The Menopause The Menopause TransitionTransition

A Developmental PhaseA Developmental Phase

A Biological EventA Biological Event

DefinitionDefinition

Menopause - the complete or Menopause - the complete or permanent cessation of permanent cessation of menstruation. Interval of 12 months menstruation. Interval of 12 months of amenorrhea necessary to establish of amenorrhea necessary to establish the diagnosisthe diagnosis

Climacteric - phase during which a Climacteric - phase during which a transition is made from the transition is made from the reproductive stage of life to the reproductive stage of life to the nonreproduction stagenonreproduction stage

Hot FlashesHot Flashes• Are the most Are the most

common early common early manifistationsmanifistations

• Dizziness, Dizziness, Headaches, Headaches, pounding heart, pounding heart, sweating and night sweating and night sweatssweats

• Affecting 85% of Affecting 85% of womenwomen

OptionsOptionsHot Flashes / Night SweatsHot Flashes / Night Sweats

Prescription approachesPrescription approaches• Hormone Therapy Hormone Therapy

• Is the most effective therapyIs the most effective therapy• Decrease symptoms by 70%Decrease symptoms by 70%• Oral, patch or gelOral, patch or gel

• Smallest dose for the shortest durationSmallest dose for the shortest duration

Osteoporosis In Canadian WomenOsteoporosis In Canadian Women

100,000 fractures annually100,000 fractures annually

1/3 are hip fractures1/3 are hip fractures- 20% mortality- 20% mortality- 30-50% disability- 30-50% disability

25% over age 60 25% over age 60 - vertebral crush fractures- vertebral crush fractures

- pain, loss of height- pain, loss of height

OptionsOptionsOsteoporosisOsteoporosis

• BisphosphonatesBisphosphonates• SERMsSERMs• Hormone TherapyHormone Therapy• CalcitoninCalcitonin