Sampling of Interesting Dermatopathology Cases From CUMC-1

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    Sampling of interesting

    Dermatopathology cases from

    CUMC-1

    Deba P Sarma, MD

    Director of Dermatopathology

    Creighton University Medical Center

    Dept of Pathology, Omaha

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    F 55, obese

    4-month history of hemorrhagicdischarge from the umbilicus

    8-mm dark mass frombase of the umbilicus

    Case 1

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    Diagnosis: Lint ball omphalitis

    Ref:

    Sarma DP, Teruya B (2009). Lint ballomhphalitis, a rare cause of umbilicaldischarge in an adult woman: a casereport. Cases J 2: 7785.PMID 19830013

    Steinhauser G (2009). The nature of navelfluff. Med Hypotheses. 72(6):623-5.

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    M 50

    Possible pilar cyst removed from scalp.

    Case 2

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    RCC

    Immunostain

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    Implantation carcinoma of the scalp from renal

    cell carcinoma

    Ref:Sarma DP, Wang JF, McAllister MV, WangB, Shehan JM. (2008) Possible implantation

    carcinoma of the scalp following craniotomyfor metastatic renal cell carcinoma.Dermatology Online J 14(6):20.

    Diagnosis:

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    M 44, of Chinese heritage had red palmssince birth

    Mother (74 yrs) and daughter(7 yrs) hadbright red palms all their life

    Case 3

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    Erythema palmare hereditarium

    (Red palm disease, Lanes disease)

    Ref:

    Sarma DP, Wang B (2007). Erythemapalmare hereditarium (Red palms): Lanes

    Disease. Dermatol Online J. 13(2).

    Lane JE.(1929). Erythema palmare

    hereditarium. Arch Derm Syph. 20:445-448.

    Diagnosis

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    M 58, left knee dislocation with

    neurovascular injury, 1968.

    Left below the knee amputation, fitted with

    an artificial leg.

    36 years later (2004), pain at the amputation

    site, mass, foul discharge.

    Case 4

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    Verrucous carcinoma in the amputation stump

    Ref:Sarma DP, Hansen TP, Adickes ED(2006):

    Carcinoma arising in the leg amputation

    stump. The Internet J Dermatol 4(1).

    Diagnosis

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    Sarma DP, Weilbaecher TG.(1985))Carcinoma arising in burn scar. J SurgOncol. 29(2):89-90.

    M 60, left BK amputation 30 years ago after

    a dynamite explosion injury.

    Artificial leg since then.

    Developed squamous cell carcinoma on theamputation stump 30 years later.

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    F 32

    5 mm, painless subareolar nodule, left breast

    Case 5

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    Diagnosis:

    Infiltrating syringomatous eccrine

    adenoma of the nipple

    Ref:

    Sarma D, Stevens T (2009). Infiltrating

    syringomatous eccrine adenoma of thenipple: a case report. Cases J 2:0118.

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    Case 6

    F 83, 7-mm painless soft papule, left cheek,

    present for few months

    Clinical: Lipoma

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    CK 20 Chromogranin Synaptophysin

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    Diagnosis:

    Subcutaneous Merkel cell carcinoma

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    Case 7

    F 81

    Raised hyperkeratotic lesion, left temple,

    clinical sk

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    Ref:

    Sharma P, Sarma DP, Adickes ED (2006).

    Seborrheic keratosis with in-situ carcinoma

    changes. Dermatology Online J 12(7):19

    Diagnosis:

    Malignant seborrheic keratosis

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    Case 8

    M 86, back, clinical seborrheic keratosis

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    MITF

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    Diagnosis:

    Melanoma in-situ arising in seborrheickeratosis

    Ref:

    Repertinger S, Wang J, Adickes E, Sarma

    DP. (2008). Melanoma in-situ arising inseborrheic keratosis: a case report. Cases J

    1 (1):263.

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    Case 9

    M 72, farmer, sheep handler, left wrist

    crusted nodule, 0.9 cm.

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    Diagnosis: Human orf

    ( Ecthyma contagiosum,

    Contagious pustular

    dermatosis)

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    Three skin biopsies from the face of three

    men (age: 55-67yrs)

    Case 10

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    Winer L H.(1954). The dilated pore, a

    trichoepithelioma. J Invest Dermatol 23(3):181-

    188.

    Sarma Deba P.(2009): Dilated Pore of Winer, Dr.

    Louis H Winer and Wine Glass. The Internet

    Journal of Dermatology Vol 7(2).

    Ref