TUTORIAL SBD2043 NOV 2012

1. Define core test, specialized test and emergency test. Give 2 examples of each.2. Discuss on how error could happen during sampling procedures.3. What are the pre-analytical errors that may affect the quality assurance in a lab?4. Explain factors that lead to hemolysis.5. Expect the abnormal reading of a hemolysed sample.6. Explain these enzyme reaction

a. Transferaseb. Hydrolasec. Ligase

7. Complete the table below:

Enzyme Origins

Bone tumour

Cardiac disease

Hepatic disease

8. Write the origin and cancers that associate with these tumor markers:a. Alpha Feto Proteinb. Human Chorionic Gonadotrophinec. Alkaline Phosphatased. Adrenocotricotrophine hormonee. Thyroid stimulating hormonef. Lactate dehydrogenaseg. Prostatic specific antigen

9. You are performing FEME test on cerebrospinal fluid sample. Write your findings if the specimen was sampled from these patients below.a. Viral meningitisb. Bacterial meningitisc. Tuberculous meningitisd. Fungal meningitis

10. Explain tests to investigate renal function.11. Write your finding of a test done on a urine sample taken from acute renal failure patient.12. What is the different between creatinine clearance and inulin clearance test?13. Explain the pathophysiology of PKU. 14. What is the symptom of maternal PKU to the baby? 15. Define hyperglycemia amd hypoglycaemia. What cause these conditions? 16. What are the complications of hyperlipidemia?17. What test should be asked from biochemistry lab to investigate below diseases:

a. Diabetes mellitusb. G6PD deficiencyc. Phenylketonuriad. Maple Syrup Urine disorder