Solutions for Drug Discovery, Development and ProductionSample Preparation and Analysis

R & D

Process Development

Formulation

QC Analysis

Solutions for Sample Prep

Advancing Science Through Discovery

Increase your laboratory workflow productivity with high capacity sample processing.AVANTI JXN SERIES CENTRIFUGES

• Increase productivity with the (6L) JLA-8.1000 or the (4L) JLA-9.1000 fixed angle rotor.

• Flexibility with remote monitoring and control from your Apple® iOS and Android™ device with MobileFuge.

• Detailed run history and rotor tracking by serial number.

• Perfect for shared labs and GMP environment support. Password protection allows appropriate security levels.

• Backward compatibility with the existing Avanti rotor library.***

• Optional HarvestLine System Liners for JLA-8.1000 and JLA-9.1000 rotors—no need to scrape out the pellet and transfer; just remove the liner and seal it.

Achieve the speed and optimum performance for your ultra-speed processing applications.OPTIMA X SERIES ULTRACENTRIFUGES

• Total system design – The Optima X Series, its rotors and its labware are designed, manufactured and tested as an integrated system to ensure optimal performance and safety for your lab.

• Powerful on-board simulation calculation tools (XPN Only) optimizes protocols before running.

• Real-time run graphing – Plots speed and temperature over time, allowing you to track and record progress.

• Security and tracking features (XPN only). Password protection and electronic signatures.

• Vast rotor library for your application needs.

CELLULAR | VIROLOGY | PROTEOMICS | NANOTECHNOLOGY WORKFLOWS

Solutions for Sample Analysis

Quickly obtain automated cell viability, concentration and size distribution results from your cell culture.VI-CELL XR* CELL VIABILITY ANALYZER

• For cell and tissue culture applications requiring accuracy, precision, and automation.

• The Vi-CELL cell viability analyzer provides an automatic and cost-effective method to perform the Trypan Blue dye exclusion method.

• The Cell Type feature provides the ability to optimize for specific cell lines.

• The sample carousel provides ability to load samples on the fly.

• The Bioprocess Tracking feature allows convenient, automated tracking of your cell culture parameters essential for optimum bioreactor production.

Accurately acquire high resolution sizing, counting, and size distribution results down to sub-cellular level.MULTISIZER 4E* COULTER COUNTER

• Precisely measures volume, size, and concentration (counts, density) for every particle or cell.

• Label free detection of sub-cellular particles, large protein aggregates, bacteria, cells, spheroids and more.

• Overall size range of 200 nm to 1600 µm.

Get rapid, simultaneous analysis of both particle size and zeta potential from your small sample.DELSAMAX PRO* LIGHT SCATTERING ANALYZER

• Ideal for formulation and stability testing of biological therapeutics.

• Determine particle size or aggregation in samples as small as 1 µL.

AUC provides versatile and accurate means for determining molecular weight, hydrodynamic and thermodynamic properties of a protein or a macromolecule.OPTIMA AUC* ANALYTICAL ULTRACENTRIFUGE

• Applications: molecular weight, stoichiometry, protein aggregation, ligand binding, conjugation efficiency and polydispersity.

• Advantages: sample recovery, no dilution required, matrix free, minimal buffer constraints, detection at low concentration, low sample volume (0.1 mL minimum), high throughput and no standards required.

Have the versatilty to consistently analyze your various sample types, dry or liquid, from nm to µm size range.LS 13 320 SERIES* LASER DIFFRACTION PARTICLE SIZE ANALYZER

• Measure unknown sample distributions without guessing the type of distribution to preprogram the instrument.

• Particle size measurement from 0.017 µm to 2,000 µm.

• Four interchangeable modules: Aqueous Liquid Module (ALM), Micro Liquid Module (MLM), Tornado Dry Powder System (DPS), and Universal Liquid Module (ULM).

• Easy-to-follow Standard Operating Methods (SOM’s).

• Multi-component Standard Operating Procedures (SOP’s).

CELLULAR | VIROLOGY | PROTEOMICS | NANOTECHNOLOGY WORKFLOWS

COMING

SOON†

* Not for Diagnostics Use. ** BioSafe and BioSafety are terms intended to describe the enhanced biocontainment features of our products. *** Please refer to the Avanti JXN Series User Guide for the list of compatible rotors. † Optima AUC is in development. Beckman Coulter, the stylized logo, and the Beckman Coulter product and service marks mentioned herein are trademarks

or registered trademarks of Beckman Coulter, Inc. in the United States and other countries. All other trademarks are the property of their respective owners. Apple is a registered trademark of Apple, Inc. iOS is a trademark or registered trademark of Cisco in the U.S. and other countries

and is used under license. Android is a trademark of Google, Inc.

For Beckman Coulter’s worldwide office locations and phone numbers, please visit “Contact Us” at beckmancoulter.com CENT-1573FLY05.16-A ©2016 Beckman Coulter, Inc.

Designed specifically for ISO 14644 cleanroom applicationsMET ONE 3400* PORTABLE AIR PARTICLE COUNTER

• Organize your cleanroom monitoring – Embedded location and sample recipe management.

• Intuitive user interface – Easy area, location, operating parameter configuration and replication.

• 21 CFR Part 11 compliance – Full electronic records direct from the counter via wireless Ethernet – eliminate paper- based results and manual data transcriptions

• Unit-to-unit accuracy and reproducibility – Assured through ISO 21501-4 compliance.

Beckman Coulter’s BioSafe** Centrifugation Systems• Beckman Coulter’s BioSafe** centrifugation systems

are equipped with a pharmaceutical-grade sterilizing filter system.

• Alleviates concern regarding the escape of unwanted particles from inside the centrifuge into vaccine production environment.

• Filter components have met the specifications for biological tests listed in the current revision of the United States Pharmacopeia (USP) for Class VI-121 °C plastics and bacterial retention in conformance with the applicable requirements of the FDA Guideline Sterile Drug Products Produced by Aseptic Processing-Current Good Manufacturing Practice.

Solutions for CleanroomsCELLULAR | VIROLOGY | PROTEOMICS | NANOTECHNOLOGY WORKFLOWS