Subject index

CANCER LETTERS

Cancer Letters 83 (1994) 331-336

Subject index

Volume 83 (1994)

Aberrant crypt foci; Chemoprevention; Costunolide; Ses-

quiterpene; Azoxymethane; Intestine; Rat 83, 171

Aberrant crypt foci; Docosahexaenoic acid; Azoxymethane;

Rat colon carcinogenesis 83, 177

Abnormal splicing; CD44; Gastric carcinoma; Metastasis 83,

229

Acinsl cell carcinogenesis; 4-Hydroxyaminoquinoline I-oxide;

8-Hydroxyguanine; Acinar cell necrosis; Oxidative stress;

Rat 83, 97

Acinar cell necrosis; 4-Hydroxyaminoquinoline l-oxide; 8-

Hydroxyguanine; Acinal cell carcinogenesis; Oxidative

stress; Rat 83, 97

Adenine; Renal cell tumor; Promotion; Nephropathy 83, 105

Albumin; RNA splicing; Mutation; Analbuminemic rat;

Minigene; Hepatoma cells 83, 221

Analbuminemic rat; RNA splicing; Mutation; Minigene; Albu-

min; Hepatoma cells 83, 121

Androgen-independence; Prostate carcinogenesis; Rat; Testos-

terone 83, 111

Angiogenesis; hst-I; FGF family; CAM assay; Cornea

assay 83, 261

Animal model; Hereditary cancer; Two-hit model; Tumor sup-

pressor gene; Tumor spectrum 83, 1 I7

Antbralin; FK506; Skin tumor promotion; Interleukin-la 83, 185

Anti-oncogenic potential; IRF-I; c-myc; fosB 83, 191

Antigenotoxicity; Drosophila; Cu-chlorophyllin 83, 157

Antioxidant; Mammary carcinogenesis; Rat; Green tea catechin 83, 149

Ascorbic acid; Vitamin C; Helicobacter pylori; Gastric pH;

Chronic gastritis; Lewis blood-group system 83. 323

Autocrine mechanism; Carcinogenesis; Hepatocyte growth fac-

tor; HGF; Lung carcinoma; MET oncogene 83, 235

Azodye; Hepatocarcinogenesis; Dose effect; Histopathology; Rat 83, 59

Azoxymethane; Chemoprevention; Costunolide; Sesquiterpene;

Intestine; Aberrant crypt foci; Rat 83, 171

Azoxymethane; Docosahexaenoic acid; Aberrant crypt foci; Rat colon carcinogenesis 83, 177

Benz[a]anthracene; Human; Dihydrodiols; Diol epoxides: Me-

tabolism; Microsomes 83, 299

Black tea; Food carcinogen; Heterocyclic amine; Prevention,

formation; Green tea: Theaflavine gallate: Epigallocatechin

gallate; Creatinine 83, 143

Bladder carcinoma; Prohibitin; Rat; FANFT; Saccharin 83,

201

BrdU; Rat; Intestine; Cell proliferation; Laxatives 83, 43

Breast tumor; Chalcone; Chemoprevention: Suppressing agent;

Chemical carcinogenesis; Lung tumor 83, 165

5-Bromo-2’deoxyuridine (BrdU); 22-0xa-1,25(OH)zvitamin

D,; Rat hepatocarcinogenesis; Glutathione S-transferase

placental form 83, 69

c-fos; c-V2JX; N-Methyl-N’-nitro-N-nitrosoguanidin e;

Taurocholate; Rat stomach 83, 215

0304-3835/94/$07.00 0 1994 Elsevier Science Ireland Ltd. All rights reserved

332 Subject indev/Cancrr Lrtt. c13 i 1994) 331-336

c-myc; C-J& N-Methyl-N’nitro-N-nitrosoguanidin e; Chemical carcinogenesis; Chalcone; Chemoprevention: Sup- Taurocholate; Rat stomach 83, 215 pressing agent; Lung tumor; Breast tumor 83. 165

c-myc; IRF-I; Anti-oncogenic potential; f&B 83, 191 Chemicals; History; Carcinogenesis 83. 9

CAM assay; hst-I; FGF family: Angiogenesis; Cornea assay 83, 261

Chemoprevention: Chalcone; Suppressing agent; Chemical carcinogenesis; Lung tumor; Breast tumor 83. 165

Cancer chemi-prevention; Cancer prevention; Electrophile

generation; Oxidative DNA damage; Cellular proliferation: Regulation 83. 15

Chemoprevention; Costunolide; Sesquiterpene; Azoxymethane;

Intestine; Aberrant crypt foci: Rat 83, 171

Cancer prevention; Electrophile generation; Oxidative DNA

damage; Cellular proliferation; Cancer chemi-prevention; Regulation 83. 15

Chimeric mice; Clonal growth; N-Methyl-N-nitrosourea; Glan-

dular stomach cancer 83, 37

Chronic gastritis; Ascorbic acid; Vitamin C; Helicobacfer

pylori; Gastric pH; Lewis blood-group system 83, 323 Cancer prevention; Risk factors; Genetics; Environmental car-

cinogens 83. 139 cis-Diamminedichloroplatinum (II); 32P-postlabelling; DNA ad-

ducts 83. 129 Capsaicin; Nitrophenols; Capsicum annum 83, 277

Capsicum annum; Nitrophenols; Capsaicin 83, 277 Clotihrate; Peroxisome proliferator; Preneoplastic liver cell

foci; GST-P positive foci; Rapid bioassay for carcinogens;

Rat liver 83, 89 Carcinogenesis; Autocrine mechanism; Hepatocyte growth fac-

tor; HGF; Lung carcinoma; MET oncogene 83, 235 Clonal growth; Chimeric mice; N-Methyl-N-nitrosourea; Glan-

dular stomach cancer 83, 37 Carcinogenesis; History; Chemicals 83, 9

Carcinogenesis of mouse skin; Protein kinase C isoforms; Skin tumors 83. 245

Codon 63; Thyroid carcinoma; N-Bis(2-hydroxypropyI)-

nitrosamine; Ki-ras oncogene; Point mutation; Rat 83. 209

Carcinogenic hazards, ranking of; Carcinogenic potency;

Dietary heterocyclic amine; Species comparison 83, 21 Cornea assay; hst-I: FGF family; Angiogenesis; CAM

assay 83, 261

Carcinogenic potency; Dietary heterocyclic amine; Carcino-

genic hazards, ranking of; Species comparison 83. 21 Costunolide; Chemoprevention; Sesquiterpene; Azoxymethane;

Intestine; Aberrant crypt foci; Rat 83, 171

Carcinogenicity; MeIQx; Dose-response; Rat 83, 3 1

CD44: Abnormal splicing; Gastric carcinoma; Metastasis 83.

229

Creatinine; Food carcinogen; Heterocyclic amine; Prevention,

formation; Green tea; Black tea: Theaflavine gallate;

Epigallocatechin gallate 83, 143

Cu-chlorophyllin; Drosophila; Antigenotoxicity 83, 157 cDNA expression; Phenanthrene metabolism; Human;

Cytochrome P-450: High-pressure liquid chroma-

tography 83, 305 Cytochrome P-450; Phenanthrene metabolism; Human; cDNA

expression: High-pressure liquid chromatography 83. 305

Cell line; Mouse; Liver; Hepatocellular tumor; Gene expres-

sion; Differentiation 83, 269

Cell proliferation; Ra; Intestine; BrdU; Laxatives 83, 43

Dietary heterocyclic amine; Carcinogenic potency; Carcino-

genic hazards, ranking of; Species comparison 83, 21

Differentiation; Mouse; Liver; Hepatocellular tumor; Gene expression; Cell line 83. 269

Cellular proliferation; Cancer prevention; Electrophile genera-

tion; Oxidative DNA damage: Cancer chemi-prevention; Regulation 83. 15

Dihydrodiols; Benz[a]anthracene; Human; Diol epoxides: Me-


Chalcone; Chemoprevention; Suppressing agent; Chemical carcinogenesis; Lung tumor; Breast tumor 83. 165

1,2_Dimethylhydrazine; Estrogen: Uterine sarcoma; Hemor-

rhagic ovarian lesion 83, 51

Subject index/Cancer Lett. 83 (1994) 331-336 333

Dial epoxides; Benz[a]anthracene; Human; Dihydrodiols; Me-


Dissociation of foci and oval cell proliferation; Preneoplastic

foci; ‘Oval cell’ proliferation; Liver cell carcinogenesis: Ductular cell proliferation 83, 75

DNA adduct; Wood preserving waste extract; 32P-

Postlabelling; Radical and direct-acting toxicant; Risk

assessment 83, 123

DNA adducts; “P-postlabelling; cis-Diamminedichloro- platinum (II) 83, 129

DNA repair; Immunohistochemistry; UV-photoproducts;

Monkey skin 83, 291

Docosahexaenoic acid; Aberrant crypt foci; Azoxymethane; Rat colon carcinogenesis 83, 177

Dose effect; Hepatocarcinogenesis; Azo-dye; Histopathology; Rat 83, 59

Dose-response; MeIQx; Carcinogenicity; Rat 83, 31

Drosophifa; Cu-chlorophyllin; Antigenotoxicity 83, 157

Ductular cell proliferation; Preneoplastic foci; ‘Oval cell’ prolif-

eration; Dissociation of foci and oval cell proliferation;

Liver cell carcinogenesis 83, 75

Electrophile generation; Cancer prevention; Oxidative DNA

damage; Cellular proliferation; Cancer chemi-prevention;

Regulation 83, I5

Environmental carcinogens; Cancer prevention; Risk factors; Genetics 83, 139

Epidermal differentiation; Multistage carcinogenesis; Protein kinase C isoforms; 12-O-Tetradecanoyl phorbol-l3-acetate;

Tumor promotion; Murine keratinocytes 83, 249

Epigallocatechin gallate; Food carcinogen; Heterocyclic amine;

Prevention, formation; Green tea; Black tea; Theallavine gallate; Creatinine 83. 143

Estrogen; l.2-Dimethylhydrazine; Uterine sarcoma; Hemor- rhagic ovarian lesion 83, 51

PANFT; Prohibitin; Bladder carcinoma; Rat; Saccharin 83,

201

FGF family; hs/-I; Angiogenesis; CAM assay; Cornea assay 83, 261

FK506; Anthralin; Skin tumor promotion; Interleukin-la 83,

185

Foci of altered hepatocytes; Hepatic preneoplasia; Radiation

carcinogenesis; o-Irradiation; Neutron 83, 8 1

Food carcinogen; Heterocyclic amine; Prevention, formation;

Green tea; Black tea; Theaflavine gallate: Epigallocatechin

gallate; Creatinine 83. 143

fosB; IRF-1; Anti-oncogenic potential; c-myc 83, 191

Gastric carcinoma; CD44; Abnormal splicing; Metastasis 83,

229

Gastric pH; Ascorbic acid; Vitamin C; Helicobacter pylori; Chronic gastritis; Lewis blood-group system 83. 323

Gene expression; Mouse; Liver; Hepatocellular tumor; Differ- entiation; Cell line 83, 269

Genetics; Cancer prevention; Risk factors; Environmental car-

cinogens 83, 139

Glandular stomach cancer; Clonal growth; Chimeric mice; N-

Methyl-N-nitrosourea 83, 37

Glutathione S-tvansferase placental form; 22-Oxa-

1,25(0H)2vitamin D3; Rat hepatocarcinogenesis; 5-Bromo-

2’-deoxyuridine (BrdU) 83, 69

Green tea; Food carcinogen; Heterocyclic amine; Prevention, formation; Black tea; Theaflavine gallate; Epigallocatechin


Green tea catechin; Mammary carcinogenesis; Rat; Antioxi-

dant 83, 149

GST-P positive foci; Clofibrate; Peroxisome proliferator; Preneoplastic liver cell foci; Rapid bioassay for carcinogens;

Rat liver 83, 89

Helicobacrer pylon’; Ascorbic acid; Vitamin C; Gastric pH;

Chronic gastritis; Lewis blood-group system 83, 323

Hemorrhagic ovarian lesion; Estrogen; l,2-Dimethylhydrazine;

Uterine sarcoma 83, 51

Hepatc preneoplasia; Foci of altered hepatocytes: Radiation carcinogenesis; a-Irradiation; Neutron 83, 8 1

Hepatocarcinogenesis; Azo-dye; Dose effect; Histopathology;

Rat 83, 59

Hepatocellular tumor: Mouse; Liver; Gene expression; Differ-

entiation; Cell line 83. 269

Hepatocyte growth factor; Autocrine mechanism; Car- cinogenesis; HGF; Lung carcinoma; MET oncogene 83. 235

334 Subject irdes / Cancer L~/I. 83 (lYY4i 331-336

Hepatoma cells; RNA splicing; Mutation; Analbuminemic rat;

Minigene; Albumin 83. 221

Hereditary cancer; Two-hit model; Animal model; Tumor sup-

pressor gene; Tumor spectrum 83, 117

Heterocyclic amine; Food carcinogen; Prevention, formation;

Green tea; Black tea; Theaflavine gallate; Epigallocatechin

gallate; Creatinine 83. 143

HGF; Autocrine mechanism; Carcinogenesis: Hepatocyte

growth factor; Lung carcinoma; MET oncogene 83, 235

High-pressure liquid chromatography: Phenanthrene metabolism; Human; Cytochrome P-450: cDNA expression 83.

305

Histopathology; Hepatocarcinogenesis; Azo-dye; Dose effect;

Rat 83, 59

History; Carcinogenesis; Chemicals 83, 9

Ztsfst-I; FGF family; Angiogenesis; CAM assay; Cornea assay 83, 261

Human: Benz[a]anthracene; Dihydrodiols; Diol epoxides; Me-


Human; Phenanthrene metabolism; Cytochrome P-450; cDNA

expression; High-pressure liquid chromatography 83, 305

4-Hydroxyaminoquinoline l-oxide; &Hydroxyguanine: Acinar

cell necrosis; Acinal cell carcinogenesis; Oxidative stress:

Rat 83, 97

ISHydroxyguanine; 4-Hydroxyaminoquinoline l-oxide; Acinar cell necrosis; Acinal cell carcinogenesis; Oxidative stress;

Rat 83, 97

Immunohistochemistry; UV-photoproducts; DNA repair: Mon- key skin 83, 291

Interleukin-lor; Anthralin; FK506; Skin tumor promotion 83. 185

Intestine; Chemoprevention; Costunolide; Sesquiterpene:

Azoxymethane; Aberrant crypt foci; Rat 83. 171

Intestine; Rat; Cell proliferation; BrdU: Laxatives 83. 43

IRF-1; Anti-oncogenic potential; c-m~c; /??osZ? 83. 191

a-Irradiation; Hepatic preneoplasia; Foci of altered hepatocytes; Radiation carcinogenesis; Neutron 83, 8 1

Ki-ras oncogene; Thyroid carcinoma; N-Bis(2-hydroxypropyl).

nitrosamine; Codon 63; Point mutation; Rat 83, 209

Laxatives; Rat; Intestine; Cell proliferation: BrdU 83. 43

Lewis blood-group system; Ascorbic acid; Vitamin C;

Helicobacter p.v/ori; Gastric pH; Chronic gastritis 83, 323

Liver; Mouse; Hepatocellular tumor; Gene expression; Differ-


Liver cell carcinogenesis: Preneoplastic foci; ‘Oval cell’ prolifer-

ation; Dissociation of foci and oval cell proliferation; Duc-

tular cell proliferation 83. 75

Liver tumor promoter; Okadaic acid class compounds; Protein phosphatases 1 and 2A 83, 283

Lung carcinoma; Autocrine mechanism; Carcinogenesis: Hepa-

tocyte growth factor; HGF; MET oncogene 83, 235

Lung tumor; Chalcone; Chemoprevention; Suppressing agent;

Chemical carcinogenesis; Breast tumor 83. 165

Mammary carcinogenesis; Rat; Green tea catechin: Antioxi- dant 83. 149

MeIQx; Carcinogenicity; Dose-response; Rat 83. 31

MET oncogene; Autocrine mechanism; Carcinogenesis; Hepa-

tocyte growth factor; HGF; Lung carcinoma 83. 235

Metabolism; Benz[a]anthracene; Human: Dihydrodiols: Diol epoxides; Microsomes 83. 299

Metastasis; CD44: Abnormal splicing: Gastric carcinoma 83.

229

Microsomes; Benz[a]anthracene; Human; Dihydrodiols; Diol epoxides; Metabolism 83, 299

Minigene: RNA splicing; Mutation; Analbuminemic rat: Albu- min; Hepatoma cells 83, 321

Monkey skin; lmmunohistochemistry: UV-photoproducts:

DNA repair 83. 291

Mouse; Liver; Hepatocellular tumor; Gene expression; Differ-


Multistage carcinogenesis; Protein kinase C isoforms: 12-O

Tetradecanoyl phorbol-13.acetate; Tumor promotion; Murine keratinocytes; Epidermal differentiation 83. 249

Murine keratinocytes; Multistage carcinogenesis; Protein kinase C isoforms; I?-0-Tetradecanoyl phorbol-13-acetate; Tumor promotion; Epidermal differentiation 83. 249

Mutagenesis; E-Oxoguanine: E-Oxoadenine: 06-

Methylguanine: Translesional synthesis 83. 315

Subject indes / Cancer Lett. 83 (1994) 331-336 335

Mutation; RNA splicing; Analbuminemic rat; Minigene; Albu-

min; Hepatoma cells 83, 221

32P-Postlabelling; Wood preserving waste extract; DNA ad-

duct; Radical and direct-acting toxicant; Risk assess-

ment 83, 123

N-Bis(Z-hydroxypropyl~nitrosamine: Thyroid carcinoma; Ki- ras oncogene; Codon 63; Point mutation; Rat 83, 209 g.53 gene mutation; Stepwise progression; Tumour heterogene-

ity; Nodule-in-nodule hepatocellular carcinoma 83, 197

N-Methyl-N-nitrosourea; Clonal growth; Chimeric mice; Glan-

dular stomach cancer 83. 37 Pathological; Neoplasia; Reaction 83, 3

N-Methyl-N’-nitro-N-nitrosoguani dine;

Taurocholate; Rat stomach 83, 215

c-fos; c-myc; Peroxisome proliferator; Clofibrate; Preneoplastic liver cell foci; GST-P positive foci; Rapid bioassay for carcinogens;

Rat liver 83, 89

Neoplasia; Pathological; Reaction 83. 3

Nephropathy; Renal cell tumor; Promotion; Adenine 83, 105

Phenanthrene metabolism; Human; Cytochrome P-450; cDNA

expression; High-pressure liquid chromatography 83, 305

Neutron: Hepatic preneoplasia; Foci of altered hepatocytes;

Radiation carcinogenesis; o-Irradiation 83, 81

Point mutation; Thyroid carcinoma: N-Bis(2-hydroxypropyI)-

nitrosamine; Ki-ras oncogene; Codon 63; Rat 83. 209

Nitrophenols; Capsaicin; Capsicum annum 83. 277

Nodule-in-nodule hepatocellular carcinoma; Stepwise progres-

sion; Tumour heterogeneity; ~53 gene mutation 83, 197

Preneoplastic foci; ‘Oval cell’ proliferation; Dissociation of foci

and oval cell proliferation; Liver cell carcinogenesis; Duc- tular cell proliferation 83, 75

l2-O-Tetradecanoyl phorbol-H-acetate; Multistage carcinogenesis; Protein kinase C isoforms; Tumor promotion;

Murine keratinocytes; Epidermal differentiation 83, 249

Preneoplastic liver cell foci; Clofibrate; Peroxisome prolifera-

tor; GST-P positive foci; Rapid bioassay for carcinogens; Rat liver 83, 89

06-Methylguanine: Mutagenesis; 8-Oxoguanine; 8-

Oxoadenine; Translesional synthesis 83. 315

Prevention, formation; Food carcinogen; Heterocyclic amine;

Green tea; Black tea; Theaflavine gallate; Epigallocatechin


Okadaic acid class compounds; Liver tumor promoter; Protein

phosphatases I and 2A 83. 283

Prohibitin; Bladder carcinoma: Rat; FANFT: Saccharin 83.

201

‘Oval cell’ proliferation; Preneoplastic foci; Dissociation of foci

and oval cell proliferation; Liver cell carcinogenesis; Duc-

tular cell proliferation 83. 75

Promotion; Renal cell tumor; Adenine; Nephropathy 83. 105

Prostate carcinogenesis; Rat; Testosterone; Androgen-

independence 83. 1 I I

22-0xa-1,25(OH)zvitamin D,; Rat hepatocarcinogenesis; Protein kinase C isoforms; Multistage carcinogenesis; It-O- Glutathione S-transferase placental form; 5-Bromo-2’- Tetradecanoyl phorbol-l3-acetate; Tumor promotion; deoxyuridine (BrdU) 83. 69 Murine keratinocytes; Epidermal differentiation 83, 249

Oxidative DNA damage; Cancer prevention; Electrophile generation; Cellular proliferation; Cancer chemi-

prevention; Regulation 83. 15

Protein kinase C isoforms; Skin tumors; Carcinogenesis of

mouse skin 83, 245

Oxidative stress; 4-Hydroxyaminoquinoline I-oxide; 8- Hydroxyguanine: Acinar cell necrosis; Acinal cell car-

cinogenesis; Rat 83, 97

Protein phosphatases I and 2A; Liver tumor promoter; Okadaic

acid class compounds 83, 283

Radiation carcinogenesis; Hepatic preneoplasia; Foci of altered

hepatocytes; a-Irradiation; Neutron 83. 81 t?-Oxoadenine; Mutagenesis; 8-Oxoguanine; Ob-Methyl-

guanine; Translesional synthesis 83. 315

goxoguanine; Mutagenesis; 8-Oxoadenine; @-Methyl- guanine; Translesional synthesis 83, 3 I5

3*P-postlabelling; DNA adducts; cis-Diammine-

dichloroplatinum (II) 83, 129

Radical and direct-acting toxicant; Wood preserving waste ex-

tract; s*P-Postlabelling; DNA adduct; Risk assess-

ment 83. 123

Rapid bioassay for carcinogens; Clofibrate; Peroxisome prolifer-

ator; Preneoplastic liver cell foci; GST-P positive foci: Rat

liver 83, 89

336 Subject index/Cancer Leit. 83 (1994) 331-336

Rat; 4-Hydroxyaminoquinoline l-oxide; 8-Hydroxyguanine;

Acinar cell necrosis; Acinal cell carcinogenesis; Oxidative stress 83, 97

Sesquiterpene; Chemoprevention; Costunolide; Azoxymethane; Intestine; Aberrant crypt foci; Rat 83, I71

Rat; Chemoprevention; Costunolide; Sesquiterpene; Azox-

ymethane; Intestine; Aberrant crypt foci 83, 171

Skin tumor promotion; Anthralin; FK506; Interleukin-la 83,

185

Rat;

I ,2S(OH)zvitamin D,; Glutathione S-transferase placental form; 5-Bromo-2’-

deoxyuridine (BrdU) 83, 69

Thyroid carcinoma;

C-W2yC; N-Methyl-N’-nitro-N-

e; Taurocholate 215 Tumor Hereditary cancer; model; Animal

Tumor suppressor 83. 117

Neoplasia; Pathological 3

Regulation; prevention; Electrophile Oxida- tive damage; Cellular Cancer chemi-

83. 15

suppressor gene; cancer; Two-hit Ani-

mal Tumor spectrum 117

Tumour Stepwise progression; gene muta- Nodule-in-nodule hepatocellular 83, 197

cell tumor; Adenine; Nephropathy 105

Risk Wood preserving extract; 3’P-

DNA adduct; and direct-acting

cant 83,

Two-hit model; cancer; Animal Tumor sup-

gene; Tumor 83. 1

Uterine sarcoma; l.2-Dimethylhydraine; Hemor-

ovarian lesion 51

Risk Cancer prevention; Environmental car- 83, 139

lmmunohistochemistry; DNA Mon- key 83, 291

splicing; Mutation; rat; Minigene;

min; Hepatoma 83, 221

C: Ascorbic Helicobacter pylori; pH; Chronic Lewis blood-group 83, 323

Prohibitin; Bladder Rat; FANFT

201

Wood waste extract; DNA ad-

Radical and toxicant; Risk ment 83.

Documents

Subject index