-
Screening or not screening? prostate cancer- The Preliminary
Report of External-Beam Radiotherapy for Localized Prostate Cancer
at KL-CGMH-Treatment of hormone refractory prostate cancer-
-
9697 98 313435
Chart3
31
34
35
969798
313435
0
0
0
963196
9734
9835511510
16361632
96
97
00~3940~4950~5960~6970~7980
0044111222048
6%59%12%23%
97
98
00~3940~4950~5960~6970~7980
0031117451749
14%49%11%26%
98
00~3940~4950~5960~6970~7980969798
0121589313435
97 BLADDER
bladder case list97
NONameChart NoSexAge123456789101112
14147242/M812008012112312203202321
24210441M7120080221
34913434M8620080220
410397596M4920080320
54130940M5420080318
610397596M4920080324
77021167M7920080419
84089862M7220080512
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122620314F7520080805
134179377M6820080821
141985000M8120080825
154021144F6920080909
169540414M7020081103
174515462M9020081111
187058960M6820080918
194383581M7420081203
204844982M7020081203
214055005M6320081217
97 BLADDER
0
0
0
0
0
0
0
0
0
0
0
0
97
97PROSTATE
prostate case list97
NONameChart NoSexAge123456789101112
14357963M5620080109Stage II53256004753141
24542694M5720080102Stage IV
3309402M5820080116Stage II
44259089M6020080428Stage IV
57018743M6320080220Stage II
67115157M6320080220Stage II
7311213M6520080314Stage II
84025828M662008
94110891M6620080422Stage IV
104295952/M6620080513Stage IV
118789160M6720080428Stage II
124026401M6720080512Stage III
134325598M6720080516Stage II
141426305M6820080517Stage IV
154803486M7020080529Stage IV
164252208M7020080331Stage II2008212008242009(1-5)5
174324917M7620080804Stage IV809026
184278371M7620080811Stage II724
194332824M7620080804Stage II8.752.2215.3
204547517M7620080823Stage III000
214395349M7620080905Stage II000
224294275M7720080915Stage II909026
234384916M7720080923Stage I100100100
247135777M7720080917Stage II
259802024M7720081014Stage II200720082009
264189335M7820081021Stage II413511
274836529M7820081023Stage IV
2820850864M791869304Stage II200720082009
291869304M7920081027Stage II21245
304879163M7920080902Stage II
314097376M7920081112Stage I200720082009
324109414M8120081203Stage III182410
334051267M8320081208Stage II
347050334M8320081203Stage II
354078244/M8420080908Stage III
97PROSTATE
0
0
0
0
0
0
0
0
0
0
0
0
97
97 KIDNEY
KIDNEY case list97
NONameChart Nosexage123456789101112
13924053M752008010810101303242118
2311213M772008321
34938117M392008518
44032439M522008618
54065524M782008623
64317904M852008618
74547073M4620080820
84202264F7320090822
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114299796M8020080910
124809483M5220081008
134294342F7520081008
147012501F7620081016
154057211F7320081029
164255411F33200811
177114340M5420081127
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97 KIDNEY
0
0
0
0
0
0
0
0
0
0
0
0
97
98 PROSTATE
prostate case list2008
NONameChart NoSexAge123456789101112
84242108M6920090421Stage I
154201011M6920090807Stage I
114116638M7520090609Stage I
234082143M8220091019Stage I7
124398724M8820090727Stage I
334070641M5520091226Stage II
264823964M5720091021Stage II0
3410516275M6120091230Stage II
274858272M6920091106Stage II0
161214335M7720090815Stage II
354190390M8120091226Stage II
254357817M8520091019Stage II0
294033026M8520090923Stage II100
284028404M8720091107Stage II90
174255480M9420090713Stage II200835
301058155M9420091116Stage II
214532108M4920091007Stage II2008
34550155M622009123Stage II
54368668M622009325Stage II
10493185M6720090606Stage II
24924143M722009122Stage II
14550795M742009121Stage II30132243363535
324839989M6220091202Stage III
144882052M6420090810Stage III
134036421M6820090731Stage III
184539164M6920090706Stage III200824
194169306M6120090920Stage IV200831
74397999M6520090515Stage IV
224868045M6520091030Stage IV90
68926803M682009413Stage IV
204048073M7520090901Stage IV
94127170M7620090515Stage IV
244068739M7720091019Stage IV
314177872M7720091212Stage IV
47186238M932009426Stage IV
98 PROSTATE
2008
98 KIDNEY
KIDNEY case list98
NONameChart NoSexAge123456789101112
14109853F842009010812442325123231
24278266F6020090217
34938923F5020090225
44035225F7120090303
54155148M6120090318
64549967M8220090323
74804373F7320090325
83313357F4320090413
97115514M3920090430
10947591M4820090428
117013676M5220090421
122630385M6520090526
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144238784F8120090601
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2639000037F6120091103
274150751M7620090716
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314255694M5420091211
98 KIDNEY
0
0
0
0
0
0
0
0
0
0
0
0
98
98BLADDER
BLADDER case list98
NONameChart NoSexAge123456789101112
14308700M722009011311251120322424
24010752F8320090207
38589049F5320090321
47174078M7920090407
5555973M6320090411
64103414M5620090418
74275031M8120090416
8153250F8220090509
94837143M6220090328
101157179M8320090424
1120646310M6820090602
124082937M5920090716
13755982M8120090720
1420533978M5820090902
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172153641M7620091021
1810012850M7520091030
1920482537M6820091123
204050653F6120091120
2121052978F8220091202
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237153784M6820091212
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98BLADDER
0
0
0
0
0
0
0
0
0
0
0
0
98
99PROSTATE
NONamesexageChart No
1M68450954220100109Stage III
2M81303615201003Stage IV
3M80415673320100106Stage I
4M71485452120100125Stage IIA
5M812092650720100123Stage IV
6M74211496820100130Stage III
7M74483037620100212Stage I
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9M83423493220100305Stage IIB
10M70403867220100426Stage IIA
11M84483968120100420Stage I
12
99BLADDER
NONamesexageChart No
1M92427998520100212
2M83455883820100121
3F52406830520100212
4M642134647620100327
5M80715668120100422
99KIDNEY
NONameChart Nosexage
12084872569F20100111
22133172061M20100114
3990077260F20100209
4299036951M20100126
538782275F20100119
61054454153M20100206
7713636559M20100317
8407550370M20100309
9480736056M20100419
102035186060M20100408
96 PROSTATE
prostate case list
NONameChart NoSexage
14357963M7820071224Stage III
2142520M7120071126Stage II
31245751M7520071119Stage IV
44061157M6820071122Stage II
54050566M86Stage IV
64831656M7820071120Stage I
74340650M8120070901Stage II
84111493M7720071015Stage II
96332768M5420070924Stage II
104366134M8320070913Stage IV
114037323M7320070629Stage III
124346267M6520070808Stage II
132247695M7720070714Stage IV
144192947M7720070611Stage III
157111000M5420070626Stage IV
164814563M982007Stage IV
17287627M7220070315Stage IV
184041042M8220070406Stage I
1921008671M5820070411Stage IV
204292961M8020070414Stage III
214090677M8020070416Stage IV
224023123M5920070511Stage I
237075450M7420070122Stage I
244300647M8520070122Stage II
2510056431M8220070209Stage IV
261157039M6420070209Stage II
274155631M8520070309Stage II
284850855M8320070317Stage I
297065567M6920070312Stage III
304071908M8520070406Stage II
314071908M7820070413Stage II
-
--00~3940~4950~5960~6970~798096004411129700311174980121589
Chart1
000
001
432
41115
11178
1249
96
97
98
--
96
969798
31343500~3940~4950~5960~6970~7980
00441112
963196
9734
9835511510
16361632
96
97
00~3940~4950~5960~6970~7980
0044111222048
6%59%12%23%
97
98
00~3940~4950~5960~6970~7980
0031117451749
14%49%11%26%
98
00~3940~4950~5960~6970~7980969798
0121589313435
--
00~3940~4950~5960~6970~7980
00441112
00311174
0121589
000
000
000
000
000
000
96
97
98
--
97 BLADDER
bladder case list97
NONameChart NoSexAge123456789101112
14147242/M812008012112312203202321
24210441M7120080221
34913434M8620080220
410397596M4920080320
54130940M5420080318
610397596M4920080324
77021167M7920080419
84089862M7220080512
94840783M8420080517
104545535M4520080603
113045122M7020080616
122620314F7520080805
134179377M6820080821
141985000M8120080825
154021144F6920080909
169540414M7020081103
174515462M9020081111
187058960M6820080918
194383581M7420081203
204844982M7020081203
214055005M6320081217
97 BLADDER
0
0
0
0
0
0
0
0
0
0
0
0
97
97PROSTATE
prostate case list97
NONameChart NoSexAge123456789101112
14357963M5620080109Stage II53256004753141
24542694M5720080102Stage IV
3309402M5820080116Stage II
44259089M6020080428Stage IV
57018743M6320080220Stage II
67115157M6320080220Stage II
7311213M6520080314Stage II
84025828M662008
94110891M6620080422Stage IV
104295952/M6620080513Stage IV
118789160M6720080428Stage II
124026401M6720080512Stage III
134325598M6720080516Stage II
141426305M6820080517Stage IV
154803486M7020080529Stage IV
164252208M7020080331Stage II2008212008242009(1-5)5
174324917M7620080804Stage IV809026
184278371M7620080811Stage II724
194332824M7620080804Stage II8.752.2215.3
204547517M7620080823Stage III000
214395349M7620080905Stage II000
224294275M7720080915Stage II909026
234384916M7720080923Stage I100100100
247135777M7720080917Stage II
259802024M7720081014Stage II200720082009
264189335M7820081021Stage II413511
274836529M7820081023Stage IV
2820850864M791869304Stage II200720082009
291869304M7920081027Stage II21245
304879163M7920080902Stage II
314097376M7920081112Stage I200720082009
324109414M8120081203Stage III182410
334051267M8320081208Stage II
347050334M8320081203Stage II
354078244/M8420080908Stage III
97PROSTATE
0
0
0
0
0
0
0
0
0
0
0
0
97
97 KIDNEY
KIDNEY case list97
NONameChart Nosexage123456789101112
13924053M752008010810101303242118
2311213M772008321
34938117M392008518
44032439M522008618
54065524M782008623
64317904M852008618
74547073M4620080820
84202264F7320090822
94142261F7520080827
102184171F7420080910
114299796M8020080910
124809483M5220081008
134294342F7520081008
147012501F7620081016
154057211F7320081029
164255411F33200811
177114340M5420081127
184900525M4720081202
97 KIDNEY
0
0
0
0
0
0
0
0
0
0
0
0
97
98 PROSTATE
prostate case list2008
NONameChart NoSexAge123456789101112
84242108M6920090421Stage I
154201011M6920090807Stage I
114116638M7520090609Stage I
234082143M8220091019Stage I7
124398724M8820090727Stage I
334070641M5520091226Stage II
264823964M5720091021Stage II0
3410516275M6120091230Stage II
274858272M6920091106Stage II0
161214335M7720090815Stage II
354190390M8120091226Stage II
254357817M8520091019Stage II0
294033026M8520090923Stage II100
284028404M8720091107Stage II90
174255480M9420090713Stage II200835
301058155M9420091116Stage II
214532108M4920091007Stage II2008
34550155M622009123Stage II
54368668M622009325Stage II
10493185M6720090606Stage II
24924143M722009122Stage II
14550795M742009121Stage II30132243363535
324839989M6220091202Stage III
144882052M6420090810Stage III
134036421M6820090731Stage III
184539164M6920090706Stage III200824
194169306M6120090920Stage IV200831
74397999M6520090515Stage IV
224868045M6520091030Stage IV90
68926803M682009413Stage IV
204048073M7520090901Stage IV
94127170M7620090515Stage IV
244068739M7720091019Stage IV
314177872M7720091212Stage IV
47186238M932009426Stage IV
98 PROSTATE
0
0
0
0
0
0
0
0
0
0
0
0
2008
98 KIDNEY
KIDNEY case list98
NONameChart NoSexAge123456789101112
14109853F842009010812442325123231
24278266F6020090217
34938923F5020090225
44035225F7120090303
54155148M6120090318
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83313357F4320090413
97115514M3920090430
10947591M4820090428
117013676M5220090421
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144238784F8120090601
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174279457M8020090727
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204258511M7620090817
212306773F5820090903
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234827788M6920090831
248388578M8420091012
2520646310M6820091020
2639000037F6120091103
274150751M7620090716
287011186F7820091204
2921324605M5720091125
3021326630F7820091125
314255694M5420091211
98 KIDNEY
0
0
0
0
0
0
0
0
0
0
0
0
98
98BLADDER
BLADDER case list98
NONameChart NoSexAge123456789101112
14308700M722009011311251120322424
24010752F8320090207
38589049F5320090321
47174078M7920090407
5555973M6320090411
64103414M5620090418
74275031M8120090416
8153250F8220090509
94837143M6220090328
101157179M8320090424
1120646310M6820090602
124082937M5920090716
13755982M8120090720
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1810012850M7520091030
1920482537M6820091123
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237153784M6820091212
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98BLADDER
0
0
0
0
0
0
0
0
0
0
0
0
98
99PROSTATE
NONamesexageChart No
1M68450954220100109Stage III
2M81303615201003Stage IV
3M80415673320100106Stage I
4M71485452120100125Stage IIA
5M812092650720100123Stage IV
6M74211496820100130Stage III
7M74483037620100212Stage I
8M63431018620100312Stage IIA
9M83423493220100305Stage IIB
10M70403867220100426Stage IIA
11M84483968120100420Stage I
12
99BLADDER
NONamesexageChart No
1M92427998520100212
2M83455883820100121
3F52406830520100212
4M642134647620100327
5M80715668120100422
99KIDNEY
NONameChart Nosexage
12084872569F20100111
22133172061M20100114
3990077260F20100209
4299036951M20100126
538782275F20100119
61054454153M20100206
7713636559M20100317
8407550370M20100309
9480736056M20100419
102035186060M20100408
96 PROSTATE
prostate case list
NONameChart NoSexage
14357963M7820071224Stage III
2142520M7120071126Stage II
31245751M7520071119Stage IV
44061157M6820071122Stage II
54050566M86Stage IV
64831656M7820071120Stage I
74340650M8120070901Stage II
84111493M7720071015Stage II
96332768M5420070924Stage II
104366134M8320070913Stage IV
114037323M7320070629Stage III
124346267M6520070808Stage II
132247695M7720070714Stage IV
144192947M7720070611Stage III
157111000M5420070626Stage IV
164814563M982007Stage IV
17287627M7220070315Stage IV
184041042M8220070406Stage I
1921008671M5820070411Stage IV
204292961M8020070414Stage III
214090677M8020070416Stage IV
224023123M5920070511Stage I
237075450M7420070122Stage I
244300647M8520070122Stage II
2510056431M8220070209Stage IV
261157039M6420070209Stage II
274155631M8520070309Stage II
284850855M8320070317Stage I
297065567M6920070312Stage III
304071908M8520070406Stage II
314071908M7820070413Stage II
MBD001F08ED.xls
Chart3
31
34
35
969798
313435
0
0
0
963196
9734
9835511510
16361632
96
97
00~3940~4950~5960~6970~7980
0044111222048
6%59%12%23%
97
98
00~3940~4950~5960~6970~7980
0031117451749
14%49%11%26%
98
00~3940~4950~5960~6970~7980969798
0121589313435
97 BLADDER
bladder case list97
NONameChart NoSexAge123456789101112
14147242/M812008012112312203202321
24210441M7120080221
34913434M8620080220
410397596M4920080320
54130940M5420080318
610397596M4920080324
77021167M7920080419
84089862M7220080512
94840783M8420080517
104545535M4520080603
113045122M7020080616
122620314F7520080805
134179377M6820080821
141985000M8120080825
154021144F6920080909
169540414M7020081103
174515462M9020081111
187058960M6820080918
194383581M7420081203
204844982M7020081203
214055005M6320081217
97 BLADDER
0
0
0
0
0
0
0
0
0
0
0
0
97
97PROSTATE
prostate case list97
NONameChart NoSexAge123456789101112
14357963M5620080109Stage II53256004753141
24542694M5720080102Stage IV
3309402M5820080116Stage II
44259089M6020080428Stage IV
57018743M6320080220Stage II
67115157M6320080220Stage II
7311213M6520080314Stage II
84025828M662008
94110891M6620080422Stage IV
104295952/M6620080513Stage IV
118789160M6720080428Stage II
124026401M6720080512Stage III
134325598M6720080516Stage II
141426305M6820080517Stage IV
154803486M7020080529Stage IV
164252208M7020080331Stage II2008212008242009(1-5)5
174324917M7620080804Stage IV809026
184278371M7620080811Stage II724
194332824M7620080804Stage II8.752.2215.3
204547517M7620080823Stage III000
214395349M7620080905Stage II000
224294275M7720080915Stage II909026
234384916M7720080923Stage I100100100
247135777M7720080917Stage II
259802024M7720081014Stage II200720082009
264189335M7820081021Stage II413511
274836529M7820081023Stage IV
2820850864M791869304Stage II200720082009
291869304M7920081027Stage II21245
304879163M7920080902Stage II
314097376M7920081112Stage I200720082009
324109414M8120081203Stage III182410
334051267M8320081208Stage II
347050334M8320081203Stage II
354078244/M8420080908Stage III
97PROSTATE
0
0
0
0
0
0
0
0
0
0
0
0
97
97 KIDNEY
KIDNEY case list97
NONameChart Nosexage123456789101112
13924053M752008010810101303242118
2311213M772008321
34938117M392008518
44032439M522008618
54065524M782008623
64317904M852008618
74547073M4620080820
84202264F7320090822
94142261F7520080827
102184171F7420080910
114299796M8020080910
124809483M5220081008
134294342F7520081008
147012501F7620081016
154057211F7320081029
164255411F33200811
177114340M5420081127
184900525M4720081202
97 KIDNEY
0
0
0
0
0
0
0
0
0
0
0
0
97
98 PROSTATE
prostate case list2008
NONameChart NoSexAge123456789101112
84242108M6920090421Stage I
154201011M6920090807Stage I
114116638M7520090609Stage I
234082143M8220091019Stage I7
124398724M8820090727Stage I
334070641M5520091226Stage II
264823964M5720091021Stage II0
3410516275M6120091230Stage II
274858272M6920091106Stage II0
161214335M7720090815Stage II
354190390M8120091226Stage II
254357817M8520091019Stage II0
294033026M8520090923Stage II100
284028404M8720091107Stage II90
174255480M9420090713Stage II200835
301058155M9420091116Stage II
214532108M4920091007Stage II2008
34550155M622009123Stage II
54368668M622009325Stage II
10493185M6720090606Stage II
24924143M722009122Stage II
14550795M742009121Stage II30132243363535
324839989M6220091202Stage III
144882052M6420090810Stage III
134036421M6820090731Stage III
184539164M6920090706Stage III200824
194169306M6120090920Stage IV200831
74397999M6520090515Stage IV
224868045M6520091030Stage IV90
68926803M682009413Stage IV
204048073M7520090901Stage IV
94127170M7620090515Stage IV
244068739M7720091019Stage IV
314177872M7720091212Stage IV
47186238M932009426Stage IV
98 PROSTATE
2008
98 KIDNEY
KIDNEY case list98
NONameChart NoSexAge123456789101112
14109853F842009010812442325123231
24278266F6020090217
34938923F5020090225
44035225F7120090303
54155148M6120090318
64549967M8220090323
74804373F7320090325
83313357F4320090413
97115514M3920090430
10947591M4820090428
117013676M5220090421
122630385M6520090526
134066448F5020090530
144238784F8120090601
154339668F7220090605
164166351M8420090630
174279457M8020090727
1821284169M5520090810
19299956M7020090821
204258511M7620090817
212306773F5820090903
2221293784F7120090825
234827788M6920090831
248388578M8420091012
2520646310M6820091020
2639000037F6120091103
274150751M7620090716
287011186F7820091204
2921324605M5720091125
3021326630F7820091125
314255694M5420091211
98 KIDNEY
0
0
0
0
0
0
0
0
0
0
0
0
98
98BLADDER
BLADDER case list98
NONameChart NoSexAge123456789101112
14308700M722009011311251120322424
24010752F8320090207
38589049F5320090321
47174078M7920090407
5555973M6320090411
64103414M5620090418
74275031M8120090416
8153250F8220090509
94837143M6220090328
101157179M8320090424
1120646310M6820090602
124082937M5920090716
13755982M8120090720
1420533978M5820090902
154843162M5920090922
164026136M7220090907
172153641M7620091021
1810012850M7520091030
1920482537M6820091123
204050653F6120091120
2121052978F8220091202
228743882M6820091201
237153784M6820091212
248778649M5820091219
98BLADDER
0
0
0
0
0
0
0
0
0
0
0
0
98
99PROSTATE
NONamesexageChart No
1M68450954220100109Stage III
2M81303615201003Stage IV
3M80415673320100106Stage I
4M71485452120100125Stage IIA
5M812092650720100123Stage IV
6M74211496820100130Stage III
7M74483037620100212Stage I
8M63431018620100312Stage IIA
9M83423493220100305Stage IIB
10M70403867220100426Stage IIA
11M84483968120100420Stage I
12
99BLADDER
NONamesexageChart No
1M92427998520100212
2M83455883820100121
3F52406830520100212
4M642134647620100327
5M80715668120100422
99KIDNEY
NONameChart Nosexage
12084872569F20100111
22133172061M20100114
3990077260F20100209
4299036951M20100126
538782275F20100119
61054454153M20100206
7713636559M20100317
8407550370M20100309
9480736056M20100419
102035186060M20100408
96 PROSTATE
prostate case list
NONameChart NoSexage
14357963M7820071224Stage III
2142520M7120071126Stage II
31245751M7520071119Stage IV
44061157M6820071122Stage II
54050566M86Stage IV
64831656M7820071120Stage I
74340650M8120070901Stage II
84111493M7720071015Stage II
96332768M5420070924Stage II
104366134M8320070913Stage IV
114037323M7320070629Stage III
124346267M6520070808Stage II
132247695M7720070714Stage IV
144192947M7720070611Stage III
157111000M5420070626Stage IV
164814563M982007Stage IV
17287627M7220070315Stage IV
184041042M8220070406Stage I
1921008671M5820070411Stage IV
204292961M8020070414Stage III
214090677M8020070416Stage IV
224023123M5920070511Stage I
237075450M7420070122Stage I
244300647M8520070122Stage II
2510056431M8220070209Stage IV
261157039M6420070209Stage II
274155631M8520070309Stage II
284850855M8320070317Stage I
297065567M6920070312Stage III
304071908M8520070406Stage II
314071908M7820070413Stage II
-
96 511 51016%36 %16 %32 %
97 220486%59%12%23%
98 5174914%49%11%26%
-
9616%36 %16 %32 %976%59%12%23%9814%49%11%26%
Chart1
0.160.060.14
0.360.590.49
0.160.120.11
0.320.230.26
96
97
98
--
(2)
96
511 510
16%36%16%32%
97
9616%36%16%32%
22048976%59%12%23%
6%59%12%23%9814%49%11%26%
98
51749
14%49%11%26%
(2)
000
000
000
000
96
97
98
--
(1)
--
96979800~3940~4950~5960~6970~7980
3134359600441112
9700311174
980121589
(1)
000
001
432
41115
11178
1249
96
97
98
--
963196
9734
9835511 510
16%361632
96
97
00~3940~4950~5960~6970~7980
0044111222048
6%59%12%23%
97
98
00~3940~4950~5960~6970~7980
0031117451749
14%49%11%26%
98
00~3940~4950~5960~6970~7980969798
0121589313435
--
00~3940~4950~5960~6970~7980
9600441112
9700311174
980121589
97 BLADDER
bladder case list97
NONameChart NoSexAge123456789101112
14147242/M812008012112312203202321
24210441M7120080221
34913434M8620080220
410397596M4920080320
54130940M5420080318
610397596M4920080324
77021167M7920080419
84089862M7220080512
94840783M8420080517
104545535M4520080603
113045122M7020080616
122620314F7520080805
134179377M6820080821
141985000M8120080825
154021144F6920080909
169540414M7020081103
174515462M9020081111
187058960M6820080918
194383581M7420081203
204844982M7020081203
214055005M6320081217
97 BLADDER
1
2
3
1
2
2
0
3
2
0
2
3
97
97PROSTATE
prostate case list97
NONameChart NoSexAge123456789101112
14357963M5620080109Stage II53256004753141
24542694M5720080102Stage IV
3309402M5820080116Stage II
44259089M6020080428Stage IV
57018743M6320080220Stage II
67115157M6320080220Stage II
7311213M6520080314Stage II
84025828M662008
94110891M6620080422Stage IV
104295952/M6620080513Stage IV
118789160M6720080428Stage II
124026401M6720080512Stage III
134325598M6720080516Stage II
141426305M6820080517Stage IV
154803486M7020080529Stage IV
164252208M7020080331Stage II2008212008242009(1-5)5
174324917M7620080804Stage IV809026
184278371M7620080811Stage II724
194332824M7620080804Stage II8.752.2215.3
204547517M7620080823Stage III000
214395349M7620080905Stage II000
224294275M7720080915Stage II909026
234384916M7720080923Stage I100100100
247135777M7720080917Stage II
259802024M7720081014Stage II200720082009
264189335M7820081021Stage II413511
274836529M7820081023Stage IV
2820850864M791869304Stage II200720082009
291869304M7920081027Stage II21245
304879163M7920080902Stage II
314097376M7920081112Stage I200720082009
324109414M8120081203Stage III182410
334051267M8320081208Stage II
347050334M8320081203Stage II
354078244/M8420080908Stage III
97PROSTATE
0
0
0
0
0
0
0
0
0
0
0
0
97
97 KIDNEY
KIDNEY case list97
NONameChart Nosexage123456789101112
13924053M752008010810101303242118
2311213M772008321
34938117M392008518
44032439M522008618
54065524M782008623
64317904M852008618
74547073M4620080820
84202264F7320090822
94142261F7520080827
102184171F7420080910
114299796M8020080910
124809483M5220081008
134294342F7520081008
147012501F7620081016
154057211F7320081029
164255411F33200811
177114340M5420081127
184900525M4720081202
97 KIDNEY
1
0
1
0
1
3
0
3
2
4
2
1
97
98 PROSTATE
prostate case list2008
NONameChart NoSexAge123456789101112
84242108M6920090421Stage I
154201011M6920090807Stage I
114116638M7520090609Stage I
234082143M8220091019Stage I7
124398724M8820090727Stage I
334070641M5520091226Stage II
264823964M5720091021Stage II0
3410516275M6120091230Stage II
274858272M6920091106Stage II0
161214335M7720090815Stage II
354190390M8120091226Stage II
254357817M8520091019Stage II0
294033026M8520090923Stage II100
284028404M8720091107Stage II90
174255480M9420090713Stage II200835
301058155M9420091116Stage II
214532108M4920091007Stage II2008
34550155M622009123Stage II
54368668M622009325Stage II
10493185M6720090606Stage II
24924143M722009122Stage II
14550795M742009121Stage II30132243363535
324839989M6220091202Stage III
144882052M6420090810Stage III
134036421M6820090731Stage III
184539164M6920090706Stage III200824
194169306M6120090920Stage IV200831
74397999M6520090515Stage IV
224868045M6520091030Stage IV90
68926803M682009413Stage IV
204048073M7520090901Stage IV
94127170M7620090515Stage IV
244068739M7720091019Stage IV
314177872M7720091212Stage IV
47186238M932009426Stage IV
98 PROSTATE
0
0
0
0
0
0
0
0
0
0
0
0
2008
98 KIDNEY
KIDNEY case list98
NONameChart NoSexAge123456789101112
14109853F842009010812442325123231
24278266F6020090217
34938923F5020090225
44035225F7120090303
54155148M6120090318
64549967M8220090323
74804373F7320090325
83313357F4320090413
97115514M3920090430
10947591M4820090428
117013676M5220090421
122630385M6520090526
134066448F5020090530
144238784F8120090601
154339668F7220090605
164166351M8420090630
174279457M8020090727
1821284169M5520090810
19299956M7020090821
204258511M7620090817
212306773F5820090903
2221293784F7120090825
234827788M6920090831
248388578M8420091012
2520646310M6820091020
2639000037F6120091103
274150751M7620090716
287011186F7820091204
2921324605M5720091125
3021326630F7820091125
314255694M5420091211
98 KIDNEY
0
0
0
0
0
0
0
0
0
0
0
0
98
98BLADDER
BLADDER case list98
NONameChart NoSexAge123456789101112
14308700M722009011311251120322424
24010752F8320090207
38589049F5320090321
47174078M7920090407
5555973M6320090411
64103414M5620090418
74275031M8120090416
8153250F8220090509
94837143M6220090328
101157179M8320090424
1120646310M6820090602
124082937M5920090716
13755982M8120090720
1420533978M5820090902
154843162M5920090922
164026136M7220090907
172153641M7620091021
1810012850M7520091030
1920482537M6820091123
204050653F6120091120
2121052978F8220091202
228743882M6820091201
237153784M6820091212
248778649M5820091219
98BLADDER
0
0
0
0
0
0
0
0
0
0
0
0
98
99PROSTATE
NONamesexageChart No
1M68450954220100109Stage III
2M81303615201003Stage IV
3M80415673320100106Stage I
4M71485452120100125Stage IIA
5M812092650720100123Stage IV
6M74211496820100130Stage III
7M74483037620100212Stage I
8M63431018620100312Stage IIA
9M83423493220100305Stage IIB
10M70403867220100426Stage IIA
11M84483968120100420Stage I
12
99BLADDER
NONamesexageChart No
1M92427998520100212
2M83455883820100121
3F52406830520100212
4M642134647620100327
5M80715668120100422
99KIDNEY
NONameChart Nosexage
12084872569F20100111
22133172061M20100114
3990077260F20100209
4299036951M20100126
538782275F20100119
61054454153M20100206
7713636559M20100317
8407550370M20100309
9480736056M20100419
102035186060M20100408
96 PROSTATE
prostate case list
NONameChart NoSexage
14357963M7820071224Stage III
2142520M7120071126Stage II
31245751M7520071119Stage IV
44061157M6820071122Stage II
54050566M86Stage IV
64831656M7820071120Stage I
74340650M8120070901Stage II
84111493M7720071015Stage II
96332768M5420070924Stage II
104366134M8320070913Stage IV
114037323M7320070629Stage III
124346267M6520070808Stage II
132247695M7720070714Stage IV
144192947M7720070611Stage III
157111000M5420070626Stage IV
164814563M982007Stage IV
17287627M7220070315Stage IV
184041042M8220070406Stage I
1921008671M5820070411Stage IV
204292961M8020070414Stage III
214090677M8020070416Stage IV
224023123M5920070511Stage I
237075450M7420070122Stage I
244300647M8520070122Stage II
2510056431M8220070209Stage IV
261157039M6420070209Stage II
274155631M8520070309Stage II
284850855M8320070317Stage I
297065567M6920070312Stage III
304071908M8520070406Stage II
314071908M7820070413Stage II
MBD001F08ED.xls
Chart3
31
34
35
969798
313435
0
0
0
963196
9734
9835511510
16361632
96
97
00~3940~4950~5960~6970~7980
0044111222048
6%59%12%23%
97
98
00~3940~4950~5960~6970~7980
0031117451749
14%49%11%26%
98
00~3940~4950~5960~6970~7980969798
0121589313435
97 BLADDER
bladder case list97
NONameChart NoSexAge123456789101112
14147242/M812008012112312203202321
24210441M7120080221
34913434M8620080220
410397596M4920080320
54130940M5420080318
610397596M4920080324
77021167M7920080419
84089862M7220080512
94840783M8420080517
104545535M4520080603
113045122M7020080616
122620314F7520080805
134179377M6820080821
141985000M8120080825
154021144F6920080909
169540414M7020081103
174515462M9020081111
187058960M6820080918
194383581M7420081203
204844982M7020081203
214055005M6320081217
97 BLADDER
0
0
0
0
0
0
0
0
0
0
0
0
97
97PROSTATE
prostate case list97
NONameChart NoSexAge123456789101112
14357963M5620080109Stage II53256004753141
24542694M5720080102Stage IV
3309402M5820080116Stage II
44259089M6020080428Stage IV
57018743M6320080220Stage II
67115157M6320080220Stage II
7311213M6520080314Stage II
84025828M662008
94110891M6620080422Stage IV
104295952/M6620080513Stage IV
118789160M6720080428Stage II
124026401M6720080512Stage III
134325598M6720080516Stage II
141426305M6820080517Stage IV
154803486M7020080529Stage IV
164252208M7020080331Stage II2008212008242009(1-5)5
174324917M7620080804Stage IV809026
184278371M7620080811Stage II724
194332824M7620080804Stage II8.752.2215.3
204547517M7620080823Stage III000
214395349M7620080905Stage II000
224294275M7720080915Stage II909026
234384916M7720080923Stage I100100100
247135777M7720080917Stage II
259802024M7720081014Stage II200720082009
264189335M7820081021Stage II413511
274836529M7820081023Stage IV
2820850864M791869304Stage II200720082009
291869304M7920081027Stage II21245
304879163M7920080902Stage II
314097376M7920081112Stage I200720082009
324109414M8120081203Stage III182410
334051267M8320081208Stage II
347050334M8320081203Stage II
354078244/M8420080908Stage III
97PROSTATE
0
0
0
0
0
0
0
0
0
0
0
0
97
97 KIDNEY
KIDNEY case list97
NONameChart Nosexage123456789101112
13924053M752008010810101303242118
2311213M772008321
34938117M392008518
44032439M522008618
54065524M782008623
64317904M852008618
74547073M4620080820
84202264F7320090822
94142261F7520080827
102184171F7420080910
114299796M8020080910
124809483M5220081008
134294342F7520081008
147012501F7620081016
154057211F7320081029
164255411F33200811
177114340M5420081127
184900525M4720081202
97 KIDNEY
0
0
0
0
0
0
0
0
0
0
0
0
97
98 PROSTATE
prostate case list2008
NONameChart NoSexAge123456789101112
84242108M6920090421Stage I
154201011M6920090807Stage I
114116638M7520090609Stage I
234082143M8220091019Stage I7
124398724M8820090727Stage I
334070641M5520091226Stage II
264823964M5720091021Stage II0
3410516275M6120091230Stage II
274858272M6920091106Stage II0
161214335M7720090815Stage II
354190390M8120091226Stage II
254357817M8520091019Stage II0
294033026M8520090923Stage II100
284028404M8720091107Stage II90
174255480M9420090713Stage II200835
301058155M9420091116Stage II
214532108M4920091007Stage II2008
34550155M622009123Stage II
54368668M622009325Stage II
10493185M6720090606Stage II
24924143M722009122Stage II
14550795M742009121Stage II30132243363535
324839989M6220091202Stage III
144882052M6420090810Stage III
134036421M6820090731Stage III
184539164M6920090706Stage III200824
194169306M6120090920Stage IV200831
74397999M6520090515Stage IV
224868045M6520091030Stage IV90
68926803M682009413Stage IV
204048073M7520090901Stage IV
94127170M7620090515Stage IV
244068739M7720091019Stage IV
314177872M7720091212Stage IV
47186238M932009426Stage IV
98 PROSTATE
2008
98 KIDNEY
KIDNEY case list98
NONameChart NoSexAge123456789101112
14109853F842009010812442325123231
24278266F6020090217
34938923F5020090225
44035225F7120090303
54155148M6120090318
64549967M8220090323
74804373F7320090325
83313357F4320090413
97115514M3920090430
10947591M4820090428
117013676M5220090421
122630385M6520090526
134066448F5020090530
144238784F8120090601
154339668F7220090605
164166351M8420090630
174279457M8020090727
1821284169M5520090810
19299956M7020090821
204258511M7620090817
212306773F5820090903
2221293784F7120090825
234827788M6920090831
248388578M8420091012
2520646310M6820091020
2639000037F6120091103
274150751M7620090716
287011186F7820091204
2921324605M5720091125
3021326630F7820091125
314255694M5420091211
98 KIDNEY
0
0
0
0
0
0
0
0
0
0
0
0
98
98BLADDER
BLADDER case list98
NONameChart NoSexAge123456789101112
14308700M722009011311251120322424
24010752F8320090207
38589049F5320090321
47174078M7920090407
5555973M6320090411
64103414M5620090418
74275031M8120090416
8153250F8220090509
94837143M6220090328
101157179M8320090424
1120646310M6820090602
124082937M5920090716
13755982M8120090720
1420533978M5820090902
154843162M5920090922
164026136M7220090907
172153641M7620091021
1810012850M7520091030
1920482537M6820091123
204050653F6120091120
2121052978F8220091202
228743882M6820091201
237153784M6820091212
248778649M5820091219
98BLADDER
0
0
0
0
0
0
0
0
0
0
0
0
98
99PROSTATE
NONamesexageChart No
1M68450954220100109Stage III
2M81303615201003Stage IV
3M80415673320100106Stage I
4M71485452120100125Stage IIA
5M812092650720100123Stage IV
6M74211496820100130Stage III
7M74483037620100212Stage I
8M63431018620100312Stage IIA
9M83423493220100305Stage IIB
10M70403867220100426Stage IIA
11M84483968120100420Stage I
12
99BLADDER
NONamesexageChart No
1M92427998520100212
2M83455883820100121
3F52406830520100212
4M642134647620100327
5M80715668120100422
99KIDNEY
NONameChart Nosexage
12084872569F20100111
22133172061M20100114
3990077260F20100209
4299036951M20100126
538782275F20100119
61054454153M20100206
7713636559M20100317
8407550370M20100309
9480736056M20100419
102035186060M20100408
96 PROSTATE
prostate case list
NONameChart NoSexage
14357963M7820071224Stage III
2142520M7120071126Stage II
31245751M7520071119Stage IV
44061157M6820071122Stage II
54050566M86Stage IV
64831656M7820071120Stage I
74340650M8120070901Stage II
84111493M7720071015Stage II
96332768M5420070924Stage II
104366134M8320070913Stage IV
114037323M7320070629Stage III
124346267M6520070808Stage II
132247695M7720070714Stage IV
144192947M7720070611Stage III
157111000M5420070626Stage IV
164814563M982007Stage IV
17287627M7220070315Stage IV
184041042M8220070406Stage I
1921008671M5820070411Stage IV
204292961M8020070414Stage III
214090677M8020070416Stage IV
224023123M5920070511Stage I
237075450M7420070122Stage I
244300647M8520070122Stage II
2510056431M8220070209Stage IV
261157039M6420070209Stage II
274155631M8520070309Stage II
284850855M8320070317Stage I
297065567M6920070312Stage III
304071908M8520070406Stage II
314071908M7820070413Stage II
-
The Preliminary Report of External-Beam Radiotherapy for
Localized Prostate Cancer at KL-CGMH 2010-8-13RTO
- 1. Prostate cancer:1) Long nature course2) Old age (median age=
75 y/o, rarely
- 3. According to Tx aggressiveness1) Active monitoring (low-risk
group and life expectancy
-
RT +- H/TAccording to the risk group1. Low-risk: no H/T is
needed2. Intermediate-risk or only single high-risk
factor(PSA>20) high-risk: 4-Ms short-term ADT(TAB): 2Ms
neoadjuvant + 2Ms concurrent H/T3. High-risk or very
high-risk(T3b/T4): at least 2-y long-term ADT (short-term + 20 Ms
adjuvant H/T) 1. LHRH antagonist + oral antiandrogen2. Orchiectomy
(T3b or N+; old age without sexual desire)
-
2007-1 ~2010-654 PCa patients received RT at KL-CGMH
NumberDose21Palliative intent3Curative post-op dose(60-66.6
Gy)30Curative Intent (>75 Gy)
-
Localized PCa27T4N0M1, GS= 8-9, PSA=20+ 78 Gy/39fx3: long-term
palliation all rapid biochemical failure after RT
-
Biochemical FailureIf patients received definitive RT +-
H/TNadir +2 ng/ml biochemical failure (End-point surrogate)2006-7
IJROBP
-
NCCN guidelines: (2010 V2)Low risk: 75.6 -79.2 GyOthers:78 - 80+
Gy
CMGH guidelines(Linkou/KL): 7560 cGy/42fx (before 2009-3)78.4
Gy/42fx (Linkou+KL-CGMH)
-
HDR+EBRT 79.6 Gy vs IMRT 75.6 Gy 3-Y BC= 91.7% vs 73.7%
(-18%)2009-3-10
-
Characteristics N=27Median age 70 y/o (range= 60-80)Median f/u
interval12 Ms (range=1-38)Risk Group Very-high High Intermediate
Low7 (26%)15 (56%)3 (11%)2 (7%)T-stage T1c T2a-c T3a-b T42 (7%)11
(41%)13 (48%)1 (4%)Gleason Score2-678-108 (30%)5 (18%)14
(52%)iPSA204 (15%)11 (41%)12 (44%)
-
RT technique IMRT RapidArc ()21 (78%)6 (22%)Median RT total
dose78.4 Gy/42fxMid-pelvic RT No Yes22 (82%)5 (18%)Hormone Therapy
None Not per-protocol Per-protocol4 (15%)13 (48%)10 (37%)Referral
Hospital KL-CGMH Linkou-CGMH 12 (44%)2 (7%)13 (48%)
-
Acute Adverse Effects
GI Gr0 Gr1 Gr211 (41%)12 (44%)4 (15%): mild diarrheaGU Gr0 Gr1
Gr2 Gr3 7 (26%)11 (41%)7 (26%)2 (7%): acute urine retention, RT
interruption)Perianal skin Gr0 Gr1 Gr220 (74%)(15%)3 (11%)
-
, 30 -> 350 cc IMRT () / Rapid Arc () = 7840 cGy/ 42
-
Chronic Adverse Effects
GI Gr0 Gr1 Gr224 (89%)2 (7%)1 (4%) (mild rectal bleeding)GU Gr0
Gr1 Gr2 Gr322 (81%)1 (4%)3 (11%)1 (4%) (urethral stricture: Hx of
TURP x3)
-
Sexual function
Pre-Tx 0 1 2 3 ?21 (78%)01 (4%)05 (18%)Post-Tx 0 ?22 (82%)5
(18%)
-
Nadir Achieved3 patients(+) Time to nadir achieved: 12Ms, 15Ms,
29Ms
-
Biochemical ControlFor all these 27 patientsno biochemical
failure at present
-
100%91%81%25%2007-7 UrologyCGMH-Linkou HDR+EBRT(~79.6 Gy) : 4-y
Biochemical-Free Survival
-
Overall Survival 1. 1 died of lung cancer and 1 died of liver
cirrhosis.
-
Thanks for your attentionRed Meat RR=2.64
- HRPCProgressive prostate cancer disease despite a castrate
testosterone level (
-
Treatment of HRPC1.Continue androgen suppression2.Palliative
chemotherapy3.Radiotherapy4.Other supportive treatment
- Androgen suppression1.Alternate hormone therapyCheck
testosterone level first If serum testosterone not at castration
level Additional hormone manipulation or orchiectomy If at
castration level, response to 2nd line hormone therapy
-
ChemotherapyNo indication or benefit of palliative chemotherapy
in the past until 1996. Mitoxantrone Plus Prednisolone was as first
approved by FDA.In 2004, Docetaxel in combination with Prednisolone
showed superior survival, improvement of QOL and pain control as
compared with Mitoxantrone Plus Prednisolone in several randomized
studies.Other active chemotherapy regimen included VP-16, CDDP,
Carboplatin, Estramustine, Atrasentan etc.Target therapy:
Sunitinib, Bevacizumab also showed clinical effect in HRPC pts.
-
Chemotherapy with Mitoxantrone plus Prednisolone or Prednisolone
after for Symptomatic Hormone-Resistant Prostate Cancer. Tannock. J
Chin Oncol 1996
590 HRPC pts RandomizedResult: M+P P Decrease in pain 29% 12%
Duration of pain relief 43 weeks 18 weeks Palliative response 38%
21%Mitoxantrone 12mg m2 Q3W, +Prednisolone (5) 1#Bid Prednisolone
(5) 1#Bid
-
Two large pivotal Phase III trials with docetaxel-based therapy
(TAX 327 and SWOG 9916) have demonstrated a survival benefit with
docetaxel chemotherapy for patients with metastatic CRPC
CRPC: Taxane-based chemotherapyTannock I, et al. N Engl J Med
2004;351:15021512Petrylak D, et al. N Engl J Med
2004;351:15131520
-
TAX327 trial 1006 metastatic HRPC ptsTannock I, et al. NEJM
2004Berthold DR, et al. J Clin Oncol 2008 ResultMedian survival :
19.2M (D3P);17.8M (D1P);16.3(MP)(P=0.004)Pain control: HR ratio in
favour of Docetaxel (0.78)Decline of PSA level: HR ratio :0.75
-
Berthold DR, et al. J Clin Oncol 2008;26:242245 Docetaxel
q3wDocetaxel qwMitoxantrone Median survival Hazard (months) ratio
p-valueDocetaxel q3w: 19.20.790.004Docetaxel qw:
17.80.870.086Mitoxantrone16.3
0.00.20.40.60.81.001234567YearsProbability of survivingTAX 327: 3
years survival analysis updated
-
Tannock I, et al. NEJM 2004: 351: 15021512Berthold DR, et al. J
Clin Oncol 2008;26:24245 17.4 (15.719.0)Mitoxantrone (n = 337) 201
(60%) 16.5 (14.418.6) 297 (88.1%) 16.3 (14.317.9) Docetaxel q3w (n
= 335) Docetaxel weekly (n = 334)Original data 2003 n (%) dead 166
(50%) 190 (57%) Median survival* 18.9 (17.021.2) Hazard ratio* 0.76
(0.620.94) 0.91 (0.751.11)pvalue 0.009 0.36 Updated data 2007 n (%)
dead 285 (85.1%) 285 (85.4%) Median survival* 19.2 (17.521.3) 17.8
(16.219.2)Hazard ratio* 0.79 (0.670.93) 0.87 (0.741.02) 0.004 0.09
pvalueTAX 327: initial vs updated analysis
-
Berthold DR, et al. J Clin Oncol 2008;26:24245 TAX 327: Survival
benefit across all subgroups
-
Summary of treatment of metastasis prostate Ca Androgen
suppression using bilateral orchiectomy or LHRH agonist should be
the first line treatment . Two weeks course of antiandrogen
treatment should be used to prevent disease flare on starting LHRH
agonist. Pts with HRPC should hold androgen suppression temporally.
After observation of androgen withdrawal syndrome, 2nd-line hormone
therapy (Different antiandrogen), 3rd-line (e.g. corticosteroid,
vit D,) even 4th-line hormone therapy (e.g. DES) should be
considered. Docetaxel (Q3W schedule) is the standard palliative
chemotherapy for HRPC, 2nd line chemotherapy or target therapy are
optional if failure of Docetaxel, but pts performance status is the
first consideration. Palliative radiotherapy or radioisotope
therapy (e.g. strontium-89)may be offered for painful bone
metastasis from HRPC.Bisphosphonates may decrease the risk of
complication for bone metastasis.
-
Thank You
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