Looking forward The NLM Update

Tania Bardyn, MLS, AHIPAssociate Dean & Director

UW Health Sciences LibraryDirector, NN/LM, Pacific Northwest Region

PNC/MLA Annual Meeting

October 17, 2016

Patricia Flatley Brennan, RN, PhD sworn in as NLM Director, Sept. 12,2016

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https://videocast.nih.gov/summary.asp?Live=19671&bhcp=1

Source Text: titles of peer-reviewed articles in PF Brennan’s CV(3/2016)

Next NLM Strategic Plan-- development of planning process began Sept. 13/14, 2016 -- target completion date for plan: End of 2017-- 10-year horizon for vision; 5-year horizon for plan

NLM Board of Regents Planning Subcommittee

Daniel Masys, MD, co-chair, University of Washington

Jill Taylor, PhD, co-chair, NY State Department of Health

Robert Greenes, MD, PhD, Arizona State University

Eric Horvitz, MD, PhD, Microsoft Research

Sandra Martin, MSLS, Wayne State University

James Olds, PhD, National Science Foundation

NLM Strategic Planning Process

• Broad opportunity for stakeholder input– 4-5 Multidisciplinary Planning Panels of Outside

Experts

– Request for Information* on Topics/Issues identified for each Panel

– Special opportunity at MLA annual meeting

– Email: Patti.Brennan@nih.gov

• Background for developing 10-year vision– Review vision for 2025 in 2006/16 Plan:

https://www.nlm.nih.gov/pubs/plan/lrp06/report/strategicvision.html

– Solicit ‘audacious goals’ for the decade ahead.

* Previously submitted input WILL be consulted.

Advisory Committee to the Director, NIH

NLM Working Group Report, June 11, 20151. NLM must continually evolve to remain a leader in assimilating and

disseminating accessible and authoritative biomedical research findings and trusted health information to the public, healthcare professionals, and researchers across the world

2. NLM should lead efforts to support and catalyze open science, data sharing, and research reproducibility, striving to promote the concept that biomedical information and its transparent analysis are public goods

3. NLM should be the intellectual and programmatic epicenter for data science at NIH and stimulate its advancement throughout biomedical research and application

4. NLM should strengthen its role in fostering the future generation of professionals in biomedical informatics, data science, library sciences, and related disciplines through sustained and focused training efforts

5. NLM should maintain, preserve, and make accessible the nation’s historical efforts in advancing biomedical research and medicine, thereby ensuring that this legacy is both safe and accessible for long-term use

6. New NLM leadership should evaluate what talent, resources, and organizational structures are required to ensure NLM can fully achieve its mission and best allocate its resources

http://acd.od.nih.gov/reports/Report-NLM-06112015-ACD.pdf

Context for NLM Strategic Plan:

Summary results for 22,571 trials 9/21/2016

Systematic Reviewers Take Note!!

MANY not available elsewhere.

U.S. Clinical Trials Registration & Results SubmissionRulemaking Process – drug & device trials (2008-2016!! )

Announce in Unified Agenda

Agency develops draft NPRM

Departmental (HHS) review

OMB reviewPublish in Federal

Register

Public comment period

Agency response to comments

Departmental review

OMB review

Publish final rule –

Sept. 16, 2016

Congressional review

Rule takes effect

Jan. 17,2017

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New NIH Policy also covers Phase 1 and trials of ANY intervention

We are here!!

High-level Implications• Transparency

– Summary results will be reported for all FDAAA and NIH-funded trials – not subject to sponsor, investigator, or journal editor discretion

– Final rule ensures systematic reporting of trial information

• Accountability – Organizations that sponsor studies will be held responsible

for their conduct and reporting• Requires fundamental changes throughout the Clinical Research

Enterprise: funders, sponsors, investigators

– Sends an important message: The time to decide if a study is worth reporting is BEFORE any participants are put at risk, not AFTER

• More automated tools to help with submissions?

Deborah Zarin, MD and some of the terrific ClinicalTrials.gov staff

Webinar Series for Data Submitters

• Webinar #1 (September 27, 2016)– Overview and General Topics for Final Rule

• Webinar #2 (October 5, 2016)– Clinical Trial Registration Information and Update

Requirements

• Webinar #3 (October 11, 2016)– Clinical Trial Results Information and Update

Requirements

– Quality Control Review Procedures and Posting

https://clinicaltrials.gov/ct2/manage-recs/present#FinalRuleWebinar

First-time results submitters are strongly encouraged to arrange a one-on-one orientation by emailing register@clinicaltrials.gov

Courtesy of Dr. S. Silberberg, NINDS

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Reproducibility of Pre-Clinical Research

https://www.nlm.nih.gov/news/nlm_co_sponsored_conference_2016.html

New NIH grant requirements: research (2016--); training (2017--)

Training resources that may help…

http://nexus.od.nih.gov/all/category/blog/Useful perspectives on pre-clinical, clinical, and data science research issues

FY 2015 Informationist Supplements• Eleven awards issued, 18 informationists embedded in research teams,

e.g.,

• Imperato-McGinley, Julianne. CTSC Informationist Services in NIH Funded Research Projects. Weill Medical College, Cornell– Informationists Michael Bales, Terri Wheeler will build a data literacy/use component to

serve all partner instiutions; improve translational scientists' data literacy and practices; establish a governance board of library leaders from key partners.

• Pang, Xiaowu. Howard/Hopkins Intercenter Collaboration in HPV-Associated Cancer Studies. Howard U. – Informationist Young-Joo Lee will build a system to improve quality and transfer of data

in 3 pilot projects between Howard U and JHU; develop a data dictionary. Develop metadata for citing data, and identify useful visualization tools.

• Evanoff, Bradley. Washington U CTSA.– Informationists will help them improve reproducibility by interviewing researchers,

studying workflows for writing up methods and data reporting, and developing a scoring system for reproducibility of research.

Next Funding Opportunity in 2017

BD2K Open Educational Resource Grants Managed by NLM, FY 2015

• Demystifying Biomedical Big Data: A User’s Guide. Haddad, Bassem. R25 LM012285 Georgetown U

• Best Practices in Research Data Management Massive Open Online Course. Martin Elaine. R25 LM012284 U Mass Worchester

• Enabling Data Science in Biology. Lawson, Catherine. R25 LM012286 Rutgers

• Training & Tools for Informationists to Facilitate Sharing of Next Generation Sequencing Data. Seymour, Anne. R25 LM012288 JHU

• Preparing Medical Librarians to Understand and Teach Research Data Management. Surkis, Alisa. R25 LM012283 NYU

https://datascience.nih.gov/bd2k

BD2K in the Pacific NW

http://www.bigdatau.org/data-science-seminars

New series of classes coming from NLM

• Responding to growth in PubMed API use

• “The Insider’s Guide to Accessing NLM Data”

• Introducing the basics of E-utilities

• Hands-on workshops, practical solutions

• Starting October 19, 2016

– “Welcome to E-utilities for PubMed”

• For more information:

– https://dataguide.nlm.nih.gov

Progress on public access to publications

Author manuscripts now available for download – in addition to open access subset

PMC-Public Access

Participants

New (better?) measure of impact of articles

Try it at: https://icite.od.nih.gov

Consolidated Access to International Evidence

HealthReachhttps://healthreach.nlm.nih.gov

Enhancements of 2016 redesign:• Streamlined search & results• Responsive design for tablets

and mobile devices• Detailed abstracts• Listserv for new content

updates

TOXMAP Native Lands layer

https://communityhealthmaps.nlm.nih.gov/

Information for Public Health Emergencies: Zika Virus

Keep current Disaster and Public Health Emergency Research

DISASTR-OUTREACH-LIBdisasterinfo.nlm.nih.gov/dimrc/

dimrclistserv.html

EMAIL Updates Disaster Lit

TwitterNews and Announcements

Funding

Twitter@NLM_DIMRC@NLM_News

https://circulatingnow.nlm.nih.gov/

Gale Dutcher, MS, MLSActing Associate Director for

Specialized Information Services

(September 2016)

Thanks and farewell

Martha Fishel, MLSChief, Public Services Division

(June 2016)

Constantly updated sources of NLM Updates

Constantly updated sources of NLM Updates

Constantly updated sources of NLM Updates

Use API to auto-populate your website

Help recruit our future!

2016/2017 NLM Associate Fellows

You and your thoughts welcome here! -- patti.brennan@nih.gov