TheNational BIO-ECONOMY STRATEGY Dr Maneshree Jugmohan-Naidu D:
Biotechnology
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2 Content 1)Definition and Aims of the strategy 2)Timeline
3)Context 4)challenges/opportunities 5)Bio-economy Strategic
Objectives 6)Defining progress
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Bioeconomy Strategy 2013 "Bioeconomy" refers to activities that
make use of bio-innovations, based on biological sources, materials
and processes to generate sustainable economic, social and
environmental development.
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Aims of the Bio-economy Strategy: Provides an economic engine
for the new economy which will in turn provide a basis for future
growth. Science-based "biosolutions" can be used to, for instance
manufacture high-value protein products such as biopharmaceuticals
and vaccines; produce biofuels; improve and adapt crops; remedy
industrial and municipal waste; reduce production costs; reduce
environmental impacts; improve improve the global competitiveness
in the health, agriculture and industrial sector the quality of
products; improve the performance of a range of economic sectors. A
key objective is incorporating market pull into innovation
activities Allows SA to respond more directly to global challenges
such as the disease burden, food security, competitive industry,
climate change and energy requirements as well as to maximise local
beneficiation, improved quality of life and economic growth.
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Linked to other policies
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Timeline 6 Instruments: BRICs; NBN; PUB 2003 Merge into TIA
2009 2009 Outputs: 14 platforms established 73 projects funded
Investment into 31 companies 221 products & 142 services 940
jobs 439 bursaries/indirect study support R247 mill leveraged (on
R1 bill) Bio-economy Strategy development 2009-2013 Functioning NSI
2020 Bio- economy 5% of GDP 2050 Incorporation of learnings Nat
Biotech Strategy 2001
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Basic AppliedTech Develop Commercial Publications/new
knowledge/HCDPatents/new knowledge products Universities Science
Councils Industry Biotech Landscape Value Chain Performers Funding
Agencies Outputs NRF Service Platforms TIA/DSTIDC Centres of
Competence/Platforms CoE NIPMO SARChI Where to Next: Strategy to
strengthen the Bioeconomy.
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StrengthsWeaknesses Government commitment to The Bio-economy
through its policies/strategies and funding Mega biodiversity
Strong academic environment Excellent infrastructure Extensive
Indigenous Knowledge Stable political environment and growing
economy Emerging small companies Fragmented NSI - Researchers do
not work together to conceptualise bigger projects which take into
the value chain pipeline Innovation culture Public Awareness Water
scarce country Extended times for regulatory approval Lack of
skilled, qualified and experienced personnel Intellectual property
management Entrepreneurial culture at universities and public
research institutions underdeveloped Small biotechnology companies
are not self sustainable, relying on Government funding.
OpportunitiesThreats Private sector involvement in the
implementation of Government policies/strategies Private sector
willingness to train postgraduate students in Bio-entrepreneurship
International investment Emerging venture capitalists Other
Governments Departments willing to be involved in the development
of the Bio-economy Loss of skilled, qualified and experienced human
resources to othercountries Climate Change Aging skills SWOT
Analysis SA NSI
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9 o Portfolio Analysis Findings: o Investments at HEIs &
SCs: o Disruptive innovation. o Dont advance to market. o
Companies: o Incremental innovation o IP based companies succeed
vs. non-IP based. CONTEXT: Key features of SA Bio-economys NSI
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10 Challenges/opportunities Large but under-employed rural
communities High burden of disease, excellence in R&D, but
under- investment in innovation opportunities Increasing global
food quality standards Under-utilised but substantial - livestock
populations Need for continual improvement of commercially-relevant
plants & animals Need to revitalise certain labour-intensive
industries to maintain global competitiveness eg. sugar; forestry
Carbon footprint / green economy Commercialise& mainstream IKS
biodiversity products Climate Change
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11 Manage NSI according to industry sectors, and incorporate
value chain approach Three thematic chapters: Agriculture Health
Industry & Environment Bio-economy Approach
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Bio-economy: Agriculture Ensure food security, enhance
nutrition and improve health and enable job creation through
expansion and intensification of sustainable agricultural
production and processing. Strategic projects Crop/livestock
improvement both for biotic and physical stresses associated with
climate change (including indigenous crops) Agroprocessing
initiatives An integrated food nutrition research programme Animal
vaccine capabilities Energy-crop initiatives Biocontrol and
biofertilisers Aquaculture Soil conservation Water resource
management Build high-value skills and capacities to enable
agro-innovation Co-funding initiatives for innovation
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Bioeconomy: Health Sector Support and strengthen the country's
local RDI capabilities to manufacture APIs, vaccines,
biopharmaceuticals, diagnostics and medical devices to address the
disease burden while ensuring security of supply of essential
therapeutics and prophylactics. Strategic projects Develop improved
therapeutics and drug delivery systems to address priority diseases
including African Traditional Medicines Develop new and improved
vaccines and biologics Develop improved diagnostics Develop
improved medical devices Build clinical research and development
capabilities Establish pharmaceutical manufacturing
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Bio-economy: Industry and Environment Support research,
development and innovation in biological processes for the
production of goods and services, while enhancing water and
waste-management practices to support green economy. Strategic
projects Strategic industrial biotechnology programmes Strengthen
and develop bioprospecting capacity and capabilities Strengthen
local bioprocessing capabilities Develop integrated biorefineries
from bio-based feedstocks Strengthen wastewater research,
development and innovation Strengthen waste research, development
and innovation Synergies with enabling and emerging technologies.
Establish an advisory committee for industrial bio-economy
SERVICES REGULATION Skills & Human Capital Innovate
(Develop IP) Applied Research (Current Skills) BioDesign (Future
Skills) Commercialise (Exploit IP) Commercial products and services
INCUBATION (Facilities; business &marketing skills) INCUBATION
(Facilities; business &marketing skills) PILOT SCALE PRODUCTION
(bio-processing; bio-fermentation; bio-pharming) PILOT SCALE
PRODUCTION (bio-processing; bio-fermentation; bio-pharming)
TECHNOLOGY SERVICES (Genomics; Proteomics; Metabolomics;
Metagenomics; Bioinformatics; etc) TECHNOLOGY SERVICES (Genomics;
Proteomics; Metabolomics; Metagenomics; Bioinformatics; etc)
REGULATORY COMPLIANCE (BiosafetySA; clinical trialing; preclinical
platform) IP PROTECTION (NIPMO) IP PROTECTION (NIPMO)
BIO-REPOSITORY (Human;Animal; Plant; Microbes) BIO-REPOSITORY
(Human;Animal; Plant; Microbes) Research Ethics Human health
products (MCC); Food products (Codex); GMO products (GMO Act);
Biocontrol (Act 36) etc Biodiversity Regulations (access &
benefit sharing) Biodiversity Regulations (access & benefit
sharing) MTAs/ Genomic Sovereignty Coordinating Committees Industry
Government The Market
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Role of DST Key strategic objectives Coordinate stakeholders
and role players.- Promote active participation of ALL stakeholders
is key towards successful implementation, performance objectives
and milestones hence the coordination committees Coordination of
projects across value chain (networking of, & value-addition
to, projects) Orchestration of RDI innovators (incl. Technology
Platforms; Team SA) Alignment of RD&I with industry and govt.
needs Develop strategic innovation competencies. Development of the
full value chain from concept to product. Bioinformatics,
functional genomics, structural biology, synthetic biology and
systems biology. Technology service platforms. Pilot-scale
infrastructure. Incubation facilities. Financing. Human capital
development capital resources not just financially but also
multidisciplinary expertise Instruments to address specific
knowledge needs. Knowledge management to develop a bioportal..
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Role of DST Key strategic objectives, contd. Develop strategic
innovation programmes to address strategic gaps or opportunities
for the country Identify and drive RD&I in long-term programmes
which address National priorities HIV / AIDS [existing initiatives:
DST/MRC - SHIP; SHARP], TB [DST/MRC SHIP; SATRI] Ongoing
crop/animal improvement [ARC; TIA] Mainstreaming indigenous
products and agricultural goods [IKS; ARC; CSIR; TIA] Strengthening
Industry (revitalisation with alternative, competitive products
& processes based on biotechnologies) [Eucalyptus Forestry;
Sugarcane Industry; Waste treatment; Biocatalysis; TIA & CSIR]
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19 BioeconomyHCDR&DCommercial- isation Coordination
Bioeconomy contribution to GDP Student outputs per year No. of
publications and citations in high- impact journals per capita. No.
of products and services No. of collaborative research partnerships
Technology balance of payment of bio- innovation outputs.
Throughput of non- academic skills training (incl.
entrepreneurialism) Cumulative no. of bio- patents / plant breeders
rights No. of start up companies No of companies reaching break
even No. of collaborativeproduc t development partnerships No.of
bio-innovation firms, including dedicated bio- innovation firms by
sector Size of bio- workforce as percentage of S&T workforce.
No.of regulatory approvals for locally produced health/agricultural
products. No. multinational corporations in bio- economy sectors
locating R & D facilities locally No. of funding partnerships
No. of regulatory approvals for locally produced
health/agricultural products. Leveraging international resources
No. of projects progressing between funding institutions Indicators
(to be informed by study)