Session+ 22+ +Norms+and+Ethics+ +Part+2

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    Analysis of EmergingTechnologies

    Legal / Norms / Ethics

    November 19, 2013

    1

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    Bitcoin

    http://blockchain.info/charts/market-priceExchange rate has increased by 3x since in two weeks.

    There are plenty of opportunities fordigital currencies to operate withinexisting laws and regulations.

    Edward Lowery, a special agent with theSecret Service, which is tasked withprotecting the integrity of the dollar

    Congressional hearings on Bitcoin promised in the wake of the Silk Road seizure inOctober. Those occurred Monday.

    http://dealbook.nytimes.com/2013/11/18/regulators-see-value-in-bitcoin-and-investors-hasten-to-agree/

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    Shaping Use to Eliminate Slack

    High occupancy toll (HOT) lanes on I-85implemented in 2011.

    Toll changes dynamically to ensure traffic at 45 mph ormore. The cost for the entire stretch reached $8.50 onNov. 5.

    To use the lane, you pay a toll. You must register andaffix a transponder to your windshield. Transponder ispolled at intervals by sensors installed along the lane.

    3+ person car pools can ride free; requires checking

    your toll mode.

    http://www.ajc.com/news/news/i-85-hot-lane-toll-hits-record-850/nbhpY/

    Why was this implemented?

    As a new regressive tax on an already taxpayer-funded road.

    To profile drivers. (The NSA is watching)

    To provide incentives to carpool and/or shift when people drive. The roads are often

    clogged (rush hour), but they often have ample unused (slack) capacity.

    To guarantee a free-flowing lane of traffic for those willing to pay for it.--

    Plans to build HOT lanes on I-75 south (Henry /Clayton Counties) and I-75 north (Cobb County.)

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    Shaping Use to Eliminate Slack

    Similar issue with electricity. Green line shows electricity supply. Red line shows

    electricity demand. Supply must be over-provisioned to meet peak demand. Same

    thing occurs with highways/roads. Graphic from the California Integrated System Operator for August 22, 2006.

    Blue line represents more consistent

    electricity use.

    A key challenge is getting

    available supply (i.e., road

    capacity) to line up with demand

    (i.e., the number of cars.)

    5:30 p.m. 7:30 p.m. 5:30 p.m. 7:30 p.m.

    This would

    be better

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    (Some) Methods to Avoid Over-Provisioning

    How to Avoid

    Overprovisioning of Supply?Supply

    Demand

    Smoothed Demand /

    Supply

    1) Batteries

    Produce at a consistent level; storewhat isnt used for later use.(Potentially use electric car batteries here.)

    2) Demand Shifting

    Create incentives to shift demand sothat demand stays flat.

    http://www.nytimes.com/2013/07/17/business/energy-environment/battery-seen-as-way-to-cut-heat-related-power-losses.html

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    Demand Shifting and Variable Pricing

    Utility changing electricity prices basedon time of day, demand, or other factors.

    Would provide incentive forhomeowners to shift consumption to

    times when prices are lower. E.g.,run the dishwasher or charge thehouses auxiliary battery at 3:00 a.m.

    Need to automate homeowners capacity to handle this. Topic is called

    demand response.

    One element here is smart meters: Communicateswirelessly with the utility. Allows for automated (and continuous) meter

    reading. Allow the utility to tell the homeowners meter the

    current price of electricity. Meter (or supplementary control device) can

    (theoretically) act as a hub, directing applianceswhen to operate, when to run in low-power mode,

    etc.

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    Shaping Use to Eliminate Slack

    Basic idea is to use available resources optimally, eliminating the need togenerate excess resources. Options include:

    Identify, aggregate, and make available

    underutilized sources of supply. Resources oftenare unused (spare rooms, tools, vehicles) andavailable. The Internet makes this easier thanbefore.

    Smooth demand to limit over-provisioning forpeaks. (I.e., shave peaks to fill valleys). Dynamicpricing is one way to incentivize this. Advances ininformation technology make this possible in agrowing range of fields.

    E.g., Peach Pass identifies andbills customers wirelessly anddynamically. System could

    help smooth demand byshifting when people drive.

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    8

    Identify theTechnology

    Consider theTechnology andthe System in

    Which i t Operates

    MakePredictions /

    IdentifyOpportunities

    Forecasting Tools

    Invention

    Innovation diffusion andtechnology acceptance

    Technology platforms, network

    effects, and standardsInfrastructure and stakeholderimpact

    Sustainability, legal, and

    regulatoryEthics and norms

    General Framework for the Course

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    23andMe Services Offered

    Does my profileresemble other23andMe customers?

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    23andMe Business Model

    Why only $99? Is thatprofitable?

    Asks people to opt-in to anonymous data sharing for research purposes. Surveysmembers to correlate experiences with DNA (e.g., have you had swine flu? Do you thinkcilantro tastes like soap?)

    Offers a free test to anyone diagnosed with Parkinsons disease; recruited more than10,000 people. How to monetize this type of data?

    23andMe is not yetprofitable. The most value

    may lie in the databasethey are amassing.

    The long game here is not to make money selling kits,although the kits are essential to get the base level data.Once you have the data, [the company] does actuallybecome the Google of personalized health care.

    Patrick Chung, 23andMeboard member

    http://www.fastcompany.com/3018598/for-99-this-ceo-can-tell-you-what-might-kill-you-inside-23andme-founder-anne-wojcickis-dna-r

    More than 200 million questions have been answered by 23andMe members.

    Identify people who are atrisk for Alzheimers before

    symptoms manifest,permitting clinical trials ofdrug therapies before thedisease advances too far.

    Partner with countries with

    single-payer health systems.

    Let's say you genotype everyone in Canada the

    government is able to identify those segments of thepopulation that are most at risk for Parkinson's. Youcan target them with preventative messages, make surethey're examined more frequently, and in the end livehealthier lives, and the government will save massive(health care) expenses...

    Chung

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    Compare your DNA to that of others

    Analyzed men and womens DNA, focusing on the genes that comprise themajor histocompatability complex (MHC.) These genes affect immunity.The poorer the match, the greater the attraction.

    http://www.youtube.com/watch?v=-drpViV5LSw (0:12 to 2:06, 2:25 to 4:01)

    Original experiment by Claus Wedekind, Bern University in late 1990s.Who you are attracted to (in this case, via smell) is a function of your DNA (andthe DNA of the other party.)

    1 2354

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    The Evolutionary Perspective

    No overlap =high

    attraction

    Completeoverlap = low

    attraction

    Male

    Female

    Serves as a proxy for kinship; may help prevent inbreeding.

    Other benefits besides babies with better immune systems include lesslikelihood of infidelity, more happiness, etc

    Children of this pair will have a wide range

    of genes and thus of immune responses.

    Children of this pair will have a

    narrow range of genes.

    How do you profit from this?

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    Partners with dating web sites. Theidea is to match you with someonewith whom you are biologicallycompatible.http://www.genepartner.com/

    For $249, you get a self DNA test (you swab your mouth)

    that you send back in. That information is used to matchyou.

    GenePartner.com

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    Another Scenario

    Once you find the partner, would you be interested in his / her argininevasopressin receptor 1a gene?

    Youre looking for your perfect match.

    Do you swab your mouth and have your DNA analyzed by GenePartner.com or23andMe? (Rhetorical)

    Study published in the Proceedings of the National Academy of Sciences found

    that men who had two copies of a variant of the gene (RS3 334) were less likelyto be married and more likely to report difficulties in their relationships.

    Laboratory mice have been genetically engineered to be monogamous(they arent normally.)

    Raises the possibility that infidelity can bepredicted, and perhaps, treated.

    http://opinionator.blogs.nytimes.com/2008/09/16/a-commitment-pill/?_r=0

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    Technology and Ethics

    Item

    Parentsofchildrendiagnosedwithattentiondeficitdisorderprovidetheirchildrenwith

    psychostimulant drugstoimprovetheirfocusandcognitivefunction.

    ParentsofchildrenNOTdiagnosedwithattentiondeficitdisorderprovidetheirchildrenwith

    psychostimulant drugsto

    improve

    their

    focus

    and

    cognitive

    function.

    AbaseballplayerundergoesLasiksurgerytoimprovehisbatting.

    Abaseballplayerusessteroidstoimprovehisbatting.

    Researchersgeneticallymodifyacowtoproducemilkwithnobetalactoglobulin,whichisthe

    protein

    believed

    to

    trigger

    allergic

    reactions

    in

    2

    3%

    of

    infants.Researchersgeneticallyengineerabaldchicken(i.e.,nofeathers)toreducethecostofchicken

    meatproduction.

    FirstResponseTM augmentsitsathomepregnancyteststoincludeatestforwhetherababywill

    haveTaySachsdisease.

    FirstResponseTM augments

    its

    at

    home

    pregnancy

    tests

    to

    include

    atest

    for

    whether

    ababy

    will

    beaboyoragirl.

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    Technology and Ethics

    Item Avg. Histogram

    Parentsofchildrendiagnosedwithattentiondeficitdisorderprovidetheirchildren

    withpsychostimulant drugstoimprovetheirfocusandcognitivefunction.

    2.7

    ParentsofchildrenNOTdiagnosedwithattentiondeficitdisorderprovidetheir

    childrenwith

    psychostimulant drugs

    to

    improve

    their

    focus

    and

    cognitive

    function.

    7.4

    AbaseballplayerundergoesLasiksurgerytoimprovehisbatting. 3.1

    Abaseballplayerusessteroidstoimprovehisbatting. 8.0

    Researchersgeneticallymodifyacowtoproducemilkwithnobetalactoglobulin,

    whichistheproteinbelievedtotriggerallergicreactionsin23%ofinfants.

    4.4

    Researchersgeneticallyengineerabaldchicken(i.e.,nofeathers)toreducethe

    costofchickenmeatproduction.

    5.9

    FirstResponseTM augmentsitsathomepregnancyteststoincludeatestfor

    whetherababywillhaveTaySachsdisease.

    4.0

    FirstResponseTM augmentsitsathomepregnancyteststoincludeatestfor

    whetherababywillbeaboyoragirl.

    5.4

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    Psycho-stimulants to Improve Focus and Cognitive Function

    Ethics are well-founded standards of right and wrong that prescribe what humans oughtto do, usually in terms of rights, obligations, benefits to society, fairness, or specificvirtues. What is Ethics?, Issues in Ethics, IIE V1 N1 (Fall 1987); https://books.google.com/ngrams

    RightsDo we havethe right tomake thisdecision onbehalf of ourchildren?

    ObligationsDo we have theobligation to ourchildren to augmentthem if the drugsenable that?

    Benefits to societyDoes improvingchildrens performanceyield benefits tosociety that outweighthe costs?

    FairnessIs it fairto augmentsome children but notothers? Is access to thedrugs fairly distributedacross society?

    Parentsof

    children

    diagnosed

    with

    attention

    deficit

    disorder

    provide

    their

    children

    withpsychostimulant drugstoimprovetheirfocusandcognitivefunction.

    ParentsofchildrenNOTdiagnosedwithattentiondeficitdisorderprovidetheir

    childrenwithpsychostimulant drugstoimprovetheirfocusandcognitivefunction.

    Considerations:

    - The differentiator is the diagnosis.- Are the children becoming normal or supernormal? Where is the line?- Are there side effects? Which stimulant?- Who is making the decision?

    Psycho-stimulants to improve focus and cognitive function

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    Human Augmentation to Improve Sports Performance

    Obligations

    Are we obligated to play

    the game according toour natural abilities, orcan we augment them?

    Benefits to society

    Does enhanced baseball player

    performance yield benefits tosociety that outweigh thecosts? What are the costs?

    Fairness

    Is it fairto alter your

    body via surgery ordrugs to improveathletic performance?

    AbaseballplayerundergoesLasiksurgery

    toimprovehisbatting.

    Abaseballplayerusessteroidstoimprove

    hisbatting.

    Considerations:- The differentiator is the nature of the augmentation.- Are the players becoming normal or supernormal? Is an unfair advantage gained?

    - Are there side effects?

    Human augmentation to improve sports performance

    Fairness may turn on whether the augmentation restores normal function or

    exceeds it. Or it may turn on whether everyone else is doing it.

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    Human Augmentation to Improve Sports Performance

    http://www.baseballssteroidera.com/bse-memorable-quotes-steroid-related.html

    I would say there are only a couple of guyson a team that don't take greenies (speed)before a game. One or two guys. That's

    called going out there naked. And you hear itall the time from teammates, 'You're notgoing to play naked, are you?'

    Ken Caminiti,former MajorLeague Baseballplayer, admitted

    steroid user (deadof substanceabuse at age 41.)

    At the time, no. I viewed it as a levelplaying field. I looked up the definition ofcheat. The definition of cheat is to gain anadvantage over a rival or foe. I didn't do

    that. I viewed it as a level playing field.

    Lance Armstrong,former Tour de Francewinner, on whether hefelt that his doping

    constituted cheating

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    Genetic Modification of Animals

    http://www.baseballssteroidera.com/bse-memorable-quotes-steroid-related.html

    Researchersgeneticallymodifyacowto

    producemilkwithnobetalactoglobulin,

    whichistheproteinbelievedtotrigger

    allergic

    reactions

    in

    2

    3%

    of

    infants.Researchersgeneticallyengineerabald

    chicken(i.e.,nofeathers)toreducethecost

    ofchickenmeatproduction.

    Considerations:- The differentiators are how is the animal changed andfor what purpose?

    - Is this different from more traditional breeding / artificialselection? Does precedent matter?

    Genetic modif ication of animals

    Rights

    Do we havethe right togeneticallyalter animals?

    Obligations

    Do we have theobligation to producehealthier and cheaperfood if we can?

    Benefits to society

    Does modifying theanimals yield benefitsto society thatoutweigh the costs?

    Fairness

    Is it fairtothe animalsto alterthem?

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    Prenatal Genetic Screening

    http://www.baseballssteroidera.com/bse-memorable-quotes-steroid-related.html

    FirstResponseTM augmentsitsathomepregnancy

    teststoincludeatestforwhetherababywill

    haveTaySachsdisease.

    FirstResponseTM augmentsitsathomepregnancy

    teststo

    include

    atest

    for

    whether

    ababy

    will

    be

    a

    boyoragirl.

    Considerations:- The differentiator is what information is revealed and how will it might be used.

    - Cultural issues come into play.- Does the maker of the test have ethical responsibility?

    Prenatal genetic screening

    Rights

    For what types ofconditions do wehave the right toscreen unbornchildren?

    Obligations

    For what types ofconditions do we havethe obligation to screenunborn children?

    Benefits to society

    Which yields morebenefits to society:screening or notscreening? Doesthis differ by culture?

    Fairness

    Is this fair(forthe child, for theparents, for thewealthy vs. thepoor)?

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    Prenatal Genetic Screening

    Whats different?

    Normative pressure to prefer sons over daughters in rural parts of India andChina.

    Gender determination technologies available (ultrasound) since 1980s.

    Figures for Indian state of Punjab. (see Rogers, Diffusion of Innovations, 5th ed., p. 117)

    Ratio of boy children to girl children

    in Punjab.

    1991: 114 to 100

    2001: 126 to 100http://www.gapminder.org/world/ (sex ratio 0-14 yrs; crude birth rate)

    Recent advancements in DNA sequencing permit sequencing of fetal genomeusing a blood sample from the expectant mother. If the data can meaningfully

    predict child characteristics

    There are some scenarios that areextremely troubling (regarding) who deserves to be born.

    Marcy Darnovsky, associateexecutive director of the Centerfor Genetics and Society

    http://www.nytimes.com/2012/06/07/health/tests-of-parents-are-used-to-map-genes-of-a-fetus.html

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    Norms and Ethics

    Societal norms are the rules that a group uses for appropriate and inappropriatevalues, beliefs, attitudes and behaviors. These rules may be explicit or implicit. Failure tofollow the rules can result in severe punishments, including exclusion from the group.(http://changingminds.org/explanations/theories/social_norms.htm)

    Norms and ethics may be codified as laws: Dont steal, dont commit murder, etc.

    Examples:

    Face the doors when riding on the elevator. Cheer an injured player as s/he leaves the

    field.

    Norms may not always be ethical, or have an ethical basis.

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    Norms and Ethics

    The ethics involved in the use of new technologies affects their emergence orlack thereof.

    No clear cut answers, but ethical issues can be forecast (somewhat) andtherefore planned for based on:

    - Rights- Obligations- Benefits to society- Fairness

    These may vary across cultures or demographic groups. Important forforecasting where a technology will be deemed appropriate.