spinal tissuesdiscs We are utilizing the most novel gene therapy transfer techniques along with pleuripotent stem cells in order to regenerate the disc Through our previous work of injecting growth factors into disc we have been able to generate these discs in our prior studies We are trying to optimize this effect with the addition of stem cell technology to optimize the number of cells the concentration of growth factors as well as the optimal gene transfer in order to perfect the best technique to regenerate the disc We hope that this will soon move from the animal models into human trials

The Division of Sports Medicine continues to be productive in a number of research areas Our orthopaedic biomechanics lab has expanded with the addition of Daniel Boguszewski PhD Dr Boguszewski obtained his PhD from the University of Cincinnati where he developed expertise with a sophisticated robotic testing apparatus We recently acquired an industrial robot (pictured on next page) for mechanical testing and are looking forward to coupling this exciting new technique with existing techniques pioneered by Keith Markolf PhD Our bioengineers along with Drs David McAllister and Frank Petrigliano have formed a new collaboration with the UCLA Electrical Engineering Department Wireless Health initiative to develop novel ways to measure knee biomechanics and knee injury mechanisms in patients Drs McAllister and Petrigliano have established a lab at the Greater Los Angeles VA Medical Center and continue to collaborate with Ben Wu DDS PhD in the Department of

RESEARCH THE UCLA SPORTS MEDICINE PROGRAM

18

Bioengineering and Patricia Zuk PhD in the Department of Plastic Surgery on tissue engineering for ACL reconstruction and rotator cuff repair Drs Sharon Hame and David McAllister continue to participate in clinical research including outcomes of ACL reconstruction Both are co-investigators in the NIH-funded multicenter ACL Revision Surgery (MARS) study Both also continue to collect and analyze data on primary ACL reconstruction Drs Hame McAllister Gamradt and Petrigliano have all recently completed studies on the incidence of shoulder and knee procedures using the Peardiver database

19

Jeffrey Eckardt MD Professor and Chair Orthopaedic Surgery UCLA

Anthony Scaduto MD Executive Vice Chair and President and CAO LAOH

Jeffrey Wang MD Vice Chair of Clinical Operations Orthopaedic Surgery UCLA

John Adams MD Vice Chair of Research Orthopaedic Surgery UCLA

James Luck MD Residency Program Director Orthopaedic Surgery UCLAOH

FACULTY There are presently 73 faculty members in our Department of Orthopaedic Surgery

Foot and Ankle Surgery Andrea Cracchiolo III MD (Emeritus) Nelson SooHoo MD (Division Chief) Lewis Zionts MD

General Orthopaedics Peter Alexakis MD Bruce Brown MD PhD S Andrew Schwartz MD

Hand Surgery Kodi Azari MD Prosper Benhaim MD (Division Chief) Scott Mitchell MD

Joint Replacement Benjamin Bengs MD Bruce Brown MD PhD Francis Cyran MD Gerald Finerman MD Eric Johnson MD James Luck MD Bert Thomas MD (Division Chief)

Musculoskeletal Oncology Susan Bukata MD Francis Cyran MD Jeffrey Eckardt MD (Division Chief)

Osteoporosis John Adams MD Susan Bukata MD Aurelia Nattiv MD

Pediatric OrthopaedicsOrthopaedic Hospital Richard Bowen MD James Luck MD William Oppenheim MD Anthony Scaduto MD (Division Chief) Mauricio Silva MD Lewis Zionts MD

Spine SurgeryPMampR Richard Bowen MD Michael Daubs MD David Fish MD MPH (PMampR) Jae Jung MD (PMampR) Anthony Scaduto MD A Nick Shamie MD Jeffrey Wang MD (Division Chief)

Sports Medicine Richard Bowen MD Gerald Finerman MD Sharon Hame MD David McAllister MD (Division Chief) Robert Pedowitz MD PhD

Frank Petrigliano MD

Sports Medicine amp Non-Operative Orthopaedics John DiFiori MD (Division Chief) Heather Gillespie MD MPH Aurelia Nattiv MD Daniel Vigil MD

Trauma Surgery Benjamin Bengs MD Eric Farrell MD Devon Jeffcoat MD Eric Johnson MD (Division Chief)

Shriners Hospital Katherine Au MD Robert Cho MD Anna Cuomo MD Kathryn Doughty MD Colin Mosely MD Kit Song MD (Service Chief) Hugh Watts MD

VA Hospital Bruce Brown MD PhD Francis Cyran MD Sharon Hame MD Eric Johnson MD David McAllister MD Scott Mitchell MD Frank Petrigliano MD Nelson SooHoo MD (Service Chief) Bert Thomas MD Steven Zeitzew MD

Research Faculty John Adams MD (Vice Chair of Research) Maria-Grazia Ascenzi PhD Paul Bajaj PhD Fabrizio Billi PhD Daniel Boguszewski PhD Patricia Campbell PhD Daniel Cohn PhD Gay Crooks PhD Edward Ebramzadeh PhD Denis Evseenko MD PhD Eileen Fowler PhD PT Martin Hewison PhD Luisa Iruela-Arispe PhD Deborah Krakow MD Susan Krum PhD Timothy Lane PhD Philip Liu PhD Daniel Lu MD PhD Zhen Lu PhD Karen Lyons PhD Keith Markolf PhD Harry McKellop PhD Shen Pang PhD Sang-Hyun Park PhD Bruno Peault PhD Sophia Sangiorgio PhD Fu Wen Shen PhD B Chia Soo MD Kang Ting DMD Howard Winet PhD Benjamin Wu DDS PhD

20

RECENT FACULTY HONORS AND PUBLICATIONS John Adams MD

1 Vitamin D 3rd Edition Feldman DR Pike JW Adams JS eds San Diego Elsevier Press 2011

2 Chen H Gilbert LC Lu X Liu Z You S Weitzmann MN Nanes MS Adams JS Estrogen response element binding protein stimulates osteoclastogenesis and bone resorption J Bone Min Res 262537-2547 2011 PMCID PMC3417837

3 Fabri M Stenger S Shin D Yuk J Liu PT Realegeno S Lee H Krutzik SR Schenk M Sieling PA Teles R Montoya D Iyer SS Bruns H Lewinsohn DM Hollis BW Hewison M Adams JS Steinmeyer A Zuumlgel U Cheng G Jo E Bloom BR Modlin RL Vitamin D is required for IFN-γ mediated antimicrobial activity of human macrophages Sci Transl Med 3104ra102 2011 PMCID PMC3269210

4 Billi F Benya B Kavanaugh A Adams JS Ebramzadeh E McKellop H The John Charnley Award An accurate and extremely sensitive method to separate display and characterize wear debris part 1ndashpolythylene particles Clin Orthopaed Rel Res 470329-338 2012 PMCID PMC 3254734

5 James AW Pang S Askarinam A Corselli M Zara JN Goyal R Chang L Pan A Shen J Yuan W Stoker D Zhang X Adams JS Ting K Soo C Additive effects of sonic hedgehog and Nell-1 signaling in osteogenic versus adipogenic differentiation of human adipose-derived stromal cells Stem Cells Dev 212170-2178 2012 PMCID PMC3411358

Kodi Azari MD 1 Azari K Imbriglia JE Goitz RJ Shores JT Balk ML

Brandacher G Schneeberger S Gorantla V Lee WPldquoHandTransplantion The Donor and Operationrdquo Journal of Reconstructive Microsurgery (2012) 28(1) 27-34

2 Sue McDiarmid and Kodi Azari ldquoDonor Related Issues in Hand Transplantaionrdquo Hand Clinics (2011) 274 545-54

3 Tristan L Hartzell Prosper Benhaim Joeseph E Imbriglia Jaimie Shores Robert J Goitz Marshall Balk Scott Mitchell Roee Rubinstein Vijay Gorantla Stephan Schneeberger Gerald Brandacher W P Andrew LeeKodi K Azari ldquoSurgical and Technical Aspects of Hand Transplantation ndash Is it Just Another Replantrdquo Hand Clinics (2011) 274 521-30

4 Immune Modulation for Hand Transplantation Changing the Risk-Benefit Balance Brandacher G Gorantla VS Schneeberger S Shores JT Imbriglia JE Azari K Donnenberg AD Cooney DS Losee JE Lee WPA J Healthcare Science Humanities 20111(4)62-68

5 Elaine Horibe Song Afshin Shirazian Brian

Binns Yuedi Fleming Lydia M Ferreira Rod J Rohrich Kodi Azari ldquoBenchmarking academic plastic surgery services in the USrdquo Plastic and Reconstructive Surgery (2012) 129(6)1407-18

Benjamin Bengs MD

1 Bengs BC Sangiorgio SN Ebramzadeh E Achieving Clinically Adequate Stem Fixation Despite Severe Proximal Femoral Bone Loss Poster P039 Orthopedic Research Society Annual Meeting San Fransisco CA 2012

2 Sangiorgio S Knutsen A Kalma J Ebramzadeh E Bengs B Can a Dual-tapered Press-fit Stem be used in Cases with Severe Proximal Femoral Defects AAOS Poster 2043 Annual Meeting in San Francisco CA

3 Sugi M Sheridan K Lewis L Huang MH Nattiv A Kado DM BC Bengs Active referral intervention following fragility fractures leads to enhanced osteoporosis follow-up carerdquo Journal of Osteoporosis (accepted 2012)

4 Sangiorgio S Ebramzadeh E Knutsen A Kalma J Bengs B Can a Dual-tapered Press-fit Stem be used in Cases with Severe Proximal Femoral Defects Journal of Biomaterials and Biomechanics (accepted 2012)

5 Aaron W James Jia Shen Xinli Zhang Michael Chiang Asal Askarinam Raghav Goyal Alan Nguyen Janette N Zara Greg Asatrian Jonguk Chung Benjamin Bengs Cymbeline T Culiat A Simon Turner Howard B Seim III John S Adams Kang Ting Chia Soo Nell-1 Regulates Osteoblast Osteoclast Activity and Activates Wntβ-catenin Signaling A New Cause and Treatment for Osteoporosis (submitted for publication)

Prosper Benhaim MD 1 Benhaim P Anthony JP Lin LYT McCalmont TH

Mathes SJ A long-term study of allogeneic rat hindlimb transplants immunosuppressed with RS-61443 Transplantation 1993 56(4) 911-917

2 Tejwani SG Markolf KL Benhaim P Graft reconstruction of the interosseous membrane in conjunction with metallic radial head replacement a cadaveric study Journal of Hand Surgery 2005 30A(2) 335-342

3 Markolf KL Tejwani SG Benhaim P Effects of wafer resection and hemiresection from the distal ulna on load-sharing at the wrist a cadaveric study Journal of Bone and Joint Surgery 2005 30A(2) 351-358

4 Dragoo JL Lieberman JR Lee RS DeUgarte DA Lee Y Zuk PA Hedrick MH Benhaim P ldquoTissue engineered bone from BMP-2 transduced stem cells derived from human fat Plastic and Reconstructive Surgery 2005 115(6) 1665-1673

21

5 Dragoo JL Carlson G McCormick F Khan-Farooqi H Zhu M Zuk PA Benhaim P Healing full-thickness cartilage defects using adipose-derived stem cells Tissue Engineering 2007 13(7) 1615-1621

Nicholas Bernthal MD

1 Kremen TJ Jr Bernthal NM Eckardt MA Eckardt JJ Giant cell tumor of bone are we stratifying results appropriately Clin Orthop Relat Res 2012 Mar470(3)677-83

2 Bernthal NM Federman N Eilber FR Nelson SD Eckardt JJ Eilber FC Tap WD Long-term results (gt25 years) of a randomized prospective clinical trial evaluating chemotherapy in patients with high-grade operable osteosarcoma Cancer 2012 Dec 1118(23)5888-93 doi 101002cncr27651 Epub 2012 May 30

3 Pribaz JR Bernthal NM Wong TC Silva M Lateral spurring (overgrowth) after pediatric lateral condyle fractures J Pediatr Orthop 2012 Jul-Aug32(5)456-60

4 Silva M Knutsen AR Kalma JJ Borkowski SL Bernthal NM Spencer HT Sangiorgio SN Ebramzadeh E Biomechanical Testing of Pin Configurations in Supracondylar Humeral Fractures The Effect of Medial Column Comminution J Orthop Trauma 2012 Aug 28 [Epub ahead of print]

5 Niska JA Meganck JA Pribaz JR Shahbazian JH Lim E Zhang N Rice BW Akin A Ramos RI Bernthal NM Francis KP Miller LS Monitoring bacterial burden inflammation and bone damage longitudinally using optical and μCT imaging in an orthopaedic implant infection in mice PLoS One 20127(10)e47397 doi 101371journalpone0047397 Epub 2012 Oct 17

Rick Bowen MD

1 POSNA Traveling Fellowship Recipient (2008) 2 Bowen RE Scaduto AA Banuelos S Does early

thoracic fusion exacerbate preexisting restrictive lung disease in congenital scoliosis patients J Pediatr Orthop 28 506-511 2008

3 Bowen RE Scaduto AA Banuelos S Decreased body mass index and restrictive lung disease in congenital thoracic scoliosis J Pediatr Orthop 28665-8 2008

4 Bowen RE Gardner S Scaduto AA Eagan M Beckstead J Efficacy of intraoperative cell salvage systems in pediatric idiopathic scoliosis patients undergoing posterior spinal fusion with segmental spinal instrumentationSpine (Phila Pa 1976) 35246-51 2010

5 Bowen RE Knee injuries in the youth athlete Curr Orthop Prac 2012 23 422-428

Susan Bukata MD 1 Houck J Kneiss J Bukata SV Puzas JE Analysis of

vertical ground reaction force variables during a Sit to Stand task in participants recovering from a hip fracture Clin Biomech 2011 Jun 26(5) 470-6

2 Takahata M Awad HA OrsquoKeefe RJ Bukata SV Schwarz EM Endogenous tissue engineering PTH therapy for skeletal repair Cell Tissue Res 2011 May 31 [Epub ahead of print]

3 Kates SL Bukata SV DiGiovanni BF Friedman SL et al A guide to improving the care of patients with fragility fractures Geriatric Orthopaedic Surgery amp Rehabilitation 2011 2(1) 5-37

4 Sampson ER Chen D Schwarz EM Bukata SV OrsquoKeefe RJ Awad H Puzas JE Zuscik MJ Rosier RN Teriparatide as a chondro-regenerative therapy for injury-induced knee osteoarthritis Science Translational Medicine 2011 Sept 21 3(101) 101ra93

5 Kneiss JA Houck JR Bukata SV Puzas JE Influence of Upper Extremity Assistance on Lower Extremity Force Application Symmetry in Individuals Post-Hip Fracture During the Sit-to-Stand Task Journal of Orthopaedic amp Sports Physical Therapy 2012 May 42(5) 474-481

Michael Daubs MD

1 Patton CM Hung M Lawrence BD Patel A Woodbury AM Brodke DS Daubs MD Psychological Distress in a Department of Veteransrsquo Affairs Spine Patient Population The Spine J 2011 Nov 15 (epub ahead of print)

2 Daubs MD Lenke LG Kim YJ Cheh G Stobbs G Bridwell KH Does Correction of Preoperative Coronal Imbalance Make a Difference in Outcomes of Adult Deformity Patients Accepted for publication Spine June 2012

3 Daubs MD Patel AA Lawrence BD Brodke DS Excision of the Posterior Longitudinal Ligament During Anterior Cervical Corpectomy A Biomechanical Study Accepted for publication September 12 2012J Spinal Disorders

4 Daubs MD Lenke LG Cheh G Bridwell KH Kim YJ Stobbs G Decompression Alone Versus Decompression with Limited Fusion for the Treatment of Degenerative Lumbar Scoliosis in the Elderly Patient Accepted for publication Sept 5 2012Evidence Based Spine Journal

5 Tan Y Montgomery SR Aghdasi BG Inoue H Kaner T Tian H Terrell R Zhang X Wang JC Daubs MD The Effect of Corticosteroid Administration on Soft Tissue Inflammation Associated with rhBMP-2 use in a Rodent Model of Inflammation Spine (Phila Pa 1976) 2012 Nov 28 [Epub ahead of print]

13

MD MPH and Richard Bowen MD UCLA residency class of 2001) trauma (Mauricio Silva MD) tumor (Francis Cyran MD) and scoliosis (Richard Bowen MD and Anthony Scaduto MD UCLA residency class of 2002) Our multidisciplinary clinics offer unique comprehensive care for spina bifida muscle disease osteogenesis imperfecta hemophilia and limb deficiencyamputation A skeletal dysplasia clinic is due to open this year (Pictured from left to right Oppenheim Zionts Scaduto Bowen Silva)

The Division of Sports Medicine was founded in 1971 by Gerald Finerman MD (pictured) Dr Finerman has been on the UCLA faculty since then and was the former Department Chair from 1996-2009 He will join the Emeritus faculty in July 2013 and continue his involvement with medical student resident and fellow teaching The Division is now led by David McAllister MD Division Chief and Program Director of the Sports Medicine Fellowship Program Additional sports medicine faculty members include Sharon Hame MD Professor who has a special interest in hip arthroscopy and works part-time at the West Los Angeles VA Professor Robert Pedowitz MD PhD was Department Chair from 2009-2010 and specializes in shoulder and knee surgery and research in arthroscopic simulation Frank

Petrigliano MD Assistant Professor and UCLA resident class of 2009 focuses his clinical and research activity in shoulder surgery and sports medicine Dr Petrigliano studies the basic science of rotator cuff disease at UCLA is clinical faculty at both the VA and Olive View Medical Center As of March 1st 2013 Seth Gamradt MD (UCLA resident class of 2006) will join the USC faculty as Associate Professor and Director of Orthopaedic Athletic Medicine for USC Athletics Dr Gamradt is a specialist in shoulder surgery and sports medicine with interests in shoulder replacement and knee ligament reconstruction Still a friend in spite of his ldquodefectionrdquo we wish him the best of luck and appreciate this unique opportunity for him The sports medicine faculty members see patients at both the Westwood and Santa Monica campuses These physicians serve as the exclusive provider of medical services to the UCLA Athletic Department They continue to provide care for more than 700 UCLA intercollegiate athletes at the Acosta Athletic Training Complex and provide musculoskeletal care at the Arthur Ashe Student Health and Wellness Center

SPORTS MEDICINE

The Division of Non-Operative Sports Medicine continues to be active in advancing clinical care both the office as well as on the sidelines with the UCLA Bruins In addition the Division conducts important research and members of the faculty hold national leadership positions The Division has also been active in using musculoskeletal ultrasound at the point of care for office-based procedures and diagnosis Division Chief John DiFiori MD recently served as Co-Director of the very successful UCLA Musculoskeletal Ultrasound Course which featured a cadaver lab for procedural training In the research arena Dr DiFiori is participating in a multicenter study on the long-term effects of sport-related concussion that was recently funded by the NCAA Aurelia Nattiv MD Director of the Osteoporosis Center recently published a five-year study on restoration of normal menses in college athletes with menstrual

SPORTS MEDICINENON-OPERATIVE ORTHOPAEDICS

14

disturbances Heather Gillespie MD MPH Director of the Pediatric Sports Medicine Service at Orthopaedic Hospital has recently completed research examining sports-related injuries presenting to an inner city underserved population Daniel Vigil MD joins the faculty in March from Kaiser Los Angeles The UCLA primary care sports medicine fellowship program attracts outstanding applicants from across the country

Though the AO technique was brought to UCLA in 1978 by Dr Tony Headly it was Eric Johnson MD FRCSI (Hon) (UCLA residency class of 1981) who

established the orthopaedic trauma program in 1982 Dr Johnson is the Division Chief and he specializes in orthopaedic traumatology and fracture surgery He serves as a Member of the Board of Directors of the AO Foundation and was awarded an Honorary Fellowship in the Royal College of Surgeons in Ireland on July 13 2009 Dublin Ireland (pictured above) In 2011 Dr Johnson was the guest of honor at the 23rd at the Letournel Pelvic and Acetabular Fracture Course in Paris France In September 2011 he gave the Keynote Lecture 30 Years of Acetabular Fracture Surgery and traveled to Ireland in November 2011 to give four lectures at the 10th Current Controversies in Trauma Management Royal College of Surgeons Dr Johnson continues to travel lecture and teach as part of his commitment to the AO Foundation

TRAUMA SURGERY

Devon Jeffcoat MD (UCLA resident class of 2009) joined the faculty at UCLA in 2010 after completing his fellowship at the Hospital for Special Surgery in New York under the tutelage of Dr David Helfet Dr Jeffcoat volunteered his time during the earthquake crisis in Haiti He has already developed a busy trauma surgery practice and became a mainstay for orthopaedics at the Westwood campusrsquo Level I trauma center Ronald Reagan-UCLA Medical Center Eric D Farrell MD joined the UCLA orthopaedic trauma staff in August 2011 He previously spent more than six years as Assistant Director of Orthopaedic Trauma at Cooper University Hospital in Camden NJ His training consisted of a trauma fellowship at Harborview Medical Center in Seattle WA AO Fellowship in Salzburg Austria and an Ilizarov Fellowship in Lecco Italy He has a particular interest in nonunions and deformity correction

15

ORTHOPAEDIC RESEARCH

In 2011 Orthopaedic Hospital celebrated its 100-year anniversary (see appended photos below of OH in 1917 and 2011) For the last two decades the century-old research mission at the Orthopaedic Hospital has flourished under the direction of Harry McKellop PhD and his discovery of orthopaedic device components with

greatly improved durability and longevity The standard for excellence in orthopaedic research at UCLA was set by Marshall Urist MD who discovered and ushered in the clinical use of bone morphogenetic protein to build back human bone where it was needed to make new bone for skeletal stability 1998 saw the alliance of the UCLA Department of Orthopaedic Surgery and Orthopaedic Hospital with a commitment to preserve the rich patient-oriented research mission embraced by both

HISTORICAL PERSPECTIVE

2007 witnessed the first step of the alliancersquos vision to expand the mission of the two institutions to become among the best orthopaedic research centers in the world with the opening of the Cesar Pelli-designed-Orthopaedic Hospital Research Center at the heart of the Court of Sciences on the UCLA Westwood campus (pictured on next page) As Director of the Orthopaedic Hospital Research Center John Adams MD (pictured below) was charged with realizing this expanded vision by mounting a bold recruiting effort to create an interschool (ie medicine engineering dentistry

etc) transdisciplinary

extramurally-funded bench-to-bedside team science approach to childhood and

adult musculoskeletal disease The recruitment effort culminated this spring with the addition of 22 new faculty members from around the world to laboratories in the Orthopaedic Hospital Research Center

RESEARCH BASIC SCIENCE AND TRANSLATIONAL

Highlights of this expansion from 2007 include 1) a 10-fold increase to $55M in annual peer-reviewed grant funding coming to the Department moving the Department to number seven on the list of the top NIH-granted departments in the country 2) the first ever NIH training grant in Orthopaedic Surgery for UCLA principled by John Adams MD and Karen Lyons PhD (pictured above) representing the only such training grant in orthopaedic surgery west of St Louis 3) the first ever large-scale grant ($56M total) from the California Institute for Regenerative Medicine for bone regeneration research principled by Chia Soo MD and Bruno Peault PhD and 4) presentation to the Department of Orthopaedic Surgery of an $82 million Clinical and Translational Science Award by the NIH the largest single grant to the David Geffen School of Medicine at UCLA None of these efforts would have been possible without advice

16

support and teamwork contributed by the Broad Stem Cell Institute the Jonsson Comprehensive Cancer Center the Department of Molecular Cell and Developmental Biology in the UCLA College of Letters and Science and the Clinical and Translational Science Institute

The Orthopaedic Hospital Research Center on the Westwood campus provides a fertile environment for our researchers

and clinicians to innovate and collaborate in pediatric orthopaedic science Karen Lyons PhD has received international awards for her breakthrough work in skeletal development and growth-plate biology while Deborah Krakow MD and Dan Cohn PhD (both pictured above) have identified several key genetic mutations that cause dwarfism These discoveries have lead to a better understanding of bone diseases that affect children and are the basis for novel future treatments Our clinicians and scientists are also focused on translational research that enhances orthopaedic treatment for children by improving surgical techniques and non-surgical care In collaboration with the pediatric spine surgeons Sophia Sangiorgio PhD and Edward Ebramzadeh PhD have developed an experimental model to test and compare surgical techniques used in scoliosis surgery Their work will be presented at this yearrsquos Scoliosis Research Society meeting Mauricio Silva MD maintains one of the largest prospective pediatric trauma registries in the country The analysis of this database has resulted in several recent JBJS publications that are likely to shape the evidence-based treatment of pediatric elbow fractures He and Fabrizio Billi PhD are also collaborating with scientists in UCLArsquos School of Engineering to develop a wireless technology that can improve the fit and function of casts used to treat childrenrsquos fractures In the field of motor disorders Eileen Fowler PhD PT (pictured) and

her team have recently developed and validated a method to measure selective motor control that can predict the success of surgery for patients with cerebral palsy We are proud of the

UCLAOrthopaedic Hospital partnership and the significant contributions our pediatric orthopaedic clinicians and scientists have made We look forward to further advances that help children overcome their musculoskeletal injuries and disease The Orthopaedic Hospital Research Center remains dedicated to its founding principles First that major advances in understanding the pathobiology and management of those diseases that are most frequently encountered by the practicing orthopaedic surgeon (eg fractures joint instability etc) can be best achieved by teams of scientists with expertise ranging from molecular biology to clinical care of patients Second understanding the developmental events that shape formation of the musculoskeletal system from fetal to adult life will inform us about the deconstruction of the system that happens with aging and disease Third that development of mouse models of common human orthopaedic disease where genes in the mouse can be ldquoknocked outrdquo or amplified will allow us to develop ldquopersonalized-rdquo molecularly-targeted preventative and treatment regimens Finally by bringing the cadre of clinician-scientists into a

17

common practice setting in the new Orthopaedic Hospital in at the Santa Monica-UCLA Medical Center and Orthopaedic Hospital we hope to translate basic discoveries made in the Orthopaedic Hospital Research Center to a new standard of orthopaedic health care for both children and adults

Another study is focusing on bone formation as well as spinal fusion We are utilizing bone graft substitutes along with the appropriate growth factors to optimize the healing of the spinal fusions through the least amount of invasiveness with minimally invasive techniques Our previous studies have shown that with gene therapy we have been able to achieve spinal fusion in a very efficient manner We hope to optimize this with

the use of new bone graft materials with new growth factors in order to obtain 100 spinal fusion ultimately for our patients We hope to start clinical trials in this soon Another study we are looking at is the suppression of tumors One of the growth factors that we have invented in our laboratory here at UCLA has shown an effect to inhibit BMP bone morphogenic growth factors many tumors rely on to grow We have shown the addition of this novel growth factor can suppress the growth of tumor cells We have initiated a project where we are attempting to use this novel protein to inhibit the growth of tumors We ultimately hope that this will act as a new therapeutic method in the fight against cancer A new technology of dynamic MRI imaging will allow us to identify the pathology for patients with spine problems We have previously published over 18 scientific articles looking at the effect of dynamic motion MRI in identifying spinal pathology We are perfecting this technique and hope to institute this as a part of our standard treatment protocol for patients with spinal problems

RESEARCH THE UCLA SPINE PROGRAM The Spine Service continues to explore new areas in both basic science and clinical research in the area of spinal disorders We have a world-class laboratory that continues to attract surgeons on an international level to come and participate in our research efforts We have seven ongoing international fellowships for surgeons to come and collaborate on our research projects One of our publications was named the outstanding paper award this past year by The Spine Journal We recently received an OREF (Orthopaedic Research and Education Foundation) grant for starting a biologics registry for spinal fusion Our basic science efforts encompass several novel projects for regeneration of the spinal tissuesdiscs We are utilizing the most novel gene therapy transfer techniques along with pleuripotent stem cells in order to regenerate the disc Through our previous work of injecting growth factors into disc we have been able to generate these discs in our prior studies We are trying to optimize this effect with the addition of stem cell technology to optimize the number of cells the concentration of growth factors as well as the optimal gene transfer in order to perfect the best technique to regenerate the disc We hope that this will soon move from the animal models into human trials

The Division of Sports Medicine continues to be productive in a number of research areas Our orthopaedic biomechanics lab has expanded with the addition of Daniel Boguszewski PhD Dr Boguszewski obtained his PhD from the University of Cincinnati where he developed expertise with a sophisticated robotic testing apparatus We recently acquired an industrial robot (pictured on next page) for mechanical testing and are looking forward to coupling this exciting new technique with existing techniques pioneered by Keith Markolf PhD Our bioengineers along with Drs David McAllister and Frank Petrigliano have formed a new collaboration with the UCLA Electrical Engineering Department Wireless Health initiative to develop novel ways to measure knee biomechanics and knee injury mechanisms in patients Drs McAllister and Petrigliano have established a lab at the Greater Los Angeles VA Medical Center and continue to collaborate with Ben Wu DDS PhD in the Department of

RESEARCH THE UCLA SPORTS MEDICINE PROGRAM

18

Bioengineering and Patricia Zuk PhD in the Department of Plastic Surgery on tissue engineering for ACL reconstruction and rotator cuff repair Drs Sharon Hame and David McAllister continue to participate in clinical research including outcomes of ACL reconstruction Both are co-investigators in the NIH-funded multicenter ACL Revision Surgery (MARS) study Both also continue to collect and analyze data on primary ACL reconstruction Drs Hame McAllister Gamradt and Petrigliano have all recently completed studies on the incidence of shoulder and knee procedures using the Peardiver database

19

Jeffrey Eckardt MD Professor and Chair Orthopaedic Surgery UCLA

Anthony Scaduto MD Executive Vice Chair and President and CAO LAOH

Jeffrey Wang MD Vice Chair of Clinical Operations Orthopaedic Surgery UCLA

John Adams MD Vice Chair of Research Orthopaedic Surgery UCLA

James Luck MD Residency Program Director Orthopaedic Surgery UCLAOH

FACULTY There are presently 73 faculty members in our Department of Orthopaedic Surgery

Foot and Ankle Surgery Andrea Cracchiolo III MD (Emeritus) Nelson SooHoo MD (Division Chief) Lewis Zionts MD

General Orthopaedics Peter Alexakis MD Bruce Brown MD PhD S Andrew Schwartz MD

Hand Surgery Kodi Azari MD Prosper Benhaim MD (Division Chief) Scott Mitchell MD

Joint Replacement Benjamin Bengs MD Bruce Brown MD PhD Francis Cyran MD Gerald Finerman MD Eric Johnson MD James Luck MD Bert Thomas MD (Division Chief)

Musculoskeletal Oncology Susan Bukata MD Francis Cyran MD Jeffrey Eckardt MD (Division Chief)

Osteoporosis John Adams MD Susan Bukata MD Aurelia Nattiv MD

Pediatric OrthopaedicsOrthopaedic Hospital Richard Bowen MD James Luck MD William Oppenheim MD Anthony Scaduto MD (Division Chief) Mauricio Silva MD Lewis Zionts MD

Spine SurgeryPMampR Richard Bowen MD Michael Daubs MD David Fish MD MPH (PMampR) Jae Jung MD (PMampR) Anthony Scaduto MD A Nick Shamie MD Jeffrey Wang MD (Division Chief)

Sports Medicine Richard Bowen MD Gerald Finerman MD Sharon Hame MD David McAllister MD (Division Chief) Robert Pedowitz MD PhD

Frank Petrigliano MD

Sports Medicine amp Non-Operative Orthopaedics John DiFiori MD (Division Chief) Heather Gillespie MD MPH Aurelia Nattiv MD Daniel Vigil MD

Trauma Surgery Benjamin Bengs MD Eric Farrell MD Devon Jeffcoat MD Eric Johnson MD (Division Chief)

Shriners Hospital Katherine Au MD Robert Cho MD Anna Cuomo MD Kathryn Doughty MD Colin Mosely MD Kit Song MD (Service Chief) Hugh Watts MD

VA Hospital Bruce Brown MD PhD Francis Cyran MD Sharon Hame MD Eric Johnson MD David McAllister MD Scott Mitchell MD Frank Petrigliano MD Nelson SooHoo MD (Service Chief) Bert Thomas MD Steven Zeitzew MD

Research Faculty John Adams MD (Vice Chair of Research) Maria-Grazia Ascenzi PhD Paul Bajaj PhD Fabrizio Billi PhD Daniel Boguszewski PhD Patricia Campbell PhD Daniel Cohn PhD Gay Crooks PhD Edward Ebramzadeh PhD Denis Evseenko MD PhD Eileen Fowler PhD PT Martin Hewison PhD Luisa Iruela-Arispe PhD Deborah Krakow MD Susan Krum PhD Timothy Lane PhD Philip Liu PhD Daniel Lu MD PhD Zhen Lu PhD Karen Lyons PhD Keith Markolf PhD Harry McKellop PhD Shen Pang PhD Sang-Hyun Park PhD Bruno Peault PhD Sophia Sangiorgio PhD Fu Wen Shen PhD B Chia Soo MD Kang Ting DMD Howard Winet PhD Benjamin Wu DDS PhD

20

RECENT FACULTY HONORS AND PUBLICATIONS John Adams MD

1 Vitamin D 3rd Edition Feldman DR Pike JW Adams JS eds San Diego Elsevier Press 2011

2 Chen H Gilbert LC Lu X Liu Z You S Weitzmann MN Nanes MS Adams JS Estrogen response element binding protein stimulates osteoclastogenesis and bone resorption J Bone Min Res 262537-2547 2011 PMCID PMC3417837

3 Fabri M Stenger S Shin D Yuk J Liu PT Realegeno S Lee H Krutzik SR Schenk M Sieling PA Teles R Montoya D Iyer SS Bruns H Lewinsohn DM Hollis BW Hewison M Adams JS Steinmeyer A Zuumlgel U Cheng G Jo E Bloom BR Modlin RL Vitamin D is required for IFN-γ mediated antimicrobial activity of human macrophages Sci Transl Med 3104ra102 2011 PMCID PMC3269210

4 Billi F Benya B Kavanaugh A Adams JS Ebramzadeh E McKellop H The John Charnley Award An accurate and extremely sensitive method to separate display and characterize wear debris part 1ndashpolythylene particles Clin Orthopaed Rel Res 470329-338 2012 PMCID PMC 3254734

5 James AW Pang S Askarinam A Corselli M Zara JN Goyal R Chang L Pan A Shen J Yuan W Stoker D Zhang X Adams JS Ting K Soo C Additive effects of sonic hedgehog and Nell-1 signaling in osteogenic versus adipogenic differentiation of human adipose-derived stromal cells Stem Cells Dev 212170-2178 2012 PMCID PMC3411358

Kodi Azari MD 1 Azari K Imbriglia JE Goitz RJ Shores JT Balk ML

Brandacher G Schneeberger S Gorantla V Lee WPldquoHandTransplantion The Donor and Operationrdquo Journal of Reconstructive Microsurgery (2012) 28(1) 27-34

2 Sue McDiarmid and Kodi Azari ldquoDonor Related Issues in Hand Transplantaionrdquo Hand Clinics (2011) 274 545-54

3 Tristan L Hartzell Prosper Benhaim Joeseph E Imbriglia Jaimie Shores Robert J Goitz Marshall Balk Scott Mitchell Roee Rubinstein Vijay Gorantla Stephan Schneeberger Gerald Brandacher W P Andrew LeeKodi K Azari ldquoSurgical and Technical Aspects of Hand Transplantation ndash Is it Just Another Replantrdquo Hand Clinics (2011) 274 521-30

4 Immune Modulation for Hand Transplantation Changing the Risk-Benefit Balance Brandacher G Gorantla VS Schneeberger S Shores JT Imbriglia JE Azari K Donnenberg AD Cooney DS Losee JE Lee WPA J Healthcare Science Humanities 20111(4)62-68

5 Elaine Horibe Song Afshin Shirazian Brian

Binns Yuedi Fleming Lydia M Ferreira Rod J Rohrich Kodi Azari ldquoBenchmarking academic plastic surgery services in the USrdquo Plastic and Reconstructive Surgery (2012) 129(6)1407-18

Benjamin Bengs MD

1 Bengs BC Sangiorgio SN Ebramzadeh E Achieving Clinically Adequate Stem Fixation Despite Severe Proximal Femoral Bone Loss Poster P039 Orthopedic Research Society Annual Meeting San Fransisco CA 2012

2 Sangiorgio S Knutsen A Kalma J Ebramzadeh E Bengs B Can a Dual-tapered Press-fit Stem be used in Cases with Severe Proximal Femoral Defects AAOS Poster 2043 Annual Meeting in San Francisco CA

3 Sugi M Sheridan K Lewis L Huang MH Nattiv A Kado DM BC Bengs Active referral intervention following fragility fractures leads to enhanced osteoporosis follow-up carerdquo Journal of Osteoporosis (accepted 2012)

4 Sangiorgio S Ebramzadeh E Knutsen A Kalma J Bengs B Can a Dual-tapered Press-fit Stem be used in Cases with Severe Proximal Femoral Defects Journal of Biomaterials and Biomechanics (accepted 2012)

5 Aaron W James Jia Shen Xinli Zhang Michael Chiang Asal Askarinam Raghav Goyal Alan Nguyen Janette N Zara Greg Asatrian Jonguk Chung Benjamin Bengs Cymbeline T Culiat A Simon Turner Howard B Seim III John S Adams Kang Ting Chia Soo Nell-1 Regulates Osteoblast Osteoclast Activity and Activates Wntβ-catenin Signaling A New Cause and Treatment for Osteoporosis (submitted for publication)

Prosper Benhaim MD 1 Benhaim P Anthony JP Lin LYT McCalmont TH

Mathes SJ A long-term study of allogeneic rat hindlimb transplants immunosuppressed with RS-61443 Transplantation 1993 56(4) 911-917

2 Tejwani SG Markolf KL Benhaim P Graft reconstruction of the interosseous membrane in conjunction with metallic radial head replacement a cadaveric study Journal of Hand Surgery 2005 30A(2) 335-342

3 Markolf KL Tejwani SG Benhaim P Effects of wafer resection and hemiresection from the distal ulna on load-sharing at the wrist a cadaveric study Journal of Bone and Joint Surgery 2005 30A(2) 351-358

4 Dragoo JL Lieberman JR Lee RS DeUgarte DA Lee Y Zuk PA Hedrick MH Benhaim P ldquoTissue engineered bone from BMP-2 transduced stem cells derived from human fat Plastic and Reconstructive Surgery 2005 115(6) 1665-1673

21

5 Dragoo JL Carlson G McCormick F Khan-Farooqi H Zhu M Zuk PA Benhaim P Healing full-thickness cartilage defects using adipose-derived stem cells Tissue Engineering 2007 13(7) 1615-1621

Nicholas Bernthal MD

1 Kremen TJ Jr Bernthal NM Eckardt MA Eckardt JJ Giant cell tumor of bone are we stratifying results appropriately Clin Orthop Relat Res 2012 Mar470(3)677-83

2 Bernthal NM Federman N Eilber FR Nelson SD Eckardt JJ Eilber FC Tap WD Long-term results (gt25 years) of a randomized prospective clinical trial evaluating chemotherapy in patients with high-grade operable osteosarcoma Cancer 2012 Dec 1118(23)5888-93 doi 101002cncr27651 Epub 2012 May 30

3 Pribaz JR Bernthal NM Wong TC Silva M Lateral spurring (overgrowth) after pediatric lateral condyle fractures J Pediatr Orthop 2012 Jul-Aug32(5)456-60

4 Silva M Knutsen AR Kalma JJ Borkowski SL Bernthal NM Spencer HT Sangiorgio SN Ebramzadeh E Biomechanical Testing of Pin Configurations in Supracondylar Humeral Fractures The Effect of Medial Column Comminution J Orthop Trauma 2012 Aug 28 [Epub ahead of print]

5 Niska JA Meganck JA Pribaz JR Shahbazian JH Lim E Zhang N Rice BW Akin A Ramos RI Bernthal NM Francis KP Miller LS Monitoring bacterial burden inflammation and bone damage longitudinally using optical and μCT imaging in an orthopaedic implant infection in mice PLoS One 20127(10)e47397 doi 101371journalpone0047397 Epub 2012 Oct 17

Rick Bowen MD

1 POSNA Traveling Fellowship Recipient (2008) 2 Bowen RE Scaduto AA Banuelos S Does early

thoracic fusion exacerbate preexisting restrictive lung disease in congenital scoliosis patients J Pediatr Orthop 28 506-511 2008

3 Bowen RE Scaduto AA Banuelos S Decreased body mass index and restrictive lung disease in congenital thoracic scoliosis J Pediatr Orthop 28665-8 2008

4 Bowen RE Gardner S Scaduto AA Eagan M Beckstead J Efficacy of intraoperative cell salvage systems in pediatric idiopathic scoliosis patients undergoing posterior spinal fusion with segmental spinal instrumentationSpine (Phila Pa 1976) 35246-51 2010

5 Bowen RE Knee injuries in the youth athlete Curr Orthop Prac 2012 23 422-428

Susan Bukata MD 1 Houck J Kneiss J Bukata SV Puzas JE Analysis of

vertical ground reaction force variables during a Sit to Stand task in participants recovering from a hip fracture Clin Biomech 2011 Jun 26(5) 470-6

2 Takahata M Awad HA OrsquoKeefe RJ Bukata SV Schwarz EM Endogenous tissue engineering PTH therapy for skeletal repair Cell Tissue Res 2011 May 31 [Epub ahead of print]

3 Kates SL Bukata SV DiGiovanni BF Friedman SL et al A guide to improving the care of patients with fragility fractures Geriatric Orthopaedic Surgery amp Rehabilitation 2011 2(1) 5-37

4 Sampson ER Chen D Schwarz EM Bukata SV OrsquoKeefe RJ Awad H Puzas JE Zuscik MJ Rosier RN Teriparatide as a chondro-regenerative therapy for injury-induced knee osteoarthritis Science Translational Medicine 2011 Sept 21 3(101) 101ra93

5 Kneiss JA Houck JR Bukata SV Puzas JE Influence of Upper Extremity Assistance on Lower Extremity Force Application Symmetry in Individuals Post-Hip Fracture During the Sit-to-Stand Task Journal of Orthopaedic amp Sports Physical Therapy 2012 May 42(5) 474-481

Michael Daubs MD

1 Patton CM Hung M Lawrence BD Patel A Woodbury AM Brodke DS Daubs MD Psychological Distress in a Department of Veteransrsquo Affairs Spine Patient Population The Spine J 2011 Nov 15 (epub ahead of print)

2 Daubs MD Lenke LG Kim YJ Cheh G Stobbs G Bridwell KH Does Correction of Preoperative Coronal Imbalance Make a Difference in Outcomes of Adult Deformity Patients Accepted for publication Spine June 2012

3 Daubs MD Patel AA Lawrence BD Brodke DS Excision of the Posterior Longitudinal Ligament During Anterior Cervical Corpectomy A Biomechanical Study Accepted for publication September 12 2012J Spinal Disorders

4 Daubs MD Lenke LG Cheh G Bridwell KH Kim YJ Stobbs G Decompression Alone Versus Decompression with Limited Fusion for the Treatment of Degenerative Lumbar Scoliosis in the Elderly Patient Accepted for publication Sept 5 2012Evidence Based Spine Journal

5 Tan Y Montgomery SR Aghdasi BG Inoue H Kaner T Tian H Terrell R Zhang X Wang JC Daubs MD The Effect of Corticosteroid Administration on Soft Tissue Inflammation Associated with rhBMP-2 use in a Rodent Model of Inflammation Spine (Phila Pa 1976) 2012 Nov 28 [Epub ahead of print]

14

disturbances Heather Gillespie MD MPH Director of the Pediatric Sports Medicine Service at Orthopaedic Hospital has recently completed research examining sports-related injuries presenting to an inner city underserved population Daniel Vigil MD joins the faculty in March from Kaiser Los Angeles The UCLA primary care sports medicine fellowship program attracts outstanding applicants from across the country

Though the AO technique was brought to UCLA in 1978 by Dr Tony Headly it was Eric Johnson MD FRCSI (Hon) (UCLA residency class of 1981) who

established the orthopaedic trauma program in 1982 Dr Johnson is the Division Chief and he specializes in orthopaedic traumatology and fracture surgery He serves as a Member of the Board of Directors of the AO Foundation and was awarded an Honorary Fellowship in the Royal College of Surgeons in Ireland on July 13 2009 Dublin Ireland (pictured above) In 2011 Dr Johnson was the guest of honor at the 23rd at the Letournel Pelvic and Acetabular Fracture Course in Paris France In September 2011 he gave the Keynote Lecture 30 Years of Acetabular Fracture Surgery and traveled to Ireland in November 2011 to give four lectures at the 10th Current Controversies in Trauma Management Royal College of Surgeons Dr Johnson continues to travel lecture and teach as part of his commitment to the AO Foundation

TRAUMA SURGERY

Devon Jeffcoat MD (UCLA resident class of 2009) joined the faculty at UCLA in 2010 after completing his fellowship at the Hospital for Special Surgery in New York under the tutelage of Dr David Helfet Dr Jeffcoat volunteered his time during the earthquake crisis in Haiti He has already developed a busy trauma surgery practice and became a mainstay for orthopaedics at the Westwood campusrsquo Level I trauma center Ronald Reagan-UCLA Medical Center Eric D Farrell MD joined the UCLA orthopaedic trauma staff in August 2011 He previously spent more than six years as Assistant Director of Orthopaedic Trauma at Cooper University Hospital in Camden NJ His training consisted of a trauma fellowship at Harborview Medical Center in Seattle WA AO Fellowship in Salzburg Austria and an Ilizarov Fellowship in Lecco Italy He has a particular interest in nonunions and deformity correction

15

ORTHOPAEDIC RESEARCH

In 2011 Orthopaedic Hospital celebrated its 100-year anniversary (see appended photos below of OH in 1917 and 2011) For the last two decades the century-old research mission at the Orthopaedic Hospital has flourished under the direction of Harry McKellop PhD and his discovery of orthopaedic device components with

greatly improved durability and longevity The standard for excellence in orthopaedic research at UCLA was set by Marshall Urist MD who discovered and ushered in the clinical use of bone morphogenetic protein to build back human bone where it was needed to make new bone for skeletal stability 1998 saw the alliance of the UCLA Department of Orthopaedic Surgery and Orthopaedic Hospital with a commitment to preserve the rich patient-oriented research mission embraced by both

HISTORICAL PERSPECTIVE

2007 witnessed the first step of the alliancersquos vision to expand the mission of the two institutions to become among the best orthopaedic research centers in the world with the opening of the Cesar Pelli-designed-Orthopaedic Hospital Research Center at the heart of the Court of Sciences on the UCLA Westwood campus (pictured on next page) As Director of the Orthopaedic Hospital Research Center John Adams MD (pictured below) was charged with realizing this expanded vision by mounting a bold recruiting effort to create an interschool (ie medicine engineering dentistry

etc) transdisciplinary

extramurally-funded bench-to-bedside team science approach to childhood and

adult musculoskeletal disease The recruitment effort culminated this spring with the addition of 22 new faculty members from around the world to laboratories in the Orthopaedic Hospital Research Center

RESEARCH BASIC SCIENCE AND TRANSLATIONAL

Highlights of this expansion from 2007 include 1) a 10-fold increase to $55M in annual peer-reviewed grant funding coming to the Department moving the Department to number seven on the list of the top NIH-granted departments in the country 2) the first ever NIH training grant in Orthopaedic Surgery for UCLA principled by John Adams MD and Karen Lyons PhD (pictured above) representing the only such training grant in orthopaedic surgery west of St Louis 3) the first ever large-scale grant ($56M total) from the California Institute for Regenerative Medicine for bone regeneration research principled by Chia Soo MD and Bruno Peault PhD and 4) presentation to the Department of Orthopaedic Surgery of an $82 million Clinical and Translational Science Award by the NIH the largest single grant to the David Geffen School of Medicine at UCLA None of these efforts would have been possible without advice

16

support and teamwork contributed by the Broad Stem Cell Institute the Jonsson Comprehensive Cancer Center the Department of Molecular Cell and Developmental Biology in the UCLA College of Letters and Science and the Clinical and Translational Science Institute

The Orthopaedic Hospital Research Center on the Westwood campus provides a fertile environment for our researchers

and clinicians to innovate and collaborate in pediatric orthopaedic science Karen Lyons PhD has received international awards for her breakthrough work in skeletal development and growth-plate biology while Deborah Krakow MD and Dan Cohn PhD (both pictured above) have identified several key genetic mutations that cause dwarfism These discoveries have lead to a better understanding of bone diseases that affect children and are the basis for novel future treatments Our clinicians and scientists are also focused on translational research that enhances orthopaedic treatment for children by improving surgical techniques and non-surgical care In collaboration with the pediatric spine surgeons Sophia Sangiorgio PhD and Edward Ebramzadeh PhD have developed an experimental model to test and compare surgical techniques used in scoliosis surgery Their work will be presented at this yearrsquos Scoliosis Research Society meeting Mauricio Silva MD maintains one of the largest prospective pediatric trauma registries in the country The analysis of this database has resulted in several recent JBJS publications that are likely to shape the evidence-based treatment of pediatric elbow fractures He and Fabrizio Billi PhD are also collaborating with scientists in UCLArsquos School of Engineering to develop a wireless technology that can improve the fit and function of casts used to treat childrenrsquos fractures In the field of motor disorders Eileen Fowler PhD PT (pictured) and

her team have recently developed and validated a method to measure selective motor control that can predict the success of surgery for patients with cerebral palsy We are proud of the

UCLAOrthopaedic Hospital partnership and the significant contributions our pediatric orthopaedic clinicians and scientists have made We look forward to further advances that help children overcome their musculoskeletal injuries and disease The Orthopaedic Hospital Research Center remains dedicated to its founding principles First that major advances in understanding the pathobiology and management of those diseases that are most frequently encountered by the practicing orthopaedic surgeon (eg fractures joint instability etc) can be best achieved by teams of scientists with expertise ranging from molecular biology to clinical care of patients Second understanding the developmental events that shape formation of the musculoskeletal system from fetal to adult life will inform us about the deconstruction of the system that happens with aging and disease Third that development of mouse models of common human orthopaedic disease where genes in the mouse can be ldquoknocked outrdquo or amplified will allow us to develop ldquopersonalized-rdquo molecularly-targeted preventative and treatment regimens Finally by bringing the cadre of clinician-scientists into a

17

common practice setting in the new Orthopaedic Hospital in at the Santa Monica-UCLA Medical Center and Orthopaedic Hospital we hope to translate basic discoveries made in the Orthopaedic Hospital Research Center to a new standard of orthopaedic health care for both children and adults

Another study is focusing on bone formation as well as spinal fusion We are utilizing bone graft substitutes along with the appropriate growth factors to optimize the healing of the spinal fusions through the least amount of invasiveness with minimally invasive techniques Our previous studies have shown that with gene therapy we have been able to achieve spinal fusion in a very efficient manner We hope to optimize this with

the use of new bone graft materials with new growth factors in order to obtain 100 spinal fusion ultimately for our patients We hope to start clinical trials in this soon Another study we are looking at is the suppression of tumors One of the growth factors that we have invented in our laboratory here at UCLA has shown an effect to inhibit BMP bone morphogenic growth factors many tumors rely on to grow We have shown the addition of this novel growth factor can suppress the growth of tumor cells We have initiated a project where we are attempting to use this novel protein to inhibit the growth of tumors We ultimately hope that this will act as a new therapeutic method in the fight against cancer A new technology of dynamic MRI imaging will allow us to identify the pathology for patients with spine problems We have previously published over 18 scientific articles looking at the effect of dynamic motion MRI in identifying spinal pathology We are perfecting this technique and hope to institute this as a part of our standard treatment protocol for patients with spinal problems

RESEARCH THE UCLA SPINE PROGRAM The Spine Service continues to explore new areas in both basic science and clinical research in the area of spinal disorders We have a world-class laboratory that continues to attract surgeons on an international level to come and participate in our research efforts We have seven ongoing international fellowships for surgeons to come and collaborate on our research projects One of our publications was named the outstanding paper award this past year by The Spine Journal We recently received an OREF (Orthopaedic Research and Education Foundation) grant for starting a biologics registry for spinal fusion Our basic science efforts encompass several novel projects for regeneration of the spinal tissuesdiscs We are utilizing the most novel gene therapy transfer techniques along with pleuripotent stem cells in order to regenerate the disc Through our previous work of injecting growth factors into disc we have been able to generate these discs in our prior studies We are trying to optimize this effect with the addition of stem cell technology to optimize the number of cells the concentration of growth factors as well as the optimal gene transfer in order to perfect the best technique to regenerate the disc We hope that this will soon move from the animal models into human trials

The Division of Sports Medicine continues to be productive in a number of research areas Our orthopaedic biomechanics lab has expanded with the addition of Daniel Boguszewski PhD Dr Boguszewski obtained his PhD from the University of Cincinnati where he developed expertise with a sophisticated robotic testing apparatus We recently acquired an industrial robot (pictured on next page) for mechanical testing and are looking forward to coupling this exciting new technique with existing techniques pioneered by Keith Markolf PhD Our bioengineers along with Drs David McAllister and Frank Petrigliano have formed a new collaboration with the UCLA Electrical Engineering Department Wireless Health initiative to develop novel ways to measure knee biomechanics and knee injury mechanisms in patients Drs McAllister and Petrigliano have established a lab at the Greater Los Angeles VA Medical Center and continue to collaborate with Ben Wu DDS PhD in the Department of

RESEARCH THE UCLA SPORTS MEDICINE PROGRAM

18

Bioengineering and Patricia Zuk PhD in the Department of Plastic Surgery on tissue engineering for ACL reconstruction and rotator cuff repair Drs Sharon Hame and David McAllister continue to participate in clinical research including outcomes of ACL reconstruction Both are co-investigators in the NIH-funded multicenter ACL Revision Surgery (MARS) study Both also continue to collect and analyze data on primary ACL reconstruction Drs Hame McAllister Gamradt and Petrigliano have all recently completed studies on the incidence of shoulder and knee procedures using the Peardiver database

19

Jeffrey Eckardt MD Professor and Chair Orthopaedic Surgery UCLA

Anthony Scaduto MD Executive Vice Chair and President and CAO LAOH

Jeffrey Wang MD Vice Chair of Clinical Operations Orthopaedic Surgery UCLA

John Adams MD Vice Chair of Research Orthopaedic Surgery UCLA

James Luck MD Residency Program Director Orthopaedic Surgery UCLAOH

FACULTY There are presently 73 faculty members in our Department of Orthopaedic Surgery

Foot and Ankle Surgery Andrea Cracchiolo III MD (Emeritus) Nelson SooHoo MD (Division Chief) Lewis Zionts MD

General Orthopaedics Peter Alexakis MD Bruce Brown MD PhD S Andrew Schwartz MD

Hand Surgery Kodi Azari MD Prosper Benhaim MD (Division Chief) Scott Mitchell MD

Joint Replacement Benjamin Bengs MD Bruce Brown MD PhD Francis Cyran MD Gerald Finerman MD Eric Johnson MD James Luck MD Bert Thomas MD (Division Chief)

Musculoskeletal Oncology Susan Bukata MD Francis Cyran MD Jeffrey Eckardt MD (Division Chief)

Osteoporosis John Adams MD Susan Bukata MD Aurelia Nattiv MD

Pediatric OrthopaedicsOrthopaedic Hospital Richard Bowen MD James Luck MD William Oppenheim MD Anthony Scaduto MD (Division Chief) Mauricio Silva MD Lewis Zionts MD

Spine SurgeryPMampR Richard Bowen MD Michael Daubs MD David Fish MD MPH (PMampR) Jae Jung MD (PMampR) Anthony Scaduto MD A Nick Shamie MD Jeffrey Wang MD (Division Chief)

Sports Medicine Richard Bowen MD Gerald Finerman MD Sharon Hame MD David McAllister MD (Division Chief) Robert Pedowitz MD PhD

Frank Petrigliano MD

Sports Medicine amp Non-Operative Orthopaedics John DiFiori MD (Division Chief) Heather Gillespie MD MPH Aurelia Nattiv MD Daniel Vigil MD

Trauma Surgery Benjamin Bengs MD Eric Farrell MD Devon Jeffcoat MD Eric Johnson MD (Division Chief)

Shriners Hospital Katherine Au MD Robert Cho MD Anna Cuomo MD Kathryn Doughty MD Colin Mosely MD Kit Song MD (Service Chief) Hugh Watts MD

VA Hospital Bruce Brown MD PhD Francis Cyran MD Sharon Hame MD Eric Johnson MD David McAllister MD Scott Mitchell MD Frank Petrigliano MD Nelson SooHoo MD (Service Chief) Bert Thomas MD Steven Zeitzew MD

Research Faculty John Adams MD (Vice Chair of Research) Maria-Grazia Ascenzi PhD Paul Bajaj PhD Fabrizio Billi PhD Daniel Boguszewski PhD Patricia Campbell PhD Daniel Cohn PhD Gay Crooks PhD Edward Ebramzadeh PhD Denis Evseenko MD PhD Eileen Fowler PhD PT Martin Hewison PhD Luisa Iruela-Arispe PhD Deborah Krakow MD Susan Krum PhD Timothy Lane PhD Philip Liu PhD Daniel Lu MD PhD Zhen Lu PhD Karen Lyons PhD Keith Markolf PhD Harry McKellop PhD Shen Pang PhD Sang-Hyun Park PhD Bruno Peault PhD Sophia Sangiorgio PhD Fu Wen Shen PhD B Chia Soo MD Kang Ting DMD Howard Winet PhD Benjamin Wu DDS PhD

20

RECENT FACULTY HONORS AND PUBLICATIONS John Adams MD

1 Vitamin D 3rd Edition Feldman DR Pike JW Adams JS eds San Diego Elsevier Press 2011

2 Chen H Gilbert LC Lu X Liu Z You S Weitzmann MN Nanes MS Adams JS Estrogen response element binding protein stimulates osteoclastogenesis and bone resorption J Bone Min Res 262537-2547 2011 PMCID PMC3417837

3 Fabri M Stenger S Shin D Yuk J Liu PT Realegeno S Lee H Krutzik SR Schenk M Sieling PA Teles R Montoya D Iyer SS Bruns H Lewinsohn DM Hollis BW Hewison M Adams JS Steinmeyer A Zuumlgel U Cheng G Jo E Bloom BR Modlin RL Vitamin D is required for IFN-γ mediated antimicrobial activity of human macrophages Sci Transl Med 3104ra102 2011 PMCID PMC3269210

4 Billi F Benya B Kavanaugh A Adams JS Ebramzadeh E McKellop H The John Charnley Award An accurate and extremely sensitive method to separate display and characterize wear debris part 1ndashpolythylene particles Clin Orthopaed Rel Res 470329-338 2012 PMCID PMC 3254734

5 James AW Pang S Askarinam A Corselli M Zara JN Goyal R Chang L Pan A Shen J Yuan W Stoker D Zhang X Adams JS Ting K Soo C Additive effects of sonic hedgehog and Nell-1 signaling in osteogenic versus adipogenic differentiation of human adipose-derived stromal cells Stem Cells Dev 212170-2178 2012 PMCID PMC3411358

Kodi Azari MD 1 Azari K Imbriglia JE Goitz RJ Shores JT Balk ML

Brandacher G Schneeberger S Gorantla V Lee WPldquoHandTransplantion The Donor and Operationrdquo Journal of Reconstructive Microsurgery (2012) 28(1) 27-34

2 Sue McDiarmid and Kodi Azari ldquoDonor Related Issues in Hand Transplantaionrdquo Hand Clinics (2011) 274 545-54

3 Tristan L Hartzell Prosper Benhaim Joeseph E Imbriglia Jaimie Shores Robert J Goitz Marshall Balk Scott Mitchell Roee Rubinstein Vijay Gorantla Stephan Schneeberger Gerald Brandacher W P Andrew LeeKodi K Azari ldquoSurgical and Technical Aspects of Hand Transplantation ndash Is it Just Another Replantrdquo Hand Clinics (2011) 274 521-30

4 Immune Modulation for Hand Transplantation Changing the Risk-Benefit Balance Brandacher G Gorantla VS Schneeberger S Shores JT Imbriglia JE Azari K Donnenberg AD Cooney DS Losee JE Lee WPA J Healthcare Science Humanities 20111(4)62-68

5 Elaine Horibe Song Afshin Shirazian Brian

Binns Yuedi Fleming Lydia M Ferreira Rod J Rohrich Kodi Azari ldquoBenchmarking academic plastic surgery services in the USrdquo Plastic and Reconstructive Surgery (2012) 129(6)1407-18

Benjamin Bengs MD

1 Bengs BC Sangiorgio SN Ebramzadeh E Achieving Clinically Adequate Stem Fixation Despite Severe Proximal Femoral Bone Loss Poster P039 Orthopedic Research Society Annual Meeting San Fransisco CA 2012

2 Sangiorgio S Knutsen A Kalma J Ebramzadeh E Bengs B Can a Dual-tapered Press-fit Stem be used in Cases with Severe Proximal Femoral Defects AAOS Poster 2043 Annual Meeting in San Francisco CA

3 Sugi M Sheridan K Lewis L Huang MH Nattiv A Kado DM BC Bengs Active referral intervention following fragility fractures leads to enhanced osteoporosis follow-up carerdquo Journal of Osteoporosis (accepted 2012)

4 Sangiorgio S Ebramzadeh E Knutsen A Kalma J Bengs B Can a Dual-tapered Press-fit Stem be used in Cases with Severe Proximal Femoral Defects Journal of Biomaterials and Biomechanics (accepted 2012)

5 Aaron W James Jia Shen Xinli Zhang Michael Chiang Asal Askarinam Raghav Goyal Alan Nguyen Janette N Zara Greg Asatrian Jonguk Chung Benjamin Bengs Cymbeline T Culiat A Simon Turner Howard B Seim III John S Adams Kang Ting Chia Soo Nell-1 Regulates Osteoblast Osteoclast Activity and Activates Wntβ-catenin Signaling A New Cause and Treatment for Osteoporosis (submitted for publication)

Prosper Benhaim MD 1 Benhaim P Anthony JP Lin LYT McCalmont TH

Mathes SJ A long-term study of allogeneic rat hindlimb transplants immunosuppressed with RS-61443 Transplantation 1993 56(4) 911-917

2 Tejwani SG Markolf KL Benhaim P Graft reconstruction of the interosseous membrane in conjunction with metallic radial head replacement a cadaveric study Journal of Hand Surgery 2005 30A(2) 335-342

3 Markolf KL Tejwani SG Benhaim P Effects of wafer resection and hemiresection from the distal ulna on load-sharing at the wrist a cadaveric study Journal of Bone and Joint Surgery 2005 30A(2) 351-358

4 Dragoo JL Lieberman JR Lee RS DeUgarte DA Lee Y Zuk PA Hedrick MH Benhaim P ldquoTissue engineered bone from BMP-2 transduced stem cells derived from human fat Plastic and Reconstructive Surgery 2005 115(6) 1665-1673

21

5 Dragoo JL Carlson G McCormick F Khan-Farooqi H Zhu M Zuk PA Benhaim P Healing full-thickness cartilage defects using adipose-derived stem cells Tissue Engineering 2007 13(7) 1615-1621

Nicholas Bernthal MD

1 Kremen TJ Jr Bernthal NM Eckardt MA Eckardt JJ Giant cell tumor of bone are we stratifying results appropriately Clin Orthop Relat Res 2012 Mar470(3)677-83

2 Bernthal NM Federman N Eilber FR Nelson SD Eckardt JJ Eilber FC Tap WD Long-term results (gt25 years) of a randomized prospective clinical trial evaluating chemotherapy in patients with high-grade operable osteosarcoma Cancer 2012 Dec 1118(23)5888-93 doi 101002cncr27651 Epub 2012 May 30

3 Pribaz JR Bernthal NM Wong TC Silva M Lateral spurring (overgrowth) after pediatric lateral condyle fractures J Pediatr Orthop 2012 Jul-Aug32(5)456-60

4 Silva M Knutsen AR Kalma JJ Borkowski SL Bernthal NM Spencer HT Sangiorgio SN Ebramzadeh E Biomechanical Testing of Pin Configurations in Supracondylar Humeral Fractures The Effect of Medial Column Comminution J Orthop Trauma 2012 Aug 28 [Epub ahead of print]

5 Niska JA Meganck JA Pribaz JR Shahbazian JH Lim E Zhang N Rice BW Akin A Ramos RI Bernthal NM Francis KP Miller LS Monitoring bacterial burden inflammation and bone damage longitudinally using optical and μCT imaging in an orthopaedic implant infection in mice PLoS One 20127(10)e47397 doi 101371journalpone0047397 Epub 2012 Oct 17

Rick Bowen MD

1 POSNA Traveling Fellowship Recipient (2008) 2 Bowen RE Scaduto AA Banuelos S Does early

thoracic fusion exacerbate preexisting restrictive lung disease in congenital scoliosis patients J Pediatr Orthop 28 506-511 2008

3 Bowen RE Scaduto AA Banuelos S Decreased body mass index and restrictive lung disease in congenital thoracic scoliosis J Pediatr Orthop 28665-8 2008

4 Bowen RE Gardner S Scaduto AA Eagan M Beckstead J Efficacy of intraoperative cell salvage systems in pediatric idiopathic scoliosis patients undergoing posterior spinal fusion with segmental spinal instrumentationSpine (Phila Pa 1976) 35246-51 2010

5 Bowen RE Knee injuries in the youth athlete Curr Orthop Prac 2012 23 422-428

Susan Bukata MD 1 Houck J Kneiss J Bukata SV Puzas JE Analysis of

vertical ground reaction force variables during a Sit to Stand task in participants recovering from a hip fracture Clin Biomech 2011 Jun 26(5) 470-6

2 Takahata M Awad HA OrsquoKeefe RJ Bukata SV Schwarz EM Endogenous tissue engineering PTH therapy for skeletal repair Cell Tissue Res 2011 May 31 [Epub ahead of print]

3 Kates SL Bukata SV DiGiovanni BF Friedman SL et al A guide to improving the care of patients with fragility fractures Geriatric Orthopaedic Surgery amp Rehabilitation 2011 2(1) 5-37

4 Sampson ER Chen D Schwarz EM Bukata SV OrsquoKeefe RJ Awad H Puzas JE Zuscik MJ Rosier RN Teriparatide as a chondro-regenerative therapy for injury-induced knee osteoarthritis Science Translational Medicine 2011 Sept 21 3(101) 101ra93

5 Kneiss JA Houck JR Bukata SV Puzas JE Influence of Upper Extremity Assistance on Lower Extremity Force Application Symmetry in Individuals Post-Hip Fracture During the Sit-to-Stand Task Journal of Orthopaedic amp Sports Physical Therapy 2012 May 42(5) 474-481

Michael Daubs MD

1 Patton CM Hung M Lawrence BD Patel A Woodbury AM Brodke DS Daubs MD Psychological Distress in a Department of Veteransrsquo Affairs Spine Patient Population The Spine J 2011 Nov 15 (epub ahead of print)

2 Daubs MD Lenke LG Kim YJ Cheh G Stobbs G Bridwell KH Does Correction of Preoperative Coronal Imbalance Make a Difference in Outcomes of Adult Deformity Patients Accepted for publication Spine June 2012

3 Daubs MD Patel AA Lawrence BD Brodke DS Excision of the Posterior Longitudinal Ligament During Anterior Cervical Corpectomy A Biomechanical Study Accepted for publication September 12 2012J Spinal Disorders

4 Daubs MD Lenke LG Cheh G Bridwell KH Kim YJ Stobbs G Decompression Alone Versus Decompression with Limited Fusion for the Treatment of Degenerative Lumbar Scoliosis in the Elderly Patient Accepted for publication Sept 5 2012Evidence Based Spine Journal

5 Tan Y Montgomery SR Aghdasi BG Inoue H Kaner T Tian H Terrell R Zhang X Wang JC Daubs MD The Effect of Corticosteroid Administration on Soft Tissue Inflammation Associated with rhBMP-2 use in a Rodent Model of Inflammation Spine (Phila Pa 1976) 2012 Nov 28 [Epub ahead of print]

15

ORTHOPAEDIC RESEARCH

In 2011 Orthopaedic Hospital celebrated its 100-year anniversary (see appended photos below of OH in 1917 and 2011) For the last two decades the century-old research mission at the Orthopaedic Hospital has flourished under the direction of Harry McKellop PhD and his discovery of orthopaedic device components with

greatly improved durability and longevity The standard for excellence in orthopaedic research at UCLA was set by Marshall Urist MD who discovered and ushered in the clinical use of bone morphogenetic protein to build back human bone where it was needed to make new bone for skeletal stability 1998 saw the alliance of the UCLA Department of Orthopaedic Surgery and Orthopaedic Hospital with a commitment to preserve the rich patient-oriented research mission embraced by both

HISTORICAL PERSPECTIVE

2007 witnessed the first step of the alliancersquos vision to expand the mission of the two institutions to become among the best orthopaedic research centers in the world with the opening of the Cesar Pelli-designed-Orthopaedic Hospital Research Center at the heart of the Court of Sciences on the UCLA Westwood campus (pictured on next page) As Director of the Orthopaedic Hospital Research Center John Adams MD (pictured below) was charged with realizing this expanded vision by mounting a bold recruiting effort to create an interschool (ie medicine engineering dentistry

etc) transdisciplinary

extramurally-funded bench-to-bedside team science approach to childhood and

adult musculoskeletal disease The recruitment effort culminated this spring with the addition of 22 new faculty members from around the world to laboratories in the Orthopaedic Hospital Research Center

RESEARCH BASIC SCIENCE AND TRANSLATIONAL

Highlights of this expansion from 2007 include 1) a 10-fold increase to $55M in annual peer-reviewed grant funding coming to the Department moving the Department to number seven on the list of the top NIH-granted departments in the country 2) the first ever NIH training grant in Orthopaedic Surgery for UCLA principled by John Adams MD and Karen Lyons PhD (pictured above) representing the only such training grant in orthopaedic surgery west of St Louis 3) the first ever large-scale grant ($56M total) from the California Institute for Regenerative Medicine for bone regeneration research principled by Chia Soo MD and Bruno Peault PhD and 4) presentation to the Department of Orthopaedic Surgery of an $82 million Clinical and Translational Science Award by the NIH the largest single grant to the David Geffen School of Medicine at UCLA None of these efforts would have been possible without advice

16

support and teamwork contributed by the Broad Stem Cell Institute the Jonsson Comprehensive Cancer Center the Department of Molecular Cell and Developmental Biology in the UCLA College of Letters and Science and the Clinical and Translational Science Institute

The Orthopaedic Hospital Research Center on the Westwood campus provides a fertile environment for our researchers

and clinicians to innovate and collaborate in pediatric orthopaedic science Karen Lyons PhD has received international awards for her breakthrough work in skeletal development and growth-plate biology while Deborah Krakow MD and Dan Cohn PhD (both pictured above) have identified several key genetic mutations that cause dwarfism These discoveries have lead to a better understanding of bone diseases that affect children and are the basis for novel future treatments Our clinicians and scientists are also focused on translational research that enhances orthopaedic treatment for children by improving surgical techniques and non-surgical care In collaboration with the pediatric spine surgeons Sophia Sangiorgio PhD and Edward Ebramzadeh PhD have developed an experimental model to test and compare surgical techniques used in scoliosis surgery Their work will be presented at this yearrsquos Scoliosis Research Society meeting Mauricio Silva MD maintains one of the largest prospective pediatric trauma registries in the country The analysis of this database has resulted in several recent JBJS publications that are likely to shape the evidence-based treatment of pediatric elbow fractures He and Fabrizio Billi PhD are also collaborating with scientists in UCLArsquos School of Engineering to develop a wireless technology that can improve the fit and function of casts used to treat childrenrsquos fractures In the field of motor disorders Eileen Fowler PhD PT (pictured) and

her team have recently developed and validated a method to measure selective motor control that can predict the success of surgery for patients with cerebral palsy We are proud of the

UCLAOrthopaedic Hospital partnership and the significant contributions our pediatric orthopaedic clinicians and scientists have made We look forward to further advances that help children overcome their musculoskeletal injuries and disease The Orthopaedic Hospital Research Center remains dedicated to its founding principles First that major advances in understanding the pathobiology and management of those diseases that are most frequently encountered by the practicing orthopaedic surgeon (eg fractures joint instability etc) can be best achieved by teams of scientists with expertise ranging from molecular biology to clinical care of patients Second understanding the developmental events that shape formation of the musculoskeletal system from fetal to adult life will inform us about the deconstruction of the system that happens with aging and disease Third that development of mouse models of common human orthopaedic disease where genes in the mouse can be ldquoknocked outrdquo or amplified will allow us to develop ldquopersonalized-rdquo molecularly-targeted preventative and treatment regimens Finally by bringing the cadre of clinician-scientists into a

17

common practice setting in the new Orthopaedic Hospital in at the Santa Monica-UCLA Medical Center and Orthopaedic Hospital we hope to translate basic discoveries made in the Orthopaedic Hospital Research Center to a new standard of orthopaedic health care for both children and adults

Another study is focusing on bone formation as well as spinal fusion We are utilizing bone graft substitutes along with the appropriate growth factors to optimize the healing of the spinal fusions through the least amount of invasiveness with minimally invasive techniques Our previous studies have shown that with gene therapy we have been able to achieve spinal fusion in a very efficient manner We hope to optimize this with

the use of new bone graft materials with new growth factors in order to obtain 100 spinal fusion ultimately for our patients We hope to start clinical trials in this soon Another study we are looking at is the suppression of tumors One of the growth factors that we have invented in our laboratory here at UCLA has shown an effect to inhibit BMP bone morphogenic growth factors many tumors rely on to grow We have shown the addition of this novel growth factor can suppress the growth of tumor cells We have initiated a project where we are attempting to use this novel protein to inhibit the growth of tumors We ultimately hope that this will act as a new therapeutic method in the fight against cancer A new technology of dynamic MRI imaging will allow us to identify the pathology for patients with spine problems We have previously published over 18 scientific articles looking at the effect of dynamic motion MRI in identifying spinal pathology We are perfecting this technique and hope to institute this as a part of our standard treatment protocol for patients with spinal problems

RESEARCH THE UCLA SPINE PROGRAM The Spine Service continues to explore new areas in both basic science and clinical research in the area of spinal disorders We have a world-class laboratory that continues to attract surgeons on an international level to come and participate in our research efforts We have seven ongoing international fellowships for surgeons to come and collaborate on our research projects One of our publications was named the outstanding paper award this past year by The Spine Journal We recently received an OREF (Orthopaedic Research and Education Foundation) grant for starting a biologics registry for spinal fusion Our basic science efforts encompass several novel projects for regeneration of the spinal tissuesdiscs We are utilizing the most novel gene therapy transfer techniques along with pleuripotent stem cells in order to regenerate the disc Through our previous work of injecting growth factors into disc we have been able to generate these discs in our prior studies We are trying to optimize this effect with the addition of stem cell technology to optimize the number of cells the concentration of growth factors as well as the optimal gene transfer in order to perfect the best technique to regenerate the disc We hope that this will soon move from the animal models into human trials

The Division of Sports Medicine continues to be productive in a number of research areas Our orthopaedic biomechanics lab has expanded with the addition of Daniel Boguszewski PhD Dr Boguszewski obtained his PhD from the University of Cincinnati where he developed expertise with a sophisticated robotic testing apparatus We recently acquired an industrial robot (pictured on next page) for mechanical testing and are looking forward to coupling this exciting new technique with existing techniques pioneered by Keith Markolf PhD Our bioengineers along with Drs David McAllister and Frank Petrigliano have formed a new collaboration with the UCLA Electrical Engineering Department Wireless Health initiative to develop novel ways to measure knee biomechanics and knee injury mechanisms in patients Drs McAllister and Petrigliano have established a lab at the Greater Los Angeles VA Medical Center and continue to collaborate with Ben Wu DDS PhD in the Department of

RESEARCH THE UCLA SPORTS MEDICINE PROGRAM

18

Bioengineering and Patricia Zuk PhD in the Department of Plastic Surgery on tissue engineering for ACL reconstruction and rotator cuff repair Drs Sharon Hame and David McAllister continue to participate in clinical research including outcomes of ACL reconstruction Both are co-investigators in the NIH-funded multicenter ACL Revision Surgery (MARS) study Both also continue to collect and analyze data on primary ACL reconstruction Drs Hame McAllister Gamradt and Petrigliano have all recently completed studies on the incidence of shoulder and knee procedures using the Peardiver database

19

Jeffrey Eckardt MD Professor and Chair Orthopaedic Surgery UCLA

Anthony Scaduto MD Executive Vice Chair and President and CAO LAOH

Jeffrey Wang MD Vice Chair of Clinical Operations Orthopaedic Surgery UCLA

John Adams MD Vice Chair of Research Orthopaedic Surgery UCLA

James Luck MD Residency Program Director Orthopaedic Surgery UCLAOH

FACULTY There are presently 73 faculty members in our Department of Orthopaedic Surgery

Foot and Ankle Surgery Andrea Cracchiolo III MD (Emeritus) Nelson SooHoo MD (Division Chief) Lewis Zionts MD

General Orthopaedics Peter Alexakis MD Bruce Brown MD PhD S Andrew Schwartz MD

Hand Surgery Kodi Azari MD Prosper Benhaim MD (Division Chief) Scott Mitchell MD

Joint Replacement Benjamin Bengs MD Bruce Brown MD PhD Francis Cyran MD Gerald Finerman MD Eric Johnson MD James Luck MD Bert Thomas MD (Division Chief)

Musculoskeletal Oncology Susan Bukata MD Francis Cyran MD Jeffrey Eckardt MD (Division Chief)

Osteoporosis John Adams MD Susan Bukata MD Aurelia Nattiv MD

Pediatric OrthopaedicsOrthopaedic Hospital Richard Bowen MD James Luck MD William Oppenheim MD Anthony Scaduto MD (Division Chief) Mauricio Silva MD Lewis Zionts MD

Spine SurgeryPMampR Richard Bowen MD Michael Daubs MD David Fish MD MPH (PMampR) Jae Jung MD (PMampR) Anthony Scaduto MD A Nick Shamie MD Jeffrey Wang MD (Division Chief)

Sports Medicine Richard Bowen MD Gerald Finerman MD Sharon Hame MD David McAllister MD (Division Chief) Robert Pedowitz MD PhD

Frank Petrigliano MD

Sports Medicine amp Non-Operative Orthopaedics John DiFiori MD (Division Chief) Heather Gillespie MD MPH Aurelia Nattiv MD Daniel Vigil MD

Trauma Surgery Benjamin Bengs MD Eric Farrell MD Devon Jeffcoat MD Eric Johnson MD (Division Chief)

Shriners Hospital Katherine Au MD Robert Cho MD Anna Cuomo MD Kathryn Doughty MD Colin Mosely MD Kit Song MD (Service Chief) Hugh Watts MD

VA Hospital Bruce Brown MD PhD Francis Cyran MD Sharon Hame MD Eric Johnson MD David McAllister MD Scott Mitchell MD Frank Petrigliano MD Nelson SooHoo MD (Service Chief) Bert Thomas MD Steven Zeitzew MD

Research Faculty John Adams MD (Vice Chair of Research) Maria-Grazia Ascenzi PhD Paul Bajaj PhD Fabrizio Billi PhD Daniel Boguszewski PhD Patricia Campbell PhD Daniel Cohn PhD Gay Crooks PhD Edward Ebramzadeh PhD Denis Evseenko MD PhD Eileen Fowler PhD PT Martin Hewison PhD Luisa Iruela-Arispe PhD Deborah Krakow MD Susan Krum PhD Timothy Lane PhD Philip Liu PhD Daniel Lu MD PhD Zhen Lu PhD Karen Lyons PhD Keith Markolf PhD Harry McKellop PhD Shen Pang PhD Sang-Hyun Park PhD Bruno Peault PhD Sophia Sangiorgio PhD Fu Wen Shen PhD B Chia Soo MD Kang Ting DMD Howard Winet PhD Benjamin Wu DDS PhD

20

RECENT FACULTY HONORS AND PUBLICATIONS John Adams MD

1 Vitamin D 3rd Edition Feldman DR Pike JW Adams JS eds San Diego Elsevier Press 2011

2 Chen H Gilbert LC Lu X Liu Z You S Weitzmann MN Nanes MS Adams JS Estrogen response element binding protein stimulates osteoclastogenesis and bone resorption J Bone Min Res 262537-2547 2011 PMCID PMC3417837

3 Fabri M Stenger S Shin D Yuk J Liu PT Realegeno S Lee H Krutzik SR Schenk M Sieling PA Teles R Montoya D Iyer SS Bruns H Lewinsohn DM Hollis BW Hewison M Adams JS Steinmeyer A Zuumlgel U Cheng G Jo E Bloom BR Modlin RL Vitamin D is required for IFN-γ mediated antimicrobial activity of human macrophages Sci Transl Med 3104ra102 2011 PMCID PMC3269210

4 Billi F Benya B Kavanaugh A Adams JS Ebramzadeh E McKellop H The John Charnley Award An accurate and extremely sensitive method to separate display and characterize wear debris part 1ndashpolythylene particles Clin Orthopaed Rel Res 470329-338 2012 PMCID PMC 3254734

5 James AW Pang S Askarinam A Corselli M Zara JN Goyal R Chang L Pan A Shen J Yuan W Stoker D Zhang X Adams JS Ting K Soo C Additive effects of sonic hedgehog and Nell-1 signaling in osteogenic versus adipogenic differentiation of human adipose-derived stromal cells Stem Cells Dev 212170-2178 2012 PMCID PMC3411358

Kodi Azari MD 1 Azari K Imbriglia JE Goitz RJ Shores JT Balk ML

Brandacher G Schneeberger S Gorantla V Lee WPldquoHandTransplantion The Donor and Operationrdquo Journal of Reconstructive Microsurgery (2012) 28(1) 27-34

2 Sue McDiarmid and Kodi Azari ldquoDonor Related Issues in Hand Transplantaionrdquo Hand Clinics (2011) 274 545-54

3 Tristan L Hartzell Prosper Benhaim Joeseph E Imbriglia Jaimie Shores Robert J Goitz Marshall Balk Scott Mitchell Roee Rubinstein Vijay Gorantla Stephan Schneeberger Gerald Brandacher W P Andrew LeeKodi K Azari ldquoSurgical and Technical Aspects of Hand Transplantation ndash Is it Just Another Replantrdquo Hand Clinics (2011) 274 521-30

4 Immune Modulation for Hand Transplantation Changing the Risk-Benefit Balance Brandacher G Gorantla VS Schneeberger S Shores JT Imbriglia JE Azari K Donnenberg AD Cooney DS Losee JE Lee WPA J Healthcare Science Humanities 20111(4)62-68

5 Elaine Horibe Song Afshin Shirazian Brian

Binns Yuedi Fleming Lydia M Ferreira Rod J Rohrich Kodi Azari ldquoBenchmarking academic plastic surgery services in the USrdquo Plastic and Reconstructive Surgery (2012) 129(6)1407-18

Benjamin Bengs MD

1 Bengs BC Sangiorgio SN Ebramzadeh E Achieving Clinically Adequate Stem Fixation Despite Severe Proximal Femoral Bone Loss Poster P039 Orthopedic Research Society Annual Meeting San Fransisco CA 2012

2 Sangiorgio S Knutsen A Kalma J Ebramzadeh E Bengs B Can a Dual-tapered Press-fit Stem be used in Cases with Severe Proximal Femoral Defects AAOS Poster 2043 Annual Meeting in San Francisco CA

3 Sugi M Sheridan K Lewis L Huang MH Nattiv A Kado DM BC Bengs Active referral intervention following fragility fractures leads to enhanced osteoporosis follow-up carerdquo Journal of Osteoporosis (accepted 2012)

4 Sangiorgio S Ebramzadeh E Knutsen A Kalma J Bengs B Can a Dual-tapered Press-fit Stem be used in Cases with Severe Proximal Femoral Defects Journal of Biomaterials and Biomechanics (accepted 2012)

5 Aaron W James Jia Shen Xinli Zhang Michael Chiang Asal Askarinam Raghav Goyal Alan Nguyen Janette N Zara Greg Asatrian Jonguk Chung Benjamin Bengs Cymbeline T Culiat A Simon Turner Howard B Seim III John S Adams Kang Ting Chia Soo Nell-1 Regulates Osteoblast Osteoclast Activity and Activates Wntβ-catenin Signaling A New Cause and Treatment for Osteoporosis (submitted for publication)

Prosper Benhaim MD 1 Benhaim P Anthony JP Lin LYT McCalmont TH

Mathes SJ A long-term study of allogeneic rat hindlimb transplants immunosuppressed with RS-61443 Transplantation 1993 56(4) 911-917

2 Tejwani SG Markolf KL Benhaim P Graft reconstruction of the interosseous membrane in conjunction with metallic radial head replacement a cadaveric study Journal of Hand Surgery 2005 30A(2) 335-342

3 Markolf KL Tejwani SG Benhaim P Effects of wafer resection and hemiresection from the distal ulna on load-sharing at the wrist a cadaveric study Journal of Bone and Joint Surgery 2005 30A(2) 351-358

4 Dragoo JL Lieberman JR Lee RS DeUgarte DA Lee Y Zuk PA Hedrick MH Benhaim P ldquoTissue engineered bone from BMP-2 transduced stem cells derived from human fat Plastic and Reconstructive Surgery 2005 115(6) 1665-1673

21

5 Dragoo JL Carlson G McCormick F Khan-Farooqi H Zhu M Zuk PA Benhaim P Healing full-thickness cartilage defects using adipose-derived stem cells Tissue Engineering 2007 13(7) 1615-1621

Nicholas Bernthal MD

1 Kremen TJ Jr Bernthal NM Eckardt MA Eckardt JJ Giant cell tumor of bone are we stratifying results appropriately Clin Orthop Relat Res 2012 Mar470(3)677-83

2 Bernthal NM Federman N Eilber FR Nelson SD Eckardt JJ Eilber FC Tap WD Long-term results (gt25 years) of a randomized prospective clinical trial evaluating chemotherapy in patients with high-grade operable osteosarcoma Cancer 2012 Dec 1118(23)5888-93 doi 101002cncr27651 Epub 2012 May 30

3 Pribaz JR Bernthal NM Wong TC Silva M Lateral spurring (overgrowth) after pediatric lateral condyle fractures J Pediatr Orthop 2012 Jul-Aug32(5)456-60

4 Silva M Knutsen AR Kalma JJ Borkowski SL Bernthal NM Spencer HT Sangiorgio SN Ebramzadeh E Biomechanical Testing of Pin Configurations in Supracondylar Humeral Fractures The Effect of Medial Column Comminution J Orthop Trauma 2012 Aug 28 [Epub ahead of print]

5 Niska JA Meganck JA Pribaz JR Shahbazian JH Lim E Zhang N Rice BW Akin A Ramos RI Bernthal NM Francis KP Miller LS Monitoring bacterial burden inflammation and bone damage longitudinally using optical and μCT imaging in an orthopaedic implant infection in mice PLoS One 20127(10)e47397 doi 101371journalpone0047397 Epub 2012 Oct 17

Rick Bowen MD

1 POSNA Traveling Fellowship Recipient (2008) 2 Bowen RE Scaduto AA Banuelos S Does early

thoracic fusion exacerbate preexisting restrictive lung disease in congenital scoliosis patients J Pediatr Orthop 28 506-511 2008

3 Bowen RE Scaduto AA Banuelos S Decreased body mass index and restrictive lung disease in congenital thoracic scoliosis J Pediatr Orthop 28665-8 2008

4 Bowen RE Gardner S Scaduto AA Eagan M Beckstead J Efficacy of intraoperative cell salvage systems in pediatric idiopathic scoliosis patients undergoing posterior spinal fusion with segmental spinal instrumentationSpine (Phila Pa 1976) 35246-51 2010

5 Bowen RE Knee injuries in the youth athlete Curr Orthop Prac 2012 23 422-428

Susan Bukata MD 1 Houck J Kneiss J Bukata SV Puzas JE Analysis of

vertical ground reaction force variables during a Sit to Stand task in participants recovering from a hip fracture Clin Biomech 2011 Jun 26(5) 470-6

2 Takahata M Awad HA OrsquoKeefe RJ Bukata SV Schwarz EM Endogenous tissue engineering PTH therapy for skeletal repair Cell Tissue Res 2011 May 31 [Epub ahead of print]

3 Kates SL Bukata SV DiGiovanni BF Friedman SL et al A guide to improving the care of patients with fragility fractures Geriatric Orthopaedic Surgery amp Rehabilitation 2011 2(1) 5-37

4 Sampson ER Chen D Schwarz EM Bukata SV OrsquoKeefe RJ Awad H Puzas JE Zuscik MJ Rosier RN Teriparatide as a chondro-regenerative therapy for injury-induced knee osteoarthritis Science Translational Medicine 2011 Sept 21 3(101) 101ra93

5 Kneiss JA Houck JR Bukata SV Puzas JE Influence of Upper Extremity Assistance on Lower Extremity Force Application Symmetry in Individuals Post-Hip Fracture During the Sit-to-Stand Task Journal of Orthopaedic amp Sports Physical Therapy 2012 May 42(5) 474-481

Michael Daubs MD

1 Patton CM Hung M Lawrence BD Patel A Woodbury AM Brodke DS Daubs MD Psychological Distress in a Department of Veteransrsquo Affairs Spine Patient Population The Spine J 2011 Nov 15 (epub ahead of print)

2 Daubs MD Lenke LG Kim YJ Cheh G Stobbs G Bridwell KH Does Correction of Preoperative Coronal Imbalance Make a Difference in Outcomes of Adult Deformity Patients Accepted for publication Spine June 2012

3 Daubs MD Patel AA Lawrence BD Brodke DS Excision of the Posterior Longitudinal Ligament During Anterior Cervical Corpectomy A Biomechanical Study Accepted for publication September 12 2012J Spinal Disorders

4 Daubs MD Lenke LG Cheh G Bridwell KH Kim YJ Stobbs G Decompression Alone Versus Decompression with Limited Fusion for the Treatment of Degenerative Lumbar Scoliosis in the Elderly Patient Accepted for publication Sept 5 2012Evidence Based Spine Journal

5 Tan Y Montgomery SR Aghdasi BG Inoue H Kaner T Tian H Terrell R Zhang X Wang JC Daubs MD The Effect of Corticosteroid Administration on Soft Tissue Inflammation Associated with rhBMP-2 use in a Rodent Model of Inflammation Spine (Phila Pa 1976) 2012 Nov 28 [Epub ahead of print]

16

support and teamwork contributed by the Broad Stem Cell Institute the Jonsson Comprehensive Cancer Center the Department of Molecular Cell and Developmental Biology in the UCLA College of Letters and Science and the Clinical and Translational Science Institute

The Orthopaedic Hospital Research Center on the Westwood campus provides a fertile environment for our researchers

and clinicians to innovate and collaborate in pediatric orthopaedic science Karen Lyons PhD has received international awards for her breakthrough work in skeletal development and growth-plate biology while Deborah Krakow MD and Dan Cohn PhD (both pictured above) have identified several key genetic mutations that cause dwarfism These discoveries have lead to a better understanding of bone diseases that affect children and are the basis for novel future treatments Our clinicians and scientists are also focused on translational research that enhances orthopaedic treatment for children by improving surgical techniques and non-surgical care In collaboration with the pediatric spine surgeons Sophia Sangiorgio PhD and Edward Ebramzadeh PhD have developed an experimental model to test and compare surgical techniques used in scoliosis surgery Their work will be presented at this yearrsquos Scoliosis Research Society meeting Mauricio Silva MD maintains one of the largest prospective pediatric trauma registries in the country The analysis of this database has resulted in several recent JBJS publications that are likely to shape the evidence-based treatment of pediatric elbow fractures He and Fabrizio Billi PhD are also collaborating with scientists in UCLArsquos School of Engineering to develop a wireless technology that can improve the fit and function of casts used to treat childrenrsquos fractures In the field of motor disorders Eileen Fowler PhD PT (pictured) and

her team have recently developed and validated a method to measure selective motor control that can predict the success of surgery for patients with cerebral palsy We are proud of the

UCLAOrthopaedic Hospital partnership and the significant contributions our pediatric orthopaedic clinicians and scientists have made We look forward to further advances that help children overcome their musculoskeletal injuries and disease The Orthopaedic Hospital Research Center remains dedicated to its founding principles First that major advances in understanding the pathobiology and management of those diseases that are most frequently encountered by the practicing orthopaedic surgeon (eg fractures joint instability etc) can be best achieved by teams of scientists with expertise ranging from molecular biology to clinical care of patients Second understanding the developmental events that shape formation of the musculoskeletal system from fetal to adult life will inform us about the deconstruction of the system that happens with aging and disease Third that development of mouse models of common human orthopaedic disease where genes in the mouse can be ldquoknocked outrdquo or amplified will allow us to develop ldquopersonalized-rdquo molecularly-targeted preventative and treatment regimens Finally by bringing the cadre of clinician-scientists into a

17

common practice setting in the new Orthopaedic Hospital in at the Santa Monica-UCLA Medical Center and Orthopaedic Hospital we hope to translate basic discoveries made in the Orthopaedic Hospital Research Center to a new standard of orthopaedic health care for both children and adults

Another study is focusing on bone formation as well as spinal fusion We are utilizing bone graft substitutes along with the appropriate growth factors to optimize the healing of the spinal fusions through the least amount of invasiveness with minimally invasive techniques Our previous studies have shown that with gene therapy we have been able to achieve spinal fusion in a very efficient manner We hope to optimize this with

the use of new bone graft materials with new growth factors in order to obtain 100 spinal fusion ultimately for our patients We hope to start clinical trials in this soon Another study we are looking at is the suppression of tumors One of the growth factors that we have invented in our laboratory here at UCLA has shown an effect to inhibit BMP bone morphogenic growth factors many tumors rely on to grow We have shown the addition of this novel growth factor can suppress the growth of tumor cells We have initiated a project where we are attempting to use this novel protein to inhibit the growth of tumors We ultimately hope that this will act as a new therapeutic method in the fight against cancer A new technology of dynamic MRI imaging will allow us to identify the pathology for patients with spine problems We have previously published over 18 scientific articles looking at the effect of dynamic motion MRI in identifying spinal pathology We are perfecting this technique and hope to institute this as a part of our standard treatment protocol for patients with spinal problems

RESEARCH THE UCLA SPINE PROGRAM The Spine Service continues to explore new areas in both basic science and clinical research in the area of spinal disorders We have a world-class laboratory that continues to attract surgeons on an international level to come and participate in our research efforts We have seven ongoing international fellowships for surgeons to come and collaborate on our research projects One of our publications was named the outstanding paper award this past year by The Spine Journal We recently received an OREF (Orthopaedic Research and Education Foundation) grant for starting a biologics registry for spinal fusion Our basic science efforts encompass several novel projects for regeneration of the spinal tissuesdiscs We are utilizing the most novel gene therapy transfer techniques along with pleuripotent stem cells in order to regenerate the disc Through our previous work of injecting growth factors into disc we have been able to generate these discs in our prior studies We are trying to optimize this effect with the addition of stem cell technology to optimize the number of cells the concentration of growth factors as well as the optimal gene transfer in order to perfect the best technique to regenerate the disc We hope that this will soon move from the animal models into human trials

The Division of Sports Medicine continues to be productive in a number of research areas Our orthopaedic biomechanics lab has expanded with the addition of Daniel Boguszewski PhD Dr Boguszewski obtained his PhD from the University of Cincinnati where he developed expertise with a sophisticated robotic testing apparatus We recently acquired an industrial robot (pictured on next page) for mechanical testing and are looking forward to coupling this exciting new technique with existing techniques pioneered by Keith Markolf PhD Our bioengineers along with Drs David McAllister and Frank Petrigliano have formed a new collaboration with the UCLA Electrical Engineering Department Wireless Health initiative to develop novel ways to measure knee biomechanics and knee injury mechanisms in patients Drs McAllister and Petrigliano have established a lab at the Greater Los Angeles VA Medical Center and continue to collaborate with Ben Wu DDS PhD in the Department of

RESEARCH THE UCLA SPORTS MEDICINE PROGRAM

18

Bioengineering and Patricia Zuk PhD in the Department of Plastic Surgery on tissue engineering for ACL reconstruction and rotator cuff repair Drs Sharon Hame and David McAllister continue to participate in clinical research including outcomes of ACL reconstruction Both are co-investigators in the NIH-funded multicenter ACL Revision Surgery (MARS) study Both also continue to collect and analyze data on primary ACL reconstruction Drs Hame McAllister Gamradt and Petrigliano have all recently completed studies on the incidence of shoulder and knee procedures using the Peardiver database

19

Jeffrey Eckardt MD Professor and Chair Orthopaedic Surgery UCLA

Anthony Scaduto MD Executive Vice Chair and President and CAO LAOH

Jeffrey Wang MD Vice Chair of Clinical Operations Orthopaedic Surgery UCLA

John Adams MD Vice Chair of Research Orthopaedic Surgery UCLA

James Luck MD Residency Program Director Orthopaedic Surgery UCLAOH

FACULTY There are presently 73 faculty members in our Department of Orthopaedic Surgery

Foot and Ankle Surgery Andrea Cracchiolo III MD (Emeritus) Nelson SooHoo MD (Division Chief) Lewis Zionts MD

General Orthopaedics Peter Alexakis MD Bruce Brown MD PhD S Andrew Schwartz MD

Hand Surgery Kodi Azari MD Prosper Benhaim MD (Division Chief) Scott Mitchell MD

Joint Replacement Benjamin Bengs MD Bruce Brown MD PhD Francis Cyran MD Gerald Finerman MD Eric Johnson MD James Luck MD Bert Thomas MD (Division Chief)

Musculoskeletal Oncology Susan Bukata MD Francis Cyran MD Jeffrey Eckardt MD (Division Chief)

Osteoporosis John Adams MD Susan Bukata MD Aurelia Nattiv MD

Pediatric OrthopaedicsOrthopaedic Hospital Richard Bowen MD James Luck MD William Oppenheim MD Anthony Scaduto MD (Division Chief) Mauricio Silva MD Lewis Zionts MD

Spine SurgeryPMampR Richard Bowen MD Michael Daubs MD David Fish MD MPH (PMampR) Jae Jung MD (PMampR) Anthony Scaduto MD A Nick Shamie MD Jeffrey Wang MD (Division Chief)

Sports Medicine Richard Bowen MD Gerald Finerman MD Sharon Hame MD David McAllister MD (Division Chief) Robert Pedowitz MD PhD

Frank Petrigliano MD

Sports Medicine amp Non-Operative Orthopaedics John DiFiori MD (Division Chief) Heather Gillespie MD MPH Aurelia Nattiv MD Daniel Vigil MD

Trauma Surgery Benjamin Bengs MD Eric Farrell MD Devon Jeffcoat MD Eric Johnson MD (Division Chief)

Shriners Hospital Katherine Au MD Robert Cho MD Anna Cuomo MD Kathryn Doughty MD Colin Mosely MD Kit Song MD (Service Chief) Hugh Watts MD

VA Hospital Bruce Brown MD PhD Francis Cyran MD Sharon Hame MD Eric Johnson MD David McAllister MD Scott Mitchell MD Frank Petrigliano MD Nelson SooHoo MD (Service Chief) Bert Thomas MD Steven Zeitzew MD

Research Faculty John Adams MD (Vice Chair of Research) Maria-Grazia Ascenzi PhD Paul Bajaj PhD Fabrizio Billi PhD Daniel Boguszewski PhD Patricia Campbell PhD Daniel Cohn PhD Gay Crooks PhD Edward Ebramzadeh PhD Denis Evseenko MD PhD Eileen Fowler PhD PT Martin Hewison PhD Luisa Iruela-Arispe PhD Deborah Krakow MD Susan Krum PhD Timothy Lane PhD Philip Liu PhD Daniel Lu MD PhD Zhen Lu PhD Karen Lyons PhD Keith Markolf PhD Harry McKellop PhD Shen Pang PhD Sang-Hyun Park PhD Bruno Peault PhD Sophia Sangiorgio PhD Fu Wen Shen PhD B Chia Soo MD Kang Ting DMD Howard Winet PhD Benjamin Wu DDS PhD

20

RECENT FACULTY HONORS AND PUBLICATIONS John Adams MD

1 Vitamin D 3rd Edition Feldman DR Pike JW Adams JS eds San Diego Elsevier Press 2011

2 Chen H Gilbert LC Lu X Liu Z You S Weitzmann MN Nanes MS Adams JS Estrogen response element binding protein stimulates osteoclastogenesis and bone resorption J Bone Min Res 262537-2547 2011 PMCID PMC3417837

3 Fabri M Stenger S Shin D Yuk J Liu PT Realegeno S Lee H Krutzik SR Schenk M Sieling PA Teles R Montoya D Iyer SS Bruns H Lewinsohn DM Hollis BW Hewison M Adams JS Steinmeyer A Zuumlgel U Cheng G Jo E Bloom BR Modlin RL Vitamin D is required for IFN-γ mediated antimicrobial activity of human macrophages Sci Transl Med 3104ra102 2011 PMCID PMC3269210

4 Billi F Benya B Kavanaugh A Adams JS Ebramzadeh E McKellop H The John Charnley Award An accurate and extremely sensitive method to separate display and characterize wear debris part 1ndashpolythylene particles Clin Orthopaed Rel Res 470329-338 2012 PMCID PMC 3254734

5 James AW Pang S Askarinam A Corselli M Zara JN Goyal R Chang L Pan A Shen J Yuan W Stoker D Zhang X Adams JS Ting K Soo C Additive effects of sonic hedgehog and Nell-1 signaling in osteogenic versus adipogenic differentiation of human adipose-derived stromal cells Stem Cells Dev 212170-2178 2012 PMCID PMC3411358

Kodi Azari MD 1 Azari K Imbriglia JE Goitz RJ Shores JT Balk ML

Brandacher G Schneeberger S Gorantla V Lee WPldquoHandTransplantion The Donor and Operationrdquo Journal of Reconstructive Microsurgery (2012) 28(1) 27-34

2 Sue McDiarmid and Kodi Azari ldquoDonor Related Issues in Hand Transplantaionrdquo Hand Clinics (2011) 274 545-54

3 Tristan L Hartzell Prosper Benhaim Joeseph E Imbriglia Jaimie Shores Robert J Goitz Marshall Balk Scott Mitchell Roee Rubinstein Vijay Gorantla Stephan Schneeberger Gerald Brandacher W P Andrew LeeKodi K Azari ldquoSurgical and Technical Aspects of Hand Transplantation ndash Is it Just Another Replantrdquo Hand Clinics (2011) 274 521-30

4 Immune Modulation for Hand Transplantation Changing the Risk-Benefit Balance Brandacher G Gorantla VS Schneeberger S Shores JT Imbriglia JE Azari K Donnenberg AD Cooney DS Losee JE Lee WPA J Healthcare Science Humanities 20111(4)62-68

5 Elaine Horibe Song Afshin Shirazian Brian

Binns Yuedi Fleming Lydia M Ferreira Rod J Rohrich Kodi Azari ldquoBenchmarking academic plastic surgery services in the USrdquo Plastic and Reconstructive Surgery (2012) 129(6)1407-18

Benjamin Bengs MD

1 Bengs BC Sangiorgio SN Ebramzadeh E Achieving Clinically Adequate Stem Fixation Despite Severe Proximal Femoral Bone Loss Poster P039 Orthopedic Research Society Annual Meeting San Fransisco CA 2012

2 Sangiorgio S Knutsen A Kalma J Ebramzadeh E Bengs B Can a Dual-tapered Press-fit Stem be used in Cases with Severe Proximal Femoral Defects AAOS Poster 2043 Annual Meeting in San Francisco CA

3 Sugi M Sheridan K Lewis L Huang MH Nattiv A Kado DM BC Bengs Active referral intervention following fragility fractures leads to enhanced osteoporosis follow-up carerdquo Journal of Osteoporosis (accepted 2012)

4 Sangiorgio S Ebramzadeh E Knutsen A Kalma J Bengs B Can a Dual-tapered Press-fit Stem be used in Cases with Severe Proximal Femoral Defects Journal of Biomaterials and Biomechanics (accepted 2012)

5 Aaron W James Jia Shen Xinli Zhang Michael Chiang Asal Askarinam Raghav Goyal Alan Nguyen Janette N Zara Greg Asatrian Jonguk Chung Benjamin Bengs Cymbeline T Culiat A Simon Turner Howard B Seim III John S Adams Kang Ting Chia Soo Nell-1 Regulates Osteoblast Osteoclast Activity and Activates Wntβ-catenin Signaling A New Cause and Treatment for Osteoporosis (submitted for publication)

Prosper Benhaim MD 1 Benhaim P Anthony JP Lin LYT McCalmont TH

Mathes SJ A long-term study of allogeneic rat hindlimb transplants immunosuppressed with RS-61443 Transplantation 1993 56(4) 911-917

2 Tejwani SG Markolf KL Benhaim P Graft reconstruction of the interosseous membrane in conjunction with metallic radial head replacement a cadaveric study Journal of Hand Surgery 2005 30A(2) 335-342

3 Markolf KL Tejwani SG Benhaim P Effects of wafer resection and hemiresection from the distal ulna on load-sharing at the wrist a cadaveric study Journal of Bone and Joint Surgery 2005 30A(2) 351-358

4 Dragoo JL Lieberman JR Lee RS DeUgarte DA Lee Y Zuk PA Hedrick MH Benhaim P ldquoTissue engineered bone from BMP-2 transduced stem cells derived from human fat Plastic and Reconstructive Surgery 2005 115(6) 1665-1673

21

5 Dragoo JL Carlson G McCormick F Khan-Farooqi H Zhu M Zuk PA Benhaim P Healing full-thickness cartilage defects using adipose-derived stem cells Tissue Engineering 2007 13(7) 1615-1621

Nicholas Bernthal MD

1 Kremen TJ Jr Bernthal NM Eckardt MA Eckardt JJ Giant cell tumor of bone are we stratifying results appropriately Clin Orthop Relat Res 2012 Mar470(3)677-83

2 Bernthal NM Federman N Eilber FR Nelson SD Eckardt JJ Eilber FC Tap WD Long-term results (gt25 years) of a randomized prospective clinical trial evaluating chemotherapy in patients with high-grade operable osteosarcoma Cancer 2012 Dec 1118(23)5888-93 doi 101002cncr27651 Epub 2012 May 30

3 Pribaz JR Bernthal NM Wong TC Silva M Lateral spurring (overgrowth) after pediatric lateral condyle fractures J Pediatr Orthop 2012 Jul-Aug32(5)456-60

4 Silva M Knutsen AR Kalma JJ Borkowski SL Bernthal NM Spencer HT Sangiorgio SN Ebramzadeh E Biomechanical Testing of Pin Configurations in Supracondylar Humeral Fractures The Effect of Medial Column Comminution J Orthop Trauma 2012 Aug 28 [Epub ahead of print]

5 Niska JA Meganck JA Pribaz JR Shahbazian JH Lim E Zhang N Rice BW Akin A Ramos RI Bernthal NM Francis KP Miller LS Monitoring bacterial burden inflammation and bone damage longitudinally using optical and μCT imaging in an orthopaedic implant infection in mice PLoS One 20127(10)e47397 doi 101371journalpone0047397 Epub 2012 Oct 17

Rick Bowen MD

1 POSNA Traveling Fellowship Recipient (2008) 2 Bowen RE Scaduto AA Banuelos S Does early

thoracic fusion exacerbate preexisting restrictive lung disease in congenital scoliosis patients J Pediatr Orthop 28 506-511 2008

3 Bowen RE Scaduto AA Banuelos S Decreased body mass index and restrictive lung disease in congenital thoracic scoliosis J Pediatr Orthop 28665-8 2008

4 Bowen RE Gardner S Scaduto AA Eagan M Beckstead J Efficacy of intraoperative cell salvage systems in pediatric idiopathic scoliosis patients undergoing posterior spinal fusion with segmental spinal instrumentationSpine (Phila Pa 1976) 35246-51 2010

5 Bowen RE Knee injuries in the youth athlete Curr Orthop Prac 2012 23 422-428

Susan Bukata MD 1 Houck J Kneiss J Bukata SV Puzas JE Analysis of

vertical ground reaction force variables during a Sit to Stand task in participants recovering from a hip fracture Clin Biomech 2011 Jun 26(5) 470-6

2 Takahata M Awad HA OrsquoKeefe RJ Bukata SV Schwarz EM Endogenous tissue engineering PTH therapy for skeletal repair Cell Tissue Res 2011 May 31 [Epub ahead of print]

3 Kates SL Bukata SV DiGiovanni BF Friedman SL et al A guide to improving the care of patients with fragility fractures Geriatric Orthopaedic Surgery amp Rehabilitation 2011 2(1) 5-37

4 Sampson ER Chen D Schwarz EM Bukata SV OrsquoKeefe RJ Awad H Puzas JE Zuscik MJ Rosier RN Teriparatide as a chondro-regenerative therapy for injury-induced knee osteoarthritis Science Translational Medicine 2011 Sept 21 3(101) 101ra93

5 Kneiss JA Houck JR Bukata SV Puzas JE Influence of Upper Extremity Assistance on Lower Extremity Force Application Symmetry in Individuals Post-Hip Fracture During the Sit-to-Stand Task Journal of Orthopaedic amp Sports Physical Therapy 2012 May 42(5) 474-481

Michael Daubs MD

1 Patton CM Hung M Lawrence BD Patel A Woodbury AM Brodke DS Daubs MD Psychological Distress in a Department of Veteransrsquo Affairs Spine Patient Population The Spine J 2011 Nov 15 (epub ahead of print)

2 Daubs MD Lenke LG Kim YJ Cheh G Stobbs G Bridwell KH Does Correction of Preoperative Coronal Imbalance Make a Difference in Outcomes of Adult Deformity Patients Accepted for publication Spine June 2012

3 Daubs MD Patel AA Lawrence BD Brodke DS Excision of the Posterior Longitudinal Ligament During Anterior Cervical Corpectomy A Biomechanical Study Accepted for publication September 12 2012J Spinal Disorders

4 Daubs MD Lenke LG Cheh G Bridwell KH Kim YJ Stobbs G Decompression Alone Versus Decompression with Limited Fusion for the Treatment of Degenerative Lumbar Scoliosis in the Elderly Patient Accepted for publication Sept 5 2012Evidence Based Spine Journal

5 Tan Y Montgomery SR Aghdasi BG Inoue H Kaner T Tian H Terrell R Zhang X Wang JC Daubs MD The Effect of Corticosteroid Administration on Soft Tissue Inflammation Associated with rhBMP-2 use in a Rodent Model of Inflammation Spine (Phila Pa 1976) 2012 Nov 28 [Epub ahead of print]

17

common practice setting in the new Orthopaedic Hospital in at the Santa Monica-UCLA Medical Center and Orthopaedic Hospital we hope to translate basic discoveries made in the Orthopaedic Hospital Research Center to a new standard of orthopaedic health care for both children and adults

Another study is focusing on bone formation as well as spinal fusion We are utilizing bone graft substitutes along with the appropriate growth factors to optimize the healing of the spinal fusions through the least amount of invasiveness with minimally invasive techniques Our previous studies have shown that with gene therapy we have been able to achieve spinal fusion in a very efficient manner We hope to optimize this with

the use of new bone graft materials with new growth factors in order to obtain 100 spinal fusion ultimately for our patients We hope to start clinical trials in this soon Another study we are looking at is the suppression of tumors One of the growth factors that we have invented in our laboratory here at UCLA has shown an effect to inhibit BMP bone morphogenic growth factors many tumors rely on to grow We have shown the addition of this novel growth factor can suppress the growth of tumor cells We have initiated a project where we are attempting to use this novel protein to inhibit the growth of tumors We ultimately hope that this will act as a new therapeutic method in the fight against cancer A new technology of dynamic MRI imaging will allow us to identify the pathology for patients with spine problems We have previously published over 18 scientific articles looking at the effect of dynamic motion MRI in identifying spinal pathology We are perfecting this technique and hope to institute this as a part of our standard treatment protocol for patients with spinal problems

RESEARCH THE UCLA SPINE PROGRAM The Spine Service continues to explore new areas in both basic science and clinical research in the area of spinal disorders We have a world-class laboratory that continues to attract surgeons on an international level to come and participate in our research efforts We have seven ongoing international fellowships for surgeons to come and collaborate on our research projects One of our publications was named the outstanding paper award this past year by The Spine Journal We recently received an OREF (Orthopaedic Research and Education Foundation) grant for starting a biologics registry for spinal fusion Our basic science efforts encompass several novel projects for regeneration of the spinal tissuesdiscs We are utilizing the most novel gene therapy transfer techniques along with pleuripotent stem cells in order to regenerate the disc Through our previous work of injecting growth factors into disc we have been able to generate these discs in our prior studies We are trying to optimize this effect with the addition of stem cell technology to optimize the number of cells the concentration of growth factors as well as the optimal gene transfer in order to perfect the best technique to regenerate the disc We hope that this will soon move from the animal models into human trials

The Division of Sports Medicine continues to be productive in a number of research areas Our orthopaedic biomechanics lab has expanded with the addition of Daniel Boguszewski PhD Dr Boguszewski obtained his PhD from the University of Cincinnati where he developed expertise with a sophisticated robotic testing apparatus We recently acquired an industrial robot (pictured on next page) for mechanical testing and are looking forward to coupling this exciting new technique with existing techniques pioneered by Keith Markolf PhD Our bioengineers along with Drs David McAllister and Frank Petrigliano have formed a new collaboration with the UCLA Electrical Engineering Department Wireless Health initiative to develop novel ways to measure knee biomechanics and knee injury mechanisms in patients Drs McAllister and Petrigliano have established a lab at the Greater Los Angeles VA Medical Center and continue to collaborate with Ben Wu DDS PhD in the Department of

RESEARCH THE UCLA SPORTS MEDICINE PROGRAM

18

Bioengineering and Patricia Zuk PhD in the Department of Plastic Surgery on tissue engineering for ACL reconstruction and rotator cuff repair Drs Sharon Hame and David McAllister continue to participate in clinical research including outcomes of ACL reconstruction Both are co-investigators in the NIH-funded multicenter ACL Revision Surgery (MARS) study Both also continue to collect and analyze data on primary ACL reconstruction Drs Hame McAllister Gamradt and Petrigliano have all recently completed studies on the incidence of shoulder and knee procedures using the Peardiver database

19

Jeffrey Eckardt MD Professor and Chair Orthopaedic Surgery UCLA

Anthony Scaduto MD Executive Vice Chair and President and CAO LAOH

Jeffrey Wang MD Vice Chair of Clinical Operations Orthopaedic Surgery UCLA

John Adams MD Vice Chair of Research Orthopaedic Surgery UCLA

James Luck MD Residency Program Director Orthopaedic Surgery UCLAOH

FACULTY There are presently 73 faculty members in our Department of Orthopaedic Surgery

Foot and Ankle Surgery Andrea Cracchiolo III MD (Emeritus) Nelson SooHoo MD (Division Chief) Lewis Zionts MD

General Orthopaedics Peter Alexakis MD Bruce Brown MD PhD S Andrew Schwartz MD

Hand Surgery Kodi Azari MD Prosper Benhaim MD (Division Chief) Scott Mitchell MD

Joint Replacement Benjamin Bengs MD Bruce Brown MD PhD Francis Cyran MD Gerald Finerman MD Eric Johnson MD James Luck MD Bert Thomas MD (Division Chief)

Musculoskeletal Oncology Susan Bukata MD Francis Cyran MD Jeffrey Eckardt MD (Division Chief)

Osteoporosis John Adams MD Susan Bukata MD Aurelia Nattiv MD

Pediatric OrthopaedicsOrthopaedic Hospital Richard Bowen MD James Luck MD William Oppenheim MD Anthony Scaduto MD (Division Chief) Mauricio Silva MD Lewis Zionts MD

Spine SurgeryPMampR Richard Bowen MD Michael Daubs MD David Fish MD MPH (PMampR) Jae Jung MD (PMampR) Anthony Scaduto MD A Nick Shamie MD Jeffrey Wang MD (Division Chief)

Sports Medicine Richard Bowen MD Gerald Finerman MD Sharon Hame MD David McAllister MD (Division Chief) Robert Pedowitz MD PhD

Frank Petrigliano MD

Sports Medicine amp Non-Operative Orthopaedics John DiFiori MD (Division Chief) Heather Gillespie MD MPH Aurelia Nattiv MD Daniel Vigil MD

Trauma Surgery Benjamin Bengs MD Eric Farrell MD Devon Jeffcoat MD Eric Johnson MD (Division Chief)

Shriners Hospital Katherine Au MD Robert Cho MD Anna Cuomo MD Kathryn Doughty MD Colin Mosely MD Kit Song MD (Service Chief) Hugh Watts MD

VA Hospital Bruce Brown MD PhD Francis Cyran MD Sharon Hame MD Eric Johnson MD David McAllister MD Scott Mitchell MD Frank Petrigliano MD Nelson SooHoo MD (Service Chief) Bert Thomas MD Steven Zeitzew MD

Research Faculty John Adams MD (Vice Chair of Research) Maria-Grazia Ascenzi PhD Paul Bajaj PhD Fabrizio Billi PhD Daniel Boguszewski PhD Patricia Campbell PhD Daniel Cohn PhD Gay Crooks PhD Edward Ebramzadeh PhD Denis Evseenko MD PhD Eileen Fowler PhD PT Martin Hewison PhD Luisa Iruela-Arispe PhD Deborah Krakow MD Susan Krum PhD Timothy Lane PhD Philip Liu PhD Daniel Lu MD PhD Zhen Lu PhD Karen Lyons PhD Keith Markolf PhD Harry McKellop PhD Shen Pang PhD Sang-Hyun Park PhD Bruno Peault PhD Sophia Sangiorgio PhD Fu Wen Shen PhD B Chia Soo MD Kang Ting DMD Howard Winet PhD Benjamin Wu DDS PhD

20

RECENT FACULTY HONORS AND PUBLICATIONS John Adams MD

1 Vitamin D 3rd Edition Feldman DR Pike JW Adams JS eds San Diego Elsevier Press 2011

2 Chen H Gilbert LC Lu X Liu Z You S Weitzmann MN Nanes MS Adams JS Estrogen response element binding protein stimulates osteoclastogenesis and bone resorption J Bone Min Res 262537-2547 2011 PMCID PMC3417837

3 Fabri M Stenger S Shin D Yuk J Liu PT Realegeno S Lee H Krutzik SR Schenk M Sieling PA Teles R Montoya D Iyer SS Bruns H Lewinsohn DM Hollis BW Hewison M Adams JS Steinmeyer A Zuumlgel U Cheng G Jo E Bloom BR Modlin RL Vitamin D is required for IFN-γ mediated antimicrobial activity of human macrophages Sci Transl Med 3104ra102 2011 PMCID PMC3269210

4 Billi F Benya B Kavanaugh A Adams JS Ebramzadeh E McKellop H The John Charnley Award An accurate and extremely sensitive method to separate display and characterize wear debris part 1ndashpolythylene particles Clin Orthopaed Rel Res 470329-338 2012 PMCID PMC 3254734

5 James AW Pang S Askarinam A Corselli M Zara JN Goyal R Chang L Pan A Shen J Yuan W Stoker D Zhang X Adams JS Ting K Soo C Additive effects of sonic hedgehog and Nell-1 signaling in osteogenic versus adipogenic differentiation of human adipose-derived stromal cells Stem Cells Dev 212170-2178 2012 PMCID PMC3411358

Kodi Azari MD 1 Azari K Imbriglia JE Goitz RJ Shores JT Balk ML

Brandacher G Schneeberger S Gorantla V Lee WPldquoHandTransplantion The Donor and Operationrdquo Journal of Reconstructive Microsurgery (2012) 28(1) 27-34

2 Sue McDiarmid and Kodi Azari ldquoDonor Related Issues in Hand Transplantaionrdquo Hand Clinics (2011) 274 545-54

3 Tristan L Hartzell Prosper Benhaim Joeseph E Imbriglia Jaimie Shores Robert J Goitz Marshall Balk Scott Mitchell Roee Rubinstein Vijay Gorantla Stephan Schneeberger Gerald Brandacher W P Andrew LeeKodi K Azari ldquoSurgical and Technical Aspects of Hand Transplantation ndash Is it Just Another Replantrdquo Hand Clinics (2011) 274 521-30

4 Immune Modulation for Hand Transplantation Changing the Risk-Benefit Balance Brandacher G Gorantla VS Schneeberger S Shores JT Imbriglia JE Azari K Donnenberg AD Cooney DS Losee JE Lee WPA J Healthcare Science Humanities 20111(4)62-68

5 Elaine Horibe Song Afshin Shirazian Brian

Binns Yuedi Fleming Lydia M Ferreira Rod J Rohrich Kodi Azari ldquoBenchmarking academic plastic surgery services in the USrdquo Plastic and Reconstructive Surgery (2012) 129(6)1407-18

Benjamin Bengs MD

1 Bengs BC Sangiorgio SN Ebramzadeh E Achieving Clinically Adequate Stem Fixation Despite Severe Proximal Femoral Bone Loss Poster P039 Orthopedic Research Society Annual Meeting San Fransisco CA 2012

2 Sangiorgio S Knutsen A Kalma J Ebramzadeh E Bengs B Can a Dual-tapered Press-fit Stem be used in Cases with Severe Proximal Femoral Defects AAOS Poster 2043 Annual Meeting in San Francisco CA

3 Sugi M Sheridan K Lewis L Huang MH Nattiv A Kado DM BC Bengs Active referral intervention following fragility fractures leads to enhanced osteoporosis follow-up carerdquo Journal of Osteoporosis (accepted 2012)

4 Sangiorgio S Ebramzadeh E Knutsen A Kalma J Bengs B Can a Dual-tapered Press-fit Stem be used in Cases with Severe Proximal Femoral Defects Journal of Biomaterials and Biomechanics (accepted 2012)

5 Aaron W James Jia Shen Xinli Zhang Michael Chiang Asal Askarinam Raghav Goyal Alan Nguyen Janette N Zara Greg Asatrian Jonguk Chung Benjamin Bengs Cymbeline T Culiat A Simon Turner Howard B Seim III John S Adams Kang Ting Chia Soo Nell-1 Regulates Osteoblast Osteoclast Activity and Activates Wntβ-catenin Signaling A New Cause and Treatment for Osteoporosis (submitted for publication)

Prosper Benhaim MD 1 Benhaim P Anthony JP Lin LYT McCalmont TH

Mathes SJ A long-term study of allogeneic rat hindlimb transplants immunosuppressed with RS-61443 Transplantation 1993 56(4) 911-917

2 Tejwani SG Markolf KL Benhaim P Graft reconstruction of the interosseous membrane in conjunction with metallic radial head replacement a cadaveric study Journal of Hand Surgery 2005 30A(2) 335-342

3 Markolf KL Tejwani SG Benhaim P Effects of wafer resection and hemiresection from the distal ulna on load-sharing at the wrist a cadaveric study Journal of Bone and Joint Surgery 2005 30A(2) 351-358

4 Dragoo JL Lieberman JR Lee RS DeUgarte DA Lee Y Zuk PA Hedrick MH Benhaim P ldquoTissue engineered bone from BMP-2 transduced stem cells derived from human fat Plastic and Reconstructive Surgery 2005 115(6) 1665-1673

21

5 Dragoo JL Carlson G McCormick F Khan-Farooqi H Zhu M Zuk PA Benhaim P Healing full-thickness cartilage defects using adipose-derived stem cells Tissue Engineering 2007 13(7) 1615-1621

Nicholas Bernthal MD

1 Kremen TJ Jr Bernthal NM Eckardt MA Eckardt JJ Giant cell tumor of bone are we stratifying results appropriately Clin Orthop Relat Res 2012 Mar470(3)677-83

2 Bernthal NM Federman N Eilber FR Nelson SD Eckardt JJ Eilber FC Tap WD Long-term results (gt25 years) of a randomized prospective clinical trial evaluating chemotherapy in patients with high-grade operable osteosarcoma Cancer 2012 Dec 1118(23)5888-93 doi 101002cncr27651 Epub 2012 May 30

3 Pribaz JR Bernthal NM Wong TC Silva M Lateral spurring (overgrowth) after pediatric lateral condyle fractures J Pediatr Orthop 2012 Jul-Aug32(5)456-60

4 Silva M Knutsen AR Kalma JJ Borkowski SL Bernthal NM Spencer HT Sangiorgio SN Ebramzadeh E Biomechanical Testing of Pin Configurations in Supracondylar Humeral Fractures The Effect of Medial Column Comminution J Orthop Trauma 2012 Aug 28 [Epub ahead of print]

5 Niska JA Meganck JA Pribaz JR Shahbazian JH Lim E Zhang N Rice BW Akin A Ramos RI Bernthal NM Francis KP Miller LS Monitoring bacterial burden inflammation and bone damage longitudinally using optical and μCT imaging in an orthopaedic implant infection in mice PLoS One 20127(10)e47397 doi 101371journalpone0047397 Epub 2012 Oct 17

Rick Bowen MD

1 POSNA Traveling Fellowship Recipient (2008) 2 Bowen RE Scaduto AA Banuelos S Does early

thoracic fusion exacerbate preexisting restrictive lung disease in congenital scoliosis patients J Pediatr Orthop 28 506-511 2008

3 Bowen RE Scaduto AA Banuelos S Decreased body mass index and restrictive lung disease in congenital thoracic scoliosis J Pediatr Orthop 28665-8 2008

4 Bowen RE Gardner S Scaduto AA Eagan M Beckstead J Efficacy of intraoperative cell salvage systems in pediatric idiopathic scoliosis patients undergoing posterior spinal fusion with segmental spinal instrumentationSpine (Phila Pa 1976) 35246-51 2010

5 Bowen RE Knee injuries in the youth athlete Curr Orthop Prac 2012 23 422-428

Susan Bukata MD 1 Houck J Kneiss J Bukata SV Puzas JE Analysis of

vertical ground reaction force variables during a Sit to Stand task in participants recovering from a hip fracture Clin Biomech 2011 Jun 26(5) 470-6

2 Takahata M Awad HA OrsquoKeefe RJ Bukata SV Schwarz EM Endogenous tissue engineering PTH therapy for skeletal repair Cell Tissue Res 2011 May 31 [Epub ahead of print]

3 Kates SL Bukata SV DiGiovanni BF Friedman SL et al A guide to improving the care of patients with fragility fractures Geriatric Orthopaedic Surgery amp Rehabilitation 2011 2(1) 5-37

4 Sampson ER Chen D Schwarz EM Bukata SV OrsquoKeefe RJ Awad H Puzas JE Zuscik MJ Rosier RN Teriparatide as a chondro-regenerative therapy for injury-induced knee osteoarthritis Science Translational Medicine 2011 Sept 21 3(101) 101ra93

5 Kneiss JA Houck JR Bukata SV Puzas JE Influence of Upper Extremity Assistance on Lower Extremity Force Application Symmetry in Individuals Post-Hip Fracture During the Sit-to-Stand Task Journal of Orthopaedic amp Sports Physical Therapy 2012 May 42(5) 474-481

Michael Daubs MD

1 Patton CM Hung M Lawrence BD Patel A Woodbury AM Brodke DS Daubs MD Psychological Distress in a Department of Veteransrsquo Affairs Spine Patient Population The Spine J 2011 Nov 15 (epub ahead of print)

2 Daubs MD Lenke LG Kim YJ Cheh G Stobbs G Bridwell KH Does Correction of Preoperative Coronal Imbalance Make a Difference in Outcomes of Adult Deformity Patients Accepted for publication Spine June 2012

3 Daubs MD Patel AA Lawrence BD Brodke DS Excision of the Posterior Longitudinal Ligament During Anterior Cervical Corpectomy A Biomechanical Study Accepted for publication September 12 2012J Spinal Disorders

4 Daubs MD Lenke LG Cheh G Bridwell KH Kim YJ Stobbs G Decompression Alone Versus Decompression with Limited Fusion for the Treatment of Degenerative Lumbar Scoliosis in the Elderly Patient Accepted for publication Sept 5 2012Evidence Based Spine Journal

5 Tan Y Montgomery SR Aghdasi BG Inoue H Kaner T Tian H Terrell R Zhang X Wang JC Daubs MD The Effect of Corticosteroid Administration on Soft Tissue Inflammation Associated with rhBMP-2 use in a Rodent Model of Inflammation Spine (Phila Pa 1976) 2012 Nov 28 [Epub ahead of print]

18

Bioengineering and Patricia Zuk PhD in the Department of Plastic Surgery on tissue engineering for ACL reconstruction and rotator cuff repair Drs Sharon Hame and David McAllister continue to participate in clinical research including outcomes of ACL reconstruction Both are co-investigators in the NIH-funded multicenter ACL Revision Surgery (MARS) study Both also continue to collect and analyze data on primary ACL reconstruction Drs Hame McAllister Gamradt and Petrigliano have all recently completed studies on the incidence of shoulder and knee procedures using the Peardiver database

19

Jeffrey Eckardt MD Professor and Chair Orthopaedic Surgery UCLA

Anthony Scaduto MD Executive Vice Chair and President and CAO LAOH

Jeffrey Wang MD Vice Chair of Clinical Operations Orthopaedic Surgery UCLA

John Adams MD Vice Chair of Research Orthopaedic Surgery UCLA

James Luck MD Residency Program Director Orthopaedic Surgery UCLAOH

FACULTY There are presently 73 faculty members in our Department of Orthopaedic Surgery

Foot and Ankle Surgery Andrea Cracchiolo III MD (Emeritus) Nelson SooHoo MD (Division Chief) Lewis Zionts MD

General Orthopaedics Peter Alexakis MD Bruce Brown MD PhD S Andrew Schwartz MD

Hand Surgery Kodi Azari MD Prosper Benhaim MD (Division Chief) Scott Mitchell MD

Joint Replacement Benjamin Bengs MD Bruce Brown MD PhD Francis Cyran MD Gerald Finerman MD Eric Johnson MD James Luck MD Bert Thomas MD (Division Chief)

Musculoskeletal Oncology Susan Bukata MD Francis Cyran MD Jeffrey Eckardt MD (Division Chief)

Osteoporosis John Adams MD Susan Bukata MD Aurelia Nattiv MD

Pediatric OrthopaedicsOrthopaedic Hospital Richard Bowen MD James Luck MD William Oppenheim MD Anthony Scaduto MD (Division Chief) Mauricio Silva MD Lewis Zionts MD

Spine SurgeryPMampR Richard Bowen MD Michael Daubs MD David Fish MD MPH (PMampR) Jae Jung MD (PMampR) Anthony Scaduto MD A Nick Shamie MD Jeffrey Wang MD (Division Chief)

Sports Medicine Richard Bowen MD Gerald Finerman MD Sharon Hame MD David McAllister MD (Division Chief) Robert Pedowitz MD PhD

Frank Petrigliano MD

Sports Medicine amp Non-Operative Orthopaedics John DiFiori MD (Division Chief) Heather Gillespie MD MPH Aurelia Nattiv MD Daniel Vigil MD

Trauma Surgery Benjamin Bengs MD Eric Farrell MD Devon Jeffcoat MD Eric Johnson MD (Division Chief)

Shriners Hospital Katherine Au MD Robert Cho MD Anna Cuomo MD Kathryn Doughty MD Colin Mosely MD Kit Song MD (Service Chief) Hugh Watts MD

VA Hospital Bruce Brown MD PhD Francis Cyran MD Sharon Hame MD Eric Johnson MD David McAllister MD Scott Mitchell MD Frank Petrigliano MD Nelson SooHoo MD (Service Chief) Bert Thomas MD Steven Zeitzew MD

Research Faculty John Adams MD (Vice Chair of Research) Maria-Grazia Ascenzi PhD Paul Bajaj PhD Fabrizio Billi PhD Daniel Boguszewski PhD Patricia Campbell PhD Daniel Cohn PhD Gay Crooks PhD Edward Ebramzadeh PhD Denis Evseenko MD PhD Eileen Fowler PhD PT Martin Hewison PhD Luisa Iruela-Arispe PhD Deborah Krakow MD Susan Krum PhD Timothy Lane PhD Philip Liu PhD Daniel Lu MD PhD Zhen Lu PhD Karen Lyons PhD Keith Markolf PhD Harry McKellop PhD Shen Pang PhD Sang-Hyun Park PhD Bruno Peault PhD Sophia Sangiorgio PhD Fu Wen Shen PhD B Chia Soo MD Kang Ting DMD Howard Winet PhD Benjamin Wu DDS PhD

20

RECENT FACULTY HONORS AND PUBLICATIONS John Adams MD

1 Vitamin D 3rd Edition Feldman DR Pike JW Adams JS eds San Diego Elsevier Press 2011

2 Chen H Gilbert LC Lu X Liu Z You S Weitzmann MN Nanes MS Adams JS Estrogen response element binding protein stimulates osteoclastogenesis and bone resorption J Bone Min Res 262537-2547 2011 PMCID PMC3417837

3 Fabri M Stenger S Shin D Yuk J Liu PT Realegeno S Lee H Krutzik SR Schenk M Sieling PA Teles R Montoya D Iyer SS Bruns H Lewinsohn DM Hollis BW Hewison M Adams JS Steinmeyer A Zuumlgel U Cheng G Jo E Bloom BR Modlin RL Vitamin D is required for IFN-γ mediated antimicrobial activity of human macrophages Sci Transl Med 3104ra102 2011 PMCID PMC3269210

4 Billi F Benya B Kavanaugh A Adams JS Ebramzadeh E McKellop H The John Charnley Award An accurate and extremely sensitive method to separate display and characterize wear debris part 1ndashpolythylene particles Clin Orthopaed Rel Res 470329-338 2012 PMCID PMC 3254734

5 James AW Pang S Askarinam A Corselli M Zara JN Goyal R Chang L Pan A Shen J Yuan W Stoker D Zhang X Adams JS Ting K Soo C Additive effects of sonic hedgehog and Nell-1 signaling in osteogenic versus adipogenic differentiation of human adipose-derived stromal cells Stem Cells Dev 212170-2178 2012 PMCID PMC3411358

Kodi Azari MD 1 Azari K Imbriglia JE Goitz RJ Shores JT Balk ML

Brandacher G Schneeberger S Gorantla V Lee WPldquoHandTransplantion The Donor and Operationrdquo Journal of Reconstructive Microsurgery (2012) 28(1) 27-34

2 Sue McDiarmid and Kodi Azari ldquoDonor Related Issues in Hand Transplantaionrdquo Hand Clinics (2011) 274 545-54

3 Tristan L Hartzell Prosper Benhaim Joeseph E Imbriglia Jaimie Shores Robert J Goitz Marshall Balk Scott Mitchell Roee Rubinstein Vijay Gorantla Stephan Schneeberger Gerald Brandacher W P Andrew LeeKodi K Azari ldquoSurgical and Technical Aspects of Hand Transplantation ndash Is it Just Another Replantrdquo Hand Clinics (2011) 274 521-30

4 Immune Modulation for Hand Transplantation Changing the Risk-Benefit Balance Brandacher G Gorantla VS Schneeberger S Shores JT Imbriglia JE Azari K Donnenberg AD Cooney DS Losee JE Lee WPA J Healthcare Science Humanities 20111(4)62-68

5 Elaine Horibe Song Afshin Shirazian Brian

Binns Yuedi Fleming Lydia M Ferreira Rod J Rohrich Kodi Azari ldquoBenchmarking academic plastic surgery services in the USrdquo Plastic and Reconstructive Surgery (2012) 129(6)1407-18

Benjamin Bengs MD

1 Bengs BC Sangiorgio SN Ebramzadeh E Achieving Clinically Adequate Stem Fixation Despite Severe Proximal Femoral Bone Loss Poster P039 Orthopedic Research Society Annual Meeting San Fransisco CA 2012

2 Sangiorgio S Knutsen A Kalma J Ebramzadeh E Bengs B Can a Dual-tapered Press-fit Stem be used in Cases with Severe Proximal Femoral Defects AAOS Poster 2043 Annual Meeting in San Francisco CA

3 Sugi M Sheridan K Lewis L Huang MH Nattiv A Kado DM BC Bengs Active referral intervention following fragility fractures leads to enhanced osteoporosis follow-up carerdquo Journal of Osteoporosis (accepted 2012)

4 Sangiorgio S Ebramzadeh E Knutsen A Kalma J Bengs B Can a Dual-tapered Press-fit Stem be used in Cases with Severe Proximal Femoral Defects Journal of Biomaterials and Biomechanics (accepted 2012)

5 Aaron W James Jia Shen Xinli Zhang Michael Chiang Asal Askarinam Raghav Goyal Alan Nguyen Janette N Zara Greg Asatrian Jonguk Chung Benjamin Bengs Cymbeline T Culiat A Simon Turner Howard B Seim III John S Adams Kang Ting Chia Soo Nell-1 Regulates Osteoblast Osteoclast Activity and Activates Wntβ-catenin Signaling A New Cause and Treatment for Osteoporosis (submitted for publication)

Prosper Benhaim MD 1 Benhaim P Anthony JP Lin LYT McCalmont TH

Mathes SJ A long-term study of allogeneic rat hindlimb transplants immunosuppressed with RS-61443 Transplantation 1993 56(4) 911-917

2 Tejwani SG Markolf KL Benhaim P Graft reconstruction of the interosseous membrane in conjunction with metallic radial head replacement a cadaveric study Journal of Hand Surgery 2005 30A(2) 335-342

3 Markolf KL Tejwani SG Benhaim P Effects of wafer resection and hemiresection from the distal ulna on load-sharing at the wrist a cadaveric study Journal of Bone and Joint Surgery 2005 30A(2) 351-358

4 Dragoo JL Lieberman JR Lee RS DeUgarte DA Lee Y Zuk PA Hedrick MH Benhaim P ldquoTissue engineered bone from BMP-2 transduced stem cells derived from human fat Plastic and Reconstructive Surgery 2005 115(6) 1665-1673

21

5 Dragoo JL Carlson G McCormick F Khan-Farooqi H Zhu M Zuk PA Benhaim P Healing full-thickness cartilage defects using adipose-derived stem cells Tissue Engineering 2007 13(7) 1615-1621

Nicholas Bernthal MD

1 Kremen TJ Jr Bernthal NM Eckardt MA Eckardt JJ Giant cell tumor of bone are we stratifying results appropriately Clin Orthop Relat Res 2012 Mar470(3)677-83

2 Bernthal NM Federman N Eilber FR Nelson SD Eckardt JJ Eilber FC Tap WD Long-term results (gt25 years) of a randomized prospective clinical trial evaluating chemotherapy in patients with high-grade operable osteosarcoma Cancer 2012 Dec 1118(23)5888-93 doi 101002cncr27651 Epub 2012 May 30

3 Pribaz JR Bernthal NM Wong TC Silva M Lateral spurring (overgrowth) after pediatric lateral condyle fractures J Pediatr Orthop 2012 Jul-Aug32(5)456-60

4 Silva M Knutsen AR Kalma JJ Borkowski SL Bernthal NM Spencer HT Sangiorgio SN Ebramzadeh E Biomechanical Testing of Pin Configurations in Supracondylar Humeral Fractures The Effect of Medial Column Comminution J Orthop Trauma 2012 Aug 28 [Epub ahead of print]

5 Niska JA Meganck JA Pribaz JR Shahbazian JH Lim E Zhang N Rice BW Akin A Ramos RI Bernthal NM Francis KP Miller LS Monitoring bacterial burden inflammation and bone damage longitudinally using optical and μCT imaging in an orthopaedic implant infection in mice PLoS One 20127(10)e47397 doi 101371journalpone0047397 Epub 2012 Oct 17

Rick Bowen MD

1 POSNA Traveling Fellowship Recipient (2008) 2 Bowen RE Scaduto AA Banuelos S Does early

thoracic fusion exacerbate preexisting restrictive lung disease in congenital scoliosis patients J Pediatr Orthop 28 506-511 2008

3 Bowen RE Scaduto AA Banuelos S Decreased body mass index and restrictive lung disease in congenital thoracic scoliosis J Pediatr Orthop 28665-8 2008

4 Bowen RE Gardner S Scaduto AA Eagan M Beckstead J Efficacy of intraoperative cell salvage systems in pediatric idiopathic scoliosis patients undergoing posterior spinal fusion with segmental spinal instrumentationSpine (Phila Pa 1976) 35246-51 2010

5 Bowen RE Knee injuries in the youth athlete Curr Orthop Prac 2012 23 422-428

Susan Bukata MD 1 Houck J Kneiss J Bukata SV Puzas JE Analysis of

vertical ground reaction force variables during a Sit to Stand task in participants recovering from a hip fracture Clin Biomech 2011 Jun 26(5) 470-6

2 Takahata M Awad HA OrsquoKeefe RJ Bukata SV Schwarz EM Endogenous tissue engineering PTH therapy for skeletal repair Cell Tissue Res 2011 May 31 [Epub ahead of print]

3 Kates SL Bukata SV DiGiovanni BF Friedman SL et al A guide to improving the care of patients with fragility fractures Geriatric Orthopaedic Surgery amp Rehabilitation 2011 2(1) 5-37

4 Sampson ER Chen D Schwarz EM Bukata SV OrsquoKeefe RJ Awad H Puzas JE Zuscik MJ Rosier RN Teriparatide as a chondro-regenerative therapy for injury-induced knee osteoarthritis Science Translational Medicine 2011 Sept 21 3(101) 101ra93

5 Kneiss JA Houck JR Bukata SV Puzas JE Influence of Upper Extremity Assistance on Lower Extremity Force Application Symmetry in Individuals Post-Hip Fracture During the Sit-to-Stand Task Journal of Orthopaedic amp Sports Physical Therapy 2012 May 42(5) 474-481

Michael Daubs MD

1 Patton CM Hung M Lawrence BD Patel A Woodbury AM Brodke DS Daubs MD Psychological Distress in a Department of Veteransrsquo Affairs Spine Patient Population The Spine J 2011 Nov 15 (epub ahead of print)

2 Daubs MD Lenke LG Kim YJ Cheh G Stobbs G Bridwell KH Does Correction of Preoperative Coronal Imbalance Make a Difference in Outcomes of Adult Deformity Patients Accepted for publication Spine June 2012

3 Daubs MD Patel AA Lawrence BD Brodke DS Excision of the Posterior Longitudinal Ligament During Anterior Cervical Corpectomy A Biomechanical Study Accepted for publication September 12 2012J Spinal Disorders

4 Daubs MD Lenke LG Cheh G Bridwell KH Kim YJ Stobbs G Decompression Alone Versus Decompression with Limited Fusion for the Treatment of Degenerative Lumbar Scoliosis in the Elderly Patient Accepted for publication Sept 5 2012Evidence Based Spine Journal

5 Tan Y Montgomery SR Aghdasi BG Inoue H Kaner T Tian H Terrell R Zhang X Wang JC Daubs MD The Effect of Corticosteroid Administration on Soft Tissue Inflammation Associated with rhBMP-2 use in a Rodent Model of Inflammation Spine (Phila Pa 1976) 2012 Nov 28 [Epub ahead of print]

19

Jeffrey Eckardt MD Professor and Chair Orthopaedic Surgery UCLA

Anthony Scaduto MD Executive Vice Chair and President and CAO LAOH

Jeffrey Wang MD Vice Chair of Clinical Operations Orthopaedic Surgery UCLA

John Adams MD Vice Chair of Research Orthopaedic Surgery UCLA

James Luck MD Residency Program Director Orthopaedic Surgery UCLAOH

FACULTY There are presently 73 faculty members in our Department of Orthopaedic Surgery

Foot and Ankle Surgery Andrea Cracchiolo III MD (Emeritus) Nelson SooHoo MD (Division Chief) Lewis Zionts MD

General Orthopaedics Peter Alexakis MD Bruce Brown MD PhD S Andrew Schwartz MD

Hand Surgery Kodi Azari MD Prosper Benhaim MD (Division Chief) Scott Mitchell MD

Joint Replacement Benjamin Bengs MD Bruce Brown MD PhD Francis Cyran MD Gerald Finerman MD Eric Johnson MD James Luck MD Bert Thomas MD (Division Chief)

Musculoskeletal Oncology Susan Bukata MD Francis Cyran MD Jeffrey Eckardt MD (Division Chief)

Osteoporosis John Adams MD Susan Bukata MD Aurelia Nattiv MD

Pediatric OrthopaedicsOrthopaedic Hospital Richard Bowen MD James Luck MD William Oppenheim MD Anthony Scaduto MD (Division Chief) Mauricio Silva MD Lewis Zionts MD

Spine SurgeryPMampR Richard Bowen MD Michael Daubs MD David Fish MD MPH (PMampR) Jae Jung MD (PMampR) Anthony Scaduto MD A Nick Shamie MD Jeffrey Wang MD (Division Chief)

Sports Medicine Richard Bowen MD Gerald Finerman MD Sharon Hame MD David McAllister MD (Division Chief) Robert Pedowitz MD PhD

Frank Petrigliano MD

Sports Medicine amp Non-Operative Orthopaedics John DiFiori MD (Division Chief) Heather Gillespie MD MPH Aurelia Nattiv MD Daniel Vigil MD

Trauma Surgery Benjamin Bengs MD Eric Farrell MD Devon Jeffcoat MD Eric Johnson MD (Division Chief)

Shriners Hospital Katherine Au MD Robert Cho MD Anna Cuomo MD Kathryn Doughty MD Colin Mosely MD Kit Song MD (Service Chief) Hugh Watts MD

VA Hospital Bruce Brown MD PhD Francis Cyran MD Sharon Hame MD Eric Johnson MD David McAllister MD Scott Mitchell MD Frank Petrigliano MD Nelson SooHoo MD (Service Chief) Bert Thomas MD Steven Zeitzew MD

Research Faculty John Adams MD (Vice Chair of Research) Maria-Grazia Ascenzi PhD Paul Bajaj PhD Fabrizio Billi PhD Daniel Boguszewski PhD Patricia Campbell PhD Daniel Cohn PhD Gay Crooks PhD Edward Ebramzadeh PhD Denis Evseenko MD PhD Eileen Fowler PhD PT Martin Hewison PhD Luisa Iruela-Arispe PhD Deborah Krakow MD Susan Krum PhD Timothy Lane PhD Philip Liu PhD Daniel Lu MD PhD Zhen Lu PhD Karen Lyons PhD Keith Markolf PhD Harry McKellop PhD Shen Pang PhD Sang-Hyun Park PhD Bruno Peault PhD Sophia Sangiorgio PhD Fu Wen Shen PhD B Chia Soo MD Kang Ting DMD Howard Winet PhD Benjamin Wu DDS PhD

20

RECENT FACULTY HONORS AND PUBLICATIONS John Adams MD

1 Vitamin D 3rd Edition Feldman DR Pike JW Adams JS eds San Diego Elsevier Press 2011

2 Chen H Gilbert LC Lu X Liu Z You S Weitzmann MN Nanes MS Adams JS Estrogen response element binding protein stimulates osteoclastogenesis and bone resorption J Bone Min Res 262537-2547 2011 PMCID PMC3417837

3 Fabri M Stenger S Shin D Yuk J Liu PT Realegeno S Lee H Krutzik SR Schenk M Sieling PA Teles R Montoya D Iyer SS Bruns H Lewinsohn DM Hollis BW Hewison M Adams JS Steinmeyer A Zuumlgel U Cheng G Jo E Bloom BR Modlin RL Vitamin D is required for IFN-γ mediated antimicrobial activity of human macrophages Sci Transl Med 3104ra102 2011 PMCID PMC3269210

4 Billi F Benya B Kavanaugh A Adams JS Ebramzadeh E McKellop H The John Charnley Award An accurate and extremely sensitive method to separate display and characterize wear debris part 1ndashpolythylene particles Clin Orthopaed Rel Res 470329-338 2012 PMCID PMC 3254734

5 James AW Pang S Askarinam A Corselli M Zara JN Goyal R Chang L Pan A Shen J Yuan W Stoker D Zhang X Adams JS Ting K Soo C Additive effects of sonic hedgehog and Nell-1 signaling in osteogenic versus adipogenic differentiation of human adipose-derived stromal cells Stem Cells Dev 212170-2178 2012 PMCID PMC3411358

Kodi Azari MD 1 Azari K Imbriglia JE Goitz RJ Shores JT Balk ML

Brandacher G Schneeberger S Gorantla V Lee WPldquoHandTransplantion The Donor and Operationrdquo Journal of Reconstructive Microsurgery (2012) 28(1) 27-34

2 Sue McDiarmid and Kodi Azari ldquoDonor Related Issues in Hand Transplantaionrdquo Hand Clinics (2011) 274 545-54

3 Tristan L Hartzell Prosper Benhaim Joeseph E Imbriglia Jaimie Shores Robert J Goitz Marshall Balk Scott Mitchell Roee Rubinstein Vijay Gorantla Stephan Schneeberger Gerald Brandacher W P Andrew LeeKodi K Azari ldquoSurgical and Technical Aspects of Hand Transplantation ndash Is it Just Another Replantrdquo Hand Clinics (2011) 274 521-30

4 Immune Modulation for Hand Transplantation Changing the Risk-Benefit Balance Brandacher G Gorantla VS Schneeberger S Shores JT Imbriglia JE Azari K Donnenberg AD Cooney DS Losee JE Lee WPA J Healthcare Science Humanities 20111(4)62-68

5 Elaine Horibe Song Afshin Shirazian Brian

Binns Yuedi Fleming Lydia M Ferreira Rod J Rohrich Kodi Azari ldquoBenchmarking academic plastic surgery services in the USrdquo Plastic and Reconstructive Surgery (2012) 129(6)1407-18

Benjamin Bengs MD

1 Bengs BC Sangiorgio SN Ebramzadeh E Achieving Clinically Adequate Stem Fixation Despite Severe Proximal Femoral Bone Loss Poster P039 Orthopedic Research Society Annual Meeting San Fransisco CA 2012

2 Sangiorgio S Knutsen A Kalma J Ebramzadeh E Bengs B Can a Dual-tapered Press-fit Stem be used in Cases with Severe Proximal Femoral Defects AAOS Poster 2043 Annual Meeting in San Francisco CA

3 Sugi M Sheridan K Lewis L Huang MH Nattiv A Kado DM BC Bengs Active referral intervention following fragility fractures leads to enhanced osteoporosis follow-up carerdquo Journal of Osteoporosis (accepted 2012)

4 Sangiorgio S Ebramzadeh E Knutsen A Kalma J Bengs B Can a Dual-tapered Press-fit Stem be used in Cases with Severe Proximal Femoral Defects Journal of Biomaterials and Biomechanics (accepted 2012)

5 Aaron W James Jia Shen Xinli Zhang Michael Chiang Asal Askarinam Raghav Goyal Alan Nguyen Janette N Zara Greg Asatrian Jonguk Chung Benjamin Bengs Cymbeline T Culiat A Simon Turner Howard B Seim III John S Adams Kang Ting Chia Soo Nell-1 Regulates Osteoblast Osteoclast Activity and Activates Wntβ-catenin Signaling A New Cause and Treatment for Osteoporosis (submitted for publication)

Prosper Benhaim MD 1 Benhaim P Anthony JP Lin LYT McCalmont TH

Mathes SJ A long-term study of allogeneic rat hindlimb transplants immunosuppressed with RS-61443 Transplantation 1993 56(4) 911-917

2 Tejwani SG Markolf KL Benhaim P Graft reconstruction of the interosseous membrane in conjunction with metallic radial head replacement a cadaveric study Journal of Hand Surgery 2005 30A(2) 335-342

3 Markolf KL Tejwani SG Benhaim P Effects of wafer resection and hemiresection from the distal ulna on load-sharing at the wrist a cadaveric study Journal of Bone and Joint Surgery 2005 30A(2) 351-358

4 Dragoo JL Lieberman JR Lee RS DeUgarte DA Lee Y Zuk PA Hedrick MH Benhaim P ldquoTissue engineered bone from BMP-2 transduced stem cells derived from human fat Plastic and Reconstructive Surgery 2005 115(6) 1665-1673

21

5 Dragoo JL Carlson G McCormick F Khan-Farooqi H Zhu M Zuk PA Benhaim P Healing full-thickness cartilage defects using adipose-derived stem cells Tissue Engineering 2007 13(7) 1615-1621

Nicholas Bernthal MD

1 Kremen TJ Jr Bernthal NM Eckardt MA Eckardt JJ Giant cell tumor of bone are we stratifying results appropriately Clin Orthop Relat Res 2012 Mar470(3)677-83

2 Bernthal NM Federman N Eilber FR Nelson SD Eckardt JJ Eilber FC Tap WD Long-term results (gt25 years) of a randomized prospective clinical trial evaluating chemotherapy in patients with high-grade operable osteosarcoma Cancer 2012 Dec 1118(23)5888-93 doi 101002cncr27651 Epub 2012 May 30

3 Pribaz JR Bernthal NM Wong TC Silva M Lateral spurring (overgrowth) after pediatric lateral condyle fractures J Pediatr Orthop 2012 Jul-Aug32(5)456-60

4 Silva M Knutsen AR Kalma JJ Borkowski SL Bernthal NM Spencer HT Sangiorgio SN Ebramzadeh E Biomechanical Testing of Pin Configurations in Supracondylar Humeral Fractures The Effect of Medial Column Comminution J Orthop Trauma 2012 Aug 28 [Epub ahead of print]

5 Niska JA Meganck JA Pribaz JR Shahbazian JH Lim E Zhang N Rice BW Akin A Ramos RI Bernthal NM Francis KP Miller LS Monitoring bacterial burden inflammation and bone damage longitudinally using optical and μCT imaging in an orthopaedic implant infection in mice PLoS One 20127(10)e47397 doi 101371journalpone0047397 Epub 2012 Oct 17

Rick Bowen MD

1 POSNA Traveling Fellowship Recipient (2008) 2 Bowen RE Scaduto AA Banuelos S Does early

thoracic fusion exacerbate preexisting restrictive lung disease in congenital scoliosis patients J Pediatr Orthop 28 506-511 2008

3 Bowen RE Scaduto AA Banuelos S Decreased body mass index and restrictive lung disease in congenital thoracic scoliosis J Pediatr Orthop 28665-8 2008

4 Bowen RE Gardner S Scaduto AA Eagan M Beckstead J Efficacy of intraoperative cell salvage systems in pediatric idiopathic scoliosis patients undergoing posterior spinal fusion with segmental spinal instrumentationSpine (Phila Pa 1976) 35246-51 2010

5 Bowen RE Knee injuries in the youth athlete Curr Orthop Prac 2012 23 422-428

Susan Bukata MD 1 Houck J Kneiss J Bukata SV Puzas JE Analysis of

vertical ground reaction force variables during a Sit to Stand task in participants recovering from a hip fracture Clin Biomech 2011 Jun 26(5) 470-6

2 Takahata M Awad HA OrsquoKeefe RJ Bukata SV Schwarz EM Endogenous tissue engineering PTH therapy for skeletal repair Cell Tissue Res 2011 May 31 [Epub ahead of print]

3 Kates SL Bukata SV DiGiovanni BF Friedman SL et al A guide to improving the care of patients with fragility fractures Geriatric Orthopaedic Surgery amp Rehabilitation 2011 2(1) 5-37

4 Sampson ER Chen D Schwarz EM Bukata SV OrsquoKeefe RJ Awad H Puzas JE Zuscik MJ Rosier RN Teriparatide as a chondro-regenerative therapy for injury-induced knee osteoarthritis Science Translational Medicine 2011 Sept 21 3(101) 101ra93

5 Kneiss JA Houck JR Bukata SV Puzas JE Influence of Upper Extremity Assistance on Lower Extremity Force Application Symmetry in Individuals Post-Hip Fracture During the Sit-to-Stand Task Journal of Orthopaedic amp Sports Physical Therapy 2012 May 42(5) 474-481

Michael Daubs MD

1 Patton CM Hung M Lawrence BD Patel A Woodbury AM Brodke DS Daubs MD Psychological Distress in a Department of Veteransrsquo Affairs Spine Patient Population The Spine J 2011 Nov 15 (epub ahead of print)

2 Daubs MD Lenke LG Kim YJ Cheh G Stobbs G Bridwell KH Does Correction of Preoperative Coronal Imbalance Make a Difference in Outcomes of Adult Deformity Patients Accepted for publication Spine June 2012

3 Daubs MD Patel AA Lawrence BD Brodke DS Excision of the Posterior Longitudinal Ligament During Anterior Cervical Corpectomy A Biomechanical Study Accepted for publication September 12 2012J Spinal Disorders

4 Daubs MD Lenke LG Cheh G Bridwell KH Kim YJ Stobbs G Decompression Alone Versus Decompression with Limited Fusion for the Treatment of Degenerative Lumbar Scoliosis in the Elderly Patient Accepted for publication Sept 5 2012Evidence Based Spine Journal

5 Tan Y Montgomery SR Aghdasi BG Inoue H Kaner T Tian H Terrell R Zhang X Wang JC Daubs MD The Effect of Corticosteroid Administration on Soft Tissue Inflammation Associated with rhBMP-2 use in a Rodent Model of Inflammation Spine (Phila Pa 1976) 2012 Nov 28 [Epub ahead of print]

20

RECENT FACULTY HONORS AND PUBLICATIONS John Adams MD

1 Vitamin D 3rd Edition Feldman DR Pike JW Adams JS eds San Diego Elsevier Press 2011

2 Chen H Gilbert LC Lu X Liu Z You S Weitzmann MN Nanes MS Adams JS Estrogen response element binding protein stimulates osteoclastogenesis and bone resorption J Bone Min Res 262537-2547 2011 PMCID PMC3417837

3 Fabri M Stenger S Shin D Yuk J Liu PT Realegeno S Lee H Krutzik SR Schenk M Sieling PA Teles R Montoya D Iyer SS Bruns H Lewinsohn DM Hollis BW Hewison M Adams JS Steinmeyer A Zuumlgel U Cheng G Jo E Bloom BR Modlin RL Vitamin D is required for IFN-γ mediated antimicrobial activity of human macrophages Sci Transl Med 3104ra102 2011 PMCID PMC3269210

4 Billi F Benya B Kavanaugh A Adams JS Ebramzadeh E McKellop H The John Charnley Award An accurate and extremely sensitive method to separate display and characterize wear debris part 1ndashpolythylene particles Clin Orthopaed Rel Res 470329-338 2012 PMCID PMC 3254734

5 James AW Pang S Askarinam A Corselli M Zara JN Goyal R Chang L Pan A Shen J Yuan W Stoker D Zhang X Adams JS Ting K Soo C Additive effects of sonic hedgehog and Nell-1 signaling in osteogenic versus adipogenic differentiation of human adipose-derived stromal cells Stem Cells Dev 212170-2178 2012 PMCID PMC3411358

Kodi Azari MD 1 Azari K Imbriglia JE Goitz RJ Shores JT Balk ML

Brandacher G Schneeberger S Gorantla V Lee WPldquoHandTransplantion The Donor and Operationrdquo Journal of Reconstructive Microsurgery (2012) 28(1) 27-34

2 Sue McDiarmid and Kodi Azari ldquoDonor Related Issues in Hand Transplantaionrdquo Hand Clinics (2011) 274 545-54

3 Tristan L Hartzell Prosper Benhaim Joeseph E Imbriglia Jaimie Shores Robert J Goitz Marshall Balk Scott Mitchell Roee Rubinstein Vijay Gorantla Stephan Schneeberger Gerald Brandacher W P Andrew LeeKodi K Azari ldquoSurgical and Technical Aspects of Hand Transplantation ndash Is it Just Another Replantrdquo Hand Clinics (2011) 274 521-30

4 Immune Modulation for Hand Transplantation Changing the Risk-Benefit Balance Brandacher G Gorantla VS Schneeberger S Shores JT Imbriglia JE Azari K Donnenberg AD Cooney DS Losee JE Lee WPA J Healthcare Science Humanities 20111(4)62-68

5 Elaine Horibe Song Afshin Shirazian Brian

Binns Yuedi Fleming Lydia M Ferreira Rod J Rohrich Kodi Azari ldquoBenchmarking academic plastic surgery services in the USrdquo Plastic and Reconstructive Surgery (2012) 129(6)1407-18

Benjamin Bengs MD

1 Bengs BC Sangiorgio SN Ebramzadeh E Achieving Clinically Adequate Stem Fixation Despite Severe Proximal Femoral Bone Loss Poster P039 Orthopedic Research Society Annual Meeting San Fransisco CA 2012

2 Sangiorgio S Knutsen A Kalma J Ebramzadeh E Bengs B Can a Dual-tapered Press-fit Stem be used in Cases with Severe Proximal Femoral Defects AAOS Poster 2043 Annual Meeting in San Francisco CA

3 Sugi M Sheridan K Lewis L Huang MH Nattiv A Kado DM BC Bengs Active referral intervention following fragility fractures leads to enhanced osteoporosis follow-up carerdquo Journal of Osteoporosis (accepted 2012)

4 Sangiorgio S Ebramzadeh E Knutsen A Kalma J Bengs B Can a Dual-tapered Press-fit Stem be used in Cases with Severe Proximal Femoral Defects Journal of Biomaterials and Biomechanics (accepted 2012)

5 Aaron W James Jia Shen Xinli Zhang Michael Chiang Asal Askarinam Raghav Goyal Alan Nguyen Janette N Zara Greg Asatrian Jonguk Chung Benjamin Bengs Cymbeline T Culiat A Simon Turner Howard B Seim III John S Adams Kang Ting Chia Soo Nell-1 Regulates Osteoblast Osteoclast Activity and Activates Wntβ-catenin Signaling A New Cause and Treatment for Osteoporosis (submitted for publication)

Prosper Benhaim MD 1 Benhaim P Anthony JP Lin LYT McCalmont TH

Mathes SJ A long-term study of allogeneic rat hindlimb transplants immunosuppressed with RS-61443 Transplantation 1993 56(4) 911-917

2 Tejwani SG Markolf KL Benhaim P Graft reconstruction of the interosseous membrane in conjunction with metallic radial head replacement a cadaveric study Journal of Hand Surgery 2005 30A(2) 335-342

3 Markolf KL Tejwani SG Benhaim P Effects of wafer resection and hemiresection from the distal ulna on load-sharing at the wrist a cadaveric study Journal of Bone and Joint Surgery 2005 30A(2) 351-358

4 Dragoo JL Lieberman JR Lee RS DeUgarte DA Lee Y Zuk PA Hedrick MH Benhaim P ldquoTissue engineered bone from BMP-2 transduced stem cells derived from human fat Plastic and Reconstructive Surgery 2005 115(6) 1665-1673

21

5 Dragoo JL Carlson G McCormick F Khan-Farooqi H Zhu M Zuk PA Benhaim P Healing full-thickness cartilage defects using adipose-derived stem cells Tissue Engineering 2007 13(7) 1615-1621

Nicholas Bernthal MD

1 Kremen TJ Jr Bernthal NM Eckardt MA Eckardt JJ Giant cell tumor of bone are we stratifying results appropriately Clin Orthop Relat Res 2012 Mar470(3)677-83

2 Bernthal NM Federman N Eilber FR Nelson SD Eckardt JJ Eilber FC Tap WD Long-term results (gt25 years) of a randomized prospective clinical trial evaluating chemotherapy in patients with high-grade operable osteosarcoma Cancer 2012 Dec 1118(23)5888-93 doi 101002cncr27651 Epub 2012 May 30

3 Pribaz JR Bernthal NM Wong TC Silva M Lateral spurring (overgrowth) after pediatric lateral condyle fractures J Pediatr Orthop 2012 Jul-Aug32(5)456-60

4 Silva M Knutsen AR Kalma JJ Borkowski SL Bernthal NM Spencer HT Sangiorgio SN Ebramzadeh E Biomechanical Testing of Pin Configurations in Supracondylar Humeral Fractures The Effect of Medial Column Comminution J Orthop Trauma 2012 Aug 28 [Epub ahead of print]

5 Niska JA Meganck JA Pribaz JR Shahbazian JH Lim E Zhang N Rice BW Akin A Ramos RI Bernthal NM Francis KP Miller LS Monitoring bacterial burden inflammation and bone damage longitudinally using optical and μCT imaging in an orthopaedic implant infection in mice PLoS One 20127(10)e47397 doi 101371journalpone0047397 Epub 2012 Oct 17

Rick Bowen MD

1 POSNA Traveling Fellowship Recipient (2008) 2 Bowen RE Scaduto AA Banuelos S Does early

thoracic fusion exacerbate preexisting restrictive lung disease in congenital scoliosis patients J Pediatr Orthop 28 506-511 2008

3 Bowen RE Scaduto AA Banuelos S Decreased body mass index and restrictive lung disease in congenital thoracic scoliosis J Pediatr Orthop 28665-8 2008

4 Bowen RE Gardner S Scaduto AA Eagan M Beckstead J Efficacy of intraoperative cell salvage systems in pediatric idiopathic scoliosis patients undergoing posterior spinal fusion with segmental spinal instrumentationSpine (Phila Pa 1976) 35246-51 2010

5 Bowen RE Knee injuries in the youth athlete Curr Orthop Prac 2012 23 422-428

Susan Bukata MD 1 Houck J Kneiss J Bukata SV Puzas JE Analysis of

vertical ground reaction force variables during a Sit to Stand task in participants recovering from a hip fracture Clin Biomech 2011 Jun 26(5) 470-6

2 Takahata M Awad HA OrsquoKeefe RJ Bukata SV Schwarz EM Endogenous tissue engineering PTH therapy for skeletal repair Cell Tissue Res 2011 May 31 [Epub ahead of print]

3 Kates SL Bukata SV DiGiovanni BF Friedman SL et al A guide to improving the care of patients with fragility fractures Geriatric Orthopaedic Surgery amp Rehabilitation 2011 2(1) 5-37

4 Sampson ER Chen D Schwarz EM Bukata SV OrsquoKeefe RJ Awad H Puzas JE Zuscik MJ Rosier RN Teriparatide as a chondro-regenerative therapy for injury-induced knee osteoarthritis Science Translational Medicine 2011 Sept 21 3(101) 101ra93

5 Kneiss JA Houck JR Bukata SV Puzas JE Influence of Upper Extremity Assistance on Lower Extremity Force Application Symmetry in Individuals Post-Hip Fracture During the Sit-to-Stand Task Journal of Orthopaedic amp Sports Physical Therapy 2012 May 42(5) 474-481

Michael Daubs MD

1 Patton CM Hung M Lawrence BD Patel A Woodbury AM Brodke DS Daubs MD Psychological Distress in a Department of Veteransrsquo Affairs Spine Patient Population The Spine J 2011 Nov 15 (epub ahead of print)

2 Daubs MD Lenke LG Kim YJ Cheh G Stobbs G Bridwell KH Does Correction of Preoperative Coronal Imbalance Make a Difference in Outcomes of Adult Deformity Patients Accepted for publication Spine June 2012

3 Daubs MD Patel AA Lawrence BD Brodke DS Excision of the Posterior Longitudinal Ligament During Anterior Cervical Corpectomy A Biomechanical Study Accepted for publication September 12 2012J Spinal Disorders

4 Daubs MD Lenke LG Cheh G Bridwell KH Kim YJ Stobbs G Decompression Alone Versus Decompression with Limited Fusion for the Treatment of Degenerative Lumbar Scoliosis in the Elderly Patient Accepted for publication Sept 5 2012Evidence Based Spine Journal

5 Tan Y Montgomery SR Aghdasi BG Inoue H Kaner T Tian H Terrell R Zhang X Wang JC Daubs MD The Effect of Corticosteroid Administration on Soft Tissue Inflammation Associated with rhBMP-2 use in a Rodent Model of Inflammation Spine (Phila Pa 1976) 2012 Nov 28 [Epub ahead of print]

21

5 Dragoo JL Carlson G McCormick F Khan-Farooqi H Zhu M Zuk PA Benhaim P Healing full-thickness cartilage defects using adipose-derived stem cells Tissue Engineering 2007 13(7) 1615-1621

Nicholas Bernthal MD

1 Kremen TJ Jr Bernthal NM Eckardt MA Eckardt JJ Giant cell tumor of bone are we stratifying results appropriately Clin Orthop Relat Res 2012 Mar470(3)677-83

2 Bernthal NM Federman N Eilber FR Nelson SD Eckardt JJ Eilber FC Tap WD Long-term results (gt25 years) of a randomized prospective clinical trial evaluating chemotherapy in patients with high-grade operable osteosarcoma Cancer 2012 Dec 1118(23)5888-93 doi 101002cncr27651 Epub 2012 May 30

3 Pribaz JR Bernthal NM Wong TC Silva M Lateral spurring (overgrowth) after pediatric lateral condyle fractures J Pediatr Orthop 2012 Jul-Aug32(5)456-60

4 Silva M Knutsen AR Kalma JJ Borkowski SL Bernthal NM Spencer HT Sangiorgio SN Ebramzadeh E Biomechanical Testing of Pin Configurations in Supracondylar Humeral Fractures The Effect of Medial Column Comminution J Orthop Trauma 2012 Aug 28 [Epub ahead of print]

5 Niska JA Meganck JA Pribaz JR Shahbazian JH Lim E Zhang N Rice BW Akin A Ramos RI Bernthal NM Francis KP Miller LS Monitoring bacterial burden inflammation and bone damage longitudinally using optical and μCT imaging in an orthopaedic implant infection in mice PLoS One 20127(10)e47397 doi 101371journalpone0047397 Epub 2012 Oct 17

Rick Bowen MD

1 POSNA Traveling Fellowship Recipient (2008) 2 Bowen RE Scaduto AA Banuelos S Does early

thoracic fusion exacerbate preexisting restrictive lung disease in congenital scoliosis patients J Pediatr Orthop 28 506-511 2008

3 Bowen RE Scaduto AA Banuelos S Decreased body mass index and restrictive lung disease in congenital thoracic scoliosis J Pediatr Orthop 28665-8 2008

4 Bowen RE Gardner S Scaduto AA Eagan M Beckstead J Efficacy of intraoperative cell salvage systems in pediatric idiopathic scoliosis patients undergoing posterior spinal fusion with segmental spinal instrumentationSpine (Phila Pa 1976) 35246-51 2010

5 Bowen RE Knee injuries in the youth athlete Curr Orthop Prac 2012 23 422-428

Susan Bukata MD 1 Houck J Kneiss J Bukata SV Puzas JE Analysis of

vertical ground reaction force variables during a Sit to Stand task in participants recovering from a hip fracture Clin Biomech 2011 Jun 26(5) 470-6

2 Takahata M Awad HA OrsquoKeefe RJ Bukata SV Schwarz EM Endogenous tissue engineering PTH therapy for skeletal repair Cell Tissue Res 2011 May 31 [Epub ahead of print]

3 Kates SL Bukata SV DiGiovanni BF Friedman SL et al A guide to improving the care of patients with fragility fractures Geriatric Orthopaedic Surgery amp Rehabilitation 2011 2(1) 5-37

4 Sampson ER Chen D Schwarz EM Bukata SV OrsquoKeefe RJ Awad H Puzas JE Zuscik MJ Rosier RN Teriparatide as a chondro-regenerative therapy for injury-induced knee osteoarthritis Science Translational Medicine 2011 Sept 21 3(101) 101ra93

5 Kneiss JA Houck JR Bukata SV Puzas JE Influence of Upper Extremity Assistance on Lower Extremity Force Application Symmetry in Individuals Post-Hip Fracture During the Sit-to-Stand Task Journal of Orthopaedic amp Sports Physical Therapy 2012 May 42(5) 474-481

Michael Daubs MD

1 Patton CM Hung M Lawrence BD Patel A Woodbury AM Brodke DS Daubs MD Psychological Distress in a Department of Veteransrsquo Affairs Spine Patient Population The Spine J 2011 Nov 15 (epub ahead of print)

2 Daubs MD Lenke LG Kim YJ Cheh G Stobbs G Bridwell KH Does Correction of Preoperative Coronal Imbalance Make a Difference in Outcomes of Adult Deformity Patients Accepted for publication Spine June 2012

3 Daubs MD Patel AA Lawrence BD Brodke DS Excision of the Posterior Longitudinal Ligament During Anterior Cervical Corpectomy A Biomechanical Study Accepted for publication September 12 2012J Spinal Disorders

4 Daubs MD Lenke LG Cheh G Bridwell KH Kim YJ Stobbs G Decompression Alone Versus Decompression with Limited Fusion for the Treatment of Degenerative Lumbar Scoliosis in the Elderly Patient Accepted for publication Sept 5 2012Evidence Based Spine Journal

5 Tan Y Montgomery SR Aghdasi BG Inoue H Kaner T Tian H Terrell R Zhang X Wang JC Daubs MD The Effect of Corticosteroid Administration on Soft Tissue Inflammation Associated with rhBMP-2 use in a Rodent Model of Inflammation Spine (Phila Pa 1976) 2012 Nov 28 [Epub ahead of print]

22

John DiFiori MD 1 Babikian T DiFiori J Giza C ldquoPathophysiologic

Outcomes of Mild Traumatic Brain Injuryrdquoin Pediatric Mild Traumatic Brain Injury From Basic Science to Clinical Management Kirkwood M Yeates K editors Guilford Press 2012

2 Giza C and DiFiori JP Pathophysiology of Sports-Related Concussion Basic Science and Translational Research Sports Health 3(1)46-51 2011

3 DiFiori JP Overuse Injury of the Physis A Growing Problem Clinical Journal of Sport Medicine 20(5)336-337 September 2010

4 Choe MC Babikian T DiFiori J Hovda DA Giza CC A pediatric perspective on concussion pathophysiology Curr Opin Pediatr 2012 Dec24(6)689-95

5 Drezner JA Ackerman MJ Anderson J Ashley E Asplund CA Baggish AL Boumlrjesson M Cannon BC Corrado D Difiori JP Fischbach P Froelicher V Harmon KG Heidbuchel H Marek J Owens DS Paul S Pelliccia A Prutkin JM Salerno JC Schmied CM Sharma S Stein R Vetter VL Wilson MG Electrocardiographic interpretation in athletes the Seattle Criteria Br J Sports Med 2013 Feb47(3)122-4

Jeffrey Eckardt MD

1 Kremen TJ Jr Bernthal NM Eckardt MA Eckardt JJ Giant Cell Tumor of Bone Are We Stratifying Results Appropriately Clin Orthop Rel Res 2012 Mar470(3) 677-83

2 Herrmann K Benz MR Czernin J Allen-Auerbach MS Tap WD Dry SM Schuster T Eckardt JJ Phelps ME Weber WA and Eilber FC 18F-FDG PETCT Imaging as an Early Survival Predictor in Patients with Primary High Grade Soft Tissue Sarcomas undergoing Neoadjuvant Therapy Clin Cancer Res 2012 Apr18(7) 2024-31

3 UyBico SJ Motamedi K Omura MC Nelson SD Eilber FC Eckardt J and Seeger LL Relevance of Compartmental Anatomic Guidelines for Biopsy of Musculoskeletal Tumors Retrospective Review of 363 Biopsies over a 6-Year Period J Vasc Interv Radiol 2012 Apr23(4) 511-18 e1-2

4 Bernthal NM Federman N Eilber FR Nelson SD Eckardt JJ Eilber FC Tap WD Long-Term Results (gt25 years) of a Randomized Prospective Clinical Trial Evaluating Chemotherapy in Patients with High-Grade Operable Osteosarcoma Cancer 2012 Dec118(23) 5888-93

5 Mitton B Seeger LL Eckardt MA Motamedi K Eilber FC Nelson SD Eckardt JJ Federman N Image-Guided Percutaneous Core Needle Biopsies of Musculoskeletal Lesions in Children Journal of Pediatric HematologyOncology Accepted 2012

Eric Farrell MD 1 1 Farrell ED Lafferty P Tibial Plateau Fracturemdash

Infection failure of fixation and instability Prevention of Complications in Fracture Surgery Ed by M Archdeacon SLACK Incorp Thorofare NJ 2012

2 Nydick JA Farrell ED Marcantonio AJ Hume EL Marburger R Ostrum RF The Use of Clopidogrel (Plavix) in Patients Undergoing Nonelective Orthopaedic Surgery J Orthop Trauma 2010 Jun 24(6)383-6

3 Farrell ED Gardner MJ Krieg JC Chip Routt ML Jr The Upper Sacral Nerve Root Tunnel an Anatomic and Clinical Study J Orthop Trauma 2009 May-Jun 23(5) 333-9

4 Gardner MJ Farrell ED Nork SE Segina DN Routt ML Jr Percutaneous Placement of Iliosacral Screws without Electrodiagnostic Monitoring J Trauma 2009 May 66(5) 1411-5

5 Cannada LK Jones TR Guerrero-Bejarano M Viehe T Levy M Farrell ED Ostrum RF Retrograde Intramedullary Nailing of Femoral Diaphyseal Fractures Caused by Low-Velocity Gunshots Orthopedics 2009 Mar 32(3) 162

David Fish MD

1 Evaluating Correlation of Two Pain Scales in Spinal Procedures Fish DE Lee PC Parti A Pham Q Fed Pract 201027(5)24-28

2 The Risk of Radiation Exposure to the Eyes of the Interventional Pain Physician Fish DE Kim A et al Radiology Research and Practice Volume 2011 March 2011

3 Pain Medicine Pocketpedia Kim HS Fish DE Choi H Lippincott Publishing ISBN-10 0781772184 May 2011

4 Evaluation of the Patient with Neck Versus Shoulder Pain Fish DE Gerstman BA Lin V Phys Med Rehabil Clin N Am 22 (2011) 395ndash410

5 Thoracic Outlet Syndrome Ozoa G Alves D Fish DE Phys Med Rehabil Clin N Am 2011 Aug22 (3)473-83

Seth Gamradt MD

1 Accepted American Shoulder and Elbow Surgeons (ASES) October 2012 American Orthopaedic Society for Sports Medicine (AOSSM) Traveling Fellowship South America 2011

2 Gamradt SC Gelber J Zhang AL Shoulder function and pain level after revision of failed reverse shoulder replacement to hemiarthroplasty Int J Shoulder Surg 2012 Apr6(2)29-35

3 Montgomery SR Petrigliano FA Gamradt SC Failed rotator cuff surgery evaluation and decision making Clin Sports Med 2012 Oct31(4)693-712

23

4 Zhang AL Kreulen C Ngo SS Hame SL Wang JC Gamradt SC Demographic trends in arthroscopic SLAP repair in the United States Am J Sports Med 2012 May40(5)1144-7

5 Montgomery SR Petrigliano FA Gamradt SC Biologic augmentation of rotator cuff repair Curr Rev Musculoskelet Med 2011 Dec4(4)221-30

Heather Gillespie MD 1 Gillespie H ldquoNonsteroidal Anti-Inflammatory Drugs

General Risks of Prophylactic Acute and Long-Term Userdquo ACSMrsquos Health and Fitness Journal 2011 Vol 15 (6) 46-47

2 Gillespie HM ldquoOsteochondroses and Apophyseal Injuries of the Foot in the Young Athleterdquo Current Sports Medicine Reports 2010 Sep-Oct9(5)265-8

3 Rich Sisson MD Heather Gillespie MD MPH John DiFiori MD Youth Sports Injuries Presenting to an Urban Underserved Primary Care Sports Medicine Clinic Poster Presentation AMSSM May 2011

4 Gillespie HM Dexter WW ldquoTreatment Options for Osteoarthritis of the Hiprdquo in Seidenberg PH Bowen JD The Hip and Pelvis in Sports Medicine and Primary Care 2010 297-315

Sharon Hame MD

1 Brophy RH Wright RW David TS McCormack RG Sekiya JK Svoboda SJ Huston LJ Haas AK Steger-May K for the Multicenter ACL Revision Study (MARS) Group (Hame S L) Association between previous meniscal surgery and the incidence of chondral lesions at revision anterior cruciate ligament reconstruction Am J Sports Med 2012 Apr 40(4)808-814 Epub 2012 Feb 28

2 Zhang A Ngo S Kreulen C Hame S L Wang J Gamradt S Demographic Trends in Arthroscopic SLAP Repair in the United States Am J Sports Med 2012 May 40(5) Epub 2012 Feb 9

3 Hame SL Nguyen V Ellerman J Ngo S Wang J Gamradt S Complications of arthroscopic meniscectomy in the older population Am J Sports Med 2012 June 40(6) 1402-5 Epub 2012 April 10

4 Montgomery SR Ngo SS Hobson T Nguyen S Alluri R Wang JC Hame SL Trends and Demographics in Hip Arthroscopy in the United States Arthroscopy 2013 Jan 31 [Epub ahead of print]

5 Zhang AL Montgomery SR Ngo SS Hame SL Wang JC Gamradt SC Analysis of rotator cuff repair trends in a large private insurance population Arthroscopy 2013 Jan 31 [Epub ahead of print]

Devon Jeffcoat MD

1 Devon Jeffcoat Eben A Carroll Florian G Huber Anna N Miller Dean G Lorich David L Helfet

Operative Treatment of Acetabular Fractures in an Older Population Through a limited Ilioinguinal Approach J Orthop Trauma 2012 May26(5)284-9

2 Chan D Jeffcoat D Lorich D Helfet D Nonunions around the Knee Int Orthop 2010 Feb34(2)271-81

3 Neil R MacIntyre MD Devon M Jeffcoat MD Daniel B Chan MD Dean G Lorich MD and David L Helfet The Experiences of a Surgical Response Team in Haiti Am J Orthop 201039(4)172-174

4 Neil R MacIntyre MD Devon M Jeffcoat MD Daniel B Chan MD Dean G Lorich MD and David L Helfet The 2010 Haiti Earthquake Lessons Learned Techniques in Hand and Upper Extremity Surgery 201014(2)64

5 Fermor B Jeffcoat D Hennerbichler A Pisetsky DS Weinberg JB Guilak F The effects of cyclic mechanical strain and tumor necrosis factor alpha on the response of cells of the meniscus Osteoarthritis Cartilage 2004 Dec12(12)956-62

David McAllister MD

1 Markolf KL Jackson SR McAllister DR Force Measurements in the Medial Meniscus Posterior Horn Attachment Effects of ACL Removal Am J Sports Med 2012 Feb40(2)332-8 Epub 2011 Nov 15 PMID 22085731

2 Chung AS Hwang HS Das D Zuk P McAllister DR Wu B Lamellar Stack Formation and Degradative Behaviors of Hydrolytically Degraded Poly(ε- aprolactone) and Poly(glycolide-ε-caprolactone) Blended Fibers J Biomed Mater Res B Appl Biomater 2012 Jan100(1)274-84 doi 101002jbmb31950 Epub 2011 Nov 9 PMID 22069303

3 Markolf KL Jackson SR McAllister DR Relationship Between Pivot Shift and Lachman Tests in the ACL Reconstructed Knee A Cadaveric Study J Bone Joint Surg Am 2010 Sep 192(11)2067-75PMID 20810856

4 Markolf KL Jackson SR McAllister DR A Comparison of 11 Oclock vs Oblique Femoral Tunnels in the ACL Reconstructed Knee Knee Kinematics During a Simulated Pivot Test Am J Sports Med 2010 May38(5)912-7PMID 20308433

5 Keith L Markolf Samuel Park Steven R Jackson and David R McAllister Simulated Pivot Shift Testing With Single and Double Bundle ACL Reconstructions J Bone Joint Surg Am 2008 Aug90(8)1681-9PMID 18676898

Scott Mitchell MD

1 Ricci WM Bolhofner BR Loftus T Cox C Mitchell S and Borrelli J Jr Surgical Technique Indirect reduction and plate fixation without grafting for

24

periprosthetic femoral shaft fractures about a stable intramedullary implant Journal of Bone and Joint Surgery Am 200688(Supp 1)275-282

2 Gabbay JS Heller JB Mitchell SA Zuk PA Spoon DB Wasson KL Jarrahy R Benhaim P Bradley JP Osteogenic potentiation of human adipose-derived stem cells in a 3-dimensional matrix Annals of Plastic Surgery 2006 Jul 57(1)89-93

3 Heller JB Gabbay JS Wasson K Mitchell S Heller MM Zuk P Bradley JP Cranial suture response to stress Expression patterns of Noggin and Runx2 Plastic and Reconstructive Surgery 2007 Jun119(7)2037-45

4 Gabbay JS Mitchell SA Alban RF Heller JB Chopra R Feldmar D Nisim AA Kulber D Use of a novel active implant forearm device in treating lateral tendinosis Orthopedics 2007 Dec30(12)1005-9

5 Hartzell TL Benhaim P Imbriglia J Shores J Goitz R Balk M Mitchell S Rubinstein R Gorantla V Schneeberger S Brandacher G Lee WP Azari KK Surgical and Technical Aspects of Hand Transplantation Is it Just Another Replant Hand Clinics 2011 Nov 27(4)521-530

Aurelia Nattiv MD 1 Sugi MT Sheridan K Lewis L Nattiv A Kado DM

Bengs B Active referral intervention following fragility fractures leads to enhanced osteoporosis follow-up care Journal of Osteoporosis vol 2012 2012

2 Arends J Cheung M Barrack M Nattiv A Restoration of menses with nonpharmacologic therapy in collegiate athletes with menstrual disturbances A 5 year retrospective study Int J Sport Nutr Exerc Metab Apr 22(2)98-108 2012

3 Ascenzi M-G Hetzer N Lomovtsev A Rude R Nattiv A Favia A Variation of trabecular architecture in proximal femur of postmenopausal women Journal of Biomechanics 44 (2)248-26 2011

4 Nattiv A [Chair] Loucks A Manore M Sundgot-Borgen J Warren M The American College of Sports Medicine Position Stand on the Female Athlete Triad Med Sci Sports Exerc 39(10) 1867-188 2007

5 White SC Atchison KA Gornbein JA Nattiv A Paganini-Hill A Service SK Risk factors for fracture in older women the Leisure World Cohort Study Gender Medicine 3(2) 110-123 2006

William Oppenheim MD

1 Ali O Shim M Fowler E Cohen P and Oppenheim WSpinal Bone Mineral Density IGF-1 and IGFBP-3 in Children with Cerebral Palsy Hormone Research 2007 Oct 268(6)316-320 [Epub ahead of print]

2 Oppenheim WL Complimentary and Alternative Methods in Cerebral Palsy Dev Med Child Neurol 2009 Oct51 Suppl 4122-9 Review

3 Fowler EG Staudt LA Greenberg MB Oppenheim WLSelective Control Assessment of the Lower Extremity (SCALE) development validation and interrater reliability of a clinical tool for patients with cerebral palsy Dev Med Child Neurol 2009 Aug51(8)607-14 Epub 2009

4 Goldberg EJ Fowler EG Oppenheim WLCase Reports The Influence of Selective Voluntary Motor Control on Gait After Hamstring Lengthening SurgeryClin Orthop Relat Res 2012 May 470(5)1320-6

Robert Pedowitz MD PhD

1 Pedowitz RA Yamaguchi K Ahmad CS Burks RT Flatow EL Green A Ianotti JP Miller BS Tashjian RZ Watters WC 3rd Weber k Turkelson CM Wies JL Anderson S St Andre J Boyer K Raymond L Sluka P McGowan R Optimizing the Management of Rotator Cuff Problems Journal of the American Academy of Orthopaedic Surgeons 19(6)368-79 2011

2 Nofsinger C Browning B Burkhart SS Pedowitz RA Objective preoperative measurement of anterior glenoid bone loss a pilot study of a computer-based method using unilateral 3-dimensional computed tomography Arthroscopy The Journal of Arthroscopic and Related Surgery 27(3)322-9 2011

3 Pedowitz RA Higashigawa K Nguyen V Level V Evidence - The ldquo50 Rulerdquo in Arthroscopic and Orthopaedic Surgery Arthroscopy The Journal of Arthroscopic and Related Surgery 27(11)1584-7 2011

4 Pedowitz RA Commentary amp Perspective Does Every Question Need a Level-I Answer Pragmatic and Ethical Considerations of Clinical Practice Guidelines Journal of Bone and Joint Surgery 94 e13(1-2) 2012

5 Pedowitz RA Marsh JL Motor Skills Training in Orthopaedic Surgery A Paradigm Shift Toward Simulation-Based Educational Curriculum Journal of the American Academy of Orthopaedic Surgeons 20(7)407-9 2012

Frank Petrigliano MD

1 Petrigliano FA Musahl V Citak M Suero E Pearle AP The Effect of Meniscal Loss on Knee Stability After Single-Bundle ACL Reconstructions A Cadaveric Experiment Knee Surg Sports Traumatol Arthrosc 2011 May 12 [Epub ahead of print]

2 Petrigliano FA Suero EM Lane CG Allen AA Pearle AD Combined PCL and Posterolateral Corner Insufficiency Results in a Reverse Pivot Shift Clin Orthop Relat Res 2011 Aug 27 [Epub ahead of print]

25

3 Montgomery SR Petrigliano FA Gamradt SC Biologic augmentation of rotator cuff repair Curr Rev Musculoskelet Med 2011 Aug 19 [Epub ahead of print]

4 Voos JE Suero EM Citak M Petrigliano FA Bosscher MR Citak M Wickiewicz TJ Pearle AP The effect of proximal tibial slope on stability of the anterior cruciate ligament-deficient knee Knee Surg Sports Traumatol Arthrosc 2011 Dec 20

5 Petrigliano FA Suero EM Voos JE Wickiewicz TJ Pearle AP Allen AA The effect of proximal tibial slope on dynamic stability testing of the posterior cruciate ligament- and posterolateral corner-deficient knee Am J Sports Med 2012 Mar 16 [Epub ahead of print]

Anthony Scaduto MD

1 Scaduto AA Hedequist D Chapter 56 Pediatric Spine Orthopaedic Knowledge Update (OKU) 10 Flynn J American Academy of Orthopaedic Surgeons Rosemont IL 2011 pp 87-107

2 Scaduto AA Otsuka N Treatment Options for Leg Length Discrepancy Amputation and Prosthetic Fitting In Management of Limb Length Discrepancy AAOS Monograph American Academy of Orthopaedic Surgeons Hamdy RC (editor) Rosemont Illinois 2011

3 Wren TA Otsuka NY Bowen RE Scaduto AA Chan LS Sheng M Hara R Kay RM Influence of gait analysis on decision-making for lower extremity orthopaedic surgery Baseline data from a randomized trial Gait and Posture 2011 July 34(3) 364-369

4 Bowen RE Gardner S Scaduto AA Eagan M Beckstead J Efficacy of intraoperative cell salvage machines in pediatric spinal deformity surgery Spine 35(2)246-251 January 15 2010

5 Bowen RE Scaduto AA Banuelos S Decreased Body mass index and Restrictive Lung Disease in Congenital Thoracic Scoliosis Journal of Pediatric Orthopaedics 2008 September 28(6)665-668

A Nick Shamie MD

1 Hong SW Lee SH Khoo LT Yoon SH Holly LT Shamie AN Wang JC A Comparison of fixed-hole and slotted-hole dynamic plates for anterior cervical discectomy and fusion J Spinal Disord Tech 2010 Feb23(1)22-6

2 Tsou P Daffner SD Holly LT Shamie AN Wang JC A Comprehensive Subaxial Cervical Spine Injury Severity Assessment Model Using Numeric Scores and Its Predictive Value for Surgical Intervention J Neurotrauma 2011 Oct 12

3 Mikhael M Wolf CF Shamie AN Wang JC Minimally Invasive Techniques for the Posterior Cervical Spine

Foraminal Decompression and Instrumented Fusion Oper Tech Orthop 21240-244 2011

5 Heyrani N Picinic Norheim E Elaine Ku Y Nick Shamie A Interspinous Process Implantation for the Treatment of Neurogenic Intermittent Claudication Anesth Pain 20122(1)36-41

Mauricio Silva MD

1 Spencer H Wong M Fong YJ Penman A Silva M Prospective Longitudinal Evaluation of Elbow Motion Following Pediatric Supracondylar Humerus Fractures J Bone Joint Surg Am 92904-910 2010

2 Bernthal NM Hoshino CM Dichter D Wong MA Silva M Recovery of Range of Motion Following Pediatric Lateral Condyle Fractures of the Humerus J Bone J Surg Am 93-A(9)871-877 2011

3 Pribaz JR Bernthal NM Wong T Silva M Lateral Spurring Following Pediatric Lateral Condyle Fractures J Pediatr Orthop 32(5)456-60 2012

4 Spencer HT Dory FJ Zionts LE Dichter DH Wong MA Moazzaz P Silva M Type II Supracondylar Humerus Fractures Can Some be Treated Non-operatively J Pediatr Orthop 32(7)675-81 2012

5 Silva M Eagan M Wong MA Dichter D Ebramzadeh E Zionts A Comparison of Two Approaches to the Closed Treatment of Low-Energy Tibia Fractures in Children J Bone Joint Surg (Am) 94(20)1845-1852 2012

Nelson SooHoo MD

1 Career Development Award 2009-2013 ldquoVariation in the Quality of Care Patients Undergoing Total Joint Replacementrdquo Orthopaedic Research and Education Foundation

2 SooHoo NF Lieberman JR Farng E Park S Jain S Ko CY Development of quality of care indicators for total joint replacement BMJ Quality Safety 2011 Feb20(2)153-7

3 Fitzgerald J SooHoo NF Losina E Katz JN The potential impact on patient-hospital travel distance and access under a policy of preferential referral to high-volume knee replacement hospitals Arthritis Care Res (Hoboken) 2012 Jun64(6)890-7

4 International Guest Speaker 1st Oriental Congress of Orthopaedics Shanghai China 2012 ldquoUpdate on the treatment of Ankle Arthritis

5 International Guest Speaker Korean Foot and Ankle Society 20th Annual Meeting ldquoEvidence-based treatment of ankle arthritisrdquo Seoul Korea 2011

Bert Thomas MD 1 De Ugarte DA Morizono K Elbarbary A Alfonso Z

Zuk PA Zhu M Dragoo JL Ashjian P Thomas B Benhaim B Chen I Fraser J Hedrick MH

26

2 Comparison of Multi-lineage Cells from Human Adipose and Bone Marrow Cells Tissue and Organs 2003 174101-9

3 Dragoo JL Samimi B Zhu M Hame SL Thomas BJ Lieberman JR Hedrick MH Benhaim P Tissue-Engineered Cartilage and Bone Using Stem Cells From Human Infrapatellar Fat Pads JBJS 2003 85-B740-7

4 Lieberman JR Thomas BJ Finerman GA Dorey F Patientsrsquo Reasons for Undergoing Total Hip Arthroplasty Can Change Over Time J Arthroplasty 2003 Jan 18(1) 63-68

5 Clark CR Huddleston HD Schoch EP and Thomas BJ Leg-Length Discrepancy After Total Hip Arthroplasty JAAOS 2006 14 38 ndash 45

Daniel Vigil MD

1 Vigil DV Heat Illness in Twenty Common Problems in Sports Medicine Puffer JC editor 1st ed New York NY McGraw-Hill 2001 303-21

2 Vigil DV Soccer in Sports Injuries amp Emergencies Rubin AL editor 1st ed New York NY McGraw-Hill 2003 355-61

3 Shah S Vigil DV Luftman JL Stress injury of the talar dome and body in a ballerina a case report J Dance Med Sci 2005 9(3amp4)91-5

4 Ong AL Vigil DV What to do with a heart murmur and hypertension found during a preparticipation physical evaluation Perm Med J Fall 2005 9(4) 20-22

5 Peng HP Vigil DV Ankle Injury ndash Gymnastics Med Sci Sports Exerc 2011 (43)5 Supplement

Jeffrey Wang MD 1 Jeffrey C Wang MD Stephen Yoo BA Linda EA

Kanim MA Patricia A CampbellPhD Arnold Berk MD Jay R Lieberman MD Effect of Regional Gene Therapy with Bone Morphogenetic Protein -2-producing Bone Marrow Cells on Spinal Fusion in Rats The Journal of Bone and Joint Surgery 2003 Vol 85A(5)905-911

2 Miyazaki M Sugiyama O Tow B Zou J Morishita Y Wei F Napoli A Sintuu C Lieberman JR Wang JC The effects of lentiviral gene therapy with bone morphogenetic protein-2-producing bone marrow cells on spinal fusion in rats J Spinal Disord Tech 2008 Jul21(5)372-9

3 Lee KB Murray SS Duarte ME Spitz JF Johnson JS Song KJ Brochmann EJ Taghavi CE Keorochana G Liao JC Wang JC Effects of the bone morphogenetic protein binding protein spp24 (secreted phosphoprotein 24thinspkD) on the growth of human lung cancer cells J Orthop Res 2011 Apr 20 doi 101002jor21383 [Epub ahead of print]

4 Sintuu C Simon RJ Miyazaki M Morishita Y Hymanson HJ Taghavi C Brochmann EJ Murray SS Wang JC Full-Length spp24 but Not Its 185-kDa Proteolytic Fragment Inhibits Bone-Healing in a Rodent Model of Spine Fusion J Bone Joint Surg Am 2011 Jun 193(11)1022-32

5 Lee KB Murray SS Taghavi CE Song KJ Brochmann EJ Johnson JS Keorochana G Liao JC Wang JC Bone morphogenetic proteinndashbinding peptide reduces the inflammatory response to recombinant human bone morphogenetic protein-2 and recombinant human bone morphogenetic protein-7 in a rodent model of soft-tissue inflammation The Spine Journal 11 (2011) 568ndash576

Lewis Zionts MD

1 Zionts LE Zhao G Hitchcock K Maewal J Ebramzadeh E Has the rate of extensive surgery to treat idiopathic clubfoot declined in the United States J Bone Joint Surg Am 201092882-889

2 Zionts LE Dietz FC Post-corrective bracing in the treatment of idiopathic clubfeet using the Ponseti method J Am Acad Orthop Surg 201018486-493

3 Zionts LE Morcuende JA Ebramzadeh E Sangiorgio SN The current management of idiopathic clubfoot revisited Results of a survey of the POSNA membership J Pediatr Orthop 201232515ndash520

4 Zionts LE Frost N Kim R Ebramzadeh E Sangiorgio SN Treatment of idiopathic clubfoot Experience with the Mitchell-Ponseti brace J Pediatr Orthop 201232706-713

5 Silva M Eagan MJ Wong MA Dichter DH Ebramzadeh E Zionts LE Early weight-bearing in the closed treatment of tibial shaft fractures in children J Bone Joint Surg Am 2012941853-1860

27

Alumni Class of 2011 Drs Joshua Bales Brent Berger Adam Bier Michael Eagan Lucie Krenek April Ligato Hillard (Theo) Spencer Class of 2010 Drs Chukwunenye Osuji Samuel Park Payam Moazzaz George Oji Eugene Farng Scott Crow Class of 2009 Drs Anna Cuomo Carlos Gonzalez Devon Jeffcoat Rajeev Pandarinath Frank Petrigliano Shail Vyas Class of 2008 Drs William Carroll III Dara Chafik Augustine Conduah Scott Mitchell Miguel Sandoval Charles Young Class of 2007 Drs Kimberley Caputo Brian Feeley Jason Freedman Wellington Hsu Yekaterina Karpitskaya Class of 2006 Drs Seth Gamradt Katherine Gray Eric Lin Eon Shin Samir Tejiwani Yi-Meng Yen Class of 2005 Drs Kent Jackson Craig Kuhns Brett Peterson Jonathan Roper Stephen Struble Peter Whang Class of 2004 Drs Ethan Alpern Elliot Carlisle Jason Dragoo Yu-Po Lee Rod Payman Brian Rudin Class of 2003 Drs Nitin Bhatia Mark Davies Gary Ghiselli Daniel Oakes Ben Pradhan Jason Zemanovic Class of 2002 Drs Travis Hanson Tze Ip Stephen Nuccion Anthony Scaduto Michael Shepard Stephen Timon Class of 2001 Drs Richard Bowen Matthew Geck Kambiz Hannani John Nassar Edward Sun Erik Zeegen Class of 2000 Drs Janet Baker Aaron Daluiski Brent Davis Mohammed Etminan Paul McDonough Manish Patel

Class of 1999 Drs Hugh Bassewitz Joshua Hatch David Rogers Roger Sun James Ushiba Warren Yu Class of 1998 Drs Kevin Armstrong David Boardman Ward Hamlet Gregory Horner Scott Rosenzweig Scott Smith Class of 1997 Drs Andre Gazdag Mark Henry Michiyuki Kono Edward (Ted) Riley Jr Benjamin Tamm Gary Zohman

Class of 1996 Drs Eric Freedman Robert Kay Vivek Kushwaha Julie Melchior J Scott Smith Jeffrey Wang Class of 1995 Drs Douglas Freedman Thomas Gautsch David Hak Robert Henshaw William Jason David Lamey Philip Wirganowicz Class of 1994 Drs Bruce Bragonier Gregory Chow Craig Davis Karen Johnston-Jones Jeffrey Spychalski Michael Wall Class of 1993 Drs David Hillsgrove James Lubowitz William Luetzow Joe Minchew Alan Moelleken Edward (Ted) Parks Marc Safran Class of 1992 Drs Areesak Chotivichit Emil Dionysian James Gebhard Raymond Severt Peter Romano Tom Thomas Class of 1991 Drs Gregory Duncan Tadashi (Ted) Funahashi Kurt Larson Robert Namba James Nugent William Pfeiffer Lawrence Shin Class of 1990 Drs Avi Bernstein Michael Kody Yu Fon Lee James Leipzig Thomas Schmalzried Class of 1989 Drs David Friscia David Mesna Robert More David Thordarson Class of 1988 Drs David Fisher David Grauer George Lian Stephen Timothy Mar Shoemaker John Skubic Class of 1987 Drs Donald Hales Richard Kahmann Daniel Kaplan Paul Nottingham Tye Ouzounian Robert Wilson Class of 1986 Drs Robert Audell Brian Carney Rick Delamarter Richard Feldman Thomas Grogan Gregory Hanker Riyaz Jinnah Class of 1985 Drs J Randall Davis Steven Ma Richard Marder Steven Schopler Steven Silbart Class of 1984 Drs Michael Bayer Scott Graham Gregory Koski Kirk Lewis Edward Littlejohn Bert Thomas Class of 1983 Drs Lesley Anderson Wayne Christie Timothy Clader Steven Gausewitz Leslie Kim John Rollins Class of 1982 Drs Allan Delman Richard Ferkel Humberto Galleno Frederic Nicola Thomas Roberts

28

ALUMNI UPDATE

The Kaiser Orange County Sports Medicine Fellowship is led by Program Director and residency alumnus Brent Davis MD (below left) Class of 2000 with assistance by sports faculty member and residency alumnus Ted Funahashi MD (below right) Class of 1991 who is also a recent AOA inductee

Class of 1981 Drs Kenneth Baldwin Mark Bernstein David Cherney Roland Dutton Eric Johnson Jan Stehlik Class of 1980 Drs David Bowes Lynn Cooman Adrian Graff-Radford Matthew Lotysch Andrew Shaffer Class of 1979 Drs Jeffrey Eckardt Kevin Ehrhart Jack Purdy Henry Tanz Bruce Watanabe Class of 1978 Drs Maximo Matos William Parker Thomas Pojunas Allen Richardson Norman Sprague III George Thompson Class of 1977 Drs Hans Anderson Marc Friedman Larry Herron Kenton Horacek John Moreland Class of 1976 Drs Richard Bergsrud Paul Feldon Richard Marafioti Michael Newman Class of 1975 Drs Ronald Lamb Joseph Mensch Ronald Perelman Dennis Sakai Class of 1974 Drs Zaven Bilezikjian Robert Cassidy Lawrence Guinney Benjamin Lesin Class of 1973 Drs Warren Harding Robert Irving Class of 1972 Drs Michael Hirsch Kenneth Lay David Schurman Class of 1971 Drs Tom Darrah James Gray Class of 1970 Dr William Loscher Class of 1969 Drs Jerrold Goldman Mark Wellisch Class of 1968 Drs David Culton Mark Hamerling Class of 1967 Drs Thomas Christianson John F Lawrence Class of 1964 Dr Syemour Gassner Class of 1961 Dr Bruce Robinson Class of 1960 Drs William Mullally Robert Watanabe Class of 1958 Dr Robert Horne

ALUMNI UPDATE

The UCSF Sports Medicine Fellowship is led by Program Director and alumnus Brian Feeley MD Class of 2007

29

A Message from former Alumni Director Seth C Gamradt MD

It has been my pleasure to serve as UCLA Orthopaedic Surgeryrsquos first Alumni Director and it is bittersweet leaving this outstanding Department I first came to the Department in 1999 as a fourth year medical student sub-intern from Cornell University Medical College During residency I took advantage of all the program has to offer including outstanding surgical and clinical training as well as the opportunity to spend a year focused on orthopaedic research I would like to thank the entire faculty of the Department who provided outstanding mentorship to me as a resident and accepted me as a colleague when I joined the Sports Medicine Faculty I owe particular thanks to Dr Gerald Finerman who hired me as Chief Resident and has placed tremendous trust in me over the years with the care of UCLA athletes In addition Dr Jeffrey Eckardt has served as a terrific role model for my approach to patient care and I appreciate his guidance and leadership Lastly I thank all of the current and former UCLA Orthopaedic Residents it is an honor to have participated in the education of this exceptional and dedicated group

Sincerely Seth C Gamradt MD Associate Clinical Professor of Orthopaedic Surgery Director of Orthopaedic Athletic Medicine for USC Athletics University of Southern California

Pictured above L-R Dr Richard Marafioti (rsquo76) Dr George Thompson (rsquo77) Mrs Thompson Dr Jeff Eckardt (rsquo79) Dr Tsou Dr Paul Tsou (Faculty) Pictured on right L-R Drs Mark Davies (rsquo03) Dan Oakes (rsquo03) Tony Scaduto (rsquo02) Seth Gamradt (rsquo06) Jason Zemanovic (rsquo03) and Brian Feeley (rsquo07)

Pictures from the AAOS UCLAOH Department of

Orthopaedic Surgery Alumni Reception February 10 2012 San Francisco CA

30

Pictured above L-RDr Richard Marafioti (rsquo76) Dr George Thompson (rsquo77) Mrs Thompson Dr Jeff Eckardt (rsquo79) Dr Tsou Dr Paul Tsou (Faculty) Pictured on right L-R Drs Mark Davies (rsquo03) Dan Oakes (rsquo03) Tony Scaduto (rsquo02) Seth Gamradt (rsquo06) Jason Zemanovic (rsquo03) and Brian Feeley (rsquo07)

Donors to the Orthopaedic Department Resident Education

Alumni Faculty Friends (Since July 2010)

Residents Norman Sprague MD Class of 1978 Jeffrey Eckardt MD Class of 1979Faculty Gregory Koski MD Class of 1984 Tye Ouzounian MD Class of 1987 Andre Gazdag MD Class of 1997 David Boardman MD Class of 1998 Stephen Timon MD Class of 2002 Mark Davies MD Class of 2003 Dan Oakes MD Class of 2003 Brian Feeley MD Class of 2007 Faculty and Friends Gerald Finerman MD Faculty Margot and Thomas Barron Friends Joaquin Fuster MD Friend Walter Jennings MD Friend Theo and Wendy Kolokotrones Friends William Swanson MD Friend

TAX-DEDUCTIBLE DONATIONS By Mail or In Person Please see Pledge Form inside bulletin and make checks payable to The UCLA Foundation Online wwwgivinguclaeduorthopaedicsurgery Contact Kathleen Lago Director UCLA Health Sciences Development (310) 206-3079 klagosupportuclaedu

IN MEMORIAM

Residents

Robert Watanabe MD (1992) Class of 1960

Edgar Dawson MD (2003)

Class of 1971

Ronald Lamb MD Class of 1975

Allen Richardson MD (2003)

Class of 1978

Roderick Smith MD (1977) Class of 1979

Jan Stehlik MD

Class of 1981

David Fisher MD Class of 1988

Sean OrsquoBrien MD (1988)

Class of 1989

Faculty

Charles Bechtol MD (1998) Founding Division Chief 1957-1970

UCLA Orthopaedic Surgery Faculty 1957-1970

Edgar Dawson MD (2003) Founder Orthopaedic Spine Program 1972

UCLA Orthopaedic Surgery Faculty 1972-2003 Class of 1971

Todd Grant MD (1996)

Founder Orthopaedic Oncology Program 1975 UCLA Orthopaedic Surgery Faculty 1973-1978

24

periprosthetic femoral shaft fractures about a stable intramedullary implant Journal of Bone and Joint Surgery Am 200688(Supp 1)275-282

2 Gabbay JS Heller JB Mitchell SA Zuk PA Spoon DB Wasson KL Jarrahy R Benhaim P Bradley JP Osteogenic potentiation of human adipose-derived stem cells in a 3-dimensional matrix Annals of Plastic Surgery 2006 Jul 57(1)89-93

3 Heller JB Gabbay JS Wasson K Mitchell S Heller MM Zuk P Bradley JP Cranial suture response to stress Expression patterns of Noggin and Runx2 Plastic and Reconstructive Surgery 2007 Jun119(7)2037-45

4 Gabbay JS Mitchell SA Alban RF Heller JB Chopra R Feldmar D Nisim AA Kulber D Use of a novel active implant forearm device in treating lateral tendinosis Orthopedics 2007 Dec30(12)1005-9

5 Hartzell TL Benhaim P Imbriglia J Shores J Goitz R Balk M Mitchell S Rubinstein R Gorantla V Schneeberger S Brandacher G Lee WP Azari KK Surgical and Technical Aspects of Hand Transplantation Is it Just Another Replant Hand Clinics 2011 Nov 27(4)521-530

Aurelia Nattiv MD 1 Sugi MT Sheridan K Lewis L Nattiv A Kado DM

Bengs B Active referral intervention following fragility fractures leads to enhanced osteoporosis follow-up care Journal of Osteoporosis vol 2012 2012

2 Arends J Cheung M Barrack M Nattiv A Restoration of menses with nonpharmacologic therapy in collegiate athletes with menstrual disturbances A 5 year retrospective study Int J Sport Nutr Exerc Metab Apr 22(2)98-108 2012

3 Ascenzi M-G Hetzer N Lomovtsev A Rude R Nattiv A Favia A Variation of trabecular architecture in proximal femur of postmenopausal women Journal of Biomechanics 44 (2)248-26 2011

4 Nattiv A [Chair] Loucks A Manore M Sundgot-Borgen J Warren M The American College of Sports Medicine Position Stand on the Female Athlete Triad Med Sci Sports Exerc 39(10) 1867-188 2007

5 White SC Atchison KA Gornbein JA Nattiv A Paganini-Hill A Service SK Risk factors for fracture in older women the Leisure World Cohort Study Gender Medicine 3(2) 110-123 2006

William Oppenheim MD

1 Ali O Shim M Fowler E Cohen P and Oppenheim WSpinal Bone Mineral Density IGF-1 and IGFBP-3 in Children with Cerebral Palsy Hormone Research 2007 Oct 268(6)316-320 [Epub ahead of print]

2 Oppenheim WL Complimentary and Alternative Methods in Cerebral Palsy Dev Med Child Neurol 2009 Oct51 Suppl 4122-9 Review

3 Fowler EG Staudt LA Greenberg MB Oppenheim WLSelective Control Assessment of the Lower Extremity (SCALE) development validation and interrater reliability of a clinical tool for patients with cerebral palsy Dev Med Child Neurol 2009 Aug51(8)607-14 Epub 2009

4 Goldberg EJ Fowler EG Oppenheim WLCase Reports The Influence of Selective Voluntary Motor Control on Gait After Hamstring Lengthening SurgeryClin Orthop Relat Res 2012 May 470(5)1320-6

Robert Pedowitz MD PhD

1 Pedowitz RA Yamaguchi K Ahmad CS Burks RT Flatow EL Green A Ianotti JP Miller BS Tashjian RZ Watters WC 3rd Weber k Turkelson CM Wies JL Anderson S St Andre J Boyer K Raymond L Sluka P McGowan R Optimizing the Management of Rotator Cuff Problems Journal of the American Academy of Orthopaedic Surgeons 19(6)368-79 2011

2 Nofsinger C Browning B Burkhart SS Pedowitz RA Objective preoperative measurement of anterior glenoid bone loss a pilot study of a computer-based method using unilateral 3-dimensional computed tomography Arthroscopy The Journal of Arthroscopic and Related Surgery 27(3)322-9 2011

3 Pedowitz RA Higashigawa K Nguyen V Level V Evidence - The ldquo50 Rulerdquo in Arthroscopic and Orthopaedic Surgery Arthroscopy The Journal of Arthroscopic and Related Surgery 27(11)1584-7 2011

4 Pedowitz RA Commentary amp Perspective Does Every Question Need a Level-I Answer Pragmatic and Ethical Considerations of Clinical Practice Guidelines Journal of Bone and Joint Surgery 94 e13(1-2) 2012

5 Pedowitz RA Marsh JL Motor Skills Training in Orthopaedic Surgery A Paradigm Shift Toward Simulation-Based Educational Curriculum Journal of the American Academy of Orthopaedic Surgeons 20(7)407-9 2012

Frank Petrigliano MD

1 Petrigliano FA Musahl V Citak M Suero E Pearle AP The Effect of Meniscal Loss on Knee Stability After Single-Bundle ACL Reconstructions A Cadaveric Experiment Knee Surg Sports Traumatol Arthrosc 2011 May 12 [Epub ahead of print]

2 Petrigliano FA Suero EM Lane CG Allen AA Pearle AD Combined PCL and Posterolateral Corner Insufficiency Results in a Reverse Pivot Shift Clin Orthop Relat Res 2011 Aug 27 [Epub ahead of print]

25

3 Montgomery SR Petrigliano FA Gamradt SC Biologic augmentation of rotator cuff repair Curr Rev Musculoskelet Med 2011 Aug 19 [Epub ahead of print]

4 Voos JE Suero EM Citak M Petrigliano FA Bosscher MR Citak M Wickiewicz TJ Pearle AP The effect of proximal tibial slope on stability of the anterior cruciate ligament-deficient knee Knee Surg Sports Traumatol Arthrosc 2011 Dec 20

5 Petrigliano FA Suero EM Voos JE Wickiewicz TJ Pearle AP Allen AA The effect of proximal tibial slope on dynamic stability testing of the posterior cruciate ligament- and posterolateral corner-deficient knee Am J Sports Med 2012 Mar 16 [Epub ahead of print]

Anthony Scaduto MD

1 Scaduto AA Hedequist D Chapter 56 Pediatric Spine Orthopaedic Knowledge Update (OKU) 10 Flynn J American Academy of Orthopaedic Surgeons Rosemont IL 2011 pp 87-107

2 Scaduto AA Otsuka N Treatment Options for Leg Length Discrepancy Amputation and Prosthetic Fitting In Management of Limb Length Discrepancy AAOS Monograph American Academy of Orthopaedic Surgeons Hamdy RC (editor) Rosemont Illinois 2011

3 Wren TA Otsuka NY Bowen RE Scaduto AA Chan LS Sheng M Hara R Kay RM Influence of gait analysis on decision-making for lower extremity orthopaedic surgery Baseline data from a randomized trial Gait and Posture 2011 July 34(3) 364-369

4 Bowen RE Gardner S Scaduto AA Eagan M Beckstead J Efficacy of intraoperative cell salvage machines in pediatric spinal deformity surgery Spine 35(2)246-251 January 15 2010

5 Bowen RE Scaduto AA Banuelos S Decreased Body mass index and Restrictive Lung Disease in Congenital Thoracic Scoliosis Journal of Pediatric Orthopaedics 2008 September 28(6)665-668

A Nick Shamie MD

1 Hong SW Lee SH Khoo LT Yoon SH Holly LT Shamie AN Wang JC A Comparison of fixed-hole and slotted-hole dynamic plates for anterior cervical discectomy and fusion J Spinal Disord Tech 2010 Feb23(1)22-6

2 Tsou P Daffner SD Holly LT Shamie AN Wang JC A Comprehensive Subaxial Cervical Spine Injury Severity Assessment Model Using Numeric Scores and Its Predictive Value for Surgical Intervention J Neurotrauma 2011 Oct 12

3 Mikhael M Wolf CF Shamie AN Wang JC Minimally Invasive Techniques for the Posterior Cervical Spine

Foraminal Decompression and Instrumented Fusion Oper Tech Orthop 21240-244 2011

5 Heyrani N Picinic Norheim E Elaine Ku Y Nick Shamie A Interspinous Process Implantation for the Treatment of Neurogenic Intermittent Claudication Anesth Pain 20122(1)36-41

Mauricio Silva MD

1 Spencer H Wong M Fong YJ Penman A Silva M Prospective Longitudinal Evaluation of Elbow Motion Following Pediatric Supracondylar Humerus Fractures J Bone Joint Surg Am 92904-910 2010

2 Bernthal NM Hoshino CM Dichter D Wong MA Silva M Recovery of Range of Motion Following Pediatric Lateral Condyle Fractures of the Humerus J Bone J Surg Am 93-A(9)871-877 2011

3 Pribaz JR Bernthal NM Wong T Silva M Lateral Spurring Following Pediatric Lateral Condyle Fractures J Pediatr Orthop 32(5)456-60 2012

4 Spencer HT Dory FJ Zionts LE Dichter DH Wong MA Moazzaz P Silva M Type II Supracondylar Humerus Fractures Can Some be Treated Non-operatively J Pediatr Orthop 32(7)675-81 2012

5 Silva M Eagan M Wong MA Dichter D Ebramzadeh E Zionts A Comparison of Two Approaches to the Closed Treatment of Low-Energy Tibia Fractures in Children J Bone Joint Surg (Am) 94(20)1845-1852 2012

Nelson SooHoo MD

1 Career Development Award 2009-2013 ldquoVariation in the Quality of Care Patients Undergoing Total Joint Replacementrdquo Orthopaedic Research and Education Foundation

2 SooHoo NF Lieberman JR Farng E Park S Jain S Ko CY Development of quality of care indicators for total joint replacement BMJ Quality Safety 2011 Feb20(2)153-7

3 Fitzgerald J SooHoo NF Losina E Katz JN The potential impact on patient-hospital travel distance and access under a policy of preferential referral to high-volume knee replacement hospitals Arthritis Care Res (Hoboken) 2012 Jun64(6)890-7

4 International Guest Speaker 1st Oriental Congress of Orthopaedics Shanghai China 2012 ldquoUpdate on the treatment of Ankle Arthritis

5 International Guest Speaker Korean Foot and Ankle Society 20th Annual Meeting ldquoEvidence-based treatment of ankle arthritisrdquo Seoul Korea 2011

Bert Thomas MD 1 De Ugarte DA Morizono K Elbarbary A Alfonso Z

Zuk PA Zhu M Dragoo JL Ashjian P Thomas B Benhaim B Chen I Fraser J Hedrick MH

26

2 Comparison of Multi-lineage Cells from Human Adipose and Bone Marrow Cells Tissue and Organs 2003 174101-9

3 Dragoo JL Samimi B Zhu M Hame SL Thomas BJ Lieberman JR Hedrick MH Benhaim P Tissue-Engineered Cartilage and Bone Using Stem Cells From Human Infrapatellar Fat Pads JBJS 2003 85-B740-7

4 Lieberman JR Thomas BJ Finerman GA Dorey F Patientsrsquo Reasons for Undergoing Total Hip Arthroplasty Can Change Over Time J Arthroplasty 2003 Jan 18(1) 63-68

5 Clark CR Huddleston HD Schoch EP and Thomas BJ Leg-Length Discrepancy After Total Hip Arthroplasty JAAOS 2006 14 38 ndash 45

Daniel Vigil MD

1 Vigil DV Heat Illness in Twenty Common Problems in Sports Medicine Puffer JC editor 1st ed New York NY McGraw-Hill 2001 303-21

2 Vigil DV Soccer in Sports Injuries amp Emergencies Rubin AL editor 1st ed New York NY McGraw-Hill 2003 355-61

3 Shah S Vigil DV Luftman JL Stress injury of the talar dome and body in a ballerina a case report J Dance Med Sci 2005 9(3amp4)91-5

4 Ong AL Vigil DV What to do with a heart murmur and hypertension found during a preparticipation physical evaluation Perm Med J Fall 2005 9(4) 20-22

5 Peng HP Vigil DV Ankle Injury ndash Gymnastics Med Sci Sports Exerc 2011 (43)5 Supplement

Jeffrey Wang MD 1 Jeffrey C Wang MD Stephen Yoo BA Linda EA

Kanim MA Patricia A CampbellPhD Arnold Berk MD Jay R Lieberman MD Effect of Regional Gene Therapy with Bone Morphogenetic Protein -2-producing Bone Marrow Cells on Spinal Fusion in Rats The Journal of Bone and Joint Surgery 2003 Vol 85A(5)905-911

2 Miyazaki M Sugiyama O Tow B Zou J Morishita Y Wei F Napoli A Sintuu C Lieberman JR Wang JC The effects of lentiviral gene therapy with bone morphogenetic protein-2-producing bone marrow cells on spinal fusion in rats J Spinal Disord Tech 2008 Jul21(5)372-9

3 Lee KB Murray SS Duarte ME Spitz JF Johnson JS Song KJ Brochmann EJ Taghavi CE Keorochana G Liao JC Wang JC Effects of the bone morphogenetic protein binding protein spp24 (secreted phosphoprotein 24thinspkD) on the growth of human lung cancer cells J Orthop Res 2011 Apr 20 doi 101002jor21383 [Epub ahead of print]

4 Sintuu C Simon RJ Miyazaki M Morishita Y Hymanson HJ Taghavi C Brochmann EJ Murray SS Wang JC Full-Length spp24 but Not Its 185-kDa Proteolytic Fragment Inhibits Bone-Healing in a Rodent Model of Spine Fusion J Bone Joint Surg Am 2011 Jun 193(11)1022-32

5 Lee KB Murray SS Taghavi CE Song KJ Brochmann EJ Johnson JS Keorochana G Liao JC Wang JC Bone morphogenetic proteinndashbinding peptide reduces the inflammatory response to recombinant human bone morphogenetic protein-2 and recombinant human bone morphogenetic protein-7 in a rodent model of soft-tissue inflammation The Spine Journal 11 (2011) 568ndash576

Lewis Zionts MD

1 Zionts LE Zhao G Hitchcock K Maewal J Ebramzadeh E Has the rate of extensive surgery to treat idiopathic clubfoot declined in the United States J Bone Joint Surg Am 201092882-889

2 Zionts LE Dietz FC Post-corrective bracing in the treatment of idiopathic clubfeet using the Ponseti method J Am Acad Orthop Surg 201018486-493

3 Zionts LE Morcuende JA Ebramzadeh E Sangiorgio SN The current management of idiopathic clubfoot revisited Results of a survey of the POSNA membership J Pediatr Orthop 201232515ndash520

4 Zionts LE Frost N Kim R Ebramzadeh E Sangiorgio SN Treatment of idiopathic clubfoot Experience with the Mitchell-Ponseti brace J Pediatr Orthop 201232706-713

5 Silva M Eagan MJ Wong MA Dichter DH Ebramzadeh E Zionts LE Early weight-bearing in the closed treatment of tibial shaft fractures in children J Bone Joint Surg Am 2012941853-1860

27

Alumni Class of 2011 Drs Joshua Bales Brent Berger Adam Bier Michael Eagan Lucie Krenek April Ligato Hillard (Theo) Spencer Class of 2010 Drs Chukwunenye Osuji Samuel Park Payam Moazzaz George Oji Eugene Farng Scott Crow Class of 2009 Drs Anna Cuomo Carlos Gonzalez Devon Jeffcoat Rajeev Pandarinath Frank Petrigliano Shail Vyas Class of 2008 Drs William Carroll III Dara Chafik Augustine Conduah Scott Mitchell Miguel Sandoval Charles Young Class of 2007 Drs Kimberley Caputo Brian Feeley Jason Freedman Wellington Hsu Yekaterina Karpitskaya Class of 2006 Drs Seth Gamradt Katherine Gray Eric Lin Eon Shin Samir Tejiwani Yi-Meng Yen Class of 2005 Drs Kent Jackson Craig Kuhns Brett Peterson Jonathan Roper Stephen Struble Peter Whang Class of 2004 Drs Ethan Alpern Elliot Carlisle Jason Dragoo Yu-Po Lee Rod Payman Brian Rudin Class of 2003 Drs Nitin Bhatia Mark Davies Gary Ghiselli Daniel Oakes Ben Pradhan Jason Zemanovic Class of 2002 Drs Travis Hanson Tze Ip Stephen Nuccion Anthony Scaduto Michael Shepard Stephen Timon Class of 2001 Drs Richard Bowen Matthew Geck Kambiz Hannani John Nassar Edward Sun Erik Zeegen Class of 2000 Drs Janet Baker Aaron Daluiski Brent Davis Mohammed Etminan Paul McDonough Manish Patel

Class of 1999 Drs Hugh Bassewitz Joshua Hatch David Rogers Roger Sun James Ushiba Warren Yu Class of 1998 Drs Kevin Armstrong David Boardman Ward Hamlet Gregory Horner Scott Rosenzweig Scott Smith Class of 1997 Drs Andre Gazdag Mark Henry Michiyuki Kono Edward (Ted) Riley Jr Benjamin Tamm Gary Zohman

Class of 1996 Drs Eric Freedman Robert Kay Vivek Kushwaha Julie Melchior J Scott Smith Jeffrey Wang Class of 1995 Drs Douglas Freedman Thomas Gautsch David Hak Robert Henshaw William Jason David Lamey Philip Wirganowicz Class of 1994 Drs Bruce Bragonier Gregory Chow Craig Davis Karen Johnston-Jones Jeffrey Spychalski Michael Wall Class of 1993 Drs David Hillsgrove James Lubowitz William Luetzow Joe Minchew Alan Moelleken Edward (Ted) Parks Marc Safran Class of 1992 Drs Areesak Chotivichit Emil Dionysian James Gebhard Raymond Severt Peter Romano Tom Thomas Class of 1991 Drs Gregory Duncan Tadashi (Ted) Funahashi Kurt Larson Robert Namba James Nugent William Pfeiffer Lawrence Shin Class of 1990 Drs Avi Bernstein Michael Kody Yu Fon Lee James Leipzig Thomas Schmalzried Class of 1989 Drs David Friscia David Mesna Robert More David Thordarson Class of 1988 Drs David Fisher David Grauer George Lian Stephen Timothy Mar Shoemaker John Skubic Class of 1987 Drs Donald Hales Richard Kahmann Daniel Kaplan Paul Nottingham Tye Ouzounian Robert Wilson Class of 1986 Drs Robert Audell Brian Carney Rick Delamarter Richard Feldman Thomas Grogan Gregory Hanker Riyaz Jinnah Class of 1985 Drs J Randall Davis Steven Ma Richard Marder Steven Schopler Steven Silbart Class of 1984 Drs Michael Bayer Scott Graham Gregory Koski Kirk Lewis Edward Littlejohn Bert Thomas Class of 1983 Drs Lesley Anderson Wayne Christie Timothy Clader Steven Gausewitz Leslie Kim John Rollins Class of 1982 Drs Allan Delman Richard Ferkel Humberto Galleno Frederic Nicola Thomas Roberts

28

ALUMNI UPDATE

The Kaiser Orange County Sports Medicine Fellowship is led by Program Director and residency alumnus Brent Davis MD (below left) Class of 2000 with assistance by sports faculty member and residency alumnus Ted Funahashi MD (below right) Class of 1991 who is also a recent AOA inductee

Class of 1981 Drs Kenneth Baldwin Mark Bernstein David Cherney Roland Dutton Eric Johnson Jan Stehlik Class of 1980 Drs David Bowes Lynn Cooman Adrian Graff-Radford Matthew Lotysch Andrew Shaffer Class of 1979 Drs Jeffrey Eckardt Kevin Ehrhart Jack Purdy Henry Tanz Bruce Watanabe Class of 1978 Drs Maximo Matos William Parker Thomas Pojunas Allen Richardson Norman Sprague III George Thompson Class of 1977 Drs Hans Anderson Marc Friedman Larry Herron Kenton Horacek John Moreland Class of 1976 Drs Richard Bergsrud Paul Feldon Richard Marafioti Michael Newman Class of 1975 Drs Ronald Lamb Joseph Mensch Ronald Perelman Dennis Sakai Class of 1974 Drs Zaven Bilezikjian Robert Cassidy Lawrence Guinney Benjamin Lesin Class of 1973 Drs Warren Harding Robert Irving Class of 1972 Drs Michael Hirsch Kenneth Lay David Schurman Class of 1971 Drs Tom Darrah James Gray Class of 1970 Dr William Loscher Class of 1969 Drs Jerrold Goldman Mark Wellisch Class of 1968 Drs David Culton Mark Hamerling Class of 1967 Drs Thomas Christianson John F Lawrence Class of 1964 Dr Syemour Gassner Class of 1961 Dr Bruce Robinson Class of 1960 Drs William Mullally Robert Watanabe Class of 1958 Dr Robert Horne

ALUMNI UPDATE

The UCSF Sports Medicine Fellowship is led by Program Director and alumnus Brian Feeley MD Class of 2007

29

A Message from former Alumni Director Seth C Gamradt MD

It has been my pleasure to serve as UCLA Orthopaedic Surgeryrsquos first Alumni Director and it is bittersweet leaving this outstanding Department I first came to the Department in 1999 as a fourth year medical student sub-intern from Cornell University Medical College During residency I took advantage of all the program has to offer including outstanding surgical and clinical training as well as the opportunity to spend a year focused on orthopaedic research I would like to thank the entire faculty of the Department who provided outstanding mentorship to me as a resident and accepted me as a colleague when I joined the Sports Medicine Faculty I owe particular thanks to Dr Gerald Finerman who hired me as Chief Resident and has placed tremendous trust in me over the years with the care of UCLA athletes In addition Dr Jeffrey Eckardt has served as a terrific role model for my approach to patient care and I appreciate his guidance and leadership Lastly I thank all of the current and former UCLA Orthopaedic Residents it is an honor to have participated in the education of this exceptional and dedicated group

Sincerely Seth C Gamradt MD Associate Clinical Professor of Orthopaedic Surgery Director of Orthopaedic Athletic Medicine for USC Athletics University of Southern California

Pictured above L-R Dr Richard Marafioti (rsquo76) Dr George Thompson (rsquo77) Mrs Thompson Dr Jeff Eckardt (rsquo79) Dr Tsou Dr Paul Tsou (Faculty) Pictured on right L-R Drs Mark Davies (rsquo03) Dan Oakes (rsquo03) Tony Scaduto (rsquo02) Seth Gamradt (rsquo06) Jason Zemanovic (rsquo03) and Brian Feeley (rsquo07)

Pictures from the AAOS UCLAOH Department of

Orthopaedic Surgery Alumni Reception February 10 2012 San Francisco CA

30

Pictured above L-RDr Richard Marafioti (rsquo76) Dr George Thompson (rsquo77) Mrs Thompson Dr Jeff Eckardt (rsquo79) Dr Tsou Dr Paul Tsou (Faculty) Pictured on right L-R Drs Mark Davies (rsquo03) Dan Oakes (rsquo03) Tony Scaduto (rsquo02) Seth Gamradt (rsquo06) Jason Zemanovic (rsquo03) and Brian Feeley (rsquo07)

Donors to the Orthopaedic Department Resident Education

Alumni Faculty Friends (Since July 2010)

Residents Norman Sprague MD Class of 1978 Jeffrey Eckardt MD Class of 1979Faculty Gregory Koski MD Class of 1984 Tye Ouzounian MD Class of 1987 Andre Gazdag MD Class of 1997 David Boardman MD Class of 1998 Stephen Timon MD Class of 2002 Mark Davies MD Class of 2003 Dan Oakes MD Class of 2003 Brian Feeley MD Class of 2007 Faculty and Friends Gerald Finerman MD Faculty Margot and Thomas Barron Friends Joaquin Fuster MD Friend Walter Jennings MD Friend Theo and Wendy Kolokotrones Friends William Swanson MD Friend

TAX-DEDUCTIBLE DONATIONS By Mail or In Person Please see Pledge Form inside bulletin and make checks payable to The UCLA Foundation Online wwwgivinguclaeduorthopaedicsurgery Contact Kathleen Lago Director UCLA Health Sciences Development (310) 206-3079 klagosupportuclaedu

IN MEMORIAM

Residents

Robert Watanabe MD (1992) Class of 1960

Edgar Dawson MD (2003)

Class of 1971

Ronald Lamb MD Class of 1975

Allen Richardson MD (2003)

Class of 1978

Roderick Smith MD (1977) Class of 1979

Jan Stehlik MD

Class of 1981

David Fisher MD Class of 1988

Sean OrsquoBrien MD (1988)

Class of 1989

Faculty

Charles Bechtol MD (1998) Founding Division Chief 1957-1970

UCLA Orthopaedic Surgery Faculty 1957-1970

Edgar Dawson MD (2003) Founder Orthopaedic Spine Program 1972

UCLA Orthopaedic Surgery Faculty 1972-2003 Class of 1971

Todd Grant MD (1996)

Founder Orthopaedic Oncology Program 1975 UCLA Orthopaedic Surgery Faculty 1973-1978

25

3 Montgomery SR Petrigliano FA Gamradt SC Biologic augmentation of rotator cuff repair Curr Rev Musculoskelet Med 2011 Aug 19 [Epub ahead of print]

4 Voos JE Suero EM Citak M Petrigliano FA Bosscher MR Citak M Wickiewicz TJ Pearle AP The effect of proximal tibial slope on stability of the anterior cruciate ligament-deficient knee Knee Surg Sports Traumatol Arthrosc 2011 Dec 20

5 Petrigliano FA Suero EM Voos JE Wickiewicz TJ Pearle AP Allen AA The effect of proximal tibial slope on dynamic stability testing of the posterior cruciate ligament- and posterolateral corner-deficient knee Am J Sports Med 2012 Mar 16 [Epub ahead of print]

Anthony Scaduto MD

1 Scaduto AA Hedequist D Chapter 56 Pediatric Spine Orthopaedic Knowledge Update (OKU) 10 Flynn J American Academy of Orthopaedic Surgeons Rosemont IL 2011 pp 87-107

2 Scaduto AA Otsuka N Treatment Options for Leg Length Discrepancy Amputation and Prosthetic Fitting In Management of Limb Length Discrepancy AAOS Monograph American Academy of Orthopaedic Surgeons Hamdy RC (editor) Rosemont Illinois 2011

3 Wren TA Otsuka NY Bowen RE Scaduto AA Chan LS Sheng M Hara R Kay RM Influence of gait analysis on decision-making for lower extremity orthopaedic surgery Baseline data from a randomized trial Gait and Posture 2011 July 34(3) 364-369

4 Bowen RE Gardner S Scaduto AA Eagan M Beckstead J Efficacy of intraoperative cell salvage machines in pediatric spinal deformity surgery Spine 35(2)246-251 January 15 2010

5 Bowen RE Scaduto AA Banuelos S Decreased Body mass index and Restrictive Lung Disease in Congenital Thoracic Scoliosis Journal of Pediatric Orthopaedics 2008 September 28(6)665-668

A Nick Shamie MD

1 Hong SW Lee SH Khoo LT Yoon SH Holly LT Shamie AN Wang JC A Comparison of fixed-hole and slotted-hole dynamic plates for anterior cervical discectomy and fusion J Spinal Disord Tech 2010 Feb23(1)22-6

2 Tsou P Daffner SD Holly LT Shamie AN Wang JC A Comprehensive Subaxial Cervical Spine Injury Severity Assessment Model Using Numeric Scores and Its Predictive Value for Surgical Intervention J Neurotrauma 2011 Oct 12

3 Mikhael M Wolf CF Shamie AN Wang JC Minimally Invasive Techniques for the Posterior Cervical Spine

Foraminal Decompression and Instrumented Fusion Oper Tech Orthop 21240-244 2011

5 Heyrani N Picinic Norheim E Elaine Ku Y Nick Shamie A Interspinous Process Implantation for the Treatment of Neurogenic Intermittent Claudication Anesth Pain 20122(1)36-41

Mauricio Silva MD

1 Spencer H Wong M Fong YJ Penman A Silva M Prospective Longitudinal Evaluation of Elbow Motion Following Pediatric Supracondylar Humerus Fractures J Bone Joint Surg Am 92904-910 2010

2 Bernthal NM Hoshino CM Dichter D Wong MA Silva M Recovery of Range of Motion Following Pediatric Lateral Condyle Fractures of the Humerus J Bone J Surg Am 93-A(9)871-877 2011

3 Pribaz JR Bernthal NM Wong T Silva M Lateral Spurring Following Pediatric Lateral Condyle Fractures J Pediatr Orthop 32(5)456-60 2012

4 Spencer HT Dory FJ Zionts LE Dichter DH Wong MA Moazzaz P Silva M Type II Supracondylar Humerus Fractures Can Some be Treated Non-operatively J Pediatr Orthop 32(7)675-81 2012

5 Silva M Eagan M Wong MA Dichter D Ebramzadeh E Zionts A Comparison of Two Approaches to the Closed Treatment of Low-Energy Tibia Fractures in Children J Bone Joint Surg (Am) 94(20)1845-1852 2012

Nelson SooHoo MD

1 Career Development Award 2009-2013 ldquoVariation in the Quality of Care Patients Undergoing Total Joint Replacementrdquo Orthopaedic Research and Education Foundation

2 SooHoo NF Lieberman JR Farng E Park S Jain S Ko CY Development of quality of care indicators for total joint replacement BMJ Quality Safety 2011 Feb20(2)153-7

3 Fitzgerald J SooHoo NF Losina E Katz JN The potential impact on patient-hospital travel distance and access under a policy of preferential referral to high-volume knee replacement hospitals Arthritis Care Res (Hoboken) 2012 Jun64(6)890-7

4 International Guest Speaker 1st Oriental Congress of Orthopaedics Shanghai China 2012 ldquoUpdate on the treatment of Ankle Arthritis

5 International Guest Speaker Korean Foot and Ankle Society 20th Annual Meeting ldquoEvidence-based treatment of ankle arthritisrdquo Seoul Korea 2011

Bert Thomas MD 1 De Ugarte DA Morizono K Elbarbary A Alfonso Z

Zuk PA Zhu M Dragoo JL Ashjian P Thomas B Benhaim B Chen I Fraser J Hedrick MH

26

2 Comparison of Multi-lineage Cells from Human Adipose and Bone Marrow Cells Tissue and Organs 2003 174101-9

3 Dragoo JL Samimi B Zhu M Hame SL Thomas BJ Lieberman JR Hedrick MH Benhaim P Tissue-Engineered Cartilage and Bone Using Stem Cells From Human Infrapatellar Fat Pads JBJS 2003 85-B740-7

4 Lieberman JR Thomas BJ Finerman GA Dorey F Patientsrsquo Reasons for Undergoing Total Hip Arthroplasty Can Change Over Time J Arthroplasty 2003 Jan 18(1) 63-68

5 Clark CR Huddleston HD Schoch EP and Thomas BJ Leg-Length Discrepancy After Total Hip Arthroplasty JAAOS 2006 14 38 ndash 45

Daniel Vigil MD

1 Vigil DV Heat Illness in Twenty Common Problems in Sports Medicine Puffer JC editor 1st ed New York NY McGraw-Hill 2001 303-21

2 Vigil DV Soccer in Sports Injuries amp Emergencies Rubin AL editor 1st ed New York NY McGraw-Hill 2003 355-61

3 Shah S Vigil DV Luftman JL Stress injury of the talar dome and body in a ballerina a case report J Dance Med Sci 2005 9(3amp4)91-5

4 Ong AL Vigil DV What to do with a heart murmur and hypertension found during a preparticipation physical evaluation Perm Med J Fall 2005 9(4) 20-22

5 Peng HP Vigil DV Ankle Injury ndash Gymnastics Med Sci Sports Exerc 2011 (43)5 Supplement

Jeffrey Wang MD 1 Jeffrey C Wang MD Stephen Yoo BA Linda EA

Kanim MA Patricia A CampbellPhD Arnold Berk MD Jay R Lieberman MD Effect of Regional Gene Therapy with Bone Morphogenetic Protein -2-producing Bone Marrow Cells on Spinal Fusion in Rats The Journal of Bone and Joint Surgery 2003 Vol 85A(5)905-911

2 Miyazaki M Sugiyama O Tow B Zou J Morishita Y Wei F Napoli A Sintuu C Lieberman JR Wang JC The effects of lentiviral gene therapy with bone morphogenetic protein-2-producing bone marrow cells on spinal fusion in rats J Spinal Disord Tech 2008 Jul21(5)372-9

3 Lee KB Murray SS Duarte ME Spitz JF Johnson JS Song KJ Brochmann EJ Taghavi CE Keorochana G Liao JC Wang JC Effects of the bone morphogenetic protein binding protein spp24 (secreted phosphoprotein 24thinspkD) on the growth of human lung cancer cells J Orthop Res 2011 Apr 20 doi 101002jor21383 [Epub ahead of print]

4 Sintuu C Simon RJ Miyazaki M Morishita Y Hymanson HJ Taghavi C Brochmann EJ Murray SS Wang JC Full-Length spp24 but Not Its 185-kDa Proteolytic Fragment Inhibits Bone-Healing in a Rodent Model of Spine Fusion J Bone Joint Surg Am 2011 Jun 193(11)1022-32

5 Lee KB Murray SS Taghavi CE Song KJ Brochmann EJ Johnson JS Keorochana G Liao JC Wang JC Bone morphogenetic proteinndashbinding peptide reduces the inflammatory response to recombinant human bone morphogenetic protein-2 and recombinant human bone morphogenetic protein-7 in a rodent model of soft-tissue inflammation The Spine Journal 11 (2011) 568ndash576

Lewis Zionts MD

1 Zionts LE Zhao G Hitchcock K Maewal J Ebramzadeh E Has the rate of extensive surgery to treat idiopathic clubfoot declined in the United States J Bone Joint Surg Am 201092882-889

2 Zionts LE Dietz FC Post-corrective bracing in the treatment of idiopathic clubfeet using the Ponseti method J Am Acad Orthop Surg 201018486-493

3 Zionts LE Morcuende JA Ebramzadeh E Sangiorgio SN The current management of idiopathic clubfoot revisited Results of a survey of the POSNA membership J Pediatr Orthop 201232515ndash520

4 Zionts LE Frost N Kim R Ebramzadeh E Sangiorgio SN Treatment of idiopathic clubfoot Experience with the Mitchell-Ponseti brace J Pediatr Orthop 201232706-713

5 Silva M Eagan MJ Wong MA Dichter DH Ebramzadeh E Zionts LE Early weight-bearing in the closed treatment of tibial shaft fractures in children J Bone Joint Surg Am 2012941853-1860

27

Alumni Class of 2011 Drs Joshua Bales Brent Berger Adam Bier Michael Eagan Lucie Krenek April Ligato Hillard (Theo) Spencer Class of 2010 Drs Chukwunenye Osuji Samuel Park Payam Moazzaz George Oji Eugene Farng Scott Crow Class of 2009 Drs Anna Cuomo Carlos Gonzalez Devon Jeffcoat Rajeev Pandarinath Frank Petrigliano Shail Vyas Class of 2008 Drs William Carroll III Dara Chafik Augustine Conduah Scott Mitchell Miguel Sandoval Charles Young Class of 2007 Drs Kimberley Caputo Brian Feeley Jason Freedman Wellington Hsu Yekaterina Karpitskaya Class of 2006 Drs Seth Gamradt Katherine Gray Eric Lin Eon Shin Samir Tejiwani Yi-Meng Yen Class of 2005 Drs Kent Jackson Craig Kuhns Brett Peterson Jonathan Roper Stephen Struble Peter Whang Class of 2004 Drs Ethan Alpern Elliot Carlisle Jason Dragoo Yu-Po Lee Rod Payman Brian Rudin Class of 2003 Drs Nitin Bhatia Mark Davies Gary Ghiselli Daniel Oakes Ben Pradhan Jason Zemanovic Class of 2002 Drs Travis Hanson Tze Ip Stephen Nuccion Anthony Scaduto Michael Shepard Stephen Timon Class of 2001 Drs Richard Bowen Matthew Geck Kambiz Hannani John Nassar Edward Sun Erik Zeegen Class of 2000 Drs Janet Baker Aaron Daluiski Brent Davis Mohammed Etminan Paul McDonough Manish Patel

Class of 1999 Drs Hugh Bassewitz Joshua Hatch David Rogers Roger Sun James Ushiba Warren Yu Class of 1998 Drs Kevin Armstrong David Boardman Ward Hamlet Gregory Horner Scott Rosenzweig Scott Smith Class of 1997 Drs Andre Gazdag Mark Henry Michiyuki Kono Edward (Ted) Riley Jr Benjamin Tamm Gary Zohman

Class of 1996 Drs Eric Freedman Robert Kay Vivek Kushwaha Julie Melchior J Scott Smith Jeffrey Wang Class of 1995 Drs Douglas Freedman Thomas Gautsch David Hak Robert Henshaw William Jason David Lamey Philip Wirganowicz Class of 1994 Drs Bruce Bragonier Gregory Chow Craig Davis Karen Johnston-Jones Jeffrey Spychalski Michael Wall Class of 1993 Drs David Hillsgrove James Lubowitz William Luetzow Joe Minchew Alan Moelleken Edward (Ted) Parks Marc Safran Class of 1992 Drs Areesak Chotivichit Emil Dionysian James Gebhard Raymond Severt Peter Romano Tom Thomas Class of 1991 Drs Gregory Duncan Tadashi (Ted) Funahashi Kurt Larson Robert Namba James Nugent William Pfeiffer Lawrence Shin Class of 1990 Drs Avi Bernstein Michael Kody Yu Fon Lee James Leipzig Thomas Schmalzried Class of 1989 Drs David Friscia David Mesna Robert More David Thordarson Class of 1988 Drs David Fisher David Grauer George Lian Stephen Timothy Mar Shoemaker John Skubic Class of 1987 Drs Donald Hales Richard Kahmann Daniel Kaplan Paul Nottingham Tye Ouzounian Robert Wilson Class of 1986 Drs Robert Audell Brian Carney Rick Delamarter Richard Feldman Thomas Grogan Gregory Hanker Riyaz Jinnah Class of 1985 Drs J Randall Davis Steven Ma Richard Marder Steven Schopler Steven Silbart Class of 1984 Drs Michael Bayer Scott Graham Gregory Koski Kirk Lewis Edward Littlejohn Bert Thomas Class of 1983 Drs Lesley Anderson Wayne Christie Timothy Clader Steven Gausewitz Leslie Kim John Rollins Class of 1982 Drs Allan Delman Richard Ferkel Humberto Galleno Frederic Nicola Thomas Roberts

28

ALUMNI UPDATE

The Kaiser Orange County Sports Medicine Fellowship is led by Program Director and residency alumnus Brent Davis MD (below left) Class of 2000 with assistance by sports faculty member and residency alumnus Ted Funahashi MD (below right) Class of 1991 who is also a recent AOA inductee

Class of 1981 Drs Kenneth Baldwin Mark Bernstein David Cherney Roland Dutton Eric Johnson Jan Stehlik Class of 1980 Drs David Bowes Lynn Cooman Adrian Graff-Radford Matthew Lotysch Andrew Shaffer Class of 1979 Drs Jeffrey Eckardt Kevin Ehrhart Jack Purdy Henry Tanz Bruce Watanabe Class of 1978 Drs Maximo Matos William Parker Thomas Pojunas Allen Richardson Norman Sprague III George Thompson Class of 1977 Drs Hans Anderson Marc Friedman Larry Herron Kenton Horacek John Moreland Class of 1976 Drs Richard Bergsrud Paul Feldon Richard Marafioti Michael Newman Class of 1975 Drs Ronald Lamb Joseph Mensch Ronald Perelman Dennis Sakai Class of 1974 Drs Zaven Bilezikjian Robert Cassidy Lawrence Guinney Benjamin Lesin Class of 1973 Drs Warren Harding Robert Irving Class of 1972 Drs Michael Hirsch Kenneth Lay David Schurman Class of 1971 Drs Tom Darrah James Gray Class of 1970 Dr William Loscher Class of 1969 Drs Jerrold Goldman Mark Wellisch Class of 1968 Drs David Culton Mark Hamerling Class of 1967 Drs Thomas Christianson John F Lawrence Class of 1964 Dr Syemour Gassner Class of 1961 Dr Bruce Robinson Class of 1960 Drs William Mullally Robert Watanabe Class of 1958 Dr Robert Horne

ALUMNI UPDATE

The UCSF Sports Medicine Fellowship is led by Program Director and alumnus Brian Feeley MD Class of 2007

29

A Message from former Alumni Director Seth C Gamradt MD

It has been my pleasure to serve as UCLA Orthopaedic Surgeryrsquos first Alumni Director and it is bittersweet leaving this outstanding Department I first came to the Department in 1999 as a fourth year medical student sub-intern from Cornell University Medical College During residency I took advantage of all the program has to offer including outstanding surgical and clinical training as well as the opportunity to spend a year focused on orthopaedic research I would like to thank the entire faculty of the Department who provided outstanding mentorship to me as a resident and accepted me as a colleague when I joined the Sports Medicine Faculty I owe particular thanks to Dr Gerald Finerman who hired me as Chief Resident and has placed tremendous trust in me over the years with the care of UCLA athletes In addition Dr Jeffrey Eckardt has served as a terrific role model for my approach to patient care and I appreciate his guidance and leadership Lastly I thank all of the current and former UCLA Orthopaedic Residents it is an honor to have participated in the education of this exceptional and dedicated group

Sincerely Seth C Gamradt MD Associate Clinical Professor of Orthopaedic Surgery Director of Orthopaedic Athletic Medicine for USC Athletics University of Southern California

Pictured above L-R Dr Richard Marafioti (rsquo76) Dr George Thompson (rsquo77) Mrs Thompson Dr Jeff Eckardt (rsquo79) Dr Tsou Dr Paul Tsou (Faculty) Pictured on right L-R Drs Mark Davies (rsquo03) Dan Oakes (rsquo03) Tony Scaduto (rsquo02) Seth Gamradt (rsquo06) Jason Zemanovic (rsquo03) and Brian Feeley (rsquo07)

Pictures from the AAOS UCLAOH Department of

Orthopaedic Surgery Alumni Reception February 10 2012 San Francisco CA

30

Pictured above L-RDr Richard Marafioti (rsquo76) Dr George Thompson (rsquo77) Mrs Thompson Dr Jeff Eckardt (rsquo79) Dr Tsou Dr Paul Tsou (Faculty) Pictured on right L-R Drs Mark Davies (rsquo03) Dan Oakes (rsquo03) Tony Scaduto (rsquo02) Seth Gamradt (rsquo06) Jason Zemanovic (rsquo03) and Brian Feeley (rsquo07)

Donors to the Orthopaedic Department Resident Education

Alumni Faculty Friends (Since July 2010)

Residents Norman Sprague MD Class of 1978 Jeffrey Eckardt MD Class of 1979Faculty Gregory Koski MD Class of 1984 Tye Ouzounian MD Class of 1987 Andre Gazdag MD Class of 1997 David Boardman MD Class of 1998 Stephen Timon MD Class of 2002 Mark Davies MD Class of 2003 Dan Oakes MD Class of 2003 Brian Feeley MD Class of 2007 Faculty and Friends Gerald Finerman MD Faculty Margot and Thomas Barron Friends Joaquin Fuster MD Friend Walter Jennings MD Friend Theo and Wendy Kolokotrones Friends William Swanson MD Friend

TAX-DEDUCTIBLE DONATIONS By Mail or In Person Please see Pledge Form inside bulletin and make checks payable to The UCLA Foundation Online wwwgivinguclaeduorthopaedicsurgery Contact Kathleen Lago Director UCLA Health Sciences Development (310) 206-3079 klagosupportuclaedu

IN MEMORIAM

Residents

Robert Watanabe MD (1992) Class of 1960

Edgar Dawson MD (2003)

Class of 1971

Ronald Lamb MD Class of 1975

Allen Richardson MD (2003)

Class of 1978

Roderick Smith MD (1977) Class of 1979

Jan Stehlik MD

Class of 1981

David Fisher MD Class of 1988

Sean OrsquoBrien MD (1988)

Class of 1989

Faculty

Charles Bechtol MD (1998) Founding Division Chief 1957-1970

UCLA Orthopaedic Surgery Faculty 1957-1970

Edgar Dawson MD (2003) Founder Orthopaedic Spine Program 1972

UCLA Orthopaedic Surgery Faculty 1972-2003 Class of 1971

Todd Grant MD (1996)

Founder Orthopaedic Oncology Program 1975 UCLA Orthopaedic Surgery Faculty 1973-1978

26

2 Comparison of Multi-lineage Cells from Human Adipose and Bone Marrow Cells Tissue and Organs 2003 174101-9

3 Dragoo JL Samimi B Zhu M Hame SL Thomas BJ Lieberman JR Hedrick MH Benhaim P Tissue-Engineered Cartilage and Bone Using Stem Cells From Human Infrapatellar Fat Pads JBJS 2003 85-B740-7

4 Lieberman JR Thomas BJ Finerman GA Dorey F Patientsrsquo Reasons for Undergoing Total Hip Arthroplasty Can Change Over Time J Arthroplasty 2003 Jan 18(1) 63-68

5 Clark CR Huddleston HD Schoch EP and Thomas BJ Leg-Length Discrepancy After Total Hip Arthroplasty JAAOS 2006 14 38 ndash 45

Daniel Vigil MD

1 Vigil DV Heat Illness in Twenty Common Problems in Sports Medicine Puffer JC editor 1st ed New York NY McGraw-Hill 2001 303-21

2 Vigil DV Soccer in Sports Injuries amp Emergencies Rubin AL editor 1st ed New York NY McGraw-Hill 2003 355-61

3 Shah S Vigil DV Luftman JL Stress injury of the talar dome and body in a ballerina a case report J Dance Med Sci 2005 9(3amp4)91-5

4 Ong AL Vigil DV What to do with a heart murmur and hypertension found during a preparticipation physical evaluation Perm Med J Fall 2005 9(4) 20-22

5 Peng HP Vigil DV Ankle Injury ndash Gymnastics Med Sci Sports Exerc 2011 (43)5 Supplement

Jeffrey Wang MD 1 Jeffrey C Wang MD Stephen Yoo BA Linda EA

Kanim MA Patricia A CampbellPhD Arnold Berk MD Jay R Lieberman MD Effect of Regional Gene Therapy with Bone Morphogenetic Protein -2-producing Bone Marrow Cells on Spinal Fusion in Rats The Journal of Bone and Joint Surgery 2003 Vol 85A(5)905-911

2 Miyazaki M Sugiyama O Tow B Zou J Morishita Y Wei F Napoli A Sintuu C Lieberman JR Wang JC The effects of lentiviral gene therapy with bone morphogenetic protein-2-producing bone marrow cells on spinal fusion in rats J Spinal Disord Tech 2008 Jul21(5)372-9

3 Lee KB Murray SS Duarte ME Spitz JF Johnson JS Song KJ Brochmann EJ Taghavi CE Keorochana G Liao JC Wang JC Effects of the bone morphogenetic protein binding protein spp24 (secreted phosphoprotein 24thinspkD) on the growth of human lung cancer cells J Orthop Res 2011 Apr 20 doi 101002jor21383 [Epub ahead of print]

4 Sintuu C Simon RJ Miyazaki M Morishita Y Hymanson HJ Taghavi C Brochmann EJ Murray SS Wang JC Full-Length spp24 but Not Its 185-kDa Proteolytic Fragment Inhibits Bone-Healing in a Rodent Model of Spine Fusion J Bone Joint Surg Am 2011 Jun 193(11)1022-32

5 Lee KB Murray SS Taghavi CE Song KJ Brochmann EJ Johnson JS Keorochana G Liao JC Wang JC Bone morphogenetic proteinndashbinding peptide reduces the inflammatory response to recombinant human bone morphogenetic protein-2 and recombinant human bone morphogenetic protein-7 in a rodent model of soft-tissue inflammation The Spine Journal 11 (2011) 568ndash576

Lewis Zionts MD

1 Zionts LE Zhao G Hitchcock K Maewal J Ebramzadeh E Has the rate of extensive surgery to treat idiopathic clubfoot declined in the United States J Bone Joint Surg Am 201092882-889

2 Zionts LE Dietz FC Post-corrective bracing in the treatment of idiopathic clubfeet using the Ponseti method J Am Acad Orthop Surg 201018486-493

3 Zionts LE Morcuende JA Ebramzadeh E Sangiorgio SN The current management of idiopathic clubfoot revisited Results of a survey of the POSNA membership J Pediatr Orthop 201232515ndash520

4 Zionts LE Frost N Kim R Ebramzadeh E Sangiorgio SN Treatment of idiopathic clubfoot Experience with the Mitchell-Ponseti brace J Pediatr Orthop 201232706-713

5 Silva M Eagan MJ Wong MA Dichter DH Ebramzadeh E Zionts LE Early weight-bearing in the closed treatment of tibial shaft fractures in children J Bone Joint Surg Am 2012941853-1860

27

Alumni Class of 2011 Drs Joshua Bales Brent Berger Adam Bier Michael Eagan Lucie Krenek April Ligato Hillard (Theo) Spencer Class of 2010 Drs Chukwunenye Osuji Samuel Park Payam Moazzaz George Oji Eugene Farng Scott Crow Class of 2009 Drs Anna Cuomo Carlos Gonzalez Devon Jeffcoat Rajeev Pandarinath Frank Petrigliano Shail Vyas Class of 2008 Drs William Carroll III Dara Chafik Augustine Conduah Scott Mitchell Miguel Sandoval Charles Young Class of 2007 Drs Kimberley Caputo Brian Feeley Jason Freedman Wellington Hsu Yekaterina Karpitskaya Class of 2006 Drs Seth Gamradt Katherine Gray Eric Lin Eon Shin Samir Tejiwani Yi-Meng Yen Class of 2005 Drs Kent Jackson Craig Kuhns Brett Peterson Jonathan Roper Stephen Struble Peter Whang Class of 2004 Drs Ethan Alpern Elliot Carlisle Jason Dragoo Yu-Po Lee Rod Payman Brian Rudin Class of 2003 Drs Nitin Bhatia Mark Davies Gary Ghiselli Daniel Oakes Ben Pradhan Jason Zemanovic Class of 2002 Drs Travis Hanson Tze Ip Stephen Nuccion Anthony Scaduto Michael Shepard Stephen Timon Class of 2001 Drs Richard Bowen Matthew Geck Kambiz Hannani John Nassar Edward Sun Erik Zeegen Class of 2000 Drs Janet Baker Aaron Daluiski Brent Davis Mohammed Etminan Paul McDonough Manish Patel

Class of 1999 Drs Hugh Bassewitz Joshua Hatch David Rogers Roger Sun James Ushiba Warren Yu Class of 1998 Drs Kevin Armstrong David Boardman Ward Hamlet Gregory Horner Scott Rosenzweig Scott Smith Class of 1997 Drs Andre Gazdag Mark Henry Michiyuki Kono Edward (Ted) Riley Jr Benjamin Tamm Gary Zohman

Class of 1996 Drs Eric Freedman Robert Kay Vivek Kushwaha Julie Melchior J Scott Smith Jeffrey Wang Class of 1995 Drs Douglas Freedman Thomas Gautsch David Hak Robert Henshaw William Jason David Lamey Philip Wirganowicz Class of 1994 Drs Bruce Bragonier Gregory Chow Craig Davis Karen Johnston-Jones Jeffrey Spychalski Michael Wall Class of 1993 Drs David Hillsgrove James Lubowitz William Luetzow Joe Minchew Alan Moelleken Edward (Ted) Parks Marc Safran Class of 1992 Drs Areesak Chotivichit Emil Dionysian James Gebhard Raymond Severt Peter Romano Tom Thomas Class of 1991 Drs Gregory Duncan Tadashi (Ted) Funahashi Kurt Larson Robert Namba James Nugent William Pfeiffer Lawrence Shin Class of 1990 Drs Avi Bernstein Michael Kody Yu Fon Lee James Leipzig Thomas Schmalzried Class of 1989 Drs David Friscia David Mesna Robert More David Thordarson Class of 1988 Drs David Fisher David Grauer George Lian Stephen Timothy Mar Shoemaker John Skubic Class of 1987 Drs Donald Hales Richard Kahmann Daniel Kaplan Paul Nottingham Tye Ouzounian Robert Wilson Class of 1986 Drs Robert Audell Brian Carney Rick Delamarter Richard Feldman Thomas Grogan Gregory Hanker Riyaz Jinnah Class of 1985 Drs J Randall Davis Steven Ma Richard Marder Steven Schopler Steven Silbart Class of 1984 Drs Michael Bayer Scott Graham Gregory Koski Kirk Lewis Edward Littlejohn Bert Thomas Class of 1983 Drs Lesley Anderson Wayne Christie Timothy Clader Steven Gausewitz Leslie Kim John Rollins Class of 1982 Drs Allan Delman Richard Ferkel Humberto Galleno Frederic Nicola Thomas Roberts

28

ALUMNI UPDATE

The Kaiser Orange County Sports Medicine Fellowship is led by Program Director and residency alumnus Brent Davis MD (below left) Class of 2000 with assistance by sports faculty member and residency alumnus Ted Funahashi MD (below right) Class of 1991 who is also a recent AOA inductee

Class of 1981 Drs Kenneth Baldwin Mark Bernstein David Cherney Roland Dutton Eric Johnson Jan Stehlik Class of 1980 Drs David Bowes Lynn Cooman Adrian Graff-Radford Matthew Lotysch Andrew Shaffer Class of 1979 Drs Jeffrey Eckardt Kevin Ehrhart Jack Purdy Henry Tanz Bruce Watanabe Class of 1978 Drs Maximo Matos William Parker Thomas Pojunas Allen Richardson Norman Sprague III George Thompson Class of 1977 Drs Hans Anderson Marc Friedman Larry Herron Kenton Horacek John Moreland Class of 1976 Drs Richard Bergsrud Paul Feldon Richard Marafioti Michael Newman Class of 1975 Drs Ronald Lamb Joseph Mensch Ronald Perelman Dennis Sakai Class of 1974 Drs Zaven Bilezikjian Robert Cassidy Lawrence Guinney Benjamin Lesin Class of 1973 Drs Warren Harding Robert Irving Class of 1972 Drs Michael Hirsch Kenneth Lay David Schurman Class of 1971 Drs Tom Darrah James Gray Class of 1970 Dr William Loscher Class of 1969 Drs Jerrold Goldman Mark Wellisch Class of 1968 Drs David Culton Mark Hamerling Class of 1967 Drs Thomas Christianson John F Lawrence Class of 1964 Dr Syemour Gassner Class of 1961 Dr Bruce Robinson Class of 1960 Drs William Mullally Robert Watanabe Class of 1958 Dr Robert Horne

ALUMNI UPDATE

The UCSF Sports Medicine Fellowship is led by Program Director and alumnus Brian Feeley MD Class of 2007

29

A Message from former Alumni Director Seth C Gamradt MD

It has been my pleasure to serve as UCLA Orthopaedic Surgeryrsquos first Alumni Director and it is bittersweet leaving this outstanding Department I first came to the Department in 1999 as a fourth year medical student sub-intern from Cornell University Medical College During residency I took advantage of all the program has to offer including outstanding surgical and clinical training as well as the opportunity to spend a year focused on orthopaedic research I would like to thank the entire faculty of the Department who provided outstanding mentorship to me as a resident and accepted me as a colleague when I joined the Sports Medicine Faculty I owe particular thanks to Dr Gerald Finerman who hired me as Chief Resident and has placed tremendous trust in me over the years with the care of UCLA athletes In addition Dr Jeffrey Eckardt has served as a terrific role model for my approach to patient care and I appreciate his guidance and leadership Lastly I thank all of the current and former UCLA Orthopaedic Residents it is an honor to have participated in the education of this exceptional and dedicated group

Sincerely Seth C Gamradt MD Associate Clinical Professor of Orthopaedic Surgery Director of Orthopaedic Athletic Medicine for USC Athletics University of Southern California

Pictured above L-R Dr Richard Marafioti (rsquo76) Dr George Thompson (rsquo77) Mrs Thompson Dr Jeff Eckardt (rsquo79) Dr Tsou Dr Paul Tsou (Faculty) Pictured on right L-R Drs Mark Davies (rsquo03) Dan Oakes (rsquo03) Tony Scaduto (rsquo02) Seth Gamradt (rsquo06) Jason Zemanovic (rsquo03) and Brian Feeley (rsquo07)

Pictures from the AAOS UCLAOH Department of

Orthopaedic Surgery Alumni Reception February 10 2012 San Francisco CA

30

Pictured above L-RDr Richard Marafioti (rsquo76) Dr George Thompson (rsquo77) Mrs Thompson Dr Jeff Eckardt (rsquo79) Dr Tsou Dr Paul Tsou (Faculty) Pictured on right L-R Drs Mark Davies (rsquo03) Dan Oakes (rsquo03) Tony Scaduto (rsquo02) Seth Gamradt (rsquo06) Jason Zemanovic (rsquo03) and Brian Feeley (rsquo07)

Donors to the Orthopaedic Department Resident Education

Alumni Faculty Friends (Since July 2010)

Residents Norman Sprague MD Class of 1978 Jeffrey Eckardt MD Class of 1979Faculty Gregory Koski MD Class of 1984 Tye Ouzounian MD Class of 1987 Andre Gazdag MD Class of 1997 David Boardman MD Class of 1998 Stephen Timon MD Class of 2002 Mark Davies MD Class of 2003 Dan Oakes MD Class of 2003 Brian Feeley MD Class of 2007 Faculty and Friends Gerald Finerman MD Faculty Margot and Thomas Barron Friends Joaquin Fuster MD Friend Walter Jennings MD Friend Theo and Wendy Kolokotrones Friends William Swanson MD Friend

TAX-DEDUCTIBLE DONATIONS By Mail or In Person Please see Pledge Form inside bulletin and make checks payable to The UCLA Foundation Online wwwgivinguclaeduorthopaedicsurgery Contact Kathleen Lago Director UCLA Health Sciences Development (310) 206-3079 klagosupportuclaedu

IN MEMORIAM

Residents

Robert Watanabe MD (1992) Class of 1960

Edgar Dawson MD (2003)

Class of 1971

Ronald Lamb MD Class of 1975

Allen Richardson MD (2003)

Class of 1978

Roderick Smith MD (1977) Class of 1979

Jan Stehlik MD

Class of 1981

David Fisher MD Class of 1988

Sean OrsquoBrien MD (1988)

Class of 1989

Faculty

Charles Bechtol MD (1998) Founding Division Chief 1957-1970

UCLA Orthopaedic Surgery Faculty 1957-1970

Edgar Dawson MD (2003) Founder Orthopaedic Spine Program 1972

UCLA Orthopaedic Surgery Faculty 1972-2003 Class of 1971

Todd Grant MD (1996)

Founder Orthopaedic Oncology Program 1975 UCLA Orthopaedic Surgery Faculty 1973-1978

27

Alumni Class of 2011 Drs Joshua Bales Brent Berger Adam Bier Michael Eagan Lucie Krenek April Ligato Hillard (Theo) Spencer Class of 2010 Drs Chukwunenye Osuji Samuel Park Payam Moazzaz George Oji Eugene Farng Scott Crow Class of 2009 Drs Anna Cuomo Carlos Gonzalez Devon Jeffcoat Rajeev Pandarinath Frank Petrigliano Shail Vyas Class of 2008 Drs William Carroll III Dara Chafik Augustine Conduah Scott Mitchell Miguel Sandoval Charles Young Class of 2007 Drs Kimberley Caputo Brian Feeley Jason Freedman Wellington Hsu Yekaterina Karpitskaya Class of 2006 Drs Seth Gamradt Katherine Gray Eric Lin Eon Shin Samir Tejiwani Yi-Meng Yen Class of 2005 Drs Kent Jackson Craig Kuhns Brett Peterson Jonathan Roper Stephen Struble Peter Whang Class of 2004 Drs Ethan Alpern Elliot Carlisle Jason Dragoo Yu-Po Lee Rod Payman Brian Rudin Class of 2003 Drs Nitin Bhatia Mark Davies Gary Ghiselli Daniel Oakes Ben Pradhan Jason Zemanovic Class of 2002 Drs Travis Hanson Tze Ip Stephen Nuccion Anthony Scaduto Michael Shepard Stephen Timon Class of 2001 Drs Richard Bowen Matthew Geck Kambiz Hannani John Nassar Edward Sun Erik Zeegen Class of 2000 Drs Janet Baker Aaron Daluiski Brent Davis Mohammed Etminan Paul McDonough Manish Patel

Class of 1999 Drs Hugh Bassewitz Joshua Hatch David Rogers Roger Sun James Ushiba Warren Yu Class of 1998 Drs Kevin Armstrong David Boardman Ward Hamlet Gregory Horner Scott Rosenzweig Scott Smith Class of 1997 Drs Andre Gazdag Mark Henry Michiyuki Kono Edward (Ted) Riley Jr Benjamin Tamm Gary Zohman

Class of 1996 Drs Eric Freedman Robert Kay Vivek Kushwaha Julie Melchior J Scott Smith Jeffrey Wang Class of 1995 Drs Douglas Freedman Thomas Gautsch David Hak Robert Henshaw William Jason David Lamey Philip Wirganowicz Class of 1994 Drs Bruce Bragonier Gregory Chow Craig Davis Karen Johnston-Jones Jeffrey Spychalski Michael Wall Class of 1993 Drs David Hillsgrove James Lubowitz William Luetzow Joe Minchew Alan Moelleken Edward (Ted) Parks Marc Safran Class of 1992 Drs Areesak Chotivichit Emil Dionysian James Gebhard Raymond Severt Peter Romano Tom Thomas Class of 1991 Drs Gregory Duncan Tadashi (Ted) Funahashi Kurt Larson Robert Namba James Nugent William Pfeiffer Lawrence Shin Class of 1990 Drs Avi Bernstein Michael Kody Yu Fon Lee James Leipzig Thomas Schmalzried Class of 1989 Drs David Friscia David Mesna Robert More David Thordarson Class of 1988 Drs David Fisher David Grauer George Lian Stephen Timothy Mar Shoemaker John Skubic Class of 1987 Drs Donald Hales Richard Kahmann Daniel Kaplan Paul Nottingham Tye Ouzounian Robert Wilson Class of 1986 Drs Robert Audell Brian Carney Rick Delamarter Richard Feldman Thomas Grogan Gregory Hanker Riyaz Jinnah Class of 1985 Drs J Randall Davis Steven Ma Richard Marder Steven Schopler Steven Silbart Class of 1984 Drs Michael Bayer Scott Graham Gregory Koski Kirk Lewis Edward Littlejohn Bert Thomas Class of 1983 Drs Lesley Anderson Wayne Christie Timothy Clader Steven Gausewitz Leslie Kim John Rollins Class of 1982 Drs Allan Delman Richard Ferkel Humberto Galleno Frederic Nicola Thomas Roberts

28

ALUMNI UPDATE

The Kaiser Orange County Sports Medicine Fellowship is led by Program Director and residency alumnus Brent Davis MD (below left) Class of 2000 with assistance by sports faculty member and residency alumnus Ted Funahashi MD (below right) Class of 1991 who is also a recent AOA inductee

Class of 1981 Drs Kenneth Baldwin Mark Bernstein David Cherney Roland Dutton Eric Johnson Jan Stehlik Class of 1980 Drs David Bowes Lynn Cooman Adrian Graff-Radford Matthew Lotysch Andrew Shaffer Class of 1979 Drs Jeffrey Eckardt Kevin Ehrhart Jack Purdy Henry Tanz Bruce Watanabe Class of 1978 Drs Maximo Matos William Parker Thomas Pojunas Allen Richardson Norman Sprague III George Thompson Class of 1977 Drs Hans Anderson Marc Friedman Larry Herron Kenton Horacek John Moreland Class of 1976 Drs Richard Bergsrud Paul Feldon Richard Marafioti Michael Newman Class of 1975 Drs Ronald Lamb Joseph Mensch Ronald Perelman Dennis Sakai Class of 1974 Drs Zaven Bilezikjian Robert Cassidy Lawrence Guinney Benjamin Lesin Class of 1973 Drs Warren Harding Robert Irving Class of 1972 Drs Michael Hirsch Kenneth Lay David Schurman Class of 1971 Drs Tom Darrah James Gray Class of 1970 Dr William Loscher Class of 1969 Drs Jerrold Goldman Mark Wellisch Class of 1968 Drs David Culton Mark Hamerling Class of 1967 Drs Thomas Christianson John F Lawrence Class of 1964 Dr Syemour Gassner Class of 1961 Dr Bruce Robinson Class of 1960 Drs William Mullally Robert Watanabe Class of 1958 Dr Robert Horne

ALUMNI UPDATE

The UCSF Sports Medicine Fellowship is led by Program Director and alumnus Brian Feeley MD Class of 2007

29

A Message from former Alumni Director Seth C Gamradt MD

It has been my pleasure to serve as UCLA Orthopaedic Surgeryrsquos first Alumni Director and it is bittersweet leaving this outstanding Department I first came to the Department in 1999 as a fourth year medical student sub-intern from Cornell University Medical College During residency I took advantage of all the program has to offer including outstanding surgical and clinical training as well as the opportunity to spend a year focused on orthopaedic research I would like to thank the entire faculty of the Department who provided outstanding mentorship to me as a resident and accepted me as a colleague when I joined the Sports Medicine Faculty I owe particular thanks to Dr Gerald Finerman who hired me as Chief Resident and has placed tremendous trust in me over the years with the care of UCLA athletes In addition Dr Jeffrey Eckardt has served as a terrific role model for my approach to patient care and I appreciate his guidance and leadership Lastly I thank all of the current and former UCLA Orthopaedic Residents it is an honor to have participated in the education of this exceptional and dedicated group

Sincerely Seth C Gamradt MD Associate Clinical Professor of Orthopaedic Surgery Director of Orthopaedic Athletic Medicine for USC Athletics University of Southern California

Pictured above L-R Dr Richard Marafioti (rsquo76) Dr George Thompson (rsquo77) Mrs Thompson Dr Jeff Eckardt (rsquo79) Dr Tsou Dr Paul Tsou (Faculty) Pictured on right L-R Drs Mark Davies (rsquo03) Dan Oakes (rsquo03) Tony Scaduto (rsquo02) Seth Gamradt (rsquo06) Jason Zemanovic (rsquo03) and Brian Feeley (rsquo07)

Pictures from the AAOS UCLAOH Department of

Orthopaedic Surgery Alumni Reception February 10 2012 San Francisco CA

30

Pictured above L-RDr Richard Marafioti (rsquo76) Dr George Thompson (rsquo77) Mrs Thompson Dr Jeff Eckardt (rsquo79) Dr Tsou Dr Paul Tsou (Faculty) Pictured on right L-R Drs Mark Davies (rsquo03) Dan Oakes (rsquo03) Tony Scaduto (rsquo02) Seth Gamradt (rsquo06) Jason Zemanovic (rsquo03) and Brian Feeley (rsquo07)

Donors to the Orthopaedic Department Resident Education

Alumni Faculty Friends (Since July 2010)

Residents Norman Sprague MD Class of 1978 Jeffrey Eckardt MD Class of 1979Faculty Gregory Koski MD Class of 1984 Tye Ouzounian MD Class of 1987 Andre Gazdag MD Class of 1997 David Boardman MD Class of 1998 Stephen Timon MD Class of 2002 Mark Davies MD Class of 2003 Dan Oakes MD Class of 2003 Brian Feeley MD Class of 2007 Faculty and Friends Gerald Finerman MD Faculty Margot and Thomas Barron Friends Joaquin Fuster MD Friend Walter Jennings MD Friend Theo and Wendy Kolokotrones Friends William Swanson MD Friend

TAX-DEDUCTIBLE DONATIONS By Mail or In Person Please see Pledge Form inside bulletin and make checks payable to The UCLA Foundation Online wwwgivinguclaeduorthopaedicsurgery Contact Kathleen Lago Director UCLA Health Sciences Development (310) 206-3079 klagosupportuclaedu

IN MEMORIAM

Residents

Robert Watanabe MD (1992) Class of 1960

Edgar Dawson MD (2003)

Class of 1971

Ronald Lamb MD Class of 1975

Allen Richardson MD (2003)

Class of 1978

Roderick Smith MD (1977) Class of 1979

Jan Stehlik MD

Class of 1981

David Fisher MD Class of 1988

Sean OrsquoBrien MD (1988)

Class of 1989

Faculty

Charles Bechtol MD (1998) Founding Division Chief 1957-1970

UCLA Orthopaedic Surgery Faculty 1957-1970

Edgar Dawson MD (2003) Founder Orthopaedic Spine Program 1972

UCLA Orthopaedic Surgery Faculty 1972-2003 Class of 1971

Todd Grant MD (1996)

Founder Orthopaedic Oncology Program 1975 UCLA Orthopaedic Surgery Faculty 1973-1978

28

ALUMNI UPDATE

The Kaiser Orange County Sports Medicine Fellowship is led by Program Director and residency alumnus Brent Davis MD (below left) Class of 2000 with assistance by sports faculty member and residency alumnus Ted Funahashi MD (below right) Class of 1991 who is also a recent AOA inductee

Class of 1981 Drs Kenneth Baldwin Mark Bernstein David Cherney Roland Dutton Eric Johnson Jan Stehlik Class of 1980 Drs David Bowes Lynn Cooman Adrian Graff-Radford Matthew Lotysch Andrew Shaffer Class of 1979 Drs Jeffrey Eckardt Kevin Ehrhart Jack Purdy Henry Tanz Bruce Watanabe Class of 1978 Drs Maximo Matos William Parker Thomas Pojunas Allen Richardson Norman Sprague III George Thompson Class of 1977 Drs Hans Anderson Marc Friedman Larry Herron Kenton Horacek John Moreland Class of 1976 Drs Richard Bergsrud Paul Feldon Richard Marafioti Michael Newman Class of 1975 Drs Ronald Lamb Joseph Mensch Ronald Perelman Dennis Sakai Class of 1974 Drs Zaven Bilezikjian Robert Cassidy Lawrence Guinney Benjamin Lesin Class of 1973 Drs Warren Harding Robert Irving Class of 1972 Drs Michael Hirsch Kenneth Lay David Schurman Class of 1971 Drs Tom Darrah James Gray Class of 1970 Dr William Loscher Class of 1969 Drs Jerrold Goldman Mark Wellisch Class of 1968 Drs David Culton Mark Hamerling Class of 1967 Drs Thomas Christianson John F Lawrence Class of 1964 Dr Syemour Gassner Class of 1961 Dr Bruce Robinson Class of 1960 Drs William Mullally Robert Watanabe Class of 1958 Dr Robert Horne

ALUMNI UPDATE

The UCSF Sports Medicine Fellowship is led by Program Director and alumnus Brian Feeley MD Class of 2007

29

A Message from former Alumni Director Seth C Gamradt MD

It has been my pleasure to serve as UCLA Orthopaedic Surgeryrsquos first Alumni Director and it is bittersweet leaving this outstanding Department I first came to the Department in 1999 as a fourth year medical student sub-intern from Cornell University Medical College During residency I took advantage of all the program has to offer including outstanding surgical and clinical training as well as the opportunity to spend a year focused on orthopaedic research I would like to thank the entire faculty of the Department who provided outstanding mentorship to me as a resident and accepted me as a colleague when I joined the Sports Medicine Faculty I owe particular thanks to Dr Gerald Finerman who hired me as Chief Resident and has placed tremendous trust in me over the years with the care of UCLA athletes In addition Dr Jeffrey Eckardt has served as a terrific role model for my approach to patient care and I appreciate his guidance and leadership Lastly I thank all of the current and former UCLA Orthopaedic Residents it is an honor to have participated in the education of this exceptional and dedicated group

Sincerely Seth C Gamradt MD Associate Clinical Professor of Orthopaedic Surgery Director of Orthopaedic Athletic Medicine for USC Athletics University of Southern California

Pictured above L-R Dr Richard Marafioti (rsquo76) Dr George Thompson (rsquo77) Mrs Thompson Dr Jeff Eckardt (rsquo79) Dr Tsou Dr Paul Tsou (Faculty) Pictured on right L-R Drs Mark Davies (rsquo03) Dan Oakes (rsquo03) Tony Scaduto (rsquo02) Seth Gamradt (rsquo06) Jason Zemanovic (rsquo03) and Brian Feeley (rsquo07)

Pictures from the AAOS UCLAOH Department of

Orthopaedic Surgery Alumni Reception February 10 2012 San Francisco CA

30

Pictured above L-RDr Richard Marafioti (rsquo76) Dr George Thompson (rsquo77) Mrs Thompson Dr Jeff Eckardt (rsquo79) Dr Tsou Dr Paul Tsou (Faculty) Pictured on right L-R Drs Mark Davies (rsquo03) Dan Oakes (rsquo03) Tony Scaduto (rsquo02) Seth Gamradt (rsquo06) Jason Zemanovic (rsquo03) and Brian Feeley (rsquo07)

Donors to the Orthopaedic Department Resident Education

Alumni Faculty Friends (Since July 2010)

Residents Norman Sprague MD Class of 1978 Jeffrey Eckardt MD Class of 1979Faculty Gregory Koski MD Class of 1984 Tye Ouzounian MD Class of 1987 Andre Gazdag MD Class of 1997 David Boardman MD Class of 1998 Stephen Timon MD Class of 2002 Mark Davies MD Class of 2003 Dan Oakes MD Class of 2003 Brian Feeley MD Class of 2007 Faculty and Friends Gerald Finerman MD Faculty Margot and Thomas Barron Friends Joaquin Fuster MD Friend Walter Jennings MD Friend Theo and Wendy Kolokotrones Friends William Swanson MD Friend

TAX-DEDUCTIBLE DONATIONS By Mail or In Person Please see Pledge Form inside bulletin and make checks payable to The UCLA Foundation Online wwwgivinguclaeduorthopaedicsurgery Contact Kathleen Lago Director UCLA Health Sciences Development (310) 206-3079 klagosupportuclaedu

IN MEMORIAM

Residents

Robert Watanabe MD (1992) Class of 1960

Edgar Dawson MD (2003)

Class of 1971

Ronald Lamb MD Class of 1975

Allen Richardson MD (2003)

Class of 1978

Roderick Smith MD (1977) Class of 1979

Jan Stehlik MD

Class of 1981

David Fisher MD Class of 1988

Sean OrsquoBrien MD (1988)

Class of 1989

Faculty

Charles Bechtol MD (1998) Founding Division Chief 1957-1970

UCLA Orthopaedic Surgery Faculty 1957-1970

Edgar Dawson MD (2003) Founder Orthopaedic Spine Program 1972

UCLA Orthopaedic Surgery Faculty 1972-2003 Class of 1971

Todd Grant MD (1996)

Founder Orthopaedic Oncology Program 1975 UCLA Orthopaedic Surgery Faculty 1973-1978

29

A Message from former Alumni Director Seth C Gamradt MD

It has been my pleasure to serve as UCLA Orthopaedic Surgeryrsquos first Alumni Director and it is bittersweet leaving this outstanding Department I first came to the Department in 1999 as a fourth year medical student sub-intern from Cornell University Medical College During residency I took advantage of all the program has to offer including outstanding surgical and clinical training as well as the opportunity to spend a year focused on orthopaedic research I would like to thank the entire faculty of the Department who provided outstanding mentorship to me as a resident and accepted me as a colleague when I joined the Sports Medicine Faculty I owe particular thanks to Dr Gerald Finerman who hired me as Chief Resident and has placed tremendous trust in me over the years with the care of UCLA athletes In addition Dr Jeffrey Eckardt has served as a terrific role model for my approach to patient care and I appreciate his guidance and leadership Lastly I thank all of the current and former UCLA Orthopaedic Residents it is an honor to have participated in the education of this exceptional and dedicated group

Sincerely Seth C Gamradt MD Associate Clinical Professor of Orthopaedic Surgery Director of Orthopaedic Athletic Medicine for USC Athletics University of Southern California

Pictured above L-R Dr Richard Marafioti (rsquo76) Dr George Thompson (rsquo77) Mrs Thompson Dr Jeff Eckardt (rsquo79) Dr Tsou Dr Paul Tsou (Faculty) Pictured on right L-R Drs Mark Davies (rsquo03) Dan Oakes (rsquo03) Tony Scaduto (rsquo02) Seth Gamradt (rsquo06) Jason Zemanovic (rsquo03) and Brian Feeley (rsquo07)

Pictures from the AAOS UCLAOH Department of

Orthopaedic Surgery Alumni Reception February 10 2012 San Francisco CA

30

Pictured above L-RDr Richard Marafioti (rsquo76) Dr George Thompson (rsquo77) Mrs Thompson Dr Jeff Eckardt (rsquo79) Dr Tsou Dr Paul Tsou (Faculty) Pictured on right L-R Drs Mark Davies (rsquo03) Dan Oakes (rsquo03) Tony Scaduto (rsquo02) Seth Gamradt (rsquo06) Jason Zemanovic (rsquo03) and Brian Feeley (rsquo07)

Donors to the Orthopaedic Department Resident Education

Alumni Faculty Friends (Since July 2010)

Residents Norman Sprague MD Class of 1978 Jeffrey Eckardt MD Class of 1979Faculty Gregory Koski MD Class of 1984 Tye Ouzounian MD Class of 1987 Andre Gazdag MD Class of 1997 David Boardman MD Class of 1998 Stephen Timon MD Class of 2002 Mark Davies MD Class of 2003 Dan Oakes MD Class of 2003 Brian Feeley MD Class of 2007 Faculty and Friends Gerald Finerman MD Faculty Margot and Thomas Barron Friends Joaquin Fuster MD Friend Walter Jennings MD Friend Theo and Wendy Kolokotrones Friends William Swanson MD Friend

TAX-DEDUCTIBLE DONATIONS By Mail or In Person Please see Pledge Form inside bulletin and make checks payable to The UCLA Foundation Online wwwgivinguclaeduorthopaedicsurgery Contact Kathleen Lago Director UCLA Health Sciences Development (310) 206-3079 klagosupportuclaedu

IN MEMORIAM

Residents

Robert Watanabe MD (1992) Class of 1960

Edgar Dawson MD (2003)

Class of 1971

Ronald Lamb MD Class of 1975

Allen Richardson MD (2003)

Class of 1978

Roderick Smith MD (1977) Class of 1979

Jan Stehlik MD

Class of 1981

David Fisher MD Class of 1988

Sean OrsquoBrien MD (1988)

Class of 1989

Faculty

Charles Bechtol MD (1998) Founding Division Chief 1957-1970

UCLA Orthopaedic Surgery Faculty 1957-1970

Edgar Dawson MD (2003) Founder Orthopaedic Spine Program 1972

UCLA Orthopaedic Surgery Faculty 1972-2003 Class of 1971

Todd Grant MD (1996)

Founder Orthopaedic Oncology Program 1975 UCLA Orthopaedic Surgery Faculty 1973-1978

30

Pictured above L-RDr Richard Marafioti (rsquo76) Dr George Thompson (rsquo77) Mrs Thompson Dr Jeff Eckardt (rsquo79) Dr Tsou Dr Paul Tsou (Faculty) Pictured on right L-R Drs Mark Davies (rsquo03) Dan Oakes (rsquo03) Tony Scaduto (rsquo02) Seth Gamradt (rsquo06) Jason Zemanovic (rsquo03) and Brian Feeley (rsquo07)

Donors to the Orthopaedic Department Resident Education

Alumni Faculty Friends (Since July 2010)

Residents Norman Sprague MD Class of 1978 Jeffrey Eckardt MD Class of 1979Faculty Gregory Koski MD Class of 1984 Tye Ouzounian MD Class of 1987 Andre Gazdag MD Class of 1997 David Boardman MD Class of 1998 Stephen Timon MD Class of 2002 Mark Davies MD Class of 2003 Dan Oakes MD Class of 2003 Brian Feeley MD Class of 2007 Faculty and Friends Gerald Finerman MD Faculty Margot and Thomas Barron Friends Joaquin Fuster MD Friend Walter Jennings MD Friend Theo and Wendy Kolokotrones Friends William Swanson MD Friend

TAX-DEDUCTIBLE DONATIONS By Mail or In Person Please see Pledge Form inside bulletin and make checks payable to The UCLA Foundation Online wwwgivinguclaeduorthopaedicsurgery Contact Kathleen Lago Director UCLA Health Sciences Development (310) 206-3079 klagosupportuclaedu

IN MEMORIAM

Residents

Robert Watanabe MD (1992) Class of 1960

Edgar Dawson MD (2003)

Class of 1971

Ronald Lamb MD Class of 1975

Allen Richardson MD (2003)

Class of 1978

Roderick Smith MD (1977) Class of 1979

Jan Stehlik MD

Class of 1981

David Fisher MD Class of 1988

Sean OrsquoBrien MD (1988)

Class of 1989

Faculty

Charles Bechtol MD (1998) Founding Division Chief 1957-1970

UCLA Orthopaedic Surgery Faculty 1957-1970

Edgar Dawson MD (2003) Founder Orthopaedic Spine Program 1972

UCLA Orthopaedic Surgery Faculty 1972-2003 Class of 1971

Todd Grant MD (1996)

Founder Orthopaedic Oncology Program 1975 UCLA Orthopaedic Surgery Faculty 1973-1978