QUANTITATIVEAND QUALITATIVE IMPROVEMENT OF THE SHEEPMUTTON PRODUCTION WITH THE HELP OF MOLECULAR MARKER

AND GENOME EDITING TECHNOLOGY :A REVIEWSatish Kumar, Amar Singh Meena, Basanti Jyotsana, Rajiv Kumar and S. M. K. Naqvi

Animal Biotechnology Section, ICAR-Central Sheep and Wool Research Institute, Avika Nagar, Malpura-304501 (Rajasthan)

ABSTRACTThe objective of the study was to provide future prospects of molecular markers

and genome editing technology in the mutton production. In the country presently,Indian populations food habit are changing day by day and people are shifting towardsnon-vegetarian diet. The availability of the meat for human consumption is very lessaccording to daily minimum requirement. With the help of the molecular markers in

amarsingh23@gmail.com

Bhartiya Krishi Anushandhan Patrika, 31(4), 285-291, 2016

sheep breeding programme the per animal availability of meat can be increased withsame input without any additional loss of natural resources. The fecundity gene whichis playing major role in prolificacy identified in Garole and Kendrapada sheep breeds.This gene is introgressed in the other non-prolific sheep breeds in India like Deccaniand Malpura. After introgression of the fecundity gene and new born lambs in prolificsheep are selected on the basis of molecular marker at the time of birth. Due tofecundity gene the chance for two, three or four lambs in single lambing increases ascompared to their native breeds. This leads to quantitative improvement of the muttonproduction in sheep. In modern lifestyle diseases are emerging as a big threat tohuman being in India and world. There are several non-communicable diseases likediabetes, obesity, hypertension and hypotension, cancer and mental stress increasingtremendously. By the interventions in the food habitats in daily life, the modern lifestyle diseases in human being can be controlled delaye with the help of the genomeediting technology in sheep, quality of the mutton is improved. The incorporation of theomega-3 fatty acids synthesis gene and knockdown of myostatin gene in sheep hasimproved the quality of sheep mutton. Presently, several livestock based products qual-ity modifications according to human need based research is in progress in variousinstitution in India.

(Wool)

(Mutton) %

(ICMR)

(Molecular Marker) (Genome

Editing)

286

(ICAR)

(Booroola fecundity gene)

(NBAGR)

(Non-Prolific) (Breeds)

(Awassi) (Transfer)

(Prolific)

(Flock)

(Heterozygote)

(Homozygote) %(FecB)

(Litter size)

(Back-Cross)

%

% %

287

%

(Multiple purpose)

(FecB)

(SNP)

(Out of Season breeding)

(Lifestyle)

(Non-

Communicable diseases)

(Transgenic

Animal)

288

(Cloning)

(RNA interference)

(Texel)

(Genome editing)

(ZFN)(TALEAN)

(CRISPER/Cas9)

(Deep SeaFish)

(Existence)

(Value added products)

289

(Malnutrition)

(Resources)

(Conservation)

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290

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