Subject Index

A

Aluminum chloride, see Poliovirus Anticellular serum, see Enteroviruses Arthropod-borne viruses, (see also Dengue virus) ;

plaque assay of dengue and other group B --- under methyl cellulose overlay media, Schulze and Schlesinger, 40

Avian myeloblastosis virus, assay and multiplica- tion of - - -, Vogt and Rubin, 92

B

Bacteriophage, structural alterations of - pro- tein synthesized in the presence of ribonuclease, Jeener and Vansanten, 169; two functions in lysogenation process : repression of - multipli- cations and incorporation of prophage in bac- terial genome, Zichichi and Kellenberger, 450

Bacteriophage X, cooperative infect,ion by host modified - - , Paigen and Weinfeld, 565

Bacteriophage 480, specialized transduction of tryptophan markers in E. coli K12 by - - , Matsushiro, 475

Bacteriophage +X174, see Bacteriophage S1S Bacteriophage Pl, mapping of galactose genes of

E. coli by transduction with - - , Adler and Kaiser, 117

Bacteriophage Pf2 rd 1, affinity of - -for prophage sites on chromosome of E. coli strain C, Six, 375

Bacteriophage 513, genetic recombination be- tween - - and +X174, Tessman and Shleser, 239

Bacteriophage T2, photooxidative elimination of head form transition in - - , Cummings, 536

Bacteriophage T4, mutants of - - with increased sensitivity to ultraviolet, Harm, 66

Bacteriophage T5, deoxyribonucleic metabolism in - - infected E. coli, Lanni and McCorquo- dale, 72

Brome mosaic virus, stabilization of - - - by magnesium and calcium, Brakke, 367

5-Bromodeoxyuridine, see Vaccinia virus

C

Calcium, see Brome mosaic virus Chromatography, see ECHO 7 virus, and potato

virus X Cocoa swollen-shoot virus, use of protein in ex-

traction - - - - from cocoa leaves, Brunt and Kenten, 388

Coliphage, see Bacteriophage, and prophage Cytomegalovirus, human - , cytochemical ob-

servations of intracellular lesions correlated with viral synthesis and release, McAllister et al., 521; - assay by counting infected cells, Good- heart and Jaross, 532

D

Dengue virus, plaque assay of - - and other group B arthropod viruses under methyl cellu- lose overlay media, Schulze and Schlesinger, 40; inhibition of infectious and hemagglutinating properties of type 2 - - by aqueous agar ex- tracts, Schulze and Schlesinger, 49

Deoxyribonucleic acid, (see also Ribonucleic acid) ; biochemistry of vaccinia-infected mouse fibro- blasts. III. radioautographic and biochemical studies of thymidine-Hsuptake into - -of cells in primary culture, Kit et al., 13; - - metabo- lism in T5-infected E. coli: biochemical function of a presumptive genetic fragment of the phage, Lanni and McCorquodale, 72; viral and cellular -- synthesis in pseudorabies virus infected cells in the logarithmic phase of growth, Kaplan and Ben-Porat, 205; physical characteristics of polyoma virus. II. - - , Crawford, 279; - - content of equine abortion virus, Darlington and Randall, 322; viral protein and - - syn- thesis in vaccinia virus infected HeLa cell cultures, Salzman et al., 542; - - synthesis in vaccinia virus infected HeLa cells, Shatkin and Salzman, 551; properties of fowlpox --, Szy- balski etal., 586

Dische diphenylamine reagent, see Potato leaf-roll virus

E

Eastern equine encephalomyelitis virus, see Inter- feron

ECHO 7 virus, chromatography of high molecular weight RNA from isolated FL cells infected with - - - , Fukada and Kawade, 409

Electron microscopic studies, see Venezuelan equine encephalitis virus, herpes virus, rinderpest virus, tobacco mosaic virus, and GAL virus

Enteroviruses, antigenic variation in amnion cells in relation t’o inhibition of - by anticellular serum, Timbury, 501

Equine abortion virus, nucleic acid content of - - - , Darlington and Randall, 322

Equine herpes virus, see Herpes virus

602 SUBJECT INDEX

F

Fowlpox virus, properties of - - DNA, Szybalski etal., 586

G

GAL virus, structure of capsid of - - , Davies, 418

Genetic studies, see Bacteriophage, bacteriophage X, bactiophage 480, bacteriophage Pl, bacteriophage Pa rd 1, and bacteriophage SlS

H

Herpes virus, surface difference between virions of two strains of - - , Roiaman and Roane, Jr., 198; electron microscopic particle counts on - -using the phosphotungstate negative stain- ing technique, Watson et al., 250; role of polyoma virus and interferon in - - infection in vitro, Glasgow and Habel, 328; equine - - , Plum- mer and Waterson, 412; reversible inhibition of - - multiplication in HEp-2 cells with phen- ethyl alcohol, Roizman, 580

Human cytomegalovirus, see Cytomegalovirus Hydroxylamine, see Tobacco mosaic virus

I

Influenza virus, (see also Interferon); role of the surface state in the morphogenesis of - - fila- ments, Blough, 112

Interferon, optimal temperature for growth and sensitivity to - , Ruiz-Gomez and Isaacs, 1; - production by different viruses, Ruiz-Gomez and Isaacs, 8; studies on - in two lines of HeLa cells, Cantell and Paucker, 81; - studies. II. temporal relationships of virus and - produc- tion by cells infected with Eastern equine encephalomyelitis and influenza viruses, Wag- ner, 215; vaccinia virus plaque formation and inhibition by - I. dynamics of plaque forma- tion by vaccinia virus, Lindenmann and Gifford, 283; plaque formation by vaccinia virus in presence of - , Gifford et al., 294; III. simplified plaque inhibition assay of - , Lindemann and Gifford, 302; polyoma virus and - in a herpes simplex virus infection in vitro, Glasgow and Habel, 328

J

Japanese encephalitis virus noninfectious hemag- glutinin and complement fixing antigen of - - - B, Kitaoka and Nishimura, 238; kinetic studies on neutralization reaction between --- and antiserum, Hashimoto and Prince, 261

1

Lipids, studies of - of virus-infected cells. I. - analysis of a soluble hemagglutinin from vac- cinia virus infected chorioallantoic membranes, Gaush and Youngner, 573

Lucerne mosaic virus, properties of purified prep- arations of - - - , Gibbs et al., 441

Lytic interaction, see Polyoma virus

M

Magnesium, see Brome mosaic virus Malignant cells, “morphologically normal” cells

with properties of - -, Defendi eta!!., 592 Measles virus, hemagglutination by - - . III.

identification of two different hemagglutinins, Norrby, 147

Mumps virus, see Sindbis virus

Myxovirus, effect of vitamin A alcohol on morphol- ogy of - . I. production and comparison of artificially produced filamentous virus, Blough, 349

N

Newcastle disease virus, chemical mutagenesis of - - - , Thiry, 225

Nucleic acid, see Deoxyribonucleic acid, and ribo- nucleic acid

0

Ornithosis virus, subcellular cultivation of - - in nonnucleate cytoplasm, Cracker and Enst- wood, 23

P

Phage, see Bacteriophage, and prophage Phenethyl alcohol, see Herpes virus Photooxidation, see Bacteriophage T2 Picornavirus group, - - , Melnick et al., 114 Poliovirus, influence of - infection on RNA

synthesis in mammalian cells, Fenwick, 241; interaction of - RNA with E. coli ribosomes, Warner et al., 393; RNA synthesis in - infected cells, Zimmerman et aZ., 400; heat inactivation of infectious RNA of - and tobacco mosaic virus, Gordon et al., 416; selection of attenuated - from virulent suspensions by heating in aluminum chloride, Wallis and Melnick, 483; quantitative study of - antigens in HeLa cells, Scharff and Levintow, 491

Polyoma virus, - - variant with new antigenic determinants, Hare and Morgan, 105; lyt,ic in- teraction and cell transformation with large- and small-plaque mutant of - - , Medina and Sachs, 127; purification of - - , Winocour, 158; physical characteristics of - - . II. nu- cleic acid, Crawford, 279; - - and interferon in herpes simplex virus infection in vitro, Glas- gow and Habel, 328; phvsical characteristics of

- III. correlation with biological activities, Abel and Crawford, 470

Potato leaf-roll virus, reaction of Dische diphenyl- amine reagent with sap from pot,ato plants in- fected with - - - - , Govier, 561

SUBJECT INDEX 603

Potato virus X, chromatographic studies on plant viruses. I. isolation of - - - by various sys- tems of adsorption chromatography, Venekamp and Mosch, 316

Prophage, see Bacteriophage Prophage P2 (see also Bacteriophage P&d I);

localization of - - in two strains of E. co/i, Kelly, 32

Protein (see also Deoxyribonucleic acid) ; structural alterations of phage - synthesized in the pres- ence of ribonuclease, Jeener and Vansanten, 169; use of - in extraction of cocoa swollen- shoot virus from cocoa leaves, Brunt and Ken- ten, 388

Pseudorabies virus, viral and cellular DNA syn- thesis in - - infected cells in the logarithmic phase of growth, Kaplan and Ben-Porat, 205

R

Reovirus, hemagglutination with - , Lerner et al. 58

Ribonuclease, see Protein Ribonucleic acid, fractionation of infectious - -

from tobacco mosaic virus, Miura et al., 140; influence of poliovirus infection on - - syn- thesis in mammalian cells, Fenwick, 241; inter- action of poliovirus - -with E. coli ribosomes, Warner et al., 393; - - synthesis in poliovirus infected cells, Zimmerman et al., 400; chroma- tography of high molecular weight - -from FL cells infected with ECHO 7 virus, Fukada and Kawade, 409; heat inactivation of infectious - - of polio and tobacco mosaic viruses, Gor- don et al., 416; inactivating and mutagenic ac- tion of hydroxylamine on tobacco mosaic virus, Schuster and Wittman, 421

Ribosomes, see Ribonucleic acid Rinderpest virus, electron microscopy of - - in

kidney tissue culture cells, Breese, Jr., and De Boer, 340

s

Simian virus 40, transformation in hamster kidney monolayers by - - - , Black and Rowe, 107; biophysical studies on simian papova virus particle, - - - , Mayor et al., 359

Sindbis virus, - - plaque size in cell cultures treated with mumps virus infected egg fluids, Frothingham, 533

Surface act’ive agents, see InfEuenza virus

T

Thymidine, see Deoxyribonucleic acid Tobacco mosaic virus, fractionation of infectious

ribonucleic acid from - - - , Miura et al., 140; similarity in accumulation of - - - in systemic and local necrotic infection, Tani- guchi, 237; electron microscopy of - - - par- ticles from aphid stylets, Matsui et al., 411;

heat inactivation of infectious RNA of polio- virus and - - - , Gordon et al., 416; inactivat- ing and mutagenic action of hydroxylamine on --- ribonucleic acid, Schuster and Wittman, 421; cytochemical study of tobacco leaf cells infected with - - - , Takahashi and Hirai, 431; timing of early events following inoculation with - - - , Fry and Matthews, 461

Tobacco necrosis virus, further studies of Olpidium as a vector of - - - , Teakle and Gold, 310

Transduction, see Bacteriophage Pi, and bacteri- ophage $230

Transformation, see Simian virus 40, and polyoma virus

Turnip yellow mosaic virus, kinetics of labelling of - - - - with P32 and S36, Matthews et al., 179; relationship between - - - - and wild cucumber mosaic virus, Macleod and Markham, 190

U

Ultraviolet irradiation studies, see Bacteriophage 7'4

V

Vaccinia virus, biochemistry of - - mouse fibro- blasts. III. radioautographic and biochemical studies of thymidine-H3 uptake into DNA of cells in primary culture, Kit et al., 13; - -plaque formation and its inhibition by interferon. I. dynamics of plaque formation by - - , Linden- mann and Gifford, 283; II. plaque formation by - - in presence of interferon, Gifford et al., 294; III. simplified plaque inhibition assay of interferon, Lindemann and Gifford, 302; effect of 5-bromodeoxyuridine on - - multiplication, Easterbrook and Davern, 509; viral protein and DNA synthesis in - - infected HeLa cells, Salzman et al., 542; DNA synthesis in - - in- fected HeLa cells, Shatkin and Salzman, 551; lipid analysis of a soluble hemagglutinin from - -infected chorioallantoic membranes, Gaush and Youngner, 573

Vacuolating virus, see Simian virus 40 Varicella virus, localization of - - in tissue cul-

ture, Slotnick and Rosanoff, 589 Venezuelan equine encephalitis virus, electron

microscopic demonstration of purified - - - - , Mussgay and Weibel, 109

Visna virus, growth cycle of - - in sheep cell monolayer cultures, Thormar, 273

Vitamin A, see Myxovirus

W

Wheat striate mosaic virus, mechanical transmis- sion of - - - - to its leafhopper vector, Lee, 88

Wild cucumber mosaic virus, see Turnip yellow mosaic virus