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Slide 1 of 31
Chemistry 24.3
© Copyright Pearson Prentice Hall
Slide 2 of 31
24.3 Amino Acids and Their Polymers
Many people are lactose intolerant. These people cannot digest milk products because their bodies do not produce enough of the enzyme lactase to digest lactose, the sugar found in milk. You will learn what enzymes are and what function they serve in the body.
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Amino Acids and Their Polymers >
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24.3 Amino Acids
Amino Acids
What is the general structure of an amino acid?
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24.3 Amino Acids and Their Polymers > Amino Acids
An amino acid is any compound that contains an amino group (—NH2) and a carboxyl group (—COOH) in the same molecule.
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Amino Acids and Their Polymers >24.3 Amino Acids
Amino acids have a skeleton that consists of a carboxyl group and an amino group, both of which are covalently bonded to a central carbon atom. The remaining two groups on the central carbon atom are hydrogen and an R group that constitutes the amino acid side chain.
Slide 6 of 31
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24.3 Amino Acids and Their Polymers > Amino Acids
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Amino Acids and Their Polymers >
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24.3 Peptides
Peptides
Which functional groups are always involved in amide bonds between amino acids?
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24.3 Amino Acids and Their Polymers > Peptides
A peptide is any combination of amino acids in which the amino group of one amino acid is united with the carboxyl group of another amino acid.
Slide 9 of 31
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24.3 Amino Acids and Their Polymers > Peptides
The amide bond between the carboxyl group of one amino acid and the nitrogen in the amino group of the next amino acid in the peptide chain is called a peptide bond.
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Amino Acids and Their Polymers >24.3 Peptides
The amide bonds between amino acids always involve the central amino and central carboxyl groups. The side chains are not involved in the bonding.
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Amino Acids and Their Polymers >
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24.3 Proteins
Proteins
What determines the differences in the chemical and physiological properties of peptides and proteins?
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24.3 Amino Acids and Their Polymers > Proteins
A peptide with more than about 100 amino acids is called a protein.
• Your skin, hair, nails, and muscles are made of protein.
• Proteins are needed for almost all chemical reactions that take place in the body.
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24.3 Amino Acids and Their Polymers > Proteins
Amino Acids in a Peptide Chain
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24.3 Amino Acids and Their Polymers > Proteins
Sections of a peptide chain may coil into a regular spiral, known as a helix.
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24.3 Amino Acids and Their Polymers > Proteins
Peptide chains may also be arranged side by side to form a pleated sheet.
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Amino Acids and Their Polymers >24.3 Proteins
Differences in the chemical and physiological properties of peptides and proteins result from differences in the amino acid sequence.
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24.3 Amino Acids and Their Polymers > Proteins
The Shape of Myoglobin
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Amino Acids and Their Polymers >
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24.3 Enzymes
Enzymes
How do enzymes affect the rates of reactions in living things?
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24.3 Amino Acids and Their Polymers > Enzymes
Enzymes are proteins that act as biological catalysts.
Enzymes increase the rates of chemical reactions in living things.
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24.3 Amino Acids and Their Polymers > Enzymes
The enzyme urease hydrolyzes urea, a constituent of urine, into ammonia and carbon dioxide.
Slide 21 of 31
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24.3 Amino Acids and Their Polymers > Enzymes
How Enzymes Work
Enzymes catalyze most of the chemical changes that occur in the cell.
• Substrates are the molecules on which an enzyme acts.
• The place on an enzyme where a substrate binds is called the active site.
Slide 22 of 31
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24.3 Amino Acids and Their Polymers > Enzymes
In a typical enzymatic reaction, the substrate interacts with side chains of the amino acids on the enzyme. These interactions cause the making and breaking of bonds.
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24.3 Amino Acids and Their Polymers > Enzymes
An HIV particle (red) infects a human white blood cell (orange). The diagram models the enzyme HIV protease.
Slide 24 of 31
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24.3 Amino Acids and Their Polymers > Enzymes
The enzyme carbonic anhydrase catalyzes the reversible breakdown of carbonic acid to carbon dioxide and water.
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24.3 Amino Acids and Their Polymers > Enzymes
Coenzymes
Coenzymes are metal ions or small organic molecules that must be present for an enzyme-catalyzed reaction to occur.
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24.3 Amino Acids and Their Polymers > Enzymes
The enzyme catalase includes an iron(III) ion in its structure. Catalase catalyzes the breakdown of hydrogen peroxide to water and oxygen.
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Section Quiz
-or-Continue to: Launch:
Assess students’ understanding of the concepts in Section
24.3 Section Quiz.
24.3.
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24.3 Section Quiz.
1. Choose the correct words for the spaces. An amino acid is a compound having the ________ group and the _________ group bonded to a central carbon atom.
a. carboxyl, amino
b. carbonyl, amide
c. amino, peptide
d. carbohydrate, amide
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Slide 29 of 31
24.3 Section Quiz.
2. Choose the correct words for the space. A protein is a peptide with ___________ amino acids linked in a chain.
a. more than about 100
b. less than about 100
c. two
d. zero
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Slide 30 of 31
24.3 Section Quiz.
3. Enzymes affect biochemical reactions by
a. changing the equilibrium position of the system.
b. acting as catalysts to speed up the reaction.
c. being consumed as the reaction progresses.
d. decreasing the size of competing substrates.
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Slide 31 of 31
24.3 Section Quiz.
4. Some vitamins participate in biological processes as
a. peptides.
b. amino acids.
c. enzymes.
d. coenzymes.
END OF SHOW