Pathophysiology

ThrombophlebitisNarrowing of Vein

Platelet aggregation

Venous obstruction

Decrease Blood Flow

Venous wall abnormalityVenous StasisAbnormal

clotting

Inflammation

Edema

Movement of the thrombus within circulation

Lodging of thrombus in deep veins or superficial veins of lower extremities

Migration and lodging in pulmonary vasculature

Pulmonary embolism

Respiratory insufficiency

Ventilation /perfusion mismatching

Death