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Sound A unique, new-generation steroid makes otitis externa simpler to treat. Provides the 3-way action needed to treat otitis externa. Anti-inflammatory (hydrocortisone aceponate) Antifungal (miconazole nitrate) Antimicrobial (gentamicin sulfate) Features Functions Benefits a) Contains hydrocortisone aceponate (HCA) a new generation, highly fat soluble, steroid that is significantly more potent than hydrocortisone a) That allows it to rapidly penetrate the skin, activate locally and accumulate in the target tissue. a) This high persistent anti- inflammatory activity with low systemic side effect extends the therapeutic effect beyond the 5-day dosing duration. b) Precise delivery system b) That reliably delivers an exact 1mL dose each time. b) Eliminates drop counting and provides enough drug to completely coat the ear canal of any size or breed of dog. c) In addition to HCA also contains gentamicin sulfate and miconazole nitrate c) Which are proven antimicrobial and antifungal agents… c) …that provide the 3-way action needed to quickly and effectively treat otitis externa. d) Award-winning ergonomically designed applicator. d) Canister can be used at any angle and has a soft, pliable nozzle that is gentle to sensitive ear structures. d) Makes administration less frustrating and enhances client compliance. Indication: EASOTIC Otic Suspension for Dogs is indicated for the treatment of otitis externa in dogs associated with susceptible strains of yeast ( Malassezia pachydermatis) and bacteria (Staphylococcus pseudintermedius). Important safety information: EASOTIC Otic Suspension for Dogs is contraindicated in dogs with known or suspected hypersensitivity to corticosteroids, imidazole antifungals, or aminoglycoside antibiotics. Do not use in dogs with known tympanic membrane perforation. The safe use of EASOTIC Otic Suspension for Dogs in dogs used for breeding purposes, during pregnancy, or in lactating bitches has not been evaluated. See brief summary for additional product information.

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Page 1: Sound - Vet Advantage

Sound

A unique, new-generation steroid makes otitis externa simpler to treat.

Provides the 3-way action needed to treat otitis externa.

Anti-inflammatory (hydrocortisone aceponate)

Antifungal (miconazole nitrate)

Antimicrobial (gentamicin sulfate)

Features Functions Benefitsa) Contains hydrocortisone

aceponate (HCA) a new generation, highly fat soluble, steroid that is significantly more potent than hydrocortisone

a) That allows it to rapidly penetrate the skin, activate locally and accumulate in the target tissue.

a) This high persistent anti-inflammatory activity with low systemic side effect extends the therapeutic effect beyond the 5-day dosing duration.

b) Precise delivery system b) That reliably delivers an exact 1mL dose each time.

b) Eliminates drop counting and provides enough drug to completely coat the ear canal of any size or breed of dog.

c) In addition to HCA also contains gentamicin sulfate and miconazole nitrate

c) Which are proven antimicrobial and antifungal agents…

c) …that provide the 3-way action needed to quickly and effectively treat otitis externa.

d) Award-winning ergonomically designed applicator.

d) Canister can be used at any angle and has a soft, pliable nozzle that is gentle to sensitive ear structures.

d) Makes administration less frustrating and enhances client compliance.

Indication: EASOTIC Otic Suspension for Dogs is indicated for the treatment of otitis externa in dogs associated with susceptible strains of yeast (Malassezia pachydermatis) and bacteria (Staphylococcus pseudintermedius). Important safety information: EASOTIC Otic Suspension for Dogs is contraindicated in dogs with known or suspected hypersensitivity to corticosteroids, imidazole antifungals, or aminoglycoside antibiotics. Do not use in dogs with known tympanic membrane perforation. The safe use of EASOTIC Otic Suspension for Dogs in dogs used for breeding purposes, during pregnancy, or in lactating bitches has not been evaluated. See brief summary for additional product information.

Page 2: Sound - Vet Advantage

ContaCt us for more information at 1-800-338-3659

ConfidenceI am convinced that easOtIc Otic suspension for Dogs provides the quickest and most effective treatment of otitis externa available in the market today. Invitation (neutral)

Let me explain the key benefits…

It’s the Customer’s Decision …and then you can decide if easOtIc Otic suspension for Dogs should be your preferred treatment for your patients with otitis externa.

QualifyIdentify if a Virbac representive has been in recently:

Doctor, has the Virbac rep introduced you to their new easotiC otic suspension for Dogs treatment?If yes, review understanding and reinforce benefits. If no, detail as the primary contact.

CHeCK-off &eCHo notes

Sound

References: 1. Guaguere E, Bensignor E, Carlotti DN, et al. Clinical practice guidelines on the best use of

topical glucocorticoids in canine dermatology. Prat Med Chir Anim Comp. 2011;46:S1–S20.2. Schackert C, Korting HC, Schafer-Korting M. Qualitative and quantitative assessment of the benefit/risk ratio of medium

potency topical corticosteroids in vitro and in vivo. BioDrugs. 2000;13(4):267–277.3. Schafer-Korting M, Gysler A. Topical glucocorticoids with improved benefit/risk ratio. In: Korting HC, Schafer-Korting M, eds. The

Benefit/Risk Ratio: A Handbook for The Rational Use of Potentially Hazardous Drugs. Boca Raton, FL: CRC Press; 1999:359–372. 4. Riguat D, Sanquer A, Maynard L, Reme CA. Efficacy of a topical ear formulation with a pump delivery system for the treatment of

infectious otitis externa in dogs: a randomized clinical trial. Intern J Appl Res Vet Med. 2011;9(1):15–28. 5. Mori M, Pimpenelli N, Gannott B. Topical corticoids and unwanted local effects, improving the benefit/risk ratio. Drug Safety. 1994;10:406–412. 6. Boda C, Liege P, Reme C. Evaluation of owner compliance with topical treatment of acute otitis externa in dogs: a comparative study

of two auricular formulations. Intern J Appl Res Vet Med. 2011;19(2):157–165.

© 2014 Virbac Corporation. All Rights Reserved. EASOTIC is a registered trademark of Virbac S.A. All other trademarks are the property of their respective owners.

EAsy 5-dAy TrEATMEnTpowered by hydrocortisone aceponate (hca).

Unlike older-generation glucocorticoids, the metabolism of HCA occurs in the skin and exhibits high local efficacy and a low risk of systemic side effects.1,5

The unique characteristics of this new-generation steroid

are the key to shorter treatment regimens

hca is highly lipid soluble, resulting in:1

Quick and effective dose concentrations reached in epidermis and dermis2,3

persistence in target tissue that extends the therapeutic effect beyond the 5-day dosing duration4

hca is activated and metabolized in the skin, allowing for:

higher concentrations in the skin than with conventional treatments4

potent anti-inflammatory effects with better local and systemic tolerance than conventional treatments2

easotic otic suspension for dogs:Contains HCA, a new-generation steroid that enables simple, 5-day treatment regimens

Delivers potency of conventional topical treatments with low risk of systemic side effects1

Delivers an exact 1-mL dose with a single pump

Contains proven antimicrobial and antifungal agents

Features an ergonomically designed applicator that makes administration less frustrating and enhances client compliance

EASOTIC®

(hydrocortisone aceponate, miconazole nitrate, gentamicin sulfate) Otic Suspension for Dogs6

Surolan®

(miconazole nitrate, polymyxin B sulfate,

prednisolone acetate)6

DOG OWNERS

COMPLIANTDOG OWNERS

COMPLIANT

79% 21%