Upload
jan-henry
View
213
Download
0
Embed Size (px)
Citation preview
International Review of Psychiatry (1998), 10, 58± 61
The effect of symptom self-management training on
rehospitalization for chronic schizophrenia in Finland
JAN-HENRY STENBERG,1 IIRO P. JAÈ AÈ SKELAÈ INEN2 & RUNE ROÈ YKS2
1Hesperia Hospital, Department of Adolescent Psychiatry, Helsinki & 2Unit of Psychiatry, Clinic for
Rehabilitation, Espoo, Finland
Sum mary
The effect of symptom self-management training (SSMT) was studied on several indices of quality of life, global functioning, and
on the number and length of hospitalizations in patients suffering from chronic schizophrenia in Finland. It was hypothesized that
less severe and disruptive relapses would result from the SSM T patients and their relatives being taught to recognize `warning signs’
that precede a psychotic episode and to contact medical staff before a full-blown psychosis commenced. The 29 patients receiv ing
SSMT treatment did not signi® cantly differ in quality of life or function ing from the 18 comparison patients. The number of
hospita lizations, re¯ ecting the number of relapses during the follow-up of 1± 2 years, was not different between the treatment and
comparison groups, either. However, the length of hospita lization per admission, re¯ ecting the severity of relapses, was signi ® cantly
shorter in SSM T patients.
Introduction
While antipsychotic medication is probably the main
protective factor against development of psychotic
symptoms and relapse (see Liberman, 1994),
patients on adequate doses of neuroleptic medi-
cation still have unacceptably high rates of relapse
(Hogarty, 1984). For example, patients receiving
guaranteed delivery of antipsychotic medication
through long-term, injectable or depot antipsy-
chotics, still show relapse rates of approximately
40% per year (Hogarty et al., 1986). Furthermore,
medication cannot teach patients how to cope with
a stressful life, or how to function successfully in
society (Liberman, 1994); thus, developing effective
psychosocial rehabilitation methods to complement
drug therapy is an important goal in schizophrenia
treatment research.
Symptom self-management skills training
(SSMT) is a rehabilitation method that aims to
delay, mitigate or prevent psychotic relapses in per-
sons with schizophrenia (Eckman et al., 1992;
Liberman, 1989; Marder et al., 1996). This module,
from the UCLA Social & Independent Living Skills
Program, is an educational program for teaching
schizophrenic patients and their relatives speci® c
types of knowledge and skills to help them in coping
with the disease. The topics, or skill areas, of the
module include: (1) identifying personal warning
signs of a psychotic relapse, (2) managing the warn-
ing signs with a relapse prevention plan, (3) coping
with persistent symptoms, and (4) avoiding alcohol
and street drugs. The module can be taught to
individual patients, to patients and their relatives,
and to groups.
The purpose of the present study was to investi-
gate: (1) the effect of the SSMT program on the
frequency and severity of relapses as indexed by the
number and length of hospitalizations in a Finnish
population of schizophrenics; (2) whether SSMT
affects the patients’ self-reported quality of life; and
(3) the impact of the SSMT on the global function-
ing of the patients.
Methods
Subjects
From a total of 47 hospitalized voluntary patients,
all meeting DSM-III-R criteria for schizophrenia,
who participated in their standard and individual-
ized treatment programs, 29 were assigned to also
participate in the SSMT program, during 1992±
1994, in the Clinic for Rehabilitation, at Jorvi Hos-
pital, in Espoo, Finland. Patients receiving SSMT
and standard treatment were matched into three
sub-groups on the basis of the starting point of the
SSMT program, with a resulting length of follow-up
assessm ents ranging from 1± 2 years. As shown in
Table 1, there were no statistically signi® cant differ-
ences between the SSMT and matched control
groups in sex, age, marital status, level of education,
diagnostic sub-type, age of onset of schizophrenia,
the number of prior hospitalizations, and the time
spent in mental hospital per hospitalization.
Based on self-report and con® rmed by medical
chart review, the medication of the patients was
classi® ed into four categories: (1) conventional neu-
roleptic; (2) atypical neuroleptic (clozapine); (3)
antianxiety; and (4) antidepressant drugs. There
Correspondence to: Rune Royks, MA, Unit of Psychiatry, Clinic for Rehabilitation, Postipuuntie 2, FIN-02600, Espoo,Finland. Tel: 1 358 9 861 7520. Fax 1 358 9 861 7535.
0954± 0261/98/010058± 04 $7.00 Ó 1998, Institute of Psychiatry
Int R
ev P
sych
iatr
y D
ownl
oade
d fr
om in
form
ahea
lthca
re.c
om b
y U
nive
rsity
of
Auc
klan
d on
11/
06/1
4Fo
r pe
rson
al u
se o
nly.
Symptom self-management training in schizophrenia 59
Table 1. Demographic variables of SSM T and control patients. Values are presented as mean
( 6 SEM ), or as frequencies
Variable SSMT Control
Total number of patients 29 18Male female ratio 17/12 10/8Age 35.3 6 1.5 32.4 6 2.3Age of onset of schizophrenia 24.9 6 1.1 21.7 6 1.5Number of hospitalizations (in weeks) 7.2 6 0.6 11.2 6 2.4Length of hospitalizations (in weeks) 4.9 6 0.7 6.6 6 1.4Number of patients on antipsychotics all allNumber of patients on adjunctive benzodiazepines 23/29 13/18Number of patients on antidepressants 5/29 none
Table 2. The self-and staff-rated variables for the SSMT and control patients
SSMT Controls
Self-rated variablesContentment with treatment 7.6 6 0.4 6.7 6 0.3Bene® t of treatment 7.6 6 0.3 7.6 6 0.3Contentment of present state of life 6.8 6 0.4 6.8 6 0.5
ª 2 years ago 5.6 6 0.4 6.1 6 0.7ª 2 years from now 7.4 6 0.3 6.8 6 0.8
Support of family 7.4 6 0.4 7.8 6 0.5Capability to identify warning signs 7.4 6 0.4 6.6 6 0.5Capability to cope with illness 6.6 6 0.4 6.3 6 0.8Alcohol consumption (standard drinks) 3.1 6 0.8 1.8 6 0.8Quality of life scale 7.8 6 0.3 6.5 6 0.6
Staff-rated variablesQuality of life scale 7.2 6 0.3 6.1 6 0.6GAF evaluation 42.8 6 1.9 39.4 6 2.1
were no statistically signi® cant differences between
the SSMT and control groups’ medication during
the study.
Assessments
The data were gathered by interviewing the patients,
analyzing their medical histories, and asking the
treatment staff to evaluate the interviewed on their
personal assessments of outcome with a semistruc-
tured format, using a 10-point Likert scale
(10 5 highest). The following self- and staff-
reported variables were gathered: (1) the patient’ s
contentment with his/her present treatment; (2) the
patient’ s estimation of the bene® t of his/her present
treatment; (3) the patient’ s contentment with his/
her present state of life; (4) the patient’ s content-
ment with his/her state of life before the SSMT; (5)
the patient’ s estimation of contentment with life two
years after the interview; (6) the patient’ s estimation
of support by his/her family; (7) the patient’ s esti-
mation of his/her capability to identify the warning
signs of the illness; (8) the patient’ s estimation of
his/her capability to cope with the disease; and (9)
consumption of ethyl alcohol (estimated in standard
drinks (12g of ethanol per drink).
Further, they were asked to evaluate their quality
of life (Spitzer et al., 1981). In addition, the treat-
ment staff evaluated the patients’ global functioning
with the GAF Scale and patients’ quality of life with
the same scale used by patients in their self-report.
The interviews and evaluations were made, with
three months accuracy, 2.0, 1.5 or 1.0 years after
the SSMT program. The number and duration of
patients’ hospitalizations were recorded for follow-
up periods of 2.0, 1.5 or 1.0 years after the SSMT
program.
Data analysis
The statistical analysis was conducted with two-
factor ANOVAs, with repeated measures on the last
factor. The factors were treatment (SSMT patients
versus controls), and length of follow-up.
Results
The self- and staff-reported ratings of quality of life,
and ratings of global functioning did not
signi® cantly differ between the SSMT and the con-
trol groups. In Table 2 are presented the values of
the self- and staff-report ratings.
The length of follow-up (2.0, 1.5 and 1.0 years)
signi® cantly in¯ uenced neither the number of hospi-
talizations nor the time spent in hospital per hospi-
talization. Further, the number of hospitalizations
was not signi® cantly different between the SSMT
Int R
ev P
sych
iatr
y D
ownl
oade
d fr
om in
form
ahea
lthca
re.c
om b
y U
nive
rsity
of
Auc
klan
d on
11/
06/1
4Fo
r pe
rson
al u
se o
nly.
60 Jan-Henry Stenberg et al.
Figure 1. The time (in weeks) spent in 24-hour mental hospita l per hospitalization by patients with symptom self-management training
and by control patients treated with only conventional methods. The two groups did not signi ® cantly differ in baseline, but the SSMT
patients’ average time spent in hospital per hospitalization was signi® cantly shorter during the follow-up period, compared with the control
group (n 5 29 for the treatment group, and n 5 18 for the control group; error bars disclose the SEM ).
and the control groups (SSMT 5 1.9 6 0.3; con-
trols 5 2.7 6 1.2). The length of treatment per hos-
pitalization was, however, signi® cantly shorter in the
SSMT group than for the control group, as shown
in Figure 1, [F(1,41) 5 13.7, p , 0.001].
Discussion
Although there were some statistically insigni® cant
tendencies towards higher scores in self- and staff-
reported indices of the quality of life and global
functioning in the SSMT patients compared with
controls, no clear differences were observed between
the groups. The number of hospitalizations was not
signi® cantly different between the SSMT and con-
trol patients, either. The average length of hospital-
izations was, however, signi® cantly shorter in the
SSMT patients, compared with controls. In fact, the
schizophrenics who had participated in SSMT spent
only about 2.6 weeks in a mental hospital per
admission during the follow-up period of 1.0 ± 2.0
years, whereas the control patients’ corresponding
® gure was 20.1 weeks.
Tentatively, we might infer that this ® nding of less
severe and briefer relapses might have been related
to one of the central goals of SSMT; namely, teach-
ing the patients and their relatives to recognize
speci® c `warning signs’ that had preceded their prior
episodes of schizophrenic psychoses (e.g. insomnia,
restlessness) and to contact medical staff in case the
frequency of the occurrence of the signs increased
(Liberman, 1989). Consequently, the SSMT
patients could be admitted to mental hospital while
still being in the prodromal phase of their relapses,
compared with the controls, thus explaining the
longer periods of hospitalization needed by the con-
trols for a suf® cient recovery to allow clinical
improvement. This is consistent with recent ® ndings
from a controlled clinical trial of the Symptom and
Medication Management modules with low dose
¯ uphenazine decanoate (Marder et al., 1996).
It has to be noted that in Finland the treatment of
psychiatric patients involves relatively easy access to
24-hour hospital care. Thus, a major psychotic epi-
sode is not necessarily required for admittance, but
short hospitalizations may be used in monitoring
patients with prodromal or relatively mild signs of
relapse, and for preventing severe decompensations.
The data of the present study do not, however,
allow a rigorous analysis of the causal factors under-
lying the shorter length of hospitalization per relapse
in SSMT patients, and thus this needs to be
addressed in future investigations. In fact, the sever-
ity of psychopathology was only indirectly and glo-
bally rated in this study; hence, it is not even
possible to equate each hospitalization to a symp-
tomatic relapse or exacerbation (Falloon & Liber-
man, 1983).
Acute psychotic relapse in schizophrenia may lead
to a long-lasting loss of functional capacity, which
Int R
ev P
sych
iatr
y D
ownl
oade
d fr
om in
form
ahea
lthca
re.c
om b
y U
nive
rsity
of
Auc
klan
d on
11/
06/1
4Fo
r pe
rson
al u
se o
nly.
Symptom self-management training in schizophrenia 61
produces disability and may predispose individuals
to future relapses. Thus, given the detrimental role
of relapses in chronic schizophrenia, the SSMT
treatment may have bene® cial long-term effects in
the treatment of this disorder in that it appears to
confer protection, along with antipsychotic medi-
cation and other conventional rehabilitation meth-
ods, for the patient in avoiding further psychotic
episodes.
Acknowledgements
The authors acknowledge Marjukka Stenberg for
helpful comments on the paper. The authors thank
also the nursing staff of Jorvi Hospital, Department
of Psychiatry, who have helped in this study.
References
ECKMAN, T.A., W IRSCHING, W.C., MARDER, S.R., LIBER-
MAN, R.P., JOHNSTON-CRONK, K., ZIMMERM ANN, K. &MINTZ, J. (1992). Technique for training schizophrenicpatients in illness self-management: a controlled trial.American Journal of Psychiatry, 149(11), 1549± 1555.
FALLOON, I.R.H. & LIBERMAN, R.P. (1983). Interactionsbetween drug and psychosocial therapy in schizophre-nia. Schizophrenia Bulletin , 9, 543± 554.
HOGARTY, G.E. (1984). Depot neuroleptics: the relevanceof psychosocial factorsÐ a United States perspective.Journal of Clinica l Psychiatry, 45, 36± 42.
HOGARTY, G.E., ANDERSON, G.M., REISS, D.J., KORN-
BLITH, S.J., GREENWALD , D.P., JAVNA, C.D. & MADO-
NIA, M.J. (1986). Family psychoeducation, social skillstraining and maintenance chemotherapy in the aftercaretreatment of schizophrenia. Archives of Genera l Psy-
chiatry, 43, 633± 642.LIBERMAN, R.P. ( 1989.) Socia l & Independent Living
Skills. The Symptom M anagement Module. Availablefrom Psychiatric Rehabilitation Consultants, 528 LakeSherwood Drive, Thousand Oaks, California 91361,USA.
LIBERMAN, R.P. (1994). Psychosocial treatments forschizophrenia. Psychiatry, 57, 4± 114.
MARDER, S.R., W IRSCHING, W.C., M INTZ, J., MCKENZIE,R.N., JOHNSTON, K., ECKMAN, T.A., LEBELL, M., ZIM-
MERMAN, K. & L IBERMAN, R.E. (1996). Two-year out-come of social skills training and group psychotherapyfor outpatients with schizophrenia. American Journa l of
Psychiatry, 153112, 585± 597.SPITZER, W.O., DOBSON, A.J., HALL, I., CHESTERM AN, E.,
LEVI, J., SHEPHERD, R., BATTISTA, R. & CATCHLOVE, B.(1981). Measuring the quality of life of cancer patients.A concise QL-index for use by physicians. Journal of
Chronic Diseases, 34, 585± 597.
Int R
ev P
sych
iatr
y D
ownl
oade
d fr
om in
form
ahea
lthca
re.c
om b
y U
nive
rsity
of
Auc
klan
d on
11/
06/1
4Fo
r pe
rson
al u
se o
nly.