Upload
deba-p-sarma
View
216
Download
0
Embed Size (px)
Citation preview
7/29/2019 Sampling of Interesting Dermatopathology Cases From CUMC-1
1/32
Sampling of interesting
Dermatopathology cases from
CUMC-1
Deba P Sarma, MD
Director of Dermatopathology
Creighton University Medical Center
Dept of Pathology, Omaha
7/29/2019 Sampling of Interesting Dermatopathology Cases From CUMC-1
2/32
F 55, obese
4-month history of hemorrhagicdischarge from the umbilicus
8-mm dark mass frombase of the umbilicus
Case 1
7/29/2019 Sampling of Interesting Dermatopathology Cases From CUMC-1
3/32
7/29/2019 Sampling of Interesting Dermatopathology Cases From CUMC-1
4/32
Diagnosis: Lint ball omphalitis
Ref:
Sarma DP, Teruya B (2009). Lint ballomhphalitis, a rare cause of umbilicaldischarge in an adult woman: a casereport. Cases J 2: 7785.PMID 19830013
Steinhauser G (2009). The nature of navelfluff. Med Hypotheses. 72(6):623-5.
7/29/2019 Sampling of Interesting Dermatopathology Cases From CUMC-1
5/32
M 50
Possible pilar cyst removed from scalp.
Case 2
7/29/2019 Sampling of Interesting Dermatopathology Cases From CUMC-1
6/32
RCC
Immunostain
7/29/2019 Sampling of Interesting Dermatopathology Cases From CUMC-1
7/32
Implantation carcinoma of the scalp from renal
cell carcinoma
Ref:Sarma DP, Wang JF, McAllister MV, WangB, Shehan JM. (2008) Possible implantation
carcinoma of the scalp following craniotomyfor metastatic renal cell carcinoma.Dermatology Online J 14(6):20.
Diagnosis:
7/29/2019 Sampling of Interesting Dermatopathology Cases From CUMC-1
8/32
M 44, of Chinese heritage had red palmssince birth
Mother (74 yrs) and daughter(7 yrs) hadbright red palms all their life
Case 3
7/29/2019 Sampling of Interesting Dermatopathology Cases From CUMC-1
9/32
7/29/2019 Sampling of Interesting Dermatopathology Cases From CUMC-1
10/32
Erythema palmare hereditarium
(Red palm disease, Lanes disease)
Ref:
Sarma DP, Wang B (2007). Erythemapalmare hereditarium (Red palms): Lanes
Disease. Dermatol Online J. 13(2).
Lane JE.(1929). Erythema palmare
hereditarium. Arch Derm Syph. 20:445-448.
Diagnosis
7/29/2019 Sampling of Interesting Dermatopathology Cases From CUMC-1
11/32
M 58, left knee dislocation with
neurovascular injury, 1968.
Left below the knee amputation, fitted with
an artificial leg.
36 years later (2004), pain at the amputation
site, mass, foul discharge.
Case 4
7/29/2019 Sampling of Interesting Dermatopathology Cases From CUMC-1
12/32
7/29/2019 Sampling of Interesting Dermatopathology Cases From CUMC-1
13/32
Verrucous carcinoma in the amputation stump
Ref:Sarma DP, Hansen TP, Adickes ED(2006):
Carcinoma arising in the leg amputation
stump. The Internet J Dermatol 4(1).
Diagnosis
7/29/2019 Sampling of Interesting Dermatopathology Cases From CUMC-1
14/32
Sarma DP, Weilbaecher TG.(1985))Carcinoma arising in burn scar. J SurgOncol. 29(2):89-90.
M 60, left BK amputation 30 years ago after
a dynamite explosion injury.
Artificial leg since then.
Developed squamous cell carcinoma on theamputation stump 30 years later.
7/29/2019 Sampling of Interesting Dermatopathology Cases From CUMC-1
15/32
F 32
5 mm, painless subareolar nodule, left breast
Case 5
7/29/2019 Sampling of Interesting Dermatopathology Cases From CUMC-1
16/32
7/29/2019 Sampling of Interesting Dermatopathology Cases From CUMC-1
17/32
Diagnosis:
Infiltrating syringomatous eccrine
adenoma of the nipple
Ref:
Sarma D, Stevens T (2009). Infiltrating
syringomatous eccrine adenoma of thenipple: a case report. Cases J 2:0118.
7/29/2019 Sampling of Interesting Dermatopathology Cases From CUMC-1
18/32
Case 6
F 83, 7-mm painless soft papule, left cheek,
present for few months
Clinical: Lipoma
7/29/2019 Sampling of Interesting Dermatopathology Cases From CUMC-1
19/32
CK 20 Chromogranin Synaptophysin
7/29/2019 Sampling of Interesting Dermatopathology Cases From CUMC-1
20/32
Diagnosis:
Subcutaneous Merkel cell carcinoma
7/29/2019 Sampling of Interesting Dermatopathology Cases From CUMC-1
21/32
Case 7
F 81
Raised hyperkeratotic lesion, left temple,
clinical sk
7/29/2019 Sampling of Interesting Dermatopathology Cases From CUMC-1
22/32
7/29/2019 Sampling of Interesting Dermatopathology Cases From CUMC-1
23/32
Ref:
Sharma P, Sarma DP, Adickes ED (2006).
Seborrheic keratosis with in-situ carcinoma
changes. Dermatology Online J 12(7):19
Diagnosis:
Malignant seborrheic keratosis
7/29/2019 Sampling of Interesting Dermatopathology Cases From CUMC-1
24/32
Case 8
M 86, back, clinical seborrheic keratosis
7/29/2019 Sampling of Interesting Dermatopathology Cases From CUMC-1
25/32
MITF
7/29/2019 Sampling of Interesting Dermatopathology Cases From CUMC-1
26/32
Diagnosis:
Melanoma in-situ arising in seborrheickeratosis
Ref:
Repertinger S, Wang J, Adickes E, Sarma
DP. (2008). Melanoma in-situ arising inseborrheic keratosis: a case report. Cases J
1 (1):263.
7/29/2019 Sampling of Interesting Dermatopathology Cases From CUMC-1
27/32
Case 9
M 72, farmer, sheep handler, left wrist
crusted nodule, 0.9 cm.
7/29/2019 Sampling of Interesting Dermatopathology Cases From CUMC-1
28/32
7/29/2019 Sampling of Interesting Dermatopathology Cases From CUMC-1
29/32
Diagnosis: Human orf
( Ecthyma contagiosum,
Contagious pustular
dermatosis)
7/29/2019 Sampling of Interesting Dermatopathology Cases From CUMC-1
30/32
Three skin biopsies from the face of three
men (age: 55-67yrs)
Case 10
7/29/2019 Sampling of Interesting Dermatopathology Cases From CUMC-1
31/32
7/29/2019 Sampling of Interesting Dermatopathology Cases From CUMC-1
32/32
Winer L H.(1954). The dilated pore, a
trichoepithelioma. J Invest Dermatol 23(3):181-
188.
Sarma Deba P.(2009): Dilated Pore of Winer, Dr.
Louis H Winer and Wine Glass. The Internet
Journal of Dermatology Vol 7(2).
Ref